Saturday 23 September
08:00

"Saturday 23 September"

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PC2
08:00 - 18:00

Emergency Medicine Core Competences: Survival Skills for You

Animators: Veronique BRABERS (Emergency Physician) (Animator, MOL, Belgium), Caroline HÅRD AF SEGERSTAD (Senior consultant) (Animator, Ystad, Sweden), Nikolas SBYRAKIS (Consultant Emergency Physician) (Animator, Heraklion, Greece)
Pre-Course Directors: Eric DRYVER (Consultant) (Pre-Course Director, Lund, Sweden), Martin FANDLER (Consultant) (Pre-Course Director, Bamberg, Germany, Germany), Gregor PROSEN (EM Consultant) (Pre-Course Director, MARIBOR, Slovenia)
MC-3-2
08:30

"Saturday 23 September"

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PC4
08:30 - 17:30

Disaster Medicine

Animators: Pr Pinchas HALPERN (department chair) (Animator, Tel Aviv, Israel, Israel), Hayato KURYHARA (Animator, Italy), Matthieu LANGLOIS (medecin) (Animator, Paris, France), Luca RAGAZZONI (Scientific Coordinator) (Animator, Novara, Italy), Antoine TRAN (MCU-PH, médecin des urgences pédiatriques) (Animator, Nice, France), Benoît VIVIEN (Adjoint du Chef de Service du SAMU de Paris, Responsable du SAMU Pédiatrique Régional IDF) (Animator, Paris, France)
Pre-Course Directors: Massimo AZZARETTO (Medico Specialista) (Pre-Course Director, Lugano, Switzerland), Pr Francesco DELLA CORTE (Head of Emergency Department) (Pre-Course Director, Novara, Italy), Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Pre-Course Director, Besançon, France)
ROOM 1

"Saturday 23 September"

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PC3
08:30 - 18:00

Advanced Paediatric Emergency Care (APEC)

Animators: Dr Rodrick BABAKHANLOU (M.D. M.Sc.) (Animator, Edinburgh), Dr Thomas BEATTIE (Senior lecturer) (Animator, Edinburgh, United Kingdom), Silvia BRESSAN (Moderator) (Animator, Padova, Italy), Liviana DADALT (Animator, Italy), Santiago MINTEGI (Section Head. Pediatric Emergency Department) (Animator, Bilbao, Spain), Niccolò PARRI (Attending Physician) (Animator, Florence, Italy), Itai SHAVIT (Pediatric Emergency Physician) (Animator, Haifa, Israel), Pr Hezi WAISMAN (Director, Dept. of Emergency Medicine) (Animator, Petach-Tikva, Israel), David WALKER (Speaker) (Animator, New York, NY, USA)
Pre-Course Director: Said HACHIMI-IDRISSI (head clinic) (Pre-Course Director, GHENT, Belgium)
ROOM 2
09:00

"Saturday 23 September"

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PC1
09:00 - 17:00

Pre-Course Ultrasound Beginner

Animators: Zeki ATESLI (Animator, BRIGHTON, United Kingdom), Erol ERDENUN (Animator, Turkey), Rip GANGAHAR (Consultant) (Animator, OLDHAM), Hani HARIRI (Animator, Besançon, France), Beatrice HOFFMANN (Animator, Boston, USA), Dr Nicolas LIM (Consultant Emergency Medicine) (Animator, Singapore, Singapore), Najib NASRALLAH (PHYSICIAN) (Animator, SHEFAMER, Israel), Gregor PROSEN (EM Consultant) (Animator, MARIBOR, Slovenia), Arthur ROSENDAAL (Emergency Physician) (Animator, Rotterdam, The Netherlands), Omer SALT (ASSISTANT PROFESSOR) (Animator, EDIRNE, Turkey), Prem SUKUL (EP) (Animator, Rotterdam, The Netherlands), Dr Joseph WOOD (Ultrasound instructor) (Animator, Phoenix, Arizona, USA)
Pre-Course Directors: James CONNOLLY (Consultant) (Pre-Course Director, Newcastle-Upon-Tyne), Michael LAMBERT (not sure what this is for?) (Pre-Course Director, Burr Ridge, USA), Hein LAMPRECHT (Pre-Course Director, South Africa)
09:00 - 17:00
09:00 - 17:00
MC-2

"Saturday 23 September"

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PC6
09:00 - 17:00

SafeER PSA - Procedural sedation and analgesia for Emergency

Animators: Meys COHEN (Emergency Physician) (Animator, Leiden, The Netherlands), Harald HENNIG (Emergency Physician) (Animator, Neumarkt i.d.OPf., Germany), Eda OKATAN (emergency physician) (Animator, The Netherlands, The Netherlands), Mischa VEEN (Animator, Leiden, The Netherlands), Arjan VOS (ED physician) (Animator, Amersfoort, The Netherlands), Roy WELSING (Emergency Physician) (Animator, Amersfoort, The Netherlands)
Pre-Course Director: Christian HERINGHAUS (Emergency Physician) (Pre-Course Director, Leiden, The Netherlands)
ROOM 7

"Saturday 23 September"

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PC5
09:00 - 17:00

Non-Invasive Ventilation

Animators: Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Animator, Besançon, France), Roberta MARINO (Chief of Borgosesia Hospital ED) (Animator, Vercelli, Italy), Patrick PLAISANCE (Head of Department) (Animator, Paris, France)
Pre-Course Directors: Roberto COSENTINI (Head of Emergency Medicine) (Pre-Course Director, BERGAMO, Italy), Paolo GROFF (Director) (Pre-Course Director, Perugia, Italy)
TRACK F KOKALI
Sunday 24 September
08:30

"Sunday 24 September"

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POSTERS
08:30 - 17:40

E-POSTERS DISPLAY
e-posters displayed during the entire congress from 24 to 27 September

08:30 - 17:40 #10869 - 'Myth Of Antiobiotic' - An Observational Study.
'Myth Of Antiobiotic' - An Observational Study.

Background : 
Majority of chest injuries will result in patients sustaining hemothorax, pneumothorax or both. About 80% are managed simply by putting a chest drain. One of the common complication is infection. Use of prophylactic antibiotic in many surgical procedures is common practice, but the use of prophylactic for chest drain insertion is not clear.There are no current guidelines available on such issue .BTS guidelines did mentioned that we should consider prophylactic antibiotic in chest trauma needed chest drain but not recomended .Routine use of antibioctic is contrversial.
Aim :
To find out the rate of infection in patients requiring chest drain insertion following chest trauma .
Methods: - 
Retrospective study conducted in the busy Emergency Department of birmingham from January 2013- March 2014
Results: In 15 months 55 patients had chest drain. Only 36 patients had full hospital notes available so 36 patients included for this observational study ..
Male patients were 26 and female were 10 in numbers.
Age distribution of patients between 18 – 20 years = 6 between 20-50 years =11 and between 50-90years = 19. Depending on mechanism of injury CT chest was done as either part of trauma CT or isolated CT chest on all 36 patients Common findinge were Multiple rib fracture,lung contusion,hemothorax and pneumothorax.
Full aseptic technique was practiced only on 21 occasions.
Consultants inserted 10 drains, 20 drains were inserted by ST-4 and above including speciality doctors .6 drains were inserted by junior doctors mixed grade under supervision.
Mechanism of injury: 17 patients (47 %) with blunt chest injury, 19 (52.7%) patients with penetration injury inlcuded stab wounds, gun shot wounds, accidental penetrating injury fall on sharp objects.
17 patients with penetrating injuries, needed chest drain had antibiotic and only 2 patients have infection (12 %)
19 patients with blunt chest injuries ,had chest drain because of hemothorax, pneumothorax or both, 8 patients (42 %) developed infective complication, and infection includes 6 pneumonia, 1 local wound infection and 1 empyema .
Conclusion: 
This study showed the increase rate of infection in patients with chest drain insertion without antibiotic,so administrating prophylactic antibiotics in thoracic trauma needed chest drain insertion can be beneficial which deacrease the mortality and morbidity.

Hamid ILYAS, Mehtab KHAN (wolverhampton, ), Obaidullah ZAFAR, Abdul JALIL
08:30 - 17:40 #11721 - A "glue sniffer" teenager with anuric renal failure and hepatitis.
A "glue sniffer" teenager with anuric renal failure and hepatitis.

Background and Objectives: "Inhalant abuse" is a common form of volatile drug abuse throughout the world especially in developing countries. This substance mainly contains toluene.  Acute toluene inhalation produces a biphasic response with an initial central nervous system (CNS) excitation followed by CNS depression as well as various metabolic alterations. Chronic inhalational abuse is associated with muscular weakness, gastrointestinal symptoms, renal and hepatic injury. In this report,  we describe an adolescent presented with jaundice, nausea, vomiting and reduced urine output who developed severe acute renal/hepatic damage due to abuse of gas products.

Case report: A 16-year-old boy admitted to the emergency department with a history of nausea, vomiting,  jaundice and reduced urine output for three days. There was no history of previous illness. He begun to practice "glue sniffing" eight months ago and he increased the amount of inhalant in the last two months. He had sniffed approximately 50 ml/day (one tube) of adhesive (bally) during the previous two days before his admission to hospital.  Upon arrival to the emergency department, he was drowsy with Glasgow coma scale (GCS) 13, mildly dehydrated, his pulse and blood pressure were 90/min and 124/79 mm Hg, respectively. He also had yellowish staining of the sclera and conjunctival hyperemia. Laboratory assessment revealed the serum creatinine was 9,6 mg/dL, urea 178mg/dL, aspartat aminotransferase 778 U/L, alanine aminotransferase 1681 U/L, total bilirubin 4.3 mg/dL, direct bilirubin 2.92 mg/dL. The patient was admitted to the pediatric intensive care unit due to renal, hepatic damage and encephalopathy. Since toluene is the main toxic agent involved in glue sniffing which is metabolized to hippuric acid, the present case was treated with continuous hemodiafiltration, plasma exchange and conservative therapy to eliminate hippuric acid. The jaundice gradually disappeared, he had complete recovery of renal/hepatic functions in ten days.

Conclusion: “Glue sniffing” should be included in the differential diagnosis of any teen patient presenting with unexplained acute hepatorenal failure especially in patients who does not have any environmental and exposure.


Dr Ali YURTSEVEN (İzmir, Turkey), Caner TURAN, Pınar YAZICI ÖZKAYA, Bulent KARAPINAR, Eylem Ulas SAZ
08:30 - 17:40 #11633 - A 4-step approach to reduce door-to-CT time in major trauma.
A 4-step approach to reduce door-to-CT time in major trauma.

Introduction

In major trauma care, computed tomography (CT) has become the golden standard for diagnostic workup. Rapid access to CT facilitates the diagnosis of life-threatening injuries. Door-to-CT time is a crucial determinant of survival in major trauma patients. Getting patients to CT within 30 minutes after arrival at the emergency department (ED) is an important quality indicator in early clinical care. Therefore, a short distance between the CT scanner and the trauma room (<50 m) is recommended. As not every hospital has a CT scanner in close proximity of the trauma room, other solutions to reduce the door-to-CT time should be found.

 

Materials and Methods

This was an observational, retrospective cohort study in a university emergency department where the CT scanner is not located in the ED. Over a period of 18 months (01/10/2015 - 31/03/2017), 241 major trauma patients received CT. The time from patient arrival in the hospital to first image on the CT table was registered. Stable trauma patients transferred from another hospital were not included. During the study period, we introduced four changes in the initial management to reduce door-to-CT time: increasing awareness of the trauma team (introduced 01/2016), training to increase trauma team efficiency (introduced 09/2016), use of a standardised immobilisation and transfer protocol (introduced 10/2016) and marking of the intravenous contrast access line (introduced 11/2016). No other changes were made during the study period: the distance to CT, the trauma alert procedure and the trauma protocol did not change. We compared door-to CT time between the first and the last trimester of the study period. Continuous variables are reported as mean (standard deviation, range) and analysed with the Unpaired Student T-test (equal variances assumed). Proportions were analysed with the Chi Square test.

 

Results

The mean door-to-CT time was 31 minutes (11, 17-55) in the first trimester and 21 minutes (10, 8-58) in the last trimester, a reduction of 32% (95% confidence interval 5-16 min). The proportion of patients with a door-to-CT time <30 minutes was 10/21 (48%) and 46/56 (82%), odds ratio 5.06 (95% confidence interval 1.69-15.14).

 

Discussion and conclusion

A 4-step approach significantly reduced door-to-CT time and increased the chance to get patients from arrival at the emergency department to CT within 30 minutes. This strategy may be helpful, especially when the CT scanner is not closely located to the trauma room.

 


Kristof SCHOETERS (Antwerp, Belgium), Philip VERDONCK, Sabine LEMOYNE, Koenraad G. MONSIEURS
08:30 - 17:40 #11587 - A case of Local Anesthetic Systemic Toxicity induced by lidocaine and treated successfully with lipid emulsion in the emergency department.
A case of Local Anesthetic Systemic Toxicity induced by lidocaine and treated successfully with lipid emulsion in the emergency department.

Introduction: In the emergency department (ED), local anesthetics are often used during various procedures. Local Anesthetic Systemic toxicity (LAST) leads to potentially fatal adverse events. Although the number of reports showing the effectiveness of lipid emulsion therapy for LAST has been increasing, the indication of its use is unclear. We present a case of LAST that was induced by caudal epidural anesthesia and treated successfully with lipid emulsion therapy in the ED. 

Case:A 58-year-old woman presented to the ED with severe low back pain. Since oral analgesic (loxoprofen 60mg) was not effective, caudal epidural anesthesia was performed. Immediately after 20 milliliters of 1% lidocaine was administered, the patient complained of systemic numbness, with rapid progression to an altered mental states. The blood pressure was 134/70 mmHg, the pulse 78 beats per minute, the respiratory rate 24 breaths per minute, and oxygen saturation 95%. We suspected lidocaine toxicity and treated with intralipids. After 90 milliliters of 20% intralipids was rapidly administered, the patient gradually regained consciousness. The continuous infusion of intralipids following initial infusion was not performed. After that, the patient was hospitalized for observation, but there was no recurrence of the symptoms.

Conclusion: The number of reports on LAST has been increasing, but there are few reports from the ED setting. Emergency physicians should be aware of LAST because of its severity. Intravenous lipid emulsion therapy can be the significant treatment in anesthetic overdoses. Although the severity-based criteria of administration is not standardized, lipid emulsion therapy is considered effective for patients with neurological symptoms.


Kotaro TAKEBE (Kyoto, Japan), Tasuku MATSUYAMA, Yosuke MAKINO, Yuki MIYAMOTO, Makoto WATANABE, Yoshihiro YAMAHATA, Bon OHTA
08:30 - 17:40 #11296 - A case of paradoxical embolism affecting the celiac, superior mesenteric and renal arteries.
A case of paradoxical embolism affecting the celiac, superior mesenteric and renal arteries.

Paradoxical embolism, also known as crossed embolism, happens when an embolus from venous circulation passes through an intracardiac shunting in the arterial system, causing ischemic  events, with different clinical  manifestations, depending on the artery embolized.

A 77 year old woman with a previous history of arrhythmia and depression was transferred to the E.D. complaining about abdominal pain in the epigastrium and LLQ, fatigue and malaise the last 2 days. She also mentioned back pain for the previous 2 months.

Her vital signs were BP:75/30 HR:99 RR:22. The clinical examination revealed an abdomen soft in palpation with pain in the epigastrium and the left lower quadrant  and good bowel sounds.

After she responded to the initial resuscitation with fluids and inotropes, she was transferred to the radiology department for a thorax-abdomen CT scan. The CT showed thrombosis of the superior mesenteric artery, celiac artery, inferior mesenteric  and the renal arteries. A bilateral pulmonary embolism was additionally diagnosed .

The patient was admitted to the I.C.U and underwent thrombolysis with alteplase. She was gradually improved. She remained at nil per os until the 5th day of hospitalization. Her clinical and laboratory status was returned to normal with no tenderness in the abdomen and oral feeding started.

Further examination with triplex of the venous system, heart ultrasound, CT scan and blood test for cancer markers was performed. There was a deep vein thrombosis  of the right common femoral vein and right deep femoral vein  found. The patient also had a patent foramen ovale. The cancer markers were within physiological ratio and the CT showed amelioration of the P.E., and also fewer and smaller deficits in the lumen of splanchnic arteries, mainly in peripheral branches. The splenic parenchyma was seen with multiple infarcts.

We came to the conclusion that the arterial embolisms with a concomitant DVT and PE in this patient  are an example of paradoxical embolism, taking into consideration  the right to left shunting through an intracardiac communication that the heart ultrasound revealed.

The diagnosis of paradoxical embolism remains very challenging. In order to confirm it a thrombus must be detected in an intracardial defect (in ultrasound or autopsy).

In general, it has a good prognosis. The complications depend on the site of infarction. It can be treated by medication, surgery or a combination of these.


Paraskevi KARONA (Chania, Greece), Kyriakos GRAMMATIKOPOULOS, Georgios PETRAKIS, Athina ANAGNOU, Eleni TSAKIRAKI, Dimitrios VOUTSINOS, Spyridon KAVROCHORIANOS, Emmanouil CHARITAKIS, Krystallenia KAFKALA, Nikolaos KATSOUGKRIS, Konstantina PAPADOPOULOU, Alexandros PAPADOMICHELAKIS, Miltiadis KASTANAKIS
08:30 - 17:40 #11933 - A case of severe salmonellosis in a family.
A case of severe salmonellosis in a family.

Introduction: Non-typhoidal Salmonellae are an important cause of infectious diarrhoea world-wide, especially in children. In the absence of immunodeficiency, disease is usually self-limiting. However, severe salmonellosis is possible in case of higher infective dose ingestion and virulency especially in host with impaired defensive mechanisms including reduced gastric acidity and immune response. Children are at higher risk of manifesting severe salmonellosis almonelosis especially at younger age due to lack of defensive mechanisms mentioned above. We present a case of severe salmonellosis in a family. 

Case presentation: Two sisters at the age of 8 and 11 years were admitted to Emergency department (ED) because of febrile diarrhoea and somnolence. Their 4-year-old brother was found dead at home the same morning. At the time of admission, older sister had between 6 and 10 watery stools  without pathological impurities and signs of severe dehydration accompanied by encephalopathy. High inflammatory markers and neutrophilia suggested development of systemic inflammatory response syndrome. Hemocultures were negative.  Salmonella enteritidis was positive in stool culture. She was treated in intensive care in other clinic where parenteral rehydration and antimicrobial therapy with ceftriaxone followed by cefotaxime  was administered. During treatment she developed hypertension and bilateral pleural effusions. Additional evaluation revealed acute tubular damage and was treated with antihypertensives. The disease course was complicated by Clostridium difficile colitis. A  8-year-old sister was hypotensive at the time of admission to ED. Hemocultures came negative. However, Salmonella enteritidis was positive in stool culture as well. Antimicrobial therapy with ceftriaxone and parenteral rehidration was administered. Sisters recovered without sequellas.

Conclusion: Severe salmonellosis is potentially life threatening disease especially in children at younger age.


Tena TRBOJEVIĆ (Zagreb, Croatia), Lea MIKLIC
08:30 - 17:40 #11187 - A case of Wheat Dependent Exercise Induced Anaphylaxis (WDEIA).
A case of Wheat Dependent Exercise Induced Anaphylaxis (WDEIA).

TITLE:A case of Wheat Dependent Exercise Induced Anaphylaxis (WDEIA)

INTRODUCTION:  Food-dependent, exercise-induced anaphylaxis (FDEIAn) is a disorder in which anaphylaxis occurs only in association with physical exertion and only if a specific food to which the patient is sensitized is eaten in the pre-exercise period; Neither the food(s) alone nor exercise alone is sufficient to induce a reaction. There are several varieties of food can trigger this kind of anaphylaxis such as, milk, peanut, wheat, fish, pork, and meat.

METHODS:  A 39-year-old female presented to the ED with skin rash on her face and upper limbs along with pins and needles following exercise.  She felt nauseous and very unwell during exercise and skin rash started to appear on her face and upper limbs along with swelling over her eyelids, she did not report any shortness of breath. On examination, she had a generalised urticarial rash and was hypotensive. She vomited once in the ED. She had a past medical history of an allergic reaction to ibuprofen. Emergency intervention was done per protocol and patient was stabilized. She was discharged home after a period of observation and her symptoms had settled fully. Because exercise was the only obvious triggering factor in the history and she had no other specific known allergies, we sent her to immunology clinic for follow-up.

RESULTS: The patient was diagnosed as having wheat dependent, exercise-induced anaphylaxis (WEDIA) by the Immunology Team based on her IgE and Omega 5 Gliadin levels.

CONCLUSION: Many cases of allergy and anaphylaxis present to the Emergency Department without an obvious definitive cause. With an accurate history, clinical sense and challenge tests the diagnosis can be made and appropriate steps taken to minimise the risk of recurrence.


Dr Khalid ABDALLA (Sligo, ), Aymen AHMED, John O'DONNELL
08:30 - 17:40 #11317 - A CASE REPORT OF AORTIC DISSECTION: THE SILENT KILLER.
A CASE REPORT OF AORTIC DISSECTION: THE SILENT KILLER.

Aortic dissection is a rare and lethal condition that is difficult to manage. Therefore, combination of early detection, fast response and accurate diagnosis are crucial for better survival rate. This case discusses on atypical presentation of aortic dissection which resulted in haemodynamic instability. A 34-year-old man presented to the Emergency Department (ED), Klang Hospital for lethargy, breathing difficulty and feeling unwell for the past 5 days. A week prior attending the ED, he went to seek treatment at a private medical center for similar complaint. However, there was no significant finding noted from the physical examination and basic blood investigation done. On arrival, he was conscious and appear lethargic. The sclera was pink, extremities were cold and capillary filling time was 2 seconds. His vital signs were as follow; blood pressure 80/64 mmHg; heart rate 110 bpm with poor pulse volume; respiratory rate 28 breath per minute;  oxygen saturation 98% under room air and afebrile. There were no radio-radial delay or radio-femoral detected. ECG was immediately taken which showed sinus tachycardia. His chest radiograph revealed wide mediastinum. Bedside ultrasound was performed to investigate the underlying cause of hypotension. Based on bedside echocardiography, presence of pericardial effusion with tamponade effect was noted. An emergency transcutaneous pericardiocentesis was performed to release the tamponade effect. 100ml of fresh blood was withdrew during the procedure. His blood pressure temporarily improved following the procedure. Subsequently the patient developed one episode of generelized tonic clonic seizure in which aborted spontaneously. He was then intubated for airway protection. CT thorax was requested and result showed dissecting aortic aneurysm with possible leak to the pericardium. The patient was admitted to intensive care unit (ICU) as he was not stable for transfer to cardiothoracic unit center. Unfortunately, the patient was succumbed after 48 hours at the ICU.

The non-specific symptom found in this patient may lead physician to a wrong diagnosis. This patient had no typical presentation of dissecting aorta such as tearing-like back pain or chest pain upon presentation. In this case, the only positive finding identified for his condition was hypotensive. Therefore, it is very important to rule out the cause of hypotensive retrospectively. Bedside ultrasound or echocardiography may differentiate causes of shock such as cardiogenic, hypovolemic or distributive in origin. Emergency transcutaneous pericardiocentesis is a life saving procedure, therefore it is compulsory for emergency medical practitioners especially in emergency department to be able to perform the procedure confidently whenever indicated. The procedure may assist in achieving better cardiac output temporarily whilst waiting for more definitive treatment to take over.   


Mohd Azmani SAHAR (Kuala Lumpur, Malaysia), Norsham JULIANA
08:30 - 17:40 #11385 - A Case Series on Isolated Lead aVR ST-Segment Elevation Clinical Significance and Outcome.
A Case Series on Isolated Lead aVR ST-Segment Elevation Clinical Significance and Outcome.

ABSTRACT: Background:One of the least significant leads on a 12-lead electrocardiogram is the augmented right lead (aVR), as it is not as specific compared to the other leads. In this case series, the value of lead aVRis highlighted. Three cases of aVR ST segment elevation on 12-lead electrocardiogramare described, with the end outcome of demise of all three patients. The importance of immediate revascularization is described to improve prognosis in this group of patients. Objectives: This case series aims to primarily present under-reported cases of isolated aVR ST-segrment elevation myocardial infarction (STEMI), their course and outcome.  More specific aims are to identify the criteria in determination of isolated aVR STEMI, know its clinical significance, and determine appropriate management for patients with this ECG finding. Method: A short review of previous studies, case reports, articles and guidelines from 2011-2016 was done.  The author reviewed available literature, sorted out those that proved to be significant for the presented cases, and described them in conjunction with the aforementioned cases. Findings: Based on the limited information on these rare or under-reported cases, it was found that isolated aVR STEMI had a poorer prognosis that led to significant mortality and morbidity of patients.  The significance of aVR ST-elevation was that of an occlusion of the left coronary artery or a severe three-vessel disease in the presence of an Acute Coronary Syndrome.    Guidelines from American Heart Association/American College of Cardiology Foundation in 2013 already recognized ST-elevation of lead aVRin isolation as a STEMI; hence, recommended that patients with this particular ECG finding should undergo reperfusion strategies to improve prognosis. Conclusion: The indispensability of isolated aVR ST-segment elevation on ECG should alert physicians, especially Emergency physicians, to the high probability of Acute Coronary Syndrome with a very poor prognosis.  If this group of patients is not promptly managed, demise may ensue, with cardiogenic shock as the most probable cause.  With this electrocardiogram finding, physicians must be quick to make clinical decisions to increase chances of survival of this group of patients.


Fae Princess BERMUDEZ (Quezon City, Philippines)
08:30 - 17:40 #11473 - A Catastrophic Antiphospholipid Syndrome in a young woman with Multiorgan thrombosis and fulminant multiorgan failure.
A Catastrophic Antiphospholipid Syndrome in a young woman with Multiorgan thrombosis and fulminant multiorgan failure.

Introduction :

Catastrophic antiphospholipid syndrome (CAPS) is an unusual form of presentation of antiphospholipid syndrome with a poor prognosis. Early diagnosis and treatment are necessary. Acquired thrombotic and thromboembolic disorders may be presented initially with symptoms and signs of acute ischemia or organ dysfunction that will lead many of these patients to seek care in the emergency department. 

Case Report :

We reported a case of a 33-year-old female patient without significant medical history admitted to the emergency department with sudden onset abdominal pain, vomiting and dyspnea. She was managed conservatively, but her symptoms progressed with eventual multi-organ failure. Laboratory tests showed autoimmune anemia at 10 g/dL, and thrombocytopenia at 10,000/mm3. The CRP was measured at 144 mg/L, and the creatinine clearance at  30 ml/ min. The thoracic and abdominal CT scan showed multiple venous and arterial thrombosis: Inferior vena cava, Hepatic veins and pulmonary artery with multiple focal hypo dense liver, pancreas and spleen lesions corresponding to micro infarctions. The patient presented a respiratory distress leading to intubation and mechanical ventilation. The evolution was marked by the death after 12 hours.

Conclusion :

CAPS is a medical emergency which requires early identification and aggressive management to improve outcomes. Clinicians need a heightened awareness of this disease state when managing patients with acute thrombosis of multiple organs with no clear etiology.

 


Rim HAMAMI (Tunis, Tunisia), Ghofrane BEN JRAD, Ines GUERBOUJ, Olfa DJEBBI, Bassem CHATBRI, Mehdi BELLASSOUED, Khaled LAMINE
08:30 - 17:40 #11610 - A COMPLICATED BREAKFAST.
A COMPLICATED BREAKFAST.

54 years old male, with a medical history of benign esophageal stricture since 2007 treated with endoscopic dilation (no more since 2011 by recurrency), presented in the emergency room with retrosternal pain since breakfast. Habitually he eat liquid or crushed food but that morning he eated  bread and omelet of sausage , after hearing a noise, starting pain even swallowing,  foreign body sensation and a vomit only with blood content. Denied taking antiinflamatory agents previous days.

In the hospital blood test, venous blood gases, EKG and chest Rx is requested that presented normal results, but pain persists in spite of endovenous analgesia. Because of this fibroscopy and endoscopy is performed searching foreign body. No foreign body is seen in fibroscopy and in endoscopy is seen an esophageal stricture impassable 20cm from dental arcade. The do not dilate it.

After endoscopy patient have fever and increases pain, requiring intravenous morphine, so that thoracic CT with oral and intravenous iodinated contrast is performed. In CT  is observed extravasation of contrast through continuity solution about 8cm of origin of the esophagus which is associated with pneumomediastinum, compatible with esophageal perforation and secondary mediastinitis at the vertebral body height D3. There isn’t foreign body.

Esophageal strictures are estimated to occur in 7-23% of untreated patients with reflux disease. But 25% are urelated to gastroesophageal reflux. This includes strictures secondary to external beam radiation, esophageal sclerotherapy, caustic ingestions, surgical anastomosis, and rare dermatologic diseases (eg, epidermolysis bullosa dystrophica). Strictures may also result from external compression of the esophagus due to mediastinal fibrosis induced by tuberculosis or idiopathic fibrosing mediastinitis. These conditions result in long and narrow strictures that are difficult to dilate, and in which dilation may be associated with a higher rate of complications.

The best option for the treatment of benign esophageal stricture is dilatation. This procedure is usually performed at the same time when upper endoscopy is done. Perforation is a rare complication, generally associated with dilation

Esophageal perforation is a well-characterized and potentially life-threatening clinical situation. Several factors, including the difficulty of accessing the esophagus, the lack of a strong serosal layer, the unusual blood supply of the organ and the proximity of vital structures, all contribute to this condition's high morbidity and to a mortality rate of at least 20%. In addition, the diversity of clinical symptoms and signs combined with a lack of individual experience regarding this particular condition may impede rapid identification of this potentially hazardous situation. Accordingly, delayed diagnostic work-up may hinder timely and appropriate treatment with a negative effect on patient outcome.


Carmen RODRIGUEZ (PALMA DE MALLORCA, Spain), Esperanza RIUTORT, Leticia BREGANTE, Rosa ROBLES, Maria GRANDE, Karina VALDEZ, Claudina REVOL, German FERMIN, Julio OLSEN, Enara BELANDIA, Bernardino COMAS
08:30 - 17:40 #11065 - A Comprehensive evaluation: Management of Sepsis Contingent with the Sepsis Screening Guidelines (NCEC), conducted in Portiuncula University Hospital, Galway Ireland.
A Comprehensive evaluation: Management of Sepsis Contingent with the Sepsis Screening Guidelines (NCEC), conducted in Portiuncula University Hospital, Galway Ireland.

Sepsis is the leading cause of death globally, claiming more lives than lung cancer, breast cancer, bowel cancer and HIV/AIDS combined.  It is a dysregulated inflammatory response whereby normal sterile tissue, fluid, or body cavity is invaded by a pathogenic organism. This leads to Sequential Organ Failure, Septic Shock, Multiple Organ Dysfunction Syndrome and finally Death. Recognition of sepsis in the Emergency department is crucial, and with appropriate education and quick recognition, Emergency Physicians can hugely impact the prognosis of a patient presenting with sepsis.

The aim was to analyze the recognition process, sepsis pathways and protocols, the management and prognosis of septic patients based on the diagnostic criteria for sepsis by the National Clinical Effectiveness Committee (NCEC) guidelines in Ireland. This retrospective study was carried out between the period of July 2015 to November 2015 when the Sepsis screening forms were put into use and highlighted as a risk stratification system for sepsis in Portiuncula University Hospital.   79 patients satisfied the NCEC guideline and their charts were analyzed and data recorded. The main elements studied included: Recognition of sepsis in triage, Completion of sepsis6, class of antibiotics frequently prescribed, adherence to guidelines with regards to antibiotics prescription, document status of Emergency Doctors, time taken to see a septic patient, types of blood tests including blood cultures and imaging, sepsis prevalence in Portiuncula University Hospital, mortality rates and appropriate escalation.

The total number of patients studied were 79(n=79). 43 sepsis cases were recognized during triage recognition of sepsis (54.4% CI,43:79). Patient Appropriately triaged to priority 2 were 71 (89.87% CI, 71:74). The mean time that septic patients are seen records at 39.17minutes. Sepsis6 completion with patients presenting with sepsis (100% CI,78:78). 72 out of 79 Antibiotics prescribed were adhering to guidelines (91.13%, 72:79). The study reported a 100% escalated care in terms of referral to the appropriate departments (100%, 79:79). ICU admissions were 23 in total (29.11%, 23:79). There were no mortalities resulting from sepsis in the ED during the term of the study.

The study showed that quick recognition will lead to prompt resuscitation (sepsis6) ushered by proper escalation. This, in turn, improves the prognosis for our patients significantly, reducing the mortality rate of sepsis. However continuous education, highlighting guidelines and the continuum of sepsis must be done to improve recognition and management.


Marcus JEE POH HOCK (Galway, Ireland), Kiren GOVENDER, Laura BANDUT
08:30 - 17:40 #11389 - A different diagnosis in left lower quadrant pain: Epiploic Appendagitis. A Case report.
A different diagnosis in left lower quadrant pain: Epiploic Appendagitis. A Case report.

Background: Epiploic Appendagitis (EA) also known as epiploicae appendices are peritoneal sacs that are protruding from the serosa of the colon. Their size ranges from 0.5 to 5 cm and their numbers range from 50 to 100, with fat or blood vessels in them. They are frequently located at the rectosigmoid junction and shows complications such as torsion or spontaneous venous thrombosis in the primer forms.

Case: A 53 year old female patient presented to emergency department with fever, weakness, loss of appetite, cough and left lower quadrant pain emerging and increasing after coughing during several days. Her vital were noted as fever: 38.1 0C, Pulse rate: 96 pulses/min, Respiration: 18 /min, BP: 113/78 mmHg. The oropharynx was hyperemic and oedematous, and there was no pathological sound in the lungs during her physical examination. But there was rebound in the left lower quadrant and tenderness with palpation with radiating pain on the umbilicus. Laboratory tests showed CRP: 8.21 mg/L, WBC:10160 /UL, Amylase: 60 U/L, urine test: normal. Due to age, fever, and left lower quadrant pain of the patient, Contrast-enhanced abdomen CT was ordered for the exclusion of diverticulitis, but CT revealed a number of images which resemble epiploic appendagitis, 18x11 mm in size in descending colon sigmoid level and contamination in surrounding mesenteric tissue (Figure 1,2). The patient was admitted to the general surgery clinic. The patient followed with conservative treatment was discharged 3 days after the hospitalization.

Discussion:In patients with complicated EA, abdominal pain, abdominal mass, and fever can be seen clinically at various durations and localizations. According to localization, appendicitis, diverticulitis, pelvic inflammatory disease, urinary tract infection, urinary tract stones, ovarian cyst or rupture should be considered. Though ultrasonography may be usefull for diagnosis but contrast-enhanced abdominal CT can detect pathognomonic pericholonic, oval or rounded shaped structures which are more dense and pediculated than adjacent peritoneal structures. Up-to-date management of epiploic appendagitis is conservative treatment and early diagnosis can prevent unnecessary surgery.

Conclusion: EA should be kept in mind besides other reasons in patients admitting to emergency deparments with left lower quadrant pain and abdominal CT use should not be forgotten for early diagnosis of these patients.


Oğuz EROĞLU, Ebru EMEKSIZ, Ömer YESILYURT, Turgut DENIZ, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #11534 - A female of epidural abscess, misdiagnosed as hyperventilation at first visit.
A female of epidural abscess, misdiagnosed as hyperventilation at first visit.

Introduction: Epidural abscess is a rare but the infection of the central nervous system(CNS) will potentially cause disastrous complications. The initial manifestations of epidural abscess include many nonspecific signs and symptoms such as fever, chills and malaise. It's hard to come up with the diagnosis at the first visit if patient presents symptom without neurological deficits. However, with more understanding of this disease, prompt recognition and proper management we gave can prevent patients from potentially disastrous complications.

Case Report: This 46-year-old woman presented to our ED because of lower back pain for one week. It occurred progressively with four limbs numbness, chillness, dyspnea and dizziness. The diagnosis of hyperventilation was made by other hospital few days ago. On arrival, her consciousness was clear and vital signs were as following: respiration: more than 30 breaths/min, pulse:103 beats/min, blood pressure:103/66 mmHg, and temperature: 37.1C. Chest auscultation are unremarkable and four limbs showed full muscle power. According to patient's statement, she sprained her back while play bowling a week ago, there was no any symptom of upper respiratory infection. Blood tests reported WBC 19040/ul, Hb 10.1g/dl, PL 492000/ul, N.seg. 87.9%. VBG reported pH 7.456, PCO2 30.0 mmHg, HCO3 20.7 mmol/L, Na 139 mmol/L, K 2.6 mmol/L, GLU 161 mg/dl. Liver and renal function are within normal limits. Urine analysis found no pyuria. After potassium supplement and diphenhydramine was given, her symptom and sign improved dramatically and was then allowed to discharged. However, she came to our ER again 2 days later by the problem of acute urinary distention and then 1000ml urine was drained by foley catheterization. Besides, the neurologic symptom of decreased muscle power of lower limbs (4) was found. The lab data was indicated to infection as CRP: 6.45 mg/dl and ESR >140 mm/hr. MRI was arranged which revealed L5/S1 spondylodiscitis with L5/S1 paraspinal and anterior epidural abscesses. After consultation with neurosurgical physician, she was admitted with antibiotics of Vancomycin and Ceftazidime. Although infection was under control after four-day treatment, urine retention remained a predominant problem while admission.

Discussion: There is no actual epidural space in normal circumstance. If the space was opened by mass or blood, it would cause neurologic deficits. The key to diagnosis is to consider this rare condition then to perform a physical examination followed by appropriate images. Magnetic resonance imaging (MRI) usually provides more information than computed tomography


Shih PU (Chiayi, Taiwan), Cheng PO-LIANG
08:30 - 17:40 #11777 - A modified HEART-score improves evaluations in chest pain patients with an elevated Troponin T.
A modified HEART-score improves evaluations in chest pain patients with an elevated Troponin T.

Background: Chest pain is a common symptom at the emergency department (ED) which often leads to admission for further investigation. HEART score is a structured scoring system which facilitates risk stratification. With the introduction of high-sensitivity cardiac troponin (hs-cTn) assays sensitivity for MI have increased with a lower specificity. The predictive value of HEART-score in patients presenting with an initial elevated (hs-cTnT) is unknown. 

Aim: To study whether HEART-score and its components predict MI and MACE in chest pain patients presenting with an initial elevated hs-cTnT.

Methods: All patients with chief complaint of chest pain presenting to the emergency department (ED) of Karolinska University Hospital, Solna,and Huddinge from January 2014 to December 2015 who had an initial elevated hs-cTnT (>14 ng/L) were followed 30 days regarding MACE defined as myocardial infarction (MI) and/or death in a retrospective observational study. Information on risk factors, history, ECG were extracted from medical files and an ECG-database and HEART-score was calculated. The association between HEART-score components and MACE was studied. In order to improve discrimination for MACE a simpler scoring system was tested (HEA021T) in which R were omitted and age was given 2 points for 45-65 years and 1 point for over 65 years

Results: A total of 648 MACE occurred among 2741 included patients. The proportion of MACE was 16.7% in those with a low (1-3), 23% in those with medium (4-6) and 42.9% in those with a high (7-10) HEART-score (p<0.001). A strong association was observed between MACE and the factors H (history) (p<0.001), E (ECG) (p<0.001) and T (Troponin) (p<0.001) whereas R (risk factors) did not predict MACE (p<0.782). Patients aged 45-65 years had a higher risk (37.1%) than patients over 65 (20.4%) (p<0.001). MACE occurred in 7% with a low (1-2), 29.4% with a medium (3-5) and 66.7% in those with high (6-8) HEA021T-score (p<0.001)

Conclusions: In patients with chest pain and an initial elevated troponin T risk factors did not predict MACE and the risk was highest among patients aged 45 to 65 years. A simpler modified HEAT score improved the predictive value compared to HEART-score. We suggest that HEAT-score should be used in patients with an initial elevated hs-cTnT. 


Jakob WESSMAN (Stockholm, Sweden), Per SVENSSON
08:30 - 17:40 #11014 - A new point-of-care device to measure erythrocyte aggregation in emergency setting: LAREHK 3-1.
A new point-of-care device to measure erythrocyte aggregation in emergency setting: LAREHK 3-1.

Background: Erythrocyte aggregation (EA) is a reversible phenomenon which is accelerated in many disease conditions with inflammatory response.  Current EA measurement techniques are too complex to be used in clinical setting.

Purpose: Clinical evaluation of the feasibility and usefulness of a point-of-care (POC) EA measurements in an emergency department (ED).

Method: We use a new POC device invented by one of us (OC) to optically measure EA kinetics (EAK) in 30s through a standard blood collection tube (EDTA). The study was conducted in Lariboisière Hospital’s ED during 11 days between January and June 2016. EAK was measured in consecutive, orally informed, patients who required a blood exam. Basic patient information, time of arrival, arrival modality, vital signs, pain scale, emergency triage level (1-5), patient complain and symptoms, ED diagnosis, ED length of stay, and discharge modality were collected. Each patient was contacted after 7 days to check her/his vital status, final diagnosis and new hospital admission. On-site biological values and hospital reports were reviewed to validate final diagnoses.

Results:  274 patients were included. 793 EAK measurements were performed. A mathematical model can be fitted to each EAK with a square regression coefficient > 0.99. Clinical and biological inflammation was assessed for each patient by two of us (OC, GA). Predicting powers of C-Reactive protein and of 3 halftimes derived from the EAK were compared. All 3 AEAK’s area under the Receiver Operating Characteristic (AUC) curves were larger than CRP’s (0.81). The best halftime (AUC = 0,86) was selected for further analyses. More specifically, patients with renal colitis (n=12), non-angina chest pain (n=16), headache or migraine (n=11) had “normal” EAK halftime (mean (SD))[minimum-maximum]: 2.34s(.44)[1.72-3.47], 2.1s(.49)[1.75-2.39] and 2.19s(.37)[1.53-2.66]. Patients with proven infection (n=23) or solid tissue cancer (n=8) had accelerated EAK: 1.65s(.22)[1.33-1.92] and 1.64s(.21)[1.35-2.15]. Patients with heart failure (without myocardial infarction) (n=14) had “normal” EAK: 2.08s(.49)[1.40-3.47]. In each diagnostic category there are a few outliers. The main reasons for these outliers were comorbidities (e.g. one patient had both renal colic and peripheral arterial disease (1.70s)). A 4-month pregnant woman with pneumopathy had “normal” EAK (2.11s).

Conclusion: Erythrocyte aggregation can be measured at the POC in EDs with results available in 30 seconds. This measure is highly specific of EAK. EAK is a powerful marker of inflammation and the first biological value available for medical decision. EAK can differentiate between patients with purely painful conditions such as renal colic, non-angina chest pain or headache and patients with underlying infection or inflammation. EAK profile in pregnant women should be investigated specifically.


Ghanima AL DANDACHI (Paris), Patrick PLAISANCE, Nahima GUEBLAOUI, Eric VICAUT, Olivier CHARANSONNEY
08:30 - 17:40 #11355 - A novel use of Point of Care Ultrasound in the early diagnosis of Neck of Femur Fractures in the Emergency Department.
A novel use of Point of Care Ultrasound in the early diagnosis of Neck of Femur Fractures in the Emergency Department.

Introduction:

Neck of femur fractures place a tremendous burden on emergency services worldwide. Multiple studies have demonstrated significant morbidity and mortality associated with this type of fracture. An early diagnosis and treatment with surgery has shown improvement in both morbidity and mortality.  An effective analgesic regime is paramount in the treatment of patients with neck of femur fractures. Fascia Iliaca Blocks (FIB) have shown to be effective in reducing pain as well as morbidity and mortality in hip fractures. Significant delays in obtaining X-rays would result in delays in adequate pain relief through FIB and definitive treatment. A novel use of Point of Care Ultrasound (PoCUS) however, could mean a diagnosis of a neck of femur fracture is reached within 2 minutes in Triage, with an immediate Fascia Iliaca Block performed afterwards. We have conducted a pilot study to test the validity of diagnosing neck of femur fracture with PoCUS in the ED. To our knowledge, no such use has been investigated before.

Methods: A prospective diagnostic pilot study was conducted, comparing PoCUS to x-rays of the pelvis/hip as a reference test in diagnosing hip fractures in the local Emergency Department from December 2016 to February 2017. All patients with a suspected hip fracture were included in this study. Objectively agitated and uncooperative patients were excluded. The lead investigator solely performed the hip ultrasound and confirmed ultrasound diagnoses, before x-rays were taken.  X-rays were subsequently reported by the Radiology Department without prior knowledge of the ultrasound diagnosis and compared. A Sonosite X-Porte Ultrasound machine was used. The exam was conducted with a C35XP 8-3 MHz probe, using the MSK setting.  The patient is in a supine position.  The ultrasound probe is placed longitudinally, probe marker cranially, on the lateral aspect of mid thigh.  The femoral cortex is visualised and assessed. The probe is then moved cranially, following the femoral cortex until the level of the greater trochanter is reached.  The probe is moved anteriorly to the groin, in line with the femoral neck, probe marker facing the umbilicus, visualising the acetabulum, femoral head and neck and joint capsule. The femoral neck is then followed down to the intertrochanteric region. Any cortical disruption is carefully assessed.

Results: A total of 46 patients were included in the study. 35 patients were female and 9 were male. The average age was 81. Sensitivity of Hip Fracture Ultrasound in our study was demonstrated to be 100% and specificity was 87.5%. Negative predictive value was 1. Positive predictive value was 0.94. Positive likelihood ratio was 8 and negative likelihood ratio was 0.

Conclusions: This pilot study demonstrated promising potential of PoCUS in diagnosing hip fractures. However, as this study covered a small sample size and one Emergency Physician, further studies are necessary to validate its use.


Yasir SHAUKAT (Reigate, United Kingdom), Csaba SZEKERES, Kamal VEERAMUTHU, Julian WEBB
08:30 - 17:40 #11072 - A prospective study to determine possible confounding factors in the detection of intracranial haemorrhage with the Infrascanner®.
A prospective study to determine possible confounding factors in the detection of intracranial haemorrhage with the Infrascanner®.

A prospective study to determine possible confounding factors in the detection of intracranial haemorrhage with the Infrascanner®.

M. De Leeuw, D. Mesotten, S. Van Boxstael, S. Van Poucke, W. Boer, M. Van Der Laenen, J. Van Zundert, R. Heylen, P. Vanelderen

Ziekenhuis Oost-Limburg, Genk, Belgium

 

Background: Prehospital detection of intracranial haemorrhage is important in order to triage patients to hospitals with a neurosurgery service. The Infrascanner® is a portable device designed to detect intracranial haemorrhage in battlefield traumas using near infrared spectroscopy. However, little is known about the accuracy of the Infrascanner®  in a low prevalence setting such as non-battlefield head trauma and little is known about other intracranial conditions that could influence the measurements of the Infrascanner®. We aimed to investigate the accuracy of the Infrascanner® in non-battle field traumas. Furthermore, we hypothezed that ischemic stroke, brain tumours, cerebral aneurysms and recent brain surgery could influence the accuracy of the Infrascanner®.

 

Materials and methods: In this prospective study we used the Infrascanner® in adult patients with non-battle field head trauma, ischemic stroke, recent brain surgery, brain tumours and cerebral aneurysms. A bilateral measurement with near infrared spectroscopy was performed using the Infrascanner® on the frontal, temporal, parietal and occipital region of the head. Clinical examination and an (angio-)CT scan of the brain was used to diagnose intracranial haemorrhage, ischemic stroke, brain tumour and cerebral aneurysm.

 

Results: We included 75 patients over a 4 month period (48% women, mean+SD age 61 + 19.3 years). In the majority of patients, the Infrascanner® was used after non-battle field head trauma (58.7%) followed by patients with a brain tumour (17.3%), ischemic stroke (14.7%), recent brain surgery (5.3%) and a cerebral aneurysm (4.0%). The percentage of false positive results was 65.9%, 76.9%, 100%, 75% and 66.7% in patients with non-battle field head trauma, brain tumour, ischemic stroke, recent brain surgery and cerebral aneurysm, respectively. The percentage of false negative results was 4.55% in patients with non-battle field head trauma and 0% in the other patients groups. In total 9 patients had an intracranial haemorrhage of which 7 were detected by the Infrascanner®. The overall positive predictive value was 0.11, the negative predictive value was 0.85, sensitivity was 0.78 and specificity was 0.17.

 

Discussion:  This study showed a high number of false positive results in patients with non-battle field head trauma, ischemic stroke, recent brain surgery, brain tumours and cerebrals aneurysms. However, the number of false negative results was low. Therefore, the Infrascanner® could be used as a screening tool to exclude intracranial haemorrhage. 


Marie DE LEEUW (Genk, Belgium), Dieter MESOTTEN, Sam VAN BOXSTAEL, Sven VAN POUCKE, Willem BOER, Margot VAN DER LAENEN, Jan VAN ZUNDERT, Rene HEYLEN, Pascal VANELDEREN
08:30 - 17:40 #10681 - A protocol for management of closed mallet finger deformity.
A protocol for management of closed mallet finger deformity.

Mallet finger is a common tendinous injury of the body (9.3%)1, which can result in permanent deformity if not treated appropriately.  Literature supports conservative management of closed deformities2, however the method and length of splinting varies. We assessed current practice in our emergency department (ED), and investigated management of chronic mallet finger (persistent deformity after 6 weeks).

A survey was sent to 11 ED consultants. The questions assessed diagnosis, treatment options, referrals and rationale for follow-up assessments

Diagnosis was primarily made by clinical findings and X-ray (55%), all treated with a mallet splint, and the majority only referred to orthopaedics if there was an avulsion greater than a third  (90%) of the distal interphalangeal joint. All clinicians arranged follow-up appointments, the primary at two weeks (75%) to assess skin integrity, and a secondary at 4 (9%) or 6 (81%) weeks to assess function and offer advice, with only one clinician having a solo follow up at 6 weeks. If a persistent deformity was present at 6 week follow up, clinicians opted to refer to orthopaedics (27%), persist with a splint (27%) and review in 6 weeks, a combination of both (45%) or remove the splint (9%).

Current practice was on the whole similar for mallet finger deformities, and confirms that mallet finger can broadly be treated in the ED. Given the nature of injury healing times, it was proposed that different regimes should be used for tendinous vs bony injuries. Follow-up is crucial for optimal patient outcomes; we have constructed a protocol for closed mallet finger deformity management based on current evidence.

 

 


Robert HAFES (Glasgow, United Kingdom), Paul MCNAMARA, Dan ANDERTON, Monica WALLACE
08:30 - 17:40 #10669 - A protocol for prolonged mechanical chest compression and E-CPR in patients with refractory out-of-hospital cardiac arrest.
A protocol for prolonged mechanical chest compression and E-CPR in patients with refractory out-of-hospital cardiac arrest.

Introduction: Prolonged mechanical chest compression and extracorporeal life support (ECLS) in the setting of cardiopulmonary resuscitation (CPR) is increasingly employed in patients with refractory out-of-hospital cardiac arrest (OHCA). However, no common consensus on inclusion and exclusion criteria for prolonged resuscitation and extracorporeal CPR (E-CPR) in OHCA patients has been established.

Methods: In 2013, the helicopter emergency medical system (HEMS) in South Tyrol, a mainly mountain province in the north of Italy with an area of 7.400 km² and about 520.000 inhabitants (and high seasonal tourists peaks), was equipped with LUCAS 2. Data were prospectively collected and included information on mission characteristics and clinical information including no-flow and low-flow time as well as the initial cardiac rhythm in OHCA cases were LUCAS 2 was employed. Based on inclusion criteria (i.e., cardiac arrest with primary HEMS transport), the decision to applicate LUCAS 2 and the destination hospital was at the discretion of the emergency physician. In South Tyrol, no hospital has ECLS capacity.

Results: Over a period of three years, LUCAS 2 was applied in 8 out of 271 HEMS-assisted OHCA patients. All 8 patients were transported to the Regional Hospital of Bolzano with no E-CPR capability. Seven of these patients died, one patients had ROSC at hospital arrival. After a review of all the cases, the need for a dedicated protocol emerged. Here we provide a protocol with inclusion and exclusion criteria for prolonged mechanical chest compression and transport to an ECLS-centre out of the province, which is based on a literature review and an agreement of an international group of experts.

Conclusion: The introduction of mechanical chest compression devices in HEMS in a region without ECLS capacity should involve precise indication criteria and the cooperation with an ECLS centre.


Simon RAUCH, Giacomo STRAPAZZON, Dr Monika BRODMANN MAEDER (Bern, Switzerland), Ernst FOP, Peter MAIR, Alessandro FORTI, Urs PIETSCH, Hermann BRUGGER
08:30 - 17:40 #10991 - A Rare Case of Adrenocortical carcinoma in a young adult.
A Rare Case of Adrenocortical carcinoma in a young adult.

S.Z. a 31 years old male came to the ED complaining face edema, weight gain, lower extremity swelling and haemoptysis. No history of neoplastic disease in family.He refered recent access to ED for the same symptoms and hypertension without fever and neutrophilia. The chest  x-ray had showed consolidation with homolateral pleural effusion and pulmonary congestion so he was treated for pneumoniae.At presentation his blood pressure was 150/100 mmHg. Physical examination decreased breath sound in the lower right lung was found. Laboratory studies showed high leukocyte count, high neutrophil, D-Dimer elevation, high LDH, hypokalaemia, metabolic alkalosis, hypercortisolism, hyperandrogenism, suppressed ACTH and normal metanephrines, consistent with adrenal Cushing’s Syndrome diagnosis.Ultrasound revealed right basal lung consolidation with omolateral effusion; an incidental mass was spotted at the upper side of left kidney. The CT scan showed acute pulmonary embolism with pulmonary infarction. Abdomen’s scans described the solid adrenal mass measuring 11x8x6 cm,  with vascular enhancement. It was found to invade diaphragm, vena cava with a big neoplastic thrombus inside. At CT scan paraortic metastatic linfoadenopathy was also reported. The patient underwent surgery with a complete debulking. Biopsy was positive for adrenal carcinoma. In view of the III stage disease he’s in treatment with Mitotane, Cisplatin and Etoposide. Adrenocortical carcinomas are rare malignant tumors (approximately 1-2 per million population per year). Most of them produce enough hormones to present a clinical Cushing's syndrome and/or virilization. In other cases they can be nonfunctional and present as an abdominal mass or as an incidental finding. A careful history and physical examination can help to exclude signs and symptoms of others endocrinology disorder. Fasting blood glucose, serum potassium, cortisol, adrenocorticotropic hormone (ACTH), 24-hour urinary free cortisol, adrenal androgens, and serum estradiol in men and postmenopausal women are useful to formulate a diagnosis; Radiographic studies and Fine-needle aspiration biopsy help to confirm histotype and mass characteristics. It’s important to exclude pheochromocytoma by testing urinary metanephrines and catecholamines. The only potential resolutive therapy is complete resection of the tumor and lymphadenectomy. A surgical pretreatment with glucocorticoid it’s important to avoid postoperative adrenal failure. Other useful therapies are, neoadjuvant  chemotherapy with cisplatinum for mass growth suppression and adrenolytic drug, to  control hormonal excess. The most effective drug is Mitotane. Steroid should be necessary during this treatment. In adults is not proved the utility of chemotherapy with cisplatinum plus etoposide. In conclusion this is a rare and heterogenic disease so it’s difficult to do diagnosis. It’s important not undervalue symptoms in young patients.


Daria TOSATTI, Elena CARELLA, Sabrina LUPACCIOLU, Francesca MORI (MODENA, Italy), Chiara GOZZI, Chiara OGNIBENE, Maria Cristina ROSA, Brugioni LUCIO
08:30 - 17:40 #11659 - A rare case of simultaneous bilateral femoral neck fractures.
A rare case of simultaneous bilateral femoral neck fractures.

Background

Whilst fractures of the neck of femur are commonly occurring diagnoses in the Emergency Department (ED), they rarely occur bilaterally and simultaneously without a high-energy trauma.

A current literature search shows only 23 cases of such diagnoses sustained during a seizure whilst our case being only the second reported in a patient with Down syndrome.

 

Case

A 56-year-old male was brought to the ED following his first tonic-clonic seizure, which occurred whilst in bed and lasted approximately for 5 minutes. The patient is known with Down syndrome and is non-communicative.

He was found to be immobile since sustaining the seizure and significantly distressed presumably with pain. Radiological imaging revealed bilateral femoral neck fractures and he was referred to the Orthopaedic team for urgent fixation.

 

Discussion

This case highlights some of the key characteristics found in this subset of patients which pre-dispose them to bilateral, simultaneous femoral neck fractures such as nutritional state, bone health and pharmacology.

Whilst clinical signs and early radiographs led to an early diagnosis, there is often a long delay partly due to the barriers in communication and the general lack of suspicion for bilateral femoral injuries without a significant history of trauma.

 

Conclusion

This case should serve to remind clinicians to keep an open mind to the possibility of this rare occurrence, both in this group of patients and in those with similar pre-disposing comorbidities.


Craig SELL, Abdo SATTOUT (Liverpool, UK, United Kingdom)
08:30 - 17:40 #11710 - A Rare Cause of Acute Abdominal Pain: Splenic and renal Infarction.
A Rare Cause of Acute Abdominal Pain: Splenic and renal Infarction.

     Splenic infarction is a rare clinical condition. The most frequent cause is embolic occlusion due to thrombus from atrial fibrillation. However, it is often difficult to diagnose because of its non-specific symptoms. Splenic infarction alone is not an indication for surgery. However, nonoperative management warrants close follow-up, and surgery is indicated for persistent symptoms or in the presence of complications such as hemorrhage, rupture, abscess, or persistent pseudocyst.

     Similarly, acute renal infarction is a rare clinical entity that most commonly occurs as a result of a thromboembolic  event in patients with predisposing risk factors. Its non-specific presentation can lead to delayed or missed diagnosis. However, modern imaging technology has allowed for the diagnosis of renal infarction to be made earlier in its clinical course. Due to its rare nature, treatment guidelines do not exist.

    68-year-old man admitted to emergency medicine department with complaint of abdominal pain and vomitting. He had a medical history of coronary artery disease but he did not use any medication including warfarin.

The pain was intensive On the abdominal examination, there was no rebound or tenderness. Abdominal X-ray revealed normal. On the ECG, he had atrial fibrillation.  The patient had the heart rate of 100 beam/minute, fewer 36.7 °C, arterial blood pressure 110/70 mmHg..The patient’s white blood cell (WBC) count is 10,000/uL, hemoglobin is 11.6 g/dL. The serum creatinine level was 0,8 mg/dL while the D-dimer was elevated to 0.99 μg/mL and LDH to 300 U/L. Abdominal contrast-enhanced CT angiography demonstrated perfusion defects in the left kidney and spleen. Anticoagulation therapy was started.

Splenic and renal  infarction are  a rare cause of abdominal pain. This case highlights the importance of considering alternate etiologies of localized abdominal pain when other common pathologies have been excluded.


Sibel SENEM BAS (EDİRNE, Turkey), Mustafa SAYHAN, Ömer SALT, Kubra ARSLAN
08:30 - 17:40 #10876 - A rare cause of chest pain in the emergency department: transdiaphragmatic extension of hepatic hydatid cyst. A case report.
A rare cause of chest pain in the emergency department: transdiaphragmatic extension of hepatic hydatid cyst. A case report.

Hydatid disease is a parasitic infestation by a tapeworm of the genus Echinococcus. Echinococcosis can involve any organ, but the liver is the most common organ involved, followed by the lungs. We present the case of a of 25 years old woman, who presented in the emergency department complaining of chest pain, cough and fever. Chest radiograph showed homogeneous opacity occupying 2/3 of right lung and an abdominal ultrasound showed the liver cystic image. CT of the chest was done thereafter, which revealed the presence of large cysts both in the lung and liver. The patient was treated surgically by one stage surgery of right thoracotomy with phrenotomy with favourable outcome. This case shows an unusual cause of chest pain in a patient presented in the emergency department, where chest radiography corroborated with a routine ultrasound raised suspicion of hydatidosis.


Vasile GAVRILA, Alexandru Nicolae CARSTEA (Timisoara, Romania), Rodica Daniela GAVRILA, Gabriela FILIP
08:30 - 17:40 #11658 - A Rare Cause of Neonatal Humeral Fractures: Cesarean Delivery.
A Rare Cause of Neonatal Humeral Fractures: Cesarean Delivery.

Introduction

Turkey and Iran have the highest CS rates (47.5% and 47.9% respectively) in Asia based on WHO data. Fetal injuries due to cesarean delivery are less common, compared to the vaginal delivery. In particular, in case of shoulder dystocia, breech presentation, first-feet position, twin pregnancy, and fetal macrosomia, the risk of fetal injury increases. Humeral fractures are the second leading long-bone fractures of the neonatal period.

Herein, we report a case who was delivered via emergency CS and referred to our emergency department (ED) with limited mobility in the right arm.

Case Report

A term female newborn, weighing 3.850g, was born from a 28-year-old mother via emergency CS due to the first-feet position had no history of hypoxia. On the sixth hour of her life, limited mobility in her right arm and lack of Moro reflex on the right side was noticed, and she was referred to our ED. Upon admission, her body temperature was 36.5oC, cardiac apex beat was 124/min, respiratory rate was 36/min, and blood pressure was 70/36 mmHg. Hypotonia and crepitation were detected in the right arm without Moro reflex. The remaining systems examination was unremarkable and her peripheral pulses were palpable. The right humeral shaft fracture was detected in the plain radiographs of the right arm in the ED. No neurovascular injury was found by doppler ultrasonography. Loss of tone and strength in the right arm was suspected due to pain-related limited mobility. In the ED, the right arm was cast, long arm splint was placed on the right upper extremity by orthopedic surgeon, and the patient was discharged with a scheduled follow-up visit three weeks later. At three weeks, the patient had no motor and sensory deficits. At the final visit at six weeks, the fracture line completely healed without any limited mobility.

