Monday 12 October
Time Auditorium Agnelli Room 500 Room Londra Room Istanbul Room Madrid Room Parigi Room Roma Room Atene Room Dublino
08:30
08:30-09:00
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KS1
Keynote Session 1

Keynote Session 1

Moderator: Pr Rick BODY (Professor of Emergency Medicine) (Manchester)
08:30 - 09:00 Goal directed medical education - creativity meets discipline. Victoria BRAZIL (Keynote Speaker, Australia)

09:10
09:10-10:40
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A21
State of the Art
Neurological Emergencies

State of the Art
Neurological Emergencies

Moderators: Stefano GRIFONI (Firenze, Italy), Andy JAGODA (USA)
09:10 - 09:40 Dizziness : a new evidence-based approach I. Jonathan EDLOW (Presenter, USA)
09:40 - 10:10 Dizziness : a new evidence-based approach II. Jonathan EDLOW (Presenter, USA)
10:10 - 10:40 Reversal of novel oral anticoagulants: what are the current options? Giancarlo AGNELLI (Presenter, Milano, Italy)

09:10-10:40
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B21
Italy invites
Competenze del team dell'urgenza

Italy invites
Competenze del team dell'urgenza

Moderators: Marilena CELANO (MILAN, Italy), Juricich ZORA (Italy)
09:10 - 09:30 Nuove strategie per la gestione dell'attesa. Luca GELATI (Presenter, Modena, Italy)
09:30 - 09:50 Le competenze infermieristiche in area critica. Elena MANA (Presenter, Pinerolo, Italy)
09:50 - 10:10 Le emergenze sociali in pronto Soccorso. Paolo MOSCATELLI (Presenter, Genova, Italy)
10:10 - 10:30 Metodologie mediche non convenzionali nell'urgenza. Mario RAVAGLIA (Presenter, Lugo, Italy)

09:10-10:40
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C21
Clinical Questions: Controversies
Disaster Medicine & Biohazards

Clinical Questions: Controversies
Disaster Medicine & Biohazards

Moderators: Pr Francesco DELLA CORTE (Head of Emergency Department) (Novara, Italy), Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Besançon, France)
09:10 - 09:40 Are we prepared to face emerging diseases: The Ebola case. Laurie MAZURIK (Presenter, TORONTO, Canada)
09:40 - 10:10 A multitude of volunteers in disaster response: Resource or problem? Patrick DREWS (research associate) (Presenter, Stuttgart, Germany)
10:10 - 10:40 Hospital triage in mass casualty incidents: A gain or loss of time? Pr Pinchas HALPERN (department chair) (Presenter, Tel Aviv, Israel, Israel)

09:10-10:40
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D21
EuSEM meets
ERC

EuSEM meets
ERC

Moderators: Maaret CASTREN (Professor) (HELSINKI, Finland), Marc SABBE (Medical staff member) (Leuven, Belgium)
09:10 - 10:40 What is ERC? Maaret CASTREN (Professor) (Presenter, HELSINKI, Finland)
09:10 - 10:40 Resuscitation academy. Maaret CASTREN (Professor) (Presenter, HELSINKI, Finland)
09:10 - 10:40 Resuscitation registries. Ian MACONOCHIE (Presenter, United Kingdom)
09:10 - 10:40 How long should we resuscitate? Marc SABBE (Medical staff member) (Presenter, Leuven, Belgium)

09:10-10:40
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E21
Administration / Management
Women in Emergency Medicine

Administration / Management
Women in Emergency Medicine

Moderators: Adela GOLEA (Associate Professor) (Cluj Napoca, Romania), Dr Barbara C HOGAN (Past President of the European Society for Emergency Medicine, EuSEM) (HAMBURG, Germany)
09:10 - 09:20 Introduction. Dr Barbara C HOGAN (Past President of the European Society for Emergency Medicine, EuSEM) (Presenter, HAMBURG, Germany)
09:20 - 09:45 Women leaders in EM. Judith TINTINALLI (Professor) (Presenter, Chapel Hill NC, USA)
09:45 - 10:15 Computer-aided female intuition. Tiziana MARGARIA STEFFEN (Presenter, Ireland)
10:15 - 10:40 The politics of managing emergency departments. Clara WU (Presenter, N.T., Hong Kong)

09:10-10:40
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F21
YEDM
Sim Wars

YEDM
Sim Wars

Moderators: Pier Luigi INGRASSIA (Lugano, Swaziland), François LECOMTE (PH) (Paris, France)
Coordinators: Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Coordinator, Besançon, France), Youri YORDANOV (Médecin) (Coordinator, Paris, France)

09:10-10:40
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G21
Paediatric Track
Paediatric Biomarkers and Vital Signs

Paediatric Track
Paediatric Biomarkers and Vital Signs

Moderators: Ian MACONOCHIE (United Kingdom), Pr Hezi WAISMAN (Director, Dept. of Emergency Medicine) (Petach-Tikva, Israel)
09:10 - 09:40 Are biomarkers useful in the management in children with fever at the ED? Alain GERVAIX (Presenter, Geneva, Switzerland)
09:40 - 10:10 The value of routine vital signs in children at the Emergency Department. Henriette MOLL (paediatrician) (Presenter, rotterdam, The Netherlands)
10:10 - 10:40 Panel discussion.

09:10-10:40
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OP1-21
Oral Paper 1
Cardiovascular Emergencies II

Oral Paper 1
Cardiovascular Emergencies II

Moderators: Veli-Pekka HARJOLA (Head of Department) (Helsinki, Finland), Timothy Hudson RAINER (Cardiff)
09:10 - 10:40 #1081 - #1081 - Revascularization strategy for acute coronary syndrome with ST-segment elevation: accessibility to angiography room and mortality.
#1081 - Revascularization strategy for acute coronary syndrome with ST-segment elevation: accessibility to angiography room and mortality.

Introduction: European Society of Cardiology advocate the period and management of coronary reperfusion, primary percutaneous coronary intervention (pPCI) or thrombolysis, according to the interval between the beginning of chest pain (symptoms onset) and the first medical contact (CP-FMC) and the availability of pPCI. The objective of the study was to investigate the mortality of acute coronary syndromes with ST-segment elevation (STEMI) according to the recommended time and availability of pPCI.

Materials and methods: Data collected on a regional level through a retrospective study managed by 8 out-of-hospital emergency medical services (EMS) and 40 mobile intensive care units (MICU). Inclusion criteria: data collected from 2003 to 2013, all uncomplicated STEMI with symptom onset < 12h, with a pre-hospital decision taken for direct pPCI, arriving alive at the hospital. The area was divided into three concentric zones: city, inner and outer suburb. Availability of PCI was defined as the concentration of cath lab per 100 km2. Time intervals were defined in three categories according to the guidelines: target time (pPCI < 60min if CP-FMC < 2h or < 90min if CP-FMC between 2h-12h), reasonable time (pPCI between 60 and 120 min if CP-FMC < 2h or between 90 and 120 min if CP-FMC between 2h-12h) and out of time in the other cases. Chi-2 test was used for testing the trends, statistical significance p < 0.05.

Results: Data on 10,210 patients were recorded in 10 years, 2,454 (24%) received thrombolysis and 7,756 (76%) pPCI. Availability of PCI was 9.5 per 100km² in city, 2 in inner suburb and 0.1 in outer suburb. A significant increase of out of time PCI was found when access to PCI decreased (city 6% < inner suburb 9% < outer suburb 14%). Time delay to PCI were in target time for 16% (n=1,619), in reasonable time for 49% (n=5,026) and out of time for 11% (n=1,111). Mortality was significantly (p<0.0001) related to increased reperfusion period: in “target time” mortality was 1.8% (n=28), in “reasonable time” 1.9% (n=94) and in “out of time” 4.3% (n=46). Data were missing or uninterpretable in 3% of cases.

Discussion: Management of STEMI reperfusion is in target time for 16% of patients and 65% within acceptable time. PPCI-related “out of time” delay increased when availability of pPCI decreased. The clinical impact of non-compliance with time intervals is a major significant increase in mortality. These objectives legitimized by international guidelines must be implemented and respected.


Laurent REBILLARD, Alexandre ALLONNEAU, Hugues LEFORT (Marseille), Lionel LAMHAUT, Aurélie LOYEAU, Sophie BATAILLE, François-Xavier LABORNE, Amandine ABRIAT, Yves LAMBERT, Jean-Michel JULIARD, Frédéric LAPOSTOLLE
09:10 - 10:40 #1116 - #1116 - Is the management of ST–segment elevation myocardial infarction in patient aged over 80 optimal?
#1116 - Is the management of ST–segment elevation myocardial infarction in patient aged over 80 optimal?

Introduction : The Acute Coronary Syndrome with ST- segment elevation (STEMI) is a priority in emergency medicine. Do patients >= 80 years benefit from a management comparable to that of younger patients?

Objectives: Compare the characteristics of management of STEMI patients >= 80 years and

Methods: Data are derived from a prospective registry that lists all STEMI managed within 24 hours by 8 out-of-hospital emergency medical services (SAMU) and 40 mobile intensive care units (MICU) in a region of France. Secondary transfers were excluded from the analysis. Statistical analysis: Chi-2 test and Wilcoxon test were used. Multivariate analysis with reference group patients over 80 years old.

Results: 18,093 STEMI were included from 2003 to 2013 with 2,502 (14%) being >= 80 years. The proportion of elderly patients is stable since 2003. There was a majority of women (51% were over 80 years). The call to SAMU is delayed after the beginning of pain, since this call is made on average after 93 minutes for those aged over 80 as opposed to 57 minutes. Given these delays, the occurrence of at least one criterion of gravity was more common in those aged more than 80 years (29% against 18% in those aged less than 80 years). During the treatment, the decision of an unclogging was less frequent in patients >= 80 years of age 83% against 97% in patients aged less than 80 years, but when the decision was taken to unclog, primary angioplasty was carried out similarly in both groups. After adjusting for sex, age < 80 years remains an independent criterion for decision-making of an unclogging (OR = 3.5 [3.1 to 4.0], p <0.0001). Pre-hospital mortality was therefore greater for those above 80 years (1.3% against 0.5%), similarly, in-hospital mortality (15.7% against 3.8% in those under 80 years).

Discussion: The management of STEMI patients >= 80 years was associated with less reperfusion decisions than in younger people. However, to call to SAMU allowed to take the decision of unclogging in 83% of cases. The lack of decision-making certainly contributes to the excess mortality among those aged >= 80 years.


Julian MORO, Isabelle KLEIN, Hugues LEFORT (Marseille), Sophie BATAILLE, Aurélie LOYEAU, François-Xavier LABORNE, Yann-Laurent VIOLIN, François DUPAS, Yves LAMBERT, Thévy BOCHE, Jean-Michel JULIARD
09:10 - 10:40 #1148 - #1148 - Pulmonary and venous ultrasonography improve the diagnostic accuracy of the Wells score in patients with pulmonary embolism.
#1148 - Pulmonary and venous ultrasonography improve the diagnostic accuracy of the Wells score in patients with pulmonary embolism.

Objective

Pulmonary embolism (PE) has a heterogeneous clinical presentation and international guidelines recommend the use of validated clinical scores to estimate the pre-test probability of PE. Recently, point-of-care ultrasonography has been widely used, proving to be accurate and useful in the diagnosis of deep venous thrombosis (DVT) and of many acute pulmonary pathologies. The aim of this multicentric prospective study is to compare the diagnostic accuracy of a clinical-ultrasonographic score (US-WS) with a clinical score as Wells score (WS).

Methods

We calculated the dichotomized WS (“PE likely” if >4 points, “PE unlikely” if ≤4) in consecutive adult patients suspected of PE presenting to four italian hospitals. In each patient lung and venous ultrasonography were performed by a physician blinded to clinical data. The US-WS differs from traditional WS in the following items: “signs and symptoms of DVT”, replaced by “evidence of DVT at venous lower limbs ultrasonography” and ”alternative diagnosis less likely than PE” replaced by ”alternative diagnosis less likely than PE after lung ultrasonography”. The last item was considered positive in presence of at least one subpleural infarct; in absence of lung infarcts and in case of an alternative echographic diagnosis such as pneumonia, pleural effusion or diffuse interstitial syndrome, the item was considered negative. Finally, in case of a normal lung US examination, the item had the same point assigned to the same item in the WS. Final diagnosis of was obtained by multidetector CT pulmonary angiography or when not feasible by lung scintigraphy and a 30 days clinical follow-up.

Results

Among the 339 enrolled patients, PE was finally diagnosed in 96 (28.3%). Two-hundred (59%) patients had a WS ≤4, and among them PE was present in 41 (20.5%). In the 139 patients (41%) with WS >4, PE was diagnosed in 55 (39.6%).  Lung and venous ultrasonography was performed in 7±3 minutes. US-WS was ≤4 in 247 patients (72.9%, p<0.05 vs WS), of which 30 (12.1%) had PE as final diagnosis. In the 92 patients with US-WS >4 (27.1%, p<0.05 vs WS), 66 (71.7%, p<0.05 vs WS) had PE as final diagnosis. US-WS reallocated 85 patient (25.1%), moving 66 patients from PE likely to PE unlikely (only 7 had PE) and 19 patients from PE unlikely to PE likely (18 had PE). Sensitivity (68.8%, 95% CI 58.5-77.8) and specificity (89.3%, 95%CI 84.7-92.9) of US-WS where significantly superior to sensitivity (57.3%, 95%CI 46.8-67.3) and specificity (65.4%, 95%CI 59.1-71.4) of Wells score (p<0.05 for both). The area under the curve of US-WS (86.6%, 95% CI 81.9-91.4) was significantly superior to that of WS (64.5%, 95% CI 57.7-71.2)  (p<0.05).

 Conclusion

The US-WS is rapidly feasible at the bedside, increases the proportion of low-risk patients with a better global accuracy compared to traditional WS.


Peiman NAZERIAN, Marco VITTORINI (Firenze, Italy), Chiara GIGLI, Emanuela GAMBETTA, Francesco Giuseppe SFERLAZZA, Baioni MICHELE, Valentina SALVATORI, Andrea NENCIONI, Simone VANNI, Stefano GRIFONI
09:10 - 10:40 #1260 - #1260 - Impact of off-hour presentation on process performances and outcomes in patients with ST-elevation myocardial infarction.
#1260 - Impact of off-hour presentation on process performances and outcomes in patients with ST-elevation myocardial infarction.

Background: Several studies examined the impact of off-hour presentation (cath lab staff available on call) on both the processing time of patients with ST-elevation myocardial infarction (STEMI) and the resulting outcomes. There is general agreement in the literature with regard to the importance of the processing timing of the patients, although data regarding increase in mortality as a function of processing timing are conflicting.

Objective: To evaluate the association between off-hour presentation, door-to-balloon time (D2B), first medical contact-to-device (FMC2D), total ischemic time (TIT) and in-hospital and 30 day mortality in patients with STEMI.

Methods and results: Through a retrospective analysis, we examined the medical records of patients admitted for STEMI documented within 12 hours from symptoms onset, who underwent an emergency PCI in a hub hospital in the period spanning from 01/01/11 to 12/31/14.

A total of 525 patients were included in the study; 352 of them (67%) reached to hospital in a moment of inactivity of the cath-lab (off-hour) with all or part of the staff not physically present, while 173 (33%) presented themselves during the hours of service of the cath-lab (on -hour).

The two groups were homogeneous for sex, age ≥75 years, cardiogenic shock, and bradycardia. The delay in seeking relief was similar in the two groups, significant differences emerged with regard to D2B, FMC2D and TIT; patients who arrived during off-hours showed longer D2B (median 65 'vs. 49', p<0.001), FMC2D (median 95.5 'vs 84 ', p<0.001): reperfusion was achieved less frequently in a time interval consistent with guidelines (≤ 90% FMC2D': 45.5% vs 56.2%, p=0.036, OR 0.65, 95 % CI 0.43 to 0.97); TIT was similar in the two groups (median 200 'vs 185', p=0.348).

These differences in time of reperfusion are confirmed after adjustment for age, sex, and access modality (emergency service vs self-presentation).

The in-hospital mortality was higher in patients presenting during off-hours (7.1% vs 2.3%, p=0.024, OR 3.24, 95% CI 1.11 to 9.46): 30 day mortality was also different although it did not reach the statistical significance (7.7% vs 3.4%, p=0.06, OR 2.33, 95% CI 0.94 to 5.74).

Conclusions: In our working setting patients with STEMI presenting during off-hours had revascularization times significantly higher: this data are associated with a significantly higher in-hospital mortality. These data highlight the need of improving the cath-labs organization as well as rationalize the allocation of resources in order to ensure adequate revascularization times to all patients with STEMI to improve significantly both clinical outcomes and survival.


Giovanni PERALTA (Anet), Nicola GLORIOSO, Fabrizio POLO, Umberto PISANO, Maurizio PORCU
09:10 - 10:40 #1269 - #1269 - Initial elevated blood glucose in acute heart failure syndrome: a prognostic factor.
#1269 - Initial elevated blood glucose in acute heart failure syndrome: a prognostic factor.

Background: Several biological prognostic indicators were analyzed in the acute heart failure syndrome (SICA) such as: hemoglobin, serum sodium, troponin levels…Initial hyperglycemia appears among these prognostic indicators (1).

Purpose: The objective of this work was to investigate the prognostic impact of the initial elevated blood glucose on mortality among patients with SICA admitted to the emergency department.

 Participants and methods: We conducted a single- center, prospective, observational study. Inclusion of patients with SICA. Standardization of treatment according to clinical scenario (CS). Hyperglycemia was defined as:

- Diabetic known patient or unknown but with HbA1C ≥ 6.5%:  hyperglycemia if glucose level ≥ 11mmol /L.

- No diabetes with HbA1C < 6.5%: hyperglycemia if glucose level ≥ 7mmol /L.

Results: One hundred eighty patients were included. Mean age= 66 ± 11 years [22-94]. Sex ratio= 1.27. Clinical history N (%): Hypertension 147 (81.7), known diabetes 124 (68.9). The distribution by clinical scenario N (%)   : CS1: 121 (67.2), CS2: 14 (7.8), CS4: 44 (24.4), and CS5: 1 (0.6). Twenty three patients had an HbA1C test which allowed tracking 8 unrecognized diabetes (HbA1C ≥ 6.5%). Average blood glucose concentration at admission was 15.65± 8.4 mmol/L [3.3 - 44]. The initial hyperglycemia was noted in 128 patients (71. 1%): 96 diabetic, 32 without diabetes. Overall 21 patients (11, 7%) died during 30 days of follow-up, 24 patients (13, 3%) died during 90 days of follow up. Mortality at one month was significantly elevated in patients with initial hyperglycemia [14, 8% (n= 19) vs 3, 8% (n=2); p = 0,041]. The same difference was demonstrated at 90 days follow –up [17,1% (n=22) vs 3,8 % (n =2 ); p = 0,016).

Conclusion: Elevated blood glucose concentrations at presentation are associated with one month and  three months mortality in acute heart failure syndrome admitted in emergency department.

 

(1): Mebazaa  and al . J Am Coll Cardiol 2013; xx: 1-10

 


Hela MANAI (Tunis, Tunisia), Sarra JOUINI, Kehna BOUZID GHOZZI, Dorra CHTOUROU, Rym HAMED, Imene BOUKHALFA, Khaled SAIDI, Bechir BOUHAJJA

09:10-10:40
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OP2-21
Oral Paper 2
Pain Management I

Oral Paper 2
Pain Management I

Moderators: Andrea FABBRI (Chief of Emergency Unit) (Forli, Italy), Sabine LEMOYNE (Clinical Head-Operational Lead) (Antwerp, Belgium)
09:10 - 10:40 #1150 - #1150 - Femoral block with dexmedtomidine reduces postoperative opioid requirement in femoral shaft fracture.
#1150 - Femoral block with dexmedtomidine reduces postoperative opioid requirement in femoral shaft fracture.

Dexmedetomidin is a novel selective α-2 adrenoreceptor agonist with anxiolytic, sedative and analgesic properties that prolongs analgesia and decreases opioid related side effects when used in perineural as a local anesthetics adjuvant. The goal of this study was to test whether it has any effect on pain intensity and opioid requirements when injected perineurally alone.This prospective and double-blind study was conducted in 60 American Society of Anesthesiologist (ASA) class I–II patients undergoing femoral fracture shafts surgery. Based on block permuted randomization, the patients were randomly divided into two groups: D and C, with and without PNB respectively.In the group D ,dexmedtomidine 100 µg, was injected to surround the femoral nerve completely using US guidance. In both groups total postoperative opioid consumption,visual analogue score (VAS) for pain were compared. There was a significant different in postoperative narcotic required in the group D in comparison to the group C. No significant adverse effects were encountered among groups. The mean VAS scores showed a significant different immediately postoperatively and at6,12and 24 hours postoperatively in the group D in comparison to the group C (< 0.05)For overall patient satisfaction, patients in the group D reported significantly higher mean satisfaction scores than those in the group C .In conclusion perineural administration of dexmedtomidine significantly decreased postoperative pain intensity in the patients undergoing femoral surgery.

 

 

 

 

 


Elham MEMARY (Tehran, Islamic Republic of Iran), Alireza MIRKHESHTI, Sadegh SHIRIAN, Ali ARHAMI, Aida KHADEMPOUR
09:10 - 10:40 #1283 - #1283 - Acute renal colic: appropriate clinical management in the emergency department ?
#1283 - Acute renal colic: appropriate clinical management in the emergency department ?

INTRODUCTION: acute renal colic (ARC) represents one of the most common causes of abdominal-lumbar pains (2.9%), and nontraumatic diagnosis (1.5 %) of emergency medical conditions. But ARC heterogenic management and inadequate analgesia are frequents. The goals of this study were (1) to evaluate emergency department (ED) practices concerning the use of analgesic drugs for optimal pain control or relief, urine diagnostic tests, and medical imaging techniques in patients with ARC; and (2) to compare this clinical assessment with national recommendations. METHODS: we performed a retrospective study of patients admitted in the ED from January 2012 to December 2013 with a final diagnosis of acute renal colic. RESULTS: during this period 440 ARC in 317patients were enrolled, of whom 213 men (71%), with an average age of 39 years. Sixty-five patients (20.5%) developed ARC recurrence (a total of 123 times) during this period. Concerning the pain intensity, 83% of patients had a score ≥ 5 on admission, using the Visual Analog Scale (VAS: 0-10) or the Numeric Rating Scale (NRS: 0-10). The meantime to pain acute care was 1 hour; but it was < 45 minutes if pain score ≥ 6. Paracetamol was the most commonly used drug for pain relief. Nonsteroidal anti-inflammatory drugs (NSAIDs), especially ketoprofen, were prescribed in 49.5% of patients. Morphine as the first choice of strong painkillers was used in only 18% of patients with pain score ≥ 8 on admission, but in 27% of them with score= 10. A NSAIDs-morphine combination therapy was prescribed as first-line drugs of choice in only 11 patients. A urine dipstick test for hematuria was negative in 20.5% of cases. A urine culture was performed in 89% of cases with positive urine dipstick test for white blood cells and/or nitrites: only 16% of them were positives. In spite of the absence of severity criteria, 73% of patients with first-episode ARC had at least one ED imaging test: sonography (42% of patients; ureteric calculi detection: 22%); noncontrast abdominal computed tomography (47%; ureteric calculi detection: 73%). Hospitalization was indicated for 74% of patients with ARC severity criteria. DISCUSSION: the application rate of ARC national recommendations was superior to 80% for almost of them. On the contrary, this rate was inferior to 70% concerning the prescription of NSAIDs (54%) and morphine (36%), and imaging indication in young people. CONCLUSION: The first priority in ARC is to ensure quick and effective relief of pain, but progress still has to be made on this matter. The respect of recommendations would improve the ARC management and diagnosis, and reduce costs and ED stay delay, critical challenges in emergency medicine. 


Paul GAYOL (Strasbourg), Samuel OUDINECHE, Eric BAYLE, Fadi KHALIL, Manana POTOCNIK, Cecile ROUSSEAU, Ruxandra COJOCARU, Benjamin LEHR, Pascal BILBAULT
09:10 - 10:40 #1408 - #1408 - Effect of local Ketamine added to Lidocaine gel on perceived pain of men during urethral catheterization.
#1408 - Effect of local Ketamine added to Lidocaine gel on perceived pain of men during urethral catheterization.

Background and Objectives

Inserting foley catheter in male urethra is one of most annoying procedures in the emergency departments. Although most of the physicians use Lidocaine gel for alleviating pain and discomfort of this procedure, there are numerous of patients who need foley catheter complaining of its pain and discomfort

This study was conducted to examine the efficacy of local ketamine along with Lidocaine gel for instillation in the male urethra for easiness of urethral catheterization, as compared with using Lidocaine gel alone.

