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Saturday 16 September
08:30
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A08
08:30 - 10:30

Complications of fillers

08:30 - 10:30 Illegal fillers : complications and treatment. John J. MARTIN (USA)
08:30 - 10:30 Nodular Complications: Problem-Oriented Case Analysis,. Hema SUNDARAM (USA)
08:30 - 10:30 Dangers of aesthetic procedures in wrong hands. Micheline CHALOUHI (LEBANON)
08:30 - 10:30 Complications: Staying Safe. Dalvi HUMZAH (West Midlands, UK)
08:30 - 10:30 Dangerous zones for your fillers injection. Patrick TREVIDIC (Paris, FRANCE), Gisella CRIOLLO LAMILLA (COLOMBIA)
08:30 - 10:30 Physico chemical Risk factors in Body Fillers Complications. Alain TENENBAUM (Lugano, SWITZERLAND)
08:30 - 10:30 Tip necrosis after injection of Calcium hydroxyapetatite. Chronology and analyze of the problem. David GRISHKYAN (RUSSIA)
08:30 - 10:30 How to manage filler complication ? Pierre NICOLAU (Barcelone, SPAIN)
08:30 - 10:30 All the things that can go wrong with dermal fillers.

Dermal fillers, specifically hyaluronic acid, is a very safe product in the hand of the experienced doctor. The more common this product gets, the more unexperienced physicians use this product. This leads, together with the usage of hyaluronic acid in regions not suitable for HA, to a growing number of serious complications.

This review of the current literature gives an overview of the worst complications reported in the last years, analizes the mistakes that were being made, gives tips and tricks how to deal with them and how to avoid them at all. 

Jan BALCZUN
Auditorium
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B08
08:30 - 10:30

Breast and Body Contouring

08:30 - 08:42 Tips for circumferential lipoplasty of the lower limbs: planning, contouring, and skin retraction. Alberto DI GIUSEPPE (Ancona, ITALY)
08:42 - 08:54 Liposuction for lipoedema. Robert BOONEN (Rotterdam, THE NETHERLANDS)
08:54 - 09:06 Protocol for gynecomastia using ultrasound-assisted lipoplasty under local anaesthesa. Peter PRENDERGAST (IRELAND)
09:06 - 09:18 Breast contouring with injectable radiofrequency. Gustavo LEIBASCHOFF (USA)
09:18 - 09:30 Mastopexy with cohesive gel silicone implants under local tumescent anaesthesia. Angelo REBELO (PORTUGAL)
09:30 - 09:42 Lipocontour: creating the perfect waist-hip ratio with combined lipoplasty and fat grafting. Hector DURAN (MEXICO)
09:42 - 09:54 Combined liposuction, tissue tightening and fat harvesting using a novel 1470nm diode laser technology. Shapira EYAL (ISRAEL)
09:54 - 10:06 4D high-definition lipo: the new era of body contouring. Thanasis ATHANASIOU (Athènes, GREECE)
10:06 - 10:18 Treatment of cellulite dimples: controlled subcision versus ultrasound dissection. Rolf BARTSCH (Vienna, AUSTRIA)
10:18 - 10:30 Q&A with panel.
Room 2
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C05
08:30 - 10:30

Aesthetic medicine and fine arts

08:30 - 08:50 Basic artistic rules - facial expressions. Sylvie WERKEN (FRANCE)
08:50 - 09:10 Makeup, relooking and postoperative advice. Ludovic LARTHOMAS (FRANCE)
09:10 - 09:25 Photoshop: how to distinguish true from false or how to deal with the patients' demands. Magali CONDE (FRANCE)
09:25 - 09:40 EBAME, artisic and expressive analysis of the face: a new form of artistic training in aesthetic medicine. Jamal DJOUDI (Vouneuil Sous Biard, FRANCE)
09:40 - 09:55 The Golden Number. Eric ESSAYAGH (Antibes Juan Les Pins, FRANCE)
09:55 - 10:10 Q&A.
Room 3
10:30
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P04
10:30 - 11:00

Morning break

11:00
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A09
11:00 - 13:00

Botulinum Toxin

11:00 - 11:15 From past to future. Mickael KANE (UK)
11:15 - 11:30 How the 3D anatomy can explain outcomes and pitfalls ? Patrick TREVIDIC (Paris, FRANCE)
11:30 - 11:45 Most recent protocols to optimize botulinum toxin. Charles VOLPEI (Nice, FRANCE)
11:45 - 12:00 Micro-meso-botulinum toxin: myth or reality? Practical update. Alessio REDAELLI (ITALY)
12:00 - 12:15 Botulinum toxin "around the eye". Eric SARFATI (Toulon, FRANCE)
12:15 - 12:30 Botulinum toxin in lower face. Frederic BRACCINI (Nice, FRANCE)
12:30 - 12:45 My tips and tricks to avoid complications. Nabila AZIB (MOROCCO)
12:45 - 13:00 Neurotoxin complications. John J. MARTIN (USA)
Auditorium
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B09
11:00 - 13:00