Conclusion

Although cesarean delivery reduces the rate of trauma-related morbidity in neonates, it does not fully eliminate it. First full examination of all neonates especially in the operating room is the most critical step to diagnose delivery associated trauma/malformations. It should be kept in mind that mode of delivery, fetal malpresentation, and birth trauma in multiple pregnancies increase the risk. The present case highlights that humeral fractures may occur due to the maneuvers performed during CS. Suspicion, early diagnosis and treatment are critical steps to reduce possible neurovascular complications.


Caner TURAN (ISTANBUL, Turkey), Gulsum KESKIN, Ali YURTSEVEN, Huseyin GUNAY, Buket SACKIRAN, Eylem Ulas SAZ
08:30 - 17:40 #11130 - A rare presentation of hydatid cyst: biliary tract obstruction.
A rare presentation of hydatid cyst: biliary tract obstruction.

Introduction: Hydatid cyst disease is a parasitic infection caused by Echinococcus granulosus and a common health problem in our country. Hydatid cysts are more common in females and cysts can be identified in any region of the body but they are mostly identified in the liver. Patients are usually asymptomatic for years and cysts are diagnosed incidentally. Rarely, hydatid cysts localized in the liver cause biliary tract obstruction. Then, abdominal pain and jaundice become the leading symptoms of patients admitted to emergency department. Here, we want to present a female patient with huge liver hydatid cyst and biliary tract obstruction.

Case report: A 63-year-old female patient had presented to our emergency department with nausea, vomiting and abdominal pain occurred after each meal and ongoing for three days. She had no known prior disease in her past medical history. Her arterial blood pressure was 150/90 mmHg, pulse rate was 88/min, temperature was 36.6°C and oxygen saturation was 95% on admission. In her abdominal examination, the finding of epigastric tenderness was detected but there was no defense or rebound evidence.  In her laboratory tests, WBC count was 8,890/uL, hemoglobin was 14.1 g/dL, SGOT was 254 U/L, SGPT was 306 U/L, GGT was 284 U/L, ALP was 79 U/L, total bilirubin was 9.34 mg/dL, direct bilirubin was 4.89 mg/dL and C-reactive protein was 26.6 mg/L. We performed abdominal ultrasonography and intravenous contrast-enhanced abdominal computed tomography and the imaging tests revealed that there was a solid lesion compatible with type 5 hydatid cyst with a diameter of 7 cm in the left lobe of liver. Intrahepatic bile ducts are enlarged due to lesion compression in the left side of liver and there were multiple gallstones less than few millimeters in diameter. The patient was consulted with general surgeon and she was transferred to general surgery department for her definite treatment.   

Conclusion: Biliary tract obstruction due to hydatid cyst compression is a rare diagnosis in the management of abdominal pain and jaundice in the emergency department. Also, any anaphylactic reactions can be faced secondary to cyst rupture into the bile ducts. In our case, symptoms were only due to cyst compression and the huge hydatid cyst was diagnosed before rupture.


Zerrin Defne DUNDAR (Konya, Turkey), Merve GUVEN, Mahmut DEMIRTAS, Mehmet GUL
08:30 - 17:40 #11889 - A Review of Fitness Requirements for Disaster Medical Assistance Teams in the United States, what standard exists?
A Review of Fitness Requirements for Disaster Medical Assistance Teams in the United States, what standard exists?

Study/Objective

To review the publically availabled physical fitness requirements for disaster responders serving on disaster medical assistance teams (DMATs) in the United States.

Background

The United States has trained and credentialed teams of disaster responders which may be rapidly deployed to assist with search and rescue efforts and to provide essential medical care. This field work is physically and mentally demanding, placing team members themselves at risk. On prior deployments, many team members have sustained injury or illness requiring medical attention and, in some cases, extraction for off-site treatment.

Methods

Purpose: Describe the physical fitness requirements for DMAT responders in the United States

Format:Systematic review of public DMAT websites, December 2016. Search engine query for “[State/territory] DMAT” and “[State/territory] disaster medical assistance team,” review of first 3 pages of results

Population: All officially sanctioned DMAT teams in the United States with publically available websites

 Results

Of the 57 DMATs identified, 31 had publically available websites. Of these, 6 publish fitness requirements and 1 team has a self-administered fitness assessment.

Overview of requirements

DMAT 1: affidavit

DMAT 2: provides “Fitness Guide” with overview of basic health and nutrition concepts

DMAT 3: list of required functional capabilities

DMAT 4: list of required functional capabilities by team position

DMAT 5: self-administered fitness test and affidavit

DMAT 6: Health and Safety Assessment Plan, Human and Environmental Risk Assessment (HSAP, HERA)

Limitations 

Data set limited by public availability of DMAT websites

Cross sectional descriptive analysis

 

Recommendations

Standardization of physical fitness requirements across DMAT units and roles

Development of appropriate fitness testing protocol

Remediation protocols for responders in violation of requirements

It appears that no minimum physical fitness standard currently exists for federal disaster responders in the United States. Individuals may deploy with unknown physical liabilities, placing themselves and team members at risk of illness, injury, or mission failure. Given the hazardous nature of deployment to disaster zones which are, by their very nature, resource limited and may be physically remote from care, efforts should be made to develop and standardize minimum fitness standards for responders. By mitigating the risk of illness or injury to disaster responders, the likelihood of mission success and provider wellness can be increased.


Doug ROMNEY (Boston, USA), Reem ALFALASI, Brad NEWBURY, Ritu SARIN, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11353 - A review of patients presenting with ectopic pregnancy and their management pathway in a tertiary general hospital.
A review of patients presenting with ectopic pregnancy and their management pathway in a tertiary general hospital.

Background

Ectopic pregnancy is the leading cause of first trimester maternal death which often presents as a life-threatening emergency requiring prompt diagnosis and management. Ectopic pregnancy occurs in 2% of all pregnancies. The rate of ectopic pregnancy in Ireland was 14.8 per 1,000 maternities in 2012.

According to CMACE 2011 over 50% of cases of ectopic pregnancy presenting to the Emergency Department are missed on initial presentation.

The purpose of this study was to review all patients who presented with an ectopic pregnancy to a general hospital over an eight-year period and the management pathway of these patients.

 

Methods

Patients were identified through a hospital database. A retrospective chart review was performed on all cases and data was collected on a standard performa.

 

Results

Thirty-three women were diagnosed with an ectopic pregnancy during the study period. The average age was 33.1years (range: 27-45yrs). Notably, n=23 (67%) of cases were diagnosed on first presentation with n=10 (30.3%) being referred for further evaluation by a primary care provider. The numeric pain rating score recorded at triage varied from one to nine and positively correlated with the assigned triage category. In almost all cases n=32 (96.9%) vaginal bleeding was present and this was associated with abdominal pain in n=14 (42.2%) cases. The time from triage to review by the Emergency Department Doctor ranged from 0min to 495min with a mean of 124min. Two cases were not included as they were referred directly to Gynaecology-on-call from triage. The time interval to subsequent Gynaecology review ranged from 0min to 465min with a mean of 126min. All cases were managed surgically, with salpingectomy in n=32 (96.9%). There was one case that met acute maternal morbidity criteria, requiring over five units of red cell concentrate and Intensive Care Unit admission. Histology confirmed ectopic pregnancy in n=33 (100%) of cases.

A follow up gynaecology appointment occurred in n=24 (72.7%) cases, with n=8 (24.2%) cases not attending and one death due to multiorgan failure secondary to cardiac arrest.

 

Discussion

Our review hightlights that there is scope for improvement in the time interval following presentation to the Emergency Department to the time of review by an Emergency Department Doctor and referral to the Gynaecological team in this high risk patient cohort. A prompt diagnosis can help facilitate effective management of these patients and reduce morbidity.

 

 



Laurentina SCHALER (dublin, Ireland), Rupak SARKAR, Eimear MC SHARRY, Cliona MURPHY
08:30 - 17:40 #11011 - A Self-Assessment Survey of Healthcare Professionals at Alkhor Hospital in Qatar regarding Perceived Competencies in Disaster Management.
A Self-Assessment Survey of Healthcare Professionals at Alkhor Hospital in Qatar regarding Perceived Competencies in Disaster Management.

Back ground:A key concept of disaster management and planning is “emergency preparedness”. Development of education and training based on evidence based practice with due importance to regional, cultural and ethical issues is important. Health care workers have different training and exposure in disaster medicine.To prepare health professionals to respond appropriately to challenges and to work with experts in other fields, various organizations have developed competencies in disaster management.

AIM

A survey of health care professionals at Alkhor Hospital in Qatar was conducted to determine their perceived level of proficiency with competencies in disaster management.

Materials and Methods: This study was conducted in Alkhor Hospital during 1 Aug 2016 to 31 st December 2016. Health care professionals working across clinics, Inpatient units and critical araes were included. A survey questionnaire was distributed among the participants .The questions reflected the subject categories covered by the Disaster Medicine Certification Examination.Enrollment was purely on voluntary basis. The questionnaire was validated before the survey.Approval was taken from the ethical committee of the Medical Research Department of the institution. Strict confidentiality was maintained though out the survey .

Results:305 subjects were enrolled in the survey,of which 5 were excluded due to incomplete data. . Majority of them were nurses (n=152).Most of the participants had an experience of more than 8 yrs. 249 ( 83%) of participants had formal training in disaster management among which 51.4% completed online training .details shown in Figure-1.Regarding participation in disaster drills ,203 (67%) participants gave a positive response (Figure 2). On need for mandatory education in disaster management 87.33% (n=262), responded in the affirmative. Regarding competency in disaster management in general majority of the participant gave a score of average and good. While they scored poor regarding psychological issues in disaster

DISCUSSION

We found 78.67 % of the participants did not have any exposure to real disaster during their employment period.Our study validates the past survey done by  slepski et al who reported 85% of the participant to have prior training. Effective prior training ensures the safety and health of the health professional and other responders during a disaster. With the increase in web based training and easy availability of resources, a small study showed a trend in favor of web based interventions. However the trend was not statistically significant

CONCLUSION

Majority of the participant perceived that  they are competent in managing disaster in general. Majority of the participants have undergone formal training in disaster management. Regular drills and practice session are required to maintain the skills of the staff .In managing Psychological issues related to disaster, majority of the participants scored poor or average


Nishan PURAYIL (Qatar, Qatar), Carl SCHULTZ, Vamanjore Aboobaker NAUSHAD, Firjeeth PARAMABA, Naseem AMBRA, Sajid CHALIHADAN, Osama HASHIM
08:30 - 17:40 #11938 - A simplified criterion of successful radiofrequency ablation of the cavo-tricuspid isthmus.
A simplified criterion of successful radiofrequency ablation of the cavo-tricuspid isthmus.

Background: Radiofrequency ablation (RFA) of the cavo-tricuspid isthmus (CTI) is one of the most frequently performed procedures in electrophysiology. Cavo-tricuspid isthmus (CTI) ablation is the treatment of choice in preventing recurrences of typical atrial flutter (AFl). Bidirectional isthmus block is a criterion of successful ablation and is associated with the presence of different activation times on each side of the ablation line. Objective: The aim of this study was to determine a novel parameter clarify to improve a success rate in ablation of the CTI. Population and methods: We studied 35 patients with typical atrial flutter (60% male, mean age 48.5 +/- 10 years) who underwent successful ablation during tachycardia. The heart rhythm was sinus in 11% of patients and atrial flutter in 83% before the procedure. Electrophysiology mapping was used to confirm diagnosis of isthmus dependent atrial flutter, electro-anatomic position guide the ablation line creation and assess its efficacy. Before and after CTI ablation, activation times were measured on the low lateral right atrium under pacing from the proximal coronary sinus ostium (with a 600 ms cycle), on the proximal sinus coronary ostium under pacing from the low lateral right atrium. Results: Mean activation time between proximal sinus coronary ostium and atrial bipolar electrogram (SC-RA ) recorded from coronary sinus to low-lateral right atrium in sinus rhythm or in atrial flutter before the creation of the CTI block ablation were 103,7 ± 30,6 ms and. After the creation of the CTI block ablation, Mean activation times were 148,15±24,6 ms at low-lateral right atrium (LLRA) underpacing proximal sinus coronary ostium (PSCO) (PSCO -> LLRA) (P<0,001; r=0,54) and 143, 89±  30,36 ms at proximal sinus coronary ostium under pacing low-lateral right atrium to (LLRA -> PSCO ) (P<0,001; r=0,62). The linear regression equation that best described this result was: LLRA -> PSCO = 0,581 * SC-RA + 83,540; PSCO -> LLRA = 0,437 * SC-RA + 102,863. Conclusion: After atrial flutter ablation, the activation time between proximal sinus coronary ostium and atrial bipolar electrogram recorded at the low-lateral right atrium during atrial flutter or in the sinus rhythm of more than half this time before ablation plus 100 ms was associated with isthmus conduction block. This time criteria is very simplified criteria, make it easy to use in the routine ablation compared to others algorithm. This should however be confirmed before the end of the procedure through demonstration of bidirectional isthmus block.


Zied GUERMAZI (Trévenans), Sonia MARRAKCHI, Ikram KAMMOUN, Sami KASBEOUI, Skander MZEH, Marouene BOUKHRIS, Bechir ZOUARI, Ali MRABET, Selem KACHBOURA
08:30 - 17:40 #11478 - A Surprising Diagnosis of a Common Abdominal Pain presentation: A Case Report.
A Surprising Diagnosis of a Common Abdominal Pain presentation: A Case Report.

50-year-old gentleman previously healthy, who presents to Emergency Department (ED) with left hypochondriac colicky non-radiating pain, aggravated by heavy meal for five days and associated with severe diaphoresis and nausea. the patient became afraid to eat because of pain. No history of loss weight, change in bowel habit’s, blood in the stool. The patient denies recent travel, recent surgeries or history of the clot. No family history of clotting disorder or malignancy. The patient does not take any medications, no reported cigarette, alcohol, or drug use.  

He sought for medical advice twice and treated first time as a case of gastritis, and on second visit basic blood work including CBC, U&E, Lactate, LFTs was within normal range and ultrasound showed no abnormalities and discharged on Paracetamol and antacids.

The patient did not improve in spite of compliance with the prescribed medications and presented to our ED with the same complaint. On examination, the patient was stable vitally, with soft non-tender abdomen and normal bowel sounds. He underwent comprehensive study including CT abdomen with contrast which showed thrombosis of Superior Mesenteric Vein and its branches. The thrombus is seen extending, through Portal vein-occluding its lumen, to involve the splenic vein and right portal vein as well. After deemed surgically incorrigible, enoxaparin had been commenced, and the patient admitted to the medical ward.

During his hospital stay, the patient had no complaints, and his physical exam was normal.Gastroenterology consultation was made to arrange for Oesophago – gastro- Duodenoscopy, looking for malignancy which revealed erosive gastritis with significant modularity, Campylobacter-like organism test was negative, tumour markers (CA 125- CA19-9 CEA) were normal, homocysteine 13.9 (high), B12=111(low), work up for thrombophilia was normal.

 

Outcome and follow-up:

Patient discharged from the hospital with a diagnosis of Portal, superior mesenteric and splenic vein thrombosis secondary to hyperhomocysteinemia, B12 deficiency, and no other thrombophilic state. With a plan to start rivaroxaban 20 mg oral once daily, frequent follow-up at the medicine clinic.  

After six-month repeated CT abdomen revealed recanalization of the portal vein and splenic vein with partial recanalization of the superior mesenteric vein.

To our knowledge, portomesenteric thrombosis is a very rare complication to hyperhomocysteinemia, B12 deficiency as the patient had no other risk factors. For an unusual acute abdomen, not responsive to analgesics; suspicion of a portomesenteric thrombosis should be considered and investigated for.


Dr Ziad ALHARIRI (Doha- Qatar, Qatar), Sherif ALKAHKY, Mohamed QOTB, Mohamed MITWALLI
08:30 - 17:40 #11108 - A Temporal Disruption - A case report of temporal artery rupture from blunt trauma resulting in acute hemifacial swelling.
A Temporal Disruption - A case report of temporal artery rupture from blunt trauma resulting in acute hemifacial swelling.

Aneurysms of the facial vasculature are uncommon, with about 200 cases of superficial temporal artery (STA) aneurysms reported thus far, most of which are pseudoaneurysms presenting within weeks of trauma. We present a case of a gentleman who has a pre-existing vascular malformation of the forehead, who presented with acute onset gross hemifacial swelling due to a massive scalp and facial haematoma with mass effect on the ipsilateral orbital globe, after sustaining a closed blunt injury to his forehead when struck by an opening car door. He was diagnosed with transection and traumatic pseudoaneurysm of the STA via computed tomography scans and angiogram of the STA, for which he underwent extracranial angio-embolisation, with subsequent surgical exploration and evacuation of the haematoma and resection of the underlying vascular malformation. Due to its superficial course, the STA can be injured in blunt head trauma, and a rupture can present with acute hemifacial swelling. Early active intervention with endovascular or surgical means should be considered.


Dr Lim JIA HAO (Singapore, Singapore), Mong RUPENG
08:30 - 17:40 #11986 - A young adult patient presenting with involuntary contractions at neck.
A young adult patient presenting with involuntary contractions at neck.

Introduction: Dystonia is a neurological disorder characterized by involuntary, continuous or spasmodic, intense muscular contractions of both agonist and antagonist muscles simultaneously. Acute dystonic reaction manifests with contractions of especially the muscles in the face, neck and back, opisthotonus, torticollis, oculogyric crisis, dysarthria and trismus. Drugs are the most common etiological factors causing dystonia. Various drug groups such as antipsychotics, antiemetics, antihistaminics, decongestants and expectorants can cause dystonia. Even the therapeutic doses of these drugs have been shown to cause dystonia. Haloperidol, an antipsychotic drug, is one of the most commonly encountered cause of this condition. Various conditions including encephalitis, hypocalcemia, seizure, convulsion, insect bite and tetanus may be confused with dystonia. The condition requires prompt diagnosis and treatment.

The Case: Eighteen year-old male patient presented to the emergency department with complaint of involuntary contraction at his neck. He had pain at right side of his neck due the involuntary contractions. He also complained of involuntary gaze toward up and left in both eyes. His medical past history did not include any systemic disease, or chronic drug use or substance abuse. His vital signs were within normal range. In his physical examination, he appeared agitated, he was conscious, oriented, and was cooperating. He had involuntary repetitive contractions at his neck that lasted nearly a minute, tilting the head towards back and left side (Figure). Both eyes showed involuntary movements to up and left side. Other neurological and systemic examination findings were normal. His laboratory findings were normal except elevated creatine kinase levels (CK:653 U/L). In order to rule out central nervous system pathologies, a computed tomography scan was performed, and it was evaluated as normal. Since the patient's clinical findings suggested dystonia, a further detailed history was taken. Drug use was asked insistently, and then the patient told that he was working as a health worker in an intensive care unit of a hospital, and that his symptoms started three hours ago after he took 2mg haloperidol at his own will without consulting anyone, in order to sleep comfortably. As he did not have any previous history, the patient was diagnosed with acute dystonia due to ingestion of haloperidol. Biperiden 5mg (Akineton® ampoule) was administered intramuscularly, and his complaints improved after half an hour. He got well during observation in the emergency department, and was discharged with recommendations.

Conclusion: Dystonia should certainly be considered in every patient presenting to emergency department with involuntary muscle contractions. Since drugs are a common cause of dystonia, a detailed history including drug use should be obtained. It should be kept in mind that patients can sometimes withhold some details that they think are not relevant.


Atif BAYRAMOGLU (Erzurum, Turkey), Ilker AKBAS, Abdullah Osman KOCAK, Oktay OZPOLAT, Zeynep CAKIR
08:30 - 17:40 #11640 - Abdominal distension revealing megadolichocolon.
Abdominal distension revealing megadolichocolon.

Introduction :

Diarrhea, abdominal pain and distension are frequent findings in emergency department. They can be banal complaints or may lead to the diagnosis of life threatening situations. A clear history taking and examination are the cornerstones of an accurate clinical decision making especially in the emergency department.

Case report :

We report a case of a 42-year-old woman with no medical history, except surgery 4 years prior for intestinal occlusion, wich was admitted to the emergency department with complaint of an important abdominal progressive distension over 2 months, frequent episodes of diarrhea within last 24 hours and few episodes of vomiting. On examination: patient was counscious, afebrile, with stable blood pressure, regular tachycardia 120 bpm, pulse oximetry on air = 92% and respiratory rate = 22 cycles per minute. The abdomen was huge on inspection, asymmetric with bulging flanks, periombilical tympanism and decreased bowel sounds. On rectal exam, loose stools were noticed. Abdominal Computerized tomography showed sigmoid and left colon distension with dolichocolon and voluminous fecal impaction measuring 17 cm. Patient was urgently transferred to the surgical ward but evolution was rapidly fatal on first 24 h after admission.

Discussion and conclusion:

Dolichocolon is an abnormal long large intestine and is often incidental finding on X-rays. This situation is more frequent in elderly and may expose to  mechanical malrotation. while megacolon is an abnormal dilation of the colon and can be congenital or acquired idiopathic, infective, due to toxic or medication use. The association megadolichocolon is rare exposing to fecalomas impaction and mechanical complications.


Yasmine WALHA (Tunis, Tunisia), Hamed RYM, Feten AMIRA, Héla BEN TURKIA, Abir WAHABI, Abderrahim ACHOURI, Mohamed KILANI, Chokri HAMOUDA
08:30 - 17:40 #11821 - Abdominal Pain İs Not Just Abdomen.
Abdominal Pain İs Not Just Abdomen.

Introduction: Sudden onset of abdominal pain is one of the most common reasons of admitting to emergency department (ED) but pneumothorax presenting with abdominal pain is rare. In this case; it is aimed to point out that patients with abdominal pain admitted to ED mus t be carefully evaluated and pneumthorax should be considered. 

Case:Twenty-five year-old male ptient with no prior medical history admitted to our ED with severe left upper quadrant pain. There no major physical examination findings except left upper quadrant tenderness. Vital signs were blood pressure: 110/80mmHg Heart rate: 78 bpm sO2: 96%. Lanoratory fşindings were normal. For atypical abdominal pain chest and abdomen graphy performed. The absence of parenchyma in the left lung was determined. Pneumothorax was confirmed with thorax computed tomography. The patient admitted to hospital for chest tube insertion. 3 days after admission no complication observed and patient discharged from hospital.

Discussion: The incidence of primary spontaneous pneumothorax among men is approximately 15 cases per 100000 population per year. Smoking and changes in atmospheric pressure are the risk factors associated with rpimary spontaneous pneumothorax. In this case diaphragma irritation was thought to be the reason of the abdominal pain. most patients with pneumothorax present with acute pleuritic chest pain localized to the side of the pneumothorax. Dyspnea tachycardia, hypotension and hypoxia are also common symptoms of pneumothorax but abdominal pain isnot a common presentation. Clinicians must be careful about abdominal pain and chest x-ray must be perfomed for all patients with abdominal pain.


Erkman SANRI, Arda KOCATAŞ (istanbul, Turkey), Sinan KARACABEY
08:30 - 17:40 #11493 - Abdominal X-Rays in the Diagnosis of Acute Abdominal Pain.
Abdominal X-Rays in the Diagnosis of Acute Abdominal Pain.

INTRODUCTION  

Plain abdominal xrays are readily available, however diagnosis and management is not often changed by this investigation. This raises questions about the value of such an investigation. One recent study on the available evidence concluded that in current practice there was no place for routine abdominal radiography. There is evidence that many doctors would benefit from further training in developing skills for reviewing x-rays.

OBJECTIVE   

This is a retrospective study carried out at George Eliot Hospital, Nuneaton to see the efficacy of abdominal x-rays in the diagnosis of acute abdominal pain.

METHODS   

Medical Records of 200 patients who had an abdominal x-ray ordered for acute abdominal pain were reviewed. X-ray reports of the radiologist were recorded. Findings were correlated with the final definitive diagnosis.

RESULTS  

Only 27 out of 200 showed any abnormality. 173 x-rays were reported as normal. Distended loops of bowel were seen in 18, implying acute intestinal obstruction, although further investigations were required to confirm the diagnosis. Renal calculi were seen in 6 cases. Perforation was recognised in two cases and gall-stones were seen in one abdominal x-ray.

DISCUSSION  

It has been customary to do a x-ray of the abdomen routinely for acute abdominal pain. We did not think that x-ray made any contribution in making a diagnosis of acute abdominal pain. This study clearly demonstrates that abdominal x-rays can help in the diagnosis of acute intestinal obstruction but do not provide enough information to confirm the final diagnosis. The diagnosis of perforation requires a chest x-ray. Abdominal x-ray was of no value in the diagnosis of Haematemesis.

CONCLUSIONS

It is clear from our study that abdominal x-ray adds little diagnostic value to the patient who presents with acute abdominal pain. There are other diagnostic modalities that are more efficient and reliable in confirming a diagnosis relating to the acute abdomen. 


Mohammad ANSARI, Ahmad ISMAIL, Pankaj KUMAR (BIRMINGHAM, United Kingdom)
08:30 - 17:40 #11910 - About 8 cases of acute respiratory distress by infection with H1N1 virus.
About 8 cases of acute respiratory distress by infection with H1N1 virus.

Introduction:H1N1(hemagglutinin-H-neuroaminidase-N) influenza infection is associated with high morbidity and mortality because of associated complications and related factors.the aim of our study is to describe the clinical features,complications and different risk factors that affect the outcome in the patients with confirmed H1N1 influenza infection.

Material and methods:a prospective study was conducted in the emergency department of Charles Nicolle hospital in tunis,Tunisia over a period of 4 months going from junuary 2016 through April 2016,including patients aged over 14 years old with acute respiratory distress syndrome.we condidered only patients with confirmed H1N1 infection.

Results:among the 8 patients in the study,62.5% of the patients were male with mean age of 58.38+-18years. Dyspnea and high respiratory rate were observed in all patients,while fever was noted in 62.5% of the cases. On the basis of disease severity,all patients were in hypoxemia,25% in acedemia,62.5% with hyperlactatemia. Non invasive ventilation has been put on in 62.5% of cases,while mechanical ventilation has been required in 37.5%.The average of FINE score was 117.63+-51.75 and CURB65 score at 1.75+-1.035. None antiviral treatment wad administrated,though double antibiotherapy was conducted for all patients. Mean hospitalization period was 56.75+-48.72 hours. During the hospitalization,37.5% of patients required the use of vasoactive drugs. The mortality rate was of 37.5%.

Conclusion:the results of our study suggest that low oxygen saturation during admission,acidemia,hyperlactatemia,high FINE and CURB65 score and the appeal to mechanical ventilation,influence the mortality rate of patients with H1N1 infection.


Zammiti ALA, Zammiti ALA (Tunis, Tunisia), Khaoula RAMMEH, Azza YEDEAS, Bassem CHATBRI, Abderrahim ACHOURI
08:30 - 17:40 #11351 - ABOUT A STRANGE CASE.. NOTHING IS AS IT SEEMS.
ABOUT A STRANGE CASE.. NOTHING IS AS IT SEEMS.

ABOUT A STRANGE CASE ...NOTHING IS AS IT SEEMS ...

 ABSTRACT

What is often mistaken for pneumonia based on objective tests is actually the result of a restorative response of the Lung in a aggredente agent like a virus, toxic fumes or even a medication.

Some people are more susceptible than others to the development of this strange pneumonia-pneumonia, not specifically who is recovering from cancer or recruiters who takes certain medicines such as amiodarone and Statins for cholesterol control.
KEYWORDS

PERSISTENT COUGH-DYSPNEA-BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA

CASE REPORTS

Come to our observation a female subject of 59, a history of episodes of the Navy, home therapy with beta blocker (nebivolol). Denies allergic Diathesis for Aeroallergen or medications.

Log into PS for symptomatology characterized by flu-like framework, dry cough, shortness of breath and fever to worsening trends. The patient had practiced therapy with antibiotics and prescription of his home GP's without benefit of any.

Performing blood tests that show a mild leukocytosis (WBC 12800) not related to the severity of clinical presentation; therefore cash outs for exam emogasanalitico with evidence of mild hypoxemia (pO2 72), deficit being compensated.

On physical examination emitoraci symmetric in static, dynamic, ipetrasmesso, auscultano in FVT hypomobile ronchi, boos and hisses.

Practicing therapy with metilprednisoloneemisuccinato 40 mg betamethasone + salbutamol + ev and aerosol therapy ingredient ipatropium, to follow or2 low flow.

The improvement in symptoms (in spite of the persistence of an improved finding of broncostenosi), you send your patient at the Radiology unit to undergo chest radiography with evidence of "discreet accentuation of interstitial peribroncovasale plot in reticular nature more evident in the lower lung fields. Doesn't documenting pulmonary lesions grates with character of activity norpleural abnormalities ".

You perform detailed diagnostic study with Tc that CHEST documents "at the right lung lobe and localized also distributed to all subpleurica and iuxtascissurale, you document pulmonary parenchymal density gradient areas for multiple looks at" frosted glass ", some with pseudo-Nodular morphology. some Nodular-like area with similar characteristics also left pulmonary lobe densitometric is identifiable in the upper and lower. -Mainly localized in some parenchymal not bilaterally ) Pilomatricoma mantle of undetermined nature seat for small size likely expression of inflammatory involvement of small Airways. Diffuse bronchial wall thickening is detected, nonspecific changes expressions of type bronchitic and peribronchitico. Pleural and pericardial cavity-freepouring " 

So she was  recover at our Department of emergency medicine and takes appropriate oxygen therapy, nutritional support to compensate for the increased caloric requirements due to the work of breathing and proper dose cortisone therapy for symptoms and body weight.

DISCUSSION

The bronchiolitis obliterans (BOOP) is a chronic disorder secondary to a severe impairment of the lower Airways. There are many factors that can cause skin lesions which underlie the development of boop such as inhalation of toxic gases and fumes (especially NO2), the graft versus host disease following bone marrow or lung Allograft transplantation, Steven-Johnson, bronchiectasis; bronchiolitis is often prodromal expression of systemic disease, generally of the connective tissue (1).

The idiopathic forms generally affect females in adulthood but probably  the incidence is underestimated because it is often a diagnosis of chronic obstructive pulmonary disease (COPD).

From pathogenetic point of view the BOOP is characterized by partial or complete obliteration by the fibro-lumen scar of Terminal Bronchioles and respirators. The noxa determines an initial damage to the epithelium of the small Airways inducing proliferation of myofibroblasts present in the submucosa and the subsequent deposition of endobronchial granulation tissue with concentric fibrosis evolution towards and eventually obliteration of small Airways.

Lymphocytes and neutrophils play a key role in the initiation and maintenance of pathogenetic mechanism, as well as documented by their presents in BL (bronchoalveolar lavage).

In particular increased the activated lymphocytes (CD3 + HLADR +) and Lymphocytic subtype CD8 +

In this regard are interesting observations regarding BO from lung transplant which suggested a central role of T-mediated immune response against the collagen type V.

Diagnosis is formula through a CT scan and a bronchoscopy, thanks to the technique of broncolavaggio, an examination that allows the analysis of cells in the lung. Bronchoscopy, fortunately, is a non-invasive examination which is done in outpatient offices with a light sedation and lasting a few minutes.
Once you have established the existence of the disease, treatment is cortisone-based, which allows an immediate improvement of symptoms and continued for some months. The proportion of patients presenting relapse after stopping the cortisone is very low. In these cases, treatment is resumed, assiduously checking that cortisone will not produce well-known side effects, namely raising the levels of blood glucose, osteoporosis, weight gain. In some cases, it should also be excluded the presence of other diseases, such as rheumatological, whose BOOP might constitute only a signal

As far as diagnosis may include the need to practice a trans-bronchial biopsy (FBS) with a nodule or a lung biopsy needle under CT guidance trans-parietal, unique exams can provide histological confirmation, clinical radiological documentation particularly seriata in time and the lack of response to antibiotic therapy often allow the pulmonologist expert to treat the patient even in the absence of histologic confirmation, with a proper cortisone therapy for amounts and times. The drug predominantly used is prednisone, given generous dose and for sufficient to exclude recidivists (for months). The experience of the specialist can help you resolve often the clinical picture of COP/BOOP without necessarily having to resort to more risky investigations remember above, reducing the risk of recurrence in any case of the disease, however contemplated in a number of cases, although they adopt adequate cortisone therapy and limiting to a minimum the risk of unwanted side effects secondary to prolonged use of cortisone.

 BIBLIOGRAPHY

  1. "PATHOPHYSIOLOGY OF OBLITERATIVE BRONCHIOLITIS IN LUNG TRANSPLANTS"-M Reynaud-Gaubert. Rev Mal Respir 20 (2 Pt 1), 224-232. 4 2003.

  2. BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA: PATHOGENESIS, CLINCAL FEATURES, IMAGING AND THERAPY REVIEW – Al Ghanem Sara, Al Jahdali Hamdan and Khan Ali Nawaz

  3. “BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA AFTER THORACIC RADIOTHERAPY FOR BREAST CARCINOMA” – R. Cornelissen, S. Senan, Joachim GJV Aerts

  4. “BRONCHIOLITIS OBLITERANS SYNDROME (BOS), BRONCHIOLITIS OBLITERANS ORGANIZING PNEUMONIA (BOOP) AND OTHER LATE-ONSET NON INFECTIOUS PULMONARY COMPLICATIONS FOLLOWING ALLOGENEIC HEMATOPOIETICSTEM CELL TRANSPLANTATION”- S. Yoshihara, G. Yanik, S. Mineishi


Santa PELLICANO (REGGIO CALABRIA, Italy), Maria Rosa GIOFRE', Rocco CARIDI, Paolo COSTANTINO, Angelo IANNI
08:30 - 17:40 #11238 - Access to pre-hospital care: typology of accessibility constraints encountered by emergency mobile services and their role on delayed time to patient contact in a French urban area.
Access to pre-hospital care: typology of accessibility constraints encountered by emergency mobile services and their role on delayed time to patient contact in a French urban area.

Introduction:  In urban areas, accessibility constraints are frequent and appear responsible for extended emergency mobile services’ response times. Detailed analysis of terminal access until patient contact (ambulance parking, walking path) has been little undertaken. As a result, factors of accessibility constraints remain unknown.

We aimed to describe the components of accessibility constraints encountered by emergency mobile services, and to compare response times upon the presence of accessibility constraints in an urban area.

Method: Multicentre prospective cohort study involving adult patients receiving care of 5 emergency mobile services in a French urban area. Collected data were geographical and architectural criteria, types of accessibility constraints, parking and patient contact times. Comparison of response times upon the presence of accessibility constraints (t-test).

Results: 1021 patients included between July 1st and April 1st, 2016. Scene locations were mainly at the patient’s home (76%, n=774), which was located in a multi-story building in 54% (n=553). Accessibility constraints were encountered in 41% (n=422). When met during the parking of the ambulance (57%, n=239), 58% were due to physical obstacles (n=144) and 53% to imprecise address (n=128). When met during the walking path (69%, n=291), 67% were exterior (gates, doors, long distance)(n=194) and 52% interior (doors, codes, lift issue)(n=151). When present, time to patient contact was higher (3.3±1.99min vs. 1.8±1.12min, p<0.001).

Discussion: SMUR ADs were frequently seen in our study. They mainly appeared in groups of flats with more than three stories and principally affected journey elements made indoors and on foot. Where ADs occurred, journey times for SMUR teams were higher. SMUR response quality evaluation should take into account journey elements made on foot in order to establish strategies for improvement.


Elise BRAMI, Matthieu HEIDET (Créteil), Jean MARTY, Eric LECARPENTIER, Etienne AUDUREAU, Thierry DA CUNHA
08:30 - 17:40 #10898 - Achieving evidence in mountain emergency medicine with the help of registries.
Achieving evidence in mountain emergency medicine with the help of registries.

Performing randomized controlled trials in prehospital emergency medicine is challenging: A PubMed search with the expressions “RCT” and “prehospital emergency medicine” revealed 15 publications, of which seven were reviews.  The Cochrane reviews themselves found limited evidence for emergency endotracheal intubation (3 RCTs), prehospital cooling (7 RCTs) or an update on the effectiveness of the Valsalva maneuver (0 new RCTs) due to  lack of sufficient data. Some authors even warn that “… EMS is completely unsupported by scientific fact...”

International registries aim to challenge this lack of evidence by collecting information all over the world. A registry is a database of information about patients with specific types of diagnoses. It collects information that can be used for capturing, organizing, managing, and evaluating information for a population of patients (AHRQ 2014). Especially in rare diseases, where the know-how of the team that takes care of the patient can be vital, registries can help to obtain information about or even recommendations for good clinical practice. In the challenging setting of alpine prehospital emergency medicine, registries that do not only involve medical but also technical and environmental information can be a crucial source to develop important recommendations. The International Hypothermia Registry IHR, the International Alpine Trauma Registry IATR and the International Avalanche Registry IAVAR are three different registries with a focus on special situations in mountains.

The International Hypothermia Registry IHR (www.hypothermia-registry.org) is the first and only world wide database on human accidental hypothermia. This internet based registry was created by the hypothermia working group with the University Hospital of Geneva, Switzerland which hosts the data on its secure server. The IHR’s principle goal is to increase knowledge on accidental hypothermia by gathering sufficient relevant data through international networking, creating the largest data base on deep accidental hypothermia. The registry will enable comparison of treating and rewarming methods, study survival predictor factors and prevention of post rewarming complications. This will help select the most efficient ways to treat these patients and permit the establishment of evidence based diagnosis and treatment guidelines.

EURAC research in Bolzano / Italy established both the International Alpine Trauma Registry IATR and the International Avalanche Registry IAVAR. The IATR aims to collect and report information in a standard form on major alpine trauma. It includes patient pre-hospital, in-hospital and outcome information. The IAVAR aims to determine and compare the key characteristics of prehospital care and patterns of injury in avalanche accidents with persons involved. Its goal is to determine the impact of rescue strategies and treatment recommendations on patient outcomes.


Dr Monika BRODMANN MAEDER, Dr Monika BRODMANN MAEDER (Bern, Switzerland), Simon RAUCH, Giacomo STRAPAZZON, Hermann BRUGGER
08:30 - 17:40 #11160 - Acquisition of electrocardiograms by first aid teams and their transmission to Paris medical dispatch center - a prospective observational study.
Acquisition of electrocardiograms by first aid teams and their transmission to Paris medical dispatch center - a prospective observational study.

Background: The care of an acute heart disorder (rhythm disorder, conduction disturbance, or acute coronary syndrome) is based on a rapid diagnosis and access to a cardiac unit. For the emergency physician at the dispatch center, the diagnosis of heart disorders may sometimes be difficult, especially in the case of patients with a non-typical clinical presentation. In this situation, the transmission of an electrocardiogram (ECG) by first aid teams to the dispatch center may save the patient some time. The main purpose of this study was to evaluate the time between the first alert and the receiving of the ECG by the dispatch center.

 

Materials and methods: This prospective observational study was approved by an ethics committee. Inclusion criteria were: 1. absence of an evocative sign of a serious cardiac disorder during the initial call to the dispatch center; 2. decision by the dispatch center's physician to perform an ECG on site by the first aid team. First aid professionals were trained to record and transmit ECG to the dispatch center. We collected patient’s age and gender as well as the time between the first alert and the receiving of the ECG by the dispatch center. We show the median [interquartile range] or the rate (%) according to the quantitative or qualitative nature of the variable.

Results: The median of the time between the first alert and the receiving of the ECG by the dispatch center was 36 min [29–44]. Between the 10th of October 2016 and the 6th of November 2016, the dispatch center registered 36,725 calls with involvement of a first aid team. We recruited 950 patients. The median of the age was 53 years-old [39–70]; 486 patients (51%) were men.

 

Discussion: For patients with cardiac symptoms not evocative of a serious disorder, we believe that the time to obtain an ECG read by a physician would have been much longer if patients must have been brought to the emergency department prior to the aquisition of the ECG.

 

Conclusion: Electrocardiograms performed by first aid teams are a complementary tool available to the emergency physician at the dispatch center. Their place in the strategy of patient’s care deserves to be studied further.


Romain KEDZIEREWICZ (Brignoles), Benoit FRATTINI, Daniel JOST, Pascal DIEGELMANN, Emilie TAUVRON, Frédérique BRICHE, René BIHANNIC, Michel BIGAND, Jean-Pierre TOURTIER
08:30 - 17:40 #11642 - Acute aortic dissection: vital emergency.
Acute aortic dissection: vital emergency.

Background:

Acute aortic dissection (AAD) is a severe condition characterized by the sudden burst of blood inside the aorta wall [1]. The atypical forms mean that the emergency physician must be vigilant before any chest pain presenting to the emergency.

 

Case report:

We report the case of a 52-year-old man with no past medical history who presented to the emergency department for severe, thoraco-abdominal, syncopal pain, followed by deep asthenia, vomiting and  sweating.

Examination at admission found: BP = 280/120 mm Hg, pulse = 123 beats / min, FR = 20 cycles / min. BP was symmetrical at the two limbs and the peripheral pulse was present and symmetrical. The ECG showed sinus tachycardia with no repolarization or conduction disturbances with presence of atrial extrasystoles. The diagnosis of AAD was discussed in the emergency room in the absence of signs of ischemia on the ECG.

Exploration by aortic angiography showed a type B aortic dissection beginning downstream the left subclavian artery  to the right primitive iliac artery with dissection of the right renal artery emerging through the side channel which is compressive associated to a decreased right nephrogram with the superior mesenteric artery irrigated by the real channel which is in low flow. The cardiovascular surgeons concluded to a type B AAD and declined the surgical emergency. The patient received intravenous antihypertensive therapy (Nifidipine: 15mg / hr + isosorbide dinitrate 7mg / hr) until strict control of the blood pressure BP = 110/60 mm Hg. Evolution was marked by rapid aggravation with an instability of the haemodynamic state, an alteration of the state of consciousness with recourse to mechanical ventilation and the patient died at H24.

Discussion: ACD management differs depending on the type of dissection. However, in severe forms between the two types A and B, the worsening may be sudden and rapid, emphasizing the importance of appropriate cardiovascular surgery.


Ahmed SOUYEH (tunis, Tunisia), Hana HEDHLI, Sarra JOUINI, Imen MEKKI, Yasmine WALHA, Abderrahim ACHOURI, Hela BEN TURKIA, Chokri HAMOUDA
08:30 - 17:40 #11917 - Acute coronary syndromes in the emergency room: evaluation of the quality of care.
Acute coronary syndromes in the emergency room: evaluation of the quality of care.

Background: Coronary heart disease remains among the main causes of mortality, which leads us to strive on improving outcomes in patients with acute coronary syndromes (ACS). Like any other ischemic conditions, time is crucial, so we increasingly try to reduce delays and go as fast as possible to enhance results.

Methods: We studied the path of 50 patients without medical history of coronary heart disease, who came to the emergency department for symptoms which have been related, after investigations, to an acute coronary syndrome. We recorded all stages of care from the moment of registration until his discharge.

Results: The sample consisted of 14 female and 36 male patients. The male/female ratio was 2,57. 78% of patients arrived on their own. Only 6% have been transferred to us by medically-equipped ambulance. 94 % have reported a chest pain. 8% of patients had a cardiogenic shock. Only 14% arrived within the first 2 hours after the beginning of symptoms. 40% arrived within the 6 first hours. The median time to perform an electrocardiogram upon arrival was 17 minutes, with a maximum time limit of 285 minutes. 74% had one ultrasensitive troponin dosage at least. All patients received aspirin after arrival, with a median time of 74 minutes. All patients received heparin, the median time was 57 minutes. 83% received clopidogrel after arrival in the ER with a median time of 116 minutes. Only 8% of patients received clopidogrel before arrival. Fibrinolysis was performed in 19%, with a median time of 49 minutes and a maximum time limit of 86 minutes. 26% received beta-blockers, the median time was 343 minutes. Only 6% received painkillers. 60% were free from symptoms during their stay in the ER. 6% died while in the ER. 66% have been transferred to a cardiac intensive care unit. Only 24% have been transferred directly to the catheterization lab for angioplasty. The median time for discharge was 10 hours.

Conclusion: There is a lot to do to enhance the quality of care in our emergency department for patients who initially present with symptoms that refer to an acute coronary syndrome. Our delays of care are too long and don’t meet the guidelines, this is mainly due to the lack of experience among trainee doctors and the logistical challenges.


Jabrane MANSOURI (TUNIS, Tunisia), Kamel MAJED
08:30 - 17:40 #10945 - ACUTE DIGOXIN INTOXICATION: THE USE OF ANTI-DIGOXIN ANTIBODIES.
ACUTE DIGOXIN INTOXICATION: THE USE OF ANTI-DIGOXIN ANTIBODIES.

BACKGROUND

Chronic digoxin intoxication is more frequent than the acute one, however acute digoxin poisoning is more severe. Sinus bradycardia is the most typical disorder. Serum digoxin concentration is determined in emergency. Its therapeutic limit is set in 2 ng/mL.

 CASE PRESENTATION

A 59-year-old female patient, diabetic, hypertensive and mechanical aortic prosthesis carrier due to severe stenosis and chronic atrial fibrillation, was assisted by the emergency services presenting decreased level of consciousness and hypoglycaemia (33 mg/dL). The patient had voluntary ingested 45 tablets of digoxin (11.25 mg) and injected herself 400 IU of insulin as suicide attempt. Neutralizing treatment with activated charcoal and glucosmon was administrated.

At admission, the patient was haemodynamically instable, conscious with persistent hypoglycaemia. Electrocardiography showed slow atrial fibrillation with ST-segment changes suggestive of digitalis toxicity and frequent ventricular extrasystoles. Serum digoxin concentration was 23 μg/L.  

An empiric dose of digoxin-specific Fab antibody fragments and inotropes were administered intravenously and the woman was then admitted in intensive care unit, where a rapid clinical improvement occurred, thus allowing discharge in a few days.

 

DISCUSION

A high level of serum digoxin concentration is a factor to be considered for the administration of antibodies but it is not the only one. Its high cost determines a restrictive use, limiting its indications to cases of severe cardiac conduction disorder or severe hyperkalemia, with hemodynamic compromise with poor response to conventional treatment. In our case, the evident symptomatic clinic justifies the use of this drug,

 

CONCLUSION

1. Acute digitalis intoxication, although infrequent, must be considered within the differential diagnosis due to its potentially serious complications.

2. Digoxin-specific Fab antibodies should be considered when acute digitalis intoxication presents, although its indications are restricted and has only in-hospital use.


Marta DEL PUEYO PARRA, Isabel PÉREZ PAÑART, Victoria ORTIZ BESCÓS (Zaragoza, Spain), Román ROYO HERNÁNDEZ, Patricia ALBA ESTEBAN, María De La Peña LÓPEZ GALINDO
08:30 - 17:40 #11030 - Acute diplopia as the first manifestation of a right internal carotid aneurism.
Acute diplopia as the first manifestation of a right internal carotid aneurism.

Objective

To emphasize the importance of exploration and complementary imaging studies in patients whith diplopia consulting in emergency departments 

Method

A 49-year-old female with a history of fibromyalgia and dyslipidemia, who comes to the emergency place for binocular diplopia and pain in the right orbital region for 2 days. The patient is in treatment with clarithromycin for fever, headache and nausea during a week.  Exploration: slight limitation of lateroduction of the right eye (paresis of the VI pair) with alternating endotropy of 15º. Binocular diplopia in right lateroversion and inferoversion. Anterior pole and normal fundus. Rest of normal and normal neurological examination. COMPLEMENTARY TESTS: Skull CT: seal lesion with small bone erosion. Analytical blood without alterations. Lumbar puncture: no increase in pressure at the outlet of the fluid, Normal Blood Test, AngioTAC skull: Cavernous aneurysm of right internal carotid artery of 15x16mm in diameter. RM-angioresonance: Giant dysplastic aneurysm in the right internal carotid artery at the cavernous sinus level and left internal carotid aneurysm of 5mm diameter. DEFINITIVE DIAGNOSIS: Cavernous aneurysm of the giant right internal carotid artery and smaller size in the left internal carotid artery.

Results

The endovascular treatment of both aneurysms is indicated by flow-through stents, which are established without incident. In successive revisions, permeability of both stents is checked. From the clinical point of view, improvement of the muscular paresis with disappearance of the diplopia.

Conclusions

In the paralyzes of the IV cranial nerve, idiopathic cases or ischemia secondary to small vessel disease in elderly or diabetic patients are frequent. But it may be due to brain tumors or processes that produce increased intracranial pressure, nasopharyngeal tumors, infections, Wernicke's encephalopathy, multiple sclerosis, or aneurysms. Diagnosis of IV paresis is usually simple, but an etiological diagnosis is necessary to identify potentially serious lesions that require urgent specific treatment.

 


Rocio RODRIGUEZ BARRIOS (MALAGA, Spain), Ana PEREZ TORNERO, Rocio BORDALLO ARAGON
08:30 - 17:40 #11531 - Acute ischemic stroke following head injury: a case report.
Acute ischemic stroke following head injury: a case report.

Introduction:

Ischemic stroke is a rare complication of head trauma caused by vascular dissection. We report a medical observation who presented a post-traumatic acute ischemic stroke.

Case report:

A 72-year-old man, with no past history, presented to emergency department (ED) one hour after a head traumatic injury. He had an isolated head trauma without loss of consciousness after a domestic accident. At physical examination, he was conscious with a Glascow coma scale of 15 and no neurological abnormalities. During his stay in the emergency observational unit, he presented dysarthria and right hemiplegia, 6 hours later. Computed tomography scan of the brain with contrast injection, showed no anomalies. Magnetic resonance brain imaging (MRI), performed after 7 hours, revealed a fragmented left superficial sylvan stroke less than 6 hours old, occipital petechial contusion.

The patient was admitted to neurological intensive care unit.

The evolution was marked by the stability of the respiratory, hemodynamic states and regression of hemiplegia.

Conclusion:

It would be important to better manage traumatic brain injury including MRI, to prevent the risk of stroke. Recall that the consequences of a stroke are often dramatic, ranging from rapid death to severe paralysis.


Saloua AMRI, Sitafa COULIBALY, Alexandre CREPPY, Imene MEKKI (Tunis, Tunisia), Fredj KAHNA
08:30 - 17:40 #11194 - Acute kidney injury as first clinical manifestation of undiagnosed Schmidt’s syndrome. A case report.
Acute kidney injury as first clinical manifestation of undiagnosed Schmidt’s syndrome. A case report.


Vilma CADRI, Marjeta KERMAJ, Ariana STRAKOSHA, Matilda IMERAJ, Suela MUMAJESI, Ani BULLA, Edmond ZAIMI (Tirana, Albania)
08:30 - 17:40 #10716 - Acute meningoencephalitis in a patient with behavioral disturbance.
Acute meningoencephalitis in a patient with behavioral disturbance.

Acute meningoencephalitis in a patient with behavioral disturbance

Clinical case

Patient of 43 years, allergic to Pantomicina and Amoxicillin, with no medical history of interest that comes to the Emergency Department due to cognitive alteration with decreased consciousness level of 12 hours of evolution accompanied by weakness for ambulation after accompanying his daughter to the hospital. The previous day also attends a headache of 5 days of evolution with clinical improvement after medication administered and discharge from the home with a treatment regimen with Metamizol and Dexketoprofen.

Associated vomiting for 5 days.

Exploration

The patient is on a stretcher due to stunning

Conscious, oriented, little collaborator with lethargy, Regular general condition, muco-cutaneous pallor.

Head and neck, cardio-respiratory auscultation and abdomen without alterations

Neurological exploration with good response to orders and after mild painful stimuli, no loss of strength or sensitivity of upper and lower limbs. Impossibility to complete rest of exploration.

Supplementary tests

Blood analysis with leukocytosis with neutrophilia and slight increase of C-reactive protein values

Chest x-ray: normal

CT scan: no significant alterations

Cerebrospinal fluid puncture: 300 leukocytes, 10% polymorphonuclear and 10% mononuclear, 5 red blood cells, 59 mg / dl glucose and 176.1 proteins.

Negative cerebrospinal fluid culture.

JC: acute viral meningoencephalitis with no specific germ.

Evolution:

After requesting evaluation by Neurology we proceed to hospital admission with the performance of serial blood tests of negative LUES control and serology. Cranial Nuclear Magnetic Resonance is performed without alterations.

During her hospital stay, the patient remains hemodynamically stable and afebrile at all times, with favorable neurological evolution and significant improvement of the symptoms present at her arrival. At discharge, the patient is conscious, perfectly oriented, without signs of neurological focal- ity, without headache, nausea, or other associated symptoms.


Rafael INFANTES RAMOS (Málaga, Spain), Jose Ignacio VALERO ROLDAN, Carolina GARRIDO CANNING, Cristina FERNANDEZ- FIGARES MONTES, Maria Eugenia REYES GARCIA, Maria Victoria ALARCON MORALES
08:30 - 17:40 #11375 - Acute myocardial infarction with st segment-elevation: predictive factors of a fibrinolysis success.
Acute myocardial infarction with st segment-elevation: predictive factors of a fibrinolysis success.

Background: The management of myocardial infarction with persistent ST segment-elevation (STEMI) is based on coronary recanalization urgently. Fibrinolysis is the reperfusion approach commonly used in emergency department (ED).

The objective of this study was to identify clinical criteria predictive of fibrinolysis success among patients admitted for STEMI to emergencies within 12 hours.

Methods: We conducted a single- center, prospective, observational study. Inclusion of patients with STEMI thrombolysed by Tenectéplase (Métalyse ®). Fibrinolysis success was defined according to clinical and Electrocardiogram criteria. Multivariate study is used to identify the factors associated with thrombolysis success.

Results: Two hundred sixty-three patients were included. Mean age= 57 ± 16 years. Sex ratio= 6.96. Clinical history N (%): Hypertension 62 (23.6), diabetes 59 (22.4). The average time chest pain - emergency admission was 184 ± 126 min (30 min to 12 hours).The distribution of  STEMI N (%): inferior:  127(48.3) ; anterior, 45 (17) ; basal, 85(32) ; extension to the right ventricular, 59(22.4). The average success rate of thrombolysis was 72.2%. In multivariate analysis, the independents predictors factors of a fibrinolysis success were: the delay from onset chest pain to the ED visit less than 180 min [OR=1,5 ; IC à 95%= 0,99-2,26 ; p=0,05] and the delay for first medical contact to qualified ECG less than 10 min [OR= 1,5 ; IC à 95% = 1-2,26 ; p=0,05]. 

 

Discussion: Regarding the management of myocardial infarction with persistent ST segment-elevation in emergencies; the delays: from onset chest pain to the ED visit less than 180 minutes and for first medical contact to qualified ECG less than 10 min appears as independents factors of a fibrinolysis success.


Sarra JOUINI (Tunis, Tunisia), Hana HEDHLI, Rym HAMED, Wided DEROUICHE, Yasmine WALHA, Maroua MABROUK, Abderrahim ACHOURI, Chokri HAMOUDA
08:30 - 17:40 #11501 - Acute myocarditis with st+ segment change simulating myocardial infraction: a case report.
Acute myocarditis with st+ segment change simulating myocardial infraction: a case report.

Introduction:

Myocarditis, often caused by an infectious agent, may have a presentation mimicking that of acute myocardial infraction. The differentiation between acute myocardial infraction and acute myocarditis can be difficult. Electrocardiographic (ECG) changes and enzyme elevation are common in both.

We report a case of patient in whom clinical and ECG findings during the acute phase could have led to an erroneous diagnosis of myocardial infraction.

Case Report:

A 45-year-old male patient with no cardiovascular risk factor presented to the emergency department (ED) with an acute onset of asthenia associated with epigastralgia. He had normal physical examination findings. An ECG performed immediately showed the presence of  a 3rd degree atrio-ventricular block  and an elevation of ST-segment in leads V1 to V6 without a specular reflection in inferior leads. The chest X-ray was normal. The biological results showed high hypersensitive troponins at 24000 ng per liter, with no inflammatory syndrome (normal white blood cells and negative CRP). The diagnosis of ST-segment elevation myocardial infraction (STEMI) was made and the patient received a dual anti-platelet (aspirin and clopidogrel) and anti-coagulant (subcutaneous low molecular-weight heparin) medications.

The evolution was marked by the recurrence of the epigastralgia with electrical modifications in the percritical ECG with apparition of Q wave in anterior leads and persistence of the ST segment elevation. The patient was referred to cardiology department; the coronary angiography revealed no abnormality. A transthoracic echocardiogram done showed segmental abnormalities. The patient was discharged the next day with good outcome.

Conclusion :

The clinician is sometimes confronted with acute myocarditis presenting many of the features of myocardial infraction. This alternative diagnosis should be considered especially with young patient without coronary risk factors.


Hanen GHAZALI (Ben Arous, Tunisia), Ahmed SOUYAH, Aymen ZOUBLI, Anware YAHMADI, Soumaya MAHDHAOUI, Mahbouba CHKIR, Najla ELHENI, Sami SOUISSI
08:30 - 17:40 #11705 - Acute poisoning in elderly patients: epidemiological, clinical and management.
Acute poisoning in elderly patients: epidemiological, clinical and management.

Acute poisoning in elderly patients: epidemiological, clinical and management

Background: The demographic proportion of the elderly population is increasing continuously worldwide. The number of poisonings is also increasing among elderly people admissions in intensive care units. We carry out a study which aims to study the epidemiological, clinical and prognostic characteristics of elderly poisoned-patients.

Methods: It is a retrospective study spread over 63 months from 1st January 2012 to 31th March 2017 including all poisoned-patients over 65 years old admitted in a 22-bed teaching toxicological intensive care unit.

Results: 115 patients aged of 73 ± 7 among 6240 admissions were eligible with a prevalence of 0,018%. Sex ratio was of 1.16.  29.6 % of patients had psychiatric illness. Poisoning was accidental in 49.5% (n=58) of cases and it was about chemical submission for 3 patients. Pharmaceutics drugs were incriminated in 33,9 % (n=39), chemical substances in 57,4% (n=66), mixed poisoning in 3.5%(n=4) and Viper bite envenomation was observed in 6 patients. Among pharmaceutics drugs, the most often ones implicated in poisonings included cardiovascular drugs 14.8% (n=17), benzodiazepines in 11.3% (n=13), other psychotherapeutic drugs in 20% (n=23), theophylline in 3.5% (n=4), analgesics and anti-inflammatory drugs in 2.6% (n=3), and oral hypoglycemic in 3 patients. The most observed substances among chemical poisoning were pesticide in 22.5% (n=28), Carbon monoxide in 21.7% (n=25), herb poisoning 3.5% (n=4) and caustic products in 3.5% (n=4). One hundred and seven patients (93%) were symptomatic. Neurological signs were in 70,4 % (n=81) including consciousness loss in 54,8 % of cases (n=63), seizures in 4.3 % (n=5) and motor deficit in one patient. Digestive signs were present in 24.3% (n=28). As to the treatment, antidotes were administered for 18 patients, mechanical ventilation was required in 24.3% of cases (n=28) with a mean duration of 33 ± 20 hours. One hundred twelve of patients (95.7%) of patients were discharged alive from ICU with a mean delay of 3 ± 2 days.

Discussion: Poisoning is a significant problem in the elderly patients. Most cases were unintentional and may result from improper use of the product, improper storage of mistaken identities. Depression is also common in the elderly and suicide attempts are more likely to be rare in this age group.


Kahila OTHMEN, Khzouri TAKOUA, Aloui ASMA (Tunis, Tunisia), Hassouna MALEK, Ayari AYA, Youssef BLEL, Brahmi NOZHA
08:30 - 17:40 #11745 - ACUTE POISONING WITH METHOMYL LANNATE: EPIDEMIOLOGICAL PROFIL.
ACUTE POISONING WITH METHOMYL LANNATE: EPIDEMIOLOGICAL PROFIL.

Background:

Methomyl is a carbamate pesticide worldwide used in agriculture, particularly in our country. Acute poisoning in humans is rare but could be severe leading to death in few cases [1].

The aim of this study was to describe clinical features, management and prognosis in patients presenting with acute methomyl poisoning.

Methods:

It was a retrospective study extended over 8 years from January, 1st 2009 to April 2017, about all cases of acute methomyl poisoning admitted in our Intensive Care Unit. Methomyl poisoning was retained on a history of methomyl ingestion, clinical presentation and decrease of serum anticholinesterase activity.

Results:

One hundred patients aged of 28.2 ±14.6 years were eligible. They were 74 female and 26 male. Poisoning was by oral way in 98% cases in a suicidal attempt in 85%. The onset of clinical signs was rapid with an average delay of 13±24 mn.The most frequent symptoms were Miosis (n= 92), abdominal pain (n=63), Vomiting (n= 60), hypersialorrhea (n=36), Bronchorrhea (n=34), Coma (n=31), Diarrhea (n=27), fasciculation (n=27), acute pulmonary edema (n=17) and cardiac arrest in seven patients (7%). The most frequent biological abnormalities were hypokalemia (n=42), hyperlipasemia (n=9), hyperglycemia (n=24). Serum cholinesterase activity was decreased in 75% of cases with a median serum level on admission at 3374,50[140-14450] UI/L. Gastric lavage was required in 50 patients , atropine infusion in 96 patients, and assisted ventilation in 35 cases, among whom 13 patients suffered from acute respiratory syndrome. Vasoplegic shock was noted in 13 patients and acute pancreatitis in 9 cases among which 1 grade D and another grade E. Eight patients (8%) died during ICU hospitalization due to refractory hypoxemia in 62.5% cases and after resuscitation from cardiac arrest in 37.5% cases.