Method

A total of seventy four male patients who were scheduled to undergo urethral catheterization were randomly assigned to receive either 10mL of 2% Lidocaine gel mixed with 1mL normal saline (Lidocaine only group), or 10mL of 2% Lidocaine gel combined with 1mL Ketamine (50mg) (Lidocaine plus Ketamine group). Up to 8 mL of prepared mixture instilled directly into the urethra. Three minutes later by using sterile and standard technique and lubricating the appropriate catheter with whatever remained from the mixture, procedure was done

Baseline characteristics and hemodynamic variables of all patients including pulse rate, respiratory rate and blood pressure were measured before and after insertion of Foley catheter. Level of pain perception of patients at the baseline and after every procedure in both groups was recorded by using the numeric rating scale (from Zero to 10).

Result

There were no significant differences in baseline characteristics and hemodynamic changes between two groups of the patients, before and after the procedure. Although pain of urethral catheterization of “Lidocaine only” group were at tolerable level (NRS= 3.8), it was significantly decreased in “Lidocaine plus Ketamine” group (NRS=1.4)

Conclusion

Instillation of Lidocaine gel in conjunction with Ketamine locally in the urethra could decrease perceived pain and would make men undergoing urethral catheterization more comfortable during the procedure. 


Amir NEJATI, Pegah LOTFABADI (Tehran, Islamic Republic of Iran), Behtash KHANIABAD
09:10 - 10:40 #1413 - #1413 - Evaluation of pain management for adult sickle cell patients in a emergency department.
#1413 - Evaluation of pain management for adult sickle cell patients in a emergency department.

Background: Pain is the main cause of presentation in an emergency department (ED) for patients with sickle cell disease. Due to the atypical presentation of those patients and the high doses of opioids needed to treat them, they are often misunderstood, under evaluated and under treated by the staff. For all those reasons we have written, in collaboration with the hematology department, a protocol including hyper-hydration and high dose of morphine.

Aims: The primary objectives were to evaluate  the management of those patients and the adequacy of this treatment with the written protocol and the pain score defined by the use of an analogic visual scale(AVS) by the patients and by the nurses. The secondary endpoints were an evaluation of the satisfaction of the patients with a questionnaire, measuring an estimated time by the patients between the first contact and the administration of the first dose of analgesic drugs and finally the total dose of opioid given.

Methods: In partnership with the department of hematology, we realized an observational prospective monocentric study, after submission to the ethical committee, concerning the treatment of adult sickle cell disease patients in our ED. This study was performed during two years (from February 2013 until February 2015) . Informed consent was obtained previously during routine visit or in the emergency department when the patients were admitted for vaso-occlusive crisis. Both nurses and patients realized a pain evaluation on admission, with AVS, and the treatment was started using the written protocol. Before leaving the ED, patients received a satisfaction questionnaire  to evaluate their degree of satisfaction. The questionnaire was graded from 1 (very bad) to 5 (very good).

Results: During this period, we registered 70679 consultations in our ED, where we recruited 104 observations (0.15%), reparsed on 51 patients. Mean waiting time was 18,6 minutes between first contact and first dose of analgesic drugs, but the received doses of morphine were significantly lower than those recommend on our protocol. The mean satisfaction score of patient was 3,8.

Discussion: Due to the presence of a protocol, we have noticed that the ED staff was more attentive and reactive to sickle cell disease patients, with a quick evaluation of the pain and a short delay between the first contact and the first dose of analgesic drugs. We also noticed a respect of the hydration program, but an underutilization of opioids,  despite the presence of a specific protocol. However, we obtained a good global satisfaction of the patients concerning their management.

Conclusion: Despite the presence of a specific protocol, we can observe that the management of vaso-occlusive crisis is quite difficult and depends on the partiality of the staff in pain evaluation and the fear to entertain a opioid addiction by those patients. The presence of a written protocol is nevertheless a good point to sensibilize the team about this quite rare affection and formations given to the staff about this rare pathology help to improve the satisfaction of the patients.


My Quyen TRAN THI, Marie Agnes AZERAD, Sana BELHAJ, Coralie CHAN, Blanche DOHET, Dr Thierry PRESEAU (Brussels, Belgium)
09:10 - 10:40 #1830 - #1830 - How to improve documentation of pain management.
#1830 - How to improve documentation of pain management.

 

RN Helle Ipsen, RN Christina Ørsted Rasmussen, RN Marianne Barylak. Emergency Department the Hospital of Nykobing Falster,

Introduction and purpose

Pain is a frequent cause leading to admission in the Emergency Department (ED,) and pain relief has importance for patient satisfaction. Surveys have shown that patient satisfaction is high, but audits in patient’s journals didn´t reflect this. Therefore, we have studied the gap between patient satisfaction, staff performance and documentation of pain management, to find the basic reason for the disagreement, which have led us to develop and implement a local guideline. The hypothesis was that the documentation only described a minor part of the efforts to treat the patient`s pain, and an altered approach to documentation of pain management would embrace the clinical efforts, and be shown in the patient files.

 

Materials and methodology

A validated semi structured questionnaire of ED nurses experience and attitude to pain management and their documentation is compared to patient satisfaction. A regional standard demands that all patients with a score > 3 on a Visual Analog Scale (VAS) have a documented plan and follow up of the effectiveness of treatment. Baseline data are results from the national investigation of patient satisfaction and standardized audit on the use of VAS in 77 cases. In the study, 20 nurses from the ED working 2 consecutive days had a questionnaire with 11 questions about how they document and perform pain treatment, and their experience of the barriers to follow the regional standards. In parallel, 20 acute patients were interviewed, and afterwards the documentation of their pain treatment was analyzed. After implementing a local guideline for pain management a follow up audit was carried out. Results are analysed with a mixed qualitative and quantitative analysis and presented as tables. 

 

Results

Baseline data: 82-87% of the patients in the ED are satisfied with the pain management, and audit shows that 85% of all patients (n=77) have been asked about pain at arrival to the ED.  Of 20 patients with a VAS > 3, audit showed less than 15% of the files contained a plan and follow up procedures for pain treatment. The nurses express a holistic approach to pain treatment using medication as well as non-pharmaceutical skills, but they experience lack of time, uncertainty about their skills in pain management and weak IT support as the main course of their insufficient documentation. Giving the nurses new opportunities to manage the patient’s pain at arrival, and instructions to use the available IT system in an easier way, the quality of documentation of pain management and follow up of the effectiveness of treatment are improved from 15% to 90%.

 

Conclusion

The study shows that the procedures nurses use to give pain relief might have importance for the patient satisfaction, although it is not demonstrated in their documentation. Giving the nurses policy options for pain management and demonstrating how to use the IT system in a simple way, can reduce the gap between documentation and the performed clinical skills.


Helle IPSEN (NYKØBING F., Denmark), Christina ØRSTED RASMUSSEN, Marianne BARYLAK
09:10 - 10:40 #1990 - #1990 - Comparison of topical lidocaine and ketamine in reducing nasogastric tube insertion pain: a double blinded randomized clinical trial.
#1990 - Comparison of topical lidocaine and ketamine in reducing nasogastric tube insertion pain: a double blinded randomized clinical trial.

Introduction: Nasogastric tube insertion is one of the routine and painful procedures in emergency department. Lidocaine gel is routinely used for analgesia before nasogastric tube insertion. There are growing evidences on local effect of sub anesthesia doses of ketamine in reducing procedures pain without developing systemic effects. This study was designed and performed for comparison of routine nasogastric tube insertion with lidocaine and nasogastric tube insertion using ketamine.

Methods: This prospective double blinded randomized clinical trial was performed on emergency department's patients who were above 18 and without serious concurrent disease. Patients were divided into two groups. We administered 3ml (50mg) intranasal ketamine 5minutes before nasogastric tube insertion in one group and other group patients just received 3ml of distilled water in the same way. Nasogastric tube insertion was done by using lubricant gel in former and lidocaine 2% gel in latter group.

Results: Seventy four patients were enrolled in the study (equally distributed). There were not any significant differences between demographic data in two groups. Pain was significantly lower in ketamine group (visual analogue scale: 38.162 ± 8.398 vs. 57.417 ± 11.193); however there was not any significant difference on difficulty of tube insertion (mean 5 point Likert scale: 2.879 ± 0.451 vs. 2.680 ± 0.500). Complications were nearly same in two groups.

Conclusion: Nasogastric tube insertion using intranasal ketamine produces less pain than using intranasal lidocaine. Ketamine is a safe drug for nasogastric tube insertion in patients without serious concurrent illness. However, nasogastric tube insertion using ketamine is no way easier than insertion using lidocaine.


Arash SAFAIE (Tehran, Islamic Republic of Iran), Amir NEJATI, Reza SHARIAT MOHARARI, Ali ARDALAN, Seyedeh Roghieh LARIMI
09:10 - 10:40 #914 - #914 - Oral ketamine versus oral midazolam for sedation of children during laceration repair.
#914 - Oral ketamine versus oral midazolam for sedation of children during laceration repair.

Background: Children referred to the pediatric emergency department  for suturing a laceration often require sedation in order to lower anxiety and  pain and to induce amnesia.

Objective: To assess the efficacy of oral Ketamine vs oral Midazolam for sedation in laceration repair at the pediatric emergency department

Methods: Children aged 1-10 years with  laceration requiring suturing were recruited at the pediatric emergency department. After obtaining consent from the legal guardian, children were randomly assigned using a computer-generated sequence to one of two groups. One group was treated with oral ketamine 5 mg/kg (maximal dose 70 mg)  and the other was treated with oral midazolam 0.7mg/kg (maximal dose 20 mg). Parents and investigators were blinded to randomization until statistical analysis of the study was completed.

Main outcome measures were level of pain during local anesthesia, as assessed by VAS (visual analog scale) by the parent, and the number of children who failed oral  sedation. Secondary outcomes were VAS by investigator, level of sedation using the UMSS (University of Michigan Sedation Scale), parents and physician satisfaction, length of stay and adverse effects.

The analysis of the data was done by intention to treat and per protocol. Groups were compared  by t-test or Mann Whitney for continuous variables and by Fisher exact test  for categorical variables. The estimated sample size was 26 children in each group.

Results: Eighty six eligible patients were approached and  68 children were recruited. Thirty seven children were allocated for treatment with Ketamine and 31 for Midazolam. Mean age was 5.6 + 2.1 years in children treated with ketamine and 4.5 + 2.1 years in children treated with midazolam (mean difference 1.1, 95% CI 0.05 to 2.1).There were no other differences between groups in the demographic characteristics. Failure to achieve adequate sedation was more common among children treated with ketamine. Twelve (32% ) of the children treated with ketamine required IV sedation compared with only two children (6%) of the children treated with midazolam (p=0.014). Twenty five children treated with ketamine and 29 children treated with midazolam completed the study. VAS by a parent during local anesthesia was 4.8 +3.3  in children treated with ketamine and 3.8 +3 in children treated with midazolam (mean difference 0.96, 95% CI -0.74 to 2.67). Average UMSS in children treated with ketamine and midazolam was  1.6+0.84 and 1.7+0.65  respectively. Average recovery time was 105.08+29.09 minutes in children treated with midazolam  and 98.78+30.63 in children treated with ketamine. There was no significant difference between groups in the physician satisfaction from the procedure  as assessed on VAS.  No serious adverse effects were noted.

Conclusions: In children requiring sedation for laceration repair treatment with 5mg/kg of oral ketamine compared with 0.7mg/kg of oral midazolam resulted in higher proportion of sedation failure. In the doses tested, oral midazolam provide better sedation.


Orit RUBINSTEIN, Shiri BARKAN, Rachel BRITEBRAT, Sofi BERKOVITCH, Michal TOLEDANO, Natali KARADI, Anat NASSI, Eran KOZER (Zerifin, Israel)

11:10
11:10-12:40
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A22
State of the Art
Pulmonary Emergencies

State of the Art
Pulmonary Emergencies

Moderators: Barbra BACKUS (Emergency Physician) (Rotterdam, The Netherlands), Said LARIBI (PU-PH, chef de pôle) (Tours, France)
11:10 - 11:40 Assessment of suspected venous thromboembolism in 2015. Franck VERSCHUREN (MD, PhD) (Presenter, Brussels, Belgium)
11:40 - 12:10 V&A in the ED: A blood gas masterclass. Anne-Maree KELLY (PHYSICIAN) (Presenter, Melbourne, Australia)
12:10 - 12:40 Non-invasive ventilation in the ED. Roberto COSENTINI (Head of Emergency Medicine) (Presenter, BERGAMO, Italy)

11:10-12:40
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B22
Italy invites
La Sofferenza in pronto Soccorso

Italy invites
La Sofferenza in pronto Soccorso

Moderators: Agostino GERACI (Italy), Mario GUARINO (NAPLES, Italy)
11:10 - 11:30 Il dolore acuto in pronto Soccorso: riusciremo a gestirlo adeguatamente? Fabio DE IACO (Chief) (Presenter, Imperia, Italy)
11:30 - 11:50 Il dolore nel fine vita: progetto SIMEU per le cure palliative. Alessio BERTINI (Presenter, Pisa, Italy)
11:50 - 12:10 Comunicare le cattive notizie: il contenimento della sofferenza. Roberto RECUPERO (Presenter, Cirie, Italy)
12:10 - 12:30 La cura del "dolore" : quali ripercussioni sull' equipe di PS ? Carla OLIVETTI (Presenter, Italy)

11:10-12:40
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C22
Clinical Questions: Controversies
Neurological Emergencies

Clinical Questions: Controversies
Neurological Emergencies

Moderators: Giancarlo AGNELLI (Milano, Italy), Martin WIESE (Consultant) (Leicester)
11:10 - 11:40 How and where should TIA patients be evaluated? Andy JAGODA (Presenter, USA)
838:5 - 12:10 Which patients with acute headache should be imaged? Vincent BOUNES (CHEF DE SERVICE) (Presenter, Toulouse, France)
12:10 - 12:40 Which patients with back pain need emergent MRI? Jonathan EDLOW (Presenter, USA)

11:10-12:40
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E22
Research
Cardiovascular Emergencies

Research
Cardiovascular Emergencies

Moderators: Pr Rick BODY (Professor of Emergency Medicine) (Manchester), Eric REVUE (Chef de Service) (Paris, France)
11:10 - 11:40 Do we need another hero? Tomorrow's cardiac biomarkers. Pr Rick BODY (Professor of Emergency Medicine) (Presenter, Manchester)
11:40 - 12:10 Aortic Catastrophes. Rob ROGERS (Presenter, USA)
12:10 - 12:40 Advances in the pre-hospital diagnosis of acute coronary syndromes. Jacob SORENSEN (Presenter, Denmark)

11:10-12:40
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F22
YEDM
Sim Wars

YEDM
Sim Wars

Moderators: Pier Luigi INGRASSIA (Lugano, Swaziland), François LECOMTE (PH) (Paris, France)
Coordinators: Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Coordinator, Besançon, France), Youri YORDANOV (Médecin) (Coordinator, Paris, France)

11:10-12:40
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G22
Paediatric Track
Paediatric Infectious Disease

Paediatric Track
Paediatric Infectious Disease

Moderators: Ian MACONOCHIE (United Kingdom), Pr Hezi WAISMAN (Director, Dept. of Emergency Medicine) (Petach-Tikva, Israel)
11:10 - 11:40 Paediatric Infectious Disease. Javier BENITO FERNANDEZ (DIRECTOR) (Presenter, BILBAO, Spain)
11:40 - 12:10 Sport and Exercise Medicine in the Paediatric ED. Dr Thomas BEATTIE (Senior lecturer) (Presenter, Edinburgh, United Kingdom)
12:10 - 12:40 Panel discussion.

11:10-12:40
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OP1-22
Oral Paper 1
Management / ED Organisation I

Oral Paper 1
Management / ED Organisation I

Moderators: Lars Petter BJORNSEN (Emergency Physician) (Trondheim, Norway), Susan ROBINSON (Doctor) (Cambridge, UK, United Kingdom)
11:10 - 12:40 #1107 - #1107 - An experienced nurse as Flow Processing Manager in the Emergency Department to overcome overcrowding-related risks.
#1107 - An experienced nurse as Flow Processing Manager in the Emergency Department to overcome overcrowding-related risks.

INTRODUCTION / BACKGROUND

Emergency Departments (EDs) are struggling with crowding and its associated morbidity, mortality, and decreased patient and health-care worker satisfaction

In an era of ED overcrowding, an efficient triage system is essential because it allows the emergency team to treat patients according to the urgency of their condition

 

AIMS, MATERIALS / METHODS

A triage liaison provider may be a way to improve ED throughput, when additional staff resources are available, in an effort to improve patient satisfaction, decrease waiting time (WT), improve clinical care and decrease lost revenue from patients leaving without treatment.

A senior experienced nurse, with known both technical and non-technical skills, was added in the ED, during daily shifts (h 8-14 and 14-20) in working days, acting after the usual nurse triage protocol, and before the Medical Doctor (MD) taking charge of the patient.

His tasks, as a Flow Processing Manager (FPM), were:

- to upgrade triage evaluation process and improve throughput efficiency in a timely manner,

- to early identify time-dependent situations (by clinical or welfare conditions) and outliers,

- to redirect and address (according to the instant picture of the ED) the specific patient (according to his acuteness, frailty and complexity), to a specific route (according to the need for less or more intensive care), and to a specific MD (according to his expertise, and being more or less busy).

We performed a prospective “before and after” cohort study, in the ED of a University Teaching Hospital, from 08/4/2012 to 07/4/2013, and from 08/4/2013 to 7/4/2014, to assess the impact of FPM in terms of WT, rate of outliers, patients Left Without being Seen (LWS), and MD performances.

 

RESULTS

We compared “before” (control group) and “after” (intervention group) data (respectively):

the number of triaged patients augmented (67400 “before” versus 70922 “after”);

waiting times (media; in minutes.seconds) slightly changed depending on “triage code” (red 7.04 versus 7.02; yellow 15.32 vs 21.25, green 84.10 vs 88.07, white 88.55 vs 78.04);

total time spent in the ED (media; in minutes) dramatically changed depending on “triage code” (red 221 versus 940; yellow 988 vs 1159, green 218 vs 699, white 161 vs 177);

the number of patients admitted slightly increased (24687 versus 24759);

LWS rate decreased (1135 versus 741).

 

CONCLUSIONS

In the ED the introduction of an additional experienced nurse provider as FPM showed the ability to ameliorate patient throughput, waiting times and LWS rates, improving both safety and quality of care, even coping with the dramatic increase in length of staying due to overcrowding and shortage of beds.

ED waiting rooms are high liability areas for hospitals: opposite to trends towards overall increasing risks, the addiction of a FPM can actually reduce risks in individual patients

 


Chiara LANZARINI, Dr Rodolfo FERRARI (Bologna, Italy), Sauro CANOVI, Gianni VITALE, Mario CAVAZZA
11:10 - 12:40 #1134 - #1134 - Critically ill patients in the shock room: We must improve !
#1134 - Critically ill patients in the shock room: We must improve !

Introduction: patients in the resuscitate room (or shock room) are considered the most critically ill patients and correspond to 4-5% of vital distresses in an ED according to literature. Our main objective is to optimize its use and thus provide a better quality of care.

Materials and Methods: A retrospective comparative analysis of patients treated in the shock room during 3 years (2012-2014) in a General Hospital ED since the implementation of a 24 hours/day dedicated resuscitate Team composed by the prehospital EMT (senior Emergency Physician, nurse and nurse aide). Patients’ demographic data, diagnoses and outcomes were accessed. Comparison of patients chief complaints to Nurse and Physician Triage, analyze of Waiting Time (WT), Length of Stay (LOS).

Results: In the last 3 years among 41000 visits / year in the ED, the absolute rates of emergency room utilization rose, the rate of unstable patients demanding urgent intensive care regularly increase with a mean number of 445 patients / year (4% of all admissions) in 2014. Sex Ratio 60 Male /40 % Female. Average age 62.7 years. Most important activity on Monday 16.5% vs 11.5% on Saturday, hourly peak 11-12 AM 7.1% vs 3% 9 / 10am activity increased in winter 34.6% vs 27.5% in summer. Neuro-vascular disorders (18%) multiple trauma (15.6%) and respiratory distress 12.4% . Before their admission in the ED, 39 % of patients were managed by prehospital EMS . A majority of these patients had severe Triage level (1-2) but 52% of patients were initially in the general ED ward and not in the shock room. The LOS in the resuscitate room is 2 hours for 66% of patients and remains stable despite the increasing activity of ED visits. Patients were oriented to the intensive care unit (31%), Observation Unit (26%) or transferred (10%) in other centers.

Discussion: our study highlights essential points for the initial triage and the impact of a LOS on morbidity /mortality for critically ill patients .Optimal management of the shock room with regular training of multidisciplinary medical team to determine whether subjects need immediate admission to the shock room. Risk management precautions dictate that under no circumstances would an unstable patient remain in the open triage section of the emergency room under inferior surveillance and need to stay immediately in the shock room. A new protocol with the Triage Team is in progress to evaluate the impact on the management of the shock room.

Conclusion: management of the shock room is an important part of the treatment chain of the severely injured patients in the Emergency Department. Successful management in the resuscitate room requires a reliable and effective tailored guidelines for evaluation and decision protocol of Triage and regular evaluation of patients in the ED.


Eric REVUE, Alexandre HENNIART (Agen), Akim SADDAR, Perrine MEGRET, Delphine CASENAVE, Melinda PERCHERON
11:10 - 12:40 #1444 - #1444 - A New Model of Urgent Care Centre in the Emergency Department of the United Kingdom.
#1444 - A New Model of Urgent Care Centre in the Emergency Department of the United Kingdom.

A New Model of Urgent Care Centre in the

Emergency Departments of the United Kingdom

 

Abstract

 

Introduction:  Primary Care patients in the accident and emergency departments have been the topic of discussion since 1998 in the United Kingdom.  Numerous studies have analysed attendances retrospectively and suggest that at least one third to two thirds of patients attending the emergency department with problems which could be managed appropriately in General Practice.  The pattern of emergency department usage seems to be international.  Outside the United Kingdom in Australia and many departments in the United States include walk in facilities.  Staffed by Physicians on family practice residency programme.  It clearly appears in the United Kingdom that emergency departments have to accept that such patients with primary care problems will attend the emergency department and facilities will have to be provided to provided services to these patients. 

 

Urgent care centres were developed near the accident and emergency departments to reduce the pressure on the emergency departments.  Unfortunately this has not happened.  It has been noticed that when more patients are seen in Urgent Care Centres the number of attendances in emergency departments increase as well. 

 

Objective:  We started a new model of Urgent care centres where the urgent care centre was located in the emergency department and is staffed by a General Practitioner and a Senior Doctor in the department.

 

Method:  We studied the number of patients, type of patients and the time it took for the patients to be seen in the Urgent Care Centre. 

 

Results:  Our Urgent Care Centre has been running for the last six months and we have seen a gradual increase in the number of patients being seen from 6.89% to 46.85% now.  Most of these patients were in the category 4 and 5 according to the Manchester Triage System. 

 

Discussion:  It has been recognised that primary care patients in the Emergency Department are a major part of attendances of the Department and unless the patients are seen in Urgent Care Centres, overcrowding and long waits in the Emergency Department could not be avoided.  It has been shown that employing Primary Care Physicians in the Emergency Department reduce the costs of Emergency Departments because Primary Care Physicians do not carry out as many investigations as by the junior doctors in the Emergency Department and the number of admissions are reduced as well.

 

Conclusion:  None of the patients had to wait for more than two hours to be seen in the Urgent Care Centre and we feel that the care provided to the patients by the Urgent Care Centre is highly effective, reduces costs and is satisfying for the patient.


Mohammad ANSARI (Solihull, United Kingdom), David FOROUGHI, Ahmed ISMAIL, Aslam R TABANI, Muhammad ARFAN
11:10 - 12:40 #1482 - #1482 - The impact of ramadan on emergency department attendances in a tertiary care hospital of middle east.
#1482 - The impact of ramadan on emergency department attendances in a tertiary care hospital of middle east.

Background:

Emergency Department (ED) patient attendances have an inherent variability during certain periods of the day and month to month1. Predictability of this pattern helps in planning adequate staffing ratios and allocating resources. During the month of Fasting (Ramadan), healthy adult Muslims do not eat or drink from dawn to dusk2. During this month, in the Middle East, there is a significant change in the sleep-wake pattern of the society3.  It is not known, if these social and cultural factors affect the ED attendance pattern.

