Thursday 04 October
09:00

"Thursday 04 October"

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MOCCCS1
09:00 - 11:00

Session 1

09:00 - 09:15 Introducing the Cancer Research Center of Marseille. Jean Paul BORG (Director and team leader) (Keynote Speaker, Marseille, France)
09:15 - 09:30 The Oxford Cancer Center. Mark MIDDLETON (Head of Department) (Keynote Speaker, Oxford, United Kingdom)
09:30 - 09:50 Replication of a damaged DNA in bacteria and yeast. Vincent PAGES (Group leader) (Keynote Speaker, Marseille, France)
09:50 - 10:10 Roles of ZRANB3 in replication stress response. Dragana AHEL (Keynote Speaker, Oxford, United Kingdom)
10:10 - 10:30 Targeting the hypoxia-induced DNA damage response. Ester HAMMOND (Keynote Speaker, Oxford, United Kingdom)
10:30 - 11:00 DNA polymerase mutations in cancer. David CHURCH (Speaker) (Keynote Speaker, Oxford, United Kingdom)
11:30

"Thursday 04 October"

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MOCCCS2
11:30 - 12:50

Session 2

11:30 - 11:50 Mechanisms of DNA interstrand crosslink repair in humans. Martin COHN (Keynote Speaker, Oxford, United Kingdom)
11:50 - 12:10 Probing for the Achilles Heel of BRCA1- and BRCA2-mutated Tumours. Madalena TARSOUNAS (Keynote Speaker, Oxford, United Kingdom)
12:10 - 12:30 DNA damage and blood disorder. Christophe LACHAUD (Principal investigator) (Keynote Speaker, Marseille, France)
12:30 - 12:50 SLX4: Multitasking to maintain genome stability. Pierre Henri GAILLARD (Group leader) (Keynote Speaker, Marseille, France)
15:00

"Thursday 04 October"

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MOCCCS3
15:00 - 16:30

Session 3

15:00 - 15:20 Meiotic DNA recombination in yeast. Bertrand LLORENTE (PI) (Keynote Speaker, Marseille, France)
15:20 - 15:40 Metabolic signalling in the regulation of homologous recombination. Fumiko ESASHI (Keynote Speaker, Oxford, United Kingdom)
15:40 - 16:00 Transactions of the human DNA double-strand break repair machineries. Mauro MODESTI (principal investigator) (Keynote Speaker, Marseille, France)
16:00 - 16:30 DNA damage signalling in mitosis. Andrew YOUDELL (Keynote Speaker, Oxford, United Kingdom)
16:50

"Thursday 04 October"

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MCOCCC4
16:50 - 17:50

Session 4

16:50 - 17:10 53BP1 cooperation with the Rev7-Shieldin complex underpins DNA structure-specific NHEJ. Ross CHAPMAN (Keynote Speaker, Oxford, United Kingdom)
17:10 - 17:30 The Role of the chromatin remodelling factor atrx in telomere maintenance, genome stability and cancer. David CLYNES (Keynote Speaker, Oxford, United Kingdom)
17:30 - 17:50 The p21-mTert knock-in mouse: an in vivo model of senescence bypass via the conditional expression of telomerase. Vincent GELI (Group leader) (Keynote Speaker, Marseille, France)
Friday 05 October
09:00

"Friday 05 October"

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MOCCCS5
09:00 - 11:10

Session 5

09:00 - 09:25 The role of PARPs in DNA repair genome stability. Nicholas LAKIN (Keynote Speaker, Oxford, United Kingdom)
09:25 - 09:50 Integrated strategy for targeting Protein-Protein interactions with dedicated chemical libraries and computer-aided drug design. Xavier MORELLI (Group Leader) (Keynote Speaker, CRCM MARSEILLE, France)
09:50 - 10:15 DNA replication stress: Targeting the Achilles'heel of breast cancer Stem cells. Emmanuelle CHARAFFE JAUFFREY (Keynote Speaker, France)
10:15 - 10:45 PARP inhibitors and breast cancer. Antony GONCALVES (Head of Department) (Keynote Speaker, MARSEILLE, France)
10:45 - 11:10 Preliminary results of Chemogenomic analysis of AML: toward personalized medicine approaches in AML? Norbert VEY (HEAD LEUKEMIA SERVICE) (Keynote Speaker, MARSEILLE, France)
11:35

"Friday 05 October"

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MOCCCSWK
11:35 - 12:45

Workshop Session

11:35 - 12:00 Workshop Discussions.
12:00 - 12:25 Workshop outcomes.
12:25 - 12:45 Concluding remarks.