Discussion:

Methomyl poisoning is observed mainly in young female subjects. Muscarinic syndrome is the most frequent one. Serum cholinesterase activity could be normal due to its rapid and transitory action. Early intensive care management based on the administration of atropine is recommended to reduce mortality rate which remains high. 


Asma ALOUI (Tunis, Tunisia), Malek HSOUNA, Othmen KEHILA, Eya AYARI, Nozha BRAHMI
08:30 - 17:40 #11521 - ACUTE RENAL FAILURE OF OLIGURIC SEVERE IN PATIENT OF 32 YEARS WITH RABDOMIOLISIS SECONDARY TO CONSUMPTION OF INTRANASAL COCAINE.
ACUTE RENAL FAILURE OF OLIGURIC SEVERE IN PATIENT OF 32 YEARS WITH RABDOMIOLISIS SECONDARY TO CONSUMPTION OF INTRANASAL COCAINE.

Personal history:

 

No allergy to medications. Smoker 15 cigarettes / day. Casual beer drinker.

 

No previous surgical interventions

 

Current illness

 

A 32-year-old patient who comes to the emergency department for pain in the right renal fossa irradiated with a hypogastrium of 3 days of evolution accompanied by urine coluric dysuria, hyporexia and food vomiting in a number of 15 episodes per day.

The patient was studied for a similar picture two weeks prior with imaging tests (abdominal ultrasound and abdominal CT scan) that were normal.

 

On physical examination, hemodynamically stable patient with bilateral iliac fossa pain and positive bilateral percussion. Rest of physical exploration without pathological findings.

 

Complementary tests in emergencies:

 

Blood test:

Hemoglobin 14.4, Platelets 140, Leukocytes 16,000 (89% neutrophils) Prothrombin time 105% Glucose 101 Creatinine 6.38 mg / dL, Glomerular filtrate 11, sodium 131, potassium 4.80, chlorine 91, lipase 161, Creatin kinase 60469, Creatin kinase MB 170, GOT 1744, GPT 645, GGT 31 FA 69, total bilirubin 1.10 (direct bilirubin 0.40) Venous gasometry: pH 7.31 pCO 2 37, pO 2 49.9 Standard bicarbonate 18.7.

 

Urine Systematic: Positive Hematies, Positive Proteins

Biochemistry of urine: Proteins 2,4, Creatinine 350, Sodium 21, Potassium 46, Osmolarity urine 294.

 

Fraction Excretion of Sodium> 1: Prerenal Renal Insufficiency.

 

Abdominal ultrasound: Both kidneys of normal size and globulous aspect, with preserved cortico-medullary difference. Diffuse increase of cortical echogenicity suggesting nephropathy of prerenal origin, taking into account lso vomiting persistent).

 

During admission to the observation area, the patient denies having performed any over-exertion in previous days, as well as consumption of toxic substances, except alcohol. Nonetheless, urine toxicity analysis is carried out to evaluate positive values for cocaine.

Subsequently the patient is reinterrogated confessing cocaine use the previous day.

 

The patient was transferred to acute nephrology unit and after stabilization was discharged 4 days after admission with normalization of renal function

 


Manuel AGUILAR CASAS, Rafael INFANTES RAMOS (Málaga, Spain), Cristina FERNANDEZ- FIGARES MONTES
08:30 - 17:40 #11734 - acute theophylline poisoning: a clinical study.
acute theophylline poisoning: a clinical study.

Introduction: theophylline toxicity continues to be a major clinical problem in our country because its wide use for the management of asthma and various other respiratory diseases.it could be associated to a high risk of death related to cardiac toxicity.Our study aims to describe theophylline poisoning characteristics and correlation between the theophylline serum level and biological abnormalities.

Methods:during January 2011 to April 2017 we followed up all patients who had been referred to our Toxicological Center for theophylline poisoning.Were collected age,sex,supposed ingested dose and clinical manifestations of toxicity. All ingested form of theophylline were of prolonged liberation.A plasma theophylline concentration≥30 mg/l had been considered as reference for the diagnostic of poisoning.

RESULTS:89 cases of theophylline poisoning were reviewed. All cases represented intentional self poisoning.Patients were young (mean age:23 years[12-75]) and predominantly female (91%).Only 12% were known asthmatics and 4.5% had chronic obstructive airway disease.Sustained release theophylline preparations accounted for the majority of cases,the amount of ingested dose varied widely from 1000 mg to 18000 mg(mean 4512mg).In 87% of cases,theophylline was considered the sole drug involved,other drugs were reported in 13% cases.The delay between theophylline ingestion and emergency presentation ranged from 1 to 24 hours (mean delay:7.4 ± 5,3 hours).The initial mean serum level of theophylline was of 45.8 mg/l.Only one patient had a theophylline serum level of 156 mg/l.All patients had tachycardia and digestive symptoms (vomiting, epigastralgia).One patient had seizures and had been intubated.Hypotension was seen in one patient and was resolved under fluidloading.Electrolyte and metabolic abnormalities were frequent as hypokalemia in 66 patients (74%) with a mean of 3.07±0,3 Meq/l and lactic acidosis in 18.4% with a mean of 4±1,8,hyperglycemia in 69% cases with a mean of 8.6±2,8 mmol/L and Hyperleukocytosis in 69% cases (mean:13456± 4788).Hypokalemia appeared early in the course of overdose with a delay of 5 hours after ingestion).Gastric lavage was done in 5 cases,activated charcoal was required in 72% cases as a single dose, oral beta blokers in 35% of cases.In one patient who presented with shock, Norepinephrine was associated to fluid expansion.The mean ICU length stay was of 19.6± 13,5 h,less than 24 h in 80%.The analysis of correlations between biological abnormalities and blood theophylline concentrations showed a significant correlation between the blood theophylline concentration and the serum glucose level(p<0.001), hypokaliemia(r2=0,005),lactic acidosis level (r2 = 0,06) and the ICU length stay(p< 0.001).

Conclusion:With the widespread availability of theophylline preparationsand their extensive use for pulmonary conditions clinicians should be aware of the possible complications and risk of metabolic complications.


Malek HASSOUNA (TUNIS, Tunisia), Eya AYARI, Asma ALOUI, Hana FRADJ, Othmen KAHILA, Nozha BRAHMI
08:30 - 17:40 #11839 - Acute tramadol intoxication .
Acute tramadol intoxication .

ACUTE TRAMADOL INTOXICATION


Ben Jazia AMIRA, Khzouri TAKOUA, Fatnassi MERIEM, Aloui ASMA (Tunis, Tunisia), Kehila OTHMEN, Brahmi NOZHA
08:30 - 17:40 #11244 - Acute wound care in Pediatrics using tap water. A protocol that is not self-evident.
Acute wound care in Pediatrics using tap water. A protocol that is not self-evident.

Introduction: The cleansing of acute wounds does not currently have a standardised protocol in both our paediatric Emergency and Surgical consultation services. A preliminary survey found that a 9% saline solution was used in 70% of cases, wound debridement by soaking or swabbing the wound with an antisepsis in 90% of cases relating to wounds which are thoroughly dried. The data from scientific literature is not in line with our current acute wound care management.

Methods: Presenting our survey results to Nursing, Medical and Paramedical teams with reference to the data from literature reviews such as: the absence of benefit from using saline solution in comparison to tap (drinking) water, no advantage but rather same detrimental effect of using mild soaps, antiseptics, and wound drying techniques. Evidence-based guidelines were established and validated by Coordinating Centre for Health-care-associated Infections Control (CCLin). This study brought together other stakeholders including hospital hygiene unit, technical services and the pharmacy department.

Results: The validated protocol prioritize the use of tap water and the limitation of antiseptic use. The wash techniques must be made under a pulsated pressure of at least 8 psi (example 35 mL syringe and cathlon® gauge 19) and a sufficient volume of water (250 mL to 500 mL). The use of the drinkable water requires regular bacteriological monitoring, graphic identification of sinks used for hand and wound cleaning, the strict adherence of a purging technique of the water supply in the morning, a stringent cleaning of tap fixtures and shower heads and the bleaching of siphons. This protocol is accessible on the hospital website and to private medical practitioners.

Discussion and perspectives: A pre/post survey indicated a favourable response to the protocol without it being systematically implemented. Debriefing meetings were organised within the institutional framework. The mentoring of students/trainees served to advance these practices. Excluding the medical costs (study scheduled) our work highlighted the importance of an interdisciplinary and cross-sectional update of the acute wound care management taking into account the data published on a National level including the National Health Authority (HAS), and International level (professional societies and scientific literature).  With the institutional support, we value the quality of care and in-house training, for an informative update with an analytical and critical approach.


Nathalie THEYSSIER, Olivier MORY, Norayk DIRADURYAN, Olivier PHILBOIS, Julie GAGNAIRE, Blandine RIGAUD, Dr Abdo KHOURY (Besançon), Hugues LEFORT, Nicole DEFOUR
08:30 - 17:40 #11631 - Addressability of patients with stroke to the emergency services.
Addressability of patients with stroke to the emergency services.

Background. Implementation of new organizational strategies and tactics of diagnostics and treatment in the Strokes (Cerebrovascular Accident-CVA) from the last years are influenced by the aging of the population, increase number of repeated CVA, and high share of the contraindications of thrombolytic treatment

Materials and Methods: During one year there were analyzed 2805 calls of patients with CVA (1.01.15 – 31.12.15), the average age 68,0±12,9 years, including women 53% (1367) and men 47% (1213). It was assessed the structure of CVA, diurnal and seasonal addressability and diagnostics which mimics Stroke.

Results Ischemic CVA’s constituted 1983 (70,7%); 402 (14,3%) transient CVA’s; 228 (8,1%) other diagnosis and sequels of CVA; 181 (6,4%) hemorrhagic CVA and 11 (0,4%) subarachnoid hemorrhage. The most affected categories of age are 60-69 years (33,1%), 70-79 years (23,3%) and patients over 80 years were 17,6%.The study of diurnal and seasonal addressability attests us a high risk for days of Monday, Tuesday, Wednesday and Friday in which were registered 63%, in winter season were registered 27,4%, in spring season 28,4%, in summer season 24,5% and in autumn season 23,3% from the total number of CVA. A higher share of CVA are registered in the months of January (10,6%), March (9,2%) and December (8,6%). The diurnal study attests us that 56,6% from CVA appear between 08:00 – 16:00, 32,4% from 16:00 to 24:00 and 10,7% from the cases from 24:00 till 08:00 in the morning. The average length of call reception was 2 min, 46 sec ± 0,92 sec (interval 68 sec – 5 min 16 sec). During an hour from the appearance of symptoms 42,7% patients called. In 28,9% cases it was reported only one symptom, in 31,5% cases 2 symptoms and in 39,6% cases 3 and more symptoms. Only in 18,9% from the calls were present words which indicated CVA, fact which speaks about that only about 1 from 5 persons understands the CVA problem. The most frequent symptoms which were reported while calling to emergency were the speech disorder (27,3%)  paresis in limbs (19,8%), disturbances of consciousness (16,4%) and in 7,4% cases disturbances of sensibility. The diagnoses which mimics include: syncope 54 cases (2.1%), coma 46 cases (1,8%), sequels of CVA 75 cases (2,9%), epilepsy 28 cases (1,1%) and hypertensive encephalopathy 5 cases (0,2%)

Conclusions: CVA affects preponderantly the age over 60 years constituting 74%, including 17,6% for the age over 80 years. Days of week Monday, Tuesday, Wednesday and Friday and the months of the year January, March and December present a high risk of CVA .The most frequent symptoms were the speech disorder (27,3%),weakness or numbness of arm or leg (19,8%) and disturbances of consciousness (16,4%).The most common non-stroke conditions were syncope, coma and sequels of CVA.


Gheorghe CIOBANU (Chisinau, Moldova)
08:30 - 17:40 #11870 - ADEQUACY OF ORAL ANTICOAGULANT THERAPIES IN ATRIAL FIBRILLATION.
ADEQUACY OF ORAL ANTICOAGULANT THERAPIES IN ATRIAL FIBRILLATION.

Introduction

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice, about 25% of the world's population over 40 years age will suffer it across their life. AF is associated with a high risk of thromboembolic complications, fundamentally stroke, and oral anticoagulants have shown their ability to reduce this risk.

Objective:

To rate track clinical practice guidelines (CPGs) through the analysis of the indication of antithrombotic prophylaxis, and their relationship with oral anticoagulants therapies.

 

 Patients & Methods:

Descriptive, observational and retrospective study in a General Hospital in Murcia (Spain), which manage  a population of  200.000 people and 275 emergencies / day.  In the study 762 patients with AF from 1st October 2012 to 30th December 2013 were included. The analyzed variables are: average age, sex, CHA2DS2-VASc and HAS-BLED scores and previous anticoagulant therapies and at discharge. IBM® SPSS, version 21.0 was used as statistical program.

Results:

The sample under study was constituted by 64.59% and 35.61% of women and men respectively, with an average age of 72 years. The distribution of oral anticoagulant therapies received by the patients at home was: acenocumarol 28.25%, dabigatran 3.68%, rivaroxaban 2.37% , warfarin 0.66%, apixaban 0.13% , and without therapy received 63.34%. After an evaluation in the emergency room, The distribution of oral anticoagulant therapies prescribed at discharge change to: acenocumarol 27.4% , rivaroxaban 18.9%, dabigatran 12.6% and no therapy prescribed 29.96%.  The average of the CHA2DS2-VASc risk stratification score was 3.39, obtaining a score ≥ 2, 1 and 0 for the 82.76%, 9.20% and 8.02% respectively. And being the average of the HAS-BLED bleeding risk score 2.25, with a score of ≥ 3, 2, 1 and 0 for the 39.95%, 32.13%, 16.69% and 11.30% respectively.

Conclusions

In some situations, the decision to initiate anticoagulation is complicated because of the potential risks. According to the CPGs on anticoagulant therapy for the prevention of cardioembolic events in patients with AF, in our study, most patients received anticoagulant therapy at discharge according to CHA2DS2-VASc risk stratification score and HAS-BLED bleeding risk score correctly.


Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Danae FERNANDEZ-CAMACHO, Blanca DE LA VILLA ZAMORA, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain), Cesar CINESI GOMEZ
08:30 - 17:40 #11035 - Adequacy of the request for head CT scan after completion of a headache clinical decision rule.
Adequacy of the request for head CT scan after completion of a headache clinical decision rule.

BACKGROUND: The prevalence of clinically important abnormalities on head CT scans in patients presenting with a variety of neurologic complications in absence of head trauma varies from 8%-35%. In the last two decades, we have observed a sustained increase of CT scans use at the emergency department (ED). Accordingly, two main concerns have been growing: medical radiation exposure and cancer. The aim of this study is to ascertain the predictors of a positive head CT scan in patients with headache and demonstrate the feasibility of implementing a clinical decision rule (CDR) to improve the adequacy without compromising safety.

METHODS: After a bibliographic systematic review, a CDR was designed to improve the adequacy of the indication of head CT scans in patients attending an emergency department for headache. In the CDR, we have included the following alarm signs: age >60, neck pain/stiffness, loss of consciousness/neurological focus, onset during exercise, sudden pain, fever (not explained in clinical setting), meningism, HIV/immunosuppressed, progressive worsening/persistent headache and first episode in oncologic patient. If one of these was present, a head CT scan should be performed. In case of being negative, the indication of the performance was based on the clinical opinion of the emergency physician in agreement with the radiologist. The study and intervention was indicated to all patients who were referred for headache, as the main symptom, to the general emergency department of the Cruces University Hospital, a third level hospital in the Basque Autonomous Region (Spain). The data of the 6 months previous and after the implementation of the CDR were analyzed.

RESULTS: In all patients in the post-intervention phase in which the CDR was performed, there were no alarm factors at 37% and no head CT scan was performed in 99.5%, of whom 3.8% were reconsidered and in none of them was acute pathology. Of those who had alarm factors, no brain CT scan was performed in 6% and in none of them were acute pathology one month after the consultation in the emergency ward. The remaining 63% of the patients attending for headache with alarm signs head CT scan was performed to 94% and acute pathology was observed in 35%. Those patients who did not refer alarm factors (37%), a brain CT scan was performed to 0.5% of them and no acute pathology was observed. The pre-intervention inadequacy rate was 74% and 12% after the implementation of the CDR. Among those patients who consulted for headache in the pre-intervention phase, brain CT was performed to 40% versus to 30% post-intervention, with an estimated annual cost savings of 16,632 €.

DISSCUSSION: We observed that the CDR was 100% safe, and reduced costs and radiation exposure. Nevertheless we found a significant percentage of patients with alarm signs and non-pathological CT scan, which means that further adjustments should be made to the CDR, without compromising safety.


Silvia CARBAJO (Barakaldo, Spain), Gotzon IGLESIAS, Ana GIL, Daniel IZAGUIRRE, Leticia MUGICA, Gaizka BENGURIA, Lorea GALNARES, Leire ATILANO, Guillermo GONZALEZ, Aranazazu URRESOLA
08:30 - 17:40 #11177 - Adherence to the Belgian guideline for acute otitis media management in children at the Emergency Department.
Adherence to the Belgian guideline for acute otitis media management in children at the Emergency Department.

INTRODUCTION

The Belgian guideline for treatment of acute otitis media (AOM) in children does not recommend systemic antibiotics (ABs), except in clearly defined cases (Grade 1A). The guideline additionally allows using delayed AB prescriptions. If treatment is started, amoxicillin should be the first choice (Grade 1B). Poor guideline adherence has been reported before.

Our aim is to analyse adherence to the guideline in a paediatric emergency department (PED) in a tertiary teaching hospital.

 

MATERIALS AND METHODS

In a retrospective sample study, electronic health records of paediatric patients who presented in 2015 and were diagnosed with AOM were analysed regarding age, gender, diagnoses and AB use.

RESULTS

Of 17698 patients that presented to the PED, 875 (5%) were diagnosed with AOM as primary or secondary diagnosis, and after exclusion of patients already AB treated, 773 children were included.

Median age was 2 years (range 0–15), 436 (56%) were girls, 27 were <6 months old, 347 were 6-24 months old, and 399 were >2 years old.

Primary diagnosis was AOM (73%), cold (16%), pneumonia (4%), tonsillitis (3%), and other (5%).

We identified 297 patients (38%) for whom ABs were recommended: 27 (9%) because they were < 6 months old; 140 (47%) because they were 6 to- 24 months old and had severe symptoms, complications (mastoiditis, meningitis), or were not improving within 48 hours of the diagnosis; and 130 (44%) because they were >2 years old and had severe symptoms, complications, no improvement within 72 hours, or relapsing within 12 months.  Regardless of their age, high risk patients and children with persistent otorrhoea are also recommended to be treated with ABs.

Considering adherence to the guideline: of the 297 children for whom AB were recommended, 216 (73%) were indeed treated (3 received a delayed prescription), but 81 (27%) were not. For 476 children ABs were not recommended, yet 107 (26%) were started on AB (18 of whom received a delayed prescription. Overall, the guideline was not followed in 206 of the 773 patients (27%).

The guideline was most often violated in the group of 6-24 months old (104/347; 31%) than in both other groups of <6 months old and > 2 years old (respectively 7/27; 26% and 77/399; 19%).

When AB were administered (n=341) the guideline (proposing amoxicillin) was followed in 281 cases (82%); 29 (8%) received amoxiclav, 1 (0.3%) received trimethoprim-sulphamethoxazol, and 1 (0.3%) received macrolides.

As supporting treatment, 404 children (52%) received local drops containing antibiotics, 311 (40%) received local nasal decongestives, 252 (32%) analgetic eardrops, 252 (32%) local corticosteroids. The majority (n=632; 82%) received additional oral analgesia.

DISCUSSION AND CONCLUSION

Adherence to the Belgian guideline for AB treatment in paediatric acute otitis media patients is fair in the majority of cases, and most physicians at the PED treat AOM with the recommend antibiotic drug, but there is still room for improvement. 


Dr Gerlant VAN BERLAER (Brussels - BELGIUM, Belgium), Eveline VERSELE, Jolein HEUVELMANN, Ronald BUYL, Ives HUBLOUE
08:30 - 17:40 #11627 - Adrenal insufficiency as a differential diagnosis in septic shock.
Adrenal insufficiency as a differential diagnosis in septic shock.

Case report:

23 years old woman with personal history of autoimmune primary hypothyroidism.

The patient comes to the emergency department for two days of fever, vomiting and diarrhea accompained by deterioration in the cognitive level in the last few hours. She had hypoglycemia (42 mg/dl) that improved (134 mg/dl) after administration of glucagon and glucose serum.

Physical examination:

Blood pressure: 60/30 mmHg, temperature: 37.6º C, heart rate: 137 beats per minute, oxygen saturation 95% (fraction of inspired oxygen 31%).

Generally poor condition. Glasgow coma scale 13. Poorly perfused. Dry skin and mucous membranes. Cutaneous hyperpigmentation. Rhythmic heart tones, no murmurs. Breathing sounds conserved without pathologic sounds. Abdomen not tender to palpation without peritoneal irritation. Increased peristalsis. Without edemas or data of deep venous thrombosis in extremities.

Investigations:

In blood test highlight hyponatremia (124 mmol/L), hypokaliemia (3.4 mmol/L), metabolic acidosis (pH 7.3, HC03- 12.3 mmol/L), coagulopathy (prothrombin time 19.3 seconds), 11.700 leukocytes/mm3 with 8.700 neutrophils/mm3,  procalcitonin 50.16 ng/mL, C-reactive protein 5.46 mg/L.

The brain scanner suggests the possibility of diffuse cerebral edema. Rx thorax and abdominal CT without alterations of interest.

Evolution:

With the diagnosis of abdominal septic shock, treatment is initiated with intensive volume replacement, empirical antibiotic therapy with piperazillin/tazobactam and noradrenaline infusion . Despite this, hypotension persist and she presented deterioration of the level of consciousness (GCS 9) and respiratory worsening.

Patient is admitted to the ICU. She required orotracheal intubation and mechanical ventilation for acute pulmonary edema. With suspected adrenal insufficiency, treatment with hydrocortisone was started. A hormonal study was performed which showed low levels of cortisol (0.7 μg/dL) and ACTH highs (>2000 pg/mL). With a good posterior evolution, the patient was discharged five days later to the internal medicine plant to continue the study.

Conclusions:

It is important to keep in mind the adrenal insufficiency in a septic shock of poor evolution. Some data that may support the presence of this entity are refractory hypotension, hypoglycemia, hyponatremia and cutaneous hyperpigmentation.


Maria MARTIN SANCHEZ, Ana Maria CHUCHÓN (Ávila, Spain), Carolina RICARDO JIMÉNEZ, Angel MACIAS LOPEZ, Miguel OTERO SOLER, Gabriel BELLO
08:30 - 17:40 #10864 - Adverse events and registration practice in an emergency department.
Adverse events and registration practice in an emergency department.

Background: Admission to an emergency department at weekends has been associated with a higher risk of adverse events. However, limited information is available concerning this “weekend effect”. This study investigated numbers and types of adverse events occurred in an emergency department weekdays and weekends, and explore how the employees in the emergency department relate to these adverse events, including their perception of barriers to and incentives for reporting the adverse events.

Methods: This study followed a mixed-methods design consisting of 1) a prospective descriptive observational study, 2) focus groups interviews and 3) a questionnaire. The prospective descriptive observational study consists of two hundred twenty-nine adverse events, occurred in an emergency department at a Danish regional hospital, reported to the mandatory national reporting system during a two-year period (2014-2015). Based on results of four focus groups interviews with four nurses in each group, an anonymized self-completion questionnaire was developed and handed out to nurses and consultants in the department. The response rate was 64%. The material was generated in 2016.

Results: The analysis showed that most adverse events happen on weekdays (0.13 per shift) when compared to weekends (0.07 per shift). In all 27 % (61/229) of reported adverse events occurred in weekends. Different types of adverse events happen weekdays and weekends. Most of the adverse events happen on weekdays are related to 1) samples, patient examination and test results and 2) medication. Adverse events related to 3) treatment and nurse care and 4) information handover, patient responsibility and documentation happen more often in weekends. Furthermore, most adverse events happen between 2pm and 4pm. The focus group interviews and the questionnaire suggest that employees perceive reported adverse events as a tool to optimize the work processes and quality of patient care provided in the emergency department. However, because of workload, uncertainty and a lack of focus, they did not report all adverse events, which creates bias in the register data.

Conclusion: This study presented different tendencies in when and what kinds of adverse events are happening in an emergency department weekdays and weekends. Additionally, when only some adverse events are reported to the mandatory national reporting system this study also indicated problems in registration practices. Reporting adverse events has become an opportunity instead of a requirement. This highlights that high rates of reporting depend on the continual reinforcement and education of the aims on adverse events reporting to employees - a dimension that would benefit from leadership attention.


Iben DUVALD (Aarhus C, Denmark)
08:30 - 17:40 #11527 - Age and gender differences in patients with emergency department visits due to alcohol.
Age and gender differences in patients with emergency department visits due to alcohol.

Background: The excessive use of alcohol is a worldwide problem. Alcohol abuse is a cause of many health risks and contributes to an important part of the global mortality. In addition, alcohol-related problems cause significant financial costs for the society.

Objective: All patients of the emergency department of the Nikolaas General Hospital in Sint-Niklaas (Belgium) were examined whether the use of alcohol was a major cause of the current medical problem. This study focused on the importance of age and gender as risk factors.

Methods: From 14/09/2015 until 13/09/2016 a prospective observational study was completed: 97 pre-determined shifts of 12 hours each were randomly distributed. This could have been a day shift (from 7.00 am to 6.59 pm) or a night shift (from 7.00 pm to 6.59 am the next day).The weekend shifts were defined as starting at Friday 7.00 pm and ending at 6.59 pm the next Monday. Based on the routine approach of anamnesis, clinical evaluation and technical examinations the patients were divided into two groups: the intoxication group (the study population) and the control population. Blood or urine tests were requested because of the study.

Results: After exclusion of nine patients, 4693 patients were selected for further analysis. In total, 241 cases were alcohol-related (5.1%). The average age of the study population was 43.0 years. Males were overrepresented in both the general population (52.7%) and in the study population (61.4%). On weekend nights, alcohol-related emergency admissions raised to 12.5%. Between the different age groups there was not much difference, but in the study population 42.5% of the patients were between 41 and 65 years old. In the study population, no patient was younger than 15 years, but 25.4% of the study population was between 15 and 25 years of age and 11.7% was older than 65 years. Traumatic injuries were the most common alcohol-related complaint (46.1%). In the study population most patients stayed only for a short period of time in the emergency department, but a significant part was referred to a psychiatric ward (4.6%). Finally the study population made more frequently use ofthe ambulance servicesin comparison with the general population46.9% versus 19.9%.

Discussion: Gender is a significant risk factor for excessive alcohol consumption. The age of a patient plays a less prominent role. Alcohol however is not only a problem among young people. Middle-aged men report themselves often with alcohol-related problems at the emergency department. Because 5.1% of all patients had alcohol-related symptoms, the providing of early detection and treatment of these problems is important. It is also important to focus on older patients. However, our study design is bias-prone, because it was not a continuous registration. Therefore, a prospective study that includes a whole year of registration is needed to complement the present data.


Andries COPPEN (Belsele, Belgium), Jorn DAMEN, Jolien DE GRAEVE, Julie DE CREM, Sebastien HEYNDRICKX, Valerie LEMMENS, Heleen FRANÇOIS, Paul CALLE
08:30 - 17:40 #10852 - Age, Gender, Nationality, Weekday, Mode of Referral - Sociodemographic Transitions in Patients in a Large City Emergency Centre over a Period of 10 Years.
Age, Gender, Nationality, Weekday, Mode of Referral - Sociodemographic Transitions in Patients in a Large City Emergency Centre over a Period of 10 Years.

Popular demand for high quality care has increased in recent years. This is also the case for medical services and support at all times of the day and night. During the last ten years, there has been a marked increase in the demands on hospital emergency hospitals, particularly in western industrial countries.

Aims of the study: The present retrospective study investigates how the demands on a large Swiss university centre have changed over a period of 10 years; patient numbers are differentiated by age, gender, nationality, weekday and mode of referral.

Methods: A retrospective analysis was performed of the data of the patients admitted to the Emergency Centre of Bern University Medical Hospital – the Inselspital – in the ten year period from 2004 up to and including 2013 and who were treated as emergency patients.

Results: A total of 264,272 patients were included in the study. It was shown that there was an uninterrupted annual increase from 23,555 patients in 2004 to 34,918 patients in 2013 (+48%). For the whole period, a mean of 42% female and 58% male patients were treated. The gender distribution was constant over 10 years. As regards the age distribution, the values were markedly higher for younger patients, with a peak at 26 years of age. The age group with the most patients was for the 20-29 year olds, with 19% of the total (50,636 patients). From the peak for the 26 year olds, the mean age decreased continuously up to the 80 year olds and then dropped sharply for the over 80s, who made up 8% of the total patient population. The greatest increase was from 2012 to 2013 and was observed in each age group. The relative increase over the 10 years was greatest for patients aged over 90 from 8 to 14%. Most self-referrals were during the weekend or on Mondays. GPs most frequently referred on Mondays and Fridays and internal departments on Fridays. Referrals by the ambulance service, external hospitals or the police were evenly distributed throughout the week.

Conclusions: In the coming years emergency centres will have to adapt to the continued increase in patient numbers. For the organisation and optimisation of patient care in emergency centres, it is important to know that the weekdays with the highest patient numbers are Monday – with mostly younger patients – and Friday – with mostly older patients. Most patients refer themselves. The number of self-referrers is also continuing to climb.

It was also found that emergency centres must prepare for a marked increase in the number of geriatric patients. In particular, the group of very old patients of over 90 will increase. For this reason; emergency centres must prepare themselves to provide adequate care to this group of patients.

These trends will continue, so that it is essential to consider the sociodemographic structure of a region when planning the availability of emergency medical care.


Christian BRAUN (Bern, Switzerland), Cornelia GNÄGI, Meret RICKLIN, Aristomenis EXADAKTYLOS
08:30 - 17:40 #11953 - Agenesis of the corpus callosum revealed by a cranial trauma seen in the ER: About a case.
Agenesis of the corpus callosum revealed by a cranial trauma seen in the ER: About a case.

INTRODUCTION: 
Corpus callosum agenesis (CCA) is the most common form of cerebral malformations with an incidence of 0.05 to 0.7% in the general population. It is characterized by the absence of the main inter-hemispherical commeasure: the corpus callosum. In 50% of the cases, the CCA is isolated; it can be symptomatic or asymptomatic.
CASE Report: 
H.B.S 26 years old, a factory worker, smoker, with no significant medical history, was sent to the emergency by the civil protection following a road accident. He was hit by a car while walking. The trauma was a dual component, traumatic brain injury with initial loss of consciousness and altered consciousness, and closed thoracic trauma. At admission, the patient was confused, with a GS of 8, and a vertical occipital wound of 4 cm and a right per orbital ecchymosis. His hemodynamic state was stable, the blood pressure was 113/69 mmHg and π at 74 cy/min. At pulmonary auscultation there was a diminution of the vesicular murmur on the left. The abdomen was supple and painless within the limits of the examination. The patient was intubated from the start because of neurological distress, and he benefited from an urgent resuscitation with monitoring of blood pressure and ACSOS targets. The thoracic Xray in bed and ECG was without anomaly. An emergency Bodyscan has demonstrated colpo-cephaly with thinning of the frontal horns in relation to an agenesis of the corpus callosum and intraventricular haemorrhage at the intersection and occipital horns.

DISCUSSION: 
Agenesis of the corpus callosum is a rare cerebral malformation usually detected in children. In a study by Lemesle et al, epilepsy was the most frequent mode of revelation. In the absence of epilepsy, the discovery may be fortuitous; It is revealed then by the neuroradiological explorations. These patients generally have no mental retardation or inter-hemispheric disconnection syndrome. Facial malformations are minimal.
CONCLUSION: 
Agenesis of the corpus callosum may be latent and can only be revealed by epilepsy. Regardless of age, the prognosis appears to be related to the associated malformations, which are incriminated in the genesis of epileptic seizures and neuropsychic disorders observed.


Zied GUERMAZI (Trévenans), Nour El Houda NOUIRA MZAHMA, Elmoez BEN OTHMANE, Sana LAHMAR, Meher ARAFA, Nadia ELWAFI, Mamoun BEN CHEIKH
08:30 - 17:40 #11097 - Air pollution and daily emergency department admissions for chronic obstructive pulmonary disease in a Croatian clinical hospital.
Air pollution and daily emergency department admissions for chronic obstructive pulmonary disease in a Croatian clinical hospital.

Background. Acute exacerbation of chronic obstructive pulmonary disease (COPD) is one of the most common reasons for hospital admissions worldwide. In the last few decades, atmospheric pollution has been identified as a cause of COPD exacerbations, but recent results suggest that adverse health effects of air pollution exist at levels of pollutants around and below the current national and international air quality guidelines and standards. Visits to the emergency respiratory department can be a direct result of short-term exposure to air pollution. The aim of this study was to investigate the short term relationship between air pollution, meteorological variables and the daily number of ED admissions for COPD.

Methods. We conducted an ecological time-series study. Daily records of COPD ED visits for patients older than 30 years were obtained from Clinical hospital Sveti Duh, Croatian teaching hospital, from 1 January 2010 to 31 December 2016. Demographic characteristic, incidence rate of ED, reasons for visit, length of ED stay, factors such as day of week, and season were analyzed retrospectively. Daily measures of ozone (O3), nitrogen dioxide (NO2), carbon monoxide (CO), sulfur dioxide (SO2) and particulate Matter (PM10) were extracted from the Croatian Air Resources Board database.

Results. We enrolled 2553 COPD-related ED visits for the study period (2010-2016), predominantly male 61,1%, mean age 73,94 years. Those aged 65 years or over accounted for 77,84% of all treatment periods with monthly higher deviation in comparison with younger age group. COPD-related ED visits showed a distinct seasonal pattern, in March exceeding the mean monthly average by 18,61%. The monthly figure continued to be above average in the early spring but started to decline markedly during summer. The winter peak in admissions and summer through were seen in both sexes, but the monthly variation was more notable among the man. Analyze the effect of season on recurrent exacerbations, showed 54% of first exacerbations during October to March were followed by a second exacerbation within 8 weeks, whereas during April to September this fraction was 46%. We observed a positive linear association between PM10, SO2, NO2 and CO, and a negative correlation was noted with O3 and temperature. COPD-related ED visits showed significant correlations with primary pollutants, but not with CO. There were also significant correlation with temperature, but not with absolute daily temperature variation or humidity.

Conclusion. The results confirm that air pollution is associated with daily admissions for COPD. We identified a sharp increase in admissions starting in November and peaking in March of the following year. These results indicate that air pollution affects health in a gender- and age-specific manner and should be considered a relevant risk factor that exacerbates COPD in urban environments.


Ivan JURIĆ (Zagreb, Croatia), Višnja NESEK ADAM
08:30 - 17:40 #10989 - Ambulatory emergency care : improving patient experience and departmental flow through service development.
Ambulatory emergency care : improving patient experience and departmental flow through service development.

Introduction: It is widely reported that pressure on the NHS has reached an all-time high, with Emergency Departments (ED) particularly stressed. Performance against the government 4 hour breach target is at a 10 year low. Reasons for this include increased service use; patient attendances, and decreased discharges secondary to lack of social care provision. On a practical level, Emergency Departments are increasingly overcrowded due to exit block.

To combat this, AEC (Ambulatory Emergency Care) was developed as a National initiative. St Helens and Knowsley Hospital (STHK) enrolled in cohort 3 in 2013. AEC aims to streamline patient treatment and deliver care on an outpatient basis, avoiding unnecessary admissions overnight.

Together with inpatient specialities STHK ED has developed several pathways to manage conditions traditionally requiring admission. Pathways include dedicated next day radiology slots and speciality review clinic appointments. It is hoped that reduced admissions and optimised patient care will lead to improved flow in the ED.

In July 2016 a clinical area was repurposed to house AEC. A 4 bedded Observation ward bay was transformed into a seated area for 8 patients. This was a dedicated area for AEC, logistically unifying it’s components.  It was envisioned that a space for pathways and staff would further increase efficiency and turnover. To investigate this we audited patient number and space occupancy pre and post AEC.

Method : Retrospective audit of bed space occupancy, total attendances and average length of stay. Results correlated and mapped against departmental attendances and breaches.

Results : Prior to relocation of AEC, average bed occupancy was one patient per 24 hour period, with average though put of 4 patients in 24 hours. Post repurposing and relocation attendances varied from 28 -40 patients in 24 hours, 4.8 patients per space.

Breach impact was calculated as a 5% reduction in numbers of breaches; and was the single most effective intervention at reducing breaches.

Discussion : Often compared to introduction of day case surgery; AEC involves a paradigm shift – “can we deliver the same care at home?” “No patient should spend an unnecessary night in hospital” Our audit shows increased patient throughput, increased flow and improved ED performance. Of note, is that the audit was performed when AEC ran between 0900- 1700, a fully running 24 hour service is likely to yield greater results. Our aim is to further develop this service and repeat our audit.

 

 

 

 

 


Peggy MACHIN, Mark GUEST, Dan MULHOLLAND (Ipswich, United Kingdom), Emily HARGREAVES
08:30 - 17:40 #11388 - Amyand's Hernia: A Case Report.
Amyand's Hernia: A Case Report.

Background: Amyand hernia is defined as the presence of normal or inflamed appendix vermiformis within hernia sac and constitutes 1% of all inguinal hernias. Most of the cases have right side clinic. Left sided Amyand’s hernia is even less common.

Case:A sixtysix year old male patient was admitted to our clinic with a 2-year history of swelling in the left groin and acute pain, nausea and vomiting during the last 3 hours. There was nonreducible inguinal hernia in the left inguinal region on his physical examination. There was no systemic finding other than rhonchi in lungs with a medical history of COPD. He didn’t also have any operation history. Serum laboratory values were unremarkable with normal range leukocyte count WBC: 9300/mm3. He was taken to urgent surgical exploration. In the operating room, the indirect herni sac descending to scrotum was explored. Vermiform appendix, cecum, and some small intestine segments, which form part of the sac wall were observed in the hernial sac (Figure 1 and 2). Appendectomy was performed and then hernia defect was repaired with prolen mesh by Lichtenstein method. After postoperative care, the patient was discharged for outpatient follow-up.

Discussion: Amyand’s hernia is diagnosed during surgery in patients admitted to emergency departments and general surgery clinics with a pre-diagnosis of incarcerated inguinal hernia. By reporting a case that was hospitalized and underwent to urgent surgery due to left-sided incarcerated inguinal hernia from our emergency department and surgically detecting acute appendicitis in the hernial sac, we aimed to remind the diagnosis of Amyand’s hernia which is a very rare clinical entity in the literature.

Conclusion:Amyand’s hernia is a very rare presentation of appendicitis and correct preoperative diagnosed is almost impossible for it.  


Faruk PEHLIVANLI, Oktay AYDIN, Gökhan KARACA, Selçuk MISIRLIGIL, Oğuz EROĞLU, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #11307 - An Amputated balloon.
An Amputated balloon.

Introduction: - Tracheobronchial injury (TBI) can result from non-penetrating or penetrating trauma. Tracheal disruption is a rare occurrence and is seen in 14% of the penetrating neck and chest trauma cases and 0.34-1.5% of all blunt trauma cases including adults and children. In 8% of the injuries, the lesions are complex occurring in more than one location, with more than one type of lesion or on both of the main bronchi and trachea. Of the patients who die of TBI, most of them do so before receiving emergency care either due to airway obstruction, exsanguination, or from injuries to other vital organs. Mortality among survivors who reach the hospital may be as high as 30%. We report a case of 24 years old male surviving such an injury.

Case report: - An, otherwise, healthy 24 years old male presented after sustaining an accidental injury while operating heavy machinery at work place. He was primarily treated outside and had an endotracheal tube in situ. There was an open chest wound near right axilla on chest and avulsion injury over frontal scalp. Patient was hemodynamically unstable. His heart rate was 145 beats per minute, respiratory rate of 40 cycles per minute, SpO2 of 57% with O2 at 15 liters per minute and blood pressure of 102/62 mmHg. Patient had impaired mental status. There was extensive subcutaneous emphysema extending from neck up to lower abdomen. After initial primary treatment patient had undergone computed tomography of head to abdomen which was suggestive of discontinuity involving right main bronchus from its origin for a length of approximately 3cm with rent of 6.7mm in trachea, left sided moderate pneumothorax and right sided marked hemopneumothorax with complete collapse of right lung and left lung contusions, pneumomediastinum, pneumopericardium, pneumoperitoneum, multiple rib fractures of right and left side, multiple facial bone fractures, bilateral clavicle fractures. Management included bilateral intercostal drainage in emergency department. Bronchoscopy guided one lung ventilation to left lung followed by surgical repair in form of right thoracotomy with re-implantation of right main bronchus to carina was performed. No obvious air leak noted after switching on to normal double lung ventilation. Patient’s stay in hospital was uneventful and discharged after 28 days

Discussion: -  Tracheobronchial injury appears to occur approximately in 2-9% of individuals sustaining penetrating injuries. In terms of clinical manifestations, hemorrhagic shock with systolic blood pressure less than 80 mmHg and heart rate more than 120 beats/min are best predictors for poor outcome. Hypoxemia is shown not to be a poor prognostic factor. Paramount in managing suspected partial tracheal transections is to avoid converting the injury to a complete transection. Positive pressure ventilation or an unguided placement of a large-bore tracheal tube can complete a partial tracheal transection. 


Dr Ketan PATEL (Ahmedabad, India), Anjali PATEL, Rignesh PATEL, Pritish SOLANKI
08:30 - 17:40 #11611 - An atypical emergency case – Abundant UGIB due to severe thrombocytopenia amid septic shock in a patient suffering from small B-cell non-Hodgkin’s lymphoma.
An atypical emergency case – Abundant UGIB due to severe thrombocytopenia amid septic shock in a patient suffering from small B-cell non-Hodgkin’s lymphoma.

Background: Upper gastro-intestinal bleeding (UGIB) is a majorly urgent medical condition involving the upper digestive tract up to Treiz’s angle, usually expressed through melena and/or haematemesis. The main causes for UGIB are gastric ulcer and duodenal ulcer, these two disorders being responsible for around 70% of the total UGIB cases. Gastritis, on the other side, presents a relatively low risk of bleeding, around 15%, rarely life-threatening. Esophageal pathologies (like esophageal cancers, diverticular diseases, esophageal erosions) and hiatal hernia represent just around 2% of all UGIB, whereas liver cirrhosis complicated by esophageal varices raises the percentage to 15-17%. Mallory-Weiss syndrome consists of just 3% of the cases, while gastric tumors around 5% of the total upper gastrointestinal bleedings. There are also atypical cases of UGIB like our patient, R.I., aged 66, accusing an acute episode of abundant UGIB, complicated by septic shock, in association to post-chemotherapy medullary aplasia related to malignant small B-cell non-Hodgkin’s lymphoma.

Methods: This is a retrospective clinical case study from 2015, involving a patient presenting, amid immunosuppressive background pathologies, namely small B-cell non-Hodgkin’s lymphoma CD20+ follicular I/IInd degree, diagnosed on the 3rd of June 2014 through left laterocervical lymph node biopsy, septic shock from Klebsiella pneumoniae, complicated by an abundant episode of UGIB – most probably stress-related, the contributory factor being severe thrombocytopenia, of 2000 thr/mm3. The patient was admitted to the Clinical Emergency County Hospital of Sibiu, considered in critical state and received emergency treatment aimed towards stabilizing his general condition. The therapy, which included sodium bicarbonate administration on the nasogastric tube in parallel to famotidine, intravenously, for the first few hours, was essential, because the pH of the gastric lumen tends to decrease below 4. If this happens, the hemorrhage reappears, due to dissolution of the thrombi.

Results: The blood samples collected during the UGIB episode revealed 2000 thr/mm3 (n.r. 150,000-400,000/mm3), hemoglobin of 9.3 g/dl (n.r. 13-16 g/dl), hematocrit of 28.1% (n.r. 37-47%), SBP - 70 mmHg. Following thrombocyte and erythrocyte mass transfusion, sodium bicarbonate and famotidine administration through the nasogastric tube, the blood parameters of the patient have known positive modifications as follows: thrombocytes – 22,000/mm3, Hb – 10.7 g/dl, SBP 120 mmHg, whilst the bleeding was stopped.

Discussions: Although patients with primary or recurrent UGIB are usually known with chronic gastrointestinal pathologies (of the esophagus, stomach or duodena), and/or decompensated liver cirrhosis, other atypical life-threatening situations may occur, worthy of being taken into account, just like the one presented afore.


Maria-Victoria ARDELEANU, Constanta STOICA (Sibiu, Romania), Bogdan-Alin ARDELEANU, Petruta-Ioana CIOROGARIU, Gabriela Diana DENDRINOS, Romeo Gabriel MIHAILA, Cosmin Constantin PITURLEA, Irina PRISACARIU
08:30 - 17:40 #11359 - An atypical presentation of an uncommon diagnosis: epidural abscess.
An atypical presentation of an uncommon diagnosis: epidural abscess.

Background:

Epidural Abscess (EA) is an uncommon disease with a wide variety of clinical presentations. The disease's triad of back pain, fever and neurological deficits is seldom present. EA incidence has has risen from 0.2/10,000 to 3/10,000 in the United States, but it is still missed diagnosed in 75% of cases during the first medical encounter. The delay in diagnosis and treatment leads to permanent neurological damage and increases mortality from 2-20%. 

Case Description:

We present the case of a 35 -year-old diabetic male who walks into Emergency Department (ED) with 1 week of worsening chest pain with associated palpitations. He also reported sporadical  back discomfort that irradiated from chest onto trapezius. Patient denied fever, chills, weakness, urinary difficulty or any other classic symptoms that would suggest EA.

Clinical Findings:

Physical examination was remarkable for tachycardia of 115 beat per minute without fever. All labs, chest X-Ray, bedside cardiac sonogram and chest CT Angiogram were normal. Tachycardia nor chest pain improved after analgesia or IV hydration. Patient was consulted due to intractable symptoms, eventually being discharged after unremarkable observation period. He was admitted 2 days later for, when he returned with initial complains in addition to jaundice. On day 4 of admission patient developed lower extremity weakness and urinary retention.Thoracic  Magnetic Resonance Imaging (MRI) showed T3-T8 EA. Patient was managed medically due to extent of irreversible damage.

Conclusion:

This patient had a rare presentation of EA since chest pain and tachycardia were the predominant signs and symptoms. These are not widely described in the literature as initial complains. Increased awareness is essential for rapid diagnosis, especially when other more common diagnosis are excluded. Erythrocyte sedimentation rate (ESR) is the only laboratory consistently found elevated. It is increased in 95% of cases, therefore while unspecific, it is clinically useful. Emergency physician can use ESR and CT myelogram in settings where MRI is not available. This, plus awareness of such challenging diagnosis can decrease its catastrophic consequences.


Gerald MARIN-GARCIA (Carolina, Puerto Rico), Fernando SOTO-TORRES, Maria RAMOS-FERNANDEZ
08:30 - 17:40 #10943 - An audit to look at how ambulatory emergency care unit has improved the management of patient’s presenting in urinary retention to the emergency department.
An audit to look at how ambulatory emergency care unit has improved the management of patient’s presenting in urinary retention to the emergency department.

Background: Acute urinary retention is the inability to voluntary pass urine. It is a common urological emergency seen in the emergency department. Affected patients often present in distress and discomfort. Patients with suspected acute urinary retention have a bladder scan performed to confirm the diagnosis. A volume of 300ml or greater with inability to void suggests urinary retention. The STHK trust KPI for management of acute urinary retention aims for 90% of patients to be catheterised within 1 hour of triage. The emergency ambulatory care unit (AEC) is an area of the emergency department in which patients identified matching a certain criteria can be sent straight from triage to be seen by a nurse and doctor team. Acute urinary retention is one of the selected cases seen in AEC.

Method: Retrospective audit of patients attending AEC with acute urinary retention over a 3 month period. Searched electronic case notes to determine time to catheterisation against the time of arrival to AEC. Obtained data from electronic database for patients attending the emergency department with the inability to pass urine over a one month period prior to the opening of the AEC. Searched electronic case notes to find the times of triage and catheterisation.  

Results: 15 patients attended the emergency department with inability to pass urine in January 2016 prior to the opening of AEC. 40% of these patients were catheterised within 1 hour of triage. 20 patients attended AEC over a three month period in acute urinary retention. 55% of these patients were catheterised within 1 hour of their arrival on AEC, only 1 patient required admission, discharge rate of 95%.

Discussion: Acute urinary retention is a common presentation to the emergency department. The hospital KPI is to catheterise these patients within 1 hour of triage. Unfortunately this target has not been met on review of this audit, however there was some improvement toward this target seen with the introduction of the AEC. Delays to this target are often a result of a busy department in which problems arise from space to see patients, longer waiting times and engaged use of the bladder ultrasound to confirm diagnosis of patients. The AEC department aims to reduce this problems with a more stream line approach to patient with acute urinary retention, once more established in the trust the target of 90% of patients catheterised within an hour of triage should be met. Changes that can be implied to help achieve this target is for greater awareness and education of the usage of AEC, ideally the addition of a new bladder ultrasound machine designated to the either the triage or ambulatory care area therefore allowing quicker identification of urinary retention, the addition of a second triage nurse in triage will allow for these patients to be identified and assessed more quickly, the presence of a doctor on AEC for 24hr period (currently 12rs covered). We aim to re-audit once all these measure are in place.


Dan MULHOLLAND (Ipswich, United Kingdom), Mark GUEST, Peggy MACHIN, Emily HARGREAVES
08:30 - 17:40 #10872 - An evidence-based study: evaluating the antithrombotic therapy for venous thromboembolism disease in the Gaza-Strip hospitals.
An evidence-based study: evaluating the antithrombotic therapy for venous thromboembolism disease in the Gaza-Strip hospitals.

Background:

Since venous thromboembolism (VTE) disease is a life-threatening medical condition requiring urgent evaluation and treatment, this is the first clinical audit to evaluate adherence of clinicians to international guidelines for antithrombotic therapy for VTE disease.

Methods:

This was a retrospective clinical audit conducted from January to December 2016. Files of patients admitted to European Gaza Hospital and Al-Shifaa Hospital were reviewed and compared to the standard of the American College of Chest Physicians (ACCP) Guidelines 2016.

Results:

In total, 95 cases were identified.  The mean age was 44 ±17 years and that of duration of hospitalization was 6 ± 3 days.  Interestingly, 43% of patients were males and almost half of the patients (n=46) had no co-morbidities. We were able to identify 10 different categories of VTE.
Proximal deep vein thrombosis (DVT) was the most frequent category (46.3%). Over 80% of patients with proximal DVT were treated with extended therapy (no scheduled stop date) using vitamin K antagonists (VKA). Half of these patients were not switched to aspirin after 3 months of anticoagulation therapy as indicated in the ACCP guidelines and none of them was tested for D-dimer level after 1 month of stopping the anticoagulant. Recurrent VTE on VKA or novel oral anticoagulants (NOAC) was the second most frequent category with 20% (n=19). Surprisingly, 18 of these 19 cases were continued on extended therapy using a higher dose of VKA rather than being switched, even temporarily, to low molecular weight heparin (LMWH) as suggested by ACCP guidelines while only 1 case was switched.  Cancer-associated thrombosis was the third most common category (6.3%). All patients in this category were treated with extended therapy using VKA rather than LMWH as suggested. Other categories identified were similar in terms of deviating from the guidelines and choosing the anticoagulant.
Among all cases who received extended therapy, only 48.4% were reassessed for continuing use of treatment at periodic intervals. However, 3.2% used compression stockings, which are not suggested.

Discussion:

The results of this audit reflect the fact that the antithrombotic therapy for VTE does not comply with the standards of the ACCP guidelines. This could be attributed to the shortage of NOAC and unaffordability of LMWH at governmental hospitals. Another reason is the lack of local guidelines and awareness of the international guidelines. Furthermore, the poor documentation system causes loss of data and physician orders which in turn causes less compliance from the patients and deviation from the standards and guidelines. Therefore, there is an urgent need for the development of local guidelines as well as promotion of knowledge of evidence-based practice among clinicians. In addition, an improvement of the current documentation system should be implemented as soon as possible to facilitate the process of evaluating the clinical practice in future.


Mohamedraed ELSHAMI (Gaza, Israel), Zaki ALYAZJI, Anas ISMAIL, Bettina BOTTCHER
08:30 - 17:40 #10995 - An evidence-based Study: evaluating the management of acute heart failure in the Gaza-Strip hospitals.
An evidence-based Study: evaluating the management of acute heart failure in the Gaza-Strip hospitals.

Background:

Acute heart failure (AHF) is a life-threatening medical condition requiring urgent evaluation and treatment.  This is the first clinical audit to evaluate the adherence of clinicians to international guidelines for management of AHF.

Methods:

This was a retrospective clinical audit conducted from January to December 2016. Two-hundred files of patients admitted to Nasser Hospital (n=74) and Al-Shifaa Hospital (n=126) were reviewed and compared to the European Society of Cardiology (ESC) Guidelines 2016.

Results:

The mean age of our sample was 66 ± 13 years. Fifty percent of patients were females and 96% had co-morbidities including hypertension, DM and heart disease. Shockingly vital signs were poorly documented (51% temperature, 59% pulse rate, 71.5% respiratory rate and 13% blood pressure) and SpO2 in only 69.5%. From the available data, at time of presentation, 40% had a high blood pressure, 37.7% had an SpO2 < 90%, 50.5% were anemic and 33% had leukocytosis. ECG, chest x-ray and echocardiography were done in 94.5%, 48.5% and 45%, respectively. Creatinine and urea levels were obtained in 93.5% and 89% with elevated values observed in 45.5% and 96.6%, respectively. Electrolytes (Na+ and K+) were measured in 63% of cases, glucose level in 88% but only 10% had arterial blood gases measured and 2.5% TSH level. It was found that 21.4% had hyperkalemia and 77.3% had hyperglycemia. Cardiac troponins were only done in 5.5% while 66.5% of patients had CKMB measured and BNP level wasn’t utilized at all. Although 37.7% of patients had an SpO2 < 90%, it was surprising that only 12.5% received oxygen therapy. Intravenous furosemide was used in 69% and opiates were only administered to 30%. Vasodilators were given to 46.5% where systolic blood pressure was > 90 mmHg in 89.1% of them. Beta blockers (BB) were used in 57% (70.2% bisoprolol, 29.8% carvedilol). It was noted that BB were given to 2 hypotensive patients, which is not consistent with ESC guidelines. Digoxin 0.25 mg was given in 28.5% of which 53.4% had atrial fibrillation. Venous thromboembolism prophylaxis was administered to 70%.

Discussion:

The results of this audit reflect the fact that the management of AHF does not comply with the ESC guidelines. This could be attributed to the lack of local guidelines and unawareness of international guidelines. Furthermore, the poor medical record and registry systems cause loss of data and physician orders which in turn causes more deviation from the recommended guidelines. Therefore, there is an urgent need for the development of local guidelines as well as promotion of knowledge of evidence-based practice among clinicians. In addition, the current documentation system should be improved as soon as possible to facilitate the process of evaluating the clinical practice in future.


Mohamedraed ELSHAMI (Gaza, Israel), Enas ALALOUL, Reem DABBOUR, Mohammed ALKHATIB, Tamer ABDALGHAFOOR, Bettina BOTTCHER
08:30 - 17:40 #10871 - An evidence-based study: evaluating the management of sepsis and septic shock in the Gaza-Strip hospitals.
An evidence-based study: evaluating the management of sepsis and septic shock in the Gaza-Strip hospitals.

Background:

Sepsis and septic shock are major healthcare problems, affecting millions of people around the world each year. Since early identification and appropriate management in the initial hours after sepsis develops improves outcomes, adherence to clinical guidelines is very important.  This audit assesses the guideline adherence by physicians in the Gaza-Strip (GS) for management of sepsis and septic shock.

Methods:

This was a prospective clinical audit conducted in the medical departments of three of the GS hospitals from January to March 2017 according to surviving sepsis campaign (SSC) guidelines for management of sepsis and septic shock (2017).

Results:

In total, 70 cases were identified. The mean age was 75 ± 12 years and the mean duration of hospitalization was 7 ± 6 days.  Seventy percent were females and 88.6% of patients had co-morbidities with 19.4% having all of hypertension, diabetes and past stroke. It was noted that 25.7% had a breach of skin integrity as a risk factor for sepsis.
Starting intravenous (IV) antimicrobial therapy within the first hour was achieved in 89% of cases; however, requesting blood cultures was not done at all. In contrast, 4.3% had their blood cultures withdrawn within the first 3 hours and 28.6% received 30ml/kg crystalloid fluids. A specific anatomical diagnosis to control infection in the first 12 hours was made in 71.4%. Both of administering initial empiric therapy and daily reassessment of antimicrobial regimen were done in all cases. Combination empirical therapy was given to 72.9%. About 54% received therapy for longer than 10 days. Only 8.6% had selective oral decontamination using nystatin. Surprisingly, 18.6% did not receive crystalloids for resuscitation which were indicated. Only 2 cases (2.8%) had vasopressors, of which one was administered dopamine which should be avoided. Corticosteroids were administered in the absence of shock in 5.7%. A target of ≤ 180 mg/dL for blood glucose level was achieved in 72.9%, but before obtaining this target, its value was monitored every 4 hours only in 8.6%. Stress ulcer and deep vein thrombosis prophylaxis were given in 92.9% and 78.5%, respectively.

Discussion:

The results of this audit reflect the fact that the current practice for management of sepsis and septic shock doesn’t comply with the SSC guidelines. This could be explained by the lack of local guidelines and poor knowledge of international standards. Furthermore, the shortage of some laboratory tests (blood cultures and lactate level) may affect the clinical practice and the overall adherence to guidelines. Despite the fact that management of sepsis should be guided by lactate level, it was not done due to its unavailability in the GS hospitals. Therefore, there is an urgent need for developing local guidelines as well as promoting awareness and knowledge of evidence-based practice among clinicians and making key tests available to clinicians in the GS.


Enas ALALOUL (Gaza, Israel), Mohamedraed ELSHAMI, Esraa SALEH, Heba BARAKA, Alaa Eldeen ELMASSRY, Bettina BOTTCHER
08:30 - 17:40 #10466 - An hourly assessment of PaCO2 during the first twelve hours after ICU admission for all OHCA patients treated with TTM at 33°C is needed.
An hourly assessment of PaCO2 during the first twelve hours after ICU admission for all OHCA patients treated with TTM at 33°C is needed.

Introduction

Regardless of the recent advances in cardiopulmonary resuscitation and post-resuscitation care, most out-of-hospital cardiac arrest (OHCA) patients admitted to the Intensive Care Unit (ICU) decease due to post-anoxic neurological injury. Changes in carbon dioxide (CO2) increase the cerebral blood flow due to its vasodilating effect.

The aim of the study was to determine at what time interval the partial pressure of carbon dioxide in arterial blood (PaCO2) should be measured ideally in the post-resuscitation care setting in order to capture significant changes.

 

Methods

 

A prospective observational study was performed in 108 patients, successfully resuscitated from OHCA, and treated with Targeted Temperature Management (24 hours at 33°C, followed by 12 hours rewarming at 0.3°C/h). Following admission at the ICU, an hourly blood gas analysis was performed during the first 48 hours. Ventilation was adjusted to maintain mild hypocapnia (PaCO2 between 32 and 38 mmHg; pH stat approach). A delta PaCO2 was calculated with an interval of four hours (D4PaCO2) in order to capture significant differences in PaCO2 values over time. A Two-Way Anova with Bonferroni post-hoc analysis was performed to investigate whether the calculated delta PaCO2 values were different over time and between outcome groups. Outcome was assessed at 180 days post-CA using the Cerebral Performance Category (CPC) scale (CPC1-2: good neurological outcome and CPC3-5: poor neurological outcome).

 

Results

 

While 50 patients (46%) survived with a good neurological outcome at 180 days post-CA, 58 patients (54%) had a CPC score of 5. In total, twelve delta PaCO2 values were calculated over the first 48 hours after ICU admission. The calculated D4PaCO2 values were not different between patients with a good and poor neurological outcome (p=0.719). A significant time effect was present with respect to the calculated delta PaCO2 values (p<0.001). The first D4PaCO2 value (H5-H1) was significantly different from all subsequently calculated delta PaCO2 values (p<0.05), while the second D4PaCO2 value (H9-H5) was only significantly different from the first (H5-H1) and third D4PaCO2 value (H13-H9) (p=0.019 and p=0.047, respectively). No significant changes in delta PaCO2 values were measured twelve hours after ICU admission (p>0.05).

 

Conclusion

 

Our study suggests the need for an hourly assessment of PaCO2 during the first twelve hours after ICU admission for all OHCA patients treated with TTM at 33°C. Hereafter, a measurement of PaCO2 every four hours is sufficient to capture relevant changes in PaCO2 in hemodynamic stable patients.