Objectives:

This is a retrospective study of ED patient attendance variability in the day and night shift during Ramadan, in a tertiary care hospital of a country with a predominantly Muslim population. This will improve understanding of patient presentation patterns and will assist managers to align resources with the patient care presentation.

Method:

The data was retrieved from the Hospital’s integrated clinical information system (ICIS). All ED visits during the Islamic calendar year of 1432 (December 7, 2010 - November 25, 2011) were included. Direct admissions to the hospital are excluded. Descriptive statistics for the continuous variables are reported as mean± standard deviation and categorical variables are summarized as frequencies and percentages. Continuous variables are compared by Student’s independent t-test or ANOVA as appropriate; while categorical variables are compared by Chi-square test. The level of statistical significance is set at p<0.05. The statistical analysis of data was done by using the software package SAS version 9.3 (Statistical Analysis System).

Result:

A total of 58,859 patients presented to ED, 33,602 (57.09%) were during the day shift (0700 to 1900 hrs.) and 25,257(42.91%) during the night shift (1901 to 0659 hrs.). A total of 50,470 patients (85.75%) were discharged home and 5,142 (8.73%) were admitted to the hospital. Average monthly patient visits during the day were 2,800 (57%) and 2,105 (42%) during the night shift. There was a statistically significant difference in the arrival time of the patients during Ramadan and the attendance pattern was reversed; 1614 (39%) patient during the day and 2,568 (61%) during the night shift (p<0.0001) (Table 1). However, there was no statistical difference in patient admissions and discharges (p>0.1).

Conclusion:

ED patient attendance pattern changed during Ramadan with greater number of patients presenting during the night. Therefore, allocation of resources in ED of tertiary care Hospitals of predominantly Muslim populations, should match the nocturnal arrival pattern of the patients.


Taimur BUTT (Riyadh, Saudi Arabia), Israr AHMED, Abdelmoneim ELDALI, Hameed Ullah KHAN
11:10 - 12:40 #1494 - #1494 - CEM books- A facebook for emergency department.
#1494 - CEM books- A facebook for emergency department.

I am Dr Anantha Nag Kadiyala, an Emergency medicine Consultant working in United Kingdom at Bradford Royal Infirmary. I would like to present this excellent software tool which would benefit Emergency departments to maintain and monitor safety. College of Emergency Medicine (CEM) books is a suite of mobile & web applications designed by NHS consultants and managers being used in emergency departments (ED) to better understand the demands on their systems, share information and make intelligent informed decisions. Users quickly enter logs and situation reports with live metrics of personalised performance indicators. These are analysed to give an overall visual status of a department and predict performance. Status and issues are escalated to key individuals able to enact immediate responses. In app access to key documents, phone numbers and web links promotes real time consistent adherence to current trust policies.

 

Features: 

1. Situation Reports: Structured assessments of your department’s key performance indicators could be quickly entered to create a comprehensive understanding of departmental status.

 

2. Handover: Capture departmental handovers in an accessible, retrievable and searchable format. It uses the Royal College approved ABCDE handover structure with added personalised features specific to the department.

 

3. Log Book: Quickly enter structured situation, background, assessment & recommendation (SBAR) logs detailing important events and interactions. This would help sharing the experiences and difficulties by the staff working in the department. These logs can be tagged to categorise and identify the themes targeting important issues.

 

4. Escalation & Sharing: Relevant Information is escalated vertically and shared horizontally across the organisation allowing team members to see and respond in real time.

 

5. Analysis: Key Performance Indicators could be visualised by hour, day, week & month. Recurrent themes could be searched by using tags. The status of the Emergency department could be divided into three categories (red, amber and green) depending on the safety. For e.g. Indicators of emergency department of Bradford Royal Infirmary are as follows.

  1. Patient Vs doctor ratio
  2. Ambulance hand over time
  3. Time to triage 
  4. Capacity of resuscitation room, paediatric, majors and minors cubicles
  5. Average time to see a patient in each area of the department 
  6. Number of senior doctors, Nursing staff
  7. Number of patients awaiting beds
  8. Specialist review time in ED

 

6. Notifications: Notifications can be sent as in app push messages, emails or text messages. Notifications could be tailored according to the personal need.

 

7. Feedback: Staff requested friends and family feedback ensures local ownership and control. Feedback is anonymously linked to staff members, teams, and live departmental performance. Paper and administration free system promotes personal, team and business values.

 

8. Rule Book: Immediate access to all relevant departmental documents. Built in governance structure to ensure only approved current guidance with clear ownership & expiration dates will be available.

 

9. Phone Book: Immediate access to all relevant departmental phone numbers. It foregoes the need for landlines and calls to switchboard operators. Personalised favourites lists could be created if necessary.

 


Anantha Nag KADIYALA (Bradford, United Kingdom), Brad WILSON
11:10 - 12:40 #1507 - #1507 - Capacity modelling of an emergency department observation unit by discrete event modelling.
#1507 - Capacity modelling of an emergency department observation unit by discrete event modelling.

April 2015 we have moved to a new emergency department (ED) with less treating positions while there is a steady increase in the yearly number of patients.  Because in the former ED we were already facing flow problems with an increasing length of stays (LOS) we decided to change policies in order to accelerate flow in the ED and between the ED and the hospital.  A previous study showed that the introduction of an observation unit (OU) could help to guarantee patient flow in the ED. Therefore a 30-bed OU is deployed in the new hospital.  The aim of this preparatory study was to estimate the required number of beds in the OU. The number of beds needed was calculated by discrete event simulation using Arena Software (Rockwell Software). The model maps the patient flow in the ED and between the ED and hospital wards like the OU. Input in the model were admission pattern, interval times for clinical, diagnostic and therapeutic ED interventions, LOS in both the ED and the hospital of a representative sample of 4734 patients, admitted to the ED between October, 1st 2012 and September, 30th 2013. The model allows to estimate the number of observational beds needed for several scenarios. In all scenarios, it was assumed that all patients first are transferred to the OU before they eventually are admitted to another hospital ward, except for 33% of the patients in need of special care  like intensive care, obstetrics, psychiatry or paediatrics. Another basic rule was a maximal LOS in the OU of 48h. In order to get a grip on the capacity range of the OU, we introduced different what-if scenarios with variability in the LOS of the ED and the OU. For the ED the values for LOS were not truncated (no maximum) or truncated at a maximum of 8h, 6h and 4h in four different scenarios. For the OU the maximal LOS was 48u but the peak of the triangle distribution of LOS was set at 24, 30 or 36h. Combination of different scenarios for the LOS at the two levels of the ED and the OU induce differences in the needed capacity of  the OU. The results of the study show that the P75 of required bed positions in the OU range between 26 (no maximal LOS in ED combined with peak LOS in OU of 24h) and 34 (LOS in ED maximal 4h, peak LOS in the OU of 36h). Discrete event simulation, if based on a representative database, allows to map patient flow revealing bottlenecks and to perform what-if scenarios for capacity without disturbing the real life practice.  This approach helps to choose the best  scenario to optimize  the  patient flow in the future ED to the OU with 30 positions. The model shows that the OU cannot handle all admitted ED patients and therefore some ED patients will still have to be admitted directly at the correct hospitalisation ward bypassing the OU.


 


Diederik VAN SASSENBROECK (Ghent, Belgium), Tim DEBACKER, Paul GEMMEL, Paul CALLE
11:10 - 12:40 #1594 - #1594 - A protocol-driven organisation in Observation Units Services reduces admission and increases appropriateness: an Italian comparative study.
#1594 - A protocol-driven organisation in Observation Units Services reduces admission and increases appropriateness: an Italian comparative study.

 Background

 The health care reform of the last years in Italy brought to a significant reduction of hospital beds for acute admission and the Emergency Departments (ED) have to intervene on the organisation of more structured Observation Units (OU) in order to observe and treat patients with a high probability of early discharge, who need a management longer than 6 hours (limit for a simple ED visit). In general, the maximum length of day in the OU is 30 hours.

In many regions of Italy the OUs have been structured with dedicated beds and organised with specific protocols for some pathological conditions. In the Piedmont region such protocols have some defined outcome indicators, previously established and reviewed periodically. In other regions such process is in progress and specific protocols are not yet available.

Methods

In this study we have compared the performance of the EDs of two secondary hospitals: the first, in Piedmont region (S. Andrea hospital, Vercelli), with a structured OU and defined protocols and the second, in Marche region (S. Lucia Hospital, Macerata), without a structured OU. We have focused the attention in the management of 4 specific conditions-atrial fibrillation (AF), hypoglycaemia, epilepsy/seizures, head injury-to assess the adherence to such indicators. The results of Macerata hospital have been evaluated according to the indicators of Vercelli.

Results

In Vercelli hospital the ED visits were 30348 from January to December 2013; the overall admission rate was 12.5% of the admissions; 3893 pts were kept in the OU (12,8%) and among them 751 were admitted after the observation period (18,8%).

In Macerata hospital the 2013 ED visits were 29686 and the overall admission rate was 20.2%; 1451 patients were kept in the OU (4,89%) and the admissions were 596 (41,1%).

The mean length of stay in the OUs was around 18 hours in both hospitals.

The outcome indicators for the 4 protocols considered were: AF <5% admissions, Hypoglycaemia <10% admissions, Epilepsy/seizures <30% admissions, head trauma 100% CT scan in anti coagulated patients.

All the outcome indicators have been respected by the Vercelli OU, while the admission rate for AF in Macerata was 14%, for Hypoglycaemia 60%, for Epilepsy 46%. The head trauma indicator was met in both hospitals

Conclusions

A structured OU allows to increase the number of patients observed and to decrease the total number of admissions, improving the appropriateness with a rational use of hospital beds.

The presence of specific protocols allows to better categorize patients and to evaluate the appropriateness of the interventions according to the relative outcome indicators.


Aldo TUA, Barbara GABRIELLI (VERCELLI, Italy), Roberta PETRINO, Tamara MARIANI, Domenico BORRUSO, Michele SALVATORI, Roberta TERRIBILE

11:10-12:40
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OP2-22
Oral Paper 2
Pre-hospital and transportation

Oral Paper 2
Pre-hospital and transportation

Moderators: Joost BIERENS (Thesis Coordinator EMDM) (Brussel, Belgium), Gregor PROSEN (EM Consultant) (MARIBOR, Slovenia)
11:10 - 12:40 #1063 - #1063 - From chest-pain onset to the angioplasty, observation of delays in different stages of pre-hospital management of acute coronary syndrome with ST-segment elevation: prospective study.
#1063 - From chest-pain onset to the angioplasty, observation of delays in different stages of pre-hospital management of acute coronary syndrome with ST-segment elevation: prospective study.

Introduction: In the strategy of ST-segment elevation myocardial infarction (STEMI) management, response time of a mobile intensive care unit (MICU) may be influenced by urban population density, and accessibility to the catheterization laboratory (cath-lab).

Objective: Evaluate delays in STEMI management, for each stage, from onset chest-pain to the catheterization.

Method: Data derived from a prospective register including non-complicated STEMI having primary percutaneous coronary intervention (PCI), managed by 6 medical care intensive units (MICU) of a French city: 3 in town (T) and 3 in suburb (S). The observed variables were the place of management (T or S), the time delays of the various stages: time delay from chest-pain onset to the first medical contact (FMC) by the patient to the pre-hospital despatching emergency medical service – time delay FMC to MICU arrival – cath-lab door (cath-lab) – needle – catheterization (KT). We compared delays between MICU T and S using the Wilcowon test (p value < 0,05).

Results: In 2012, 137 STEMI have been included, T= 62 (45%), S= 75 (55%). Charts reports time delays of various stages. Global median time delays of management were T= 113 [110; 130] min vs S= 112 [101; 125] min (p= 0.8906). Median time delays from the 15-call to FMC were T= 20 [13; 35] min vs S= 22 [14; 36.5] min (p=0.4122) with a higher dispersion for the MICU S. Median time delays from FMC to the cath-lab were T= 49.5 [40.3; 60] min vs S= 53 [45.3; 61.8] min (p= 0.1365) with a higher dispersion for the MICU T in this case. The MICU did not influence anymore the time delays of management since they have confided the patient to the cath-lab team. Median time delays from the cath-Lab to needle were T= 20 [10; 30] min vs S= 19 [11.5; 26] min (p= 0.8546). Finally, median delays needle to KT were T= 13.5 [7.5; 15] min vs S= 13 [10; 20] min (p= 0.2707). By stage, there was no significant statistical difference for a patient managed by a MICU in suburb or in town. The MICU S came later but took less time to dispatch the patient to cath-lab.

Discussion: the distribution of cath-lab more scattered in suburb, but more easily accessible that in town does not seem to influence time delays of management by the MICU, and thus doesn’t affect the management of STEMI patients. There is therefore no loss of opportunity for a patient in our region managed by a MICU in town or in suburb respectively. Other factors must be studied on a more important sample of patients.


Hugues LEFORT (Marseille), Alain COURTIOL, Aurélie LOYEAU, Laurence SZTULMAN, Yann-Laurent VIOLIN, Amandine ABRIAT, Jonathan GONZVA, Olivier YAVARI-SARTAKHTI, Isabelle KLEIN, Michel BIGNAND, Jean-Pierre TOURTIER
11:10 - 12:40 #1083 - #1083 - A prospective registry: best performance for prehospital reperfusion decisions in case of high volume of managed ST-segment elevation myocardial infarction (STEMI)?
#1083 - A prospective registry: best performance for prehospital reperfusion decisions in case of high volume of managed ST-segment elevation myocardial infarction (STEMI)?

Introduction: Amount of reperfusion therapy (primary percutaneous coronary intervention (pPCI) or fibrinolysis) performed is a determinant of mortality in STEMI patients. The decision to propose reperfusion therapy is a cornerstone of STEMI patient management in the pre-hospital setting, and the 2012 European Society of Cardiology guidelines suggest that the frequency of reperfusion decisions represents a marker of quality of care.

Objective: To determine whether the number of STEMI managed by Mobile Intensive Care Units (MICU) and Emergency Medical System services (SAMU: Service d'Aide Médicale Urgente) is a determinant of the frequency of prehospital reperfusion decisions. 

Methods: The eMust registry was set-up by the regional health authority of the 12-million-population of Paris region in France to prospectively collect data on all STEMI patients transported by the physician-staffed SAMU ambulances. The registry has been ongoing since 2003 and all data gathered up till 2013 were used for the present analysis. Emergency physicians from MICU initiate treatment in the prehospital setting and take the initial decision of reperfusion (primary PCI or fibrinolysis).  Results were statistically significant if p< 0.05.

Results: During the 11-year study period, 18,294 STEMI patients were included by 8 SAMU and 41 MICU were dispatched on site. The mean number of STEMI managed by each SAMU was 2,287, with a minimum of 139 and a maximum of 300; and a mean number of those managed by each MICU of 457 with a minimum of 7 to a maximum of 152 inclusive. Decisions made by each MICU to send the patients for reperfusion therapy ranged from 73% to 97%. Total decisions were pPCI: 76% and fibrinolysis: 24%. Decisions by each SAMU to send the patients for reperfusion therapy ranged from 90% to 95%. There was a significant difference in the frequency of reperfusion decision between SAMU and MICU (Chi2 test, p < 0.0001) in the region, between 2003 and 2013: 18% of prehospital thrombolysis, 74% of direct referral to the Cath Lab, 7% of non-decision.  However, this frequency of decision was not correlated (R= 0.1264) to the volume of managed STEMI (SAMU or SMUR) without being significant (T-distribution, p= 0.4371).


Gilles LENOIR, Jonathan GONZVA, Hugues LEFORT (Marseille), Yves LAMBERT, Aurélie LOYEAU, Nicolas DANCHIN, Thévy BOCHE, François DUPAS, Sophie BATAILLE, Frédéric LAPOSTOLLE
11:10 - 12:40 #1146 - #1146 - Presence of Staphylococcus aureus and Enterococcus in Danish ambulances. A cross-sectional study.
#1146 - Presence of Staphylococcus aureus and Enterococcus in Danish ambulances. A cross-sectional study.

Background

Every year approximately one out of ten Danish patients contract an healthcare associated infection (HAI). Staphylococcus aureus and Enterococcus are, among others, known as prominent in the group of pathogenic bacteria that underlies HAI, causing the patients unnecessary genes and prolonging their hospitalization. Bacterial colonization often occurs due to indirect patient-to-patient transmission, caused by poor hygiene complience. This study aimed to determine the level of contamination with S. aureus/MRSA and Enterococcus/VRE on pre-cleaned blood pressure cuffs in the Danish medical service. This study is conducted in cooperation with the "Emergency Medical Services, Capital Region of Denmark", Copenhagen Fire Brigade and Frederiksberg Fire Brigade.

Method

In the Capital Region of Denmark, 50 blood pressure cuffs from 39 different ambulances were tested for S. aureus and Enterococcus in this cross-sectional pilot study. Prints were collected using specific agar plates, no earlier than one minute after cleaning with Ethanol wipes. Furthermore, positive prints were typed and determined of resistance.

Results

Both S. aureus and Enterococcus were present on pre-cleaned blood pressure cuffs however, to a limited extent. The average level of contamination by S. aureus was 0.54 CFU per 25 cm2 (SD 1.98). Minimum and maximum values were ranging from 0 to 11 CFU per 25 cm2 and the prevalence of 50 prints were 10%.  The average level of contamination by Enterococcus was 0.06 CFU per 25 cm2 (SD 0.42). Minimum and maximum values were ranging from 0 to 3 CFU per 25 cm2 and the prevalence of 50 prints were 2%. The positive Enterococcus isolate belonged to Enterococcus faecalis, and showed no resistant genes. All S. aureus isolates were methicillin sensitive S. aureus (MSSA).

Conclusion

Potentially pathogenic bacteria are detectable on equipment thought to be clean. However, none of the detected bacteria showed resistant properties, which could indicate a low rate in the prehospital setting. The findings of pathogens after cleaning may be due to cross-contamination, improper cleaning or limited effect of the cleaning procedure. Therefore, a thorough examination of the contamination level, effect of different cleaning procedures as well as increased focus on hygiene challenges in the prehospital setting is recommended. 


Heidi Storm VIKKE (Kolding, Denmark), Matthias GIEBNER
11:10 - 12:40 #1202 - #1202 - Using of LUCAS II device for CPR by regional no-urban Medical Emergency Service.
#1202 - Using of LUCAS II device for CPR by regional no-urban Medical Emergency Service.

Background: LUCAS II was developed for automatic chest compressions during cardiopulmonary resuscitation (CPR). Current evidence on the use of this device in out-of-hospital cardiac arrest (OHCA) is still insufficient.

Purpose: The aim of this study was to compare the effect of CPR for OHCA with and without LUCAS by Regional non-urban Emergency Medical Service (EMS) in physician-present pre-hospital medical system (randes-vous system).

Methods: We analyzed a prospective registry of all consecutive OHCA patients in four EMS stations, two of them used LUCAS device in all CPR, the EMS crews in other two stations used manual CPR. Individuals with contraindication to LUCAS or with EMS-witnessed arrest were excluded.


Results: From May 2010 to June 2014 337 patients were included in the OHCA registry. Fifty-nine patients were excluded from the analysis because of contraindications to LUCAS or EMS-witnessed arrest. Data from 278 patients were included in the analysis, 144 with LUCAS and 134 with manual CPR.
We observed more witnessed arrests in LUCAS group (64,18% vs. 79,17%,p=0,0074) and more asystoly as initial rhythm in LUCAS group (48,51% vs. 69,44%,p=0,0004). We did not find significant differences in return of spontaneous circulation (ROSC) between the groups (30,6% in nonLUCAS vs. 25% in LUCAS, p=0,35), in ROSC in arrests of cardiac etiology (31,25% vs. in non LUCAS vs. 24,18% in LUCAS, p=0,31) and in ROCS if initial rhythm was ventricular fibrillation (51,43% in nonLUCAS vs. 46,43% in LUCAS, p=0,80). In LUCAS group we observed significant more conversions from non-shockable to shockable rhythm (10,10% vs. 20,7%, p=0,0396). 180 days follow up was provided by in patients (85% of patients with ROSC in both groups). We observed significant more survivors in nonLUCAS group (p=0,0198). We did not find any survival difference in arrests of presumed cardiac etiology (p=0,3175).
 
Conclusions: The use of automated chest compressions with LUCAS system in our study did not improve survival rate in OHCA. We observed significantly higher 180-days mortality in LUCAS treated patients by regional non-urban EMS.


Jiri KARASEK (Prague, Czech Republic), Rostislav POLASEK, Alena RECHOVA, František KLEIN, Petr OSTADAL
11:10 - 12:40 #1242 - #1242 - Telemedicine consultation with physician at the emergency medical center from ambulances enables emergency medical technicians to treat-and-leave more patients – a before and after pilot study.
#1242 - Telemedicine consultation with physician at the emergency medical center from ambulances enables emergency medical technicians to treat-and-leave more patients – a before and after pilot study.

 

Background / introduction

Ambulance dispatch is the first step on the path of treatment of acutely ill patients. Changing the course of this path affects all parts of the health care system involved in emergency patient care.

In this pilot-study we manned the Emergency Medical Dispatch Center (EMDC), Aarhus, 24/7 with physicians experienced in emergency care.  All non-critically ill patients (category B&C) in the Central Denmark Region who called 1-1-2 and received an ambulance were given telemedicine assessment by the EMDC physician. The purpose of the assessment was to treat-and-leave if judged safe.

 

Participants and methods

Trial design: Controlled before and after study

Intervention:  Systematic prehospital teleconsultation from ambulances to EMDC physician 24/365 15-28 September 2014.

Control:         Fraction of patients treated and left 16-29 September 2013 without telemedicine assessment.

Participants:  All non-critically ill patients in the Central Denmark Region who called 1-1-2 and received an ambulance.

Outcome measures:

  1. Fraction of non-critically iLl patients treated and left.

          Statistics: chi2

  1. Safety of telemedicine based treat-and-leave.
  • Rate of treated-and-left patients admitted to hospital within three days
  • 30 day mortality

      Statistics: chi2

 

Results

  1. Patients treated and left.

          In 2013 641 non-critically ill 1-1-2 patients received an ambulance compared to 774 in 2014. The fraction of patients being treated and left was 0.3320 in 2014 (257 patients) and 0.2605 in 2013               (167 patients) giving an OR=1.410, 95%CI [1.112, 1.791], P=0.0035. In total 125 patients were treated-and-left after telemedicine assessment by EMDC physician.

  1. Safety. Data analysis is ongoing.

 

Discussion/conclusion

The fraction of non-critically ill 1-1-2 patients treated and left after telemedicine assessment is surprisingly high.

This could indicate an unused potential for the EMDC physician in the prehospital patient care and that the EMDC physician may play a more active part in the care of emergency patients in the future.

Safety evaluation awaits.

 

Acknowledgements

The study war partly funded by the Prehospital Emergency Medical Services, Aarhus, Central Denmark Region.

 


Nikolaj RAABER (Aarhus, Denmark), Ingunn RIDDERVOLD, Morten BOETKER, Niels-Christian EMMERTSEN, Hans KIRKEGAARD
11:10 - 12:40 #1276 - #1276 - Pulmonary oedema: is morphine still indicated?
#1276 - Pulmonary oedema: is morphine still indicated?

Pulmonary oedema:  is morphine still indicated?

 

Paul Slavu(1), Sorina Podariu(1), Corina Sintea(1), Vlad Fisca(2), Daniela Taran(2), Mirela Badescu(2), Iris Muresan (3)

1. Emergency department, SMURD Sibiu, Sibiu, Romania

2. Emergency department, UPU-SMURD Sibiu, Sibiu, Romania

3. Lecturer, "Lucian Blaga" University of Sibiu, Romania

 

Speaker: Sorina Podariu

 

Keywords: acute pulmonary oedema, morphine, protocols

 

BACKGROUND

 

During the last three years, SMURD (Mobile Emergency Service for Resuscitation and Extrication) Sibiu MICU was sent to an important number of cardiac related cases reported as shortness of breath, mostly during night time.

 

Although shortness of breath can be associated with several illnesses, one life threatening condition is acute pulmonary oedema.  Without proper and prompt medical care, survival chances are greatly decreased. Although it may have other underlying causes, in the majority of cases it originates from heart conditions, especially left ventricle insufficiency. The commonly used distinction between cardiogenic, non-cardiogenic and of unknown causes is used to describe the affection as accurately as possible.

 

 

The aim of this study is to asses a proper path of treatment by relying on internationally accepted protocols while drawing from the knowledge of extensive practical experience. The study focuses on presenting our observation that by including morphine in the treatment of pulmonary oedema, SMURD Sibiu frequently sees a faster and easier recovery of patients. Using only diuretics and nitrates does not have the same rate of success.