Medical Profiloplasty
The new paradigm for the best practice (forehead, nose, cheeks, lips, chin specifities)

11:00 - 13:00 Artistic approach : How to understand the ideal profile ? Jamal DJOUDI (Vouneuil Sous Biard, FRANCE)
11:00 - 13:00 Forehead : forehead and upper third : a harmonious balance.
11:00 - 13:00 Nose : Anatomic landmarks to make sure your procedure is safe. Gisella CRIOLLO LAMILLA (COLOMBIA)
11:00 - 13:00 Why the nose is an illusion ? What is the best technique to achieve perfection ? Frederic BRACCINI (Nice, FRANCE)
11:00 - 13:00 Ptosis correction by toxin. Eric SARFATI (Toulon, FRANCE)
11:00 - 13:00 My theory for a natural cheek. Fouad BELFKIRA (Lyon, FRANCE)
11:00 - 13:00 Must we choose between the bolus technique and the fan technique? Joelle HUTH (Périgueux, FRANCE)
11:00 - 13:00 Tips and tricks to obtain a natural lip. Christophe DESOUCHES (Marseille, FRANCE)
11:00 - 13:00 No touch lip enhancement. Eva GUISANTES (Barcelone, SPAIN)
11:00 - 13:00 Updates and techniques for lip rejuvenation and enhancement. Vincent WONG (London, UK)
11:00 - 13:00 Chin filling and management. Female versus male approach. Fabien GIAUSSERAN (Lille, FRANCE)
Room 2
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C06
11:00 - 13:00

Laser and new technologies

10min presentation +2 min questions
11:00 - 13:00 New revolutionary peeling. Jean Luc VIGNERON (St Paul, FRANCE)
11:00 - 13:00 Defocalized ultrasound and depressurized ultrascission. New techologies. Eric PLOT (FRANCE)
11:00 - 13:00 How to choose the right machines in esthetic medicine ? What works and what you should avoid. Philippe BLANCHEMAISON (Paris, FRANCE)
11:00 - 13:00 Correction of stretch marks with HiFU. Natalia LAPATINA (RUSSIA)
11:00 - 13:00 The Role of aesthetic techniques in reconstructive Head and Neck surgery. Stanislav IVANOV (RUSSIA), Inna LUCHKEVICH (ITALY)
11:00 - 13:00 Hybrid Laser Applications in Children - Clinical and Histological Results. Prof WILLITAL
11:00 - 13:00 Skin resurfacing in asian face. Lin WANG (Dalian, CHINA)
11:00 - 13:00 Combination of botulinum toxin and lasers in the Treatment of keloid and hypertrophic scars. Alena SAROMYTSKAYA (Volgograd, RUSSIA)
11:00 - 13:00 Hybrid Laser Applications in Children - Clinical and Histological Results. Günter WILLITAL (Münster, GERMANY)
Room 3
13:00
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P05
13:00 - 14:00

Lunch break

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L09
13:00 - 14:00

Industry Symposium

Room 3
14:00
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A10
14:00 - 16:00

Video Demo Devices

14:00 - 16:00 TBC. Noura LEBBAR (Milano, ITALY)
Auditorium
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B10
14:00 - 15:00

New laser technology

14:00 - 15:00 New approach in laser rejuvenation. Innovative solutions and techniques. Andreas ROUMBAS (CYPRUS)
14:00 - 15:00 The Effectiveness of Laser Therapy for Healings Diabetic Wounds & Burns. Farouk AL-WATBAN (SAUDI ARABIA)
14:00 - 15:00 Dealing with laser complications. Maria GONZALEZ (UK)
14:00 - 15:00 Laser and surgery combined therapy. Yann RENOULET (Düsseldorf, GERMANY)
14:00 - 15:00 How to manage hyper pigmented lesion with laser solutions ? Marie-Jeanne MINICONI (Nice, FRANCE)
Room 2
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C07
14:00 - 16:00

SOPREF Autumn Meeting
New trends and references in oculoplasty

14:00 - 16:00 Lower lid fillers vs blepharoplasty with fat repositioning. John J. MARTIN (USA)
14:00 - 16:00 New approach to the treatment of dark cicles withe hyaluronic acid.The "tear through ligament" , The key to success! Philippe BERROS (Monte Carlo, MONACO)
14:00 - 16:00 Blepharoplasty to upper eyelid. Eric SARFATI (Toulon, FRANCE)
14:00 - 16:00 Eyebrow position: Anatomical sighting, how to modify it? Eric SARFATI (Toulon, FRANCE)
Room 3
15:00
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B11
15:00 - 16:00