Bart VAN DEN BROECK (Zonhoven, Belgium), Ward EERTMANS, Cornelia GENBRUGGE, Jo DENS, Cathy DE DEYNE
08:30 - 17:40 #10848 - An Infrequent Cause Of Abdominal Pain.
An Infrequent Cause Of Abdominal Pain.

A 31-year-old man was referred to the emergency room for acute abdominal pain and vomiting associated with psychomotor agitation.

He deny ingestion of alcohol or other toxins. Afebril at all times. No diarrhea, rectal bleeding or melena. No respiratory or urinary symptoms.

His relatives explain similar previous episodes in the last 6 months, all assessed and studied in the emergency room without an etiological diagnosis, and they añso denied any family epidemic environment.

On examination: afebrile and hemodynamically stable, agitated by pain, with soft abdomen, depressive, diffuse pain, abdominal noises present, no masses or megaly palpation, no pain in back renal zones.

Pain control with morphine is required.

Initial results =

1) ECG: sinus rhythm at 75lpm, heart axis at + 60º, PR <200ms constant, QRS <120ms correct morphology, no acute alterations of repolarization.

2) GSA (aa): pH 7.54 mmHg, pCO2 26mmHg, pO2 87mmHg, HCO3- 25.8mEq / l, lactic 1.87mmol / l, Na 135, K 3.1, Cl 104, Ca 4.75, glucose 151

3) Analytical: no leukocytosis. Hemoglobin, coagulation, renal function, ions, hepatic profile and amylase without notable alterations

4) Ethanol: negative

5) Urinary sample: no alterations

6) Toxics in urine: negative

7) Rx thorax: no condensations, no pleural effusion, no pneumothorax.

The results of initial tests were anodyne, likewise  the acute abdominal pain persist ... and the pacient explain previously similar episodes, it was decided to study urinary porphyria = 

porphobilinogen urgent for the diagnosis of porphyria crisis and abdominal CT scan. 

Abdominal-pelvic CT with contrast & complete abdominal ultrasonography (including renal): findings suggestive of enteritis secondary to intestinal infestation by parasites (to rule out Ascaris lumbricoides).

After assessing results of images with radiology equipment, the case is oriented as an enteritis secondary to intestinal infestation by parasites (to rule out Ascaris lumbricoides in stool samples, wich are taken for microbiology. Empirical treatment with Mebendazole.

 A. lumbricoides infects over 1 billion people; despite not being frequent in Europe, it has to be take into account when the most common causes have been discarded.


Julio OLSEN TRIULZI (Palma de Mallorca, Islas Baleares, Spain), German FERMIN GAMERO, Bernardino COMAS DIAZ, Beatriz RODRIGUEZ FISAC, Edwin PUERTO LARA, Pere RULL BERTRAN
08:30 - 17:40 #10456 - An uncommon case of severe cardiac glycoside toxicity: self-poisoning with Cerbera odollam.
An uncommon case of severe cardiac glycoside toxicity: self-poisoning with Cerbera odollam.

Self-poisoning with plant seeds or fruits is a common method of self-harm in South Asia and India, but uncommon in Europe. Cerbera odollam is a dicotyledonous angiosperm, a plant species in the Family Apocynaceae and known by a number of vernacular names depending on the region. The kernels of Cerbera odollam contain cerberin, a potent cardenolide glycoside belonging to the cardiac glycoside family of toxins that includes digoxin. We present the case of a 25-year-old man with a history of depression presented to the ED with abdominal pain accompanied by nausea and vomiting, blurred vision and diplopia. Upon further questioning in the ED, the patient admitted the intentional ingestion of two seeds of Cerbera odollam that he purchased from an online website. An electrocardiogram demonstrated first degree AV block, diffuse ST-segment depressions. He quickly became bradycardic and developed second degree AV block and afterwards third degree AV block. Repeated administration of digoxin immune Fab determined normalization of ECG abnormalities. The patient recovered was uneventfully and was later discharged in stable condition after 5 days in hospital. In conclusion, we report the first described case of cardiac glycoside toxicity in Romania due to self-poisoning with Cerbera odollam seeds. The ECGs for this case depicted the evolution of classic dysrhythmias, morphologic features, and electrolyte abnormalities associated with severe cardiac glycoside toxicity.


Vasile GAVRILA, Rodica Daniela GAVRILA, Gabriela FILIP, Diana NECHITA (, Romania), Adrian Cristian DOBRE
08:30 - 17:40 #10345 - An uncommon finding in head trauma: massive pneumocephalus with pneumorrhachis after severe skull base fracture.
An uncommon finding in head trauma: massive pneumocephalus with pneumorrhachis after severe skull base fracture.

Pneumocephalus is defined as an intracranial gas collection. Trauma is the most common cause of pneumocephalus (75-90%), but it may also be caused by infection, barotrauma following scuba diving and surgery involving the sinuses, orbit, nasal passages or intracranial space. We present the case of a 57-years-old man with severe head trauma, secondary to a road traffic accident, brought by ambulance in ED with altered mental status. On physical examination, the patient was agitated, confused, GCS of 7/15. An immediate brain computed tomography scan showed a basal skull fracture with massive pneumocephalus and pneumorrhachis, subdural hematoma without compressive effects. The patient was treated conservatively with a favorable outcome, complete neurologic recovery, without complications and was discharged after 11 days.


Vasile GAVRILA, Rodica Daniela GAVRILA, Gabriela FILIP, Alexandra Valentina STANCIUGELU (Timisoara, Romania)
08:30 - 17:40 #11650 - An unexpected finding in a trauma patient: a Grynfeltt-Lesshaft hernia.
An unexpected finding in a trauma patient: a Grynfeltt-Lesshaft hernia.

Background

Primary survey plays an essential role in the initial assessment of major trauma patients by identifying life-threatening injuries and initiating simultaneous resuscitation. Once completed, secondary survey can start along with radiological imaging as dictated by the primary examination findings.

 

Case

A 34-year-old female was brought in as a major trauma to our emergency department (ED) after being involved in a road traffic collision. She lost control of her car at 70 mph (113kmph), hitting the central reservation before squashing her car against a tree. She was wearing a seatbelt and the airbags were deployed.

On arrival to the ED, she was haemodynamically stable and her Glasgow coma score (GCS) was 12. The primary survey revealed facial and neck wounds, obvious deformity of the right wrist and swelling to the left knee.  A whole-body CT scan followed the primary survey and showed undisplaced fractures of the lateral aspect of the right 11th and 12th ribs, and a separation of the 9th and 10th ribs likely to be secondary to trauma. Through the separation there was a narrow necked hernia sac, containing the hepatic flexure, with the possibility of strangulation. This finding was in keeping with a Grynfeltt-Lesshaft hernia.

The patient underwent urgent surgical repair of the hernia and fixation of the ribs fractures.

 

Discussion

Abdominal hernias can be classified by location, content or aetiology. Our case would be regarded as a lumbar hernia which accounts for 2% of all reported abdominal hernias.

Anatomically the lumbar region is defined by the base of the 12th rib, the crest of the ilium, the external oblique muscle and erector spinae muscles. This area is then divided into the superior (Grynfeltt-Lesshaft) and inferior (Petit) triangles. The boundaries of the superior triangle are: lower border of the 12th rib, internal oblique and quadratus lumborum muscles. An inherent weakness is present in the superior triangle, compared to the inferior, due to the thin aponeurosis, and transiting nerves and vessels, within the floor. This makes hernias in the Grynfeltt-Lesshaft region more common than Petit’s hernias, although both are relatively rare.

In our case, it is a possibility the protective effect of the seatbelt might have contributed to the formation of this lumbar hernia by increasing the intra- abdominal pressure.

Complications of abdominal hernias include bowel obstruction, incarceration and strangulation. The risk of strangulation, and the tendency for these hernias to increase in size, makes surgical repair preferable to conservative management. The benefit of open versus laparoscopic repair remains contentious and the use use of mesh is a popular choice.

 

Conclusion

CT imaging is useful in the secondary survey and management planning of major trauma patients. It highlights pathologies with little physical signs, which are therefore hard to pick up on during the primary survey.


Sarah BAIRD, Abdo SATTOUT (Liverpool, UK, United Kingdom), James CHAMBERS, Mohamed ELMASRY, John TAYLOR
08:30 - 17:40 #11857 - An unusual case of DRESS (drug rash with eosinophilia and systemic symptoms) syndrome caused by colchicine.
An unusual case of DRESS (drug rash with eosinophilia and systemic symptoms) syndrome caused by colchicine.

INTRODUCTION:

DRESS (drug rash with eosinophilia and systemic symptoms) syndrome is characterized by rash, fevers, eosinophilia, lymphadenopathy, and systemic organ involvement. We report a case of DRESS syndrome caused by colchicine.

CASE REPORT:

A 67-year-old woman presented in April 2017 with an acute gout attack (first episode).  Colchicine was started .Two weeks after, the patient noticed diffuse itching, worsening from day to day. A generalized rash , face oedema and  fever appeared a few days later. Blood examination revealed moderate eosinophilia (7%) and hepatic failure (including cholestatic jaundice and cytolysis) , renal failure and metabolic acidosis. Additional investigations: Viral serologies were negative for cytomegalovirus, rubella, hepatitis B and C and  HIV . Thyroid function was normal. Abdominal echography and chest radiographs were normal.  All medications were stopped and  oral corticosteroid treatment was started. The  symptoms resolved and laboratory data normalized after 7 weeks. The diagnosis of drug rash with eosinophilia and systemic symptoms (DRESS) induced by colchicine was made.

CONCLUSION :

In conclusion, colchicine can be added to the list of drugs inducing DRESS syndrome. Pathogenesis is unknown, but may involve drug detoxifying pathways and accumulation of reactive metabolites.


Rim HAMAMI (Tunis, Tunisia), Ghofrane BEN JRAD, Dkhera HAMDI, Yosra GUETARI, Saloua MANSOURI, Ines GUERBOUJ, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11626 - An Unusual Case of Ethylene Glycol Poisoning.
An Unusual Case of Ethylene Glycol Poisoning.

Ethylene glycol is an alcohol found in many household products, odorless, colorless, and sweet in taste it is  frequently ingested by children, animals and in suicide purposes.

We present the case of an 57 old femele.  With a medical history significant for hypertension, diabetes  presented in the ED with slurred speech, dizziness, the lacking of coordination and nausea   On presentation, the patient was afebrile,GCS =15P,  BP=160/95, tachycardic, and tachypneic. Pulse oximetry showed a hemoglobin saturation of 98% on room air. Physical exam findings were normal except for nistagmus, dysarthria, Romberg+. The diagnosis seemed obvious - vertebrobasilar stroke.

 Her blood profile was normal, head CT was negative,  however, a point-of-care arterial blood gas revealed a Ph=7,25, Pco2=28, serum bicarbonate of 14mmoli/l, lactic acid=171mg/dl.

 The patient strongly deny any toxic ingestion, and we made a thorough investigation into the cause of this perceived severe lactic acidosis was undertaken and no clear etiology was identified. There was no evidence of sepsis (PCR=2,8 mg/L),. Furthermore, there were no signs of gangrenous tissue and surgical and radiological evaluations were negative for ischemic bowel or incarcerated hernia.

This was the moment when we returned to the patient and his family The patient and her family deny once again any ingestion of toxic substance. Then I sent her family home to bring us all the medications and syrups the patient had ingested in the last week. When they returned, they realized that ,accidentally, the patient consumed instead of pumpkin syrup – antifreeze.

During this time treatment was initiated, and after several fluid boluses and sodium bicarbonate administration, the acidosis and lactate levels  improve. The patient was admitted , with a favorable outcome, with renal function preserved. The patient was lucky to have ingested a small amount of antifreeze, and he quickly came to the hospital at the onset of the first symptoms.

The symptoms for which the patient came to the ER are very common, and we often have a tendency to jump quickly with a diagnosis, this case taught me that not everything is what it looks like and we must always go over all differential diagnostics, you never know when pumpkin syrup is actually antifreeze!


Dr Mates OANA (Targu Mures, Romania), Andreea STEFANUTI, Vicas DIANA
08:30 - 17:40 #10457 - An unusual case of obstructive jaundice: liver hydatid cyst.
An unusual case of obstructive jaundice: liver hydatid cyst.

Tapeworm Echinococcus granulosus is a common cause of hydatid disease, but the association between hydatid disease and jaundice is unusual. Obstructive jaundice associated with hydatid disease may occur in 3 ways: obstruction of bile ducts by intrahepatic cysts, rupture of cysts into the bile ducts, and extrinsic compression of bile ducts by a hydatid cyst. We present the case of a 49-years old female who presented to the emergency department with a five day history of jaundice and dark urine. Laboratory tests demonstrated bilirubinemia, and ultrasound showed a cystic image in the right hepatic lobe. Contrast-enhanced computed tomography (CECT), magnetic resonance imaging (MRI) and MR cholangiopancreatography (MRCP) showed a hydatid cyst in the right hepatic lobe without communication with the ducts. Therapeutic endoscopic retrograde cholangiopancreatography (ERCP) after MRCP confirmed the absence of hydatid material in the main bile duct and lack of communication with hydatid cyst. The patient was treated with albendazole, followed by surgical intervention. Postoperative evolution was favourable with no complications and the patient was discharged after 10 days.


Vasile GAVRILA, Rodica Daniela GAVRILA, Gabriela FILIP (Timisoara, Romania)
08:30 - 17:40 #9903 - An Unusual Case of Post- Traumatic Facial Nerve Palsy.
An Unusual Case of Post- Traumatic Facial Nerve Palsy.

An Unusual Case of Post- Traumatic Facial Nerve Palsy

Rana J H Hussein, MBBS, MRCEM, CABEM; Muhammed Ershad, MBBS, MRCEM

 

INTRODUCTION

Trauma accounts for 19% of facial nerve palsy in children. It is more common in girls than boys. Children from 2 to 8 years are most effected.

We report an unusual case of unilateral facial nerve palsy in a child after minor head trauma.

CASE REPORT

2 year old female child presented by her mother for mouth deviation after a fall, one day ago. The child slipped and hit her forehead on the floor. There was no loss of conscious, no vomiting, and no seizures. But the mother noticed the child’s mouth deviated to the right, after one hour of the fall.She had no flu or ear pain . No past history of diseases. Examination: patient was conscious, playful. CNS exam showed inability to close the right eye ,mouth deviated to the right, no wrinkles on the right forehead, localized small swelling, bruise on the forehead. No signs of basal skull fracture,systemic  examination was normal.

CT head reported no skull bone fractures, but a small subgleal hematoma was noted in the frontal region.

The pediatric and ENT surgeons, advised discharge with lubricant eye drops, only. After six weeks, the child was followed up in the clinic.The facial nerve palsy totally resolved.

DISCUSSION

Post-traumatic facial nerve palsy is evident with direct trauma to the ear, or head injury. Usually there is basal or temporal bone fracture. The pathophysiology of facial nerve palsy is either direct laceration to the nerve or edema of the facial nerve due to compression.Within 3 months, 90% of cases resolve with steroids

CONCLUSION

Post traumatic facial nerve palsy can happen in children with no skull bone fractures and can be managed conservatively, without the use of steroids.Spontaneous resolution  can be within six weeks. In pediatrics, consider non accidental injuries , in post traumatic facial nerve injury.

 

REFERENCES:

1-www.uptodate.com

2-Head injury with sudden onset bilateral facial palsy-can happen without temporal bone fracture and brain injury. Egyptian journal of ENT and allied sciences. Vol 17, issue march 2016

Santosh Kumar sawan, Ishwar Chandra behera, Mahesh Chandra Sahu

3- Post traumatic bilateral facial nerve paralysis associated with temporal bone fracture. J Coll Physicians Surg Pak 2015 Suppl 2: S132-3. Doi: 10 2015/JCPSP. S132133

Habib SS,Al Rouq F,Meo I

4- Clinical features of outcomes of delayed facial palsy after head trauma. Auris Nasus Larynx. 2016 Oct, 43(5). 514-7. Doi: 10. 2016/j.anl 2015.12.017.Epub 2016 Feb 1.

Li Q,Jia Y, Feng Q, Tang B,Wei N, Zhang Y, Li Y , Zhang X

5-Facial nerve palsy after head injury: case incidence, causes, clinical profile and outcome.

Department of neurosurgery, college of Medicine, university of Ilorin, PMB1515, Nigeria

Jtrauma 2006, August 61(2):388-91


Rana HUSSEIN (Qatar, Qatar), Muhammed ERSHAD
08:30 - 17:40 #11475 - An unusual case of Salmonella Enteritidis causing septic shock and multiple organ failure:.
An unusual case of Salmonella Enteritidis causing septic shock and multiple organ failure:.

Introduction:

Salmonella species are facultative intracellular pathogens that most frequently cause self-limiting gastrointestinal disease, often acquired through the ingestion of contaminated food. Gastro-enteritis is the main clinical aspect of salmonellosis which is becoming more frequent. Extra-digestive manifestations, less frequent, affecting usually patients at risk, must be recognized. Different localizations of infection are possible. Some can be severe and fatal. The possibility of salmonella sepsis must be considered when immunodepressed patients have fever and no obvious source of infection.

Case Report :

We reported the case of a patient aged 45 years old. She had a charged medical history, in fact, she is diabetic and she is treated for Takayaschu pathology by Methotrexate and corticoid. She was hospitalized for gastroenteritis salmonella four months ago, also another time one month ago for urine infection from salmonella treated with intravenous antibiotic. She returns for fever.

On physical examination revealed patient with fever: 38, 5. She was conscious, glycemia was correct, her blood pressure was normal. The abdominal examination revealed lower right quadrant tenderness.

Biological test show: normal glycemia, renal failure with clearance of creatinine at 20 ml/min. CRP level was 235 mg/dl. Urine culture and blood culture was positive in salmonella enteritidis .She was immediately given Ceftazidime.

12 hours later, the patient developed a septic shock .She become confused, with an hypotension, anuria and respiratory distress. She required an endotracheal intubation and mechanical ventilation and she was charged to the intensive care unit. Multiorgan failure occurred rapidly leading to death in 24 hours.

 Conclusion :

Salmonella can produce bacteremia and disseminated disease. The sever form can be fatal especially in immunodepressed patients.

 


Houda NASRI, Rim HAMAMI (Tunis, Tunisia), Olfa DJEBBI, Dkhera HAMDI, Yosra GUETARI, Bassem CHATBRI, Khaled LAMINE
08:30 - 17:40 #11159 - An unusual cause of right upper quadrant pain.
An unusual cause of right upper quadrant pain.

Case Report

A 38-year-old male presented to our emergency department (ED) with sudden onset of intermittent abdominal pain in the right upper quadrant. Besides obesity (BMI of 34), he had no previous medical history. His vital signs were a heart rate of 120 per minute, blood pressure of 154/77 mmHg and temperature of 36.7°C. Physical examination revealed right upper quadrant pain on palpation with rebound tenderness and positive Murphy’s sign. Laboratory findings showed mildly elevated inflammatory parameters with C-reactive protein of 70 mg/L (normal range <3 mg/L) and white blood cell count of 11.6 x109/L (normal range 4.3-10.0 x 109/L). Ultrasound of the abdomen revealed a normal gallbladder without signs of cholecystitis. The tentative diagnosis of cholecystitis remained and the patient was admitted for observation. He was discharged the next day because of spontaneous resolution of the symptoms. One day later he represented to our ED with similar symptoms. A computed tomography (CT) of the abdomen was performed and revealed an omental infarction. The patient was treated conservatively and made a full recovery. He was discharged three days later.

Discussion

Omental infarction is a rare cause of acute abdominal pain, mimicking acute appendicitis, cholecystitis and other intra-abdominal emergencies. The clinical presentation is atypical, with a subacute onset of severe abdominal pain and signs of peritonitis. Approximately 400 cases have been reported, of which 85% in adults, most frequently in the age group of 40-50 years and twice more common in males. Leitner et al. classified omental infarction into primary and secondary types. Secondary infarction can be induced by omental torsion, thrombosis due to hypercoagulopathy or vascular malformations. When no clear etiology is found, omental infarction is called primary or idiopathic and these cases may be related to obesity and local trauma.

Diagnosis can be established by CT scan. Usually, a large triangular or oval-shaped encapsulated fatty mass interspersed with areas of hyperattenuating streaky infiltration is found. These findings are virtually pathognomonic for omental infarction. Yet a significant number of patients are still diagnosed intra-operatively. Ultrasound is less useful as it may not distinguish infarcted fatty lesions from normal intra-abdominal fat.

Because of the self-limiting course of this disease, conservative treatment with analgesics and anti-inflammatory drugs is recommended. However, persistent pain and complications such as intestinal obstruction and abscess formation have been reported. In these cases, surgical treatment may be required.

Conclusion

Omental infarction is easily mistaken and should be considered in the differential diagnosis of acute abdomen. CT scan of the abdomen confirms the diagnosis. The typical course is self-limiting and therefore a conservative approach is recommended. In cases of persistent pain or progressive peritonitis, surgery may be required.


Jasper VANHOVE (Edegem, Belgium), Hannelore RAEMEN, Griet VERMEULEN, Annemie SNOECKX, Koen MONSIEURS
08:30 - 17:40 #10935 - An unusual presentation of miliary tuberculosis: case report.
An unusual presentation of miliary tuberculosis: case report.

Miliary tuberculosis (TB) is a potentially lethal disease if misdiagnosed or left untreated. We present a case of a 58-year-old man complaining of left arm pain and swelling, coughing, dyspnoea and malaise. His past medical history included left arm trauma two years prior. The patient was abusing alcohol. On admission the patient was pale and cachexic with a blood pressure of 110/60 mmHg. Auscultation of the lungs was not conclusive; some fine crackles were audible bilateraly. Physical examination revealed left upper arm deformity and swelling of the soft tissue, tenderness on palpitation, lack of movement in left shoulder and elbow, bilateral leg weakness. Laboratory tests revealed a slightly elevated white blood count,  decreased hemoglobin of 81 g/l, CRP of 212,6 mg/l, slightly elevated ionized Calcium level of 1,64 mmol/l. Plain radiograph of the left shoulder showed bone destruction of proximal humerus. The chest radiograph showed a bilateral micronodular interstitial pattern indicative of miliary tuberculosis and left pleural effusion. Left upper arm ultrasound showed subcutaneous edema and small fluid collections about 15 mm. On the basis of clinical presentation, laboratory test results and radiographic findings the diagnosis of military tuberculosis with dissemination to the bones was made. TB should be kept in mind when differentiating the cause of bone lessions. 


Renata ANDROSAITE (Vilnius, Lithuania), Vilma VAPSVAITE, Raliene KAROLINA
08:30 - 17:40 #11128 - Analgesia and anesthesia of patients with injuries of HIP in ER.
Analgesia and anesthesia of patients with injuries of HIP in ER.

  • Objectives : For the past 5 years in a ward of the University Hospital in Pleven passed 40 135 patients with various injuries .From these fractures of the hip are 6.9% and of them specifically the femoral neck - 13.5% .These patients are mainly adults over 70 age with multiple comorbidities and higher risk of complications with standard analgesia with intravenous opioids. This study aims to compare the standard pain management with opiates or NSAIDs with regional nerve block made in a compartment under ultrasound guidance.
  • Study selection: Randomized trial including adult patients with a hip or femoral neck fracture  who had a 3-in-1 femoral nerve block, traditional femoral nerve block and traditional pain menagment with opioids or NASIDs.
  • Conclusions: Regional nerve blocks for hip and femoral neck fractures reducing pain and the need for IV opiates. We recommend using these units for management of pain in emergency rooms as a safe and relatively easy for  these patients. 

Petko STEFANOVSKI (Pleven, Bulgaria, Bulgaria), Vladimir RADEV, Lyubomir TSANKOV, Slavejko BOGDANOV, Radko RADEV
08:30 - 17:40 #11265 - Analysis of calls for unconsciousness in the call reception and control center.
Analysis of calls for unconsciousness in the call reception and control center.

Introduction: the aim of this study was to analyze calls for unconsciousness in the call reception and control center (CRCC) and in particular to identify the proportion of patients really unconscious

Methods: this was a prospective, observational study using the MECU-database for calls about unconsciousness, during one month. Were considered unconscious at the arrival of SMUR teams, patients with GCS<9 or those descibed as such. We studied the demographic characteristics of patients and the evaluation of conscious by the regulator physician and by the SMUR physician. The results were expressed an mean±SD and percentage.

Results: Ninety six patients were included. The sex ratio was 0.8. The mean age was 50±22 years. The phone evaluation by the ragulator physician, was identified 36% unconsciousness, 30% were aware and there was a doubt for the state of conscious in 34% of cases. The intervention team was engaged in 81% of cases. At the arrival of the SMUR team, 27% of patients were unconsciuous, 49% were aware and 22% had a brief knowledge loss.

Conclusion: Among the calls for unconscious subject, one patient in two was conscious at the time of the call, and that two patients out ot three are conscious at the arrival of the SMUR teams. These results hihlight the difficulty of medical regulation for the calls.


Wided BAHRIA (tunisie, Tunisia), Saida ZELFANI, Syrine KESKES, Hela MANAI, Mylène BEN HAMIDA, Wafa LIMAM, Mounir DAGHFOUS
08:30 - 17:40 #10902 - Analysis of emergency department visits by elderly patients in a Croatian clinical hospital.
Analysis of emergency department visits by elderly patients in a Croatian clinical hospital.

Background: Aging of the population and changing global demography is resulting in older people presenting to emergency departments (EDs) more frequently. Such patients admitted to hospital as medical emergencies are a more heterogeneous population than younger population, often present with atypical sign and symptoms that complicate diagnosis and treatment. The aim of this study is to describe the trend in ED visits by patients aged 85 years and over between 2010 and 2016 encompassing reasons for attendance.

Methods: Data considered were all ED visits to the Clinical hospital Sveti Duh, Croatian teaching hospital, between 2010 and 2016 by patients aged 85 years and over. Demographic characteristic, incidence rate of ED, reasons for visit, length of ED stay and factors such as day of week, and season were analyzed retrospectively.  For the purpose of analyses, patients were classified into three groups related to the clinical symptomatology: internal medicine, surgical and neurological patients.

Results: We analyzed 18,892 visits by patients aged over 85, accounting for 5,3% of the total ED visits for the study period (2010 -2016). Most of them were female (69,6%). Overall ED visit for patients over 85 years increased from 1948 visits in 2010 (4,2%) to 3362 (6,9%) in 2016.  The season in which emergency visits are the most frequent was winter and Mondays saw the highest number of ED visits over the study period (2935 visits). The number of visits decreased as the week continued and weekend days, Sundays and Saturday had the lowest number of ED visits (2169, 2262 visits, respectively). The most common chief complaints and ED diagnoses were cardiovascular (31,6%), trauma (20,4%), neurological (15,3%), pulmonary (8,7%), gastrointestinal (8,5%) and  disease of the skin and subcutaneous tissue (3,5% ).

Conclusion: The proportion of emergency department (ED) attendance of elderly people over the age of 85 increased during the study period. The most common diagnosis was disorder of the cardiovascular system.


Pr Višnja NESEK ADAM (ZAGREB, Croatia), Ivan JURIĆ, Ingrid BOŠAN KILIBARDA, Ingrid PRKAČIN, Damir VAŽANIĆ
08:30 - 17:40 #11737 - ANALYSIS OF THE ANDALUSIAN EMERGENCY PLAN BY MEANS OF THE SIMULATION OF AN AIRCRAFT ACCIDENT AT THE AIRPORT OF SEVILLE.
ANALYSIS OF THE ANDALUSIAN EMERGENCY PLAN BY MEANS OF THE SIMULATION OF AN AIRCRAFT ACCIDENT AT THE AIRPORT OF SEVILLE.

INTRODUCTION:

 

A simulation of an aircraft accident was performed in 2017 to analyze the Multi-Victim Care Plan (MVCP) in the Virgen del Rocio University Hospital, a .3rd level Hospital of Seville (Spain). This Plan was analyzed to measure our assistance response and detect deficits to be corrected.

 

OBJECTIVES:

Check the operation of the emergency plans, the effectiveness and coordination of the personnel involved in a real accident. Evaluate the Hospital's MVCP protocols to improve the services and resources involved in a real accident and  to verify the coordination between the different participants.

 

MATERIAL AND METHODS:

The simulation consisted in an aircraft accident which occurred during the landing maneuvers of a 19-passenger plane. The plane burned because of fuel spills, four of passengers died, three were unharmed and another 12 were injured. They were transferred to the emergency service of our Hospital by the out-of-hospital emergency team.

 

- It was activated the Emergency Services of different Units like Traumatology , Intensive Care, Rehabilitation, Plastic Surgery, Maxillofacial Surgery, Traumatology, General Surgery, among others.

-The family waiting room was included as a care area and the emergency capacity of the emergency area was doubled in both health personnel and care material for the care of Critical patients.

-Every person external to our emergency department was evacuated to the other areas.

-Multidisciplinary emergency care teams were created to care different types of patients.

 

RESULTS

 

Alert phase: lasting 19 minutes. Incidence: the alert call of out-of-hospital emergency team did not enter by communication channel  planned.

Alarm activation phase: the call center did not have an updated staff list for the cascade of incoming calls.

Evacuation of victims: lasting 45 minutes

 

Number of victims 12 (7 with red label 7 patients with a Revised Trauma Score (RTS) less or equal to 10 and 5 with green labels (2 of them converted to yellow and 1 to red) Patients destination: ICU: 4, Operating room and ICU: 3; General admission: 3; External consultations 2.

 

Number of real patients attended during the simulation: 25,

Training time for the multidisciplinary teams: 5-8 minutes

We found out that the care coordinator cannot be the leader of the emergency room which performs the prioritization of complementary tests and surgery planning of the critical patients due to the excess of assigned tasks

Ambulances for the transportation of mild patients waiting for getting the medical equipment needed blocked the access to the Hospital

 

 

CONCLUSIONS:

1- The activation and implementation of MVCP was correct and adequate.

2 - The capacity for simultaneous clinical care of 6 critical patients has been confirmed (patients with Revised Trauma Score (RTS) less or equal to 10)

3 - Improvements and modifications of the MVCP were detected in the phase of alert, alarm, evacuation and reception.


Pilar CONDE (SEVILLA, Spain), Jesus MORENO, Alberto MORENO, Maria PEREZ, Ignacio PEREZ-TORREZ
08:30 - 17:40 #11892 - Analysis of the clinical profile of patients diagnosed with atrial fibrillation at the Emergency Department.
Analysis of the clinical profile of patients diagnosed with atrial fibrillation at the Emergency Department.

Introduction:

Atrial fibrillation (AF) is the most frequent arrhythmia in clinical practice and implies an increase in mortality. The ischemic stroke is the most serious complication. It is important to know the factors that favor its appearance and development. An appropriate treatment can reduce the likelihood of new recurrences of AF or prevent it becoming permanent.

Objective:

To know the clinical profile of patients diagnosed with AF in the Emergency Department.

Material or patients and method:

Observational, retrospective study developed at the General University Hospital Reina Sofía. We included 761 patients diagnosed with AF attended between October 2012 and December 2013. The clinical profile of these patients is analyzed.

Results:

We evaluated 761 patients with AF. The mean age of these patients was 72.3 ± 13.3 years. Of these patients, 490 (64.4%) were women and 271 (35.6%) were men. Regarding clinical characteristics, 566 patients (74.4%) had hypertension (HTA), 204 (26.8%) diabetes mellitus (DM), 311 (40.9%) dyslipidemia (DLP), 16 (2.1%) hyperthyroidism, 100 (13.1%) bronchopathy, 75 (9.9%) chronic kidney disease, 85 (11.2%) previous stroke, 17 (2.2%) peripheral embolism, 106 13.9%), heart failure, 79 (10.4%)  anemia. In addition, 58 (7.6%) of the patients were smokers, 20 (2.6%) chronic alcohol users, and 7 (0.9%) consumed drugs. The mean score of the HAS-BLED scale of our patients was 3.4 ± 1.9 and of CHA2DS2-VASc 2.2 ± 1.4.

Conclusion:

After the study of the clinical characteristics of patients with AF attended at the Emergency Department, we found that this arrhythmia is more frequent in patients older than 70 years and in women. In addition, all patients have a high rate of cardiovascular risk factors.  The most frequent risk factor was hypertension.


Danae FERNANDEZ-CAMACHO, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Blanca DE LA VILLA ZAMORA, Pascual PIÑERA SALMERÓN (montepinar, Spain), Blanca MEDINA TOVAR
08:30 - 17:40 #11553 - Analysis of the emergency prescription and the patient's compliance to physiotherapy rehabilitation of the ankle's collateral ligament sprain.
Analysis of the emergency prescription and the patient's compliance to physiotherapy rehabilitation of the ankle's collateral ligament sprain.

Aim and methods :

A monocentric, prospective, qualitative and quantitative study was carried out in an emergency department. The main criterias were the analysis of prescribing, patient's compliance, and the efficiency of physiotherapy rehabilitation in ankle's collateral ligament sprains.

Results :

142 patients were included, 43% of whom were women. 53.6% with a sprain recurrence, of which 67% occurred on the same ankle. The RICE protocol was applied in 100% of cases, but only 60.5% of patients had a physiotherapy prescription, and 54% believed that they had an explanation about the aim of rehabilitation. Patients who received an explanation were 12% more likely to visit the physiotherapist than those who did not.

In total, 71% of patients with a prescription had physiotherapy. However, 28.5% of patients who did not receive a prescription benefited from physiotherapy through the secondary intervention of their general practitionner. 76.3% of patients began rehabilitation within 2 weeks of the trauma, 32.7% within 5 days. Rehabilitation is judged efficient in this study if exercises of mobility gain and stability as well as muscular reprogramming techniques are performed, with at least 3 of the following 5 criterias performed: proprioceptive massage / unipodal and bipodal exercises / discharge and weight-bearing exercices. 78.7% of the medical treatment brought by physiotherapists met these criterias. Ultrasound and external electrical stimulation, which are discouraged, but were carried out in 36.5% and 27.3% of cases, respectively. The average number of sessions is 10, with 2 to 3 sessions per week.

Discussion :

Lack of information on the need for rehabilitation as early as possible, influencing the number of patients with follow-up and rehabilitation. However, encouraging results with a high rate of compliance and effective rehabilitation.

Conclusion :

Need for standardization of practices, updating of knowledge on the latest recommendations, generalization of physiotherapy prescriptions with a clear explanation for the patient's compliance to the care project, and didactic information tools.

There could be an advantage to interdisciplinarity with physiotherapists in order to know their rehabilitation techniques and methods to reduce recurrences and complications in the medium and long term.


Jean-Rémy SAVINEAU (Colmar), Hélène STAHL, Mélanie JACQUET, Sophie PINCEMAILLE, Anne-Charlotte MAISONNEUVE
08:30 - 17:40 #10934 - Analysis of the Medical Care Performed in a Pre- Hospital Emergency Unit- Ribeirão Preto- Brazil.
Analysis of the Medical Care Performed in a Pre- Hospital Emergency Unit- Ribeirão Preto- Brazil.

Brazil has a Unified Health System to serve the population. Its scope ranges from simple ambulatory care to organ transplantation, thus ensure universal, free and universal access for all country population.

The services in the Unified Health System are divided according to their severity in: basic care, intermediate level and medium and high complexity.

Basic care services are provided in the Primary Care Service Unit and by Family Health. Those at the intermediate level are performed by the Mobile Emergency Service (Mobile Pre-hospital Care) and the Municipal Emergency Care Units (pre-hospital fixed care). The medium and high complexity services are performed in tertiary referral hospitals accredited to the public network.

The Municipal Emergency Care Unit is qualified to care for any type of medical emergency, traumatic or non-traumatic. It has offices of medical clinic, pediatrics, dentistry, radiology service, laboratory and observation beds are available. Patients are seen attendance according to the Manchester protocol.

In Ribeirão Preto, the Municipal Emergency Care Unit was inaugurated in June of 2013 and became a reference for the care of all city population (674,405 inhabitants), due to the quality of care offered.

The University of Ribeirão Preto has an agreement with the city hall, so that this Unit can be used as a clerkship for medical students.

In 2016, 228,294 attendance were made to this Unit. The majority of these services are of low complexity, but the care for medium and high complexity levels has been increasingly over the last years.

Methodology: We performed a retrospective study of patients who were treated at this unit and who needed hospitalization to complement their treatment. We analyzed the following variables:  pathologies, sex, age. With these data, it was possible to trace an epidemiological profile of the main pathologies that affect the population and to draw action plans so that the medical attention has been improved. Statistical analysis: multivariate analysis.  

Results: Most of the cases requiring hospitalization were basically due to three general causes: pneumonia, ischemic heart disease and stroke.

Conclusion: The Ribeirão Preto's Emergency Care Unit was useful for the initial approach of clinical and surgical emergency cases. The integration of Units with other health services is crucial for the proper medical care of emergencies.


Rosemary DANIEL, Matheus FERREIRA (Ribeirao Preto, Brazil), Santos LUIS, Danilo CASTRO, Vanderlei PALOCCI, Lelio PINTO, Melissa CESARIO, Rodrigo BRIGATO, Tufik GELEILETE, Reinaldo BESTETTI
08:30 - 17:40 #11226 - Analyze of procedure indicators in the accidents with multiple victims in urban area.
Analyze of procedure indicators in the accidents with multiple victims in urban area.

Introduction: the aim of our study was to determine the epidemiological profile of accidents with multiple victims during the year 2016 and pick up the dysfunctions of organization of intervention and the victim's management

Methods: it was a prospective study that deals with mass casualty accidents managed by the SMUR teams during the year 2016. Data have been provided by the regulation notes. We define a multiple victim's accident as an accident leading to five victims or more. We have established an adapted a simplified procedure of alert and response that is carried out in case of multiple casualities accident. Procedure dysfunctions are systematically analyzed after each accident.

Results: we have managed 26 accdents with multiple victims between January the first and December the 31 st 2016. The total number of victims was 284 (average: 10,92 per accident) and 11 deaths recorded on the scene of accidents. After the analysis of the data related to these interventions, the quality committee identified the following dysfunctions: delayed alert from fire-man operating center. Absence of a referent physician or specific phone number in the emergency services in order to receive the first call from the regulation center. That results in delayed information of an imminent massive affluence of many victims to the emergency services. Delayed access to the accident scene by the SMUR teams because of the road traffic

Conclusion: to correct all these dysfunctions, we elaborated an immediate alert system involving paramedics and radio communication means with emergency services.


Wided BAHRIA (tunisie, Tunisia), Saida ZELFANI, Hela MANAI, Syrine KESKES, Rafika BEN CHIHAOUI, Slim BEN DLALA, Mounir DAGHFOUS
08:30 - 17:40 #11873 - Ankle sprain and ... something else?
Ankle sprain and ... something else?

We present a case of a 79 years- old patient, with a medical history of high blood pressure and atrial flutter and surgical history of dupuytren illness. In treatment with Proton pump inhibitors, angiotensin enzyme converting inhibitors, acenocumarin and flecainide.. No allergies. He was attended at the Emergency Department reporting pain after having twisted the left ankle and he was not able to put weight on the foot. At first, it seemed to be a severe ankle sprain. Physical examination revealed a haemodynamics stability of patient, but he referred intensive pain, which precluded ambulation.  In the left foot, both malleolus had swelled up and were painful, specially tibial intern malleolus area where we felt a gap. He also presented pain in deltoid ligament, in the collateral ligament and mild pain in the head of fibula. Achilles tendon was not damaged . Rest of tarsus relief were not painful. Flexion and extension were preserved actively. There were neither distal neurovascular disorders nor distal trophism disorders.

The radiological study revealed an internal malleolus fracture , and a fracture of the fibula´s head. It was treated with orthopedic surgery successfully.

Discussion:  

Maisonneuve fractures are rare ankle injuries, they represent up to 7% of all ankle fractures. They consist on a proximal third fibula fracture, syndesmotic disruption, and medial ankle injury (either a deltoid ligament disruption or a medial malleolus fracture. Most patients refer significant ankle pain but very little pain over the fracture. The clinical examination and radiological studies are usually directed to the ankle region; and the proximal fibula is often ignored so, the clinical assessment should consist on a comprehensive history including mechanism of injury followed by a specific physical examination.


Isabel PEREZ, Teresa ESCOLAR (ZARAGOZA, Spain), Paula MUNIESA, Maria PERALTA, Alberto DIEZ, Nestor GRAN
08:30 - 17:40 #11362 - Anterior Shoulder Re-location Using Intra-articular Lidocaine-Possible Alternative to Conventional Sedation.
Anterior Shoulder Re-location Using Intra-articular Lidocaine-Possible Alternative to Conventional Sedation.

INTRODUCTION

A 25-year-old male presented to the emergency department with a right shoulder dislocation post fall while playing rugby. 

On examination, contour of the right shoulder was lost, arm abducted and externally rotated with normal neuro-vascular examination. Clinically looks anterior shoulder dislocation, confirmed by Ultrasound and X-ray (no fracture).  Previously 6 months ago, Same Shoulder was tried to reduce using entonox, and other techniques, upon failure, then reduced under full sedation, extending his stay more than 4 hours in ED.

 

TREATMENT

Patient was given different options for shoulder relocation, and after full informed consent from patient, ultrasound guided right shoulder intra-articular injection of 2% 10ml, Lidocaine was given, using full aseptic conditions. Patient shoulder was successfully reduced after 10 minutes of Lidocaine injection using Modified Kocher's technique. Post reduction neurovascular examination was normal with no complications of the procedure. Reduction was confirmed by Ultra-sound as well as by the X-ray. Patient was very comfortable and pain free until he left the emergency department in broad arm sling in 45minutes after the procedure

Patient discharged to fracture clinic with closed follow up of patient was done at 3rd day, 2 weeks and then at 3 months , no complications were reported by patient, post IAL injection.

DICUSSION

Shoulder joints accounts for 50 % of all major joint dislocations (1). Emergency physician role is to diagnose type of dislocation 2-, manage by reducing with suitable technique.

Shoulder dislocation is common presentation to the emergency department. Intra-articular lidocaine injection in adult patients is not common method to reduce dislocated shoulder. It can be an alternative to reduce shoulder dislocation as compared to sedation with or without analgesia, in the busy emergency department and, with fewer complications and side effects3, 4,5 . Whereas sedation has more complications or limitations.                                                   

With its benefits, more work needs to be done to adopt this as possible alternative to conventional sedation.

 


Muhammad Zeeshan AZHAR (Barrow in Furness, United Kingdom), Kiren GOVENDER
08:30 - 17:40 #11126 - Antiarrhythmics and pregnancy: Which is the best option in supraventricular tachyarrhythmia?
Antiarrhythmics and pregnancy: Which is the best option in supraventricular tachyarrhythmia?

BACKROUND

Cardiac arrhythmias are among the most common cardiac complications during pregnancy. This is likely due to a combination of hemodynamic, hormonal and autonomic changes. These changes include a 30-50% increase in cardiac output until 34 weeks, with heart rate rising at 20 weeks, and increases until 32 weeks; and stradiol and progesterone have been shown to be proarrythmics. Acute supraventricular arrhythmia in pregnancy is a problem because it impairs maternal and fetal blood circulation. However, severe arrhythmias that need aggressive treatment are unusual. We present a clinical case on the management of a pregnant woman with supraventricular tachycardia.

CLINICAL CASE

A 38-year-old pregnant woman was admitted to the emergency department with uterine dynamics. She was 29 weeks twin pregnant and obstetricians started fetal lung maturity and tocolysis.  During admission, she referred sudden onset of chest palpitations, commenting that she usually had these. Maternal and fetal monitoring was initiated. Physical examination revealed a heart rate of 195 bpm, a blood pressure 97/62 mmHg and an oxygen saturation of 99%. Twelve-lead ECG showed narrow-QRS complex tachycardia. We contacted with the cardiology team, agreeing to perform vagal stimuli as first-line treatment, with adenosine as second-line if this were not enough. Carotid sinus massage and Valsalva maneuvers failed, thus pharmacological cardioversion was succesfully performed with 3mg of intravenous adenosine, converting the tachycardia in normal sinus rhythm. Cardiotocographic monitoring did not show any effect of adenosine on any fetal heart rate during the drug administration and the following 30 minutes. Tocolysis was reinitiated and uterine dynamics stopped. The patient was discharged after four days hospitalization. Catheter ablation was suggested but the patient refused.

 

DISCUSSION

Symptomatic exacerbation of paroxysmal supraventricular tachycardia occurs during pregnancy in 20-44% of cases. Even though most palpitations are benign, patients should be investigated for the presence of structural heart disease.

Therapeutic approach to arrythmias in pregnancy is similar to that in non-pregnant patients. Most of antiarrhythmics are considered by the Food and Drugs Administration (FDA) as category C, meaning that risk to the fetus cannot be ruled out.  They have the maximal teratogenic risk on the first trimester and they should be used at theirlowest effective dose.

Adenosine has been used safely in pregnant women without significant adverse effects. Electric cardioversion is a reasonable option at all stages of pregnancy when arrhythmias are associated with hemodynamic instability. Cardioversion does not compromise blood flow to the fetus.


Mireia CHANZA (BARCELONA, Spain), Marta MAGALDI, Angel CABALLERO, Antonio LOPEZ, Jose Maria GOMEZ, Jaume FONTANALS
08:30 - 17:40 #11596 - Antibiotic Prophylaxis for Chest Drain Insertion in the context of Trauma.
Antibiotic Prophylaxis for Chest Drain Insertion in the context of Trauma.

Background/ Aim

Closed tube thoracostomy (TT) insertion for trauma patients is associated with an infectious complication rate for empyema, pneumonia and wound infection of 5.8-13%. The British Thoracic Guidelines (BTS) recommend prophylactic antibiotic use. However, implementation of this recommendation is variable.

Standard

BTS advises that antibiotic prophylaxis should be considered at TT insertion in the context of trauma.

Methods

A retrospective case review of all patients who received a TT in UHNM Emergency Department, over the 18 month period from April 2013 and September 2014 was conducted. In total, 84 patients (23 female, 61 male) with an average age of 47.9 years and ISS score of 20.1 were identified from data submitted by UHNM for TARN audit purposes. Their medical notes were requested and used for data collection.

Results

A ratio of 1:7.4 for penetrating vs bunt injury was found. In total, 22/84 patients (28.6%) developed an infectious complication attributable to TT. Of these, 12 had not received prophylactic antibiotics. Overall, the likelihood of acquisition of an infectious complication when given prophylactic antibiotics was associated with an odds ratio of 0.225 (CI 0.079-0.631) and a NNT of 3. Thus, support for the use of antibiotic prophylaxis for TT in the context of trauma was found, in concordance with BTS guidance.

Conclusion

As supporting evidence was found, guidance was produced, advocating prophylactic use of Co-Amoxiclav for patients requiring TT insertion due to trauma. This is currently, being proposed for inclusion in UHNM’s Emergency Medicine guidelines.


Sophie BURNAGE (Stoke-On-Trent, United Kingdom), Ruth KINSTON
08:30 - 17:40 #11272 - Anticholinergic Syndrome After Ingestion Of Lupine Water.
Anticholinergic Syndrome After Ingestion Of Lupine Water.

Background:

Anticholinergic syndrome is widely described after ingestion of some drugs or plants. Inadequate debittering of Lupine beans can also cause this syndrome. However, there are few case reports in the literature; we describe a case of rare lupine toxicity with  significant clinical findings.

History:

A 65 years old male, with DM on metformin, HTN on Amlodipine , cholecystectomy and prostatic hypertrophy on Tamsulosin, presented to Emergency Room.

He gave a history of 2 hours of dizziness, dry mouth, urinary retention, constipation, abdominal pain with distention  and blurred vision, after ingestion of about 200 ml of water used to debitter lupine or Turmus seeds. He drank it to try to improve control of his blood sugar.He had no history of fever.

Examination:

He looked with no flushing and was apyrexial (36.4º C). He had dry skin and oral mucosa. His pulse rate was 102 bpm, blood pressure 148/89 mmHG, respiratory rate 19/min, and 100% oxygen saturation in room air.

He was noted to have abdominal distension.

He was fully conscious and orientated; he had bilateral mydriasis but no other cranial signs and normal power, sensation, reflexes and co-ordination.

Abdominal XR showed bowel distention and air-fluid multiple levels.
CT Abdomen showed diffuse dilatation of the mid and distal small bowel loops, extending up to the ileocecal junction, indicating small bowel obstruction.                  

His WBC, blood sugar, electrolyte, kidney and liver function, and cardiac enzymes were within normal range.

The clinical diagnosis was anticholinergic syndrome complicated by intestinal obstruction due to ingestion of the water used to debittered the Lupine seeds. The patient was seen by the on-call surgical team and apart from administration of a rectal enema, he was treated conservatively.

The day after, he was completely asymptomatic. No further tests or interventions were done, and the patient was discharged home.

Conclusion:

Acute anticholinergic syndrome can arise after the consumption of a wide range of plant extracts,  of which lupines (Turmus in Arabic) are an uncommon example.

Lupine seeds need to be well prepared (cooking then soaking with several changes of water over days) to debitter before consumption. The spontaneous bitter taste is mainly due to the presence of a toxic substance with anticholinergic properties.

The Lupine toxicity is clinical diagnosis, it needs high index of suspicion based on history and clinical manifestations.

Treatment is mainly supportive. In severe cases with peripheral and central anticholinergic findings, or persistent features, physostigmine may be considered.

Acknowledgment: We would like to express our great appreciation to Dr. Simon Clarke ED consultant at Hamad Medical Corporation for his help and support.

 

                         

                                                                                

Figure 1:Turmus beans


Mhd Fateh KHAZNAWI, Tarek ALREFAI (Doha, Qatar), Mhd Samir ALSARAKBI
08:30 - 17:40 #11913 - Anticholinergic toxidrome caused by Biperiden( AkinetonR).
Anticholinergic toxidrome caused by Biperiden( AkinetonR).

Case report: A 43-year old male was admitted to the ED a few hours after an

intentional auto-intoxication with 74mg biperiden (=1mg/kg). Clinical examination

revealed an open airway, normothermia, tachypnea, and a tachycardia (120 bpm) with

normotension (129/113 mmHg). He was severely agitated with hallucinations, mydriasis

and urinary retention. Laboratory results showed a mildly elevated CK of 835U/L and

normoglycemia. Toxicology screen on blood was positive for benzodiazepines, which he

used on daily basis. ECG demonstrated a sinustachycardia. Therapy included balanced

fluids (1L Hartmann/8hrs), high-dose benzodiazepines (110 mg diazepam titrated over

6hrs) and bladder catheterization. Physical restraint was required due to severe

agitation and aggression. Physostigmine 0.5mg was administered over 10 min and had a

modest and short-acting effect on the agitation.  Administration was repeated after

30 min with the same effect. The patient was admitted to the ICU for further

observation and received a midazolam infusion (starting at 25mg/h) for several hours

with down-titration overnight.  The symptoms resolved 24hrs after ingestion. Prior

to discharge the patient was assessed the psychiatry team and a close follow-up by

his generalist and psychiatrist was planned. Conclusion: Biperiden is an

anticholinergic drug used for the treatment of Parkinson’s disease and

drug-induced extra-pyramidal effects. Intoxication with biperiden is rare and causes

an anticholinergic toxidrome. The peak effect is reached within 1-2h and its

half-life is approximately 18h. Differential diagnosis of an anticholinergic

toxidrome includes a sympathomimetic toxidrome, acute psychiatric disorder,

delirium, viral encephalitis or malignant neuroleptic syndrome. Treatment of

biperiden overdose consists of supportive measures and symptomatic treatment, with

timely administration of activated charcoal and administration of high doses of

benzodiazepines. Indications for physostigmine use include the presence of

peripheral or central antimuscarinic manifestations without significant QRS or QT

prolongation, i.e. those with convulsions, agitation and hallucinations, delirium,

narrow QRS, supraventricular tachydysrhythmias, hemodynamic deterioration, or

ischemic pain, but its use remains controversial. Physostigmine should be administered in monitored conditions with availability of resuscitation equipment and atropine. The recommended dose is 0.5-2mg, given slowly IV over 5 min. If the agitated delirium reoccurs without

muscarinic effects, physostigmine may be repeated in smaller doses after 20-30min.

 

Take home message

 

Biperiden intoxication is very rare and presents with an anticholinergic toxidrome.

Treatment consists of supportive measures and symptomatic treatment including

benzodiazepines, and may be supplemented with physostigmine.


Karen BEKE (Ghent, Belgium), Cathelijne LYPHOUT, Peter DE PAEPE
08:30 - 17:40 #11891 - Anticoagulant treatment in patients older than 75 years diagnosed of atrial fibrillation in the Emergency Department.
Anticoagulant treatment in patients older than 75 years diagnosed of atrial fibrillation in the Emergency Department.

Introduction:

Atrial fibrillation (AF) increases the risk of ischemic stroke. Anticoagulation is the main preventive tool. The limitations of anti-vitamin K (AVK) have driven the search for other agents with new features; direct-acting anticoagulants (DOACs). The safety of new anticoagulants in elderly patients is unknown but it is advisable to evaluate the associated comorbidities.

 

Objective:

To analyze the type of anticoagulant treatment used in patients with AF diagnosed in the Emergency Department according to their age.

 

Material or patients and method:

Observational, retrospective study developed at the General University Hospital Reina Sofía. We included 761 patients diagnosed with AF attended between October 2012 and December 2013. The type of anticoagulant used (AVK or DOACs) was analyzed and the patients were classified into two groups (≤75 years or> 75 years).

 

Results:

We evaluated 761 patients with AF. There were 405 patients (53.2%) ≤ 75 years and 356 (46.8%)> 75 years. The percentage of males is higher in this second group (57.0 vs 72.8%, p <0.001). Patients > 75 years were more hypertensive (87.9 vs 62.5%, p <0.001), more diabetic (33.4 vs 21.0%, p <0.001), they had more renal disease (13.2 vs 6.9 %, P <0.001), anemic syndrome (14.0 vs 7.2%, p <0.001) and a history of stroke (16.3 vs 6.7%, p <0.001). In addition, they presented a higher result in the CHA2DS2-VASc score (2.9 ± 1.1 vs 1.7 ± 1.4, p <0.001) and in the HAS-BLED score (4.5 ± 1.5 Vs 2.4 ± 1.6, p <0.001). With regard to anticoagulant treatment at discharge, 94 (26.4%) of the patients> 75 years received treatment with DOACs. This percentage is similar in ≤75 years (23,2%, p = 0,31). The AVKs present a similar distribution (37.9 vs 40.0%, p = 0.56).

 

Conclusion:

Although the group of >75 years has more associated comorbidities, they don't present significant differences in the anticoagulant treatment used at discharge compared to the group of ≤75 years. Therefore in these patients, age was not a limiting factor to choose the best anticoagulant treatment.


Danae FERNANDEZ-CAMACHO, Blanca DE LA VILLA ZAMORA, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain)
08:30 - 17:40 #11457 - Antiplatelet to prevent cardioembolic events in non-valvular atrial fibrillation (NVAF)?
Antiplatelet to prevent cardioembolic events in non-valvular atrial fibrillation (NVAF)?

1) Introduction and Objectives:

In the last 5 years, the appearance of direct action anticoagulant therapy prescription and the use of CHA2DS2-VASC risk scale, has improved the percentage of anticoagulated NVAF patients. Even so, antiplatelet drugs are being used in some cases. We review what NVAF patients are treated with antiplatelet therapy considering Guide ESC 2016 recommendations: "Disaggregants can not be recommended for cardioembolic events prevention in atrial fibrillation (AF) patients".

 

2) Material and Methods:

Observational, descriptive and retrospective study enrolled all older than 14 years patients, diagnosed in computerized clinical history of AF or flutter, that were taken after at the emergency departments of hospitals of SALUD Aragon. The period of the study includes from 1st of July to 31st of December 2013, 2014 and 2015. Data were collected with ACCESS and studied afterwards with SPSSv15.

 

3) Results:

Total number of studied patients: 6738. Average age, 75.2 years. Gender distribution: 49.4% male, 50.6% female. Average CHA2DSVASC: 3,1; Average HAS BLED: 1,8. NEW treatment to prevent cardioembolic events: antiplatelet initiated therapy in a total of 507 patients (9,6%). Per years: 2013: in 192 patients (11,6%); 2014: in 162 patients (9,2%); 2015: 153 (8,2%).  Per scale risk CHA2DS2 VASC punctuation: 0 points in 85 patients (17%); 1 point in 43 patients (11%); ≥2 points: in 379 patients (8,6%). Per Hospitals: Hospital B: 4,4% of the patients; Hospital G: 27,3% of the patients were treated, for the first time, with antiplatelet therapy.

 

4) Conclusions:

4.1.- It is seen a result improvement over the years, using less antiplatelet therapy for the prevention of cardioembolic events in NVAF patients, (an 8,2% in 2015), but it is still not at the correct percentage suited by Guidelines (below 5%).

4.2.- High percentage of antiplatelet initiated therapy in patients with ≥2 points at the CHA2DS2 VASC scale (8,6%).

4.3.- Great disparity in the criteria used by Hospitals to initiate antiplatelet therapy, with a significant difference of a 23%


Victoria ORTIZ BESCÓS (Zaragoza, Spain), Marta DEL PUEYO PARRA, Isabel PÉREZ PAÑART, Román ROYO HERNÁNDEZ, Patricia ALBA ESTEBAN, Joaquín GÓMEZ BITRIÁN, Teresa ESCOLAR MARTÍNEZ DE BERGANZA
08:30 - 17:40 #11254 - Aortic dissection and iliac artery occlusion in a middle aged man.
Aortic dissection and iliac artery occlusion in a middle aged man.

Abstract:

Background: Aortic dissection is an emergent disease that needs to be diagnosed as soon as possible. Early diagnosis can reduce the mortality and morbidity of patients. The common signs and symptoms of aortic dissection are related to the site of the dissection. Such symptoms include chest pain, neck and jaw pain, interscapular pain, and abdominal pain. Iliac artery thrombosis is a rare and emergent condition that appears acute, with sudden onset of decreased arterial flow. The symptoms of this include severe leg pain and weakness. It can end in leg amputation.

Case presentation: We present a 54-year-old man, with the sudden onset of weakness of the lower extremities. He was very agitated. Upon examination, we detected the weakness of the dorsalis pedis pulse in both legs, but especially so on the right side. We also detected abdominal tenderness, especially on the periumbilical area. He had vague chest pain too. With a bedside ultrasonography in the emergency department, we could diagnose that he had abdominal aortic flap. After CT scan of the chest and abdominal areas, we found aortic dissection of thoracic and abdominal, with right iliac artery occlusion.

Conclusion: Aortic dissection can occur in conjunction with iliac artery occlusion. So, the sudden onset of lower extremity weakness with lack of pulse or weakness of lower extremity pulse should alert us. The association of these symptoms with abdominal pain or chest pain can guide us to detect aortic dissection with the occlusion of iliac artery.

Keywords: aortic dissection, iliac artery occlusion.


Hamideh AKBARI (Tehran, Islamic Republic of Iran), Alireza JALALI, Atefeh ABDOLLAHI
08:30 - 17:40 #11236 - Aortic mycotic aneurysm. Case report.
Aortic mycotic aneurysm. Case report.

An 83-year-old female, who presents to the emergency department with abdominal pain localized in the left renal fossa of 7 days of onset, stinging, irradiated to ipsilateral iliac fossa, associated to nausea and oral intolerance. No fever. In the ED with TA 165/83 mmHg, HR 86 bpm, Temperature 36 ° C, Respiratory rate 18 rpm, globular abdomen at the expense of abdominal distension, hypoperistaltic, painful palpation in the left iliac fossa, positive left renal percussion. Pyelonephritis is suspected. Tomography of the abdomen and pelvis with intravenous contrast is performed, which documents an infrarenal abdominal aortic aneurysm that extends to the iliac bifurcation, with a loculated paraaortic lesion that resembles collection and left pyelonephritis. It is considered by the ED as an inflammatory or mycotic aneurysm. We call the Vascular Surgery service, and they perform an exploratory laparotomy with resection of infected aortic aneurysm and placement of dacron graft and duodenal repair. A saccular aneurysm of the aortic arch is observed, so an endoprosthesis of thoracic aorta is placed. Positive culture of specimen for Candida albicans.

Mycotic aneurysm of the aorta is infrequent and has high morbidity and mortality due to the recurrence of infection, fulminant sepsis or aortic rupture. Approximately 1% of all aneurysms are associated with an arterial infection. The prevalence is between 0.7% and 2.6%. Infectious aneurysms can occur in any arterial segment and are the most difficult to treat. At present, it occurs mainly as a result of vascular trauma or intravenous drug abuse and usually occurs in patients with some degree of immunosuppression. With preference of the bacteria for the vasa vasorum and the bifurcations of the vessels and arteries of small and medium caliber, affecting in order of frequency: the femoral arteries, abdominal aorta, superior mesenteric. As in this example, it occurs more in the elderly with atherosclerotic disease. The common microorganisms in this entity are: Staphilococcus aureus, Salmonella and Escherichia coli. Unlike in this case, in immunodepressed and IV drug users, any opportunistic germ can be found, however our patient doesn’t t have this criteria. The clinical picture is usually nonspecific and insidious and often the patients have sepsis of difficult control with early and rapid rupture of the aneurysm. Diagnosis is based on clinical suspicion, so primary infection data should be sought and supported by imaging techniques.

This is a unique case because of the patient’s clinical presentation, characteristics and the microorganism isolated.