 

This practice is regulated by current protocols that limit the use of morphine. Concerns are expressed by some physicians about the possible risk that it might present to the patient, including an increase in the risk of death after discharge from hospital. As a result, alternative medication is sometimes considered.

 

METHODS

 

This study is retrospective and it is based on the SMURD (Mobile Emergency Service for Resuscitation and Extrication) Sibiu database accumulated over a period of 3 years, from 2012 to 2014. It includes 101 cases of acute pulmonary oedema.

 

RESULTS

 

From a total number of 101 patients with acute pulmonary oedema, 51 were treated with morphine, 78 cases happened during the night, 33 between 8 am in 8 pm.

While following the results of the administrated treatment, when including morphine 38 patients have improved and 12 patients had persisting symptoms.  When using only diuretics and nitrates, 27 patients have improved and 23 patients persisted with symptoms.

 

Out of these, 9 patients suffered cardiac arrest on the way to the hospital, and 2 of them deceased, although CPR and ALS were performed.

 

 

 

CONCLUSIONS

 

Assessment of our data suggested that morphine administration enhances even more chanches of our patients, proving they recover easier, comparing the use of diuretics and nitroglycerin only. Even more, morphine can be administrated when the use of nitrates and diuretics must be postponed due to haemodynamic instability.


Paul SLAVU, Daniela TARAN, Sorina PODARIU (, Romania), Corina SINTEA, Vlad FISCA, Mirela BADESCU, Iris MURESAN
11:10 - 12:40 #1369 - #1369 - Dispatcher-Assisted Cardiopulmonary Resuscitation Program and Outcomes after Pediatric Out-of-hospital Cardiac Arrest.
#1369 - Dispatcher-Assisted Cardiopulmonary Resuscitation Program and Outcomes after Pediatric Out-of-hospital Cardiac Arrest.

Background : The dispatcher-assisted bystander cardiopulmonary resuscitation (DA-BCPR) is expected to influence the outcomes of pediatric out-of-hospital cardiac arrest (OHCA).

Objective: We investigated and compared the association and the effect size of DA-CPR on survival outcomes according to location of the event.

Methods: All EMS-treated OHCAs less than 19 years of age in Korea were analyzed from January, 2012 through December, 2013, excluding patients witnessed by EMS providers or missing outcome information. Exposure group were No-BCPR group for patients who did not receive BCPR, BCPR-NDA group for patients who received BCPR without DA, and BCPR-DA for patients who received DA-BCPR. The endpoint was survival to discharge. Multivariable logistic regression analysis was performed to calculate the adjusted odds ratios (AORs) and 95 % confidence intervals (CIs) for outcomes by exposure group (reference=No-BCPR group) with and without an interaction term between exposure and location of arrest.

Results: A total of 1,013 eligible patients were finally analyzed. Among these patients, 39.8% had received BCPR (16.6% BCPR-NDA and 23.2% BCPR-DA). The survival to discharge rate was significantly higher in BCBP-NDA (10.7%) and BCPR-DA (9.0%) compared with No-BCPR group (4.3%) (p=0.002). AORs (95% CI) for survival to discharge compared with No-BCPR group were 1.73 (1.03-3.12) in BCPR group, 1.71 (0.85-3.46) in BCPR-NDA, and 1.39 (0.72-2.69) in BCPR-DA group, respectively. The AORs (95% CI) of BCPR-NDA and BCPR-DA in public location were 3.30 (1.12-9.72) and 2.95 (1.00-8.67) while BCPR-NDA and BCPR-DA in private location were 1.62 (0.68-3.88) and 1.15 (0.53-2.51), respectively.

Conclusion: The DA-CPR was associated with better outcomes in pediatric OHCA patients whose arrest occurred in public location, but not in private location. 


Yu Jin LEE (SEOUL, Republic of Korea), Sang Do SHIN, Seung Chul LEE, Kyoung Jun SONG, Eui Jung LEE, Young Sun RO, Ki Ok AHN
11:10 - 12:40 #1508 - #1508 - Adverse events during inter-hospital transportation of critically ill patients: A prospective analysis.
#1508 - Adverse events during inter-hospital transportation of critically ill patients: A prospective analysis.

Objective. To assess the quality and quantity of adverse events during physician- and nurse-led inter-hospital transfers and to define transport characteristics that could be linked to an increased rate of adverse events.

Methods. Prospective observational study with case-control design in 2 hospitals in Belgium, one tertiary and one secondary referral centre with registration of patient and transport characteristics during inter-hospital transfers. Overall adverse events (OAE) were categorized as technical, operational and communication problems. Retrospectively labelled medical adverse events (MAE) and prospectively registered harmful adverse events (HAE) were documented for every transfer. All reported OAE were retrospectively appraised by the investigators for being a high-risk transport (HRT).

Patients: 688 adult patients who were transferred to or from both hospitals by physician or nurse led transport with complete registration forms.

Results. The mean age was 64,4 (SD 16,8) with a 4:3 male/female ratio. Mean M-SOFA score was 3,0/20, resp. 4,6/20 and 2,4/20 for hospital 1 and 2. Average transfer time was 45 min (SD 32 min).

OAE were present in 16,9% of transfers, with 3,9% MAE and 1,3% bringing patient harm. 3,7 % was judged to be a HRT. 1 patient died during pre-transport stabilisation.

In multivariate analysis, two factors remain significantly associated with an increased risk of HAE: operational problems (odds ratio, 16.889; P=0.001) and communication problems (odds ratio, 7.165; P=0.01). Technical problems, nurse lead transportations, duration of the transportation, and the M-SOFA score were not significantly associated with the risk of HAE.

Conclusion. The rate of adverse events is comparable or lower to what was found in the scarce literature on incidence of adverse events during inter-hospital transfers, depending on definition.  Operational problems and communication problems are the two categories that are significantly associated with an increase of harmful adverse events. These findings call for stricter preparation of transfers, both for training of personnel and communication. Extensive and repeated training is paramount to reduce the number of MAE and harm. Clear and standardized communication is important to reduce harm, and will also increase efficiency. 


Dr Cathelijne LYPHOUT (Ghent, Belgium), Duchatelet CHRISTOPHE, Jochen BERGS, Koen DESCHILDER, Willem STOCKMAN, Koen BRONSELAER
11:10 - 12:40 #1535 - #1535 - Prehospital or in-hospital administration of ticagrelor to open coronary artery in acute myocardial infarct with st-segment elevation (stemi). Atlantic study.
#1535 - Prehospital or in-hospital administration of ticagrelor to open coronary artery in acute myocardial infarct with st-segment elevation (stemi). Atlantic study.

Background: The direct-acting platelet P2Y12 receptor antagonist ticagrelor can reduce the incidence of major adverse cardiovascular events in patients with STEMI.

Goal: Evaluate if prehospital administration of ticagrelor improves coronary reperfusion and clinical outcome.

Methods: International, multicenter, randomized, double-blind study involving patients with ongoing STEMI of less than 6 hours duration, comparing prehospital (in the ambulance) versus in-hospital (in the catheterization laboratory) treatment strategy. In the prehospital group, patient received a 180 mg loading dose of ticagrelor before transfer and a matching placebo in the catheterization laboratory. All patients subsequently received ticagrelor at a dose of 90 mg twice daily for 30 days.

Coprimary end points: proportion of patients who did not have a 70% or greater resolution of ST-segment elevation before percutaneous coronary intervention (PCI) and proportion of patients who did not meet the criteria for TIMI flow grade 3 in the infarct-related artery at initial angiography.  

Secondary end points: included the composite of death, myocardial infarction, stent thrombosis, stroke, or urgent revascularization at 30 days.

Safety end points: included major or minor bleeding but excluding bleeding related to coronary-artery bypass grafting (CABG), within the first 48 hours and over the 30-days treatment period.

Results: During two years (Sept. 2011- Oct. 2013), 1862 patients were enrolled and randomized by 102 ambulances of 13 countries over 4 continents. 909 patients received ticagrelor in the ambulance and 953 patients in one of the 112 PCI centers. The medium times from symptom onset to STEMI diagnosis, from randomization to angiography, and between the two loading doses (i.e., prehospital vs. in-hospital) were 73, 48, and 31 minutes, respectively. More than 95% of the patients received one of the two loading doses of the medication study and more than 99% received at least one dose of aspirin. The majority of patients with STEMI received maintenance treatment of ticagrelor (86%) and aspirin (92%).

For all the patients included, the median time between onset of symptoms and PCI was 159 minutes.

There was no significant difference between the prehospital and in-hospital groups in terms of the proportion of patients who did not have a 70% or greater resolution of ST-elevation before PCI, nor those who did not have a TIMI flow of grade 3 in the infarct-related artery at initial angiography.

There was no significant difference between the two groups for the composite end point of death, bleeding events, major cardiovascular events or stent thrombosis. However, definite stent thrombosis was reduced in the prehospital group both at 24 hours (p=0.008) than at 30 days (p=0.02), vs in-hospital group.

Rates of composite major and minor bleeding events that were not related to CABG, were low at each stage of the study and did not differ significantly between the two groups.

Conclusion: The present study shows that the administration of the potent P2Y12 receptor antagonist ticagrelor shortly before PCI does not improve reperfusion of the culprit artery before the procedure but is safe and may prevent post-procedural acute stent thrombosis.


Olivier STIBBE (Paris), Pascal DANG-MINH, Hugues LEFORT, Olga MAURIN, Catherine RIVET, Jennifer CULOMA, Gilles MONTALESCOT, Jean-Pierre TOURTIER, Frédéric LAPOSTOLLE
11:10 - 12:40 #1634 - #1634 - Non-Invasive ventilation in acute pulmonary edema. Does it have immediate clinical effects in prehospital setting?.
#1634 - Non-Invasive ventilation in acute pulmonary edema. Does it have immediate clinical effects in prehospital setting?.

Introduction: Non-Invasive ventilation (NIV) is an adjuvant treatment for Acute Pulmonary Edema (APE). Early treatment with NIV could be applied in the prehospital setting if it demonstrated symptoms improvement in a shorter time.

Aim: To analyze if time to get to an optimal oxygen saturation and respiratory rate, shortens when NIV is added to standard medical treatment, instead of using high concentration oxygen mask.

Methods: A cohort’s prospective non-matched observational study was performed. Patients with suspected APE (confirmed at hospital arrival), treated either with NIV or with high concentration oxygen mask, plus standard medical treatment by Advanced Life Support Units from the Pre-hospital Emergency Medical System of the city of Barcelona between 1st October 2013 and 31th January 2014 were included. Time to get to oxygen saturation over 95% and a respiratory rate under 30 respirations per minute was analyzed with a survival analysis (Kaplan Meier and multivariate Cox regression), adjusting by possible confounders.

Results: 103 patients with APE were included. 56,3% were females and the mean age was 79,7 (SD:9,6) years old. NIV was applied in 44,7% of the patients during a mean of 51 (SD:13,4) minutes. Oxygen saturation improved over 95% in a median of 12 minutes (CI95%: 9,5-14,5) when NIV was applied, opposite to a median of 37 minutes (CI95%:30-44) when oxygen mask was applied (Log Rank p<0,001). Time to get to respiratory rate under 30 respirations per minute shortened from 57 minutes (CI95%:41,6-78,3) when oxygen mask was applied to 36 minutes (CI95%:31,1-40,9) when NIV was applied (Log. Rank p=0,002).

After adjusting results by Systolic blood pressure, first measured oxygen saturation and initial respiratory rate, oxygen saturation over 95% enhancement ratio significantly improves when NIV is applied; HR=5,32 (CI95%:2,8-10; p<0,001).  Respiratory rate enhancement ratio after adjusting by previous ischemic heart disease, initial respiratory rate and complete medical administration also improves significantly; HR=2,54 (CI95%:1,4-4,7; p=0,014).

Conclusions: NIV shortens time to improve oxygen saturation and respiratory rate when applied in patients suffering an APE. Further studies are needed to confirm this results and to know if NIV has effect over other parameters such as respiratory effort or the subjective feeling of dyspnea. 


Silvia SOLÀ-MUÑOZ, Francesc CARMONA-JIMÉNEZ (Barcelona, Spain), Àngels LÓPEZ-CANELA, Jorge MORALES-ÁLVAREZ, Xavier ESCALADA-ROIG, Quim RIOS-SAMBERNARDO
11:10 - 12:40 #1712 - #1712 - Five years of experience providing prehospital emergency medical service in centralized organizational model.
#1712 - Five years of experience providing prehospital emergency medical service in centralized organizational model.

The World Health Organization regards emergency medical service (EMS) system as an integral part of any effective and functional health care system. In order to improve EMS provision in Latvia a major change in organization of prehospital EMS was made in 2009. Before 2009 prehospital emergency medical care (EMC) in Latvia was provided through decentralized organization model. Latvia had overall 43 institutions owned by municipalities which provided EMS within municipality’s service area only. Lack of accessibility, quality and equity in EMC provision was evident and large discrepancies throughout the country in terms of training, staffing and coverage of the ground ambulance system existed. In 2009 gradual merging of EMC providers and reorganization of two public institutions (incl. Center of Disaster Medicine) was initiated. Although the merge was complex and complicated process on 1st of July, 2010 unified State Emergency Medical Service (SEMS) started to provide prehospital EMC in all the territory of Latvia.  The aim of the reform was to improve quality and equal accessibility of prehospital EMC by introducing unified management system of resources, centralization of incoming calls and dispatching, provision of unified standards for equipment and medicines, development of unified guidelines and unified training system. Centralization resulted in development of common regulations what lead to unified EMC delivery. Differences in EMC availability due to patient location were diminished and EMC provision was more equal than ever. In 2010 Operational Management center was established and direct number ‘113’ for medical emergencies was introduced. Outcomes of centralized EMC provision includes cost effectiveness, transparent expenditures of State budget, unified information and quality management system, electronic database of medical records and unified administration. The average response time interval for highest priority cases in rural and urban areas was diminished from 19,8 / 10,4 min in 2009 to 18,3 / 10,1 min in 2014. Many experts, including World Bank, have recognized prehospital EMS reform in Latvia as one of the most successful examples in health care organization.


Ilze BECA (Riga, Latvia), Renate PUPELE, Liega ZALCMANE
11:10 - 12:40 #1743 - #1743 - Evacuation of severely burned patients by HEMS.
#1743 - Evacuation of severely burned patients by HEMS.

Objectives: The aim of this work is to analyse the procedures of dealing with patients with burns applied by the HEMS teams both in terms of rescue operations and transporting patients from hospitals to Burn Centres.

Materials: Between 2011 and 2014 the Polish Helicopter Emergency Medical Service (Lotnicze Pogotowie Ratunkowe) executed 1347 interventions involving victims of burns. Direct flights to the location of an incident accounted for 59.8% and the remaining 40.2% were transports of patients from hospitals to Burn Centres. In the period subject to analysis those flights constituted 4.2% of all missions of the Polish Helicopter Emergency Medical Service.

Results: In the analysed group of patients, based on the International Classification of Diseases, Tenth Revision, the largest group (48.6%) consisted of persons with thermal burns of multiple body regions, 14% of patients had burns on 60-80% of Total Body Surface, and 2.9% were diagnosed with respiratory tract burn injuries.

The median duration of the mission from notification to delivery of the injured was 77 minutes in case of flights to accident location (which indicates that the HEMS teams apply the sty and play strategy) and 165 minutes in case of transporting patients from hospitals to Burn Centres.

Among the transported patients 347 (25.7%) were subjected to endotracheal intubation and 85.6% of all intubations applied to patients prepared for transportation from hospitals to Burn Centres. Crystalloid intravenous infusions and pain therapy were applied as treatment of 99.1% of all patients. During the missions 0.4% patients had cardiac arrest and were resuscitated.

Conclusions: The use of HEMS in case of dealing with patients with burns is of material importance in providing quick transport to Burn Centres, specifically in case of childrens with burns. 

A significant part of interventions involved the “stay and play” strategy.

 

The procedures of preparing patients for helicopter transportation involved protecting the airways with substitute ventilation which related to over one fourth of all patients.

 


Przemyslaw Wiktor GUŁA (Krakow, Poland), Robert GAŁĄZKOWSKI, Arkadiusz WEJNARSKI
11:10 - 12:40 #1791 - #1791 - Optimization of EMS design. Advanced vs Basic.
#1791 - Optimization of EMS design. Advanced vs Basic.

Objective: Polish EMS model is based on Advanced Life Support Ambulances (partially with physicians partially with ALS trained paramedics). However only less then 5% of total  number of interventions require advanced life saving procedures.  The current model does not allow for optimal use o emergency physicians in prehospital settings. 

It requires guidelines for building new double tier (advanced/basic) response system.

Material and methods: Retrospective analysis of  43437 EMS interventions during one year period in mixed city-country terrain.  17 EMS teams (5 with physician) located in 13 ambulance sattions with single (999) dispatch centre covered the population of over 576 000 people. The number of calls was 10,9  per 100 inhabitants.

Results: Almost 60,7% calls to the local dispatch (999)  centre lead to the dispatching of EMS team.  72,5% of  interventions were the ALS-paramedic teams  and 27,5 % were responded by emergency - physician ambulances. The median response time  was 6,5 min in the city and 10,5 min in country.  In more then 30% of the EMS interventions there were no medical emergencies. 66,7% of patients were transported to the ED. Advanced life saving procedures allowed to physicians only amounted to 1,5% of cases. In the phyician ambulances group 32,7% of patients had iv line ,32,7% followed by intarvenous drug administration. 3,8% of patients were intubated.  Paramedics requested support of physician or HEMS amounted to less then 1% of missions.

Conclusions: The Polish EMS system is highly abused by unfounded requests. It must be optimised in terms of function of double tier response as well as flexible use of emergency physicians in prehospital area. 

 

 


Przemyslaw Wiktor GUŁA (Krakow, Poland), Robert GAŁĄZKOWSKI, Remigiusz MORYTO
11:10 - 12:40 #1802 - #1802 - NonSTEMI Prehospital RisK Score.
#1802 - NonSTEMI Prehospital RisK Score.

INTRODUCTION:

Ischaemic heart disease is the first cause of death in developed countries. For several years it has been demonstrated that patients suffering from Acute Coronary Syndrome (ACS) with persistent ST elevation (STEMI), benefit of primary angioplasty (PCI), directly making the transfer from the point of first medical contact to the cardiac catheterization laboratory. For patients with Non-ST-Segment Acute Coronary Syndrome  (Non-STEMI) several risk SCOREs have being developed. The gold Standart is GRACE SCORE. However, these Scores are designed for the hospital environment, which represents a delay in shipments of a subgroup of patients to centers of high specialization.

The aim of this study is to create a predictive ability model of prehospital risk SCORE for patients suffering NSTEMI in order to transfer them to the appropriate hospital.

Objective:

Define and create a prehospital emergency care Scale for predicting high risk cardiovascular events comparable to GRACE SCORE in NSTEMI, that allows the transfer of the patient to the appropriate Center.

Methods:

Prospective cohort study, of patients admitted to the Coronary Care Unit of a Tertiary Hospital during the period from January 2009 to December 2013 in Barcelona.

Inclusion criteria: patients over 18 years old with a diagnosis of NSTEMI for whom GRACE has been calculated.

The recruitment was carried out consecutively.

Study variables: GRACE at admission, sex, age, cardiovascular risk factors, history of ischemic heart disease, vital signs, ECG abnormalities, presence of complications.

Descriptive and comparative analysis. Patients were stratified into high risk and not high risk (low and medium risk), according to GRACE Score and were compared to the new Scale. A predictive model was obtained using logistic regression and the selected variables were compared with high risk of GRACE using the Spearman rank correlation coefficient and Kappa statistic. The efficiency of the model was  assessed with a ROC curve.

 

Results:

420 patients were included, 72.6% of them were men with a median age of 67,4 years. 149 (35,5%) patients had a high-risk Grace, 271 (64.5%) had low or moderate risk Grace.

The new Scale is composed of 6 items, scored from 0 to 11 points, and  high risk is defined over 5 points. These items are: age, Killip-Kimball, Systolic blood pressure, Heart Rate, ST desviation ≥ 0.5mm  and previous angina. The new Scale compared with binary Grace (high risk/not high risk)  showed a Spearman correlation= 0.78 and a Kappa=0.79. Sensitivity was 90.8% and specificity 89.9%, Likehood ratio (LR+)=7.5, positive predictive value (PPV)=93,2%, negative predictive value (NPV) =84% and a global efficiency of 89.8%. The area under the curve (AUC) of the estimated model was 0,893, 95% interval confidence (0, 86-0, 93).

Conclusions:

1 - The new Score predicts patients comparable with high risk GRACE Score that should be transferred to a hospital with PCI available 24 hours 365 days.

2 – The Score can be a pre-hospital tool to determine the target center for patients with High-Risk Non-STEMI.


Jorge Arnulfo MORALES ALVAREZ (Barcelona, Spain)
11:10 - 12:40 #1829 - #1829 - Early Exclusion of Major Adverse Cardiac Events in Emergency Department Patients with Chest Pain: a prospective observational study.
#1829 - Early Exclusion of Major Adverse Cardiac Events in Emergency Department Patients with Chest Pain: a prospective observational study.

BackgroundIn the management of adult chest pain patients presenting to an Emergency Department (ED) with suspected acute coronary  syndrome (ACS), we aimed firstly to validate diagnostic accuracy of a modified Thrombolysis in Myocardial Infarction (TIMI) score with high-sensitive cardiac troponin T (hs-cTnT) to rule out major adverse cardiac events (MACE), and secondly to compare modified TIMI score with combinations of heart-type fatty acid binding protein (H-FABP) and a modified HEART score.

 

Methods  This prospective observational study was conducted in the ED of a university hospital in Hong Kong, recruiting patients aged 18 years or older with chest pain and suspected ACS.  Patients underwent triage assessment, electrocardiography, blood sampling for laboratory hs-cTnT, H-FABP point of care test, and TIMI and HEART scoring.

 

Results  602 consecutive patients were recruited and MACE occurred in 42 (7.0%) patients within 30 days. A modified TIMI score of zero alone identified 65 (11%) patients, and a HEART score ≤2 identified 96 (16%) patients, as having low risk for 30-day MACE.  No MACE occurred in these groups giving both scores a sensitivity and negative predictive value of 100%, and respectively a specificity of 11.6% and 17.1%.  Use of both TIMI and HEART scores improved specificity further to 22.0%. Early H-FABP had a sensitivity of 42% and a specificity of 91%.

 

Conclusions  A modified TIMI score of zero or a HEART score of ≤2, incorporating a single hs-cTnT level, will identify patients with low risk of 30-day MACE for early discharge within 2 hours of ED arrival.

 


Colin GRAHAM (Hong Kong, Hong Kong), Cw LAM, Kh CHEUNG, Yk LEUNG, Nm CHENG, Py CHAN, Timothy RAINER
11:10 - 12:40 #1936 - #1936 - Patient characteristics in pre-hospital medical care. Is there a difference in between physician and non-physician dispatched patients?
#1936 - Patient characteristics in pre-hospital medical care. Is there a difference in between physician and non-physician dispatched patients?

Background

In Germany an increasing number of patients in emergency departments (ED) are presented by ambulance services. National studies investigating the pre-hospital emergency services are rare. A particularity in the emergency care in Germany is the distinction between paramedic-staffed ambulances and physician-staffed ambulances. The purpose of this study was to examine the difference between physician and non-physician dispatched patients.

Methods

This explorative study includes patients who were dispatched by ambulance services in the internal or surgical ED at Charité Virchow-Klinikum in Berlin, providing maximum medical care. Routinely available data were retrieved from ambulance protocols for every patient admitted via ambulance between Mai 1st until June 30th 2014. The ambulance protocols provide information on date and time of ambulance service, demographic details, vital parameters, injuries, intensity of pain as well as diagnostic and therapeutic procedures. They were matched with data from the hospital information system (e.g. Manchester-Triage-System category (MTS), in-hospital mortality). Patients were excluded, if the distinction between paramedic-staffed ambulances and physician-staffed ambulances was not raised in the data. All analyses were stratified for ambulance services with and without physician.

Results

In total 1070 datasets were analyzed (median age 53 years, IQR 35-71; female 46%). 62% were medical ED-patients, 36% surgical and 2% neurological. Physicians were included in 30% (n=322) of all ambulance transports with the highest proportion in patients between 70 and 79 years (18%).