LED Session
Photobiomodulation : A Clinical glance : "A cellular cross talk"

15:00 - 15:15 New research to understand the Dermo Epidermal Cross –Talk: Photobiomodulation ,Bioinduction , Mecano- transduction. Pierre-Alexis GRIMAUD (Paris, FRANCE)
15:15 - 15:30 Light Emitting Diode Red Light Impact on Cellular Signaling and Function in Skin Fibrosis. Jared JAGDEO (USA)
15:30 - 15:45 Preparing the Skin or repairing the Skin? Changes in cell signalization in function of the sequence of LED Delivery, before or after an aesthetic procedure. Susanne HAUSDORFER (BELGIUM)
15:45 - 16:00 Acne : A Vicious signaling circle ? Linda FOUQUE (Nice, FRANCE)
Room 2
16:00
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P06
16:00 - 16:30

Afternoon break

16:30
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A11
16:30 - 17:30

Video Demo Devices

16:30 - 17:30 TBC. Noel SCHARTZ (Paris, FRANCE)
Auditorium
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B12
16:30 - 17:30

Cosmetic and nutrition

16:30 - 16:38 Learning how to decipher the composition of the products that we prescribe. Régis MARTIN (Paris, FRANCE)
16:38 - 16:46 Answers to the patients' frequently asked questions. Michel LE MAITRE (Caen, FRANCE)
16:46 - 16:54 Anti-age cosmetology. How to choose the right active ingredients ? Audrey-Geneviève TARPIN-LYONNET (Marseille, FRANCE)
16:54 - 17:02 Masked allergens. Jean-Romain MANCIET (Neuilly Sur Seine, FRANCE)
17:02 - 17:10 ANTI-AGEING EFFECT OF PURE SILK TISSUE WITH ULTRA-FINE SILVER NANO-COATING CORRELATION BETWEEN CLINICAL AND BIOLOGICAL RESULTS ESTABLISHED WITH A SURVIVING HUMAN SKIN MODEL.

Objectives of the  studies

The anti-ageing effect of pure silk (100%) tissue with ultra-fine silver (999.9) nano-coating (Mrs KUDRINA as inventor) was evaluated on healthy volunteers and with

a biological evaluation on an experimentally aged human skin model.

 

Methods

The first clinical study on 20 volunteers allowed to evaluate the anti-ageing efficacy of an eye mask after 1 night application on bags under eyes, crow's foot wrinkles, dark eye-rims and hydration.

The second study on 13 volunteers was conducted after 1 month application of a helmet mask to evaluate skin glow and skin density.

For the biological evaluation, silk tissue nano-coated with silver was applied on skin fragments experimentally aged by UV (A and B) and maintained in survival during 14 days.

 

Results

The first clinical study has shown the efficacy of 1 night application of the eye mask, with a significant decrease (23.5%) of bags under eyes (dermatological scoring), of crow's foot wrinkles by 6.6 % (profilometric evaluation by image analysis), of dark eye-rims by 3.2 % (chromometric evaluation) associated with a significant increase of hydration around eyes by 4.1% (corneometric measurement).

 

The second clinical study, after 1 month of daily use of the helmet mask, has revealed a significant increase of skin glow by 49% (dermatological scoring) and of skin density by 8.5 % (echographic measurement).

 

The application of silk tissue nano-coated with silver on human skin fragments maintained in survival allowed to obtain a significant increase by 60% of epidermis renewal (mitotic index increased) and of  glycosaminoglycans rate (histologic analysis) associated with a significant decrease of free radicals by 13% (H2O2 assay).

 

 

Conclusion

            In our dermatological experience, it is the first time we obtained a complete correlation between clinical and biological anti-aging effect of a cosmetic product:

 

-       Anti-ageing effect with crow's foot wrinkles decrease in clinical environment correlated with mitotic index increase and free radicals decrease observed in the biological skin model.

-       Hydration increase around eyes correlated with glycosaminoglycans increase in the biological skin model.

-       Firmness and cutaneous density increase correlated with collagen synthesis in the biological skin model.

 

Sylvie BOISNIC, Zinaida KUDRINA
17:10 - 17:18 Co-drugs in cosmetics, in particular vitamin C and retinol and their uses/applications as new transcutaneous vectors. Alfred MARCHAL (Waterloo, BELGIUM)
17:18 - 17:26 Hyperacute serum - a novel blood derivative that outperforms PRP in supporting cell proliferation and adipogenesis from MSCs.