Ximena OCHOA (MEXICO CITY, Mexico), Tapia XIMENA, Perez De Los Reyes GABRIELA, Saleme ELISA, Ron ADRIANA, Hoyo IRMA
08:30 - 17:40 #10924 - Apical hypertrophic cardiomyopathy diagnosis by point of care ultrasound in the emergency department.
Apical hypertrophic cardiomyopathy diagnosis by point of care ultrasound in the emergency department.

Purpose: Apical hypertrophic cardiomyopathy (AHM) is a variant of hypertrophic cardiomyopathy, involving nearly exclusively apex. It is very common among Asian patients, predominantly in Japanese, which is considered relatively benign condition. However, severe clinical manifestations, including sudden cardiac death, severe arrhythmias and apical infarction have been described in case reports. The electrocardiographic changes (giant negative T waves ) and associated symptoms (chest pain, palpitations, dyspnea…) often present as acute coronary síndromes. AHM diagnosis is based on the demonstration of myocardial hypertrophy in the apical region of the left ventricle, usually by echocardiography with classical image "ace of spades", although in many cases the use of contrast necessary. We present a case of young patient admited at ER with palpitations.

Material & Methods: The most frequent morbid events in Eriksson et al study of AHM were atrial fibrillation (AF), probably related to left atrial enlargement and impaired LV relaxation. It is prudent to also closely examine the heart on bedside emergency echocardiography looking for the  presence of left atrial enlargement.

Results:  37 year old male, with no significant medical history, was admitted to the ER by palpitations. The electrocardiogram showed AF with deep, negative T-waves in leads V3-V6. Bedside emergency echocardiography  (BEE) initially performed to look for left atrial enlargement, revealed apical hypertrophy, with apical cavity obliteration during systole. These findings were confirmed by contrast ecocardiography. The patient was diagnosed with AHM (Yamaguchi's syndrome) and started on beta-blocker therapy.

Conclusion: In this case, BEE helped to identify an AHM. It was the findings on emergency ultrasound, performed and interpreted by EPs, that helped to identify the correct diagnosis and prompted the appropriate consultations to cardiologist, with a final diagnostic of AHM.


Alberto Ángel OVIEDO GARCÍA (DOS HERMANAS (SEVILLA), Spain), Francisco LUQUE SÁNCHEZ, Margarita ALGABA MONTES
08:30 - 17:40 #11186 - Apixaban-associated spontaneous rupture of the spleen: a case report.
Apixaban-associated spontaneous rupture of the spleen: a case report.

APIXABAN-ASSOCIATED SPONTANEOUS SPLENIC RUPTURE: A CASE REPORT

INTRODUCTION

Splenic rupture is a rare life threatening condition. Most cases of are secondary to truama. However sponatenous rupture of the spleen (SRS) has been reported which in most cases are assocaited with infection or neoplasm. Previous cases of SRS has been reported with warfarin but none assocaited with Novel Oral Anticoagulation (NOACs). We present a case of SRS in a 62 year old female on apixaban for Atrial Fibrillation 2 days prior.

 

METHODS

A 62 year old lady Emergency Department (ED) with 1 day history of dizziness, vomiting and feeling weak. She was pale and hypotensive. On examination GCS was 15, BP: 70/50 PR: 80bts/min. Systemic examination was unremarkable. The abdomen was soft and non-tender. Her hemoglobin came back at 8.7g/dl which had dropped from 12g/dl in 2 days. CT-Abdomen showed a large splenic hematoma and thickening of the of the inferior wall of the stomach. The Surgical team was informed and she was then taken for an emergency laparotomy with Splenectomy and Partial gastrectomy. She became septic post-op, responded well to antibiotics and was discharged day 18. The Apixaban was stopped and was discharged on lifelong prophylactic oral antibiotics.

 

RESULTS

 

CONCLUSION 

This case demonstrates the importance of prompt recognition of a spontaneous splenic rupture in a patient on anticoagulation with NOACs. This diagnosis should be considered in any patient on apixaban whom have a  sudden drop in their hemoglobin with no obvious abdominal pain or no history of trauma. Close observation may be done for those patients who are hemodynamically stable, but more invasive treatment should be available and considered if the patient’s condition deteriorates.


Yasser MOHAMED (Galway, Ireland), James BINCHY, Esmael AHMED
08:30 - 17:40 #11696 - Application of Game-based learning for Medical students education of Disaster Medicine.
Application of Game-based learning for Medical students education of Disaster Medicine.

Introduction: The knowledge of disaster medicine included many subjects such as Management Science, Medicine, and  Overall-Planning. The classic teaching method(lecture) is incredibly boring and is difficult for students to learn and memory. Therefore, searching for the methods of disaster medicine education for medical students has become an important topic. Objective: To explore the application value of "Game-based learning" in medical student emergency medical rescue knowledge education. Methods: Based on the knowledge point of the medical student emergency medical rescue knowledge education, we design the Table Game for disaster medicine. After the Table Game course for disaster medicine, a questionnaire survey was done to all the medical students. Results: For disaster medicine education, Game-based learning was priority to traditional lecture in many ways such as interest in learning, class atmosphere, mastery of knowledge, team work and problem solving(p<0.05). Conclusion: Game-based learning method for medical students to study disaster medicine is superior to the traditional lecture and can be used in the education of disaster medicine.


Hai HU (Chengdu, Sichuan, China)
08:30 - 17:40 #10840 - Applying Ultrasonogrophy-guided Peripheral Catheterization with Difficult Access an Evidence-Based Approach.
Applying Ultrasonogrophy-guided Peripheral Catheterization with Difficult Access an Evidence-Based Approach.

Background: Intravenous injection of clinically routine invasive techniques, with chronic diseases, obesity, or increased due to repeated and long-term injections of intravenous injections, thus increasing the difficulty of intravenous injection and children are also intranasal injection of ethnic groups due to emergency Room business characteristics, often need to implement this technology, it is facing critical cases of critical illness, peripheral intravenous injection or family anxiety of emotional reactions, will also increase the pressure on nursing staff and consumption of nursing hours and security expenses. To motivate the discussion of this issue.

Objective: evidence-based, explore ultrasound guided Zhou Bian intravenous injection technology for difficult patients of results.

Methodology: Based on the empirical grade used by Oxford (2010) as the classification, the Cochrane Library, CINAHL PLUS and PubMed 3 databases were selected for data collection. The age was limited to 2007-2017, and then ultrasonographically-guided, sonography- Guided, peripheral venous, peripheral catheterization, Single operation.

Results: Ultrasound guided technique could significantly improve the success rate of first injection (74 ~ 90%) and reduce the number of injections (MD = 1.4 ~ 2.0 ± 0.09 ~ 1.31) in patients with intravenous injection, which were superior to traditional intravenous injection Time still need to spend (MD = 1.06 ~ 27.6 ± 2.5 ~ 19.8).
Clinical advice: Ultrasonic guidance technology using the probe image frequency of 5 ~ 10 MHz, and the need for ultrasound positioning training at least 1 to 2 hours, with the practice of practice> 5 times, help to perform peripheral venous ultrasound guidance technology The success rate.
Restrictions: clinical implementation of peripheral venous ultrasound guidance technology is not much, and the clinical peripheral intravenous injection by the implementation of nursing staff, and nursing staff generally did not accept the training of ultrasound positioning for this limited, hoping to more empirical research Confirmed the success rate of peripheral venous ultrasound guidance technology, to promote the acceptance of this technology to enhance the clinical care division to participate in the study of this technical will and ability to enhance the overall peripheral intravenous care skills evolution. The patient side can reduce the number of pain and enhance the comfort and dignity of the feelings.


Chang WAN-LING, Liu HUI-WEN, Lin SHYH-MIN (YES, Taiwan)
08:30 - 17:40 #10889 - Arrhythmias: not always matters of the heart.
Arrhythmias: not always matters of the heart.

Introduction

Intracranial hemorrhage (ICH) is a life threatening condition which can precipitate electrocardiogram (ECG) changes and arrhythmias. We present a case of a patient which had subarachnoid hemorrhage (SAH) causing arrhythmia and cardiovascular collapse.

Case

A 59 year old Chinese lady was conveyed by ambulance to the emergency department for confusion. She was found confused in the bathroom after she went swimming with her husband. The patient was previously well and had no intercurrent illness. She was known to have nasopharyngeal cancer status post radiotherapy more than 10 years ago.

Upon arrival, she was tachycardic (134 bpm) and hypertensive. Her Glasgow Coma Scale (GCS) was 13 (E3V4M6). Physical findings included a small hematoma over her right forehead, a dilated right pupil, and left hemiparesis.

While awaiting the urgent CT scan, a 12-lead ECG was performed showing ventricular bigeminy. Cardiac monitoring was instituted and the patient developed bizarre idioventricular rhythms and premature ventricular complexes in salvos. An urgent blood gas revealed a potassium of 2.2 mmol/L, which in retrospect given that the formal lab potassium level turned out to be 3.2 mmol/L, was likely an technical error.

A few minutes later, the patient developed pulseless electrical activity arrest. Cardiopulmonary resuscitation and intubation was performed and potassium and magnesium replacement was given. After return of spontaneous circulation, CT brain and Circle of Willis angiogram showed diffuse SAH with intraventricular extension and multiple aneurysms. An urgent extra-ventricular drain insertion was done and she was admitted to the surgical intensive care unit, where she demised 4 days later.

Discussion

There is evidence that SAH can lead to ECG changes and arrhythmias. Some of the underlying mechanisms include autonomic neural stimulation from the hypothalamus or elevated levels of circulating catecholamines[i]. In a study by Di Pasquale et al[ii], it was found that cardiac arrhythmias were seen in up to 90% of patients with SAH. Sinus bradycardia, supraventricular arrhythmias, sinus tachycardia, and sinus arrhythmia were most common.

That patients with arrhythmias are sometimes misdiagnosed and worked up for cardiac or electrolyte causes is worrying as it leads to unnecessary investigations and delay in diagnosis of the underlying ICH. On the flip side, patients presenting with ICH who do not receive cardiac monitoring may develop serious life threatening arrhythmias which may be undetected and further deteriorate into cardiac arrest. This case serves to highlight both that patients with ICH should have at least an ECG and correlating the workup of arrhythmias with history and physical examination is paramount.


Wei Lin Tallie CHUA (Singapore, Singapore), Siang Hiong GOH
08:30 - 17:40 #11073 - Arterial thrombosis in a 37 year old woman with hyperhomocysteinemia.
Arterial thrombosis in a 37 year old woman with hyperhomocysteinemia.

Clinic history:
• Personal history: No allergies. Smoker 40 packs/year. Alcoholism. No other background. No treatments.
• Anamnesis: A 37-year-old woman going to emergency with pain and paresthesias in the left foot that is increasing with intense coldness and distal cyanosis in the last hours.
• Exploration: TA: 145/90, HR: 85 bpm, Oxygen saturation: 98% basal, resting euphonic. Septic mouth. No neurological focal. No jugular engorgement, palpable and symmetrical carotid pulses. ACR: rhythmic without blows or extratons. MVC without pathological noises. Abdomen without interest. MMII: Cold lower left limb with distal cyanosis without showing inferior pulses to popliteus.
• Supplementary tests:
   - Blood Analyze at admission: Hb 11.5 gr / dl, VCM 120, platelets 417000, leukocytes 9200. Coagulation without alterations. Glucose 86, liver profile with GGT 631 and FA 155, rest without alterations. PCR 121.
   - ECG: sinus rhythm at 90 bpm without other findings.
   - Rx chest: Normal.
   - AngioTC: Normal caliber abdominal aorta with mural thrombus in the first cut, another mural thrombus at the infrarenal level. Complete obstruction is observed at the level of the tibio-peroneal trunk of 6.4 cm, which is subsequently recanalized with distal flow observed in the three distal trunks. Popliteal left with complete occlusion in the third sector of 7.8 cm that is recanalized distal to the tibio-peroneal trunk with presence of collateral circulation.
• Evolution:
   - Arterial fibrinolysis is performed with bolus rTPA 20 mg and with continuous infusion 1 mg/hr together with heparin 1000 U/hr in catheter with end in refusal defect and maintained for 24 hrs due to persistent obstruction of the tibialis anterior and peronea In a middle third that is finally solved.
   - Subsequently, a complete study with transesophageal echocardiography has been performed. Descending aortic atheromatosis is seen with small aortic ulcer, plaque fracture, small linear thrombus of 8x30 mm over rupture zone and thrombus that protrudes in vascular lumen and that will improve in respective controls.
   - Extended study during admission showed 55 mmol/L hyperhomocysteinemia along with low levels of folic acid and vitamin B12 that appear to be related to lifestyle and alcohol consumption of the patient. No other findings are found during the study. At discharge, anticoagulation is indicated with acenocoumarol, folic acid, vitamin B12 and pitavastatin.

Conclusions:
Hyperhomocysteinemia may predispose to arterial thrombosis and venous thromboembolism, perhaps by damage to endothelial cells. The most frequent causes of hyperhomocysteinemia are considered to be acquired deficiencies of folic acid, Vitamin B12 and Vitamin B6.
Levels of less than 13 mmol/L are usually considered normal. Between 13 and 60 mmol/L is considered moderately elevated, and from 60 mmol/L is severely elevated.


David NUÑEZ CASTILLO (SPAIN, Spain), Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO
08:30 - 17:40 #11860 - Artificial nutrition evaluation in the ICU: Energy Balance and Protidemia assay contribution.
Artificial nutrition evaluation in the ICU: Energy Balance and Protidemia assay contribution.

ARTIFICIAL NUTRITION EVALUATION IN THE ICU


Fatnassi MERIEM, Khzouri TAKOUA, Ben Jazia AMIRA, Aloui ASMA (Tunis, Tunisia), Sebaii RAFAA, Brahmi NOZHA
08:30 - 17:40 #11433 - As a cause of recurrent pneumothorax, Lymphangiomyomatosis: A case report.
As a cause of recurrent pneumothorax, Lymphangiomyomatosis: A case report.

Background: Lymphangioleiomyomatosis (LAM) is a disease that affects especially young women and usually results with respiratory failure. The frequency of occurrence in the whole population is 1 in a million. It has been reported that the disease is typically seen in women between menarche and menopausal periods but also occurs in women receiving estrogen therapy and in patients with tuberosclerosis. Pneumothorax is frequently encountered clinical presentation during emergency department (ED) admission of these patients.

Case: A 78-year old woman who had previously been treated for gastric bleeding admitted to ED due to syncope and the presence of blood coming from her mouth. Her medical history revealed pulmonary thromboembolism and heart failure diagnoses and she had a history of gastric bleeding treated several times. At the time of admission, her general appearance was moderate, her conscious was clear with normal orientation and co-operation and her vitals were Fever: 36.3 ºC, Pulse rate: 78 /min, Respiration: 20 /min, BP: 147/96 mmHg. Physical examination revealed a minimal incision on the anterolateral aspect of the tongue. Both lungs were normal and no pathological sound was heard, there was no defense, rebound or tenderness on the abdominal with normoactive bowel sounds. Melena was not detected on the rectal examination. In laboratory tests Glucose:135 mg /dl, Kr:1.1 mg/dl, Troponin I:46.6 pg/ml, CRP:13.39 mg/L, WBC:14700/uL, Hb:8.9 gr/dL, D-dimer:4.16 µg/ml, INR:0.99, PTT:21.1sn, pH:7.48, pO2:48.2 pCO2:31.3. Atrial fibrillation and pathologic Q waves in D2, D3, aVF were noted on ECG but no ST-T change was observed. There was no acute pathological change in brain CT. Angio CT due to PTE suspicion (Reinfarct) was reported as diffuse, thin-walled air cysts in both lungs but no thrombus in the main pulmonary arteries or branches was detected (Figure 1). 

Discussion: Respiratory symptoms such as cough, progressive dyspnea, hemoptysis and chyloptysis are predominant symptoms during the clinical course of LAM patients. Pneumothorax which is often recurrent and causes significant morbidity is seen in approximately two-thirds of patients. Such LAMs are often asymptomatic. Physical examination is often normal in the early stages of the disease. If there is no pneumothorax at the time of diagnosis, chest X-ray may be inadequate. Thorax CT, HRCT or MRI can be used for diagnosis.  The gold standard for the diagnosis of LAM is tissue biopsy, showing nodular infiltrates generated by abnormal smooth muscle cells, called LAM cells, in lung or retained lymphatics. The initial approach in ED treatment is the same as other lung diseases and if pneumothorax is detected, it should be intervened by appropriate treatment.

Conclusion: LAM patients are not often admit to EDs but it should be remembered that these patients may have pulmonary complications such as recurrent pneumothorax.


Oğuz EROĞLU, Sinan Oğuzhan ÖZHAN, Hüseyin BALTACIOĞLU, Sevilay VURAL, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #11222 - Ascaris infestation assessing bedside ultrasound by emergency physician.
Ascaris infestation assessing bedside ultrasound by emergency physician.

Purpose: Case study of gallbladder ascariasis complicated with acute hepatitis, diagnosed at Emergency Department, through the use of ultrasonography (US) scanning by emergency physician (EP).

 

Material & Method: A patient with jaundice, with a final diagnosis of Ascariasis infestation assessing US, performed by EP.

 

Results: 16-year-old male suffering malaise and jaundice for two days, without fever. He was hemodynamically stable, with extended jaundice. Abdomen was soft, depressible, painless and non-palpable masses or organ enlargement, no signs of peritoneal irritation. The analytical tests showed AST 1488, LDH 552 and bilirubin of 9.1, along with coagulopathy with INR of 1.88. The emergency physician made an abdominal ultrasound scan, which showed an echogenic tubular image without posterior acoustic shadowing, mobile, several centimeters long and about 6 mm in diameter, compatible with helminth infestation. The patient was admitted to the Infectious Diseases Unit. Within 24 hours of admission there was a rapid and progressive deterioration of the liver and renal function, and progressed to severe acute liver failure, requiring an urgent liver transplant.

 

Conclusions: Ascaris lumbricoides is the largest and most predominant of the human helminths. Infection occurs by ingestion of the embryonated eggs. The released larvae from the eggs in the intestine pass through a pulmonary migration phase for maturation. The larvae attain sexual maturity within three months after reaching the small intestine. It is proven that ultrasound can diagnose this worm infestation hepatobiliary in up to 84% of cases, it may however, fail in cases where the parasite has died or the visualisation is hindered by the presence of stones.

Ascariasis of the gallbladder is a very rare occurence and its relationship with acute hepatitis has not been well studied. Therein lies the importance of this case, along with the news of the diagnosis of a case of this type, for the use of ultrasound by the emergency physician.


Francisco LUQUE SÁNCHEZ (Seville, Spain), Margarita ALGABA-MONTES, Alberto Ángel OVIEDO-GARCÍA
08:30 - 17:40 #11644 - Assesment of polytrauma severity using scoring systems.
Assesment of polytrauma severity using scoring systems.

Background: Injury is a global public health problem and the dominant cause of morbidity and mortality among the young, particularly in industrialized countries. Numerous scoring systems have been developed for trauma. Trauma scoring tools include anatomically-based systems, physiologically-based systems and combined anatomically- and physiologically- based scoring systems. The most frequent scores used in trauma are: Glasgow Coma Score (GCS), Revised Trauma Score (RTS) and Injury-Severity Score (ISS).

Methods: This is a retrospective study, based on data drawn from SMURD (Mobile Emergency, Resuscitation and Extrication Service) and the Clinical Emergency County Hospital of Sibiu, involving patients injured and then admitted between January 2014 and December 2016. The analysis includes 108 patients. For these patients, we have calculated the RTS score considering GCS, the respiratory rate (RR) and the systolic blood pressure (SBP), using the following equation: RTS=0.9368*GCSc+0.7326*SBPc+0.2908RRc,where ”c” represents a coded value between 1 and 4, known from a table based on the parameter value. The RTS values range from 0 to 7.8408, with a higher value indicating increased probability of survival (Ps). After calculating the RTS in the prehospital sheet, we have looked for the final diagnosis after the emergency assessment to observe the evolution of the patient, correlated to those two data. Another score used in trauma is ISS.  For each body region - head and neck, face, chest, abdomen, extremities (including pelvis) and external - we assigned an AIS code (Abbreviated Injury Scale), from 1 to 6.

Results: We’ve evaluated 108 patients aged between 8 and 89, averaging 40 years. Out of the lot, 73.1% were men, whilst de remaining 26.9% were women. By calculating the RTS score, we notice that 83% of the patients have near-maximum chance of survival, over 90%, 4% have 80% chance of survival, 30% chance of survival was attributed to 1% of the patients, 2% of the lot were calculated with 17% chance, while  2% have been scored with extremely low chance of survival, between 4-7%. On the other hand, the ISS score shows 38% are unlikely to cause death, 22% noted with critical values, 33% - linear increase in mortality, 6%-50% probability of mortality, 1% nonsurvivable injury. Tracking patients’ evolution in the emergency department, we notice that 6% of the patients have died in the ER, 81% of the lot were admitted to one of the adjacent departments: surgery, orthopaedics and traumatology, neurosurgery. An additional 2% were transferred to other medical centers and 11% were discharged with instructions/recommendations.  

Discussions:  By comparison between a score based on physiological parameters on spot (GCS, RR and SBP) and an anatomical score (ISS), we notice that the patients’ chances of survival are way higher in RTS compared to ISS. By taking age into consideration, we may have found a reason for a higher RTS score.


Prisacariu IRINA, Muresean IRIS CODRUTA (Sibiu, Romania), Ardeleanu VICTORIA, Ciorogariu PETRUTA-IOANA, Dendrinos GABRIELA DIANA, Ifrim SORIN, Piturlea COSMIN CONSTANTIN, Stoica CONSTANTA
08:30 - 17:40 #11390 - Assessing diagnostic accuracy of ultrasound machine in prescription of thrombolytic for patients with massive pulmonary embolism in emergency department.
Assessing diagnostic accuracy of ultrasound machine in prescription of thrombolytic for patients with massive pulmonary embolism in emergency department.

Background:Undiagnised and untreated Pulmonary Thromboembolism (PTE) results in high mortality. Echocardiographic assessment is a current vastly used technique in diagnosis of PTE. However, patient’s instablity of situation may provoke a need for faster diagnosis and treatment and lack of access to a cardiologist in emergency department might slowen the procedure.

According to the latest case reports, an emergency medicine specialist is abe to reach favorable results using ultrasonography machine.The purpose of this study is to assess diagnostic accuracy of ultrasound machine in prescription of thrombolytic for patients with massive pulmonary embolism in emergency department.

 

Methods:This is a cross-sectional study of patients suffering PTE, attending emergency department of Emam Reza hospital (Edalatian) within six monthes. All patients were assessed simultaneously by a cardiologist and an emergency medicine specialist. Both diagnostic methods were assessed according to the presense of four signs including right ventricular dilatation, Mc connell’s sign, hypokinesia of right ventricle and septal paradoxal movements. Results were evaluated using SPSS software (V-19) . Sensitivity, specificity, true positive and negative rates were calculated based on echocardiographic results.

 

Results:28 patients (17 male and 11 female) were included in the study. The most common abnormal finding was right ventricular dilatation ( 71% in sonograghy and 89% in evhovardiography), followed by septal paradoxal movements and Mc connell’s sign. Sensitivity, specificity, true positive and negative rates of right ventricular dilatation using sonography were assessed to be  80%, 100%, 100% and 37.5 % respectively. And for McConnell's sign the numbers are 67%, 85%, 83%, 69% respectively. In the same manner, the results for hypokinesia of right ventricle are 45%, 75%, 82% and 35%. And for the septal paradoxal movements the results are 57%, 71%, 86% and 36% respectively.

 

Conclusion:According to the present study, using ultrasonography machine in emergencies is considered to be an appropriate adjunctive utility accompanying echocardiography in diagnosis of cardiac problems resulting from thromboemboly.

 

Keywords:

Pulmonary thromboembolism, echocardiography, ultrasonography, right ventricular dilatation, Mc connell’s sign, right ventricular hypokinesia, septal paradoxal movements.


Hamideh FEIZ, Raheleh FARAMARZI (Mashhad, Islamic Republic of Iran), Mohammad Davood SHARIFI, Mojtaba FAZEL, Ramezani JAVAD
08:30 - 17:40 #11481 - Assessing FAST sonography accuracy done by emergency physician in blunt abdominal trauma Abstract.
Assessing FAST sonography accuracy done by emergency physician in blunt abdominal trauma Abstract.

Focal assessment sonography is replacing DPL in examinating patient with blunt abdominal trauma gradually .in addition non-radiology physician can perform FAST to improve pation care .assesment pationts with blunt abdominal trauma in emergency department is a problem .specially the assesments and the resusitation of trauma pationts shold be fast .therfor FAST ecan is a suitable diagnostic tool on experienced hands. Emergency physition have used FAST for years .this research was run to evaloate the ability of emergency medicin resident bat pations in comparison to radiology assistants.

Methods:

Across sectional study was doun during three months in tow teaching hospital in tehran iran .Firstly pationt was assessed by an emergency resiedent then a radiologhy resident did FAST .Oral and intravenus contrast-enhance abdominal compioted topograghy CT scanwere applide as refrfenc standard.sencitivity and espicifity FAST of ultrasound determindby any of the groups tothe CT scan.

results:

200 pationt(107 men and 93 women) with the mean age age of30.99+_8 yearswith complaint of abdominal trauma were inclouded .In emergency medicin reports only 16 out of 200 cases(8)were abnormal ,indicating freeabdominal flouid .radiology reported 19 case of abdominal flouid ct scan shoud 18cases of free abdominal flouid. in emergency resident reportthe sencitivity and spicifity 77.77 and 98..90 respectivly .on the other handin radiologhy group had sencitivity of 88.88 and spicifity of 98.35

coclusion:

finally,according to the finding of the study it can be cocluded the fast ultrasoun performed the emergency residentin patient with blant abdominal trauma is accebteble method to detect fiouid in abdominal cavity


Seyed Mohammad HOSSEINI KASNAVIEH (tehran, Islamic Republic of Iran), Seyed Hossein SHAKER, Hossein SAIDI, Gholamreza MASOUMI, Nader TVAKOLI, Hassan AMIRI
08:30 - 17:40 #11137 - Assessing the use of imaging in paediatric trauma patients.
Assessing the use of imaging in paediatric trauma patients.

Background and objectives

Exposure to ionising radiation represents an increased cancer risk for children. Also the mechanism, severity and management of injuries are different in children compared to adults. Therefore, an alternative approach to imaging in paediatric trauma is necessary. The recent (2014) guidelines of the Royal College of Radiologists (RCR) and the National Institute of Clinical Excellence (NICE) regarding imaging in paediatric trauma reflect the same, advocating judicial use of chest and cervical spine imaging. The objective of this study was to examine whether emergency departments across the East of England Trauma Network use the updated guidance in C-spine and chest imaging for paediatric trauma.

Methods

A questionnaire-based survey was sent to all the hospitals in the East of England Trauma Network to be completed by emergency doctors of any grade. We collected data about the grade of doctors responding and local guidelines used for paediatric trauma imaging. In addition we included a set of six hypothetical scenarios reflecting changes in imaging guidance. For the scenarios the participants were asked to choose what imaging modality they would use (none, plain radiograph, CT, MRI). Examples of these scenarios include: a) a child in a road traffic collision with GCS 12 at the scene, breathing in air, with blocks immobilising the spine, b) a child whose plain films are normal but there is continued clinical suspicion of injury, c) In your practice what is the first-line imaging modality used to assess blunt chest trauma in an unconscious child?

Results

49 ED doctors completed the survey. Analysis of the results showed that a range of different guidelines are used across the region, and 21 respondents (n=49) did not use any specific guidelines. The answers to the scenarios showed that the choice of imaging modalities was largely consistent with the recommendations of NICE and RCR in four of the six scenarios. In two of the six scenarios [b) and c)], the choice reflected the lack of explicit guidance about these clinical situations. However, there was no increased risk of exposure to imaging modalities with higher radiation doses in these particular cases. In fact, comments from several respondents showed that they would like to make more use of MRI, however, organising an MRI is often not possible without delay.

Conclusions

The results of the survey show that there is inconsistent use of national guidelines for C-spine and chest imaging in paediatric trauma. Furthermore, the results demonstrate a need for more clarity in national and regional guidelines. Additional data collection to examine the impact of adherence to guidelines on clinical outcomes represents an exciting future direction for this work.


Maria PREUSS (Cambridge, United Kingdom), Helen BAILIE, Shruti AGRAWAL
08:30 - 17:40 #11295 - Assessment of chemical disaster preparedness among remote oil field clinics medical staff in Eastern province of Saudi Arabia in 2015.
Assessment of chemical disaster preparedness among remote oil field clinics medical staff in Eastern province of Saudi Arabia in 2015.

Abstract

Background:  Hazards of chemical disasters are continuing to increase especially in industrial oil fields. The number of chemical manufacturing facilities and the presence of large quantities of toxic chemicals and hazardous substances among population pose a significant threat to global health and environment.

Objectives:  This study was done to assess preparedness towards chemical disaster among medical staff in remote oil clinics in 2015.

Methodology:   This is a descriptive cross-sectional hospital study.  The population targeted in this research are doctors, nurses and paramedics who work in remote oil clinics in eastern provenance of Saudi Arabia in 2015.

Results:  The total number of 150 participants included in our study .It is noted that nurses are more common to this study 98 (65.3%), the bachelor degree is the most prevalent 75 (50.0%). The age group of 30-39 years is the most common 62 (41.3%).   The number of years which is working in remote area clinic:  the range in less than 5 years was 87 (58.0%), and improved in 5-10 years were 45 (30.0%) attending the lecture in chemical disaster noted that more than a year ago was 70 (46.7%) and less in 6 month and who   reading articles or book in chemical disaster is more common in more than a year ago were 47 (31.3%); according to   utilizing the internet resources to read in chemical disaster is more common in within last 6 months were 56 (37.3%) and also who participated in inside of clinic disaster were 39 (26.0%).  Also within the last 6 month who receiving training/in service on how to use PPE (Personal Protective equipment) was 88 (58.7%), also who receiving training on how to use SCBA full face-piece ( self-contained breathing apparatus) within last 6 months was 49 (32.7%).

It is noted that the difference statistically is not significant in correlation between rate the clinic ability and the number of years working in remote area clinics (P value 0.297)

Conclusion:  The medical staff is not well prepared to take an effective action in case of a chemical disaster.  The essential knowledge of the medical staff in all investigated aspects of chemical safety has been found out to be not satisfactory. The majority of the study population of age group between 30-39 years and had less than 5years work in remote area clinics.


Mohmmad KAROUM (Omdurman, Sudan), Hany EBEID, Michel DEBACKER
08:30 - 17:40 #11775 - Assessment of community acquired pneumonia with fine’s score and a radiological score.
Assessment of community acquired pneumonia with fine’s score and a radiological score.

Introduction: Community acquired pneumonia (CAP) is a frequent leading cause of hospital admission worldwide. Through this study we investigate the accurancy of Murray radiological  score (RS) associated to Fine score (FS) as a triage tool for CAP in the emergency department.  

Methods: a prospective observational study including patients admitted in an emergency department of a general teaching hospital for a CAP. FS and RS were calculated on admission and we analysed the rate of hospitalization and outcome at 30 days and analysed  the correlation between the two scores. Statistical analysis were based on Chi 2 test with significant statistical difference (SSD) if p < 0,05.

Results: 174 CAP, 104 men and 70 women, mean age = 57,5 ± 17,7 years. RS was 3 ± 0 in FS class I (n = 6), 3.6 ± 1.4 in class II (n = 46), 3.54 ± 1.5 in class III (n = 40), 4.1 ± 2 in class IV (n = 67) and 4.33 ± 2 in class V (n = 15).  Among patients who were hospitalized in medical ward, 60% of them belongs to class I, 83.3% to class II, 53.4% to class III, 15.1% to class IV and 16.6% to class V. 17.5% of patient hospitalized in ICU had a fine score class III , 52.8% had a class IV and 41.1% had a class V. Checking out  was possible for 40% of patients in class I, 13.9% in class II, 22.6% in class III and 11.3% in class IV. Mortality ranged from 2.8% in class II to 41.7% in class V.

We found an association  between FS and RS (r=0.16, p=0.034). The RS in survivors versus  not survivors in the FS categories was respectively 3.46± 1.3 vs 5±1 in class II, 3.25 ± 1 vs 5 ± 2.4 in class III, 3.7 ± 1.7 vs 4.8 ±2.3 in class IV and 4 ±1.3 vs 5 ±2.5 in class V. There was a SSD only in category II (p = 0.01).

Conclusion: Radiological score may improve Fine score. Further studies with larger cohort are necessary to show better results.

 


Mohamed Amine KALLEL (tunis, Tunisia), Zaouche KHEDIJA, Maghraoui HAMIDA, Mohammed Chekib BOUALI, Majed KAMEL
08:30 - 17:40 #11387 - Assessment of emergency physician clinical judgment accuracy in severity and discharge criteria in comparison with peak flow metery in patients with asthma attack.
Assessment of emergency physician clinical judgment accuracy in severity and discharge criteria in comparison with peak flow metery in patients with asthma attack.

Background:

In the emergency department, admission or discharge decisions are based on clinical symptoms and physical examination. The aim of this study is the Comparison of Assessment of emergency  physician clinical  judgment  accuracy with actual amount of peak expiratory flow rate (PEFR).

Method:

Our research was a cross-sectional study. In this study, 138 patients with asthma by the age of 18 to 55 years were enrolled. From admission to discharge, Clinical signs and symptoms investigated and recorded by emergency  physician then determinate the severity of asthma (mild, moderate, severe). In both stages (admission and discharge) the PEFR was measured by the researcher and compared with severity of asthma (determinate based on clinical symptoms and physical examination).

Results:

37.7% patients were male and the rest were women and the mean age of participants was 49.84 years. The number of cases of mild, moderate and severe asthma were 14, 36 and 88  , respectively in peak flow meter. The number of cases of mild, moderate and severe asthma were 37, 32 and 69  , respectively in clinical judgment. In Assessment of emergency  physician clinical  judgment  accuracy in severity of asthma  in comparison  with  peak  flow  metery the result was the kappa value 0.231 (P <0.001).

Conclusion:

The study showed that clinical judgment of physicians in the emergency department is not a good predictor for prediction of severity of asthma.

 

Keywords:asthma  attack, peak expiratory flow rate, clinical judgment


Raheleh FARAMARZI, Mohammad Davood SHARIFI (Mashhad, Islamic Republic of Iran), Hamid Reza RAHMAT ZADEH
08:30 - 17:40 #11808 - Assessment of imminence of unplanned out-of-hospital deliveries.
Assessment of imminence of unplanned out-of-hospital deliveries.

Introduction:

  The extra-hospital unexpected delivery is an obstetric-pediatric emergency. Medical tools to determine the imminence of unplanned out-of-hospital birth have not been validated.

The main goal of this study was to analyze assessments of the imminence of these deliveries, by methods such as the Manilas score and the need to push

Patients and method: This was a prospective descriptive study. We searched the MECU-database for all women who gave birth outside the maternity ward with or without the assistance of EMAS teams related encounters registered during 3 months. The results of our study were gathered in an Excel table.

 Results:

 we included Fifteen unexpedcted deliveries. Eight (53%) deliveries occurred in the presence of the SMUR and seven (47%) had already given birth or before the arrival of the mobile emergency care unit (MECU). Risks of unplanned out-of-hospital deliveries represented 1.9% of the calls during the study period.

The mean age was 31 years with extremes ranging from 21 to 47 years.The Malinas score was used for dispatching in only 13% and was not used for intervention in any case. It was estimated that the need-to-push feeling was used for 48% (dispatching) and 44.8% (intervention) of patients. Its sensitivity, specificity and predic-tive values were higher than those of the Malinas score in dispatching and substantially higher in intervention.

14 newborns had an Apgar score of 10; only one stillbirth was recorded with an Apgar score at 0. The average glycemia was 0.82 g / L ± 0.2.

Fifteen women were transferred to a maternity center and 14 newborns were admitted in neonatology service.

Conclusion:

These results argue for the development of tools for estimating the imminence of unplanned delivery. Such tools should be applicable in extra-hospital emergency situations to ensure their use in practice.


Wided BAHRIA (tunisie, Tunisia), Hela MANAI, Saida ZELFANI, Syrine KESKES, Wafa LIMAM, Mylene BEN HAMIDA, Mounir DAGHFOUS
08:30 - 17:40 #11212 - Assessment of paramedics’ cognitive abilities and technical skills in spine immobilization.
Assessment of paramedics’ cognitive abilities and technical skills in spine immobilization.

Background:

Cervical spine trauma is frequent among trauma patients and is a major public health problem. Spine immobilization is the first procedure of the initial management of patients with a potential injury to the cervical spine in emergency department (ED)

The objective of our work is to assess the knowledge and the technical skills of  paramedics in cervical spinal immobilization.

Methods:

This was a descriptive observational study conducted in the ED that included 44 paramedics. Firstly, self-reported questionnaire survey was distributed, then a practice test using a standardized sheet allowed assessment of technical competencies. The results were analyzed with Microsoft Excel.

Results:

Cognitive abilities:

70% of the students consider that senior supervision in ED is satisfactory. However, they made some suggestions to improve the management of spinal trauma: 75% asked for continuing practical training, 18.8% asked for theoretical lessons and 7% asked for a longer training period in prehospital emergency department.

Only 20.45% of students have already performed spinal immobilization in trauma patients. The resources previously used were: cervical collar (86.36%), spinal board (60%) and vacuum mattress (60%). Cervical collar and spinal board's indications were cited by the majority of paramedics. Concerning clinical assessing and managing vertebral column and spinal cord injuries, 70% mentioned the importance of neurological examination, only 30% mentioned the need of monitoring vital signs and  17% mentioned pain assessment. and treatment. 54% of paramedics mentioned the need of applying manual in-line stabilization (MILS).The need of a good coordination between team members and the respect of ergonomics rules when moving patient was only mentioned by 9% of the investigation group.Technical skills:All candidates respected the different stages of cervical collar placement with a success rate of every step between 50 and 100%. The same results were observed for spinal board placement.Conclusion:

The management of patients with a spinal injury starts at the scene and continues through to rehabilitation in order to minimize the risk of secondary injury and maximize the potential for recovery.  The management of vertebral column and spinal cord injuries requires an interdisciplinary team approach. Paramedics have a crucial role in initial assessing and managing of spinal injuries and in spinal immobilization which might avoid complications. Continuous training program for all emergency staff seems essential to maintain cognitive and technical abilities of these primary survey actors in the ED.


Majdi OMRI, Hajer KRAIEM (Sousse, Tunisia), Sami BEN AHMED, Amal BACCARI, Mohamed Aymen JAOUADI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11012 - Assessment of preparedness of hospitals & healthcare providers regarding radiological emergenccies at northern emirates states.
Assessment of preparedness of hospitals & healthcare providers regarding radiological emergenccies at northern emirates states.

RESEARCH IS ATHESIS APPROVED BY  EMDM TO ACIEVE THE DGREE


Alaaeldin ABDULKAWY (ALEXANDRIA, Egypt)
08:30 - 17:40 #10549 - Assessment of prognosis in head trauma patients by Madras Head Injury Prognostic Scale (MHIPS).
Assessment of prognosis in head trauma patients by Madras Head Injury Prognostic Scale (MHIPS).

Background Traumatic head injuries are the most common cause of mortality and disability among patients suffering trauma. Applying proper trauma scoring systems plays an important role in the management of these patients thus by means of special treatment guidelines, we can improve traumatic patients’ prognosis.

Objective To determine prognosis in head trauma patients by Madras Head Injury Prognostic Scale (MHIPS) and to compare this scale with Glasgow Outcome Scale (GCS) at discharge.

Methods In this cross-sectional study we evaluated 117 patients with head trauma who were admitted in Shahid Mohammadi Emergency Department (ED) in Bandar Abbas. MHIPS (containing 6 prognostic factors) was used to determine patients’ prognosis at the initial visit in the ED. We used GCS in order to measure patients’ outcome at discharge. All patients’ data were recorded through questionnaire with two separate section: Demographic and Clinical data. We compared the correlation of these two prognostic scales.

Results Of 117 patients, 98 (83.8%) were male and 19 (16.2%) were female. The mean age range of patients was 31.15±17.7. 61 patients (52.1%) had intracranial injuries with subdural hematoma (SDH) being the most common. The highest rate of full recovery (67 patients (87%)) was observed in the group with MHIPS score above 15 and the highest rate of mortality (26 patients (86.7%)) was observed in the group with MHIPS less than 12. There was a significant difference between the two scale when comparing patients’ prognosis (p-value<0.001). MHIPS had correctly estimated patients’ prognosis in 92.3% of cases.

Conclusions: MHIPS has the ability to determine patients’ prognosis in head trauma with high sensitivity and specificity. Thus, it is suggested that an appropriate scale like MHIPS should be provided for the emergency physicians to determine patients’ prognosis in head trauma


Ashkan TABIB ZADEH (Bandar Abbas, Islamic Republic of Iran), Reza YAZDANI, Saeed HAYATI, Morteza SAEEDI
08:30 - 17:40 #10959 - Assessment of the management of infectious meningitis and meningoencephalitis in a French emergency unit.
Assessment of the management of infectious meningitis and meningoencephalitis in a French emergency unit.

Introduction. Meningitis and meningoencephalitis, especially bacterial or herpetic ones, are severe infections who can lead to disabilities or even death in case of non optimal treatment. The first role of the emergency physician is to quickly identified viral from bacterial meningitis. However, some uncertainty in the sequence of initial diagnostic procedures may delay the administration of the appropriate treatment and moreover, delay antibiotics first dose. The objective of our study was to assess the management of these patients in our emergency department.

Methods. We conduced a retrospective, monocentric, observational and descriptive study from January 2009 to December 2015. All patients admitted to the ermergency department for meningitis or meningoencephalitis were included. The primary endpoint was the median time between management and administration of antibiotics.

Results. Of the 276 patients included, 46% had the fever-headache-stiffness triad. The median age was 47.3 years (Inter-Quartile Range (IQR): 28.2-64.2). Twenty patients (7.2%) had sepsis (qSOFA≥2) and 2 (0.7%) experienced septic shock. The diagnostic procedure distinguished 64 (23%) patients suspected of bacterial etiology, 158 (57%) of viral etiology and 54 (20%) unspecified. A cerebral scan was performed for 150 patients (54%) before lumbar puncture. The median time to perform lumbar puncture was 4.78 hours (IQR= 2.57-7.3) and the appearance was cloudy for 31 patients (11%). Patients with an abnormal cerebrospinal fluid received C3G in combination with amoxicillin in 75% of cases, and with aciclovir in 29%. When a viral origin was suspected by the clinician, 40% of the patients were not treated. However, in the case of viral encephalitis or meningoencephalitis, only one patient haven’t be treated with aciclovir. In case of suspected bacterial meningitis, the median time to first antibiotics was 5.15 hours (IQR = 2.03-7.52) after admission and 1 hour (IQR= 0.22-1.97) after the lumbar puncture. Interestingly, only 53% (N=145) of the emergency diagnosis was consistent with the final diagnosis.

Conclusions. Our study showed that the delay in the management of meningitis and meningoencephalitis in the emergency department did not respect the guidelines deadline for treatment. Particularly, it seem that the time required to perform the lumbar puncture could be the the reason for increasing treatment delay.


Farès MOUSTAFA (Clermont-Ferrand), Sonia AJIMI, Loic DOPEUX, Céline LAMBERT, Marjolaine BOREL, Christophe PERRIER, Julien RACONNAT, Jeannot SCHMIDT
08:30 - 17:40 #10931 - Associated factors of hypothermia in multiple trauma patients - A prospective analysis of the international alpine trauma registry.
Associated factors of hypothermia in multiple trauma patients - A prospective analysis of the international alpine trauma registry.

Aim: The aim of this systematic analysis of the International Alpine Trauma Registry was to identify associated factors of hypothermia in patients sustaining multiple trauma in alpine or wilderness environment.

Methods: Patients included into the International Alpine Trauma Registry between 2011 and 2013 were analysed. This registry is a prospective, comprehensive multicentre study implemented to collect data based on the Utstein Style Protocol from multiple trauma patients rescued from alpine or wilderness environment. An exploratory data analysis was performed using a classification tree with CHAID, CRT, multinomial logistic regression and One-way ANOVA.

Results: A total of 104 patients (15.4% female and 84.6% male) were included into the study; overall mortality was 13.5%. According to their body core temperature (mean 31.0°C±5.3°C) patients were divided into three groups: group 1 ≤31,0°C (9,1%), group 2 31,1°C – 35°C (49,1%) and group 3 ≥35,1°C (41,8%). The exploratory data analysis using CHAID identified primarily external factors like avalanche burial (p=0.004), winter season (p=0.023) to be associated with hypothermia. Secondary classification associated internal factors like severely impaired coagulation (INR > 1.3) (p=0.025) with the presence of hypothermia. Considering the severity of a critical multiple trauma, hypothermia was related with a lower injury severity score (ISS) 16-49 (p=0.011). Logistic regression identified further shock related factors like lower systolic blood pressure (p=0.001), severely impaired coagulation (INR > 1.3) (p=0.025) and higher arterial base excess (p=0.005) to be associated with hypothermia.

Conclusion: This systematic review of accidents in an alpine or extra-urban terrain identified environmental factors (avalanche burial and winter season) and accident associated factors like severe anaemia and shock as associated factors for hypothermia in the multiple trauma patient. In the present study, patients with an ISS

Outlook: A subsequent analysis including a larger number of cases is planned to further explicate the critical role of accidental hypothermia for multiple trauma patients. Furthermore, an in-vitro study, elucidating the effects of hypothermia on coagulation in an experimental setting is currently in progress.


Bernd WALLNER (Innsbruck, Austria, Austria), Markus FALK, Simon RAUCH, Martin PALMA, Giacomo STRAPAZZON, Hermann BRUGGER, Peter MAIR
08:30 - 17:40 #11783 - Association between length of stay in the Emergency Department and 30-days in-hospital mortality: a systematic review and meta-analysis.
Association between length of stay in the Emergency Department and 30-days in-hospital mortality: a systematic review and meta-analysis.

Introduction: It is known that overcrowding, length of stay (LOS) and boarding in the Emergency Department (ED)  increase the risk of patient safety events and increase patient dissatisfaction. The effect of EDLOS on patient in-hospital mortality (IHM) remains unclear.

Objectives: Our main objective was to systematically review the literature for evidence on the association between EDLOS and 30-days IHM.

Methods: Articles selected were focus on the association between EDLOS and 30-days IHM. Literature search strategies used MeSH and text words related to EDLOS. Search was performed on Medline, Embase, Cochrane Library, Web of Science, CINAHL and PsycNET. The selection of articles was done with F1000 software. Two reviewers independently screened the titles and abstracts yielded by the search to identify relevant abstracts. Full articles with the title or abstract meeting the inclusion criteria were retrieved and the reviewers selected those that meet inclusion criteria. Data extraction included study characteristics, prognostic factors, outcomes, and 30-days IHM. After the systematic review, we performed a meta-analysis using the Mantel–Haemszel method and the DerSimonian Laird estimator for the estimation of heterogeneity with tau2 and I2. The cut off of the EDLOS was 8 hours (<8 hours or >8 hours). Odds ratio were combined by using the inverse variance method.

 

Results: From 3,577 references screened by the two independent reviewers 135 references were selected. After the first step of exclusion of references that didn’t match with the search, 68 papers were selected. Finally, after the last round of screening, the reviewers selected 5 papers. The total number of patients included was 119,174. The random effects model found an OR of 0.98 with CI [0.79; 1.21] and a p-value of 0.8505. The heterogeneity was high with Tau2 of 0.0342 and I2 of 83%.

Conclusion: Our systematic review and meta-analysis didn’t find an association between EDLOS and 30-days IHM. There is no increase in mortality in patients staying more than 8 hours in the ED. Because of a high heterogeneity, further large and multicenter studies are needed.


Dominique LAUQUE, Gregoire VERSMEE (Boston, USA), Michel CUCHERAT, Mohamed ALSABRI, Jacqueline CELLINI, Michel PHILIPPE, Houze-Cerfon CHARLES HENRI, Niels RATHLEV, Shan LIU, Carlos Arturo, Jr CAMARGO, Martin MOECKEL, Anna SLAGMAN, Christ MICHAEL, Singer ADAM, Jonathan EDLOW, Richard WOLFE, Pr Abdelouahab BELLOU
08:30 - 17:40 #11508 - Association between number of ambulance visits to children with asthma and weather changes during period from 2010 to 2012 in Latvia.
Association between number of ambulance visits to children with asthma and weather changes during period from 2010 to 2012 in Latvia.

Aim:

To clarify the relationship between number of ambulance visits to 0 to 18 years old patients with asthma and weather conditions - air temperature and relative humidity.

Topicality:

5–10% of the population suffer from asthma – it affects approximately 300 million individuals worldwide. Asthma is the most common chronic disease in children – about 7 million children have asthma. Asthma cannot be cured, but it can be controlled and patients can live a wholesome life.

Material and methods: State Emergency Medical Service records of 0–18 years old asthma patients (n = 1 031) were analysed during the period from 2010 to 2012. Meteorological monitoring data (average temperature and relative humidity) from 23 monitoring stations of Latvian Environment, Geology and Meteorology Centre were used.

Conclusions:

  1. The largest number of ambulance visits were performed to 0 to 5 years old patients – 481 ambulance visits or 46.7%;
  2. Number of ambulance visits statistically significantly differs by gender and age (χ2=37.88, p=0.003, df=17). 66.8% or 689 visits were to boys and 33.2% or 342 visits to girls;
  3. The largest number of ambulance visits were performed in September – 16.6%  (n = 171);
  4. 94 % or 970 ambulance visits were made when 3 days average relative air humidity was above 60%;
  5. Statistically significant difference was observed in number of ambulance visits in different groups of 3 days average temperature and relative humidity. The largest number of ambulance visits were observed when 3 days average temperature was from  +10,1ºC to +20ºC and relative humidity was above 60% – 41.1% (n = 399), (χ2= 23.1; P<0.001; df=5);
  6. The largest number of ambulance visits - 77,3% (n – 797) were performed out of GPs working time between 5:00pm – 8:00pm and in holidays:
  7. Asthma patient health care in primary health care level has to be sustained and promoted to improve asthma control for children.

Anna BUZA, Dace KLUSA (Riga, Latvia), Svetlana LAKISA
08:30 - 17:40 #10181 - Association between the mortality rate and the first 24 hours of blood pressure measurement of cerebral vascular accident in a tertiary hospital.
Association between the mortality rate and the first 24 hours of blood pressure measurement of cerebral vascular accident in a tertiary hospital.

Objective: Evaluation of the mortality rate (MR) and its association with the blood pressure levels (BP) in the first 24 hours of an hemorraghic cerebral vascular accident (H CVA) of patients in the ICU of the Clínicas Hospital Complex of UFPR (CHC – UFPR) and, among the survivors, evaluation of the consequences by using scales of Rankin and Barthel

Methods: Analytical, retrospective and observational study of 47 medical records of patients hospitalized in the Adult ICU of the CHC-UFPR with diagnosis of H CVA in the years 2012, 2013 and 2014.The patients were divided in 3 groups according to the arrival systolic blood pressure (SBP). The group 1: SBP between 110-140 mmHg, group 2: between 140-180 mmHg, group 3: above of 180 mmHg. Three functional scales were used to analyses the results: Glasgow coma scale, Barthel index and modificated scale of Rankin. 

Results: Among the 47 patients, 25 developed to death (53,19%). The group 1 with 7 patients in total showed the highest MR (71,42%), followed by the group 3 with 19 patients (52,63%) and, the last one, the group 2 with 21 patients (47,61%). In the evaluation of the modificated scale of Rankin the values were from 1 (10%) to 5 (20%) and for the Barthel index were from 5 (5%) to 100 (11%).   

Conclusion: The BP levels in the first 24 hours of an H CVA could not work alone, however in assotiation with age, days of hospitalization and arrival Glasgow values for example to determinate the mortality rate.


Nazah CHERIF MOHAMAD YOUSSEF, Thays TABORDA DAMAS (curitiba, Brazil)
08:30 - 17:40 #11886 - Asthma- a serious disease of our time?
Asthma- a serious disease of our time?

INTRODUCTION

Bronchial asthma is currently one of the most common diseases worldwide, with over 30 million affected people in Europe alone.

This study aims to highlight the evolution of the number of patients with asthma in the last three years, and the existence of many associated pathologies that may be an impediment to appropriate treatment.

 

MATERIAL AND METHOD

We conducted a retrospective observational study on a total of 190,864 patients presented at the Emergency Room of Sibiu County Emergency Clinical Hospital with the following annual distribution: 62,804 (32.9%) - 2014, 64,023 (33.54% ) - 2015, 64.037 (33.5%) - 2016.

RESULTS

In the study period, of the total of 190,864 patients presenting with UPU-SMURD Sibiu, 418 (0.22%) were diagnosed with asthma, with the following yearly distribution: 182 (43.54%) in 2014, 145 , 69%) in 2015 and 91 (21.77%) in 2016.

The monthly distribution of patients diagnosed with asthma is the following: January - 49 (11.72%), February - 54 (12.92%), March - 29 (6.94%), April - 35 (8.37% ), June - 37 (8.85%), July - 17 (4.07%), August - 29 (6.94%), September - 33 (7.90%), October - December - 32 (7.66%).

204 (48.80%) of patients diagnosed with asthma during the study had associated pathology as follows: 92 (22.19%) - 2014, 74 (17.66%) - 2015, 38 (9.06% 2016.

127 (30.38%) of patients required hospitalization, thus in 2014 - 59 (32.2%), 2015 - 48 (33.1%), and 2016 - 20 (21.97%).

CONCLUSIONS

Patients diagnosed with asthma represent 0.22% of all patients who presented themselves during the study at UPU-SMURD Sibiu.

During the study, there is a tendency to decrease the number of patients with asthma present at Sibiu Emergency Room.

The manifestations of the bronchial asthma are more frequent in January, February and lower in July.

Almost half (48.80%) of patients with asthma have associated pathology.

Almost one-third (30.38%) of them needed hospitalization.


Virgiliu Cezar BOLOGA, Ovidiu BITERE (Sibiu, Romania)
08:30 - 17:40 #10462 - Atraumatic back pain with paraplegia- An unusual case of spinal abscess.
Atraumatic back pain with paraplegia- An unusual case of spinal abscess.

Back pain is one of the commonest presentation to the Emergency Department and is a leading cause of days of work in the world.A large majority of this is related to traumatic injuries.

We will try and describe a case about a 67 year old female who presented to the Emergency Department with a 3 month history of atraumatic lower back pain and gradual loss of the ability to walk.We will try and describe the various possible differential diagnosis and then go onto to describe the vaious investigative modalites used for this patient.

This was an unusual case whereby the patient had a spinal abscess with no obvious causative reasons and we will describe how this was treated at our facility


Omar GHAZANFAR (Abu Dhabi, United Arab Emirates), Saleh FARES
08:30 - 17:40 #11883 - ATRIAL FIBRILLATION: ANTIARRHYTHMIC TREATMENT TO HIGH IN PATIENTS WITHOUT ATRIAL FIBRILLATION BACKGROUND, DISCHARGED IN SINUSAL RHYTHM. CORRELATION WITH CLINIC. INTRODUCTION: Treatment to high of patients without history of atrial fibrillation (AF) who is.
ATRIAL FIBRILLATION: ANTIARRHYTHMIC TREATMENT TO HIGH IN PATIENTS WITHOUT ATRIAL FIBRILLATION BACKGROUND, DISCHARGED IN SINUSAL RHYTHM. CORRELATION WITH CLINIC. INTRODUCTION: Treatment to high of patients without history of atrial fibrillation (AF) who is.

INTRODUCTION:

The most frequent arrhythmia in an Emergency Department (ED) is atrial fibrillation (AF). It is important to observe how these patients are managed at their exit from the ED.

OBJECTIVE:

To know the variables that influence the decision of discharge or admission of the patients with diagnosis of AF in the ED.

MATERIAL AND METHODS:

A retrospective, descriptive, observational study to rewiev the medical histories, collecting 762 patients diagnosed with AF in the period from 1st October  2012 to 30th December 2013 in the ED of Hospital General Universitario Reina Sofía in Murcia (Spain). Studied variables: patient disposition (discharge, home, consultation), length of hospital stay [less than 48 hours (<48h), more than 48 hours (> 48h), undetermined], history of AF, referral to cardiology, anticoagulation at discharge and if they had AF or sinus rhythm (SR) before leaving the SU. For statistical analysis: ISBN® SPSS.

RESULTS:

Of the 762 patients diagnosed with AF, 70.99% were discharged and 23.62% were admitted.

Of patients discharges, 54.52% were in RS, of these, more than 92% had a clinic of <48h of evolution. In FA, 45.28% of the patients went home, 13 of them, 46% had no previous history of AF, anticoagulated to 85.42% and referred 50% to cardiology consultations.

Of the patients admitted to hospital, 22.22% were hospitalized in sinus rhythm, of these, in 65.0% the length of hospital stay was <48h. In the AF, 74.44% were admitted, with a symptomatology duration of one third for each group of this variable .

CONCLUSION:

Most patients with AF are discharged directly home, half of them in SR, with 90% having a duration of symptoms <48h, so it is deduced that intervention in ED is effective in a high percentage.

A 13.46% without history of AF are discharged in AF, with anticoagulants being more than 85%.

More than 22% were admitted in RS, where 65% had a duration of <48 hours, deducing that there are other factors that are influencing the decision of admission and requires further study.


Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Fernandez-Camacho DANAE, Blanca DE LA VILLA ZAMORA, Nuria RODRIGUEZ GARCIA, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain)
08:30 - 17:40 #11856 - Atrial fibrillation: patients with structural heart disease, efficacy of pharmacological cardioversion and antiarrhythmics used in an emergency department.
Atrial fibrillation: patients with structural heart disease, efficacy of pharmacological cardioversion and antiarrhythmics used in an emergency department.

INTRODUCTION:

Atrial fibrillation is a common reason for consultation in the Emergency Services, requiring rapid and effective treatment, especially in cases involving hemodynamic instability, taking into account specific situations such as structural heart disease.

OBJECTIVE:

To evaluate in patients with structural heart disease who needed control to sinus rhythm those who underwent pharmacological cardioversion, efficacy and type of antiarrhythmic drugs used.

MATERIAL OR PATIENTS AND METHOD:

A descriptive, observational, retrospective study in the Emergency Department of the Reina Sofía University General Hospital of Murcia, which serves a population of 200,000 inhabitants and 275 urgencies / day in which all patients with a diagnosis of Atrial Fibrillation (AF) Between October 1, 2012 and December 30, 2013, who had previous structural cardiopathy measured by previous echocardiography up to 2 years previously meeting the inclusion criteria 762 patients.

Variables to study: presence of structural heart disease, pharmacological cardioversion (FCV) performed, efficacy of FVC, antiarrhythmic drug used.

RESULTS:

During the years 2012 and 2013, 762 patients were diagnosed with AF, of whom 31.76% had structural heart disease, 38.4% had hypertrophic heart disease, 35.95% had valvular heart disease, and in one 16.94% ischemic. Of the total percentage of structural heart defects, 16.94% of the patients had a rhythm control, 39.02% of which was effective in 75% of the cases. Of the same, 58.33% were treated with Amiodarone, 16.67% with Flecainide and 16.67% with Vernakalant.

CONCLUSION:

- In approximately 50% of patients with structural heart disease treated with FVC the antiarrhythmics of choice was Amiodarone in line with clinical practice guidelines.

- Most previous echocardiographies showed Hypertrophic and Valvular Cardiopathies as shown in the literature.

- Some patients were treated with Vernakalant as an alternative to Amiodarone for FCV in patients with AF as they support clinical practice guidelines in patients with mild HF (NYHA I-II), including patients with ischemic heart disease, provided they do not Hypotension or severe aortic stenosis.


Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Danae FERNANDEZ-CAMACHO, Blanca DE LA VILLA ZAMORA, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain), Cesar CINESI GOMEZ
08:30 - 17:40 #11255 - ATTITUDES AND OPPORTUNITIES FOR CONTINUOUS EDUCATION OF NURSES from the National Cardiological Hospital - Sofia.
ATTITUDES AND OPPORTUNITIES FOR CONTINUOUS EDUCATION OF NURSES from the National Cardiological Hospital - Sofia.

Eighty nurses working in Emergency Room, ICU, Intensive Neurological Department, Cardiac and Vascular surgery were anonymously polled.

The survey was conducted between 01.10and 31.12.2016 at the work place.

 

  1. Aim

To examine attitudes and opportunities for continuous education and professional development for nurses at the National Cardiological Hospital - Sofia.

 

  1. Methods

Database research- Documents and statistical data of the National Cardiological Hospital – Sofia were examined.

Monitoring - Observation of nurses working in the Emergency Room in the course of three months.

Survey methodology - Questionnaire consisting of 18 questions.

 

  1. Results

 

20% of nurses who took part in the survey are aged 30 to 40 years, 22% - 40 to 50 years, 32% - 50 to 60 years, and 6% are over 60 years old.

10% of respondents have secondary education, 28% have a college education, 30% have undergraduate education and 12 % have master's education.

68% of the medical professionals consider it necessary to continue their education.

34% of nurses wish to continue their education in higher educational degree, 45% seek to participate in training and other vocational courses, 8% wantto participate in research projects and 13% wish to further their education on their own.

82% of surveyed nurses statethat they have participated in training courses before.

78% of nurses explicitly state that they are willing to re-engage in various post-graduate courses.