The majority of emergency missions for the study population were registered on Mondays (18%) and the minority on Wednesdays (12%). The majority of physician-staffed ambulance transports was on Mondays (21%) and the minority on Fridays (11%). Within a day emergency services were most frequently called between 12am and 6pm (29%). Nearly two third of all emergency missions took place at private apartments (59%). 18% of all missions were conducted in public areas. Ambulance transport from general practitioners and nursing homes to the ED were observed in a proportion of 3% and 4% respectively.

The urgency of treatment was documented in five categories for 789 patients by pre-hospital emergency staff. 7% of the cases were classified as non-urgent and 45% as normal. A higher proportion of physician-assisted ambulances vs. paramedic-staffed ambulances was associated with cases which were classified as urgent (48%vs32%), as very urgent (21%vs5%) and as life-threatening (9%vs1%). Similar results could be seen in the ED´s with a higher proportion of physician dispatched patients in the orange (45%vs22%) and the red (19%vs2%) MTS-level. In contrast, the proportion was lower in the yellow MTS-level (30%vs52%) as well as in the green and blue MTS-levels. No difference could be found in the length of stay (median 4 days). The in-hospital mortality was higher in patients which were dispatched by physician-assisted ambulances (6%vs3%).

Conclusion

The majority of ambulance transports was conducted on Mondays. Physician-staffed ambulances were more involved in older patients and cases with urgent conditions. This finding was underlined by the higher in-hospital mortality of patients in this group. Further analyses will address clinical course and pre-hospital procedures.


Johann FRICK (Berlin, Germany), Anna SLAGMAN, Julia SEARLE, Clara THOMAS, Judith MAHLIG, Tobias LINDNER, Pr Martin MÖCKEL
11:10 - 12:40 #1985 - #1985 - Out-of-hospital use of laryngeal tube - a large observentional study.
#1985 - Out-of-hospital use of laryngeal tube - a large observentional study.

Introduction

Because of concerns of low success rate and unidentified oesophageal intubation of orotracheal intubation in the prehospital settings, supraglottic devices have received widespread acceptance in emergency medical systems. There are more devices on the market and there is still need for a larger evaluation of these devices in relation to their reliability and safety. In this large observational study we prospectively evaluated the effectiveness and safety of use of the laryngeal tube (LT-D) by trained physicians and paramedics in prehospital airway management in two periods.

Methods

In 2009 we started to train all paramedics and physicians in the largest Slovak EMS provider Falck Zachranna in insertion and management of LT-D. In the company there is no strict protocol for securing the airways and some physicians do not intubate regularly. The participants who demonstrated the ability to ventilate a manikin effectively with a bag through correctly inserted LT-D were given competence to use it clinically. The quality and safety of the process was monitored by mandatory filling of the protocol after every placement of LT-D. We have recorded demographic data, indications, paramedics vs physicians insertions, difficulties in placement, complications and rate of successful ventilation. We have compared the safety and effectiveness data of LT-D from two periods - 2009-2011 and 2012-2014.

Results

In the years 2009-2014 a total of 152, 228, 424, 504, 512 and 614 LT-Ds have been used. In the first period we evaluated 804 and in the second period 1630 protocols. In both periods 82% of tubes have been inserted by paramedics and 18% by physicians. The rate of male has been stable at around 65%. The main reason for insertion was in 74% and 77%, resp. cardiovascular failure (mostly cardiac arrest). LT-D has been replaced by endotracheal intubation in 28% and 23%, resp. (physician based ambulance has been called). The ventilation was not possible in 6.8% and 5.1% resp.; that means success rate of 93.2% and 95.1%, resp. Aspiration before or after insertion has been observed in 2.7% and 4.0%, resp. Insertion has been considered easy in 75% and 78%, resp.

Discussion

This is to our knowledge by far the largest study with LT-D in pre-hospital settings evaluating 2,436 LT-D insertions. Most participants reported that handing of the LT-D was easy and they only required three insertion practice sessions with a manikin to feel confident. The tube was mostly used by paramedics who are not allowed to intubate in Slovakia. We encouraged physician not to replace well placed LT-D by paramedics by intubation and have observed decreasing rate of it. We have also recorded small increase in success rate and stable rate of aspiration during the observation period.

Conclusions

In this large study we confirmed previous evidence that LT-D is easy to handle with a high success rate of the placement. The LT-D replacing bag and mask ventilation frees the hand of paramedics, helps to safely secure airways for non-emergency physicians and helps to secure difficult/failed airways for anaesthesiologists and emergency physicians in prehospital care.

 

 

 


Stefan TRENKLER (Košice, Slovakia), Monika PAULIKOVA, Miroslav HUMAJ
11:10 - 12:40 #2041 - #2041 - Are there alternatives to acute hospitalization for elderly medical patients? - a randomised clinical trial.
#2041 - Are there alternatives to acute hospitalization for elderly medical patients? - a randomised clinical trial.

Introduction: The Danish public healthcare service to elderly patients with acute medical conditions is uncoordinated. The General Practitioner (GP) is responsible for the patient but is challenged by difficult communications with other healthcare sectors and has a busy workday often without the ability to see the patient immediately. Short admissions, as well as the risk of loss of information at the transfer from secondary to primary sector, may result in sub-optimal diagnosis and treatment pathways, especially for elderly patients with complex medical issues. The municipalities have implemented initiatives to ensure an alternative to hospitalization, but this acute municipal care did not focus specifically on cross-sectorial collaboration and has not been evaluated. The aim of the project was to evaluate various cross-sectorial collaborations with focus on elderly medical patients: I) How many medically ill elderly will use an acute municipal care as an alternative to hospitalization, and what are their characteristics? II) Is there a difference if a medical specialist at the hospital is responsible for the examination and treatment instead of the GP? III) Is there a difference between treatment at a municipal acute care centre and home treatment from an acute care team?

Method: The project design was a randomized clinical trial in which the primary outcome was the number of admissions within 7 days, depending on whether a medical specialist or the GP was responsible for the treatment. Simultaneously, mortality, mental and physical changes as well as the satisfaction of the patient and relatives were registered as secondary outcomes. The collected data were also used to assess the impact of treatment from municipal acute care centre or acute care team on the same outcomes.

Results: 131 patients were included. The patients were predominantly women of high age with daily need of help at home. By triage assessment, the included patients were rated as ill as the average hospitalised patients. Half of the patients was able to take care of themselves after 48 hours of treatment, and about a quarter needed extra help at home or an extended stay at the care centre. Men were hospitalised twice as often as women.

Half of the patients examined by the hospital’s medical specialists were admitted immediately, while only a quarter of the patients examined by the GP were admitted. There were no significant difference in mortality, physical or mental restoration between the patients treated by the medical specialist and the GP, but the low number of participants may have hidden real differences. There was no significant difference in the numbers of admissions in the two municipal acute care, and there was no difference in how quickly patients recovered mentally and physically or in mortality and satisfaction.

Conclusion: The acute care team and acute care centre offers an equally good treatment. A hospital based outpatient clinic appears to increase the number of acute admissions of elderly medical patients. It can therefore be concluded, that the cooperation between GP and municipal acute care can reduce the number of admission of elderly medical patients.


Helene SKJOET-ARKIL (Aabenraa, Denmark), Christian Backer MOGENSEN
11:10 - 12:40 #2075 - #2075 - Croatian Index of Emergency call Admission in Recognizing Out of Hospital cardiac arrest(OHCA).
#2075 - Croatian Index of Emergency call Admission in Recognizing Out of Hospital cardiac arrest(OHCA).

Croatian Index of Emergency Call Admission in Recognizing Out of Hospital Cardiac Arrest

Radmila Majhen Ujevic, MD, Leo Luetic, MD

Key words: Index, Medical Dispatch Unit, OHCA, recognize, red response, agonal, training, education

Introduction: Medical Dispatch Unit (MDU) is essential part of the chain of survival and enables rapid and accurate medical response in case of OHCA. Recognition of OHCA is achieved on criteria based dispatch in the form of Croatian Index of emergency call admission, which has bee used in Croatia for three years. We made a survey to see how accuurate Index was in predicting OHCA in Split-Dalmatian County which has cca 455000 inhabitants.

Methods: quantitative analysis of data collected in one-year period. We compared cases of OHCA noted in our registry of deaths ( EMS confirmed arrest in the field), as dioagnosis R96-R99 ( Ill-defined and unnown causes of mortality according to International Classification of Disease ICD) and I46 ( cardiac arrest) to the criteria in Index during call receipt. Citeria considering possible OHCA were A01.01 ( Adult unconscious, not breathing) and all other criteria fulfilling the condition " does not respond to shaking and calling". deaths caused by trauma, other external factors, terminal disease with expecting death as well as children were excluded from the survey.

Results: there were 945 cases where EMS confirmed cardiac arrest caused by medical problems in the field. In the group of 618 calls ( 65,40%) admitted as red response, 276 calls (44,66%) were orrectly presumed to be OHCA. In the group of 321 calls (34,34%) admitted as yellow response, 112 calls (34,89%) were correctly presumed to be OHCA ( H criteria concerning definitive, irreversible expected death). In 6 calls (0,97%) dispatched as green response there were 3 calls (50%) accureately presumed to be OHCA. In the group of red response there were 82 calls (13,27%) admitted and dispatched as criteria A01.03 ( person unconscious, but breathing) that EMS pronounced as cardiac arrest in the field.

Conclusion: More training in MDU through re-listening of incoing calls and reassessmentof criteria ( finding out which criteria are mostly used instead of A.01.01) is needed in intention to improve OHCA recognition. This is particularly important in recognizing agonal breathing, not to be misjudged as normal breathing that might delay quick beginning of CPR. However, the benefit of patients was not jeopardised since they have received red response. More research might be needed in comparing response times in presumed OHCA and cases assessed like other red response, but not OHCA ( core item in Utstein Style Report). Recent possibility of recording procedures like CPR phone instructions by dispatcher enables further research in improvent of chain of survival ( early recognition and early CPR). Important factor contributing this aim are public programmes of education in basic life support/AED in community.


Radmila MAJHEN UJEVIC, Radmila MAJHEN UJEVIC (yes, Croatia), Leo LUETIC

14:10
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A23
Management
Education

Management
Education

Moderators: Pier Luigi INGRASSIA (Lugano, Swaziland), Rob ROGERS (USA)
14:10 - 14:40 The future of medical education. Chris NICKSON (Presenter, South Yarra, Australia)
14:40 - 15:10 Medutainment: Is this the way to teach Emergency Medicine? Simon CARLEY (Consultant in Emergency Medicine) (Presenter, Manchester)
15:10 - 15:40 Connecting education and patient care. Victoria BRAZIL (Presenter, Australia)

14:10-15:40
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B23
Italy invites
Anticoagulanti ed emergenze mediche

Italy invites
Anticoagulanti ed emergenze mediche

Moderators: Francesco BORGOGNONI (Italy), Giuseppe PEPE (Italy)
14:10 - 14:30 Stroke ischemico: vena, arteria o tutte due? Paolo CERRATO (Presenter, Italy)
14:30 - 14:50 Stroke emorragico: che succede con i NAO. Giancarlo AGNELLI (Presenter, Milano, Italy)
14:50 - 15:10 Embolia polmonare: trattarle tutte? Simone VANNI (Presenter, Florence, Italy)
15:10 - 15:30 Fibrillazione atriale: cosa è cambiato? Alberto CONTI (Presenter, Toscana, Italy)

14:10-15:40
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C23
Clinical Questions: Controversies
Infectious Disease & Sepsis

Clinical Questions: Controversies
Infectious Disease & Sepsis

Moderator: Christoph DODT (Head of the Department) (München, Germany)
14:10 - 14:40 Timing of antibiotics – Myth or fact? Eric BATARD (PU-PH) (Presenter, Nantes, France)
14:40 - 15:10 Controversies in the identification and treatment of sepsis. Colin GRAHAM (Director and Professor of Emergency Medicine) (Presenter, Hong Kong, Hong Kong)
15:10 - 15:40 Which goal to aim for in the ED during early-goal directed therapy in treatment of sepsis? Kurt ANSEEUW (Medical doctor) (Presenter, Antwerp, Belgium)

14:10-15:40
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D23
State of the Art
Obstetric Emergencies

State of the Art
Obstetric Emergencies

Moderators: Inger SONDERGAARD (PHYSICIAN) (ALLEROED, Denmark), Anna SPITERI (Consultant) (Malta, Malta)
14:10 - 14:40 The killers in obstetrics that you shouldn’t miss in your ED. Cornelia HÄRTEL (Medical Director of the ED, Consultant in EM, Director of Medical Education in EM) (Presenter, STOCKHOLM, Sweden)
14:40 - 15:10 Pelvic inflammatory disease. Maria Grazia FRIGO (Presenter, Italy)
15:10 - 15:40 Management of obstetric emergencies. Judith TINTINALLI (Professor) (Presenter, Chapel Hill NC, USA)

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E23
Research
Trauma

Research
Trauma

Moderators: Basar CANDER (Turkey), Pr Francesco DELLA CORTE (Head of Emergency Department) (Novara, Italy)
14:10 - 14:40 Decompressive craniectomy in traumatic brain injury. Hadie ADAMS (Presenter, United Kingdom)
14:40 - 15:10 Direct transportation to neurosurgical units for patients with isolated head injury. Fiona LECKY (Professor of Emergency Medicine) (Presenter, Sheffield, United Kingdom)
15:10 - 15:40 Predicting outcome in traumatic brain injury. Karim TAZAROURTE (Chef de service) (Presenter, Lyon, France)

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F23
YEDM
Sim Wars

YEDM
Sim Wars

Moderators: Pier Luigi INGRASSIA (Lugano, Swaziland), François LECOMTE (PH) (Paris, France)
Coordinators: Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Coordinator, Besançon, France), Youri YORDANOV (Médecin) (Coordinator, Paris, France)
Facultys: Elaine ERASMUS (Faculty, Cape Town, South Africa), Sian GERATY (Faculty, South Africa), Natalie MAY (Faculty, Oxford, United Kingdom), Patrick PLAISANCE (Head of Department) (Faculty, Paris, France), Thomas PLAPPERT (Medical Director EMS) (Faculty, Fulda, Germany), Dr Pieter Jan VAN ASBROECK (Consultant in Emergency Medicine) (Faculty, Genk, Belgium), Sabina ZADEL (Faculty, Slovenia)

14:10-15:40
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G23
Paediatric Track
Status of PEM in Italy

Paediatric Track
Status of PEM in Italy

Moderators: Ian MACONOCHIE (United Kingdom), Santiago MINTEGI (Section Head. Pediatric Emergency Department) (Bilbao, Spain)
14:10 - 14:40 Paediatric Emergency Medicine in Italy. Niccolò PARRI (Attending Physician) (Presenter, Florence, Italy)
14:40 - 15:10 Italian National Guidelines on Head Injury management in children in the ED. Liviana DADALT (Presenter, Italy), Silvia BRESSAN (Moderator) (Presenter, Padova, Italy)
15:10 - 15:40 Barriers and opportunities to the implementation of PEM. Simone RUGOLOTTO (Presenter, Italy)

14:10-15:40
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OP1-23
Oral Paper 1
Imaging and Ultrasound II

Oral Paper 1
Imaging and Ultrasound II

Moderators: Ammar ALANI (United Kingdom), Gregor PROSEN (EM Consultant) (MARIBOR, Slovenia)
14:10 - 15:40 #1180 - #1180 - Determining the clinical significance of errors in pediatric radiograph interpretation between emergency physicians and radiologists.
#1180 - Determining the clinical significance of errors in pediatric radiograph interpretation between emergency physicians and radiologists.

Study Objective

Emergency physicians (EPs) are expected to review and interpret plain radiographs in order to make treatment and disposition decisions. These radiographs are subsequently reported by a radiologist whose interpretation may differ. The clinical consequence of these discrepancies is uncertain. The objectives of this study were to a) review the rate and nature of radiograph discrepancies interpreted by emergency physicians versus radiologists in the pediatric emergency department, and b) determine the clinical significance of these discrepancies.

 

Methods

We conducted a retrospective review of discrepant radiology reports from a single site pediatric emergency department from October 2012 to December 2014.  All radiographs were initially interpreted by the staff emergency physician; where the final radiology impression differed, the report was identified as a ‘discrepancy’ per department protocol.  Radiographs were categorized as chest, abdomen, axial skeleton, upper extremity, lower extremity, soft tissue neck, or other.  Based on the final report, the discrepancy was classified as false positive, false negative or not a discrepancy.  Clinically significant errors that required a change in the management of the patient were tracked.

 

Results

There were 25,304 plain radiographs completed during the study period. Of these, 293 (1.16% of total radiographs) were identified by radiology as discrepant from the EP interpretation.  The most common were chest radiographs (41.6%) due to missed pneumonia, followed by upper and lower extremities (26.3% and 15.7% respectively) due to missed fractures.  Of 293 discrepancies, 208 (71.0%%) were false positives, 45 (15.4%) false negatives, and 40 (13.7%) were not true discrepancies upon further review.  One hundred and five (0.4% of all radiographs completed) were clinically significant, requiring subsequent change in patient management.

 

Conclusions

There is a low rate of discrepancy between emergency physician and radiologist interpretation of pediatric emergency radiographs.  The majority of errors are with radiographs of the chest and extremities. Educational efforts to improve emergency physician accuracy in interpretation of these types of radiographs may be beneficial. 


Jonathan TAVES (Hamilton, Canada), Steven SKITCH, Celine KIM, Rahim VALANI
14:10 - 15:40 #1882 - #1182 - The use of bedside ultrasound to assess fluid responsiveness in septic patients: increasing use in an Emergency Department High-Dependency Unit.
#1182 - The use of bedside ultrasound to assess fluid responsiveness in septic patients: increasing use in an Emergency Department High-Dependency Unit.

Introduction: The use of non-invasive strategies to assess fluid responsiveness of septic patients is spreading worldwide. Aim of this study was to assess the prevalence of bedside ultrasound evaluation of fluid responsiveness in a population of septic patients admitted in an Emergency Department High Dependency Unit (ED-HDU).

Methods: We identified two study periods: April, 2010-March, 2011 and February–December 2013 and we retrospectively analyzed all medical records of patients admitted in the ED-HDU in those periods with a diagnosis of sepsis/severe sepsis/septic shock. The evaluation of fluid responsiveness was performed considering the inferior vena cava collapsibility index, the left and right ventricular global systolic function and the presence of interstitial syndrome at the chest ultrasound.

Results: We retrospectively identified 126 septic patients in 2010 and 79 during 2013, mean age 73±14 years, 51% male gender, mean Sequential Organ Failure Assessment (SOFA) score 5.4±3.5.

The ultrasound evaluation of fluid responsiveness was carried out in a significantly greater proportion of patients in 2013 compared to 2010 (72/79, 91% vs 75/126, 60 %, p <0.0001). The proportion of patients in whom an ultrasound exam did not allow a definition of fluid responsiveness because of a bad acoustic window or lack of information in the medical record, remained comparable from 2010 to 2013 (29/75, 39% vs 27/72, 38%, p = NS).

The number of fluid challenges was similar between the patients evaluated and those not evaluated by ultrasound (82/126, 65% vs 33/56, 59%, p = NS).

Patients who were not assessed with ultrasound or in whom an evaluation was not possible were more frequently hemodinamically stable than patients assessed by ultrasonography (32/56, 57% vs 36/126, 29%, p=0.004).

Compared with patients treated empirically, patients evaluated by ultrasonography showed a SOFA score significantly higher both at the admission in ED-HDU (6.3 ± 3.6 vs 5.2 ± 3.4, p = 0.030) and after 24 hours ( 5.93 ± 3.6 vs 4.5 ± 3.0, p = 0.045), included a higher proportion of septic shock (32 vs 17%, p = 0.018) and a central venous catheter was placed more frequently (35 vs 19%, p = 0.015).

In the hemodynamically instable patients, stabilization was achieved more frequently in patients evaluated by ultrasound compared with patients treated empirically (32/126, 25% vs 11/114, 10%, p=0.0078).

The percentage of patients who never reached a hemodynamic stabilization was similar for patients with and without ultrasound evaluation (30/126 and 27/114 p = NS).

Conclusions: The bedside ultrasound evaluation of the fluid responsiveness in septic patients has significantly increased after a three year period. It was performed more frequently in hemodynamically instable patients than stable ones and it allowed to achieve a stabilization in a higher proportion of patients compared with empiric fluid administration. 


Margherita LUZZI (Firence, Italy), Lucia TAURINO, Irene TASSINARI, Beatrice DEL TAGLIA, Camilla TOZZI, Francesca INNOCENTI, Riccardo PINI
14:10 - 15:40 #1184 - #1184 - Impact of lung ultrasound findings in the assessment of acute heart failure in the emergency department.
#1184 - Impact of lung ultrasound findings in the assessment of acute heart failure in the emergency department.

Introduction:

 Lung ultrasonography (LUS) has recently emerged as a non-invasive tool for the differential diagnosis of pulmonary diseases. However, its use for the diagnosis of acute decompensated heart failure (ADHF) still raises some concerns. In patients with heart failure, many indexes are available for noninvasive identification of pulmonary congestion: plasma levels of brain natriuretic peptide (proBNP) (pg/ml); number of B-lines at lung ultrasound.

Objectives:

The primary goal of this study was to determine accuracy for diagnosing acutely decompensated heart failure (ADHF) with the use of B3 and B7 line patrons and the relation with proBNP.

 Methods:

 We conducted a prospective cohort study with 62 patients whom presenting with acute dyspnea, the emergency physician was asked to categorize the diagnosis as ADHF. Lung ultrasound was performed in all patients and B-lines were counted and compared before and after treatment. Finally, data were compared and quantitative and categorical variables were worked out along with other statistical analysis through estimated indicators.

Results:

The LUS was satisfied in 100 percent of patients. The LUS-implemented approach had a significantly higher accuracy, in the 63.9 % of studied patients we detected pulmonary edema with elevation of natriuretic peptides (sensitivity 88%; 95% CI, 85.3-91%; specificity 72.3%; 95% CI, 65-69%) and more number of B lines  (sensitivity 97.6%; 95% CI, 97-99.1%; specificity 93.5%; 95% CI 91.7-99.2%). The area under de ROC curve was of 0.91 (CI 95%: 0.83-0.93 p: 0.0001) with the higher point of sensibility in relation with B7 lines patron (sensitivity 96.2% and specificity 74.9%). In 45.5% of patients detected B3 lines patron after treatment with depletive diuretics.

Conclusions:

 The implementation of LUS with the clinical evaluation may improve accuracy of ADHF diagnosis in patients presenting to the emergency department. The B7 lines patron in LUS had been a good correlation with pulmonary edema.


Julio ARMAS CASTRO, Julio ARMAS CASTRO (Elche. Alicante, Spain), Blas GIMÉNEZ FERNÁNDEZ, Juan Carlos REAL LÓPEZ
14:10 - 15:40 #1317 - #1317 - Evaluation of the diagnostic accuracy of a lung ultrasound-implemented protocol for of acute dyspnea in the emergency department - a randomized controlled trial.
#1317 - Evaluation of the diagnostic accuracy of a lung ultrasound-implemented protocol for of acute dyspnea in the emergency department - a randomized controlled trial.

Background

Acute dyspnea is a diagnostic challenge for emergency physicians (EPs). The discrimination between cardiac and non-cardiac causes is essential for improving patients’ management. Lung ultrasound (LUS) has emerged as a non-invasive valuable tool for this diagnosis. We have recently shown in a multicenter study that the use of a LUS-implemented diagnostic  approach may improve the diagnostic accuracy in ED patients with acute dyspnea (Chest, 2015)..

 

Objectives

Aim of this study was to compare, in ED patients with acute dyspnea,  the diagnostic accuracy of a LUS-implemented approach with a standard diagnostic approach, that includes chest radiography (CXR) and natriuretic peptide measurement.

 

Patients and Methods

This was a randomized controlled multicentric trial involving two Italian EDs (AOU Città della Salute e della Scienza di Torino, and Careggi University Hospital, Florence). The study protocol was approved by the Ethical Commitees of the involved centers.

Patients presenting to the ED with acute shortness of breath as main complaint were eligible. After the initial clinical assessment (i.e. history, physical examination, ABG analysis and EKG), the EP was asked to discriminate the presuntive etiology of acute dyspnea (cardiac or non-cardiac). To complete the diagnostic evaluation, patients were subsequently randomized to either LUS (performed by the same EP – iLUS arm), or CXR and Nt-proBNP (iCXR arm).

A new presumptive diagnosis was recorded (iLUS or iCXR, respectively) using results of the diagnostic tests. At discharge from ED, a final ED dyspnea diagnosis, based on all diagnostic information available, was finally recorded. After hospital discharge, the entire medical records were independently reviewed by two expert EPs,  blinded to LUS results, in order to assign the etiology of patient’s dyspnea (in case of disagreement, a third operator, a certified cardiologist, reviewed the same clinical information  and assigned the final diagnosis). Sample size was calcolated as about 500 patients.