Introduction

Fat tissue, due to its high concentration of pluripotent stem cells, has a role in aesthetic medicine and reconstructive surgery. However, poor survival of the transplanted cells still limits the usefulness of this material in regenerative medicine. Several studies indicated that platelet rich plasma (PRP) may improve adipose tissue viability due to its growth factor content. However, pro-inflammatory agents such as fibrin and leukocytes are also present in PRP which are not desired in these indications. The present study aimed to investigate the effects of hyperacute serum, a novel cell- and fibrin-free blood derivative on the adipogenic lineage in vitro.

Methods

Metabolic activity and proliferation rate of human mesenchymal stem cells (MSCs) cultivated in media supplemented with three types of serum additives (fetal calf serum (FCS), human PRP or hyperacute serum). Hyperacute serum was isolated from glass-activated platelet rich fibrin within 10 minutes of blood drawing to prevent the propagation of inflammatory cascades.  Cell proliferation was determined using a tetrazolium assay. Adipogenesis was evaluated in standard and pro-adipogenic media  and tested by oil red staining, triglyceride content and expression of specific genes. Adipogenic and adipokine proteins in the sera were measured by multiplex ELISA assays.

Results

Proliferation of MSCs was supported by both FCS and hyperacute serum in a time-dependent manner, but surprisingly, PRP had a much weaker effect (change in proliferation rate after 5 days relative to metabolic activity on day 0 - FCS : 5.4 fold, hyperacute serum : 5.8, serum free 1.9, PRP 3.0 p<0.05). Lipogenesis was only observed in groups with adipogenic differentiation medium, with hyperacute serum showing a significantly stronger effect than PRP. This was confirmed by intensive accumulation of lysochrome dye in lipid droplets, higher triglyceride concentration and elevated expression of specific adipogenic genes. Interestingly it was also observed that in hyperacute serum group the production of COL1 was highly upregulated. Measurement of lipogenic proteins in the sera revealed,  that both PRP and hyperacute serum are abundant in them, PRP also contains anti-adipogenic factors which explains its weaker and less reliable effect.

Conclusion

Hyperacute serum provides more robust support than PRP in MSC proliferation as well as lipogenic differentiation, indicating that it may be a better adjuvant in fat grafting procedures.

Olga KUTEN, Zsombor LACZA, Melinda SIMON, Stefan NEHRER
Room 2
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C07bis
16:30 - 18:30

SOPREF Autumn Meeting - COPIE
New trends and references in oculoplasty

Room 3
17:30
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A12
17:30 - 18:30

Update on fillers

17:30 - 18:30 Rheology and behavior of hyaluronic acids. How to make the right choice? Philippe PICCERELLE (Marseille, FRANCE)
17:30 - 18:30 Anatomy of dangerous facial areas with fillers. Patrick TREVIDIC (Paris, FRANCE), Gisella CRIOLLO LAMILLA (COLOMBIA)
17:30 - 18:30 The causes of complications with fillers. How to manage them? Pierre NICOLAU (Barcelone, SPAIN)
17:30 - 18:30 Fillers without BDDE, is this possible ? Jean Luc VIGNERON (St Paul, FRANCE)
17:30 - 18:30 What is the ideal Facial Volumetry ? Charles VOLPEI (Nice, FRANCE)
17:30 - 18:30 Less is More. New concept in the use of fillers. Frederic BRACCINI (Nice, FRANCE)
17:30 - 18:30 Anatomic, Scientific and Clinical Rationale for Layered Volumetry,. Hema SUNDARAM (USA)
17:30 - 18:30 Toxin alternatives and their efficacy. Vincent WONG (London, UK)
Auditorium
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B13
17:30 - 18:30

Non surgical threads rejuvenation

17:30 - 18:30 The biomechanics of suspensory threads. Pierre NICOLAU (Barcelone, SPAIN)
17:30 - 18:30 My experience in the use of cone threads. Paola ROSALBA RUSSO (Milan, ITALY)
17:30 - 18:30 "Easy jawlift" with threads. New technique. Jean Luc VIGNERON (St Paul, FRANCE)
17:30 - 18:30 One-stitch facelift : indications and technique. Peter PRENDERGAST (IRELAND)
17:30 - 18:30 Combined use is optimal for safe, effective thread placement. Maged HAJ-YOUNES (Barcelone, SPAIN)
17:30 - 18:30 Permanent tightening threads. How they have become a true lifiting procedure. Jean-Paul FOUMENTEZE (Cannes, FRANCE)
17:30 - 18:30 Thread lifting with polycaprolactone threads (Happy Lift). Vincent WONG (London, UK)
Room 2