25% of respondents were met with understanding and support from their superior in their desire to improve their skills, 55% weren’t met with support and understanding, and 20 percent only had partial support from their superiors.

15% of nurses responded that they would like to develop skills in the field of research and to pursue a doctoral degree, 64% have no desire for scientific work, while 31% are undecided.

 

  1. Conclusion

A large percent of nurses at the National Cardiological Hospital - more than 50% -have the desire and opportunity tocontinue their education and increase their qualifications. Most of them have attended post-graduate courses.

Surprisingly a lot of the questioned medical professionals want to participate in courses focusing on improvement of communication skills for working with rude and aggressive patients.Frequent attacks on medical teams are well known and are becoming part of everyday life for nurses and doctors.Therefore emergency care professionals should have to pass through such courses periodically.

Another conclusion of the study is that nurses associate receiving additional training and skills with higher pay.

Continuous training of medical professionals helps them to perform their tasks more accurately and to fully realize their capabilities. Improving staff qualification is the main factor that ensures continuous advancement of health care efforts.

 


Valentina ATANASSOVA (Sofia, Bulgaria)
08:30 - 17:40 #11840 - Attitudes, behaviors and nursing interventions in extreme situations.
Attitudes, behaviors and nursing interventions in extreme situations.

Introduction:

In Romania there is a shortage of healthcare professionals who provide care to patients in need. Migration of health personnel has led to situations that require a workforce management adapted to new requirements.

 Objectives:  Romania's accession to the EU has had a positive result on the quality of nursing provided by nurses. The new socio-professional offered to conduct the profession led to the development of nursing Romanian to new areas: scientific research, psycho-pedagogical training, continuing medical education.Through this work I intend to stress the importance of nursing research results in developing the nursing profession in extreme situations experienced in medical practice.

Material and method: Descriptive transversal study conducted in the North East region Romanian of investigation used as a method of quantitative research in the period 1 March to 30 April 2017. The instrument is the questionnaire applied research nurses. It comprises 10 factual questions, closed questions with pre-coded answer open questions with answers and free. The sample includes a total of 357 participants. Study data were statistically analyzed whit program Microsoft Office Excel 2007 .

Results:  In the NE of Romania there are 164 health units representing 12.07% of all health units in Romania in public ownership. Some hospitals  in poor condition with outdated technical equipment and human resources (56.88%) presents favorable conditions for the emergence low situations. Supervision and care of large numbers of patients causes conflict situations (64.51%), complaints of patients that have an impact physically, mentally and emotionally on the nurse (76.75%). Limit situations in medical practice management was performed by the entire medical team (69.19%). The nurse has an important role in managing critical situations involving the elaboration of the practice. Health education of patients represents a gain in nurse-patient relationship with a positive influence on the quality of nursing( 66.95%). 

Conclusion:

Awareness campaign about the effect on the quality of nursing limit is achieved by developing good practice guides and courses of prevention and management situations. 

Enhancing medical education of the population through health promotion actions and the introduction of health education as a subject in schools.

Involving government policymakers towards equipping the health units and medical personnel deficit reduction can reduce the occurrence of situations.

Bibliografy:

1. http://www.mdrl.ro;

2. Arch Pediatr. 2010 December; 17 (12): 1696- 708. The alliance of the parent, child and the nurse to challenge medical error;

3. Int J Nurse Stud. 2016 Jan; 53: 95-104. Distress working on dementia wards - A threat to compassionate that: A Grounded Theory study. 


Coca-Stela CRISMARU (BOTOSANI, Romania)
08:30 - 17:40 #11158 - Atypical cases of acute coronary syndrome.
Atypical cases of acute coronary syndrome.

Background: Acute coronary syndrome (ACS) includes all clinical syndromes occurring with acute myocardial ischemia. The pain in ACS is difficult to assess and can be misleading because its subjectivity. Depending on the ECG changes ACS can be divided to ST - elevation (STEMI) and non–ST- elevation (NSTEMI) myocardial infarction. About 30% of all heart attacks are NSTEMI. Changes in biomarkers of myocardial ischemia depend on how much time has passed, as well as the patient’s comorbidity and it can give false-positive or negative results.

Methods: Analysis of 2 cases of atypical ACS

Results: I.B.K. man at the age of 57 is admitted to the ER 12 hours after he was awakened by severe pain in the left shoulder and neck, which lasted 2 hours and decreased after intake of Metamizole 500mg. Accompanying diseases: hypertension, dyslipidemia, IHD triple-vessel disease 2012 (PCI D2, PCI+ x2LAD, PTCA D2). Six months ago – CPET interrupted due to hypertensive crisis without ECG changes. Intake of medicines stopped 6 months ago. Status: hemodynamically stable, ECG - discrete depression of the ST segment in V4-V5; Vesicular breath sounds bilaterally; Abdomen – soft, non-painful with preserved peristalsis; Limbs - no swelling. Laboratory - TrI 28,86; SCAG - calcification of coronary arteries, trunk of LCA - eccentric calcified plaque in the distal segment without stenosis; LAD artery - open stents. D1 – restored blood flow after PTCA, OM2 80-85% stenosis. RCA - dominant artery with long significant stenosis 85-90% in the medial segment. PCI of D2 and RCA.

S.S.D. man at the age of 55 is admitted to the ER 14 hours after in the night he had pulsing chest pain after exercise and consumption of alcohol. In the morning the pain was stronger. The patient was examined by cardiologist and referred for consultation in the emergency room. In ER he complains from tightness in the chest. Comorbidities - not reported. Status- hemodynamically stable. ECG - discrete ST- depression in lateral leads; Vesicular breath sounds bilaterally; Abdomen – soft, non-painful with preserved peristalsis; Limbs without swelling; Chest X-ray - suspected infiltrative shadow in the right apical area. Laboratory - TrI 6,69. SCAG - chronic occlusion of RCA with collateral filling of LAD and subtotal occlusion of OM1. PCI + 2xDES OM1.

Discussion: It is difficult to diagnose ACS in ER because of lack of medical records and history, misinformation from patient and relatives, exaggerated or neglected complaints, lack of time for thorough examination. Diagnosing ACS must be a dynamic assessment of the presenting symptoms and ECG changes; assessment of the co-morbidity and risk factors; evaluation of lab results. Assessing these factors separately could be misleading.


Siyana GEORGIEVA, Siyana GEORGIEVA (Sofia, Bulgaria), Desislava KATELIEVA
08:30 - 17:40 #11189 - Atypical stroke and bizarre bubbles in the ED …Think of decompression illness!
Atypical stroke and bizarre bubbles in the ED …Think of decompression illness!

Introduction :

Recreational scuba diving has become a popular activity in the past 30 years. Although divers are concentrated along coastal regions, many others dive in inland lakes, quarries and reservoirs, or pit dive. Emergency Physicians may see patients with non-specific complaints and need to think to dive-related accidents. A new dive center with a scuba diving pit dive is in place since 6 years training more than 500 divers every weekend. We present 6 cases of patient’s visits in our ED (43,000 visits/year) with non-specific disorders and unusual clinic presentations.

Case Report

Case N°1: Male, 50 y-o, visits the ED with a non-traumatic tendinopathy on his left ankle. A second visit 48h later diagnose a Decompression illness (DCI)

Case N°2 : Female 40 y-o, no medical history, activation the ED Team Stroke for a sudden weakness in her right leg. MRI was normal. Diagnosis of DCI  

Case N°3: Male 53 yo, suspicious of Transient ischemic attacks (TIA) accompanied by nonfocal symptoms like paresthesia on his lips since 24h. DCI (bend) accident was confirmed.

Case N° 4: Male 51 yo, suspicious of ischemic stroke after a 25 minutes dive at 20 meters depth with a “yo-yo diving”. MRI was normal

Case N° 5: Male 37 yo, no medical history, weakness and paresthesia on his left elbow 24h after a 20m dive.

Case N°6 : Female 49 yo, sudden hypoesthesia of left leg 4 hours after her 18m dive. MRI normal.

The majority of disorders are presenting during the first 24 hours after the dive. We searched for nonfocal symptoms like decreased consciousness, amnesia, non-rotatory dizziness, and paresthesia and search for DCI linked to patient’s dives. Three patients with neurologic disorders (case N° 2 ,4,6) went to the hyperbaric recompression chamber in the first hours after their dives, with a complete recovery of the symptoms.

 

Discussion:

The Divers Alert Network reports 1,000 divers are treated with recompression therapy for severe dive-related complications with an average rate of 90 fatalities per year. In France, 350 related-dive accidents happen every year. Patients are male (2/3) mean age 45 y-o, 12 % are beginners and 45% good experience in scuba diving. The majority (98%) of dive accidents are along coastal regions (sea, lake), 2% in pools. Risks factors of DCI are related to the maximum depth of the dive: 5-25m (30,5%); 25-40m (47,5%); 40-60m (17%); >60m(1,7%). According to literature the risk of DCI or arterial gas embolism is 2 for 10,000 dives: 66 % spine accidents, 23 % strokes 8 % vestibular 3 % articular events. International scuba diving guidelines provide instructions to all divers and first aid recommendations to first responders, paramedics and emergency physicians for the diagnostics and treatment of diving accidents with therapeutic hyperbaric chambers recommendations.

Conclusions: Diagnostic of DCI are not easy when symptoms are unusual 24 h after a scuba diving exercises particularly when the ED is not familiar with specific procedures. Procedures may include early detection of DCI and rapid transport to recompression hyperbaric center.


Eric REVUE (Paris), Soufia EL GHANI, Alexandre HENNIART, Edith JEANNE, Stephanie LEGROS
08:30 - 17:40 #10855 - Audit cycle of head CT scans for trauma based on NICE guidelines in a DGH A+E.
Audit cycle of head CT scans for trauma based on NICE guidelines in a DGH A+E.

Objectives: Initially set out to test concordance of imaging requests to NICE guidelines. It became clear that succinct histories on requests were being replaced with buzz words as per NICE guidelines and very little else. Patients were followed to see outcome of imaging.

Method: 100 consecutive head CTs for head injury in adults only. First cycle November 2015, re-audit December 2016.

Results: 98% then 100% concordance with NICE guidelines respectively. Paucity of clinical indications or history other than those words found in NICE recommendations. First audit 13 patients had significant results; re-audit n=6. Of this second cohort, only one patient required further intervention.

Discussion: Many studies have shown a significant percentage increase in CT scans performed after introduction of NICE guidelines for head trauma. This has not led to the expected reduction in patient length of stay, nor has it been shown to significantly change management or reduce costs. In our experience it has led to an over-reliance on guidelines over clinical judgement, a decrease in information used to reason with radiologists and no significant benefit to patient care. We suggest to our own doctors to triumph their clinical judgement and use the guidance as just that, rather than a ‘golden ticket’ to a CT scan.


Josh HOWKINS, Henna SATTAR, Jean SUKUMAR (Carmarthen, United Kingdom), Charles NGOMA
08:30 - 17:40 #11269 - Audit regarding the patient’s journey from ACB to ITU admission via ED.
Audit regarding the patient’s journey from ACB to ITU admission via ED.

Objectives

The objective of this study was to explore the outcome of patients admitted to ACB (Acute Care Bay, Medical HDU) from ED (Emergency Department) who required further ICU(Intensive Care Unit) admission.

Methods

We conducted a retrospective study for 1 year period 01/01/2016-31/12/2016 for 54 patients admitted from ED initially to ACB who required ITU admission afterwards.

Results

The patient’s age were:14.81% of 16-34 years old;18.51% of 35-54 years old;42.59% of 55-74 years old;24.07% of 75-95 years old.

The patient’s functional status was:83.33% independent;3.69% using a stick;7.41% using a frame;3.69% using a wheelchair and 1.85 % requiring full daily care and being morbid obese respectively.

In ED 16.66%cases were reviewed by solely a junior doctor,whilst 27.77% cases were reviewed by solely a senior doctor and 40.74% cases were  reviewed by a junior doctor&senior . 

Following referral to ICU from ED 20.37%cases were reviewed by ICU team within ED from which 5.55% were  declined;1.85%cases were discussed with ICU  over the phone and declined. For 77.77% cases ICU contact wasn't recorded in ED notes.

In ED-14.81%cases were reviewed by ACB team12.96%cases were discussed with ACB registrar over the phone and for 72.22% cases the ACB contact wasn't documented in ED notes.

The length of stay on ACB was:less than 14 hours for 31.48% patients:15 hours-1 day for 42.59% patients;1-2 days for 9.25% patients;2-3 days for 3.70% patients;3-6 days for 7.40% patients;6-10 days for 3.70% patients. The interventions performed on ACB were NIV for 7.40% patients and CPAP for 18.51% patients.

The ICU length of stay was:less than 1 day for 12.96% patients;1-5 days for 51.85% patients;5-10 days for 14.81% patients;10-20 days for 12.96%  patients;20 days-1 month for 3.70% patients and 1-3 months for 3.70% patients.The ICU admitted patients received  interventions as:invasive ventilation-50% patients from which 11.11% patients required tracheostomy;CPAP-12.96% patients;haemofiltration-24.07% patients; Noradrenaline infusion-37.037% patients;Noradrenaline and Vasopressin infusion-1.85% patients;Adrenaline infusion-3.70% patients;Potassium infusion-11.11% patients.The ITU outcome was:68.51% patients were discharged alive and 31.49% patients died.

Conclusions

68.52% cases were reviewed by ED senior.Whilst only 14.81% patients were reviewed by ACB registrar in ED and only 20.37% were reviewed by ITU registrar in ED.Documentation couldn't be found in more than 70% of cases. All this aspects will require further improvement.

74.07%cases had a length of stay on ACB for less than 1 day before being transferred to ICU.

The average admission on ICU was 1-5 days for 51.85% patients and ICU outcome death was 31.49% patients.

The aspects highlighted above including early senior input & documentation within medical notes will require improvement;a meeting between ICU, ACB and ED senior team members to agree a more seamless transfer process and earlier patient reviews will be organized.

 

 

 


Dr Nicoleta CRETU (Leicester, United Kingdom), Neeta PATEL
08:30 - 17:40 #11477 - Audit regarding the patient’s journey from ACB to ITU admission via ED.
Audit regarding the patient’s journey from ACB to ITU admission via ED.

Objectives

The objective of this study was to explore the outcome of patients admitted to ACB (Acute Care Bay, Medical HDU) from ED (Emergency Department) who required further ICU(Intensive Care Unit) admission.

Methods

We conducted a retrospective study for 1 year period 01/01/2016-31/12/2016 for 54 patients admitted from ED initially to ACB who required ITU admission afterwards.

Results

The patient’s age were:14.81% of 16-34 years old;18.51% of 35-54 years old;42.59% of 55-74 years old;24.07% of 75-95 years old.

The patient’s functional status was:83.33% independent;3.69% using a stick;7.41% using a frame;3.69% using a wheelchair and 1.85 % requiring full daily care and being morbid obese respectively.

In ED 16.66%cases were reviewed by solely a junior doctor,whilst 27.77% cases were reviewed by solely a senior doctor and 40.74% cases were  reviewed by a junior doctor&senior . 

Following referral to ICU from ED 20.37%cases were reviewed by ICU team within ED from which 5.55% were  declined;1.85%cases were discussed with ICU  over the phone and declined. For 77.77% cases ICU contact wasn't recorded in ED notes.

In ED-14.81%cases were reviewed by ACB team12.96%cases were discussed with ACB registrar over the phone and for 72.22% cases the ACB contact wasn't documented in ED notes.

The length of stay on ACB was:less than 14 hours for 31.48% patients:15 hours-1 day for 42.59% patients;1-2 days for 9.25% patients;2-3 days for 3.70% patients;3-6 days for 7.40% patients;6-10 days for 3.70% patients. The interventions performed on ACB were NIV for 7.40% patients and CPAP for 18.51% patients.

The ICU length of stay was:less than 1 day for 12.96% patients;1-5 days for 51.85% patients;5-10 days for 14.81% patients;10-20 days for 12.96%  patients;20 days-1 month for 3.70% patients and 1-3 months for 3.70% patients.The ICU admitted patients received  interventions as:invasive ventilation-50% patients from which 11.11% patients required tracheostomy;CPAP-12.96% patients;haemofiltration-24.07% patients; Noradrenaline infusion-37.037% patients;Noradrenaline and Vasopressin infusion-1.85% patients;Adrenaline infusion-3.70% patients;Potassium infusion-11.11% patients.The ITU outcome was:68.51% patients were discharged alive and 31.49% patients died.

Conclusions

68.52% cases were reviewed by ED senior.Whilst only 14.81% patients were reviewed by ACB registrar in ED and only 20.37% were reviewed by ITU registrar in ED.Documentation couldn't be found in more than 70% of cases. All this aspects will require further improvement.

74.07%cases had a length of stay on ACB for less than 1 day before being transferred to ICU.

The average admission on ICU was 1-5 days for 51.85% patients and ICU outcome death was 31.49% patients.

The aspects highlighted above including early senior input & documentation within medical notes will require improvement;a meeting between ICU, ACB and ED senior team members to agree a more seamless transfer process and earlier patient reviews will be organized.

 


Dr Nicoleta CRETU (Leicester, United Kingdom), Neeta PATEL
08:30 - 17:40 #11766 - Auditing Paediatric Attendance to the Advanced Nurse Practitioner (ANP) Minor Injury Service at Portiuncula University Hospital.
Auditing Paediatric Attendance to the Advanced Nurse Practitioner (ANP) Minor Injury Service at Portiuncula University Hospital.

The Emergency Department (ED) at Portiuncula University Hospital currently has 2 Advanced Nurse Practitioners providing a 5 day a week 8am-6pm minor injury service integrated with a full 24 hour Emergency Service. 2,685 patients were seen by ANP’s in 2016. The ANP service has made a significant impact on patient waiting times, patient satisfaction and confidence. ANP’s clinical remit is to focus on minor injuries in adults and children over the age of 4 years and under the age of 16 years.

The study analysed attendances to the ANP service by children between the ages of 0 to 16 years over a period of 12 months in 2016. The aim was to identify the prevalence of minor injury types in smaller children and strategies to improve service delivery to this cohort. The age of the patients, type of injury, waiting times and patient disposals/referrals were recorded to a data sheet.

During the 12 month audit period 506 new cases received treatment. This was reflective of 19% of total patients seen by ANP’s (N=2,685) and 7% of total paediatric ED attendance (N=7,094). There was no major disparity in the timeliness of the service in comparison to the adults with the average check in to be seen by ANP (10 minutes) and check in to discharge 1hr 19 mins. The most common age groups were 13 to 16 years: 50% (N=255) and 5 to 12 years: 39% (N=197).The 0 to 4 years age group (currently shared care with ED Doctors) accounted for 11% (N=54).  Below elbow injuries (N=113) were more common in the 13 to 16 years age group whilst wounds (N=16), burns/scalds (N=6) and elbow injuries (N=9) were more common in the 0 to 4 year age groups. 71% of patients were treated completely by the ANP ED service while orthopaedic and plastics referrals were required by 27% (N= 137) and 2% (N=8) respectively.

Paediatric attendances account for a significant portion of minor injury attendances. Paediatric attendances often pose greater challenges in terms of examination, communication and treatment. There appears to be a number of patterns in terms of age related injuries but these may not be generalisable as the figures for the 0 to 4 years (currently outside the ANP scope of practice) would not be representative of overall injury attendance for this age group. An increase in upper limb injuries in older children most likely reflects sports related in particular hurling, however more investigation is required. Minor wounds, burns/scalds, and elbow injuries specifically pulled elbow in age groups younger than four years are of interest in terms of development of local policies to allow for expansion of scope of practice to provide autonomous service in these areas.


Enda JENNINGS (Galway, Ireland), Kiren GOVENDER, Aidan FALLON
08:30 - 17:40 #11178 - Automated External Defibrillator (AED) - use on public places in Slovakia.
Automated External Defibrillator (AED) - use on public places in Slovakia.

Automated External Defibrillator (AED) - use on public places in Slovakia. 

Abstract

About 23% sudden cardiac arrest (SCA) have shockable rhythm. Defibrillation within 3-5 min of collapse can produce survival rates as high as 50-70%. Early defibrillation can not be achieved through Emergency Medical Service, because average arrival time on scene in Slovakia is 11 min for crew with physician and 12.38 min for crew with paramedic. Early defibrillation can be achieved by public access or onsite AEDs.

Situation about AEDs in Slovakia is described. Poster presents expected AEDs, their location and use. Authors point to fact, that there are no binding obligation for registration of purchased AED and its localization. Central register of AEDs does not exist. Surrounding European countries have registers of AEDs and projects of early defibrillation with good outcomes. Analyse shows that defibrillation through AED did not run regularly in Slovakia, few case reports are illustrated. Therefore urgent priority is established the national register of AEDs. Emergency Dispatch Center should coordinate and evaluate use of AEDs, they have an advantage because of authority on whole Slovak area.

Unknow is number (estimate approximately about 600 AEDs per 5,4 mil. inhabitants), exact localization and owner of AED, so authors suggest:

  1. Obligatory register of purchased AEDs by law
  2. Establish a central register of AEDs (place, type, brand, phone contact, public access AEDs or mobile AEDs and each use) connected to Emergency Dispatch Center of Slovak Republic.
  3. Gain approvals for public use also in surroundings of  owning institution.
  4. 4.      Optimize an existed placed AEDs. Placing AEDs in area of most effective use.
  5. Ensure periodic control and revision of AEDs
  6. Create a network of first responders and ensure their training
  7. Train laypersons in basic life support and use an AED
  8. Support and disseminate AEDs use by laypersons.
  9. Establish serious research and support

 

Key words: sudden cardiac arrest, early defibrillation, automated external defibrillator, register of AED.                                                    


Tana BULIKOVA (Bratislava, Slovakia), Michal ILAVSKY, Viliam DOBIAS
08:30 - 17:40 #10917 - Axillary vein cannulation for central venous access in critical care.
Axillary vein cannulation for central venous access in critical care.

Purpose: The central veins that are usually cannulated are the jugular, subclavian and femoral. As we know ultrasound guidance can reduce complication rates and increase the success of cannulation. We present a case of ultrasound-guided axillary vein placement catheter by Emergency Physicians. This approach is not widely used among emergency physicians. We set an objective to spread this technique among emergency physicians because of its safety features for the patient.

Material & Methods: a patient addicted to parenteral drugs, was admitted to the ER in septic shock condition.

Results: 52 year old woman addicted to parenteral drugs, stage C3 HIV with 2 weeks duration fever. On arrival had malaise, hypotensive, febrile, tachycardic... it was not possible to catheterize a peripheral vein we performed a central line cannulation: ultrasound-guided infraclavicular axillary vein. Less arterio-venous overlap and a greater distance between artery and vein and from vein to rib cage should provide an increased margin of safety for central venous cannulation. We will describe step by step, accompanied by images, the steps necessary to achieve infraclavicular axillary vein cannulation.

Conclusion: The ultrasound-guided axillary approach offers a number of potential advantages over others central line cannulation. The anatomy favours ultrasound guidance and less complications. Manual compression of the axillary artery or surgical access is possible if arterial damage is caused. The puncture site is further away from potential sources of infection in patients with tracheostomy, central chest wall burns or sternotomy wounds. Once mastered, this is a safe, useful, and reliable technique for central venous access, so the axillary vein is an alternative for central venous cannulation, as can be seen in the case presented, an effective alternative to US-guided IJV and SCV cannulation.


Margarita ALGABA MONTES (Sevilla, Spain), Alberto Ángel OVIEDO GARCÍA, Francisco LUQUE SÁNCHEZ
08:30 - 17:40 #11294 - Baby’s way out.
Baby’s way out.

Introduction

Heterotopic pregnancy (HP) is diagnosed in the presence of simultaneous gestations at two or more implantation sites. It was first reported in the year 1708 as an autopsy finding. Its occurrence is rare in spontaneous conception with an incidence of 1:30,000, while in assisted reproductive techniques (ART), the incidence is found to be as high as 1%. We report a case of HP in a natural conception cycle that presented with tubal rupture.

Case presentation

— A 33 years old female presents to our Emergency department at 4:00 am with complaints of lower abdominal pain since 7-8 hours, nausea and 3 episodes of vomiting in that duration. She also complains of difficulty in passing urine and pain while passing stools. She was 6 weeks pregnant after which she experienced PV bleeding and was diagnosed as spontaneous abortion. Dilatation and curettage was done with uneventful post procedure and discharge of the patient. After a week she presented to our ED with above complaints. On general examination she was pale and alert but distressed with pain with pulse rate of 90/min and Blood pressure of 90/50mm Hg. Abdominal examination revealed diffuse, lower abdominal tenderness with significant guarding and rigidity. After initial resuscitation with intravenous fluids, she was further investigated. Her hemoglobin was 9 gm/dl with white blood count (WBC) of 15,320 and normal platelet count. Urine for HCG (human chorionic gonadotropin) was positive. FAST scan was done and was positive for all 3 views. Transvaginal sonography was done and was suggestive of multiple clots in pelvis predominantly in right adnexa (echogenic without vascularity), hemoperitoneum, and no obvious gestational sac noted. Emergency laprotomy was conducted and removal of all debris along with 1L blood in the peritoneal cavity was done. Post operatively she was given 1 unit of PCV and treated with I/v antibiotics, analgesics and other supportive measures. The post procedure stay remained uneventful and she was discharged in stable hemodynamic condition.


Dr Ketan PATEL (Ahmedabad, India), Anjali PATEL, Rignesh PATEL
08:30 - 17:40 #11182 - Baclofen overdosage: a rising entity – case report.
Baclofen overdosage: a rising entity – case report.

Background

Baclofen is a gamma-aminobutyric-acid-agonist (GABA-agonist) acting on the central nervous system (CNS). It is mainly prescribed to relieve spasticity and muscular rigidity in multiple sclerosis, spinal cord lesions and other diseases of the CNS that might result in muscular spasms. Recent clinical trials have shown that 30 to 300 mg/day oral baclofen can reduce alcohol caving, intake and relapse and it is actually used for alcohol withdrawal syndrome and cocaine addiction. Its use has therefore become increasingly popular, thus resulting in a soaring number of intoxication cases.

Case report:

A 23-year-old female with no previous medical history presented to the emergency department one hour after deliberate oral intake of 300 mg of baclofen. This medication was previously prescribed for her mother. On the initial examination, she was initially fully awake. Blood pressure was 120/60 mmHg, heart rate was 108/min, and temperature was 37.2°C. Respiratory rate was 16/min, pulmonary auscultation without abnormalities in two lung field and pulsed oxygen saturation was 98%. An attempt to perform gastric lavage was unsuccessful due to its poor tolerance by the patient. She was kept under clinical surveillance. Five hours later, she developed tremulations, vomiting, sinus bradycardia and hypotension. Her Glasgow Coma Scale dropped to 8/15. Fluid resuscitation with crystalloid solutions and mechanical ventilation were necessary. The patient was therefore transferred to intensive care unit (ICU) and further laboratory tests were carried out revealing rhabdomyolysis and hypokalemia. Treatment with atropine and 52 hours of mechanical ventilation was undertaken along with antibiotic administration for aspiration pneumonia and potassium supplementation. The outcome was favorable and the patient was discharged four days following ICU admission.

Conclusions:

Although baclofen intoxication cases are being increasingly reported, few studies have worked on setting precise thresholds for the toxicity spectrum of this drug. Lack of guidelines might result in the under-estimation of theoverdosage effects and treatment delays. Continuous ICU monitoring is mandatory in all cases.


Fatma HEBAIEB (Ariana, Tunisia), Ameni SGHAIER, Salah SNOUDA, Moez KADDOUR, Eya HNIA, Raja FADHEL, Abir TAKROUNI, Hassen BEN GHEZELA
08:30 - 17:40 #11146 - Bacteremia related to central venous catheters : An experience of a medical intensive care.
Bacteremia related to central venous catheters : An experience of a medical intensive care.

Introduction

Bacteraemia related to catheters is the association of bacteremia occurring within 48 hours of catheter shrinkage and a significant culture of the catheter (> 1000 cfu / ml) or catheter insertion site culture that registers the same germ.

The objective is to determine the incidence of bacteremia related to catheters (BLC) in a medical resuscitation service, their microbiological profile and the risk factors associated with their occurrence.

 

Patients and methods

 Over a period of one year, spread between January 2015 and December 2015, all patients admitted to intensive care units and subjected to a central venous catheterization of more than 48 hours were included.

The BLC was selected on:

• Cultivation of the end of the catheter withdrawn positive according to BRUN BUISSON method> 103 CFU / ml

• The local and general signs present

The proportions of colonization and BLC were expressed as cumulative incidence (CI) of CLI.

Statistical analysis was performed using the univariate method.

 

Results

 The incidence rate was 6.78% with predominantly female 51.9%.Isolated microorganisms were represented by Gram-negative bacilli in 40.5% of cases, Gram-positive cocci in 35.4% of cases, and yeasts in 5% of cases.

Statistical analysis showed two main risk factors for colonization: prolonged catheterization and absence of systemic antibiotic therapy before catheterization.It is important to note that the lack of information in the medical files concerning the installation of the CVC is a weighing element on the follow-up of its infections indeed a checklist must be used like a memo tool that will make it possible to And to minimize risks related to human hazard.

 Conclusion

 The incidence of BLC was high, requiring reflection by the healthcare team to improve protocols and bundles for the prevention of these nosocomial infections.


Ezzouine HANANE (CASABLANCA, Morocco), Nassiri GHASSAN, Benslama ABDELLATIF
08:30 - 17:40 #11556 - Bartholin's gland abscess in 10 month old girl.
Bartholin's gland abscess in 10 month old girl.

 Bartholin’s gland abscesses are rare in females before puberty we report a case of Bartholin’s gland abscess in 10 month old female child along with review of the literature.

Key words: Bartholin’s gland abscess, children, incision and drainage.


Soumaya BENSLIMAN, Soumaya BENSLIMAN (Doha, Qatar)
08:30 - 17:40 #11894 - Be careful about Hutchinson's sign, Ocular involvement needs care in debilitating patients.
Be careful about Hutchinson's sign, Ocular involvement needs care in debilitating patients.

Herpes zoster(HZ) is common in the elderly. The increased risk for developing Hz is associated with immunosuppression from chemotherapy for malignancy, immunosuppressive diseases such as AIDS, and most commonly with aging related deficiency of cell mediated immunity to varicella zoster virus. In approximately 20% of the cases, virus affects the first division of the trigeminal nerve, producing the characteristic and usually painful zoster rash on the forehead, periorbital area and nose. Hutchinson's sign that nasociliary skin lesions of virus was a powerful predictor of ocular inflammation and corneal denervation in herpes zoster ophthalmicus(HZO).

Our case was a 83 years old debilitated woman who came to our emergency service with a complaint of vesicles on the left side of his forehead and nose, accompanied by severe headache and ocular pain with edema. The physical examination revealed the presence of vesiculobullous lesions with erythema and crusted erosions on the left side of the forehead. Periorbital edema and bulbar conjunctival injection was obvious on her left side. Ophthalmologically, at presentation visual acuity, corneal sensation, detailed slit-lamp examination to detect anterior segment involvement and fundoscopy to detect posterior segment complications of Herpes Zoster Ophthalmicus were carried out in this patient. She was diagnosed with keratitis and iritis. The laboratory examination revealed mild liver dysfunction, mild leucocytosis and elevated levels of C-reactive protein. From these clinical and laboratory findings, she was diagnosed with HZO with iritis. Because of her severe iritis, 7 day intravenous acyclovir following 3 week po valacyclovir was used as treatment.

The reported incidence of visual loss in HZO patients varies widely between 14% and 56% especially higher in immunocompromised patients. Immunocompetant patients receiving antiviral therapy show the best outcomes. Most studies have reported a definite reduction in the occurrence of visual loss with the use of antiviral therapy. The visual outcome was poorer in older patients. This could be attributed to the presence of preexisting senile cataracts. Chronic epithelial lesions can however cause severe visual loss and are often difficult to treat. Persisting loss or reduction of corneal sensation is in important factor in the occurrence of chronic epithelial lesions like neurotrophic keratitis. These patients should be counselled regarding the need for long-term follow up. Nasociliary nerve involvement indicated by the presence of Hutchinson sign was found to be a strong predictor for poor visual outcome and this concurs with other reports. It was also established that increasing rash severity was associated
with poor visual outcome.

Visual outcome in HZO patients treated with antiviral therapy is good. Hutchinson's sign and anterior uveitis were found to be strong predictors for poor visual outcome. Presence of these identified risk factors warrants close monitoring.


Volkan ÜLKER (ISTANBUL, Turkey), Abdullah Cüneyt HOCAGİL, Hilal HOCAGİL
08:30 - 17:40 #11792 - Bedside echocardiography: a noninvasive procedure with the ability to change the outcome of acute myocardial infarction dramatically.
Bedside echocardiography: a noninvasive procedure with the ability to change the outcome of acute myocardial infarction dramatically.

Background: Ischemic heart disease is still the leading cause of death in adults in developed and developing countries. Acute myocardial infarction (AMI) is a serious and dangerous presentation of acute coronary syndromes. AMI is defined as myocardial cell death and necrosis due to sever and prolonged obstruction in myocardial blood flow. AMI leads to several complications. These can be classified as two subgroups: electrical and mechanical complications.

 Ventricular free wall rupture (VFWR) after AMI is a serious and potentially life threatening mechanical complication. It may occur as early as a few hours after infarction up to 5 days. The clinical presentations of VFWR include prompt death, transient syncope, agitation, acute cardiogenic shock, pleuritic chest pain, recurrent emesis, dyspnea, etc. Risk factors associated with VFWR include advanced age, female sex, first time MI, anterior wall MI, ST elevation or Q wave development on the initial ECG, large infarct size and late or failed PCI. Emergent surgical intervention is the treatment of choice for this complication. Pericardiocentesis is indicated as an immediate temporizing intervention.

Case: A 64 years-old male with HTN and diabetic mellitus presented to emergency department with generalized weakness and drowsiness. He had experienced a syncope attack while walking an hour before coming to ED. On arrival, he was vomiting. He had no chest pain but dyspnea and orthopnea from 3-4 days ago.

VS: PR: 90/min,   BP: 70/50 mmHg (no significant difference between two arms), BS: 180 mg/dL,   SPO2: 89% in room air, RR: 28/min.

Heart sound was muffled with no increased neck veins. Lungs field was clear.

ECG showed an extensive ST-segment elevation MI with anterior, inferior and right side involvement. PCI was considered as a reperfusion therapy. But the patient condition did not change after initial fluid replacement therapy, so a vasopressor was initiated too. The portable CXR revealed a wide mediastinum (10 cm). In search for aortic dissection as a possible cause of these findings, we decided to do a bedside echocardiography in the ED. We found a large pericardial effusion and mild to moderate RV and RA collapse during diastole with no intimal flap or dilated aortic root. After consultation with a cardiologist and a heart surgeon, we decided to transfer the patient immediately to the heart surgery center for possible operation because of relative stability in patient condition. Left ventricular free wall rupture confirmed during cardiac surgery. Ruptured wall was repaired and the patient discharged home after a long time hospitalization.

Conclusion: signs of cardiac tamponade on ECG or echocardiography are suggestive of VFWR in the setting of acute or recent MI. VFWR is fetal, but prompt diagnosis followed by emergent surgery may be lifesaving. Echocardiography is crucial for the prompt diagnosis of this complication and can change the patient outcome dramatically in this sitting.

 


Mehran SOTOODEHNIA, Atefeh ABDOLLAHI (Tehran, Islamic Republic of Iran), Hamideh AKBARI
08:30 - 17:40 #11224 - Bedside ultrasound and acute aortic syndrome in emergency settings.
Bedside ultrasound and acute aortic syndrome in emergency settings.

Purpose: The diagnosis of an aortic dissection by a bedside ultrasound. Aortic dissection is relatively rare, but may occur as a catastrophic condition for the patient's prognosis, so an early diagnosis and treatment is crucial to their survival. We used two systems of classification of this pathology, being the Stanford classification most frequently used in clinical practice: type A dissection, involves the ascending aorta; type B dissection involves the descending aorta or the arch without involvement of the ascending aorta.

 

Material & Methods: We studied the diagnosis of an aortic dissection type B of Stanford by a bedside ultrasound performed by emergency physician. We have an ultrasound-Sonosite M-Turbo, P21 probe of between 1 and 5 MHz, with and echocardiography software.

 

Results: A 76 years old male, admitted to the emergency room because he suffers intense, transfixing, oppressive central chest pain radiating to the back. He had normal vital signs. Analysis revealed a D-dimer 6222 µg/ml, with normal cardiac enzymes and electrocardiogram, but showing an aortic elongation mediastinal widening on chest radiograph, so the emergency physician performed an ultrasound scan that showed a double light in the abdominal aorta, until iliac. A thoracoabdominal computed tomographic scan was immediately performed with contrast confirmed type B aortic dissection, from the left subclavian to the iliac bifurcation, with false light in a posterior position, without involvement of supra-aortic arteries and visceral branches. The patient was admitted to the Intensive Care Unit, opting for traditional treatment, was discharged  without later complications.

Conclusions: The ultrasound has become in the last few years an indispensable tool for the emergency physician, and there is broad international supporting literature that recommends and requires that us, all the emergency physicians, use ultrasound for the benefit of our patients; but its use is not infallible, so performing the technique and interpretation by not medical experts, must be supervised by others with more experience to guide them so possible diagnostic errors are avoided.


Francisco LUQUE SÁNCHEZ (Seville, Spain), Alberto Ángel OVIEDO-GARCÍA, Margarita ALGABA-MONTES
08:30 - 17:40 #10928 - Bedside ultrasound and portal venous gas diagnosis in emergency department.
Bedside ultrasound and portal venous gas diagnosis in emergency department.

Purpose: Intestinal pneumatosis (IP) defined as the presence of gas within the bowel wall and the presence of gas in the portomesenteric vein complex, a rare clinical condition that are typically associated with intestinal ischemia (II) and a fatal outcome. We present a case of IP, diagnosed at emergency room, through the use of US scanning by emergency physicians (EP).

Material & Methods: a patient with abdominal pain, with a final diagnosis of a IP assessing US, performed by EP.

Results: 82 year old woman, active and independent, who came to the ER with abdominal pain from 12 hours, which started about 2 hours after dinner. The patient presented malaise, affected by pain, hypotensive and tachycardic. Given the general malaise the patient underwent an abdominal ultrasound scan at the bedside of the patient showed many small echogenic mobile pictures that moved through the portal vein and its branches, and in the left hepatic lobe level we saw also multiple linear echogenic pictures in the portal branches with posterior acoustic shadows. Suspecting IP and gas in the abdominal venous complex portomesenteric urgent contrast CT was made, which confirmed the diagnosis.

Conclusion:

CT and US are the most commonly used imaging modalities in patients with acute abdomen and even if CT represents the gold standard in the evaluation of patients with II. However, there are some disadvantages associated with this technique, such as radiation exposure, potential nephrotoxicity and the risk of an allergic reaction to the contrast agents. Thus, not all patients with suspected bowel ischaemia can be subjected to these examinations. Despite its limitations, bedside ultrasound performed by EP could constitutes a good imaging method as first examination in acute settings of suspected mesenteric ischemia.

Ultrasonography by EP, can be a useful tool in cases with serious diseases. Incorporate ultrasound in the ER lowers overall service times, since the EP is more effective, efficient and dynamic management "time-dependent" emergency, providing greater clinical patient safety.


Alberto Ángel OVIEDO GARCÍA (DOS HERMANAS (SEVILLA), Spain), Francisco LUQUE SÁNCHEZ, Margarita ALGABA MONTES
08:30 - 17:40 #10921 - Bedside ultrasound and septic shock patient in emergency settings.
Bedside ultrasound and septic shock patient in emergency settings.

Purpose: Pyonephrosis (PN) is an uncommon disease that is associated with suppurative destruction of the renal parenchyma in adults. Obstruction and upper urinary tract infection play a role in its etiology. Fever, shivering, and flank pain are frequent clinical symptoms. If the pus detected as a result of the investigations is not surgically drained, antibiotics may not be effective. Septic shock and death can occur if the disorder is not treated with urgent surgery. In this context percutaneous open nephrostomy or retrograde ureteral catheter insertion is appropriate, so it is a very serious disease and emergency physicians (EP) have a very important role in early diagnosis to start antibiotic treatment and early referral to surgery. We present a case of septic condition with PN developing due to a distal ureteral stone, diagnosed at ER, through the use of US scanning used by EP

Material & Methods: a patient with fever, right flank pain and septic condition, with a final diagnosis of a calculous PN.

Results: 56 year old male, was admitted to the emergency room by right flank pain and fever. On arrival had malaise, hypotensive, febrile, tachycardic... in septic shock condition. Bedside emergency abdominal US was performed by EP, demonstrating right moderate to severe pelvocaliectasis due to a distal right ureteral stone. The patient was started on empirical antibiotics and a retrograde ureteral internal stents was placed by urologist.

Conclusion: Identifying PN with early obstructive uropathy is clinically important in the emergency department because obstructive urolithiasis is an independent risk factor for inpatient death; so PN  is a life-threatening condition. Emergent bedside ultrasound can do that EP may dramatically increase their ability to identify those patients that need further investigation, consultation and ultimately increase patient safety in emergency department. In the case presented thanks to the implementation of emergency US by the EP came to a prompt diagnosis of the cause of septic shock, with a quickly drainage of the infection site, which it allowed rapid patient recovery.


Margarita ALGABA MONTES (Sevilla, Spain), Alberto Ángel OVIEDO GARCÍA, Francisco LUQUE SÁNCHEZ
08:30 - 17:40 #11811 - Bifascicular block and syncope progressing to complete atrioventricular block : about a case report.
Bifascicular block and syncope progressing to complete atrioventricular block : about a case report.

Bifascicular (BF) block represents a particular form of intraventricular conduction disease.which is associated with a high incidence of progression.In some patients, this form of conduction disease progresse to high degree of atrioventricular ( AV)  block and accompany by syncope.

A 41-year-old man was admitted to the emergency department (ED) because of complete AV block and syncope.Until 4 years earlier, he visited the ED because of suddenloss of consciousness while running.There werw no whitnesses.He regained consciousness spontaneously and there were no postepisodic fatigue or weakness.He was brought to the ED but was discharged without a definitive cause of the syncope, and all relevant tests were negative except ECG showed BF block.

The management of BF block was determinated by the severity of symptoms and the degree of associated AV block.The guidelines recommended that the implantation of pacemakers is indicated in asymptomatic chronic BF block with intermittent third-degree of AV block, and type II segond-degree AV block.Pacing is also indicated in BF block with a markedly prolongated HV interval or syncope not proved to be due to a AV block.Pacing was not recommended in fascicular block without AV block and symptoms.

In summary, patients with BF block and syncope require more clinical attention.These patients had higher incidence of progression into complete AV block.In cases with BF block is symptomatic or associated with high degree AV block, pacemaker therapy is highly effective for the relief of symptoms.


Felicidad YAÑEZ RODRIGUEZ (CALATAYUD, Spain), Ignacio ANDRES BERGARECHE, Martha URDAZ HERNANDEZ, Sergio MUÑOZ JACOBO, Miguel RIVAS JIMENEZ, Marisa CATALAN LADRON
08:30 - 17:40 #11292 - Blunt abdominal trauma complicated by retroperitoneal mycotic abscesses.
Blunt abdominal trauma complicated by retroperitoneal mycotic abscesses.

 Blunt abdominal trauma patients requiring emergency laparotomy represent a challenging category of trauma patients with increased morbidity and mortality usually due to co-existing injuries.

 

A 14 year old patient was transferred to the emergency department, after he had sustained a traffic accident with a motorbike. The mechanism of injury involved high velocity deceleration on a fixed obstacle (wall).

During the initial evaluation, the patient exhibited good neurologic status (GCS:15/15)and ventilation (PO2:95%), Grade 1 schock (BP :105/65, 100 Bpm) as well as fractures of the right femur, the left ulna and radius and dislocation of the right elbow joint.

After the initial resuscitation he underwent emergency CT+IVC of the thorax and abdomen, that revealed a Grade 3 injury to the spleen, a Grade 1 injury to the right lobe of the liver as well as free intraperitoneal air, so emergency laparotomy was undertaken.

Additional findings at laparotomy  were a linear tear of the greater curvature of the stomach, hemoperitoneum due to active bleeding from the splenic injury and copious amount of undigested food in the abdomen. Splenectomy and primary repair of the gastric rupture were performed as well as thorough lavage of the abdomen and drainage through 3 soft tubes. The hepatic injury was managed with hemostatic gauze placement.

Internal fixation of the femur was also performed after 48 hours.

The patient was managed initially in the ICU, where pancreatitis was diagnosed on the 3rd postoperative day, that improved gradually and the patient returned to the surgical ward on the 13th postoperative day.

The patient’s recovery was complicated by spiking fever and cachexia due to early gastric filling and vomiting. Follow up abdominal CT+IVC revealed the presence of large multilocular retroperitoneal abscesses that were managed with CT guided percutaneous drainage of the 2 largest collections that revealed C. Albicans in the cultures.

There was a transient improvement of the patient’s symptoms for 48 hours but resurgence of fever mandated the re-exploration of the abdomen and surgical drainage of the abscesses on the 23rd postoperative day.

The patient displayed impressive recovery after the 2nd operation and was discharged in good condition on the 32nd postoperative day.

The mycotic superinfection of the pancreatic phlegmon severely increased the morbidity and delayed the recovery of this multi-trauma patient.

Surgical drainage of retroperitoneal abscesses is mandatory when conservative measures fail.

 

 


Alexandros PAPADOMICHELAKIS (KATO DARATSO-CHANIA, Greece), Georgios PETRAKIS, Paraskevi KARONA, Athina ANAGNOU, Eleni TSAKIRAKI, Spyridon KAVROCHORIANOS, Emmanouil CHARITAKIS, Aggeliki KOUTSOURAKI, Athanasios KOURAKOS
08:30 - 17:40 #10887 - Blurred vision secondary to Metformin. The importance of adverse effects.
Blurred vision secondary to Metformin. The importance of adverse effects.

CLINICAL HISTORY AND EVOLUTION.

 

A 70-year-old man who goes to the emergency department for a blurred vision of 10 days of evolution in both eyes. Initially, the patient is evaluated by Ophthalmology, which dismisses ocular pathology as the origin of the problem and is referred for evaluation by emergency physicians.

As a history of interest we emphasize that this patient is a diabetic and hypertensive patient and is on treatment with Metformin 850 mg twice daily and also takes Enalapril 5 mg every 24 hours and acidoacetylsalicilico 100 mg a day. After dinner you are given  1 mg alprazolam.

The patient is evaluated in the emergency room where a complete exploration by organs and devices is carried out without any alteration being objectified and without the existence of any neurological focal points.

Complementary tests are required, including blood and urine tests, chest x-ray, electrocardiogram and cranial Tac. Complementary tests are normal and the patient is referred home for follow-up and control by their primary care physician.

Days later the patient returns to the emergency department because symptoms persist and blurred vision is becoming more intense.

Again it is evaluated by ophthalmology on watch and then by the emergency doctor repeating all the complementary tests mentioned above that turn out to be negative again. On this occasion, a consultation is performed with the Neurologist on call who thinks it may be an episode of migraine with aura and prescribes medication for the control of symptoms: Rizatriptan 10 mg and quotes the patient for review in the specific consultation of migraines.

A week later the patient returns to the emergency department because the picture has worsened, at this time the case and all the complementary tests are reviewed again and it is commented on in a clinical session where it is lowered as one of the options the possibility of It was an adverse effect on medication that the patient took.

Metformin withdrawal was decided by improving the ad integrum chart one week later.

 

CONCLUSIONS

Adverse drug events constitute an emerging pathology with a great social and economic impact; However they are not yet assumed in most countries as a priority problem. In order to achieve this reduction, it is necessary that health professionals, scientific societies, agencies and institutions linked to health care and prevention, the pharmaceutical industry and patients themselves become aware of the importance of this problem and acquire the necessary culture to recognize and address targeted measures to reduce this problem.

 


Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO, David NUÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11615 - Brain stem and visual evoked potentials in diagnosis of Central Demyelination in Guillain Barre Syndrome.
Brain stem and visual evoked potentials in diagnosis of Central Demyelination in Guillain Barre Syndrome.

Brain stem and visual evoked potentials in diagnosis of Central Demyelination in

Guillain Barre Syndrome

 

Dr. Geetanjali Sharma, Professor, Department of Physiology, Pt. B.D. Sharma Post-Graduate Institute of Medical Sciences, University of Health Sciences, Rohtak, Haryana, India

 

Aims: Guillain Barre Syndrome (GBS) is an auto-immune mediated demyelination polyradiculo-neuropathy. Clinical features include progressive symmetrical ascending muscle weakness of more than two limbs, areflexia, with or without sensory, autonomic and brainstem abnormalities. The purpose of this study was to determine subclinical neurological changes of CNS with GBS and to establish the presence of central demyelination in GBS.

Study design: a prospective study to find out early central demyelination in clinically diagnosed patients of GBS.

Place and duration of study: Department of Physiology, Pt. B.D. Sharma Post-Graduate Institute of Medical Sciences, University of Health Sciences, Rohtak, Haryana, India between January 2014 to June 2015.

Methodology: The patients were referred the department of Medicine to our department for electro-diagnostic evaluation. The study group comprised of 40 subjects (20 clinically diagnosed GBS patients and 20 healthy individuals) aged between 6-65 years. Brain stem and visual evoked potentials were done in both groups using RMS EMG EP Mark II machine. BAEP parameters included the latebcies of waves I to IV, inter-peak latencies I-III, III-IV & I-V while VEP included latencies of P100 waves.

Results: Statistically significant increase in absolute peak and inter-peak  latency in the GBS group as compared to the control group was noted. Prolongation of latency of P100 wave latency in both the right and left eyes was also recorded in the GBS group.

Conclusion: Results of evoked potentials reflect impairment of auditory and visual pathways probably due to focal demyelination in Schwann cell derived myelin sheaths that cover the extra medullary portion of the auditory nerves and also due to demyelination of optic pathways. Prolonged central conduction time in BAEPS & VEPS suggest the subclinical auditory and optical involvement in GBS. Early detection of the sub-clinical abnormalities is also important as timely intervention reduces morbidity and mortality.

 

 


Geetanjali SHARMA (Rohtak, India)
08:30 - 17:40 #11027 - Breaking the cycle of violence: emergency department staff perceptions of the Navigator programme.
Breaking the cycle of violence: emergency department staff perceptions of the Navigator programme.

Background

The Navigator programme, a novel intervention, was developed in response to the volume of patients presenting to emergency departments (ED) with injury or illness associated with violence, alcohol or drugs. Presentation to the ED is a frequent and recurring event for many patients with chaotic lifestyles and presents a ‘reachable’ moment (1).  Navigator is an opportunistic intervention operating within this moment that aims to reduce future ED presentations. The aim of this preliminary study was to determine the views of the ED staff on the Navigator service.

 

Methods

The study was performed at Glasgow Royal Infirmary. The ED has approximately 95,000 attendances annually with a case mix that reflects its location in an area of high socioeconomic deprivation. We conducted semi-structured interviews with a cross section staff within the ED to determine their views on the impact, benefits and direction of the programme. Interviews were recorded, transcribed and analysed using thematic analysis (2)

 

Results

During the first 12 months of operation Navigators provided support to 209 patients, 143 male and 66 female patients, with an age range of 15-80 years (median age 30 years). The main presenting issues for male patients were alcohol, drugs, violence and homelessness and for female patients were alcohol, drugs and domestic abuse. Seventy-seven patients presented with multiple issues.

 

Staff views on the service centred around three main themes.  Provision of support to patients both within and outside the ED. Secondly, an ability to connect with patients on their own level and to start to address the issues underlying their attendance; the ED staff spoke about their own lack of time. Thirdly, support to stabilise some of the chaos in their lives and a chance to break away from the cycle of violence.

 

Conclusion

We present a model of the Navigator programme describing the characteristics of the service group and ED staff views of the strategies Navigators implemented to achieve meaningful change for those patients. The programme was well received by ED staff and the Navigators were perceived as being a valuable addition to the service provided in the ED. Before consideration is given to further development and dissemination of the project to other tertiary EDs, further evaluation is underway to measure outcomes, impact and efficacy. 

 

References

1. Holdsworth et al (2012). Maximising the role of emergency departments in the prevention of violence: Developing and approach in South London. Public Halth 126: 394-396.

2. Braun V, Clarke V (2006) Using thematic analysis in psychology. Qual Res Psychol 3:77–101

 


Jessica JAMESON, Jessica JAMESON (Glasgow, United Kingdom), David LOWE, Christine GOODALL
08:30 - 17:40 #11637 - Brugada syndrome: A case report.
Brugada syndrome: A case report.

Background:

Brugada syndrome (Bsd) is a rare genetic disease.It causes sudden cardiac death by severe rhythm disorder occurring on a healthy heart. Prognosis is severe in symptomatic patients and is based on the prevention of sudden death by placing an implantable cardioverter-defibrillator (ICD).

 

CASE REPORT:

 

We report the case of a 24 years old man with no medical history who suddenly presented a cardiac arrest. Rescuers started immediately a cardiopulmonary resuscitation (CPR) until the transfer of the patient to the emergency department. After 15mn of CPR the patient had a ventricular fibrillation (VF) 3 successive external electric shock were delivered at an energy of  200 J in biphasic asynchronous mode followed by an intravenous cordarone injection at the dose of 300 mg .A sinus rhythm was achieved with a stable hemodynamic status.

An ECG showed a right bundle branch block with a persistent ST segment elevation suggestive of a type 2 Bsd without abnormalities in the echocardiography as well as the cerebral CT scan and the toxicological analysis .Two days after the patient was extubated with a favorable clinical and biological outcomes .Since then, he was followed up in the cardiology department.However, while waiting for diagnostic confirmation and implementation of an ICD, the patient died with the same clinical presentation. 

Discussion: Bsd is a rare but a fatal disease since it has a serious rhythm complications. A rapid and urgent in hospital medical strategy should be started immediately to prevent these complications and improve the survival of these patients. 

 

 


Asma ALOUI (Tunis, Tunisia), Hana HEDHLI, Wided DEROUICH, Rym HAMED, Imen MEKKI, Rim HAMMAMI, Mohamed KILANI, Chokri HAMOUDA
08:30 - 17:40 #11862 - Buprenorphine abuse resulting in necrotizing fasciitis.
Buprenorphine abuse resulting in necrotizing fasciitis.

Introdcution :

Buprenorphine (Subutex) is a partial mu receptor agonist and κ receptor antagonist which was advocated as oral maintenance treatment for patients with opioid dependence. Although Subutex is safe and effective, parenteral abuse is an emerging phenomenon. The intravenous injection of pulverized buprenorphine tablets may produced various physical complications, such as abscesses, human immunodeficiency virus (HIV) infection, hepatitis B or C infections, respiratory depression, and tricuspid or pulmonary valve endocarditis. Both intravenous and intra-arterial injections of pulverized buprenorphine may cause peripheral limb ischemia.   In this observation we present a case report of patient who presented to the emergency department following complications of Subutex abuse.

Observation :

 A 36-year-old male drug user presented at the emergency department with fever, severe left extremity pain and warmth one week after the local intravenous administration of buprenorphine. On examination, the patient appeared acutely ill and the temperature was 37.7 °C. The thigh was swollen but not erythematous, and was exquisitely painful. Moreover, necrotic area was noticed on the homolateral limb.  On biology, markers of inflammation were rised. Radiography of the inferior limb showed subcutaneous air bubbles. We completed by a computerized tomography wich shows a liquid collection with air bubbles at the edge of the psoas muscle and, with a destruction of the homolateral coxo-femoral joint.  Patient was transferred urgently to the surgery ward.The diagnosis of necrotizing fasciitis was then  confirmed per surgery by explorating fasciectomy with extensive debridement.  Further bacteriologic cultures of necrotic tissues grew  staphylococcus.

Conclusion :

Few reports of Complications arising from buprenorphine abuse in the literature were documented probably because this drug has only been widely available in the last few years. For fear of legal prosecution, patients usually present late, greater public awareness and education regarding the dangers of parenteral abuse of Subutex should also help decrease the incidence of such complications 


Aymen ZOUBLI (Tunis, Tunisia), Hamed RYM, Sarra JOUINI, Imen MEKKI, Ahmed SOUYAH, Maroua MABROUK, Abir WAHABI, Chokri HAMOUDA
08:30 - 17:40 #10892 - Burnout Among emergency nurses.
Burnout Among emergency nurses.

INTRODUCTION
The daily practice of Medicine in the Emergency Department (ED)  involves a lot of challenges. In fact, in a short period of time,  ED workers have to make crucial decisions in order to improve the health of their patients.  These circumstances can lead a burnout syndrome in these professionals.
OBJECTIVE AND METHOD
We present a descriptive study that examined  29 nurses of the Emergency Department of a  public and urban hospital for the presence of burnout. During one week, they could answer a survey divided into two parts. In the first one, age, sex, marital status, time of working and employment situation were tested.  The second one was the Maslach Burnout Inventory (MBI) with its three components -Emotional Exhaustion( EA), depersonalization (DP) and reduced personal accomplishment ( PA)- which is currently widely used.  All of the respondents had worked at least during 6 months in the same workstations.  The participant was considered to meet the study criteria for burnout if they have a "high" score on at least 2 of the three dimensions of MBI.
RESULTS

Twenty-nine surveys were delivered and twenty-eight nurses answered (96.55%) which demonstrates the great interest of these professionals in the problem.
 The average age was  45.93 years  (Rank 34-59),  twenty-two of them were females and six were males.  Nine of them were singles and nineteen had a stable couple. The average time of working was 10.79 years  (Rank 1-30). Finally, fifteen nurses had an indefinite contract and four of them had a temporary contract.

We found high leves in EA in the  32.1% and 42.9% in DP and low leves in 10.7%  in PA.  In 7 of them (25%) we found 2 or 3 pathological subscales. Burnout was more frequent in men, unmarried, under 40 years, with occasional work and with less than 20 years in the current workstation nevertheless there wasn´t  significant difference between groups.
CONCLUSION
The nurses of the Emergency Department show  a moderate  level of burnout.  Administrators should be aware that symptoms of burnout constitute potential precursors of more severe impairment  and should implement  interventions in order to improve the career satisfaction and prevent burnout


Rosario PEINADO CLEMENS, Alvaro MARTIN PÉREZ (Badajoz, Spain), Miguel Angel RUIZ SANZ, Concepción DE VERA GUILLEN
08:30 - 17:40 #11510 - BURNOUT SYNDROME IN EMERGENCY. COGNITIVE STUDY IN NURSES OF TWO DIFFERENT TYPE OF PRE-HOSPITAL EMERGENCY SYSTEM.
BURNOUT SYNDROME IN EMERGENCY. COGNITIVE STUDY IN NURSES OF TWO DIFFERENT TYPE OF PRE-HOSPITAL EMERGENCY SYSTEM.

Study objective: Burnout syndrome (BOS) associated with stress has been documented in health care professionals in many specialties. The pre-hospital healthcare services are highly stressful environments. Little is known about the BOS in critical care nursing staff. The objective of the study is to compare the incidence of BOS and its three domains, namely, emotional exhaustion, depersonalization and reduced professional accomplishment, in two cohorts of critical care nurses: a pre-hospital emergency service with an internal psychological support service and a pool of “classic” pre-hospital emergency services (without this additional service).

Methods: A survey using a questionnaire (the Maslach Burnout Inventory-General Survey, MBI-GS), among nurses of four Italian emergency services has been performed. One of these is in a Regional Hospital with a mean of 75770 interventions/year and has a dedicated psychologist who supports the nurses (PHES-Psy). The other 3 pre-hospital emergency services make a mean of 44562 interventions/year and don’t have a psycologic support service (PHES).

Results: All 68 nurses surveyed (51% female) filled the questionnaires. BOS-related symptoms have been identified in at least 85% of the nurses in the entire study  population. In the PHES group (n=52) BOS-related symptoms have been identified in 88% of the respondents. Among the PEHS-Psy nurses (n=16), BOS-related symptoms have been identified in 75% of the respondents. A medium-high emotional exhaustion was found in the 46% of the respondents in the PHES group and 62% in the PEHS-Psy (p=0.2). 60% among the PEHS nurses and 75% among PHE-Psy nurses soffered a medium-high depersonalization (p=0.8). 63% and 58% respondents had a medium-high reduced professional accomplishment respectively in the PEHS and the PEHS-Psy populations. Moreover, the likelihood that a nurse had a severe BOS, that is at least one degree of high burnout or ≥2 degrees of medium burnout, is 75% and 63% respectively in the PHES-Psy and the PHES group (p=0.4). However the frequency of severe BOS in the group of the PHES-Psy is lower than the same rate found in a previous (2014) survey (75% vs 90%, p=0.2). Taken into account that two important determinants of BOS are the amount of interventions and the years of work, we can speculate that the incidence of BOS in PHES-Psy is well controlled during the last two years.

Conclusion: More than two-thirds of critical care nursing staff had a severe BOS. The use of a psychological support service seems to limit the incidence and the grade of BOS among PHES-nurses. Further interventional studies are needed to better investigate this potentially preventive strategy.


Vincenzo G MENDITTO, Ilenia CARLETTA (Ancona, Italy), Giorgia CANNIZZARO, Chiara CICCHITTI, Roberto MACCARONI
08:30 - 17:40 #11245 - Can Anisocoria be a Predictive Factor for Cerebral Herniation in Trauma?
Can Anisocoria be a Predictive Factor for Cerebral Herniation in Trauma?