Results

Patients were enrolled from January, 2014 to March, 2015. Data are available for the first 205 cases (103 in iLUS arm; 41% of patients had cardiac  dyspnea; 12 cases needed to be assigned by cardiologist, 7 randomized to the iCXR arm). The median age was 79 years (range 28-100 years) (p-value >.05), M/F ratio was 0.95 (p-value >.05).

iLUS protocol had a sensitivity of 93.8% (95% CI 82.8-98.7) and a specificity of 94.5% (CI 84.9-98.9) for the diagnosis of cardiac dyspnea, with a ROC area of 0.94. iCXR diagnostic approach had a sensitivity of 86.1% (CI 70.5-95.3) and a specificity of 87.9% (CI 77.5-94-6), with a ROC area of 0.87.

Median evaluation time for implemented diagnoses was 3 minutes (range 2.5-15 minutes) for iLUS, and 92 minutes (range 64-265 minutes) for iCXR.

 

Conclusions

Preliminary results (based on less than half of the patients enrolled in this RCT) suggest that the iLUS protocol has a higher diagnostic accuracy for the diagnosis of cardiac dyspnea in patients admitted to ED than the iCXR approach, nowadays considered the standard of care.


Emanuele PIVETTA (Torino, Italy), Pietro TIZZANI, Federica BOVARO, Maria TIZZANI, Camilla TOZZETTI, Monica MASOERO, Luca PIGOZZI, Maria Grazia VEGLIO, Francesca GIACHINO, Paolo BARON, Fulvio MORELLO, Valeria BUSSO, Paolo FASCIO PECETTO, Davide CASTAGNO, Giulio PORRINO, Milena M MAULE, Andrea EVANGELISTA, Paolo QUAGLIA, Ottavio DAVINI, Stefano GRIFONI, Corrado MOIRAGHI, Peiman NAZERIAN, Alberto GOFFI, Enrico LUPIA
14:10 - 15:40 #1402 - #1402 - Specificity of Bedside Ultrasound to diagnose Renal stones/hydronephrosis in the Emergency Department.
#1402 - Specificity of Bedside Ultrasound to diagnose Renal stones/hydronephrosis in the Emergency Department.

Specificity of Bedside Ultrasound to diagnose Renal stones/hydronephrosis in the Emergency Department

 

Introduction :

Flank pain is considered one of the very common presentations of patients in Emergency Departments on a daily basis. Due to the high sensitivity and specificity of CT scan, it has become the standard imaging modality for evaluating acute flank pain with the potential of renal claculi. The introduction of emergency department US however has made it one of the most preferred initial modalities for detecting renal stones considering the fact that it is commonly available, inexpensive and risk free when it comes to radiation exposure. 

Several studies have looked into the sensitivity and specificity of US compared to CT in diagnosing renal stone disease. Moreover, the advantages of US being radiation free, more time and cost effective might make it a better option in the management of an ED patient. 

 

2. Objectives :

To compare bedside US with CT in detecting renal calculi and hydronephrosis in adult patients presenting to ED with  acute flank pain. 

 

3. Study design :

Prospective diagnostic cohort study of adult patients presenting to ED with acute flank pain. Patients had a bedside US by an emergency physician in ED prior to CT (gold standard) to assess for signs suggestive of renal calculi/ hydronephrosis. The findings of the bedside imaging were documented in the patients' chart with an indication of whether or not any signs of renal calculus or hydronephrosis are detected. CT scans were reported by the radiologist who does not get an access routinely to the chart during the patient's active ED visit. 

 

4. Inclusion criteria :

All adult patients (18 years and older) who present with acute flank pain and not previously diagnosed to have renal calculi.

 

5. Exclusion criteria:

Patients who have been already diagnosed with renal stones. 

 

6. Setting:

The study was carried out in the Emergency department of University hospital Birmingham.

 

 

8. Consent :

A verbal consent was taken from all the patients and documented in the notes.

Results:

The results were very reassuring. We had total 24 patients in our pilot study.  8 were females and 16 were male. The mean age was 54years (28-90). All the patients had departmental US followed by the CT KUB. The bedside ultrasound showed sensitivity of 83.3% (95% CI= 36-97%), specificity 100% (95% CI= 82-100%), negative predictive value 95% (95% CI= 75-99%) and positive predictive value 100% (95% CI= 48-100%).

 

Conclusion:

Our results clearly show the effectiveness of bedside ultrasound in the hands of ED physicians. Patients without evidence of stones and hydronephrosis on ED bedside US could be safely assumed to have no stones or less than 6 mm if detected on CT. The smaller stones typically do not require surgical intervention. Hence based of the clinical judgement patients with negative US can be discharged home or further imaging can be requested.

 

 


M Azam MAJEED, Noora ALSUKAITY (Birmingham, United Kingdom), Ahmed AL HUBASHI

14:10-15:40
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OP2-23
Oral Paper 2
Neurological Emergencies

Oral Paper 2
Neurological Emergencies

Moderator: Gautam BODIWALA (Leicester, United Kingdom)
14:10 - 15:40 #1088 - #1088 - Can patients at high risk of non-convulsive seizure be identified in the emergency department?
#1088 - Can patients at high risk of non-convulsive seizure be identified in the emergency department?

Background: Non-convulsive seizure and non-convulsive status epilepticus (NCS/NCSE) might present with altered mental status (AMS) without any sign or symptom of seizure. Our previous work has revealed that 5% of ED patients with AMS have NCS/NCSE. Since EEG is not routinely available in the ED, most cases of NCS are not diagnosed in the ED. More than 50% of NCS cases are diagnosed more than 24 hours after ED presentation, and usually in the intensive care unit. Objective: To identify the clinical findings that could predict high risk of NCS/NCSE in ED patients with AMS.

Methods: Retrospective analysis of prospectively collected data. Inclusion criteria: Adult ED patients with AMS. Exclusion: Patients with immediately correctable cause of AMS (e.g. hypoglycemia, narcotic overdose). EEGs were recorded upon presentation and were interpreted by on-call epileptologists within one hour of recording. EEGs were recorded either by standard EEG and microEEG (Bio-Signal Group Inc.) or by microEEG alone. Proportions are presented as percentages with 95% CI. Continuous variables are presented as medians and quartiles (25%,75%). Group comparisons are performed with Mann-Whitney U or Fisher’s exact tests, when appropriate (alpha 0.05, two-tailed).

Results: We enrolled 332 patients with AMS (median age: 66 [quartiles: 50,78), 50% male). In total, 16 patients were diagnosed with NCS (5%, 95%CI, 3 - 8%). Only age was significantly different between the NCS vs. Non-NCS groups (p = 0.032). Previous history of seizure was reported only in 63% (95%CI, 39 - 82%) of NCS patients. Only 31% (95%CI, 14 - 56%) of NCS patients had abnormal neurological exam (other than AMS). Among patients who had head CT, only 20% (95%CI, 6 - 46%) had abnormal findings. Because of the small number of NCS cases, performing a multivariate analysis was not possible.

Conclusion: Increase in age is associated with higher risk of NCS/NCSE in AMS patients. There are no other clinically useful variables that could predict or increase the pre-test probability of NCS/NCSE in such patients. ED physicians ought to have a high index of suspicion for NCS/NCSE in ED patients with AMS. EEG should be the standard of care in all patients with undifferentiated altered mental status.


Shahriar ZEHTABCHI (Brooklyn, USA), Samah ABDEL BAKI, Ahmet OMURTAG, Andre FENTON, Richard SINERT
14:10 - 15:40 #1187 - #1187 - sumatriptan and propofol VS Sumatriptan and placebo in acute migraine.
#1187 - sumatriptan and propofol VS Sumatriptan and placebo in acute migraine.

Introduction: Headache are responsible for 2.2% of emergency department visits .Triptans are used as a migraine specific medication to terminate migraine headach attacks . Although triptans have been introduced as asafe and effective treatment for migraine attacks this class of drugs has well known side effects and contraindications.Several studies have shown that subanesthetic doses of propofol areefficacious as rescue therapy for acute migraine headache in adult andchildren.In this study we are comparing the effect of infusion propofol with subcutaneus sumatriptan in treatment of acute migraine headache.

Method: This study is the randomized double blind prospective clinical trial.Ever 35 known migraine paitent meeting the international headache society (IHS) criteria are enrolled in this study and randomly allocated into two groups.In first group 30 microgaram per kilogaram propofol infused in 100cc normal salin in 1 hour with 6 mg sumatriptan subcutaneus injected.In the second group 6 mg sumatriptan subcutaneous injected with placebo.

Result:There are significant differences between the two groups in respons to treatment.The primary outcome (pain intensity) is significant lower 30 minutesafter treatment in group one (pvalue< 0.05). In group one 75% of the paitent had vertigo and sleepy that improved10 minutes  after completion of drug.In second group 66.7% of the paitent had chest tightness. No paitent had hemodynamic instability in both group.

Conclusion: This study has shown that sumatriptan and propofolis  more effective with faster respons and better pain control 30minutes after treatment than sumatriptan and placebo.


Reza FARAHMAND RAD, Akram ZOLFAGHARI SADRABAD (TEHRAN, Islamic Republic of Iran), Marziyeh GHILIAN, Mohammad Davood SHARIFI
14:10 - 15:40 #1357 - #1357 - Relationship between full outline of unresponsiveness score coma scale and glasgow coma scale of stroke patients in emergency room, Siriraj hospital.
#1357 - Relationship between full outline of unresponsiveness score coma scale and glasgow coma scale of stroke patients in emergency room, Siriraj hospital.

Relationship between full outline of unresponsiveness score coma scale and glasgow coma scale of stroke patients in emergency room, siriraj hospital

Surabenjawong U, M.D.*, Sonmeethong W, M.D.*, Prayoonwiwat N, M.D.**, Nakornchai T, M.D.*,

*Department of Emergency Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700.

Background: The Full Outline of Unresponsiveness Score Coma Scale (FOUR score), a recent coma score, was developed to solve some limitations of the well-known Glasgow Coma Scale (GCS). From previous studies, FOUR score can predict the neurological outcome in an intensive care and traumatic patients better than GCS. However, there is no report in stroke patients.

Methods: The prospective cohort study was conducted in adult patients, diagnosed with acute stroke in emergency department of Siriraj hospital. Patients with history of previous head injury were excluded. Every patient was evaluated with both FOUR score and GCS by trained emergency physicians. The primary outcome was the correlation between both scores. The Modified Rankin Scale (MRS), Cerebral Performance Category (CPC) and 3-month mortality rate predicted by FOUR score and GCS were defined as the secondary outcomes.

Results: After analyzing data of 60 stroke patients in emergency department, mean FOUR score of the population was 14.05 (SD 4.02) and mean GCS was 12.45 (SD 3.74). FOUR score and GCS had an excellent correlation with r = 0.821 (p value <0.001). With cut-off point for mortality prediction of 10 and 9 for FOUR score and GCS respectively, FOUR score predicted 3-month mortality rate better than GCS with area under the curve (AUC) of 1.00 (p value <0.001, 95% CI 0.94-1.00) while AUC for GCS was 0.99 (p value <0.001, 95% CI 0.92-0.99). FOUR score was also outstanding in predicting the poor neurological outcome (MRS 4-6 and CPC 3-5) with cut-off point of 10 (AUC of 1.00, p value <0.001, 95% CI 1.00-1.00). Meanwhile, the GCS with cut-off point of 9 had AUC for predicting neurological outcome of 0.94 (p value <0.001, 95% CI 0.91-1.02).

Conclusion: FOUR score and GCS had an excellent correlation for evaluating the consciousness in acute stroke patients. FOUR score is not inferior to GCS for predicting 3-month mortality and poor neurological outcome.

Keywords: acute stroke, Full outline of unresponsiveness score coma scale, Glasgow Coma Scale


Usapan SURABENJAWONG (Bangkok, Thailand), Thanyaporn NAKORNCHAI, Weeraphon SONMEETHONG
14:10 - 15:40 #1496 - #1496 - Delays to diagnostic brain imaging in childhood arterial ischemic stroke.
#1496 - Delays to diagnostic brain imaging in childhood arterial ischemic stroke.

Background: Acute ischemic stroke (AIS) in children is an uncommon but potentially devastating condition. Prompt recognition is crucial to guide appropriate management in the acute care setting. The gold standard for the diagnosis of stroke is brain magnetic resonance imaging (MRI). Long delays to diagnosis are the most important barrier to thrombolysis in children. This may be a consequence of both delayed presentation to medical attention and in-hospital factors including limited access to diagnostic brain imaging.

Objective: primary outcome was to determine the time to first neuroimaging in children diagnosed with ischemic stroke. Our secondary aim was to identify patient and process factors that contributed to delayed neuroimaging.

Design/Methods: Retrospective study of children with a radiologically confirmed stroke in a tertiary care center, RCH Melbourne, between January 2003 and December 2012. Data on presentations to a referring hospital prior to transfer to our center were also collected.

Results: 71 episodes of AIS and 19 of TIA were recorded. The time from symptom onset to hospital arrival was 2.5h (IQR 1-19) for patients who first presented to another hospital and 3.6h (IQR 1.3-18.5) for first presentations to our center. Overall time from hospital arrival to first neuroimaging was 3.3h (IQR 1.2-8.3). 66% of children received CT as the first imaging modality in a median time of 1.5h (IQR 1.0-3.7), but the scan was only diagnostic in 25% of cases, whilst MRI was the first imaging performed in 34% of cases, in a median time of 3.9h (IQR 1.4-13.7) and it was diagnostic in 100% of AIS. Time to final diagnosis (on either CT or MRI) was 11.3h (IQR 4.1-22.5). Sedation was used in 28% of children (12% of CT scans and 41% of MRI scans). Children who underwent their first scan more than 3h after hospital presentation were more likely to receive an MRI as first neuroimaging modality (OR 10.75, 95% CI 3.56-33.72) and to have a final diagnosis of TIA (OR 7.34, 95% CI 2-33). Use of sedation was not significantly associated with a delay in neuroimaging (OR 1.83, 95% CI 0.67-4.97).

Conclusions: Despite the poor diagnostic accuracy, CT was still the first neuroimaging modality performed in the majority of patients with AIS, often within 3 hours from arrival. MRI had superior sensitivity to CT, but was more likely to be performed beyond this time window. Use of sedation did not seem to be associated with delayed neuroimaging. Development of acute stroke imaging protocol to maximise diagnostic yield in minimum time are urgently needed.


Marco DAVERIO (Padova, Italy), Mark MACKAY, Silvia BRESSAN, Franz BABL
14:10 - 15:40 #1497 - #1497 - Recurrent childhood arterial ischemic stroke management in the emergency department.
#1497 - Recurrent childhood arterial ischemic stroke management in the emergency department.

Background: Acute ischemic stroke (AIS) is uncommon in childhood, but recurrent strokes occur relatively frequently (up to 1/3 of the patients), particularly in cases with atherosclerotic arteriopathies and cardiac disease. The gold standard for the diagnosis is magnetic resonance imaging (MRI). Whilst significant delays in the diagnosis have been previously reported in children with a first episode of AIS, recurrences should be recognized earlier and time to final diagnosis reduced.

Objective: To describe the clinical characteristics, time to diagnostic neuroimaging and differences in the acute management of recurrent AIS episodes compared with first presentations.

Design/Methods: Retrospective study in a Pediatric tertiary referral hospial of children diagnosed with AIS between January 2003 and March 2014. Data on presentations to referring hospitals prior to transfer were also collected.

Results: 70 patients were included with a mean follow up of 5.6 years (SD 2.3). Of these, 11 subjects had a total of 23 episodes of recurrent stroke, occurring at a median of 208 days (IQR 37-395) after the index stroke. Patients with a recurrence were older (median age 8.04 vs 6.23 years) and more often females (82.6% vs 55.7%, p=0.021). Recurrent episodes tended to arrive more often by private car and presented with signs and symptoms different to first presentations (less non-focal/diffuse features, like altered mental status and vomit, less focal motor features, like focal limb weakness and dysarthria and more nuanced symptoms, like focal numbness). All the 70 patients with a first AIS underwent neuroimaging, whereas neuroimaging was not performed in 3 recurrent episodes, where a clinical diagnosis of TIA was made after neurology consultation. Computed Tomography (CT) was the first scan modality in 2/3 if first strokes but still the first in 50% of the recurrences, being diagnostic in 17% of cases overall. Time from symptom onset to hospital arrival was not significantly shorter for patients with a recurrence (p>0.05). Time to first and diagnostic scan was significantly longer for patients with a recurrent episode compared with first presentations (respectively p=0.015 and p=0.021).

Conclusions: Knowledge of prior stroke does not seem to have a positive effect on decreasing time delays to arrival at hospital or time to brain imaging. Most recurrent strokes were associated with self-limited symptoms. Despite the low diagnostic accuracy CT scan was still the first neuroimaging performed in half of the recurrent episodes. Development of acute stroke imaging protocol to maximise diagnostic yield in minimum time are urgently needed in children.


Marco DAVERIO (Padova, Italy), Silvia BRESSAN, Franz BABL, Mark MACKAY
14:10 - 15:40 #1596 - #1596 - When life runs out in seconds - high-speed thrombectomy protocol in ischemic stroke.
#1596 - When life runs out in seconds - high-speed thrombectomy protocol in ischemic stroke.

Background: In ischemic stroke caused by a thrombosis of a large brain artery, two million neurons, 12 kilometers of axons and 14 billion synapses are lost every minute. IV-thrombolysis (IV-tPA) in such cases appears ineffective, while mechanical thrombectomy (MT) is reported to be a powerful tool to open the occlusion (1). However, the favorable effect of recanalization is highly time-dependent (2). American Stroke Association recommends a door-to-punction time shorter than 120 minutes. At Tampere University Hospital approximately 70 patients per year are presently treated with MT. Since 2013, we have used a validated MT protocol that includes key personnel from paramedics to interventional neuroradiologist. Hence, we wanted to evaluate the current efficacy of our protocol. Previously, consecutive series of patients with door-to-recanalization time of less than 90 minutes on average have not been reported.

Materials and Methods:  From 1.1.-12.4.2015, all consecutive MT patients were identified from our hospital records. We collected the following data: symptom onset time, door-to-punction time, door-to-recanalization time, NIHSS (National Institutes of Health Stroke Scale) at arrival and at 24h post recanalization, and TICI (Thrombolysis In Cerebral Infarction) score 0-3 (0=no flow- 3=complete tissue reperfusion).  A total of 18 consecutive patients (mean NIHSS 17 at arrival, range 6-22) treated with MT were identified, of whom 14 were also treated with IV-tPA.

Results: Our preliminary results show that the median door-to-punction time was 25 minutes (range 14 min – 1h 33min) and the median door-to-recanalization time was 66 minutes (range 30 min – 128min). The median symptom-onset-to-recanalization time was 4 h 40 minutes (excluding 3 wake-up-strokes). Recanalization was not achieved in two patients. The remaining 16 had a minimum TICI score 2b and displayed a favorable outcome at 24 hours (mean NIHSS 6, range 0-19).

Discussion:  Early reperfusion is the main factor predicting good outcome in stroke recanalization therapy. Our current protocol enables systematic high-speed recanalization in patients with proximal brain artery thrombosis. We achieved at least TICI 2b recanalization in 90% of the cases.

 

References:

  1. Berkhemer OA, Fransen PS, Beumer D et al. A randomized trial of intraarterial treatment for acute ischemic stroke. N Engl J Med. 2015 Jan 1;372(1):11-20.
  2. Mazighi M, Meseguer E, Labreuche J et al:  Dramatic recovery in acute ischemic stroke is associated with arterial recanalization grade and speed. Stroke. 2012 Nov;43(11):2998-3002.

Tessa TILLGREN (Tampere, Finland), Satu-Liisa PAUNIAHO, Pasi JOLMA, Jutta KERÄNEN, Juha-Pekka PIENIMÄKI, Henna SIIPPAINEN, Hannu PÄIVÄ, Jyrki OLLIKAINEN
14:10 - 15:40 #1707 - #1707 - The Relationship Between Optic Nerve Sheath Diameter Measured on Computerized Tomography and Mortality in Patients with Cerebrovascular Infarction.
#1707 - The Relationship Between Optic Nerve Sheath Diameter Measured on Computerized Tomography and Mortality in Patients with Cerebrovascular Infarction.

OBJECTIVE: We aimed to assess the possible correlation between optic nerve sheath diameter (ONSD) measurements on initial brain computerized tomography (CT) images and National Institutes of Health Stroke Scale (NIHSS), Glasgow Coma Scale (GCS) and the relationship with mortality in ischemic stroke patients admitted to Emergency Department.
FINDINGS: Total of 143 patients were included to this study. Case group was constituted from 70 patients and the control group from 73. Mean age of the case group (n=70) was 72.1±12.9(32-95), and 51.2% of the patients were female and 48.8% were male. Control group mean age (n=73) was 68.9±10(35-88), 53.7% of the patients were female and 46.3% of the patients were male.There was no statistically significant difference among groups in terms of gender distribution and mean age (p=0.437).The case and control groups were observed having similar comorbidities, however, statistically significant differences were only detected in terms of HT, previous cerebrovascular event and DM risk factors between the case and control groups. Mean ONSD values measured on CT were 5.52±0.76 mm for the right eye and 5.79±0.85 mm for the left eye in the case group and 5.04±0.52 mm for the right eye and 4.95±0.58 mm for the left eye in control group. According to these results, a significant difference was determined between right and left eye mean ONSD measurement values in the case and control group patients (for right ONSD, p=0.01; for left ONSD, p=0.01). Mean hospitalization time of the case group patients were 16.1 days and mean duration of stay in intensive care unit was 13.7 days. Mean NIHSS points of the case group was 9 and mean GCS score was 14. There was no significant difference between survivors and non-survivors in the case group in terms of each eye ONSD values (for right ONSD, p=0.84; for left ONSD, p=0.73).
RESULTS: There is a linear relationship between intracranial pressure and optic nerve sheath diameter meaurement values on unenhanced brain computerized tomography images in ischemic stroke patient population. Final data of our study indicate that ONSD measurement values could be used for prediction of intracranial pressure in ischemic stroke patient population but for the prediction of mortality, ONSD measurement values alone stand insufficient. Optic nerve measurement on brain tomography images can be used as an non-invasive method for detection of increased intracranial pressure in cases where invasive intracranial monitorization is contraindicated or alternative non-invasive monitorization devices such as USG are not availible.


Mehmet Akif ONAL, Sedat KOCAK (KONYA, Turkey), Gulay SAHINER ONAL, Necdet POYRAZ, Muhammet Rasit OZER, Mustafa GULPEMBE, Basar CANDER
14:10 - 15:40 #1932 - #1932 - Causes of emergency vertigo stratified by age and gender.
#1932 - Causes of emergency vertigo stratified by age and gender.

Introduction:

Vertigo is a common complaint of patients who seek care in the emergency department (ED). In terms of signs and symptoms, overlap exists among the many potential causes. The report of symptoms can be vague, inconsistent, or unreliable. Life-threatening disorders can masquerade as benign disorders. What are the main causes of emergency vertigo?

 

Objective:

 

To explore the causes of emergency vertigo stratified by age and gender to improve the diagnostic efficiency

 

Methods:

 

A prospective observational study was conducted over seven months. All the patients presented to the ED with vertigo were included. The demographics, co-morbidities, clinical and biological data and in-hospital procedures were collected. The etiologies were identified and stratified by age and sex.

 

Results:

Inclusion of 122 patients. Mean age 53  +/- 16 years. Sex ratio = 0.87.  Comorbidities n (%): hypertension 39 (32%), Diabetes 23 (19%), history of vertigo 52 (43%), coronary artery disease 7 (6%), stroke 9 (8%). Mortality was 1%. The top three diagnoses were benign paroxysmal positional vertigo (BPPV in 91 cases, 75%), central vertigo in 13 patients (PCI, 11%) and hypertensive peak in 9 cases (7,4%).

 

Stratified by age, the main cause of vertigo for the patients < 30 years (N=12) is BPPV (100%). For the patients aged between 30-45 years (N= 30), BPPV was found in 25 patients (83%), central vertigo (n = 2, 7%), iatrogenic cause, hypertensive peak and CO poisoning in one patient each. BPPV (n=26, 75%), psychological factors (n=3, 8%), central vertigo (n=2, 6%), iatrogenic cause (n=2,6%), one patient had cardiac cause and another patient  CO poisoning, for 45-60 years group (N=35). For the group of patients aged between 60-75 years old (N=35), central vertigo was found in 8 cases (23%), BPPV was found in 20 cases (57%), hypertensive peak (n=7, 20%), cardiac cause (n=2, 6%) and psychological factors in one case. For the elderly group > 75 years (N=10), BPPV was found in 8 (80%) of patients, and central vertigo in 1 (10%), hypertension was found in one patient (10%).

 

Stratified by gender, there was no difference for the main three etiologies: BPPV, central vertigo or hypertensive peak. But psychological factors were more common in women, and cardiac causes more found in men.

 

Conclusion:

 The main causes of emergency vertigo were: BPPV, central vertigo and hypertensive peak. BPPV should be considered initially when vertigo was triggered repeatedly by positional change, especially for young patients. In elders with vertigo, central vertigo and hypertension were common. In women psychological factors should be considered and diagnosis and treatment should be offered timely.

 


Rania JEBRI (Lyon), Anware YAHMADI, Soumaya MAHDHAOUI, Sami SOUISSI, Mouna GAMMOUDI, Wided BOUSSLIMI, Sawsen CHIBOUB, Mahbouba CHKIR
14:10 - 15:40 #893 - #893 - Ischemic Preconditioning Maintains Immunoreactivities of Glucokinase and Glucokinase Regulatory Protein in Neurons of the Gerbil Hippocampal CA1 Region Following Transient Cerebral Ischemia.
#893 - Ischemic Preconditioning Maintains Immunoreactivities of Glucokinase and Glucokinase Regulatory Protein in Neurons of the Gerbil Hippocampal CA1 Region Following Transient Cerebral Ischemia.

Glucokinase (GK) plays a key role in the control of blood glucose homeostasis. In the present study, we investigated the effect of ischemic preconditioning (IPC) on immunoreactivities of GK and its regulatory protein (GKRP) following 5 min of transient cerebral ischemia in gerbils. The gerbils were randomly assigned to 4 groups (sham-operated-group, ischemia-operated-group, IPC plus (+) sham-operated-group and IPC+ischemia-operated-group). IPC was induced by subjecting the gerbils to 2 min of ischemia followed by 1 day of recovery. In the ischemia-operated-group, a significant loss of neurons was observed in the stratum pyramidale (SP) of the hippocampal CA1 region (CA1) at 5 days post-ischemia; however, in the IPC+ischemia-operated-group, neurons in the SP were well protected. In the immunohistochemical study, immunoreactivities of GK and GKRP in neurons of the SP were distinctively decreased in the CA1, not CA2/3, from 2 days post-ischemia, and hardly detected in the SP at 5 days post-ischemia. In the IPC+ischemia-operated-group, immunoreactivities of GK and GKRP in the SP of the CA1 were similar to those in the sham-group. In brief, our findings show that IPC dramatically maintains immunoreactivities of GK and GKRP in neurons of the SP of the CA1 after ischemia-reperfusion and indicate that GK and GKRP may be necessary for neurons to survive against transient cerebral ischemia.


Jun Hwi CHO, Chan Woo PARK, Taek Geun OHK, Yoon Sung KIM (Chuncheonsi, Republic of Korea), Myoung Chul SHIN, Moo Ho WON
14:10 - 15:40 #901 - #901 - The impact of thrombolytic treatment or endovascular thrombectomy on oxidant-antioxidant status and lymphocyte DNA damage in patients with acute ischemic stroke.
#901 - The impact of thrombolytic treatment or endovascular thrombectomy on oxidant-antioxidant status and lymphocyte DNA damage in patients with acute ischemic stroke.

Purpose: This study aimed to investigate the impacts of thrombolysis and thrombectomy on lymphocyte DNA damage and oxidative stress parameters for the treatment of adult patients with ischemic stroke in early post-stroke period (within the first 4-6 hour of stroke) based on clinical and radiological findings.

Materials and methods: Over a 7-month period (May 2014 through November 2014), 62 consecutive adult patients who presented to the Emergency Department of Bezmialem Vakif University and diagnosed as an acute ischemic stroke were included in this prospective clinical study. Thirty-two patients who met the inclusion criteria and 30 eligible healthy volunteers as control subjects were enrolled. Patients were divided into 3 groups according to their National Institute of Health Stroke Scales (NIHSS) on admission. Additionally, patients were stratified into three different groups based on modified Rankin Scale (mRS) at 24 h after thrombolytic treatment or endovascular thrombectomy. Plasma lymphocyte DNA damage and Total Oxidant Status (TOS), Total Antioxidant Status (TAS) and Oxidative Stress Index (OSI) were assessed in all groups classified with respect to NIHSS and mRS, both on admission and at 24 h after the treatment. The results were compared between the groups.

Results: Plasma TOS and OSI levels and lymphocyte DNA damage were found to be significantly higher, whereas plasma TAS levels were significantly lower in patients with stroke compared with those in the controls (all comparisons, p<0.001). According to the comparison of NIHSS groups with respect to the stroke severity; increased lymphocyte DNA damage levels and decreased TAS levels were observed (p< 0.001 and p=0.034, respectively). When the patients were classified into subgroups with respect to mRS, plasma TOS and OSI levels and lymphocyte DNA damage tended to be higher in group 3 which comprised patients with the most neuronal dysfunction compared to those in groups 1 and 2 (p=0.003, p=0.001 and p=0.006, respectively).

Conclusion: Lymphocyte DNA damage and TAS, as biomarkers of early oxidative changes can be regarded as an objective alternative criterion to the stroke assessment scales for determining severity of brain damage in patients with ischemic stroke. Additionally, lymphocyte DNA damage, TOS and OSI levels as an early biological indicators can help to identify neurologic health and well being and to evaluate the effectiveness of thrombolytic treatment or endovascular thrombectomy in such patients.


Eda YIGIT, Ozgur SOGUT (Istanbul, Turkey), Mehmet YIGIT, Ali DUR, Kenan TURKDOGAN, Taha Okkes KÜCUKDAGLI

16:10
16:10-17:40
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A24
State of the Art
Disaster & Biohazards

State of the Art
Disaster & Biohazards

Moderators: Massimo AZZARETTO (Medico Specialista) (Lugano, Switzerland), Pr Ives HUBLOUE (Chair) (Brussels, Belgium)
16:10 - 16:40 Mass civilian shootings: Are we ready to face this new threat? Alain PUIDUPIN (Médecin anesthésiste réanimateur) (Presenter, Paris, France)
16:40 - 17:10 Quarantine and isolation: Understanding public health measures to manage an outbreak. Kristi KOENIG (Presenter, USA)
17:10 - 17:40 Training in disaster medicine: technology available for new challenges. Pier Luigi INGRASSIA (Presenter, Lugano, Swaziland)

16:10-17:40
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B24
Italy invites
Il Micro e il Macro nel paziente critico

Italy invites
Il Micro e il Macro nel paziente critico

Moderators: Mauro CHIESA (Italy), Andrea MAGNACAVALLO (Italy)
16:10 - 16:30 Non si vede ma c'è. Fernando SCHIRALDI (Presenter, Napoli, Italy)
16:30 - 16:50 Meglio sapere che c'è. Rodolfo SBROJAVACCA (Presenter, Udine, Italy)
16:50 - 17:10 Se c'è si deve vedere. Roberto COPETTI (Presenter, Latisana, Italy)
17:10 - 17:30 Mettiamo insieme i pezzi del puzzle. Gian CIBINEL (Presenter, Torino, Italy)

16:10-17:40
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C24
Clinical Questions: Controversies
Trauma

Clinical Questions: Controversies
Trauma

Moderators: Simon CARLEY (Consultant in Emergency Medicine) (Manchester), Fiona LECKY (Professor of Emergency Medicine) (Sheffield, United Kingdom)
16:10 - 16:40 How should we teach trauma care in 2015? Mary Rose CASSAR (Presenter, Zebbug, Malta)
16:40 - 17:10 Trauma systems: Local care or major trauma centre? Raed ARAFAT (Presenter, Romania)
17:10 - 17:40 Is it all about the golden hour? Francesca INNOCENTI (PHYSICIAN) (Presenter, Florence, Italy)

16:10-17:40
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D24
EuSEM meets
ACCA / ESC

EuSEM meets
ACCA / ESC

Moderators: Pr Abdelouahab BELLOU (Director of Institute) (Guangzhou, China), Madalenna LETTINO (ACCA President Elect) (Italy)
16:10 - 16:40 Acute Cardiac Care Association of the European Society of Cardiology: Past, present, future and collaboration with EuSEM. Madalenna LETTINO (ACCA President Elect) (Presenter, Italy)
16:40 - 17:10 Pragmatic Use of cardiac biomarkers in the emergency department. Mario PLEBANI (Presenter, Italy)
17:10 - 17:40 Pragmatic Management of Atrial Fibrillation in the Emergency Department. Pr Abdelouahab BELLOU (Director of Institute) (Presenter, Guangzhou, China)

16:10-17:40
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E24
Research
Infectious Disease & Sepsis

Research
Infectious Disease & Sepsis

Moderators: Christoph DODT (Head of the Department) (München, Germany), Jean-Louis VINCENT (consultant) (Bruxelles, Belgium)
16:10 - 16:40 Early sepsis detection. Christian HOHENSTEIN (PHYSICIAN) (Presenter, BAD BERKA, Germany)
16:40 - 17:10 Blood sugar in septic ED patients? Important or useless to consider? Christoph DODT (Head of the Department) (Presenter, München, Germany)
17:10 - 17:40 Reducing late sepsis complications in the Emergency Department. Jean-Louis VINCENT (consultant) (Presenter, Bruxelles, Belgium)

16:10-17:40
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F24
YEDM
Sim Wars

YEDM
Sim Wars

Moderators: Pier Luigi INGRASSIA (Lugano, Swaziland), François LECOMTE (PH) (Paris, France)
Coordinators: Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Coordinator, Besançon, France), Youri YORDANOV (Médecin) (Coordinator, Paris, France)
Facultys: Elaine ERASMUS (Faculty, Cape Town, South Africa), Sian GERATY (Faculty, South Africa), Natalie MAY (Faculty, Oxford, United Kingdom), Patrick PLAISANCE (Head of Department) (Faculty, Paris, France), Thomas PLAPPERT (Medical Director EMS) (Faculty, Fulda, Germany), Dr Pieter Jan VAN ASBROECK (Consultant in Emergency Medicine) (Faculty, Genk, Belgium), Sabina ZADEL (Faculty, Slovenia)

16:10-17:40
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G24
Paediatric Track
Scenario-based Guidelines in PEM

Paediatric Track
Scenario-based Guidelines in PEM

Moderators: Dr Thomas BEATTIE (Senior lecturer) (Edinburgh, United Kingdom), Ian MACONOCHIE (United Kingdom)
16:10 - 16:35 Simulation of Head Injuries. Silvia BRESSAN (Moderator) (Presenter, Padova, Italy)
16:35 - 17:00 Simulation of Anaphylaxis. Dr Cathelijne LYPHOUT (Consultant in EM) (Presenter, Ghent, Belgium)
17:00 - 17:25 Simulation of Breathlessness. Youri YORDANOV (Médecin) (Presenter, Paris, France)
17:25 - 17:40 Speakers' Forum. Ian MACONOCHIE (Presenter, United Kingdom)

16:10-17:40
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OP1-24
Oral Paper 1
Administration & Healthcare Policy

Oral Paper 1
Administration & Healthcare Policy

Moderators: Gautam BODIWALA (Leicester, United Kingdom), Pr Lisa KURLAND (speaker) (Örebro, Sweden)
16:10 - 17:40 #967 - #967 - ER throughput: staff perceptions of delays.
#967 - ER throughput: staff perceptions of delays.

Background: There are many potential delays in throughput in a busy academic emergency department. Identifying these delays can help the organization serve patients better and more efficiently. Perceptions vary regarding which factors contribute most to delays in throughput.

Objectives: This study aims to identify some of these factors and analyze the perceptions of delays among staff members.

Methodology: All full-time clinical staff of the University of Chicago emergency department were asked to select the top 5 delays (among 19 options) that detract from overall throughput. Staff was also asked to choose the top 5 improvable delays in throughput. Responses were sorted by group: attending, resident, nurse and technician. The percent of total participants within one group that selected a particular option was compared to the other groups.

Results: Response rate among physicians was 56% while response rates among other staff was 34%. 50% of all responses were physicians while 50% were other staff members. The top selections among physicians were: waiting for consultants, image acquisition, inpatient bed assignments, distractions and lab results. The top selections among ancillary staff were: physician decision time, inpatient bed assignments, waiting for consultants, radiologist read of images, image acquisition.

Discussion: All groups indicated that the largest perceived delays are outside of the ER’s control. Staff within one group typically characterized the largest delays as ones that fall within the responsibility of another group, minimizing delays their own group is accountable for. The largest perceived delays tend to be operations that a group is least involved with or disrupts a group’s own workflow.

Conclusion: Better communication between staff groups is needed to understand delays contributing to overall workflow.  Since perceptions of delays are so varied among staff groups, data-driven methodologies to improve workflow are important to avoid fallacies related to perceptions in overall ER throughput delays. 


Spiegel TOM, Archit GULATI (Chicago, USA)
16:10 - 17:40 #1473 - #1473 - Factors associated with lenght of stay in a Spanish Emergency Department.
#1473 - Factors associated with lenght of stay in a Spanish Emergency Department.

Introduction: Length of stay (LOS) is a key measure of emergency department (ED) throughput and a marker of overcrowding. Excess LOS in the ED has been identified as a relevant indicator for measuring quality of care in the ED and has been linked to an increase in risk for patients. Time studies that assess key ED processes could help clarify the causes of patient care delays and prolonged LOS and contribute to develop innovative and cooperative strategies that should lead to improving patient flow within the ED and improve quality of care and patient satisfaction.

Objective: This abstract aims to identify factors associates with LOS in the ED in a University Hospital in Madrid, Spain.

Methods: This study was conducted at the General ED of Hospital La Paz, a University urban tertiary care centre located in Madrid, Spain. Hospital La Paz catchment area covers 850.000 people. The ED saw over 104.000 patients a year and is staffed by 24 attending emergency physicians. Hospital La Paz ED consists of three levels of care: I. Walk-in clinic (WIC); II. Emergency Care Unit (ECU); III. Acute Medical Care Ward (AMCW), with 24 beds. The source of information for this work was a statistical representative sample obtained from all patients attending the General ED of Hospital La Paz from 3 years: 2008 (33,7%), 2010 (28,1%) and 2013 (38,2%). The sample selected patients from 3 months (August, February, May, November), and 3 days of the week (Sunday, Monday, Wednesday). Information was retrospectively extracted from medical records as well as from clinical administrative data bases. Analysis was conducted through multivariable linear regression considering LOS in the ED as dependent variable.

Results: Overall, data was obtained from 956 patients, being 54.2% female, and 3.3% functionally dependent. 59.3% were allocated to the WIC, 7.1% to the ECU, and 33.4% to the AMCW. Mean age was 55.7 and Charlson index was 1.5. Mean LOS was 552.5 minutes and median was 315.0 minutes. A hospital admission was indicated for 19.8% of all patients. The most relevant use of clinical resources was: consultation with specialists (32.5%), urinalysis (10.0%), diagnostic imaging (46.9%), and blood test (60.5%).

No significant differences in LOS were obtained by number of patients attending the ED, year, month, day of the week, hour of admission to the ED, age, sex or Charlson index. Variables showing a significant effect on LOS in a multivariable regression analysis were: dependency status, level of care, blood tests, diagnostic imaging, urinalysis, consultation with a specialist, and type of discharge from the ED. An interaction was found between hospital admission and level of care, as patients admitted to the AMCW who were eventually hospitalized have lower LOS than patients who were discharged from the ED.

Conclusions: These data shows that both internal (requesting of both consulting and diagnostic services, and the process of care in the AMCW) and external factors (delivery of consulting services and diagnostic tests) should be investigated in a comprehensive research-based strategy aimed at optimizing LOS in the ED.


Antonio SARRÍA SANTAMERA (Madrid, Spain), Ana MARTÍNEZ VIRTO, Manuel QUINTANA DIAZ
16:10 - 17:40 #1848 - #1848 - Fever in the under five's: Impact of an integrated electronic health record on compliance with national standards on documentation and management.
#1848 - Fever in the under five's: Impact of an integrated electronic health record on compliance with national standards on documentation and management.

Background: The National Institute of Health and Care Excellence (NICE) in the UK mandates standards for the assessment, documentation and management of children under 5 years presenting with fever (Clinical Guideline 130). Auditing compliance with these standards has always been hampered by poor documentation. Fully integrated health care records offer an opportunity to not only improve documentation but also to implement clinical decision tools and links to patient information resources.

Methods: We compared documentation and management of 50 consecutive febrile (temperature > 37.5 degrees C) paediatric patients aged under 5 years presenting to our emergency department before (2012) and four months (December 2014) after the introduction of a fully integrated electronic health record system (EPIC). This type of electronic health care record is widely used in the US (69% of children's hospitals) but our Hospital is one of the first in the UK to adopt such a system. Five standards were assessed:

1) Use of the NICE traffic light system (clinical decision tool) when assessing febrile children in the ED

2) Recording of observations (temperature, heart rate, respiratory rate, capillary refill time and blood pressure)

3) Safety netting information provided to families

4) Appropriate use of antibiotic treatment

5) Investigations performed in children of the highest risk category

Results:

Standard 1: The children's risk category could be determined from the documentation in 84% of cases (90% in 2012), no reference to the use of the NICE tool was made by any of the clinicians. The tool is available for reference in the ED but not integrated as a decision tool in EPIC. This was no different to the previous audit in 2012.

Standard 2: Althought the recording of baseline observations was similar, the documentation of capillary refill time and blood pressure had dropped (see table 1).

Observation

Standard achieved in 2015

Standard achieved in 2012

Temperature

98%

100%

Heart rate

98%

95%

Respiratory rate

98%

95%

CRT/BP

38%

64%

Standard 3: The proportion of patients in the intermediate category that had appropriate safety netting advice given and documented in the record was 66% in 2014 compared to 36% in 2012, although the numbers were small.

Standard 4: Antibiotic prescribing was appropriate in 100% of cases (no different to 2012).

Standard 5: Documentation of appropriate investigations performed in the highest clinical risk group had dropped from 100% in 2012 to 80% since introduction of EPIC.

Conclusion: EPIC does not appear to have resolved the problem of poor documentation. Severity was not determinable in a greater percentage of cases compared with 2012. Documentation of safety netting is still lacking, albeit improved since 2012. Improvements have been seen in the measurement and recording of the observations temperature, heart rate and respiratory rate. However, recording and documentation of capillary refill time and blood pressure still remains much lower than in 2012. The prescription of antibiotics appears to be in accordance with NICE guidelines. Implementation and integration of clinical decision tools may be required at system design stage to improve compliance with national standards.


T.f.a. MARSHALL-ANDON (Cambridge, United Kingdom), Peter HEINZ
16:10 - 17:40 #1026 - #1026 - Patients’ knowledge about drugs prescribed and the transmission of medical information in the healthcare circuit : A prospective study.
#1026 - Patients’ knowledge about drugs prescribed and the transmission of medical information in the healthcare circuit : A prospective study.

Background: Quality medical care means that physicians have the appropriate medical information. The objective of this study is to evaluate the medical information in thehealthcare circuit (i.e knowledge about prescription medications and quality of referral letters).

Methods: We present here a prospective multicentric study of 892 patients, from December 2013 to July 2014 within 3 Emergency Departments (ED) including 648 patients. In outpatient care, 133 patients were interviewed by 3 specialists and 111 patients in 2 general practices.

Results: In our study, 30.6% of patients getting to the ED are more than 75 years old (versus 15.4% in outpatient care). 65.5% of primary care patients have optimal treatment knowledge versus 43.4% in the ED (12.3% for ≥ 75 years old). A statistically significant relationship was established between age or polypharmacy and knowledge of treatment. 11.3% of patients have full knowledge of their treatment (when more than 5 items were prescribed). Patients referred by general practitioners (GP) in the ED were 3.6 times more likely to not know their treatment. We also studied the relationship between high risk medication (such as: vitamin K antagonist, antiplatelet, psychotropic drugs, antibiotics) and treatment knowledge. Patients consuming these drugs have 7 times less likely to have an optimal knowledge and were 3.6 times more addressed to the ED. Only 18% of patients consulting at the ED have structured referral letters (anamnesis, clinical examination, argued hypothesis). The quality of GP's letters was unsatisfactory, only 36.2% were well structured. Those of the Emergency medical service were of even lower quality: 9.0% were structured. When the patient is admitted in the ED, he is most likely to ignore its treatment: more than 50% of patients are unable to quote it. Using an individualized treatment card could be a reliable way to transfer medical information.

Conclusion: Our study based on the transmission of medical information reveals that the population most at risk of treatment ignorance is the one older than 75 years, with a treatment consisting of more than 5 items and with prescription medication having a high risk of iatrogenic complications. The proportion of elderly patients is increasing in all ED. The assessment phase on arrival is fundamental and determines the future orientation of the patient. Our key objective in the ED is to identify fragile patients. Quality medical care begins with appropriate communication between physicians.


Céline RENFER (Strasbourg), Carmen HAMMANN, Hakim SLIMANI, Fanny SCHWEITZER, Charles-Eric LAVOIGNET, Mihaela MIHALCEA-DANCIU, Pierrick LE BORGNE, Pascal BILBAULT
16:10 - 17:40 #1614 - #1614 - How emergency medicine senior doctors spend their time at the emergency department; systematic review of time and motion studies.
#1614 - How emergency medicine senior doctors spend their time at the emergency department; systematic review of time and motion studies.

Review question How senior emergency doctors spend their time at the emergency department (ED).

Background Given the demands placed on senior doctors in terms of time and expertise, it is valuable to summarise the literature that describes and quantifies how senior emergency doctors utilize their time. A better understanding of this will, in turn, assist policy makers to maximise the potential benefits that senior doctors confer. The secondary objective for the review was to create a standardized classification of activities that are performed in the ED by senior doctors in order to assist researchers in this field who may use this list of activities for collaborative research.

Design Systematic review.        

Data sources Databases searched included: Cochrane Library, MEDLINE, EMBASE, CINAHL, and Web of Science. Reference lists and citations of the retrieved studies were scrutinized for additional studies.

Review methods Databases were searched for Time motion studies (TMS) examining the role how senior doctor spend their time in the ED published from 1998 to 2014. Studies were included if they were observational TMS or work-sampling studies , undertaken in Type I adult or mixed population EDs and described the activities of senior doctors.  The systematic literature search was followed by assessment of risk of bias of each individual study fulfilling the inclusion criteria using an evidence-based quality appraisal developed by the authors. Data extraction was based on a form designed and piloted by the authors.

Data synthesis Narrative synthesis was performed.

Results Ten TMS were included in the review. The majority were small single-site studies conducted in academic EDs in developed countries. Generally, studies were liable to several biases including observer and Hawthorn bias. Time spent on direct patient care was the most commonly reported outcome. Direct patient care occupied around 28.1 to 40% of the senior doctors’ time with a mean, median of 33 and 32.7 respectively. In comparison, indirect patient care was reported by five studies where it referred to all activities apart from direct care. This ranged from 51.3% - 69% for academic senior emergency doctors and 45% for community ED senior emergency doctors. Time spent on communication was reported in seven studies. It ranged from 8.3%-42%. Eight studies reported data on documentation. It ranged from 8.5% in the most recent study by Kee et al., to 28% as reported by Chisholm. Teaching and supervision was included in the categorisation of all studies except three but no particular trend was detected. Personal time or social time was reported in six studies. This accounted for 3% to around 17% of the senior doctors’ time.

Conclusion: Senior doctors spend a significant amount of time on activities related to indirect patient care. Senior emergency doctors can manage several tasks concurrently in an interrupt-driven and busy environment. It is also proposed to use the suggested category classification presented in this review (table format) in future studies looking at time analysis of doctors in an ED setting.



 


Maysam ABDULWAHID (Sheffield, United Kingdom), Janette TURNER, Suzanne MASON
16:10 - 17:40 #1615 - #1615 - The impact of senior doctor assessment at triage on emergency department performance measures: Systematic review and meta-analysis of comparative studies.
#1615 - The impact of senior doctor assessment at triage on emergency department performance measures: Systematic review and meta-analysis of comparative studies.

ABSTRACT

Study question To determine if placing senior doctor at triage versus standard single nurse in a hospital emergency department (ED) improves ED performance by reviewing evidence from comparative design studies using several quality indicators.

Design Systematic review.        

Data sources Cochrane Library, MEDLINE, EMBASE, CINAHL, Cochrane Effective Practice and Organisation of Care (EPOC), Web of Science, Clinical trials registry website. In addition, screening studies references, citation search were used to identify relevant studies.