BACKGROUND

   Pupillary laterality does not always indicate cerebral herniation (CH) in traumatic brain injury (TBI), because its cause ranges from CH to cranial neuropathy or pupillary sphincter muscle injury. The aim of this study was to clarify whether anisocoria could be a predictive factor of CH in trauma.

 

METHODS

   Clinical records of all trauma patients with anisocoria,  admitted to the Hyogo Emergency Medical Center between January 2011 and December 2016, were retrospectively reviewed. Anisocoria was defined as difference in pupillary size of 0.5mm or above. Those patients were divided into the cerebral herniation (CH) group or the control (C) group, according to their initial head computed tomography images evaluated by board certified neurosurgeons. Systolic blood pressure, pulse rate, Glasgow coma scale (GCS), and presence of hemiplegia on admission were obtained. Patients were classified by GCS score into a low GCS (8 or lower), a moderate GCS (9 to 12) or a high GCS (13 or higher). The Abbreviated Injury Scale of head, face and surface, and the Injury Severity Score were graded. Single variable  (Chi-square test) and  multivariate logistic regression  were used for statistic analyses.

 

RESULTS

   During the study period, 123 trauma patients had anisocoria, and 39 of 123 had CH. In the H group, there were 33 cases in a low GCS, 5 in moderate GCS, and 1 in high GCS. In the C group, there were 21 in a low GCS, 21 in a moderate GCS, and 42 in a high GCS. The single variable analysis revealed there was a significant difference between the C and the H group (P<0.05) in a GCS classification and hemiplegia(16 in H, 12 in C). A multivariate logistic regression analysis identified  GCS classification as an independent risk factor for CH (OR 2.06 [95%CI 1.21-3.53], P=0.008).

 

CONCLUSIONS

Only 30% of cases had CH among trauma patients with anisocoria. Although a GCS classification was an independent predictor, 21 of 54 (39%) cases did not have CH even in a low GCS. Anisocoria cannot be a reliable predictor for CH.


Keisuke MAEDA (Hyogo-ken, Japan), Shota KIKUTA, Satoshi ISHIHARA, Shinichi NAKAYAMA
08:30 - 17:40 #11429 - Can diastolic blood pressure decrease in emergency department setting be anticipated.
Can diastolic blood pressure decrease in emergency department setting be anticipated.

Introduction: There are no obvious guidelines for therapy of elevated blood pressure (BP) in the emergency department (ED). Diastolic BP is probably more difficult to control compared with systolic BP.

Aim: This study aim was to characterize patients who respond with a significant decrease in diastolic BP in the ED, whether treated or not.

Methods: In this retrospective cohort study, all patients attending a tertiary care ED with elevated BP were evaluated.  Clinical characteristics of patients in whom diastolic BP decreased ≥ 20% were compared with those in whom diastolic BP decreased < 20%.

Results: Overall, 391 patients were included in the final analysis (64% females), of which diastolic BP of 106 (27%) patients decreased ≥ 20%. Patients in whom diastolic BP decreased ≥ 20% were older [70.1±13 years vs. 65.9±16.7 years, P=0.011] and had a history of ischemic heart disease (IHD) and cerebrovascular disease (CVA) prior to the ED visit [30 patients (28.3%) vs. 45 patients (15.8%) for a history of IHD, P=0.005 and 16 patients (15.1%) vs. 21 patients (7.4%) for CVA respectively, P=0.02]. 

Conclusions: A history of cardiovascular disease  was associated with a higher decrease in diastolic BP irrespective of the use of medical treatment during the ED visit .


Irit AYALON-DANGUR, Alon GROSSMAN, Shachaf SHIBER (Tel aviv, Israel)
08:30 - 17:40 #11912 - Can infrared cameras be used in the emergency department as a prognostic tool: A prospective observational study?
Can infrared cameras be used in the emergency department as a prognostic tool: A prospective observational study?

Background

A major commitment in an ED is to identify the most sick. Several systems exist, most rely on vital sings, and thus require these to become abnormal to reliably identify patients at risk. But when vitals sings deteriorate, it becomes difficult to treat. What if we could find the patients who are not only sick right now but also the patients with an increased mortality risk within the next 30 days.

A recent observational study from our group, using infrared thermography, investigated if the temperature difference between the inner canthus of the eye (representing core temperature) and either the tip of the third finger, the tip of the nose or ear lope could predict 30-day all-cause mortality. This study included 198 patients and found a significant association between the temperature gradient and mortality.

With this study, we aim to investigate if we, using the temperature gradient between central and peripheral temperature from infrared thermography, can identify patients at increased risk of short term mortality. We also wish to compare the predictive capability of infrared thermography with individual vital signs, an early warning score and clinical assessment by doctors.

Methods

In this prospective observational study, we included consecutive adult medical patients from the Emergency Department at the Odense University Hospital (October 2016 to May 2017). Using the unique Danish personal identification number, we had complete follow up at 30 days.  We excluded patients unwilling or unable to give informed consent as well as patients in the highest triage category.

Approximately 30 minutes after arrival (and no later than 3 hours), we took a standardized infrared thermographic image of the face and hand. We calculated the temperature gradient between the core temperature (inner canthus of the eye) and peripheral temperatures (tip of 3rd finger, ear lope and tip of nose). We also asked the treating physician of estimate short term mortality using clinical intuition on a scale of 0-100%.

The association between the measurements and the end point was assessed as the area under the receiver operating characteristics curve (AUROC). Our primary endpoint was 30 day all-cause mortality. The need for approval by the regional ethics committee was waivered by the committee.

Results

We screened a total of 936 patients and 678 (72%) were included. Some 306 have been analyzed thus far.

Median age was 63 (range 18-101) years and 49% were male. 60 (20%) were in the 2nd highest triage category, 161 (53%) in the 3rd highest and 75 (25%) in the 4th highest. One (0, 3%) patient died within 7 days, 2 (0,6%) within 14 days, 8 (3%) within 14 days and 11 (4%) within 30 days.

We still have not analyzed the association between the measurements and outcome.

Conclusion

With this study, we wish to show the association between infrared thermography and short term mortality as an alternative to vital signs, early warning scores and clinical assessment.

 


Nadia BENDIXEN (Odense, Denmark), Mikkel BRABRAND, Morten LORENTZEN
08:30 - 17:40 #11561 - Can simulated ABCDE scenarios for medical students improve their confidence in managing an acutely unwell patient in the Emergency Department?
Can simulated ABCDE scenarios for medical students improve their confidence in managing an acutely unwell patient in the Emergency Department?

Background: A number of global studies suggest that approximately 10% of patients admitted to hospital suffer some kind of harm. With these staggering statistics, there have been calls to develop techniques to combat medical error. One such method is simulation-based medical education (SBME) - an education tool which can mitigate errors and allows students to hone their skills in a safe learning environment, thus increasing their confidence to deal with patients in real life. Numerous studies have demonstrated that students who were taught in this manner reported higher levels of confidence in managing patients compared to their peers who did not receive simulation teaching. 

Aims: To ascertain whether carrying out simulated ABCDE scenarios for medical students can improve their confidence in managing an acutely unwell patient in the Emergency Deparment (ED). 

Methods: Data was collected from 29 3rd and 5th year students from Brighton and Sussex Medical School during their Emergency Medicine placement. They were asked to fill in a feedback form using a 10 point Likert scale (1=not confident at all, 10 = extremely confident) stating how confident they felt managing an acutely uwell patient PRIOR to the simulation session and AFTER the simulation session. They were also asked to record how useful they found the teaching and feedback elements of the simulation (1=not useful at all, 10 = extremely useful). 

Results: The mean score for students' confidence levels prior to the simulated scenarious was 5.86. This increased to a mean of 8.67 after the simulated scenarios. For all the students there was an increase of at least 1 point following the sessions with some increasing their confidence by 5 points in the Likert scale. The mean score for the usefulness of the teaching was 9.21 and the feedback was 8.93. 

Conclusions: SBME plays an increasingly important role in the education of medical staff, particularly students. Carrying out simulated ABCDE scenarios appears to subjectively improve the confidence of medical students to manage an acutely unwell patient in the ED by an average of 3 points on the Likert scale. The teaching element of the simulation was deemed the most useful aspect of the exercise by all students. 


Leah SUGARMAN (London, United Kingdom), Rosanna GRIMES
08:30 - 17:40 #11718 - Can you decide whether the patients with cervical spinal cord injury of ASIA B or C are required tracheotomy at the admission?
Can you decide whether the patients with cervical spinal cord injury of ASIA B or C are required tracheotomy at the admission?

Patients with cervical spine injury sometimes need ventilation and tracheotomy because their respiratory muscle are palalysis and it is difficult to take out sputum. So we investigate to find common thing in the patients who was done tracheostomy. A retrospective review of patients with acute cervical spinal injury admitted to Tottori University Hospital from 2010 to 2016 was performed.

There were 30 patients (26 male and 4 female) who had cervical injury by trauma and whose ASIA score were below C. The age was from 33 to 94 (average 69). 9 patients had a tracheostomy. Patients remained ventilator 1patients were died after injury.

The result is that the stay of the patients who had tracheostomy is longer and older and  patients weren’t removed intubation more than 1 week after admission.

And all the patients of ASIA A were done tracheotomy and we investigate the reason whether the patients of ASIA B or C were done tracheotomy or not.


Tomofumi OGOSHI (tottori, Japan), Masato HOMMA
08:30 - 17:40 #11421 - Capitulum Fracture after Fall on Right Elbow.
Capitulum Fracture after Fall on Right Elbow.

A case of a 27 years old female with right elbow fracture is presented here. She came to the Emergency department with history of fall on right flexed elbow one day earlier. On examination there was mild right elbow edema with no obvious injury. Tenderness present mainly on the lateral aspect of elbow. Movements were severely restricted in extension, she could not extend beyond 30 degrees, pronation and supination is almost not possible and forearm is in mid prone position. Sensations were intact in right forearm with radial and ulnar pulses palpable. X-ray right elbow was done which showed displaced Bryan and Morrey type I fracture of capitulum with mild joint effusion. Open reduction and internal fixation of capitulum was done with headless screws. Patient recovered uneventfully and discharged after three days with physiotherapy follow up.


Muhammad Faisal KHILJI, Muhammad Awais NAWAZ (, )
08:30 - 17:40 #10166 - Capnography and clinical decision making in the spontaneously breathing, non-intubated emergency patient - a systematic review.
Capnography and clinical decision making in the spontaneously breathing, non-intubated emergency patient - a systematic review.

Background
The critical relationship of EtCO2 monitoring and clinical decision making in the tracheally intubated patient is well-documented. The rationale and benefits from applying EtCO2 monitoring in the non-intubated cohort is, however, not well documented and guidelines and recommendations for its application are sparse. The aim of this systematic review was to investigate the possible benefits of capnography to clinical decision making in the spontaneously breathing, non-intubated emergency patient and thereby provide recommendations for its use.

Methods
A systematic search of studies comparing capnography monitoring and non-capnography monitoring in the spontaneously breathing, non-intubated emergency patient, published in the MEDLINE, SCOPUS, Cochrane, Academic Search Complete, and CINAHL databases from 1st of January, 1990 up to 24th of February, 2016 were performed. In total 409 studies were identified of which 11 (1 meta-analysis, 2 randomised controlled trials, 8 cohort studies) met pre-specified inclusion criteria, involving 1450 study subjects.

Results
The retrieved literature suggests capnography beneficial to clinical decision making in the investigated population. The included studies were, however, found to be of variable quality and strength with several risk of bias, methodological and technical limitations which led to questionable and inadequate conclusions.

Conclusions
This review found some sporadic benefits to clinical decision making when applying capnography to the spontaneously breathing, non-intubated emergency patient.
Until more evidence from high-quality studies are available, capnography in the investigated cohort should be utilised with a critical approach as it is not possible to adequately scientifically support recommendations and guidelines for its use.


Martin BETZER (Greve, Denmark), Rasmus LYNGBY
08:30 - 17:40 #11921 - Capnography during cardiopulmonary resuscitation. Is it only intubation friendly?
Capnography during cardiopulmonary resuscitation. Is it only intubation friendly?

Background: cellular metabolism produces carbondioxide while the lungs eliminate it. End tidal carbon dioxide (EtCO2) refers to the graphical presentation of carbon dioxide partial pressure in mmHg at the end of expiration. EtCO gives a clinical clue aboutr pulmonary pathophysiology.

Methods: 23 cardiac arrest patients admitted to Alexandria Main University Hospital were enrolled in the present study. All patients were resuscitated according to the Advanced Life Support (ALS) guidelines 2015. Chest compressions were started once cardiac arrest was confirmed. Endotracheal intubation was done by emergency resident with at least 2 years experience in emergency medicine. All patients were monitored using mainstream waveform capnography. The number of CPR cycles done and the average time consumed to obtain the first reading of EtCO2 were recorded. the duration of a single CPR cycle is 2 minutes according to the ALS guidelines. The first reading of EtCOwas taken as a method to confirm correct endotracheal intubation. Further EtCO2 values were r3ecorded during CPR and the average of these values during CPR was recorded for each case. The relation between the mean value of EtCOduring CPR and the patient outcome was studied.

Results: All patients enrolled in the study suffered Out of Hospital Cardiac Arrest (OHCA). The first reading of EtCOwas obtained after 3 CPR cycles in 13 patients (56.5%), after 2 CPR cycles in 9 cases (39.1%) and  after 4 cycles in only 1 case (4.3%). The mean time to obtain the first EtCO2  was 353.9 ± 69.3 seconds, and this was also the time consumed to confirm correct endotracheal tube placement. The value of the first reading of EtCO2 ranged between 8 -15 mm Hg with a mean value of 12.43 ± 2.79 mmHg. while during CPR the value of EtCOranged between 8 -25 mmHg with a mean value of 17.96 ± 7.61 mmHg, at the end of resuscitation, the value of EtCOranged between 0-45mmHg with a mean value of 21.3± 21.01 mmHg. 12 cases of the studied population had successful resuscitation efforts and return of spontaneous circulation, where11 patients (47.8%) were admitted to the ICU and 1 patient (4.3%) was transferred to the operating theatre. 11 patients (47.8%) had unsuccessful resuscitation efforts and died. There was a significant relation with significant p value <0.001 between the patient outcome and the value of EtCOobtained during CPR, where the value of EtCOin patients who had return of spontaneous circulation ranged between 20-25 mmHg with a mean value of 24.09 ± 2.02 mmHg, while the value of EtCO2 in the cases who died ranged between 8-15 mmHg with a mean value of 10.27± 1.68 mmHg. 

Discussion: The benefits of continuous EtCOmonitoring during cardiopulmonary resuscitation outweigh correct endotracheal tube placement. Continuous waveform capnography monitoring during CPR can give a clue regarding efficiency of chest compressions in addition to its prognostic value regarding successful reuscitation efforts. 


Asmaa ALKAFAFY (Alexandria, Egypt), Nagwa ELKOBBIA, Salah ELTAHAN, Moustafa ABDEL-AZIZ, Alaa-Eldin ABDALLAH
08:30 - 17:40 #11764 - Carbamazepine serum measure in acute carbamazepine poisoning : Is there any interest ?
Carbamazepine serum measure in acute carbamazepine poisoning : Is there any interest ?

Background : 

Carbamazepine (CBZ) poisoning is clearly increased because of the wide use of CBZ for treatment of simple or complex partial or seizures, trigeminal neuralgia, and bipolar affective disorder. It is also increased during the last 10 years, particularly as addicted drug in our country. We aimed to study is there any correlation between neurological signs and carbamazepine serum level.

Methods :

This was a retrospective observational study spread over 88 months from January 2010 to April 2017 including all patients admitted to our ICU for carbamazepine poisoning. 

Results :

201 patients aged of 29.5 years (12 ; 67) were eligible. They were 82 male and 119 female with a sex ratio was 0.7. A history of psychiatric disease was noted in 56% of cases, epilepsy in 15% and long term treatment with carbamazepine in 57% with a median duration of carbamazepine treatment of seven years.

The supposed ingested dose was 4.3 g (0.4 ; 20) and the delay between ingestion and hospital arrival was 5.7 hours (1 ; 26). 

Thirty three per cent of CBZ poisoning was associated to another drug coingestion. Physical exam showed coma 36% of cases (n=73), agitation in 26% (n=52) and seizures in five patients (2.5%).

The analysis of correlation between neurological signs and serum level CBZ on admission showed a low correlation between carbamazepine serum level and coma both for patients who ingested carbamazepine alone (r2 :0.016) and also for patients with multidrug poisoning (r2 :0.14)

Discussion:

Carbamazepine serum measure on admission doesen’nt appear to predict the severity of CBZ poisoning. It is better thow to study the serum CBZ kinetics then to emphasize on the CBZ serum level on admission.


Eya AYARI (tunis, Tunisia), Asma ALOUI, Malek HSOUNA, Mohamed MEZGHANNI, Othmen KEHILA, Nozha BRAHMI
08:30 - 17:40 #11767 - Carbon monoxide moderate and severe intoxications related to waterpipe use.
Carbon monoxide moderate and severe intoxications related to waterpipe use.

Background: Narghile (waterpipe, hookah) is a traditional method of tobacco use. In recent years, its use has increased worldwide, especially among young people. Compared to cigarettes, narghile smoking can result in a greater exposure to several volatile compounds, including carbon monoxide (CO). We evaluate the waterpipe-related CO-poisoning to assess the severity of the intoxication. Methods: All cases referred to our Poison Control Centre in a height-year-period (April 2008-April 2016) for CO intoxication were retrospectively reviewed, and narghile-related cases were selected and evaluated for (i) patient data, (ii) clinical manifestations, (iii) carboxyhemoglobin (HbCO) level at admission, (iv) treatment and (v) outcome. Results: Sixteen patients (M/F 13/3), aged from 17 to 47, were identified as waterpipe-related CO poisoning. Height patients had smoked alone, while in the other eight cases the patients smoked with other people. 15/16 patients had smoked tobacco, while only one had smoked hashish. Ten patients referred to an emergency department because symptomatic: syncope (5/10), headache (7/10), dizziness (2/10), vomit (3/10), diarrhea (1/10), dyspnea (3/10). HbCO level of symptomatic patients at admission ranged from 5,3 to 23,2% (average 14,2+/-7). Six patients were asymptomatic and undergo medical evaluation just because they smoked together with symptomatic patients: nevertheless, their HbCO levels at admission were positive ranging from 5,6 to 18,3% (average 8,4+/-5). Five of six asymptomatic patients were discharged in twelve hours after cardiac evaluation and normobaric oxygen treatment. Eleven patients were hospitalized for further clinical evaluations and for normobaric (7/11) or hyperbaric oxygen treatment (4/11). All patients were discharged without sequelae. A forty-day clinical follow-up was performed. The symptomatic patient who smoked hashish manifested syncope with short pseudo paresis of limbs; his HbCO level was 11,5% three hours after smoking. Conclusion: Narghile smoking exposes to the same harmful substances of cigarette smoking (CO included), although in greater quantity due to the duration of smoking/inhalation (approximately 5 minutes for cigarettes, 50 for narghile) and to the combustion temperature. The amount of CO in smoke is mostly related to waterpipe size and tobacco type. Moreover, waterpipe smoker inhales CO as a result of the charcoal combustion. CO intoxication, even severe, may occur, and it’s reasonable to believe that this cases are underestimated. This diagnosis should be considered in case of non-specific neurological symptoms.


Carlo Alessandro LOCATELLI, Federico VIGORITA, Sara DI GIULIO, Marta CREVANI, Francesca CHIARA, Valeria Margherita PETROLINI, Davide LONATI (PAVIA, Italy)
08:30 - 17:40 #11828 - Cardiovascular Impact of Brain Injuries.
Cardiovascular Impact of Brain Injuries.

INTRODUCTION :

The clinical importance of cardiovascular consequences resulting from cerebral injury has been well studied. However, interactions between the brain and the cardiovascular system are not well understood and their importance for the management of patients suffering from acute brain injury is underestimated. This study was conducted to evaluate cardiovascular consequences of cerebral injury relying on serum levels of the High-sensitive troponin (hsTnT).

METHODS :

We conducted a prospective study in the emergency departement (ED) in which we included all the patients presentend to the ED with cerebral agression ( cranial trauma, stroke, subarachnoid hemorrhage, seizures). All patients had troponin (hsTnT) test and electrocardiogram. We excluded patients with chest pain or coronary history.

RESULTS :

We enrolled 170 patients. The mean age was 56 ± 15. The sex ratio was 1.39. 55 patients (32%) had cranial trauma, 66 patients (38%) had a stroke, 33 patients (19%) had a seizure and 16(9%) patients had subarachnoid hemorrhage.

Troponin elevation was noted in 97% of  patients with subarachnoid hemorrhage , chez 20% of patients with seizure 8%  of patients with stroke. ECG abnormalities like ST/T changes were noted in 33% of patients with subarachnoid hemorrhage and in 3% of patients with stroke.

Conclusion :

Cardiac troponin release occurs frequently after brain injury and specifically after subarachnoid hemorrhage and has been associated with a neurogenic form of myocardial injury.


Yousra GUETARI (Tunis, Tunisia), Dhekra HAMDI, Mounir HAGUI, Rim HAMMAMI, Bassem CHATRBI, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11166 - Carpopedal spasms as the first symptom of Lung Cancer.
Carpopedal spasms as the first symptom of Lung Cancer.

Objetive: Give importance to the correct exploration and study of patients with nonspecific symptoms

Method: A 51-year-old female patient who came to the emergency room for perioral paresthesias and carpopedal spasms during two hours. She is accompanied by her family who relates symptoms to low mood due to personal problems and reports that they have already consulted their doctor for the same reason and started treatment with antidepressants because of anxiety. In addition it refers catarrhal disease in previous days as well as weight loss due to anorexia related to depressive syndrome. Diazepam 5 mg is administered sublingually by the profuse symptomatology on arrival. Clinical examination: Tubal murmur in right base pulmonary auscultation. Hemogram was performed, with anemia (Hb: 9 mg / dl), hypokalemia (K. 2.8 mEq / L), hypocalcemia (6.8 mg / dl) and hypomagnasemia (0.8 mg / dl). In gasometry Respiratory alkalosis. Torax X-ray:condensation in the upper right lobe of the right atelectasia. Entered by Internal Medicine for Hypocalcemia and Pulmonary Mass to study.

Results: CT scan of thorax, PET evidencing Pulmonary mass of Hipermetabolic compatible with neoplastic lesion confirmed with Biopsy and Hypocalcemia by Hypovitaminosis D from carencial origin. After intravenous treatment, normalization of analytical data and improvement of the clinic was achieved.

Discussion: The reasons for consulting the ER are, in many cases, nonspecific and suggestive of banal pathologies but a correct clinical examination and systematic study can perform diagnoses of important clinical entity.


Rocio RODRIGUEZ BARRIOS (MALAGA, Spain), Ana PEREZ TORNERO, Pino SALINAS
08:30 - 17:40 #10973 - Case Report : Open Total Talus Dislocation, a rare but severe injury of the ankle.
Case Report : Open Total Talus Dislocation, a rare but severe injury of the ankle.

Introduction

Total talus dislocation is a rare injury due to excessive supination or pronation of the ankle joint. Only a few case reports have been published and no concrete data regarding incidence rates for this injury.This case report describes a patient with an open talus dislocation associated with medial malleolus fracture that was treated with early surgical intervention and stable fixation.

 Case Report

A 30 yo man was transported by the prehospital EMS for multiple trauma after being involved in a motor vehicle accident with an oncoming car..He was conscious CGS 15 complained of severe pain in the right ankle. Examination revealed a severe head trauma, multiple wounds on a right leg, left hand and total talus dislocation with the talus being exposed with a contaminated wound at the anterolateral side of the ankle. Neurovascular integrity was not compromised. ISS Score 48. The total-body computed tomography scanning (TBCT) confirmed a total talus dislocation with an associated displaced medial malleolus fracture.

The patient was admitted for immediate intravenous antibiotic therapy and surgery .

The talus was reduced and screw fixation of the medial malleolus was realized, an external fixator was applied to maintain stability of the ankle.  

After 3 months of follow-up the patient had a osteochondritis and an evolutive algodystrophy on his right leg, knee and ankle. 2 years after the accident the patient had a relative excellent recovered evolution with a limitation of 50 % lateral movements of his ankle.

 

Discussion: Total talus dislocation occurs when the talus is entired detached and dissociated from the tibiotalar, talonavicular and subtalar joints. It results from a high energy motor vehicle accident or fall from height. Total dislocation of the talus is usually associated with fractures of the malleoli or the talus itself.. Total extrusion involves disruption of vascular supply to the talus, predisposing to osteonecrosis. Infection, avascular necrosis and post-traumatic arthritis are the most major complications.

Orthopedics surgical recommendations suggest wound debridement, early reduction and fixation to avoid infection, provide early revascularisation, and to preserve the normal ankle anatomy. Based on previous reports, the role of the Emergency Physician is relatively complex : clean and the talus still attached, keep the environment close to the original biological state encouraging early revascularisation. However, development of post-traumatic osteoarthritis is still possible and may present years after initial injury.


Eric REVUE (Paris), Sophie RACINE, Alexandre HENNIART, Stephanie LEGROS, Jehad KASSAB
08:30 - 17:40 #10941 - Case report of a rare punching injury - luxation of the carpometacapal joint.
Case report of a rare punching injury - luxation of the carpometacapal joint.

Background:

Because CMC joints are very stable related to strong transverse dorsal ligaments and longitudinal volar ligaments, dislocations of these joints are rare. These injuries present in less than 1% of hand injuries and are associated with high energy trauma, mainly related to motor bicycle accidents. Dorsal CMC joint dislocations are more common than ventral CMC joint dislocations.

Because patients with high energy trauma often present to the emergency department with other more obvious traumatic injuries, CMC joint dislocations can be missed in up to 30-50%.

In addition, dislocations of the CMC joint can be missed in patients who present with subtle findings on physical and radiographic examination at initial presentation on the emergency department.

With this report of an untypical presentation of a punching injury we will increase the awareness that CMC joint dislocations can also be related to a low energy trauma.

Case summary:

A 30 year old man without any significant medical history presented to our emergency department several hours after beating a brick wall in a state of emotional stress. He complained of pain in his dominant right hand.

On examination the right hand was deformed with a soft tissue swelling on the dorsal and ulnar side of the hand. The patient was unable to move his wrist related to pain and kept the hand in a neutral position. There was no neurological or vascular impairment and no additional injury. There was no obvious rotational deformity of the fingers.

To exclude a fracture or luxation an x-ray of the right hand was performed. The x-ray study showed a fracture of the proximal fourth metacarpal bone with fragments between the base of the third and fourth metacarpals. Furthermore, there was a dorsal dislocation of the third and fourth metacarpals.

For preoperative planning  a CT scan of the right hand was performed which showed a luxation of the fourth and fifth carpometacarpal (CMC) joints with a dorsal and proximal dislocation of approximately 1 cm and a fracture of the base of the fourth metacarpal with multiple bone fragments.

The consulted trauma surgeon performed a closed reduction of the CMC joint dislocation and internal fixation with Kirschner wire and an additional short arm cast.

Conclusion:

CMC dislocations are rare hand injuries and normally related to a high energy trauma. In this case the CMC dislocation was related to a low energy trauma. Careful hand examination and radiographic assessment including anterior-posterior, lateral and posterior-anterior oblique views with a systematic approach of both intercarpal and CMC joints are necessary to avoid missed diagnosis of CMC joint fracture dislocation. A CT should be performed for preoperative planning but even if in doubt about a possible dislocation. When left untreated or treatment is delayed, these injuries can lead to chronic pain, stiffness and posttraumatic arthritis. Delayed treatment will also increase need for open reduction.


Christian HERINGHAUS, Egbert KRUG, Michel Johannes VAN DER GEEST (Leiden, The Netherlands), Ralph Lennart WIDYA
08:30 - 17:40 #11223 - Case report of traumatic cardiac arrest recovered after pericardiocentesis of hemopericardium.
Case report of traumatic cardiac arrest recovered after pericardiocentesis of hemopericardium.

Introduction:

Weapon wounds represent 1% of victims in prehospital care. Located in abdomen or thorax area, these penetrating injuries are serious life-threatening conditions. In particular, heart wounds represent a lethal condition with high mortality rates (60-90% of patients die on the scene or during transport). This situation requires an urgent, rational and adequate treatment to improve patients' prognosis.

Case report:

We report the case of a 24-year-old man, victim of thoracic stab wound. The EMS team arrived 5 minutes later in the scene. The patient was in a cardiac arrest with a wound at the 5th left intercostal space. Chest compressions have been started by a witness.  Monitoring showed asystole. Advanced cardiopulmonary resuscitation was initiated. The patient was intubated and adrenaline injection given every 4 minutes. The possible causes of cardiac arrest were checked: hypoxia was treated by oxygen,  no massive pneumo or hemothorax were excluded, hypovolemia by haemorrhage was evoked and controlled by fluids.  Cardiac tamponade was strongly suspected because of jugular vein distension. Percutaneous pericardiocentesis was  practiced  by subxiphoid approach after 20 minutes of CPR which allowed the aspiration of  60 ml of blood. Twenty minutes later, the patient return to sinusal rhythm and recovered spontaneous circulation. He was transferred to operating theatre. Two wounds were repaired in the right ventricular with a good circulatory and neurological evolution in intensive care unit  allowing  withdrawal of ventilatory support and patient's discharge from hospital 3 days later alive and in good health.

Discussion:

Cardiac wounds are dominated by right ventricular wounds (45% of lesions), then the left ventricle (32%), the atria (15%) and finally the pericardium (9%). There is no unique symptoms for these heart stab wounds but they frequently induce tamponade in 80% to 90% of cases.  Location of the wound at the 5th left intercostal space at the sternal border was very suggestive of a direct cardiac injury with pericardial effusion.  Presence of a witness who started CPR and optimized resuscitation with optimal control of reversible causes in prehospital care (tamponade, hypovolemia...) were determining for recovery of spontaneous circulation and good outcome. Fast et concise alert of anaesthesiologists and cardio surgeon team, by the medical regulation, allowed optimization of adequate management of this cardiac wound and the haemorrhage's control.

Conclusion:

The improvement of recovery rates and outcome of traumatic cardiac arrest involve  optimization of every link of the survival chain: from the first witness to  post-resuscitation care. Optimal management in prehospital care is primordial. Every reversible cause might be evoked and eventually treated to allow recuperation


Hajer KRAIEM (Sousse, Tunisia), Majdi OMRI, Amal BACCARI, Fatma BOUKADIDA, Mohamed Aymen JAOUADI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11743 - Case report: a rare complication following colonoscopy: subcutaneous emphysema.
Case report: a rare complication following colonoscopy: subcutaneous emphysema.

Introduction: Colonoscopy is a widely-used procedure evaluating, diagnosis and treatment of gastrointestinal diseases. That’s why its complications are well diagnosed. We present a rare and interesting complication following diagnostic colonoscopy.

Case: A 41 years old female admitted to our Emergency Department with pain in the neck. At the physical examination, there was crepitation and swelling on the right side of the neck that extends along 2nd rib. In her history, it was learned that nearly before 3-4 hours she had have diagnostic colonoscopy for etiologic research of constipation and diagnostic polypectomy was performed from rectosigmoid junction. Although the abdominal examination and X-rays were normal, considering perforation, computerized tomography was taken and retroperitoneal air images, subcutaneous emphysema from right cervical area to chest and pneumomediastinum were seen. The patient given to the surgery due to the diagnosis of perforation. After the primary repair the patient was hospitalized for 8 days and discharged.

Discussion: In America 14,2 million colonoscopies were performed in 20021. Perforation is a rare but threatening complication of this procedure. Its rates range from 0,003-0,12%2,3. There are some risk factors of perforation following colonoscopy like advanced age, male sex, low volume endoscopic service, significant comorbidity, obstruction as an indication for colonoscopy and performance of invasive interventions4. Three mechanisms are responsible from perforation; mechanical perforation, overzealous air insufflation or barotrauma and after therapeutic procedures such as polypectomies and biopsies5. Patients with intraperitoneal perforation usually may present with abdominal pain, peritoneal irritation signs and rarely respiratory symptoms. Retroperitonal air can move upwards to the mediastinum from the hiatus aorticus and IVC, continue along facial planes into the neck resulting in cervical subcutaneous emphysema6. Treatment of perforation following colonoscopy is simple and safe for patients without peritonitis. Alternatives of the modalities are conservative treatment with nasogastric catheter and antibiotics and surgical treatment like primary repair or resection7.

Conclusion:  By the increase of colonoscopy rates for colorectal cancer screening, the incidence of colonic perforation rates is expected to rise. For the patients care physicians should be aware of the rare signs of perforation beside common ones. 


Semanur KARADADAS, Tuba SAFAK, Emine EMEKTAR (Ankara, Turkey), Handan Ozen OLCAY, Yunsur CEVIK
08:30 - 17:40 #11852 - Case Report: Extensive Anterior Abdominal wall muscles Hematoma,A life-Threatening, Unfortunate Consequence of Novel Antiplatelet Therapy.
Case Report: Extensive Anterior Abdominal wall muscles Hematoma,A life-Threatening, Unfortunate Consequence of Novel Antiplatelet Therapy.

Background:

Abdominal wall Hematoma including Rectus sheath(RSH) is uncommon cause of acute abdomen that is often clinically misdiagnosed.It should be included in the differential diagnosis of every patient who presents with abdominal pain

Case:

66-year-old male patient,known case of Hypertension,CAD post CABG(Aspirin & Clopidogrel) presented to Emergency Department-Hamad Hospital with acute severe left sided abdominal pain after a cough attack that lasted for 15 minutes.He had URTI for 3 days,no fever,vomited once.Normal bowel habits.On examination,HR100min,BP:110/70,SPO2:97%,Lungs clear,Normal heart sounds.Guarding & tenderness on the left abdomen from the middle-suprapubic with palpable,non-reducible mass.Bowel sounds positive.Diffrential Diagnoses was Incarcerated hernia,Ruptured AAA, Diverticulitis.Chest & abdominal Xrays insignificant.General surgeon consulted,CT abdomen requested.Received 1liter Normal Saline,Morphine 10 mg IV.WBC 6.4,HB 10.9(was 13 gm 1 week ago),Platelets102,INR1.1

After 2 hours,patient became dizzy,sweaty,with increasing abdominal pain.BP:100/60,HR:168/min,SPO2:97,ECG SVT.He received 3doses of Adenosine,reverted to sinus rhythm.

Bedside US:No free fluid in abdomen,Aorta 2 cm,a heteroechoic,well-defined mass in anteriorolateral abdominal wall suggestive of wall hematoma

Received 2 units PRBC,2 FFP,both Aspirin & Clopidogrel were held.

CT abdomen showed large left Rectus Sheath Hematoma extending to anterior abdominal muscles(External,Internal Obligues & Transverse abdominal)with active contrast extravasation.

Angiography showed active Left Inferior Epigastric Artery extravasation & hence Embolization embolization was done

Patient had stable course, was discharged home after 5 days.

Discussion:

Bleeding occurs from rupture of the Inferior or Superior Epigastric arteries or a muscle tear.Initially it's confined to the Rectus Sheath but when continued,can dissect into preperitoneam(pelvic hematoma),retroperitoneam or intraperitoneam.

Careful history should include directed questions regarding surgical procedures,blunt trauma,coughing,sneezing,constipation or exercise.Coughing causes intense contraction of the rectus muscle with tearing the perforating branches of Inferior Epigastric vessels within the muscle especially patients on anticoagulants.

Large hematomas resulting in hypovolemia require emergent management,prompt and accurate diagnosis,anticoagulation reversal,fluid resuscitation or transfusion,and hemodynamic stabilization.If bleeding continues angio-embolization or surgical ligation of bleeding vessels is required

Conclusion:

Emergency Physicians should always consider anterior abdominal wall muscle hematoma in differential diagnosis of abdominal pain even in absence of anticoagulantion or trauma or the diagnosis will be easily overlooked. Bedside abdominal ultrasound by trained emergency physicians,can diagnose,in a timely manner Life-threatening conditions and expedite proper consultations,definitive care and better outcome.


Lubna Ghali Amin ANDRAOUS (Doha, Qatar), Ashad HANNAN
08:30 - 17:40 #11900 - Case Report: Use of POCUS to Diagnose Massive Hemoperitoneum from a Corpus Luteum Cyst Rupture.
Case Report: Use of POCUS to Diagnose Massive Hemoperitoneum from a Corpus Luteum Cyst Rupture.

Background:

Acute pelvic pain in women is a common cause emergency room visits.Sometimes,it can be difficult to distinguish gynecological from gastrointestinal and urinary tract emergencies because of overlapping symptoms and signs

Methods:

We report a case of a young patient,where an emergency physician,utilized bedside ultrasound not only to identify massive hemoperitoneum but also to relate the source of bleeding to a hemorrhagic Corpus Luteum cyst.Findings confirmed intra-operatively 

Case:

29-year-old female patient,presented to Emergency Department-Hamad Hospital,with lower abdominal pain,vomiting & dysuria.Her last menstrual period was 20 days before & regular.No history of vaginal bleeding.(BP110/60),(HR88bpm),(Temp36.5C). Abdomen was not distended,soft & with lower abdominal tenderness,bowel sounds were positive.working diagnosis was Urinary Tract Infection.She received 2 Liters IV normal saline,2 grams IV Ceftriaxone,anti-emetics & analgesia.Investigations(WBC23,000),(Hb7.9 g/dL),urine 2+WBC,nitrite negative & serum BhCG was negative.Departmental ultrasound abdomen was requested.

After 6 hours,patient had dizziness,increasing abdominal pain,(BP90/50),(HR136bpm).Bedside ultrasound was done,showed large hemoperitoneum,with organized Cul-de-sac hematoma measuring(12.5 X 8.5cm) more around the Left ovary & a left ovarian cyst,suggestive of ruptured Corpus Luteum Cyst.Gynecologist was informed.Hb fell down to 6.1gm/dL.Patient was transferred to Operating room (OR). Laparoscopy showed a Left ovary ruptured Corpus Luteum,with estimated hemoperitoneum of 1500ml.Hemostasis was maintained and the ovary was secured.Patient received 6 units of PRBCs.

Discussion:

The most common gynecological causes of haemoperitoneum in reproductive aged women are Ectopic pregnancy and Ruptured Corpus Luteal cysts. Corpus Luteum is a remnant of the ruptured ovarian follicle after ovulation.It is a functional cyst developing in the luteal phase of the ovarian cycle which regresses spontaneously in corpus albicans when pregnancy does not occur.Being a thin-walled vascular structure,it is prone to hemorrhage even if bleeding is usually contained inside the cyst.It is usually asymptomatic, but rarely causes life-threatening hemoperitoneum requiring surgical intervention.It should be in the differential diagnosis for all females with abdominal pain,regardless of the location.This condition should be promptly recognized and treated because a delayed diagnosis may significantly reduce women’s fertility and intra-abdominal bleeding may be life-threatening.Negative pregnancy test is important to exclude ruptured Ectopic Pregnancy

Conclusion:

Early POCUS by a trained emergency physician is a helpful timely tool for assessing gynecologic structures, given its low cost, availability,and sensitivity in recognizing ectopic pregnancy,adnexal cysts and hemoperitoneum.Corpus luteum cyst rupture with consequent hemoperitoneum,is a common disorder considered in women in their reproductive age

 

 

 


Lubna Ghali Amin ANDRAOUS (Doha, Qatar)
08:30 - 17:40 #11192 - Case Report: Use of POCUS to Diagnose Type A Aortic Dissection in Emergency Department.
Case Report: Use of POCUS to Diagnose Type A Aortic Dissection in Emergency Department.

Back ground;

Aortic Dissection is a relatively uncommon yet life-threatening condition with a high morbidity and mortality rate.It remains a challenging diagnosis for emergency physicians,due to its wide range clinical manifestations and atypical presentations.Diagnosis is difficult,but essential,considering the time-sensitivity of initiating treatment with intravenous antihypertensive agents and operative intervention.Early recognition and treatment are crucial,especially when the proximal Aorta is involved.Dissections involving the Aortic Arch can lead to Myocardial Infarction,Pericardial Tamponade and Aortic valve failure resulting in death

Aim/Methods:

We report a case where an emergency physician utilized Bedside Transthoracic Echocardiogram & Abdominal Ultrasound to diagnose Type A Aortic Dissection in a timely manner (15 minutes from presentation) inspite of atypical presentation.We reflect that aortic dissection is diverse in its manifestations & not uncommon in young healthy patients

Case :

35 year old male, presented with acute onset of SOB, that started at rest for about 3 hours with productive cough. No chest pain/back pain/fever.Looked sick,HR110/min,BP(R)135/65,(L)127/60,RR36/min, SPO2 93%.Chest bilateral basal crepts,Normal S1S2 sounds with early diastolic murmur,raised JVP.All peripheral pulses were equal & symmetrical,with neither radiofemoral delay nor peripheral edema.There was no femoral bruit or focal neurological signs.EKG sinus Tachycardia

Bedside Echocardiogram was done & showed EF 35%,Moderate Aortic regurgitation,no pericardial effusion,a dilated Aortic root measuring 5.9 cm with a visualized intimal flap extending from the Aortic Arch to the Descending Thoracic and Abdominal Aorta.No free fluid in the abdomen was seen.Multiple Bilateral extensive B lines on lung US

Cardio Thoracic surgeon was immediately consulted.CT Angiogram confirmed the diagnosis of extensive Type A Aortic Dissection.Patient had emergent Aortic surgical repair,stable course of hospitalization & was discharged in good condition

Discussion:

Clinicians should have a high index of suspicion for the atypical presentation of Aortic Dissection.Aortic dissection is a catastrophic condition with significant mortality.It is fatal if not recognized early and treated with aggressive medical and/or surgical therapy.There are several benefits to use Bedside Ultrasound at the point of care to diagnose Aortic Dissection.It provides not only a rapid,noninvasive study, but also has a high specificity for detection of Aortic Dissection.It evaluates other potential life-threatening emergencies such as concomitant Abdominal Aortic Aneurysm,intraperitoneal hemorrhage, Pericardial Effusion/Tamponade and Aortic regurgitation

Conclusion:

This case highlights the fact that, Bedside Trans-Thoracic and abdominal ultrasound by trained emergency physicians,can diagnose,in a timely manner Life-threatening Aortic Dissection and expedite proper consultations,definitive care and better outcome

 


Lubna Ghali Amin ANDRAOUS (Doha, Qatar)
08:30 - 17:40 #10630 - CASTS, CLOTS & CLEXANE VENNOUS THROMBOEMBOLISM IN LOW RISK PLASTER IMMOBILISED PATIENTS.
CASTS, CLOTS & CLEXANE VENNOUS THROMBOEMBOLISM IN LOW RISK PLASTER IMMOBILISED PATIENTS.

Background :

Lower limb injuries requiring immobilisation are a common presentation to the ED. Most of these patients are managed by applying casts or splints. Incidence of VTE in patients with lower limb immobilisation is estimated between 5-39%. Thromboprophylaxis has been recognized to be highly effective in preventing VTE. A considerable amount of literature has focused on VTE prophylaxis in post-surgical and hospitalised patients. In contrast, little data is available for non-surgical ambulatory patients. A recent UK survey indicated that more than 60% of departments do not routinely use thromboprophylaxis. This lack of consensus seems to be due to the absence of clear guidelines.

Aim

1) Appraise the available evidence for low risk ambulatory patients having no risk factors for venous thromboembolism with isolated lower limb injury requiring temporary immobilisation with plaster cast.

2) Assess general awareness of VTE risk among emergency medicine doctors.

Methodology :

a) Literature review:

Inclusion Criteria; Aged 16years or over, isolated lower limb injuries, ambulatory non-hospitalised patients.

Exclusion Criteria; Paediatric patients < 15years old, post-operative patients, splint and walking boot immobilisation, conference reports, case studies, editorials and conference abstracts,The studies published in a language other than English.

b) Conducted departmental audit for VTE risk assessment in lower limb immobilisation by retrospective case note review of 100 patients at University Hospital .

c) Conduct a survey regarding awareness of VTE risk in patients with lower limb injuries requiring temporary immobilisation among Emergency Medicine doctors.

Most of the DVTs found are asymptomatic and there is  lack of general consensus whether or not to treat these distal DVTs. The clinical relevance of these distal DVTs cannot be ignored as 20-50% of theses may well cause damage to veins and consequently predispose patients to PTS. Craik et al demonstrated that blood flow in the calf significantly reduces when patients are immobilised in rigid casts and patients who are either partial or non-weight bearing.

Discussion :

Survey reveals lack of general awareness.

We recommend;

1) All patient with lower limb injuries requiring temporary immobilisation should be risk assessed.

2) All patients over 20years with plaster immobilisation who are partial or non-weight bearing are at higher risk of VTE irrespective of other risk factors.

3) All patient who are full weight bearing and have at least one risk factor should be considered for thromboprophylaxis.

4) All departments should have clear VTE guideline for lower limb immobilisation.

Recomendations :

We could not find a strong evidence proving VTE risk in low risk immobilised patients. We recommend further ED-based, prospective, multi-centred, blinded, randomised controlled, UK based studies with adequate sample size are recommended for risk analyses in this cohort of patients to further support out recommendations


Obaidullah ZAFAR, Mehtab KHAN, Hamid ILYAS, Abdul JALIL (Birmingham, United Kingdom)
08:30 - 17:40 #11879 - Ceftriaxone Usage in Academic Emergency Departments: Evidence Based Utilization or overuse.
Ceftriaxone Usage in Academic Emergency Departments: Evidence Based Utilization or overuse.

Abstract

Introduction: Ceftriaxone is being used, widely, these days, and it is less according to the current guidelines. The aim of this study was to determine the logical and non-logical uses of ceftriaxone. Considering the results may help looking for a way to prevent its inappropriate use in Emergency Department (ED).

Materials and methods: In an observational-analytical study, the patients referred to EDs of two teaching hospitals since September 23, 2015 to March 19, 2016 who have been treated with ceftriaxone, were analyzed. The rational usage of ceftriaxone was determined based on latest evidence based literatures.

Results: Ceftriaxone had been prescribed logically in 156 patients (38.4%; 95% CI, 33.5-42.9%) and its use did not meet logical criteria in the rest of cases consisting of 250 patients (69.6%; 95% CI, 57.1-66.5%). Logical use of ceftriaxone was independently related to treatment-goaled use, level I triage, urinalysis (U/A) compatible with urinary tract infection (UTI), and chest radiographic evidence of pneumonia.

Conclusion: Our study revealed a range of logical use of ceftriaxone not acceptable for a teaching medical center; more education seems to be necessary in this field


Dr Mahdi REZAI (Tehran, Islamic Republic of Iran), Hasan SAFEHIAN
08:30 - 17:40 #10897 - Central nervous sytem infections management in the ED: a race againt time.
Central nervous sytem infections management in the ED: a race againt time.

Introduction

When it comes to infections of the central nervous system (CNS), the greatest challenge in the Emergency Department (ED) is identifying patients that have a life-threatening diagnosis amid the patients presenting with nonspecific symptoms. Alone or in combination, fever, headache, altered mental status, and behavior changes encompass a broad differential diagnosis. Antibiotics or antiviral therapy should be given as soon as possible to patients with suspected CNS infection, ideally after both blood and cerebrospinal fluid (CSF) have been obtained for culture. Early treatment is associated with a lower mortality.

Methods

We present here, a four-year (2012-2015) retrospective and monocentric study conducted in a French teaching hospital. During the period of the study, we included all adult patients with the diagnosis of CNS infection (positive CSF culture). We collected and analyzed all clinical, biological, imaging, treatments and evolution datas during the stay. A total of 67 patients with CNS infection have been included for statistical analysis. We also analyzed a second group (n=25) with suspected CNS infection in the ED (negative CSF) as a control group.

Results

In the study population, mean age was 43±21.5 years old and the sex-ratio was 1.2. There were no difference between the two groups in terms of clinical signs except for more altered mental status in the control group (p=0.02). Admission parameters were also non different at the ED entrance. Biological results were non different except for thrombocytopenia more frequent in the postiv CSF group (p=0.0008). All patients of the study (n=92) benefited of lumbar puncture (LP) in the ED with an average time of 381±370 minutes after admission. This delay was the same betwwen the two groups (p=0,76) but was significantly higher in the encephalitis subgroup (n=13, p=0.03). Patients who had imaging (CT scan or MRI) during the ED stay had more likely a delay in LP realization (450 vs 193 minutes, p=0.0005). Patients where the CNS infection diagnosis was firstly evoke by the triage nurse had LP more quickly (p=0.03). The median door to-antibiotic-time was 339 minutes (IQR: 198-534) with no difference between the two groups of the study (p=0.70). A total of 86 patients (94%) were hospitalized for an average lengh of stay of 11.7±15.5 days and 10% of them were admitted in the ICU. The in-hospital mortality was 14% in the study population.

Conclusion

Our study highlights the poor adherence to guidelines. The management of CNS infections  remains slow and heterogeneous. Clinical features alone can not determine whether CNS infection is present and analysis of CSF is essential for diagnosis. Management practices, such as the timing of LP realization or antibiotics in relation to the return of CT scan or CSF results are the most important factors associated with antibiotic timeliness. In many cases, the avoidance of certain management practices represents an area of potentially avoidable delay.


Arnaud PERRIGUEY, Pierrick LE BORGNE, Elena Laura LEMAITRE (STRASBOURG), Florent BAICRY, Sarah UGÉ, Mihaela MIHALCEA-DANCIU, Etienne QUOIRIN, Pascal BILBAULT
08:30 - 17:40 #10861 - Challenges in the collaboration with other departments, weekdays and weekends.
Challenges in the collaboration with other departments, weekdays and weekends.

Background: Studies have shown that acute patients admitted to hospitals during weekends experience worse outcomes than those admitted on a weekday (i.e. 30-days mortality, length of stay and number of adverse events – a so call weekend effect). However, it is unclear why these variations occur. This study explores how the collaboration between the emergency department and the other departments at the hospital is organized weekdays and weekends, and whether the changes and challenges in the collaboration can explain the existence of the weekend effect.

Methods: The study is a prolonged 6-months ethnographic study. Fieldwork consisted of app 700 hours of participant observations in an emergency department, 25 in-depth interviews with nurses, physicians, secretaries and the management of the department, and four focus groups with four nurses in each group. The empirical material was generated in autumn 2015 and spring 2016 in a medium-sized regional hospital located in Denmark.

Results: In order to provide sufficient care and treatment for in-coming patients, emergency departments are highly dependent on the other departments at the hospital. The results of this study identified different challenges due to the way the collaboration between the emergency department and the other departments at the hospital are organized weekdays and weekends. These challenges includes: 1) Work-procedures: the different ways the specialists from other departments are working in the emergency department. 2) Communication and coordination: the communication and coordination within the emergency department and between the departments. 3) Control: The emergency department's inability to control how the physicians from the other departments are working and prioritizing the task within the emergency department. Challenges, which needs the management’s attention.

Conclusion: The findings showed that the collaboration between the emergency department and the other departments are organized in different ways, some physicians are ‘insourced’ in the emergency department, while other tasks are ‘outsourced’ to other departments but solved within the emergency department. The way the collaboration is organized results in different challenges, especially coordination challenges. These challenges can be possible explanations of the existence of the weekend effect in the emergency department.


Iben DUVALD (Aarhus C, Denmark)
08:30 - 17:40 #11479 - Characteristics of patients treated with NIV in different age groups: preliminary data from the INVENT study.
Characteristics of patients treated with NIV in different age groups: preliminary data from the INVENT study.

INTRODUCTION

Non Invasive Ventilation (NIV) is widely used in European Emergency Departments (ED) to treat acute respiratory failure (ARF). Increasing age of patients presenting to the EDs has lead to an increase of non invasive versus invasive treatments, thus incrementing the number of patients undergoing NIV. In our study we aimed to describe the differences between patients presenting to the ED and needing NIV with regards to age group.

METHODS

We used a database of an ongoing study sponsored by the Italian Society of Emergency Medicine (SIMEU) study group including all patients receiving NIV in the ED of 19 different hospitals in Italy (the INVENT study). Data were collected during 7 periods lasting one week from May 2015 to February 2017, 1 period for every season. Patients were allocated to 4 different groups depending on age: 18-44 years (group 1), 45-64 years (group 2), 65-79years (group 3), ≥ 80years (group 4).

RESULTS

We collected data from 244 patients. The prevalence of patients undergoing NIV increased with age group: 7 in the 18-44y group (2,9%) vs 41 in the 45-64y group (16,8%) vs 93 in the 65-79y group (38,1%) vs 103 in the ≥ 80y group (42,2%).

There was no difference in the etiology of the ARF (acute cardiogenic pulmonary edema, acute exacerbation of chronic obstructive pulmonary disease, pneumonia, neuromuscular disease) between the age groups. 

There were no significative differences in Body Mass Index, HCO3 levels, arterial pO2 and pCO2 pressure, pH, lactate and Kelly scale values between groups. 

While most of the patients were admitted to Acute Care Medicine wards after the ED (66,7%, 63,6%, 62,7%, 69,2%), there was a higher incidence of Intensive Care Unit admission during hospital stay in the first group (42,9% vs 17,5% vs 12,1% vs 3,9% p 0,001).

While there was a higher incidence of intubation in the first group (28,6% vs 14,3% vs 4,3% vs 3,6% vs 6,9% p0,04), there was at the same time a trend to lower mortality in the same group (0% vs 17% vs 19,4% vs 24,3% vs 20,5% p 0,143). 

The rate of Do Not Intubate (DNI) orders increased in age groups from 14,3% (group 1) to 37,6% (group 4), p 0,04.

CONCLUSION

In our study patients with age ≥ 65years represents 80,3% of the population and 42% of patients were over 79 years old. While our data show a higher ICU admission and intubation rate and a lower number of DNI orders within younger patients, there was no difference in etiology, mortality, physiologic values and NIV failure rates between age groups.


Dr Andrea DUCA, Dr Stella INGRASSIA (Milano, Italy), Emanuela BRESCIANI, Francesco PANERO, Daniele CAMISA, Gianfilippo GANGITANO, Patrizia CUPPINI, Maria CARBONE
08:30 - 17:40 #11341 - Chest pain and bedside echocardiography by emergency physicians.
Chest pain and bedside echocardiography by emergency physicians.

Purpose: Echocardiography is a non invasive diagnostic technique that uses ultrasound waves to create images of the heart. It is comprised in training programs in ultrasound medical emergency of prestigious international scientific societies, such  as WINFOCUS (World_Interactive_Network Focused_on_Critical_Ultrasound), and the American College of Emergency Physicians (ACEP). The current scientific evidence supports the use of echocardiography by emergency physicians for its speed, agility and safety for the patient.

Material & Method: Case study of the diagnosis of an interventricular communication as mechanical complication of anterior septal myocardial infarction, using echocardiography performed by Emergency Physician (EP). We used a Sonosite M-Turbo, P21 probe of between 1 and 5 MHz, and echocardiography software.

 

Results: 85 year old female, obese, hypertense and diabetic, with poor quality of life, attended at emergency room for oppressive chest pain with several days of evolution, presenting sickness, sweating, tachycardia and severe hypotension (70/30). Showing an ECG with ST segment elevation with Q wave formation in the precordial leads (V1-V6). The EP performed a bedside echocardiography, observing a discontinuity at the level of apical interventricular septum with left-right shunt and dyskinesia at medium-apical septum and anterior akinesia, fully compatible with the anterior myocardial evolved, with break septal… a postinfarct interventricular communication. Given this findings and her quality of life, the patient wasn´t sent to have an urgent catheterization, starting with sedation and analgesia. She finally died after 24 hours of arrival at the hospital.

Conclusions: Incorporating emergency echocardiography lowers the overall service time, since the emergency physician can be more effective, efficient and dynamic when  handling "time-dependent" emergencies, providing greater clinical patient safety. Unfortunately, in this case the patient could not benefit from curative treatment, but avoided echocardiography to undergo unnecessary interventionism, which would not have prevented the fatal outcome.


Francisco LUQUE SÁNCHEZ (Seville, Spain), Alberto Ángel OVIEDO-GARCÍA, Margarita ALGABA-MONTES
08:30 - 17:40 #11320 - Chest pain and safe discharge of a hospital emergency service.
Chest pain and safe discharge of a hospital emergency service.

INTRODUCTION

The chest pain units (CPU) has been developed to perform a  rigorous assessment of patients with chest pain in the Emergency Department (ED) and can be safely discharged from the hospital or admitted if the presence of acute coronary syndrome is confirmed.

AIM AND METHOD

 We performed a retrospective study of patients with chest pain suggestive of ischemic heart disease and negative complementary tests discharged from the emergency department during the first 6 months of CPU implantation, in a fourth level hospital in Spain.

During this time, 52572 patient adults were attended in the ED.  1577 presented with chest pain and 58 of them were discharged with the diagnosis of doubtful chest pain for ischemic heart disease and an exercise testing was requested.  In the next 24 hours, 43  of them were done.

RESULTS

There were 44 males (76%) and 14 females (14.24%).  The average age was 62.08 years (Rank 37-84). 9 of them were under 45 years of age, 30 were between 45 and 65 years of age and 19 were over 65 years of age.

28 patients had Hypertension, 13 had Diabetes Mellitus, 22 had Hypercholesterolemia and 13 had a history of ischemic heart disease. 

Thrombotic risk scale HEART was calculated for all patients:  33 had a low risk, 24 moderate risk, and 1 high risk.

44 exercise testing were negative, 8 were positive and 6 were doubtful or inconclusive. In this 14 patients,  Computed Axial Tomography was done and all of them were negative.

Exercise testing was negative in all patients under 45 years old, in 86.70% between 45-65 years and in 79.00% of over 65 years old.  All of them had low or moderate Heart scale. Six of the eight positive exercise testing had a moderate HEART.

43 males (96.90%) and 11 females (78.50%) had negative exercise testing and all of the patients with a negative test had ≤ 2 Cardiovascular risk factors.

Finally, 49 people were discharged definitively and 9 were admitted to the Cardiology service to continue being treated.

CONCLUSIONS

Our study shows that the patients assessed in a CPU with low or moderate thrombotic risk can be safely discharged to their home provided that they can be evaluated by an exercise test in the following hours after discharge.  Nevertheless, we emphasize the importance of a good evaluation of the patients with chest pain in the ED. More studies are necessary for evaluating the cost-effectiveness of these units

 

 


Rosario PEINADO CLEMENS (BADAJOZ, Spain), Rocío DOMINGUEZ MAQUEDA, María Del Carmen GARCIA CÁCERES, Gemma MONTERO MILANES
08:30 - 17:40 #11426 - Chest pain as admission symptom: analysis of urgencies, treatment processes and final diagnoses.
Chest pain as admission symptom: analysis of urgencies, treatment processes and final diagnoses.

Background. Chest pain is one of the most common presenting complaints in the emergency department and the underlying diagnosis is usually not acute. However, missing a diagnosis such as acute coronary syndrome (ACS) has potential for significant morbidity and mortality. 

Methods. Data was collected from Jorvi Hospital, one of the adult emergency departments (ED) of Helsinki University Hospital, Helsinki, Finland. We analyzed data from the Uranus patient information system of total 54174 adult patients admitted to Jorvi ED during year 2015. Parameters were patients age, sex, arrival and exit time, ICPC2 symptom, ICD-10 diagnosis, post-discharge location. In Jorvi, symptoms are recorded systematically during triage using ICPC2 coding and diagnoses using ICD-10 coding. A three-level urgency classification is used in the ED: emergency patients must be assessed by a physician immediately, urgent ones within 30 minutes and non-urgent patients within an hour from admission to the ED. Plasma troponin T exclusion protocol is used for patients with clinical suspicion of ischemic cause due to either symptoms or ECG. 

Results. Chest pain (n=1970, 10%) was the third most common presenting symptom among internal medicine patients (n=20173). Mean age of chest pain patients was 61.9 years (SD 18.2), female 49%. The diagnoses behind chest pain symptom were classified as ischemic, other cardiac, and unspecific. The ischemic causes consisted of myocardial infarct (MI) without ST-elevation (STE) in 6%, atherosclerotic heart disease in 3%, unstable angina in 2%, and STEMI in 1%. Atrial fibrillation was the most common other cardiac cause, 6%. The most common diagnosis was unspecific chest pain, in 43%, which includes e.g. musculoskeletal causes. Only 3% of all patients were classified as emergency patients, 58% were urgent and 39% were non-urgent. 88% of all patients, and especially 96% of urgent patients were bedridden. 19% of ambulatory patients were classified urgent and 81% non-urgent. 66% of the patients were discharged home. The most probable patients to be sent home were the sitting, ambulatory patients as well as non-urgent patients, of whom 94% and 75% were discharged home. Four patients died in the ED, one was emergency and three were urgent patients.

Conclusion. Chest pain is a common presenting symptom in the ED. Its specific cause remains often open after excluding ischemic or other cardiac causes. The proportion of non-STEMIs, STEMIs, and other ischemic causes is considerably high. Few patients are considered emergency cases, whereas most patients are bedridden, urgent ones. Most of the non-urgent, ambulatory patients can be discharged home. This underscores the need for careful triage, assessment and monitoring of the patients in order to get the correct diagnosis quickly and start adequate treatment early.