Review methods Databases were searched for comparative studies examining the role of senior doctor triage, published from 1994 to 2014. Senior doctor was defined as a qualified medical doctor who completed high specialty training in emergency medicine. Articles with a primary aim to investigate the effect of senior doctor triage on ED quality indicators such as waiting time (WT), length of stay (LOS), left without being seen (LWBS) and left without treatment complete (LWTC) were included. Articles examining the adverse events and cost associated with senior doctor triage were also included. Only studies with a control group, either in a randomized controlled trial (RCT) or in an observational study with historical controls, were included. The systematic literature search was followed by assessment of relevance and risk of bias of each individual study fulfilling the inclusion criteria using Effective Public Health Practice Project EPHPP bias tool. Data extraction was based on a form designed and piloted by the authors for dichotomous and continuous data.

Data synthesis Narrative synthesis and meta-analysis of homogenous data was performed.

Results Of 4506 articles identified, 25 relevant studies were retrieved; 12 were of the weak pre-post study design, 9 were of moderate quality and 4 were of strong quality. The majority of the studies revealed improvements in ED performance measures favoring senior doctor triage. Pooled results from 2 homogeneous Canadian RCTs showed a significant reduction in LOS of medium acuity patients (WMD -26.26 min 95%CI -38.50 to -14.01). Another 2 RCTs revealed a significant reduction in WT (WMD -26 min, 95%CI -31.68 to -20.65). LWBS was reduced in 2 Canadian RCTs [RR = 0.79, 95% CI 0.66 to 0.94]. This was echoed by the majority of pre-post study designs. Senior doctor triage did not change the occurrence of adverse events. No clear benefit of senior doctor triage in terms of patient satisfaction or cost effectiveness could be identified.

Conclusion This review demonstrates that senior doctor triage (SDT) can be an effective measure to enhance ED performance, although cost versus benefit analysis is needed. The high risk of bias in the nature of evidence identified, however, mandates more robust multi-centered studies to confirm these findings.


Maysam ABDULWAHID (Sheffield, United Kingdom), Andrew BOOTH, Maxine KUCZAWSKI, Suzanne MASON

16:10-17:40
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OP2-24
Oral Paper 2
Education and Simulation Training / Point of Care Research

Oral Paper 2
Education and Simulation Training / Point of Care Research

Moderators: Lars Petter BJORNSEN (Emergency Physician) (Trondheim, Norway), Gregor PROSEN (EM Consultant) (MARIBOR, Slovenia)
16:10 - 17:40 #1183 - #1183 - The RESPECT EM! (NL) Project: Research Education and Stimulation Program Creating Tomorrow’s Emergency Medicine in the Netherlands.
#1183 - The RESPECT EM! (NL) Project: Research Education and Stimulation Program Creating Tomorrow’s Emergency Medicine in the Netherlands.

The RESPECT EM! (NL) Project

Research Education and Stimulation Program Creating Tomorrow’s Emergency Medicine in the Netherlands

A collaborative effort by the Departments of Emergency Medicine of UCSF/Fresno and Westfriesgasthuis

 

Introduction

Published scholarly activity by Dutch emergency physicians has markedly trailed the overall development of the specialty of EM in the Netherlands.  In a 2013 Dutch study by Koning et al (1), EM trainees revealed that “scientific research should be facilitated more.”  The same study concluded that, “Even though research and publications are essential to positioning EM as a fully qualified specialty, residents lag behind in a research role.  While they were stimulated to undertake research, they received very little support.”  The same is true for EM trainers, supervisors and faculty members.  Another 2013 study by Ahmed et al found that structured residency research programs are associated with higher resident research productivity and publication rates (2).

 

Objectives

With this perspective in mind, Westfriesgasthuis EM Residency Directors approached a US-based consultant with research and medical writing expertise.  The thought being that a consultant could quickly and easily “import” research and medical writing capability into an ED primed to receive that knowledge.  A team of resident and faculty physicians was assembled at the Westfriesgasthuis to participate in the project, the endpoint of which is publication of at least one scholarly project by each team member.

 

Methods

The program’s timeline is 36 months.  It starts with an intensive series of facilitated face-to-face educational sessions.  Early topics to be covered include: research and medical writing – why do it?; problems and blocks to research initiation, progress and completion; research resources; performing a medical literature search; article/publication types; funding one’s project; publication/presentation venues; collaborating with others; framing a publishable project; and statistics.  All participants will have at least one defined publishable project ready to start at the end of this intensive seminar series.  Thereafter, the research consultant will be available electronically to mentor and advise program participants.  Three months after the start, the research consultant will return for face-to-face sessions to further participant’s progress.  Interim progress assessments and project assistance will be provided by the Residency Directors.  As participant’s projects near completion, editing and article submission will be assisted by return on-site visits. 

 

Conclusion

We see RESPECT EM! as a valuable model for others in EM wishing to spur the development of their own research and medical writing programs.

A descriptive article detailing the RESPECT EM! project will be readied for submission to a scientific journal.

 

References

(1) Koning SWGaakeer MIVeugelers R. Three-year emergency medicine training program in The Netherlands: first evaluation from the residents' perspective. Int J Emerg Med. 2013;6(1):30.

(2) Ahmad SDe Oliveira GS JrMcCarthy RJ. Status of anesthesiology resident research education in the United States: structured education programs increase resident research productivity. Anesth Analg. 2013;116(1):205-10.


Michael D BURG, Matthijs R DOUMA (Hoorn, The Netherlands), Eva P BAERENDS, Tom BOEIJE, Nieke MULLAART-JANSEN
16:10 - 17:40 #1348 - #1348 - Point of Care Emergency department Acute Rapid Laboratory (PEARL): win win for the lab and for ED?
#1348 - Point of Care Emergency department Acute Rapid Laboratory (PEARL): win win for the lab and for ED?

Background: We evaluate the impact on the throughput process for patients’ with the implementation of a dedicated laboratory POCT Acute Rapid Laboratory protocol (PEARL) in the Emergency Department.

Methods :Comparative study of Turnaround time (TAT) delays for Troponin, Brain Natriuretic Peptide (BNP), D Dimers before and after the implementation of a POCT in ED (41,000 visits/year) during 2 months (Feb-March 2014-2015). We used the Lean process to analyze time to send blood samples from the ED to the Central laboratory : Turnaround Time (TAT), delay for results, impact on Length of Stay (LOS). Patients’ characteristics: sex ratio, age, medical chief complaints, level Triage (Australian Triage Scale), TAT for urgent (routine process) and very urgent for critical ill patients, delay for results and LOS. 

Results: during the same period (01/02 to 31/03) the number of ED visits was similar (+5%) 6748 patients (2014) vs 7354 (2015). We analyzed 1354 vs 1812 blood samples for Tn, BNP and D Dimers. We use lab tests for rapid diagnosis for patients’ chief complaints like chest pain , coma dyspnea with/without an acute respiratory distress, Congestive Heart Failure (CHF)or for patients in the resuscitate room with life threatening conditions (4% of total ED visits).Turnaround Time with POCT was significant (p<0,05) shorter with an average earlier (- 55 to 74,8 mn) for results for Troponin, D Dimers and BNP with the PEARL Protocol (Fig.1) . The average Length of Stay (LOS) was significant shorter (- 55 mn) for patients with Triage Scale Level 1 of severity.

Discussion: Patient’s flow in the ED and the Lean process focus on the throughput model have a significant impact on the timeliness and quality of care in the ED. In literature, Point of Care Testing (POCT) has been found to increase the number of patients discharged in a timely manner, expedite triage of urgent but non-emergency patients, and decrease delays to treatment initiation. Using POCT, caregivers can perform, analyze, obtain, and act on test results at the bedside significantly faster than if samples were sent out to a central laboratory. If used effectively, POCT has the potential to decrease delays to treatment initiation, increase ED efficiency, optimize transport for blood samples to the Central lab, influence patient care positively and alleviate the negative effects of long waiting times. Close collaboration with the central laboratory Department is necessary to evaluate PEARL protocol’s impact for quality care and on financial cost for patients.

Conclusions: Prolonged waiting times and treatment delays can have substantial effects on patient outcomes . Rapid TATs from POCT represent clinical decision making and a good quality care patient management . When used in the appropriate context, our POCT PEARL protocol reduce delays to treatment initiation in the critically ill, improve outcomes, increase timely patient rates for frequent complaints like chest pain, rapid diagnosis of Myocardial Infarction, Thrombosis or Congestive Heart Failure. Costs of POCT per analysis seem to be outweighed by the total gain of expedited patient flow in the appropriate setting.


Eric REVUE (Paris), Laurence BURC, Martine VEILLARD, Antoine LAUDAT, Dominique PELIE, Alexandre HENNIART, Stephanie LEGROS
16:10 - 17:40 #1380 - #1380 - POCT in the Emergency Department: Impact of POCT-Technology on Efficiency and Effectiveness of the Treatment Process in Emergency Departments.
#1380 - POCT in the Emergency Department: Impact of POCT-Technology on Efficiency and Effectiveness of the Treatment Process in Emergency Departments.

Background

In many German hospitals, emergency departments (ED) suffer from crowding effects caused by an extended average length of stay (ALOS single troponin test: 2h 54 min; ALOS serial troponin tests: 7h 12 min). Due to the fact that between 30 % and 70 % of patients entering the ED do not require emergency-status, the waiting times for troponin (cTn) test results of patients with “non-specific thoracic pain” (12 % of ED-patients) are one reason for non-acceptable LOS in the ED. In addition, the variation in the turn-around-time (TAT) between collecting the blood sample and availability of test results fluctuates between 42 and 121 minutes (average TAT = 73 minutes): a non-controlled process with high variance and a blockade of ED resources.

Objectives

The objective of this study was to clarify to what extent a POCT-solution for troponin contributes to avoiding crowding effects and to reducing LOS of ED-patients. Additionally, the impact of how an investment into POCT pays off in terms of reducing staff workload and containing costs was examined. Furthermore, the importance of learning curve effects and the employees' resistance to change were analyzed.

Methods

A randomized single-center trial was conducted at a university-affiliated hospital with 80.000 ED patient visits per year. In the first study phase, cTn measurement of patients with suspicion of NSTE-ACS was performed in a central laboratory setting (62 patients). One week after having implemented a POCT-solution for cTn, another 46 patients were observed in terms of therapeutic turn-around-time (tTAT) and LOS in the ED (second phase). Six months later, the third phase including 48 patients took place. Again, tTAT and LOS were measured and learning curve effects were analyzed. To compare the central laboratory and the POCT-setting, ED-staff who performed POCT (26 people) were queried on different items (e.g. satisfaction with workflow effectiveness; patient risks ) in order to identify resistance to change and the acceptance of the POCT-setting in all three phases of the study.

Results

POCT was associated with an accelerated availability of cTn test results (lab: 72 min; POCT: 15 min), a shorter time to physician notification of cTn level (90 min; 48 min) and a reduced ALOS by 54 minutes. Furthermore, a potential of cost savings between 560 and 1.100 € p.d. was identified.

Conclusion

POCT for cTn measurement has clinical relevance for ED patients with “non-specific thoracic pain,” especially for high-risk patients with a low suspicion of ACS (“late responders”). POCT contributes to reducing “crowding effects,” containing process costs, and increasing patient satisfaction because of reduced ED waiting times. A POCT-setting for cTn measurement is significantly more acceptable to the ED staff than in a central lab setting.

Discussion

A change of setting from central lab testing to POCT in fact means a shift of workload from lab to ED-staff. The employees’ motivation to use a new implemented technology as a part of a new workflow organization is crucial to achieve a high level of effectiveness and efficiency. This level could be leveraged if additional parameters critical to therapy are measured by POCT (e.g. CRP).


Wilfried VON EIFF (Muenster, Germany), Markus WEHLER, Daniel JANSEN
16:10 - 17:40 #1386 - #1386 - Agreement between emergency physician and cardiologist in left ventricular function evaluation after short training.
#1386 - Agreement between emergency physician and cardiologist in left ventricular function evaluation after short training.

Background: Delayed diagnosis and treatment in shock patients may lead to multiorgan dysfunction syndrome (MODS) and eventually death. Volume status assessment in shock patient is a crucial key to guide early management in emergency room. Nowadays, limited echocardiography becomes an important tool to assess volume status because it is non-invasive and easily to perform.

Methods: Cross sectional study was conducted in emergency department, Siriraj hospital from October to December 2014. The patients presented with shock or uncertain volume status were included. All investigators underwent short course training in limited echocardiography, including lecture and workshop. Emergency physicians (EP) performed echocardiography and classified left ventricular function (LVF) into 3 categories; good, moderate and poor contraction. A blind cardiologist re-evaluated all video files and estimated LVF to determine a correlation using kappa statistic.

Results: Ninety-seven patients compatible with inclusion criteria were enrolled. Of these, overall agreement between EP and cardiologist was 79.4% and weighted kappa was 0.73. Percentage of LVF correlation estimation between EP and cardiologist in good, moderate and poor contraction were 62%, 9.8% and 7.6%, respectively. Accuracy in diagnosis pericardial effusion was 100%. The most appropriate view rated by cardiologist was subxyphoid view (94.6%) and the least appropriate view was apical 5-chamber view (70.7%).

Conclusions:  Emergency physician with short training in limited echocardiography can assess LVF by visual estimation with high agreement compare with cardiologist.  


Apichaya MONSOMBOON (Bangkok, Thailand), Thiti PATARATEERANON, Surat TONGYOO
16:10 - 17:40 #1676 - #1676 - The death in simulation randomized trial: effect of simulated patient death on emergency worker’s anxiety.
#1676 - The death in simulation randomized trial: effect of simulated patient death on emergency worker’s anxiety.

Study objectives: The outcomes on learners of simulated patient death remain controversial. A few studies reported conflicting results, and psychological and cognitive effects on learners are unclear. We sought to assess the impact of simulation-based training with unexpected manikin death on the learners ‘anxiety when facing life threatening situation (LTS).

Methods: We conducted a prospective multicenter randomized trial on teams that work in an emergency department (ED). Each team included a core of one resident, two nurses and one care giver. They participated in a simulation-based training with a scenario of a 35 year old man in the ED with ventricular fibrillation due to a Brugada syndrome. We randomly assigned each team in two groups: after three shocks, the patient returns in spontaneous cardiac activity (life group LG), or the patient ends in asystole (death group DG). To ascertain the death, the learners were told that patient was declared dead after 45 min of advanced life support. Subjects were aware that they participated in a study about emotional responses in the settings of LTS and they were told during the pre-course that manikin’s death was an eventuality. Our primary endpoint was the assessment of anxiety when facing a LTS, evaluated through the State part of the State-Trait Anxiety Inventory (STAI). Participants were asked to fill this questionnaire before, then one month after the course. We recorded data on their satisfaction on a 1-10 scale. We used the paired Student t-test for comparison of parametric data. Gaussian distributed variables are expressed as mean (Standard deviation SD) and non-Gaussian as median [25-75 interquartile range IQR]. We calculated the exact 95% confidence interval (CI) for mean differences.

Results: Forty subjects were included in the pilot study. Five were excluded as they refused to complete the study. Amongst the 35 analyzed participants, they were 22 in the DG and 13 in the LG, including eight (22%) residents, 14 (43%) nurses, nine (25%) care givers and four (10%) medical students. Mean age was 28 years (SD 6) and 71% were women. Median duration of the scenario and debriefing was 14.6 min [IQR 14.4-14.7] and 25.0 min [IQR 22.6-27.1] respectively. Before the simulation training, median baseline STAI score was 45 [IQR 38-51], similar in both groups (45 [IQR 40-52] in LG vs 44 [IQR 36-50] in DG, p=0.36). Median STAI score was significantly improved at one month after the session, with a mean difference of 5.1 (95%CI [2.5 – 7.7]). We report a trend towards greater reduction in the DG, although not significant: 6.1 (95% CI [1.9 – 10.0]) vs 3.5 (95% CI [0.6 – 6.3]) in LG, p=0.30. Satisfaction of the learners was excellent in both groups, with a median rate of 10 [IQR 8 – 10].

Conclusions: Simulation based training on LTS reduced anxiety amongst learners, whether the manikin died or not. We report a trend towards higher stress reduction at one month after a simulated patient death.


Anne-Laure PHILIPPON (Paris), Jérôme BOKOBZA, Amélie HURBAULT, Bruno RIOU, Alexandre DUGUET, Yonathan FREUND
16:10 - 17:40 #1871 - #1871 - Point of Care Ultrasound; Are we practicing safely?
#1871 - Point of Care Ultrasound; Are we practicing safely?

Point of Care Ultrasound; Are we practicing safely?

 

Introduction

Clinicians increasingly use Point of Care Ultrasound (PoCUS) as an adjunct to history and examination to facilitate crucial clinical decision-making. This is frequently seen in Emergency Medicine in the United Kingdom to a degree that acquisition of Level 1 competency in PoCUS is now compulsory for Emergency Medicine higher specialty trainees. However little is known about the scale of use of PoCUS by clinicians, especially in relation to its governance (reporting, recording, storage, supervision/review and audit). Therefore we conducted a survey looking into clinical governance of Point of Care Ultrasound in the Yorkshire and Humber region in the United Kingdom.

Methodology

We conducted a survey within the Yorkshire and Humber region looking in to the governance of Point of Care Ultrasound in Emergency Departments. The questionnaire comprised of questions related to usage and governance.

Results

Out of the 18 Emergency Departments we inquired, 13 replied (72.22%), of which 3 are trauma centres and 6 are trauma units. All departments have US machines with M mode, B mode and colour doppler capabilities and have curvilinear and linear transducers. Every department uses PoCUS for FAST, AAA, ECHO in life support and Central & Peripheral vascular access. Around 50% of the departments utilise PoCUS for foreign body removal, shock assessment and DVT diagnosis while 30-40% use it for regional anaesthesia and hepato-biliary studies.

7 out of the 13 (54%) departments have a dedicated PoCUS lead . While Emergency Medicine Consultants and middle grades/ registrars use the US machine in every department, other specialty clinicians use the same machine in 2 (15%) departments.

Only 4/13 (30%) of departments store the images in Picture Archiving and Communication System (PACS) and the rest of the departments store them in either on the US machine hard drive or as thermal prints. 10/13 (77%) departments record the report directly on patient notes while 4/13 (31%) record them in templates.

 9/13 (70%) of the departments do not have built in “safety net” where 4/13 (30%) of the departments have a safety net where non-signed off operators’ scans are supervised immediately or reviewed on a later date by a Level 1 or 2 accredited operator. Only 3/10 (23% ) of the departments have an audit process in place and only  5/13 (38%) has a written policy/ guideline on governance of use of Point of Care US in ED.

Conclusion

From our survey it is clear that Point of Care Ultrasound is used widely by Emergency physicians in their departments. It also highlights deficiencies and inconsistencies around governance in recording, reporting, safety netting and auditing. We feel this needs to be urgently addressed in order to comply with nationally agreed Radiology Guidelines to ensure the safe use of PoCUS by clinicians. Our Emergency Department has developed a Clinical Governance Policy for Point of Care Ultrasound and are in the process of developing a Trust Point of Care Ultrasound Policy to include all clinicians undertaking Point of Care Ultrasound in their clinical practice.  


Asoka WEERASINGHE, Zafir AHMED (Dewsbury, United Kingdom), Chamika MAPATUNA, Alison MCGUINESS
16:10 - 17:40 #1879 - #1879 - Bridging the Gap: Interprofessional Mental Health Simulation-Based Training in the Emergency Department to Improve Collaborative Working.
#1879 - Bridging the Gap: Interprofessional Mental Health Simulation-Based Training in the Emergency Department to Improve Collaborative Working.

Background

It has been recognised that increasing numbers of patients are presenting to Emergency Departments (ED) in mental health crisis, whilst access to specialist psychiatric services in certain areas is limited.  In addition, there is a high need for early recognition of mental health problems and a call for more continuous provision of care.  Collaborative working between emergency department staff and mental health clinicians is essential in providing high quality care for patients presenting with mental distress.  We describe and evaluate an interprofessional mental health simulation-based training (SBT) course for front line staff working in an inner city ED. 

 

Aims

The primary aim was to improve collaborative working across specialties and professions when caring for patients with mental health difficulties in the ED.

 

Methods

A half-day interprofessional SBT course was developed in which participants engaged in three scenarios following one simulated patient’s journey through the ED.  A debrief model was used to allow participants to learn positively and constructively from their shared experiences. 

Changes in participants’ attitudes were examined using pre and post self-rating questionnaires.  Statistical analysis was conducted using Wilcoxen Rank Signed Rank Test.  Qualitative data was obtained from follow-up focus groups, which further examined participants’ experience of being in the simulation, and their integration of learning into practice. 

 

Results

37 individuals of a broad professional mix participated:  security officers, ED nurses, emergency medicine residents, psychiatry residents, and mental health nurses. 

Attitude scores moved in a positive direction significantly for half the items.   Most significant was increased comfort with the participants’ own roles and responsibilities as a member of the multidisciplinary team (p = 0.004) and with those of other team members (p = 0.011) when caring for patients with mental health difficulties.

Thematic analysis of follow-up focus groups revealed that the intervention encouraged reflection on other professions’ perspectives and consideration of colleagues’ particular skills and expectations when working with patients who present in mental health crisis.  Participants reflected on how they would put into practice “joint working” by sharing information and involving other team members from different disciplines earlier.

 

Conclusions

This study presents evidence that interprofessional SBT is an effective tool in encouraging teams to reflect on factors which impact on effective collaborative working when managing patients presenting in mental health crisis in the ED.  Further work is needed to establish whether this leads to a sustained cultural change across the ED.


Humphreys ROSEMARY (, ), Simon CALVERT, Sean CROSS
16:10 - 17:40 #1947 - #1947 - A retrospective analysis of ambulance arrivals at a major trauma unit in South Wales: are emergency services being used appropriately.
#1947 - A retrospective analysis of ambulance arrivals at a major trauma unit in South Wales: are emergency services being used appropriately.

Introduction: Inappropriate use of emergency medical services has been discussed for over a decade within mainstream media and medical publications. The majority of epidemiological studies and investigations into this problem have been from the ambulance service, reporting service abusers and 999 calls that do not result in transportation to hospital. This study analyses the patient cohort who have dialled 999 resulting in transportation to hospital, with medical assessment, diagnosis and outcome of the attendance contributing towards the decision of whether the call to emergency service was appropriate or inappropriate.

 

Method: We conducted a retrospective analysis of all ambulance admissions at a Major Trauma Unit in South Wales. The emergency department notes of all patients arriving by ambulance from January 1st though March 31st 2015 were reviewed. Key information regarding presenting complaint, triage disposal, clinical observations, diagnosis, treatments required and outcome of attendance were collated. These contributred toward an overall analysis of appropriate utilisation of the emergency medical services in the local area.

 

Results: 6600 ambulances attended A&E during the 3 month study period, including 11 air-ambulance retrievals, representing 35.4% of total patient attendances. From this cohort, 2426 patient (36.8%) were either admitted or transferred to another specialist centre. 4174 patients (63.2%) did not require admission, 37.6% were referred back to the general practitioner, 12.5% were discharged with no follow-up necessary, 4.1% were discharged with a follow-up in the emergency department, 4.2% referred to other outpatient health services, and 314 patients (4.8%) discharged themselves against medical advice, or failed to wait for assessment.

 

Conclusions:

Following medical assessment within the emergency unit, over 60% of patients required minimal or no intervention, and monitoring in the community by the patient or GP services was the most frequent outcome. Additional sources of ambulance utilisation included: over-reactions from minor injuries or ailments, concern from surrounding persons, and immediate perceived difficulties in transport were among reasons for dialling 999. Ease of access in panicked situations resulted in a default cry for help. For some patients, key phrase triggers when other services were sought (e.g. NHS Direct)

Advanced medical facilities and highly trained paramedics continue to be used for alternative purposes opposed to time critical or life threatening emergencies, with ease of access and cultural expectation being significant underlying narratives. Improving the availability and communication links of other alternative services, in addition to the level of training to identify patients who require emergency assessment, could mean the avoidance of a large proportion of emergency unit attendances, with more appropriate use and utilisation of emergency facilities for their intended purpose.

Based on our study we propose a model for a multicenter study and we suggest an update of the EM and general practice training curricula, with emphasis on patients' medical education.


Samuel TYRRELL, Mahendra KAKOLLU, Samuel TYRRELL (Swansea, United Kingdom)

17:40
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AWC
Award Ceremony

Award Ceremony

Moderator: Colin GRAHAM (Director and Professor of Emergency Medicine) (Hong Kong, Hong Kong)