Janne PIHLAJAMAA (HELSINKI, Finland), Maaret CASTRÉN, Veli-Pekka HARJOLA
08:30 - 17:40 #11711 - Chest pain: ACS? Traumatic thoracic aortic rupture resulted from minor injury: an uncommon case report.
Chest pain: ACS? Traumatic thoracic aortic rupture resulted from minor injury: an uncommon case report.

Introduction: Traumatic injuries may affect any parts of the body, including the brain, the extremities and internal organs. The severity can range from minor to life-threatening. Traumatic thoracic aortic rupture is a highly lethal injury and also a common cause of sudden death after a high energy trauma.

Case Report: This 71-year-old man was sent to our emergency room by ambulance because of a motor-vehicle accident. He sat on the road while ambulance arrived. After undertaking a primary survey, his condition was stable. The patient was alert and cooperative, complaining of mild epigastric fullness and painful submandibular wound. Fast focused assessment with sonography for trauma( FAST) was performed, which showed negative findings. Minimal SDH was diagnosed over CT imaging. However, the patient complained of chest pain about 10 minutes later. At that time, his vital signs were stable, and repeat FAST showed minimal left pleural effusion, but no obvious ascites. Then, CT of chest, abdomen and pelvis with contrast medium administration was performed and revealed aortic arch rupture with hemomediastinum and left hemothorax. Then, cardiac surgeon was consulted and emergent thoracic endovascular aortic repair( TEVAR) was performed. The patient’s condition improved after surgery, and he was discharged smoothly about 1 month later.

Discussion: We reviewed the literature of traumatic thoracic aortic rupture. Our case presented with delayed chest pain after a minor trauma. Emergency physicians should be aware of the possibility of aortic rupture in survivors of automobile crashes. A high index of suspicion and prompt management should avoid catastrophic outcomes.


Pei-Shan WU (ROC, Taiwan), Yi-Kung LEE
08:30 - 17:40 #11639 - Chilaiditi Syndrome.
Chilaiditi Syndrome.

Introduction

A Radiologist, Demetrius Chilaiditi reported three cases of colonic interposition between the liver and diaphragm about a century ago.  It was described as a incidental radiological finding. Chilaiditi syndrome refers to a medical condition in which a Chilaiditi sign is accompanied by clinical symptoms. Incidence of Chilaiditi Syndrome has an incidence of 0.025-0.28%.

Variations in normal anatomy can lead to the pathological interposition of the colon between the liver and diaphragm. Anatomic distortions can also result from functional disorders such as Cirrhosis, diaphragmatic paralysis, chronic constipation and chronic lung disease. Chilaiditi Syndrome could be a rare cause of intestinal obstruction, volvulus of caecum, splenic flexure or the transverse colon.

Chilaiditi Syndrome usually presents with abdominal pain, nausea, vomiting and constipation fallowed by respiratory distress and less frequently angina like chest pain.

Chilaiditi interposition (Chilaiditi Sign) is defined by the presence of air below the right diaphragm on a x-ray. The right hemidiaphragm must be elevated, the bowel must be distended and superior margin of the liver must be depressed below the level of the left hemidiaphragm.

Case Report:

A 72 year male was treated by his General Practitioner for vague abdominal pain for four years and was thoroughly investigated. His blood tests were found to be normal as was colonoscopy. CT scan of abdomen was normal except a non obstructed inguinal hernia was noticed, which did not appear to be the cause of pain. Six weeks later the patient developed increasing shortness of breath which was thought to be due to congestive heart failure. A chest x-ray was organised which showed Chilaiditi sign. A diagnosis of Chilaiditi Syndrome was made and he was treated symptomatically. Bowel decompression improved his breathing problem.


Mohammad ANSARI, Ahmad ISMAIL, Pankaj KUMAR (BIRMINGHAM, United Kingdom), Ahmed AMMAR
08:30 - 17:40 #11465 - Chronic abuse of ergotamine.
Chronic abuse of ergotamine.

INTRODUCTION

We present the case of a 52-year-old woman, active smoker, who had several episodes of acute ischemia in extremities due to chronic abuse of ergotamine as a treatment for migraine. She was received in our emergency room with a typical chest pain that appeared at rest with 10 minutes of duration, stopped by the intake of oral nitroglycerin.

CASE DESCRIPTION

She showed haemodynamic stability during all the time, with symmetric periphera pulse. On the ECG of the ambulance they could be seen negative T waves in V1-V4 and depression of the ST segment in V3-V4 with normalization of the abnormalities without pain.

As the blood test showed high troponins, she went under preferential catheterization next day finding an occlusion in the circumflex coronary artery so a pharmaco active stent was placed, being the diagnosis of NSTEACS.

 

DISCUSSION

Considering the chronic abuse of ergotamine in our patient the differential diagnosis was made between a case of ergotism and a NTSTEACS. The ergotism was described for the first time in the IX century, called by the time Saint Anthony´s Fire; subjects who consumed infected cereal by the claviceps purpurea fungus, a parasit fungus with a miceli rich in ergotamine, suffered from acute extense inschemia with autoamputation, convulsions and even death by asfixia. The ergotamine is an alkaloid with central sympatholytic action and peripheral constrictor action thanks to irreversible joints with adrenergic and serotoninergic receptors. Acute ischemia is seen under chronic abuse, by the intake of more than 26 mgr. per week, with an incidence of 0,001%. The most common symptom is ischemia in extremities, being cardiac ischemia highly rare.

A differential diagnosis was made within Prinzmetal´s angina due to the alteration in the ECG and the characteristics of our patient since is a pathology more common in medium age women who suffer from other vasospam phenomenons (migraine in this case) that appears at rest and which changes in the ECG are transitory.

The diagnosis of ergotism is made mainly with the anamnesis which needs to be complemented with image exams. The treatment is made by the discontinuation of the drug and the use of vasodilators like calcium channel blockers. The consume to avoid complications must not exceed 4 mgr per day or 10 mgr. per week. If the consume was chronic it may take months to recover, being necessary the use of anticoagulations according to most of the authors.


Natalia SÁNCHEZ PRIDA (Madrid, Spain), Gema RODRIGO BORJA, Maria CLEMENTE MURCIA, Laura CASTRO REYES, Luz Tamara VÁZQUEZ RODRÍGUEZ, Carlos RUBIO CHACON, Eva FERNÁNDEZ MURO DE PINEDO, Laura SANTOS FRANCO
08:30 - 17:40 #10652 - Chronic pulmonary thromboembolism without pulmonary hypertension.
Chronic pulmonary thromboembolism without pulmonary hypertension.

Acute pulmonary thromboembolism is a condition in which there is a near-total resolution with minimal residual abnormalities although a minority of patients will develop chronic thromboembolic pulmonary hypertension (CTEPH).

We present the case of a 56 year old woman who presented to the emergency department referring thoracic oppression and dispnoea for the last six months. The patient had been diagnosed with a superficial thrombophlebitis three months ago, treated with NSAIDs and prophylactic doses of low molecular weight heparin (for 10 days), improving both, the respiratory symptoms and thoracic oppression. She came back because her symptoms had returned.

Her vital signs were blood pressure of 150/90 mmHg, cardiac frequency of 60 bpm, oxygen saturation of 98%, respiratory frequency of 18 rpm. Physical examination was normal at the time. Blood test were performed, the results were normal. A study of hipercoagulability was performed and it was positive for protein S 100%, protein C 70% and antithrombin 91%. A pulmonary gammagraphy was also performed and it was compatible with a chronic pulmonary embolism. An echo-cardiogram was performed and it showed normal systolic function of left autrium. Ejection fraction >55%. No signs of pulmonary hypertension.

The patient was diagnosed with a chronic pulmonary embolism without pulmonary hypertension and was treated with low molecular weight heparin for seven days, then started with acenocumarol. At this time she remains with the treatment and on periodic follow up with the pneumologist in order to monitor the pulmonary pressure.

Pulmonary embolism is defined as the occlusion of one or more branches of the pulmonary arteries, caused by the movement of thrombi from the deep vein system. Despite the fact that most patients that survive it, have a clinical resolution, in some cases it is not resolved and large segments of the pulmonary artery tree are occluded by the thrombi. Consequently there is an increase in resistance which helps develop pulmonary hypertension. Pulmonary hypertension is defined by a mean pulmonary arterial pressure (mPAP) ≥25 mmHg at rest. Patients with untreated CTEPH are likely to develop progressive disease and have a high risk of dying from right heart failure. Clinical manifestations often include dypnoea and exercise intolerance in the early stages, as the course of the disease progresses patients may present with thoracic pain, syncope or hemoptysis. The first step in the management is anticoagulant therapy. It is initiated using intravenous unfractionated heparin or subcutaneous low molecular weight heparin. Once they are fully anticoagulated they can be transitioned to an oral anticoagulant. The next step is to evaluate a pulmonary thromboendarteretomy which is both the surgical procedure of choice and the definitive therapy.

Bibliography

Fedullo P, Kerr KM, Kim NH, Auger WR. Chronic thromboembolic pulmonary hypertension. Am J Respir Crit Care Med 2011; 183:1605.


María Del Pilar CARLOS GONZÁLEZ (santander, Spain), Magdalena FERNÁNDEZ GARCÍA, Noelia SANTOS MÉNDEZ, Valentina ACOSTA RAMÓN, Marta BÁSCONES GARCÍA, Marta PASTRANA FRANCO, Ascensión JORRÍN MORENO
08:30 - 17:40 #10673 - Clinical Audit of Clostridium Difficile Management.
Clinical Audit of Clostridium Difficile Management.

See attached file for abstract 

Characters 2982 including spaces


Rushabh SHAH, Raajul SHAH (London, United Kingdom)
08:30 - 17:40 #11077 - CLINICAL MANIFESTATIONS IN ASEPTIC MENINGITIS IN WEST MALAGA.
CLINICAL MANIFESTATIONS IN ASEPTIC MENINGITIS IN WEST MALAGA.

BACKGROUND

Aseptic meningitis is usually diseased observed in the emergency room. Clinical characteristics of meningeal syndrome are not present for all patients. There are reports of increase of lymphocyte meningitis during the summer period.

OBJECTIVES

Describe the clinical, analytical, and seasonal characteristics more common in aseptic meningitis in West Malaga.

MATERIALS AND METHODS

Patients admitted in the emergency room and after that in Neurology, with a final diagnosis of aseptic meningitis from the year 2014 to 2016, were included. It was analyzed retrospectively symptomatology, socio-demographic characteristics, blood, cerebrospinal fluid analytical and microbiological test. Possible complications were evaluated non-encephalitic and the frequency of treatment.

RESULTS

55 patients met criteria; 52% male, 48% female; with mean age of 35±16 years. 

38% of cases were in the months of July, August and September. The average temperature was 37.9 ° Celsius.

23.6% of cases had previous infectious signs. 24 cases (43.6%) showed meningeal signs, only 6 (10.9%) altered level of consciousness and 52 cases (94.5%) headache. 

Biochemical analysis of cerebrospinal fluid showed mean values 205 leukocytes/mm³, 60.7% mononuclear cells predominance. 

Idiopathic meningitis was happen in 82% cases.

Viral Polymerasa Chain Reaction (PCR) was positive in 18% due to enterovirus infection (4% of them), herpes simplex virus type 2 (12% of them) and varicella and herpes zoster (2% of them). 

Antiviral treatment was administred in 16% of patients. The average time was 7,2 days.

There was complications on 18 patients (32.7%) as puncture headache. Only two cases presented a seizure during hospital admission without symptomatic epilepsy after follow-up and after withdrawal of antiepileptic drugs.

CONCLUSIONS

In aseptic meningitis, headache and fever are the most frequent symptoms, not so much the signs of meningeal irritation. The most frequent etiology is idiopathic followed by viral infection, with an increase of cases in the summer period. The aseptic meningitis in our setting  has similar clinical characteristic to previously published data.


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Blanca SÁNCHEZ MESA, Alejandro GALLARDO-TUR, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11656 - Clopidogrel related spontaneous spinal epidural haematoma (SSEH): complete recovery with conservative management.
Clopidogrel related spontaneous spinal epidural haematoma (SSEH): complete recovery with conservative management.

Background: To raise awareness of SSEH as a possible occurrence in patients on anticoagulation.

Case Report: We report a case of Spontaneous Spinal Epidural Haematoma (SSEH) in a 92 year old female who presented with profound bilateral lower limb weakness preceded by sudden onset severe low back pain.  She was on low dose clopidogrel for secondary stroke prevention. Neurologic examination revealed flaccid lower limb paraplegia with MRC Grade I muscle power on left and Grade 2 on right hip and knee flexors, with loss of anal sphincter tone. Loss of all sensory modalities were documented L3 downwards. MRI of spine showed a lesion extending from T5 to L3 in keeping with haematoma with critical compression and flattening of the distal cord at the level of the thoracolumbar junction. The case was discussed with neurosurgeons and was decided for conservative management.  Her mobility improved significantly soon after admission and she could manage to walk after few days. Later on she was discharged home.

Discussion and conclusion: Spontaneous Spinal Epidural Haematoma (SSEH) is a rare but disabling entity which can present with the features ranging from simple back pain with radiculopathy to complete paraplegia or quadriplegia depending on the site and severity of the compression. SSEH has been reported in association with coagulopathies, anticoagulant therapy, blood dyscrasias, pregnancy and vascular malformation. This case is interesting because to our knowledge, no more than five cases of clopidogrel related spinal epidural haematoma have been reported in the literature with our patient being the eldest. Moreover among those cases, present case is the only example that did not require any surgical intervention. With the popularity of clopidogrel in the management of cardiovascular and neurological pathologies, physicians should be aware of the remote risk of a spontaneous spinal epidural haematoma that may cause permanent neurological damage.


K M Iqteder UDDIN (Bury St, Edmunds, United Kingdom), Srijeeb DAS
08:30 - 17:40 #11939 - Comparative study about the management of acute cystitis between primary care and hospital emergency in an urban sanitary area of Madrid.
Comparative study about the management of acute cystitis between primary care and hospital emergency in an urban sanitary area of Madrid.

Acute cystitis is a frequent infectious pathology. It can be diagnosed and treated in differents areas like primary care and the hospital emergency. It has been suggested that there are differences in the medical-therapeutic management in relation to primary care with emergencies, with a hypothetical greater use of complementary tests and inadequate antibiotics in the latter.

We suspect that there are differences in the use of diagnostic and therapeutic methods in our healthcare environment in primary care hospital emergencies, as well as differences in diagnosis and treatment of ITU, depending on the health resource requested. With this hypothesis we analyzed the diagnostic procedures and the treatments were performed by the primary care physicians compared to the emergency physicians in our hospital area thus representing a public health problem because of the problem of resistance as well as a possible repercussion Economic costs for the health Costs they represent.

The cost to arrive at a correct diagnosis would be greater in the hospital facilities than in the primary care centers given, among other things, the greater number of complementary tests to reach the same diagnosis.

Performing a good medical history can minimize the number of complementary tests and nevertheless, reach a certain diagnosis. It can be reached at the same time and receive 3 or more symptoms with a probability of treatment accurate around 90%. In case of simple to collect 2 symptoms with a strip of urine optimizes the diagnosis and the similar percentages obtaining an optimal treatment in more than 80% of the cases.

The most prevalent microorganism in our population is E. coli. The recommendations of the antimicrobial treatment are based on the data of sensitivity of E. coli, being the urinary pathogen more frequent. Bacterial resistance is not always associated with treatment failure. Rates of E. coli resistance to amoxicillin-clavulanic are less than 10% in our community and are considered the treatment of choice for uncomplicated UTIs. It is also active against Enterococcus faecalis and Proteus mirabilis. 

With the study performed, even with the losses obtained, we can say that the study populations are similar. In the two comparable populations, it has been seen that the diagnosis and treatment are performed in a similar way, except for the request of urine cultures that is best performed in primary care

It is interesting to propose formative cycles and protocols in both media for a better diagnostic-therapeutic optimization, independently of the health resource in which the consultation is carried out to obtain a correct diagnostic-therapeutic procedure close to 100%. It would be important to follow the guidelines available to optimize care and avoid unnecessary costs, since the percentage of times when the clinical guidelines on urinary tract infection were followed (around 25.6% in the emergency department while in Primary care in 34.8%).


Miriam UZURIAGA MARTIN (Madrid, Spain), Carlos HERNANDEZ, Vanesa Natalia ISAAC, María PÉREZ SOLA, Elba GARCIA, Lara UZURIAGA MARTIN, Rodrigo PACHECO PUIG, Juan Jose FERNANDEZ DOMINGUEZ
08:30 - 17:40 #11817 - Comparison of patient expectations and patient-experience during a visit in the Emergency Department.
Comparison of patient expectations and patient-experience during a visit in the Emergency Department.

Introduction

Managing patients expectations in the Emergency Department (ED) environment is challenging for every physician and compliance with recommended therapies is known to be better when patient satisfaction is higher. This study was undertaken to compare attents and realisations of  patient experience during their consultation in an urban ED, and their influence on patient global satisfaction.

 

Methods 

We present here a monocentric and prospective study in the Emergency Department of a French teaching hospital. Patients expections and satisfaction before and after ED consults was assessed on during different 8-hours periods that covered the all-day time.

 

Results

During the 10-days study period, 184 on-site questionnaires were submitted to all patients admitted in the ED and capable to respond, before and after the medical consultation. A total of 106 patients  were finally included. 78 patients were non-respondant, 38 refused to participate and 40 were lost of sight. Among the 106 patients included, 70 expected benefit of a complementary exam (radiology, biology, electrocardiogram) but 82 effectivelly had one. Global satisfaction differed between the day of week (with a highest satisfaction during business days (p< 0.05)), or the time of the day (highest satisfactaction during deep night (p< 0.05)). Global satisfaction was also significantly lower when the patients were not adressed by another physician (p<0.05), or when the degre of perceived emergency was high (p<0,05). A difference between patient expectations and effective realisation of complementary exams had no influence on patient global satisfaction (7.89/10 vs 7.86/10 ; p=0,92). In the same way, a difference between patients expectations and concrete realisation of an organ-specialist consultation in the ED (7.79 vs. 7.94 ; p=0,95) had no influence on satisfaction. The analysis of the difference between the expected and real total length of stay had as well no impact on patient satisfaction (p=0.69). Appart from patients who described themselves as «very anxious », a high level of perceived empathy of the Medical Team had a positive and significative influence on patient global satisfaction. The patient-physician relationship is also a crucial issue as patients are significantly more satisfied when an explanation on the level of severity was given (p<0.001), when the physician prooved empathy (Spearman's correlation coefficient: 3.9 ; p=0.001) and when the quality of information at discharge was better (Spearman's correlation coefficient: 3.4 ; p=0.001).

Conclusion

Differences between patient expectations and concrete realisations during a consultation in the ED have no significative influence on patient satisfaction at discharge. Emergency Team’s communication remain as a crucial issue in patient satisfaction in EDs.


Vincent SCHILT, Sarah UGÉ (Strasbourg), Elena Laura LEMAITRE, Luc BILGER, Philippe KAUFFMANN, Claire KAM, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11861 - COMPARISON OF PATIENTS TAKEN IN AN EMERGENCY SERVICE WITH AND WITHOUT PREVIOUS AURICULAR FIBRILLATION THAT NEEDED ACUTE RESTORATION AT SINUSAL RHYTHM.
COMPARISON OF PATIENTS TAKEN IN AN EMERGENCY SERVICE WITH AND WITHOUT PREVIOUS AURICULAR FIBRILLATION THAT NEEDED ACUTE RESTORATION AT SINUSAL RHYTHM.

INTRODUCTION:

Despite the progress in the treatment of patients with atrial fibrillation (AF), this arrhythmia remains one of the most important causes of stroke, heart failure, sudden death and cardiovascular morbidity worldwide.

OBJECTIVE:

To evaluate in patients with and without antecedents of previous Atrial Fibrillation who needed acute restoration to sinus rhythm in the patients who opted for electrical or pharmacological cardioversion and the percentage of effectiveness of both.

MATERIAL OR PATIENTS AND METHOD:

Descriptive, observational and retrospective study in which all patients with a diagnosis of Atrial Fibrillation (AF) were selected from October 1, 2012 to December 30, 2013. They consulted at the Emergency Department of the General University Hospital Reina Sofía de Murcia, To a population of 200,000 inhabitants and 275 urgencies / day.

Variables to study: presence or absence of previous atrial fibrillation, type of CV performed (electrical or pharmacological) and effectiveness of the same.

RESULTS:

During 2012 and 2013, 762 patients were diagnosed with AF in our Emergency Department, of whom 42.26% had a previous diagnosis of AF and 57.74% had no previous diagnosis of AF. Of those who presented previous diagnosis of acute AF, acute restoration to sinus rhythm 34.16% by means of rhythm control. In the case of which electrical cardioversion (CVE) was performed at 60% and at 40% pharmacological cardioversion (FVC). The efficacy was 80% in patients undergoing CVE and 82.35% in FVC. Of the patients with no previous history of AF, acute restoration to sinus rhythm required 20.23% by means of rhythm control, of which CVE was 46.07% and FVC 65.17%, of which the efficacy was 85.37% in patients submitted to CVE and 70.69% to CVF.

CONCLUSION:

- There are no significant differences between the cardioversion method chosen in patients with and without prior AF.

- Approximately more than 75% of patients treated with cardioversion regardless of the type chosen was effective.

 


Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Danae FERNANDEZ-CAMACHO, Blanca MEDINA TOVAR, Blanca DE LA VILLA ZAMORA, Pascual PIÑERA SALMERÓN (montepinar, Spain), Cesar CINESI GOMEZ
08:30 - 17:40 #11804 - Comparison of prognosis between healthcare-associated pneumonia and community-acquired pneumonia in patients admitted to intensive care unit.
Comparison of prognosis between healthcare-associated pneumonia and community-acquired pneumonia in patients admitted to intensive care unit.

Introduction:

Pneumonia developing in patients who receive healthcare services in the outpatient environment has been usually classified as community-acquired pneumonia (CAP). However, recent investigations suggest that this type of infection, known as healthcare-associated pneumonia (HCAP), is distinct from CAP.

The aim of this study was to compare the initial demographic characteristics and prognosis between severe HCAP and CAP patients hospitalized in intensive care unit (ICU).

 

Methods:

Retrospective study over 2-year period conducted in patients with HCAP or CAP patients hospitalized in ICU. Admission pneumonia scores were calculated, and clinical variables were collected. Fischer exact test and T-test were used when appropriate to compare the HCAP group.

Results:

Out of thirty-three patients (sex-ratio=1.5; mean age 68 ± 15 years) who were hospitalized in ICU during the study period, eleven were diagnosed as HCAP and twenty-two as CAP. Among HCAP patients, 45.4% had a history of hospitalization in the last 90 days, 27.3% received outpatient intravenous therapy, 27.3% were on hemodialysis program in the last 30 days. Demographic data including age, sex-ratio were similar in the two groups. Comorbidities were most frequent in the HCAP with p=0.03. The rates of patients with CURB-65 scores of 3 or more (64% vs 68%; p=0.31) and PSI class IV or more (73% vs 73%; p=0.38) were comparable in both groups. Inappropriate empiric antibiotic treatment was documented in 45.5% of HCAP patients versus 18.8% of CAP patients without significant difference (p=0.16). The duration of hospitalization (8.6 ± 8 vs. 5.6 ± 5 days, p= 0.25) and mortality rate (63.6% vs. 63.6%, p=0.64) were similar in both groups.

 

Conclusions:

Severe pneumonia continues to be associated with a considerable burden of disease. Recent studies suggest that HCAP should be distinguished from CAP because of the different clinical features. However, the current definition of HCAP does not appear to be a prognostic for severe presentations and mortality.


Fatma HEBAIEB (Ariana, Tunisia), Eya HNIA, Salah SNOUDA, Nadia AMRI, Ameni SGHAIER, Raja FADHEL, Moez KADDOUR, Nawres BEDOUI, Hassen BEN GHEZELA
08:30 - 17:40 #11122 - Comparison Of Social Supports In Geriatric Patients Who Admitted To Emergency Department For Trauma And Medical Reasons.
Comparison Of Social Supports In Geriatric Patients Who Admitted To Emergency Department For Trauma And Medical Reasons.

Introduction and Aim:Admittances of geriatric population to Emergency Department, which is the main gate of the healthcare system, are increasing day to day. Elderly people need much more social support because of their existing diseases. Therefore, it is important to assess social support levels beside medical conditions of geriatric population. In this study, we aimed to compare social support and stress levels of the patients over the age of 65 presenting with medical problems and traumatic incidents to Emergency Department.

Materials and Methods:Subjects of the study consist of 197 patients admitted to Emergency Department of Ankara Keçiören Training and Research Hospital, T.C. Ministry of Health 2nd Association of Public Hospitals, University of Health Science, between the dates of October 1st, 2015 and April 1st, 2016. Patients who are under the age of 18, with Emergency Severity Index (ESI) 2 and below, stay at nursing home or do not have any caregiver, and cannot speak Turkish were excluded. Data was obtained from a questionnaire that is prepared to determine sociodemographic properties and DUKE Social Support and Stress Scale (DUSOCS). SPSS for Windows® 15.0 (SPSS Inc, Chicago, USA)®statistics software was used for statistical analysis of all the data obtained during the study and recorded on study forms. Value of p<0.05 was accepted as statistically significant.

Results:Patients presenting with medical problems, family support levels are higher than patients presenting with traumatic incidents, and this difference is statistically significant (p=.028). Concurrently, when both groups’ family stress and social stress levels are viewed, patients presenting with trauma have higher levels of stress, and this difference is statistically significant (p<.001). Young-old group had more social support levels than the other two groups (p<.001), old-old group had more social support levels than very-old group (p<.001). Although a negative way, rho= -.280, poor relation is detected between social support and age (p<.05). While family support and social support levels of unmarried patients are lower than married ones (p<.001), correlatively family stress levels are low as well (p=.021).

Conclusion:In our study, we compared social support and stress levels of the patients with 65 years and over patients presenting with medical problems and traumatic incidents, at the Emergency Department and found that patients presenting with trauma have lower social support levels and higher social stress levels.


Tuba SAFAK, Emine EMEKTAR (Ankara, Turkey), Yasir SAFAK, Eda KAN, Seref Kerem CORBACIOGLU, Yunsur CEVIK
08:30 - 17:40 #11264 - Comparison of the Canadian head CT rules, the new Orleans criteria and NEXUS II criteria in patiens with minor head injury.
Comparison of the Canadian head CT rules, the new Orleans criteria and NEXUS II criteria in patiens with minor head injury.

OBJECTİVE. Minorheadtrauma is defined as a bluntheadtraumawithchanges in consciousness, amnesia, anddisorientation in patientswithGlaskowComaScale 13-15. Manypatientsaredischargedwithoutsequelaeafter a certainperiod of observation, some of themmayworsenandneurosurgerymay be needed. Inthemanagement of thesepatients, computerizedtomography is frequentlyusedforearlydiagnosisandtreatment. Clinicaldecisionrulesadoptedtoidentify life-threateningcomplications in patientswithminorheadtraumaaretheCanadaCriteria, New Orleans criteria, andNexus II criteria. Theaim of thisstudywastoinvestigatetheeffects of thetheCanadianCriteria (CCHR), New Orleans Criteria (NOC), theCanadianCriteria (CCHR), andNationalEmergency X-Ray UtilizationStudy II (NEXUS II) criteriaaccordingtothehistoryandphysicalexaminationfindings of patientsadmittedto İstanbul Medeniyet University Göztepe EducationandResearchHospitalEmergency Service betweenNovember 2015 andNovember 2016 formildheadtraumaandtodeterminetheefficacyandsafety of thesethreerules in theuse of emergencyservices.

METHODS.PatientswithGlaskowComaScalescorebetween 13-15 andwhounderwent a head CT examinationwereexaminedprospectivelybetweenNovember 2015 andNovember 2016 in ourstudywith a minorheadtraumafrom İstanbul Medeniyet University Göztepe Training andResearchHospitalAdultEmergency Service. Theage, gender, traumamechanism, GCS score, unconsciousness, amnesia, disorientation, headache, nausea, vomiting, alcohol-drugintake, seizure, coagulopathy, anticoagulantuse, pastmedicalhistoryandphysicalexaminationfindings, , hospitaladmissionrecords of thepatientsincluded in thestudywerenoted. Patientswereevaluated in accordancewiththe NOC, CCHR and NEXUS II guidelines.

RESULTS. Of the 140 patientsincluded in thestudy, 87 weremaleand 53 werefemale. Themostfrequentcause of minorheadtraumawasfoundto be falls. Theprevalence of abnormalhead CT wasfoundto be 45.7%. Retrogradeamnesiaover 30 minuteslong, headache, lethargy, skullfracture, change in vigilancestatusand GCS:13 were of statisticalsignificance in determiningtheoutcome of unusualhead CT. Thesensitivity of the NOC rulewas 87.5%, thespecificitywas 6.57%, thesensitivity of CCHR was 82.81%, thespecificitywas 32.8%, thesensitivity of NEXUS II was 93.75% andthespecificitywas 3.94%.

CONCLUSION.The CCHR rulewasfoundto be morepredictive of pathologic BBT resultsaccordingto NOK and NEXUS II (p = 0.034). Inconclusion, the CCHR rule is thoughttohave a higherclinicalperformance in detectingintracranialinjuries.


Merve KONAR, Kurtulus AÇIKSARI, Onur INCEALTIN, Aykut YUKSEL, Fatma SARI DOGAN, Vehbi OZAYDIN, Mehmet UNALDI (Istanbul, Turkey), Mehmet AYRANCI, Tuce DUZKEL, Pelin ATA, Hasan GUCLU, Didem AY
08:30 - 17:40 #11887 - Comparison of two educational methods, lecturing and simulation, in adherence to ventilator set guidelines among emergency medicine residents in centers related to Iran University of Medical Sciences, 2014.
Comparison of two educational methods, lecturing and simulation, in adherence to ventilator set guidelines among emergency medicine residents in centers related to Iran University of Medical Sciences, 2014.

Abstract

Introduction: Considering improvement in knowledge and rapid changing in medicine, creation of new methods of education is mandatory. Using advanced technology such as computer based softwares and educational movies in curriculums are increasing. The numbers of intubated patients in Emergency Department (ED) are increasing  nowadays and  Ventilator adjustment is one of the important skills and an important responsibility of emergency physicians. Generally speaking, ventilator adjustment is not well performed in EDs and low adherence to guidelines is seen. Among the various methods of education, lecturing is the most prevalent methods but there is increasing evidences that advanced educational methods especially simulation based learning has higher efficacy and learner satisfaction.    

Materials and Methods: An interventional study was designed and performed between the emergency medicine residents of  IUMS. An initial assessment was recorded by some check lists and then the participants were devided randomly in two groups, one lecture based, another one, with an educational video (simulation group). The ventilator adjustment  was reevaluate and compared among two groups.

Results: 33 emergency medicine residents participated in the study. Before presentation of education by the researcher, the correct adjustment rate was 13(40%) and after education, despite type of learning, it raised to 18(54.5%). Incorrect ASB rate was 11(33.3%) which decreased to 6(18.8%) after educational sessions. Incorrect trigger rate decreased from 10(30.3%) to 6(18.18%) with P value < 0.005. In comparing of two methods, the correct adjustment rate was similar and between all variables, just incorrect ASB in simulation group and incorrect trigger in lecture-based group were reported elevated with P value <0.005.

Conclusion: In this study, although ventilator adjustment was improved with education, but there was no difference between two methods of lecturing and simulation-based education. Actually, we can conclude that simulation method could be effective as much as lecturing method.


Hossein SAIDI, Neda ASHAYERI, Dr Mahdi REZAI (Tehran, Islamic Republic of Iran)
08:30 - 17:40 #11181 - Completion time of more than 6 hours in the emergency department: root cause analysis.
Completion time of more than 6 hours in the emergency department: root cause analysis.

Background

Emergency department (ED) crowding is a common international problem and it is negatively affecting the quality and efficiency of ED care. Previous studies worldwide have demonstrated that ED crowding is associated with adverse patient outcomes including increased mortality. No in-depth study has yet been performed to systematically analyse the root causes of a long ED length of stay (ED-LOS) in the Netherlands. The primary aim of this study was to identify the healthcare worker-, organisational-, technical-, disease- and patient- related root causes that may contribute to an increased ED-LOS and formulate recommendations to improve the quality and efficiency of ED care.

Methods

This study is an observational retrospective record review study, in patients visiting the ED of an academic hospital in the Netherlands during one week. Basic data was gathered through the Electronic Patient Dossier (EPD) from all patients. A PRISMA analysis was conducted on patients with ED-LOS of more than 6 hours, excluding children and critical care room presentations. Two medical and PRISMA-trained investigators independently assessed the data and root causes were classified using the Eindhoven Classification Model (ECM). 

Results

568 patients were included and 86 patients (15%) had an ED-LOS of more than 6 hours. Patients with an ED-LOS of more than 6 hours were generally older (mean age 58 versus 41 years), more likely to be treated by internal medicine (40% vs 20%) and surgery (14% vs 7%), needed more consultations (2,5 versus 1,9), more likely in need of hospital admission or transfers (59% versus 29%) and less likely to be discharged from the hospital (40% vs 70%).

A PRISMA-analysis was conducted on 74 patients (88%). 269 Root causes were identified. 216 (78%) Of all root causes were organisational related such as no beds being available for hospital admission, lack of staff for the assessment of radiological images, doctors chart information being available after more than 1 hour, interns doing patient intake or ambulances arriving late at ED for patient transport. 53 (19%) Root-causes were disease related, such as patients in need of extensive radiological imaging, or requiring complex care. Other root causes were less frequent.

Conclusions

This in-depth PRISMA analysis showed that the root causes for a prolonged stay (increased ED-LOS) were mostly organizational and beyond control of the ED. Appropriate measures should be implemented to address these organisational factors in order to reduce ED-LOS and thereby improve patient flow and outcome. 

 


Babiche E.j.m DRIESEN (AMSTERDAM, The Netherlands), Bauke H.g. VAN RIET, Lisa VERKERK, Hanneke MERTEN, Prabath W.b. NANAYAKKARA
08:30 - 17:40 #11043 - Complex appendicitis: Integrating clinical data with Point-of-Care-Ultrasound.
Complex appendicitis: Integrating clinical data with Point-of-Care-Ultrasound.

Background: Appendicitis is a time-sensitive diagnosis with varying presentations. Point-of-care-ultrasound (PoCUS) can be used to rapidly identify it. In children, PoCUS is the preferred initial imaging study because it is non-invasive, rapid, and has no ionizing radiation. Its sensitivity in identifying appendicitis ranges between 83 to 92%. Objective: We present a typical acute appendicitis case, illustrating the sonographic changes encountered with a perforated appendix. Case Report: An eleven-year-old male presented to the emergency department with three days of fever, anorexia, and right lower quadrant abdominal pain with associated vomiting and diarrhea. Pain was described as a non-radiating, stabbing ache, exacerbated by movement and palpation. On physical examination, the patient was tachycardic and febrile. The abdomen was significant for voluntary guarding in the right lower quadrant and suprapubic regions. He had positive Psoas, Obturator, and Rovsing’s signs and expressed discomfort with heel strike. Laboratory findings demonstrated leukocytosis of 21.5 103uL. The emergency physician performed PoCUS, using a SonoSite X-porte Ultrasound machine with curvilinear and high frequency linear transducers. To guide transducer placement, the patient was asked to pinpoint the location of his maximum pain. Anatomical landmarks, including the psoas muscle and iliac vessels, were identified on ultrasound, and graded compressions were performed. Sonographic findings included an appendiceal wall measuring over 10mm with loss of integrity and an adjacent mixed echogenic mass. Free fluid, hyperechoic fat, and thickened bowel loops surrounded the appendix. These findings were highly suggestive of acute appendicitis complicated by perforation and abscess formation. The patient was quickly transferred to a tertiary care facility with pediatric surgery capabilities. The patient underwent Interventional Radiology-guided percutaneous abscess drainage and had an uneventful post-operative course. Discussion: PoCUS is an effective tool in diagnosing complicated appendicitis. Ultrasound findings consistent with a perforated appendicitis include appendiceal wall edema greater than 6 mm with loss of the submucosal layer integrity, presence of hyperechoic peri-appendiceal fat, surrounding free fluid, and adjacent thickened bowel loops. Abscess formation is characterized by a mixed echogenic mass of pus and fecal material. Patient’s body habitus, excessive bowel gas, sonographer inexperience, and atypical location of the appendix are limiting factors in PoCUS appendix evaluation.


Andrew VUCELIK MD, Katharine BURNS MD, Reed ANDREWS MSII (Morgantown, USA), Stephen DAVIS MPA MSW, Kristine ROBINSON MD
08:30 - 17:40 #11590 - Comprehensive Life Support: Superior outcome in out-of-hospital cardiac arrest by improving the whole Chain of Survival.
Comprehensive Life Support: Superior outcome in out-of-hospital cardiac arrest by improving the whole Chain of Survival.

Background

Out-of-hospital cardiac arrest (OHCA) is associated with high mortality and a favorable outcome is lower than 10 % in most regions worldwide. Favorable outcome strongly depends on all parts of the so called Chain of Survival and seems to be influenced by multiple factors. For this reason we established a concept of comprehensive life support improving all links of the chain of survival in OHCA in order to increase the survival with favorable outcome.

Methods

Since 2012 a comprehensive life support concept (CLS) was established in a county with 252,000 inhabitants and a two-tiered physician-staffed EMS-system. CLS included: 1. Protocol-based EMS dispatch; 2. Telephone CPR instructions; 3. Implementation of a first-responder system; 4. Certified ALS-training and structured team-feedback in EMS; 5. Protocol-based post-resuscitation-care in a single university hospital cardiac arrest center. Incidence and outcome following OHCA was compared between 2009-2011 (control) and 2014-2016 (CLS intervention) (Chi-square testing). Incidence was calculated to 100,000 inhabitants/year, neurological favorable outcome was defined as Cerebral Performance Category (CPC) 1or 2.

Results

Control vs. CLS: CPR attempts n=577 (76.4/100,000 inhabts/yr) vs. n=670 (88.7/100,000 inhabts/yr), n.s.; mean age 67,9(±16,4)yr vs. 69(±16,6)yr, n.s.; admission with return of spontaneous circulation (ROSC): n=225 (29.8/100,000 inhabts/yr) vs. n=276 (36.5/100,000 inhabts/yr), n.s.; discharged alive n=75 (9.9/100,000 inhabts/yr) vs. n=121(16/100,000 inhabts/yr), p=0.014; neurological favorable outcome n=49(6.5/100,000 inhabts/yr) vs. n=86(11.4/100,000 inhabts/yr), p=0.018.

Conclusion

Comprehensive life support (CLS) as a concept of optimizing all links of the chain of survival including protocol based dispatch and CPR instructions by EMS dispatch center, first-responder system, certified ALS-Training with structured team feedback in EMS and post-resuscitation care in a cardiac arrest center lead to better and remarkable high rates of survival in OHCA.


Clemens KILL (Essen, Germany), Erich WRANZE, Maik KLEIN, Heiko HARTMANN, Sven SCHMIDT, Konstantin KARATOLIOS, Birgit MARKUS, Birgit PLOEGER, Martin SASSEN, Susanne BETZ, Jens Holger FIGIEL, Barbara CARL, Bernhard SCHIEFFER
08:30 - 17:40 #11635 - Conclusions of seven years of unconscious Emergency Calls.
Conclusions of seven years of unconscious Emergency Calls.

Background
SMURD (Mobile Emergency Service for Resuscitation and Extrication) is the top emergency service in Romania. During the last seven years, SMURD Sibiu Mobile Intensive Care ambulance was sent to more than eight thousand requests, reporting an emergency case involving what was reported by the caller to be an unconscious patient. In such situations, the local emergency medical dispatcher sends the best unit available (having a doctor and a team of paramedics on board fully equipped) to deal with the case but too often it finds out that this is not the unconscious case they expected. Unfortunate correct dispatching affects the outcome of prehospital procedures.

Methods
More than 8000 cases reported as unconscious emergencies were included in the study. Data was obtained retrospectively from Sibiu SMURD (Mobile Emergency Service for Resuscitation and Extrication) between 01.01.2010 and 01.01.2017. From a total cases, it has been selected only the unconscious ones dispatched to SMURD Sibiu MICU. We have collected the medical details of the case (patient medical status when team arrived, GCS (Glasgow Coma Scale), presumptive diagnosis, medical procedures taken) and the reason for the emergency call.

Results
From a total cases reported as unconscious emergency in 56% cases the patient was conscious and 44% was the unconscious case expected. Analyzing this phenomenon against segments of 6 months it has been revealed a positive trend from first year to the last year of unconscious patients found in unconscious alarms a possible result of general population BLS training of Sibiu inhabitants.

Unconsciousness against pathology type of the cases is looked at. The best recognition rate was found in cardiopulmonary arrest with a value of 98% , followed far behind by surgical conditions 48%, and a]trauma cases having a value of 17%.

Ambulance Type C and ambulance Type B ROSC(Return of spontaneous circulation) rate in CPR maneuvers are compared. From a total of CPR cases for Type C ambulance responses, the average ROSC rate is 26% comparing with type B CPR cases average rate of 6% from a total of cases dealt with. CPR cases are split by cardiac arrest type: ROSC rate (Asystole 19% <> 1%, VF/pulseless VT 43% <>20%, PEA 30% <> 0%) .

Conclusion
Calls reported as “unconscious” are more likely to occur when the callers are not properly educated about knowing the difference between a conscious and an unconscious patient. For the situation when the information collected is not accurate we may face the following:
a. worng life saving measures are taken for the patient
b. wrong first procedures are chosen in case of emergency


Marius SMARANDOIU (Sibiu, Romania), Alin CANCIU, Daniela TARAN, Dania LUNCA, Denisa FALAMAS
08:30 - 17:40 #11927 - Congenital diaphragmatic hernia presenting with bowel obstruction in an elderly patient.
Congenital diaphragmatic hernia presenting with bowel obstruction in an elderly patient.

A 91 year-old woman presented to our Emergency Department with 24 hours of epigastric abdominal pain and bloating, as well as vomiting. She had a history of hypertension, chronic anaemia and asthma, with no abdominal surgeries. No diarrhoea or constipation were reported, nor chest pain or shortness of breath. On physical examination, she had a distended abdomen with epigastric tenderness, and non-pathological stool on digital rectal examination. Blood  tests showed neutrophilia with no leucocytosis. Abdomen and chest X-Rays suggested abdominal content in the chest, consistent with diaphragmatic hernia (Morgagni hernia). A CT chest-abdomen was performed, confirming a retrosternal 45 mm diaphragmatic hernia containing transverse colon, as well as signs of retrograde large and small bowel obstruction. The patient was referred to the General Surgery department and underwent a laparoscopic hernia repair with no bowel resection. She was discharged on post-operative day 4 with no further complications. Conclusion: Morgagni hernia is an uncommon condition, most of the cases being reported in children. Still some cases can present in elderly people with symptoms due to complications such as volvulus, haemorrage, bowel perforation or incarceration/strangulation. It is imperative to make an accurate and expedient diagnosis, as most of these complications require emergency surgery.


Carlos RUBIO CHACÓN (Madrid, Spain)
08:30 - 17:40 #11667 - Constipation as a first sign of abdominal aortic aneurysm.
Constipation as a first sign of abdominal aortic aneurysm.

Intoduction:

Abdominal aortic aneurysm is discovered incidentally during an exam for other diagnostic purposes. Clinical manifestations depend on associated complications, most commonly rupture or dissection. Therefore, A thorough clinical examination can suspect an aneurysm which will be confirmed in next time with CT scan.

Case report:

We describe the case of a 67 years old male presenting to the emergency department for constipation and abdominal pain since few days. We found a hypertension in his medical history .He used tobacco .On examination: He was apyretic, his blood pressure was 170 /60, on the abdominal exam we find a pulsatile hypogastric mass. .All pulses are presents and we didn’t identify any abnormality. Biological tests are normal. Abdominal CT scan show a giant aneurysm of abdominal aorta. The patient was admitted in surgical department and was operated.

Conclusion:

Abdominal aortic aneurysm is diagnosed frequently after complications as rupture or dissection. Patients didn’t feel any disorders. It should be noted that the postoperative mortality rate is on average 4% to 5% for conventional surgery and 1% to 2% for end vascular treatment against 80% if the aneurysm is not in charge in time. Therefore, we should practice a good examination to don’t diagnose an abdominal aortic aneurysm.


Houda NASRI (CHARTRES), Rim HAMAMI, Olfa DJEBBI, Yosra GUETARI, Dkhera HAMDI, Saloua MANSOURI, Khaled LAMINE
08:30 - 17:40 #11218 - Contrast induced nephropathy after computer tomography of the pulmonary arteries in emergency settings.
Contrast induced nephropathy after computer tomography of the pulmonary arteries in emergency settings.

Introduction:

Contrast-induced nephropathy (CIN) is defined as iatrogenic deterioration of renal function following intravascular contrast media administration in the absence of another nephrotoxic event. CIN is one of the leading causes of hospital-acquired acute kidney injuries.

Contrast-enhanced computed tomography (CECT) of the pulmonary arteries is one of the most common imaging studies performed in the emergency department to evaluate patients with suspected pulmonary embolism (PE). The aim of this study was to define if CIN followed CTPA.

Methods:

We analyzed medical records of patients who received intravenous contrast for CECT in the emergency department (between January 2016 and April 2016). The outcomes measured were as follows: an increase in serum creatinine ≥ 44.2 mkmol/l or ≥ 25% 2 to 7 days after the contrast administration, severe renal failure with or without acute hemodialysis and renal failure as a contributing cause of death.

Results:

A total of 137 patients underwent CTPA, with acute PE in 46 patients (33,6 %) and 112 patient being hospitalized after CECT. We analyzed 90 hospitalized patient’s medical records and measured post procedural  serum creatinine level. Preliminary data shows that the incidence of CIN is 14.4 % (n=13 of 90), including 4 with acute PE. One patient (1.1 %) developed acute renal failure which required acute hemodialysis. 7 patient died and  the development of CIN was observed in 3 of deceased patients. CIN developed in 4 patients ( 9.3 %) with acute PE. Risks factors for CIN including age over 70, anemia, arterial hypertension, coronary artery disease associated with higher  CIN development; whereas other vascular diseases (peripheral, renal or cerebral), congestive heart failure, pre-existing renal disease, diabetes mellitus, the malignancy associated with CIN was not significant.

Discussion/conclusion:

The number of CIN incidences is high among emergency department population undergoing CTPA. CIN should be considered before emergency imaging requires intravenous contrast media in patients with suspected PE. Alternative investigation method must be applied when dealing with patients having pre-existing risk factors.


Anastasija FJODOROVA (Rīga, Latvia), Jevgēnijs KRAVČUKS, Anita KALĒJA, Oļegs SABEĻŅIKOVS
08:30 - 17:40 #11088 - Conversion disorder: symptom of a Subarachnoid Hemorrage.
Conversion disorder: symptom of a Subarachnoid Hemorrage.

Objetive:

Emphasize the importance of not considering the conversion disorder as the first diagnostic possibility in patients with neurological symptomatology.

Method:

A 67-year-old woman with no drug allergies who had a history of hypertension, dyslipidemia and hepatitis C virus. She was referred to the emergency by emergency ambulance because she suffered syncope with prodromes of nausea and headache with posterior vomiting and tongue bite. Diagnostic impression of emergency services at home was conversion disorder. In the emergency room she presents vomiting again, sphincter relaxation, headache and amnesia of what happened before. She refered headache for a few days and hypertensive crises.

Physical examination: Bad state, headache and weakness. Normal neurological examination. No meningeal signs. Normotensa Complementary tests: cranial CT with HSA (subarachnoid hemorrhage) of aneurysmal pattern with involvement of basal cisterns, midline grooves and both convexities A complete study with a CT angiography of Willis polygon was observed, with aneurysm in the anterior communicating artery Clinical trial: HSA secondary to rupture of anterior communicating artery aneurysm,Evolution: In observation unit she presents convulsive crisis and supraventricular tachycardia. Subsequently postcritical enters intensive care unit Arteriography and embolization of aneurysm were performed with complete occlusion without complications. After 24 evolves favorably and proceeds to leave the hospital.

Discussion: The most frequent cause of spontaneous SAH is the rupture of cerebral aneurysm. Aneurysmal subarachnoid hemorrhage (SAH) is a frequent and potentially curable disease, although morbidity and mortality, considered globally, is high. HSA is a medical emergency, its early diagnosis being essential (up to 20% are misdiagnosed initially) and admission for treatment of the patient in a suitable medium. The presence of HSA should always be suspected when there is an intense, abrupt onset headache, which may be followed by sensory disturbance, nausea, vomiting, neck stiffness and focal deficits including cranial nerve palsies. Symptoms of a Conversion Disorder can be motor problems such as coordination, weakness, paralysis, convulsions, fainting and sensory symptoms such as blindness, deafness, loss of touch and aphonia

CONCLUSION: Although the symptoms of a subarachnoid hemorrhage may be similar to those of a conversion disorder, it should be emphasized that the correct anamnesis with the information collected from the relatives and an exhaustive physical examination could have helped in this case to refer to the patient To the neurosurgical reference hospital and not to another for psychiatric assessment, thus delaying complementary tests, diagnosis and definitive treatment


Laura GOMEZ RODRÍGUEZ, Rocio RODRIGUEZ BARRIOS (MALAGA, Spain), Ana PEREZ TORNERO
08:30 - 17:40 #11284 - Cor triatrium: a congenital heart disease case report.
Cor triatrium: a congenital heart disease case report.

Introduction:

Cor triatrium is a rare congenital heart disease. Its frequency is less than 0.1% of clinically diagnosed heart disease and 0.4% of congenital malformations recognized at autopsy. The diagnosis is made mostly during childhood. Delayed diagnosis in the elderly is unusual.

It is due to the presence of a perforated fibro-muscular membrane dividing the atrium into two chambers: one proximal receives the pulmonary veins and the other distal containing the mitral valve. This heart disease is usually associated with other cardiac malformations and is complicated by atrial fibrillation (AF).

We report here the case of a cor triatrium in a 24-year-old male.

Case report:

A 24-year-old male without past medical history presented in emergency department for abdominal pain and vomiting. His vital signs were as follow: blood pressure of 75/45 mmHg, pulse rate of 64 beats/min, cold extremities, respiratory rate of 20 breaths/min, oxygen saturation with pulse oximetry as 92% on air room, heart and breath sounds were normal. The electrocardiogram showed atrial fibrillation at 64 beats/min and right bundle block. Chest X-ray showed cardiomegaly. The diagnosis of a hypovolemic shock secondary to acute gastroenteritis was made.

After administration of isotonic saline infusion (1000 ml) with norepinephrine use, the patient became hemodynamically stable.

A transthoracic echocardiogram was performed showing the presence of a membrane dividing the left atrium into two chambers, an important tricuspid regurgitation and pulmonary hypertension. The patient was transferred to a cardiac department for surgical excision of the membrane.

Conclusion:

Cor triatrium is a rare cardiac disease. The increased frequency of diagnosis in adults may be related to the technological improvement in echocardiography. The thromboembolic complications related to this pathology are to be feared.


Hanen GHAZALI (Ben Arous, Tunisia), Syrine KESKES, Aymen ZOUBLI, Anware YAHMADI, Mahbouba CHKIR, Ahlem AZOUZI, Sawsen CHIBOUB, Sami SOUISSI
08:30 - 17:40 #9853 - Correlation of Central Venous Pressure with Venous Blood Gas Analysis Parameters; a Diagnostic StudyAbstract Objective: This study was conducted to assess the correlation between central venous pressure (CVP) and venous blood gas (VBG) analysis parameters.
Correlation of Central Venous Pressure with Venous Blood Gas Analysis Parameters; a Diagnostic StudyAbstract Objective: This study was conducted to assess the correlation between central venous pressure (CVP) and venous blood gas (VBG) analysis parameters.

Abstract

Objective: This study was conducted to assess the correlation between central venous pressure (CVP) and venous blood gas (VBG) analysis parameters, to facilitate management of severe sepsis and septic shock in emergency department.

Methods: This diagnostic study was conducted from January 2014 until June 2015 in three major educational medical centers, Tehran, Iran. For patients selected with diagnosis of septic shock, peripheral blood sample was taken for testing the VBG parameters and the anion gap (AG) was calculated. All the mentioned parameters were measured again after infusion of 20 cc/kg normal saline 0.9% in 30 minutes.

Results: Totally, 93 patients with septic shock were enrolled, 63 male and 30 female. The mean age was 72.53±13.03 and the mean Shock Index (SI) before fluid therapy was 0.79±0.30. AG and pH showed significant reverse correlations with CVP, While HCO3 showed a significant straight correlation with CVP. These relations can be affected by the treatment modalities used in shock management such as fluid therapy, mechanical ventilation and vasopressor treatment.

Conclusion: It is likely that there is a significant statistical correlation between VBG parameters and AG with CVP, but further research is needed before implementation of the results of this study.


Alireza BARATLOO (Tehran, Islamic Republic of Iran), Alaleh ROOHIPOUR, Sahar MIRBAHA
08:30 - 17:40 #11304 - Correlation of CT Brain and GCS 15 with Head injury.
Correlation of CT Brain and GCS 15 with Head injury.

Background

Head injury is the most common presentation in patients with distracting mechanism of injury. Despite of high incidence and numerous studies performed there is much controversy about correct evaluation of these patients. The aim of this study was to find importance of brain Computed Tomography (CT) scans in patients presenting even with Glasgow Coma Scale (GCS) 15.

Materials and Methods

A prospective study of 101 patients was done with head injury with GCS 15 who were seen during a period of 2 years. The study population was selected by simple convenient sampling. Data collection tool was a questionnaire including GCS, H/O loc, seizure, vomiting, ENT bleed, Amnesia. Data was analyzed using chi square test, student t test and x2 test using SPSS software. <0.05 was considered to be significant.

Inclusion criteria-

1. GCS 15

              2. Any h/o loss of consciousness, seizure, vomiting, ENT bleed, amnesia

Exclusion criteria-

` 1. Time since injury >24hrs

2. Focal neurological deficit

Result

Statistically significant association was found between CT findings and GCS 15 with H/O Head injury. Head injury patients with GCS 15(t=6.55; p<0.001**) with CT findings (t=13.870; p<0.001**) is very significant.

Conclusion

Not all patients with minor head injury need brain CT scan. There is a significant correlation with the need of CT brain in patients with h/o head injury even if they present with GCS 15 with any h/o loss of consciousness, seizure, vomiting, ENT bleed,amnesia.


Dr Ketan PATEL (Ahmedabad, India), Anjali PATEL, Rignesh PATEL
08:30 - 17:40 #10510 - Critical Care in the emergency department: a descriptive study in a teaching hospital.
Critical Care in the emergency department: a descriptive study in a teaching hospital.

Background: Emergency department intensive care units have been increasingly used to improve patient care in a situation of shortage of "traditional" ICU beds. In developing countries it is not unusual for a critical care patient to stay for days in the emergency department. Some of these patients are not prioritized by traditional ICUs because of age, frailty or comorbidities.

Method: This prospective cohort evaluated 723 consecutive patients admitted to a 12-bed emergency department intensive care unit between September 2014 and February 2016. Age, SAPS 3 and surprise question (would you be surprised if this patient died in 1 year?) were recorded at admission. These patients were followed until death, transference or discharge.

Results:  A total of 723 patients were admitted during the period of the study. Median age was 61 and average SAPS 3 was 58. There were 97 patients older than 80 years. There were no serious comorbidities in 67,5% of the patients. The surprise question was positive in the other 32,5%. Life prolonging procedures were limited in 15,7% of patients. Mechanical ventilation was necessary in 38,5% of patients. 73,2% of these patients were transferred to other units, 13,1% died during intensive care, 8,5% were discherged home and 5,2% were transferred to other hospitals. Patients stayed in the unit in average for six days. None of the patients had written advanced directives.

Conclusion:  Patients admitted to our emergency department intensive care unit are complex patients with a long lenght of stay. Even though a significant percentage has serious life limiting ilness evaluated through surprise question, it was unusual to limit life-prolonging procedures and written advanced directives were completely absernt in our population.


Sabrina Correa Da Costa RIBEIRO (São Paulo, Brazil), Julio Cesar Garcia ALENCAR, Pedro Henrique Ribeiro BRANDES, Rodrigo Antônio BRANDÃO-NETO, Roger Daglius DIAS
08:30 - 17:40 #11690 - Crosstalk between mitochondrial fission and oxidative stress in paraquat-induced apoptosis in mouse alveolar type II cells.
Crosstalk between mitochondrial fission and oxidative stress in paraquat-induced apoptosis in mouse alveolar type II cells.

Paraquat (PQ), as a highly effective and nonselective herbicide, induces cell apoptosis through generation of superoxide anions which forms reactive oxygen species (ROS). Mitochondria, as regulators for cellular redox signaling, have been proved to play an important role in PQ-induced cell apoptosis. This study aimed to evaluate whether and how mitochondrial fission interacts with oxidative stress in PQ-induced apoptosis in mouse alveolar type II (AT-II) cells. Firstly, we demonstrated that PQ promoted apoptosis and release of cytochrome-c (Cyt-c). Furthermore, we showed that PQ broke down mitochondrial network, enhanced the expression of fission-related proteins, increased Drp1 mitochondrial translocation while decreased the expression of fusion-related proteins in AT-II cells. Besides, inhibiting mitochondrial fission using mdivi-1, a selective inhibitor of Drp1, markedly attenuated PQ-induced apoptosis, release of Cyt-c and the generation of ROS. These results indicate that mitochondrial fission involves in PQ-induced apoptosis. Further study demonstrated that antioxidant ascorbic acid inhibited Drp1 mitochondrial translocation, mitochondrial fission and attenuated PQ-induced apoptosis. Overall, our findings suggest that mitochondrial fission interplays with ROS in PQ-induced apoptosis in mouse AT-II cells and mitochondrial fission could serve as a potential therapeutic target in PQ poisoning.


Zhao GUANG-JU, Lu ZHONG-QIU (Wenzhou, China)
08:30 - 17:40 #11096 - CT head interpretation for suspected non-traumatic subarachnoid haemorrhage by emergency physicians; a retrospective diagnostic cohort study.
CT head interpretation for suspected non-traumatic subarachnoid haemorrhage by emergency physicians; a retrospective diagnostic cohort study.

Background

Given that a large proportion of patients with subarachnoid haemorrhage present outside of normal working hours, and that reports are often either by radiology trainees or not available until the next day, it is understandable that some emergency physicians may rely on their own interpretations of CT head scans to aid prompt disposition. Previous studies of CT head interpretation for trauma in the emergency department found that concordance with radiology reports varied dramatically. It is not clear whether emergency physicians can safely interpret CT head scans for patients presenting with non traumatic sudden onset headache. This study aims to address this by calculating the diagnostic accuracy of emergency physicians’ interpretations.

Methods

The study was performed at Addenbrookes Hospital emergency department in the UK. It was estimated that approximately 250 scans would be needed given that emergency physicians would likely only accept a sensitivity above 99%. Consecutive CT head scans performed for suspected subarachnoid haemorrhage, ordered from the emergency department, were identified through the radiology picture archiving and communication system. The notes were examined to ensure that all cases presented with non-traumatic headache and the primary treating physician suspected subarachnoid haemorrhage as the main or significant differential diagnosis. The subsequent exclusion criteria were then applied; age under 16, headache for more than 2 weeks, transfer from another hospital, previous brain surgery or known malignancy, previous aneurysm coiling, images or radiology report not available. All scans were performed on one of two 64 slice third generation multislice CT scanners with 5mm slices. The final neuroradiologist report was used as the gold standard. 22 emergency physicians took part with a 50:50 split between registrars and consultants. They were aware of the indication, and asked a dichotomous yes/no question as to whether they could see any significant abnormality on the imaging.

Results

260 scans met the inclusion criteria from January 2016 to December 2016. 19 scans were excluded. The average age was 46.5 and the average time from headache onset to scan was 2 days. The overall incidence of SAH was 7.9%, with a further 5 scans having other positive findings. The overall sensitivity of emergency physicians was 88.3% (62.6 - 95.3) and the specificity was 94.5% (90.6 - 97.1). Four scans were misinterpreted as negative - three cases of subarachnoid haemorrhage and one venous sinus thrombosis.

Discussion

Emergency physicians should not discharge patients based on their own interpretations of CT head imaging, although early neurosurgical referral for positive interpretations may be appropriate given the high specificity demonstrated in this study.


Dr Richard AUSTIN (Bedford, United Kingdom), Adrian BOYLE, Vazeer AHMED
08:30 - 17:40 #11418 - CT TRAUMA ANGIOGRAM: Are we making appropriate scanning decisions?
CT TRAUMA ANGIOGRAM: Are we making appropriate scanning decisions?

OBJECTIVES

This audit aims to determine if our current practice of liberal use of CT trauma angiogram is justified.

DESIGN AND METHODS

A retrospective analysis of 106 patients who underwent CT trauma angiogram (CT angiogram of thorax, abdomen and pelvis) from June 2015 to June 2016 was made. Patients selected were involved in trauma with trauma team activation, and these patients subsequently underwent CT trauma angiogram. The following trauma patients were excluded:

  • Paediatric patients that needed to be transferred to KKH (defined as less than 15 years old)
  • Abnormal CT brain or limb injuries that requires emergency surgical intervention or intensive care unit admission
  • Severely injured patient that requires intensive care unit or damage control surgery even without CT trauma angiogram

              Data were retrieved from trauma registry, emergency department and inpatient records.

RESULTS

106 patients had CT trauma angiogram as part of their trauma team workup. Their age ranged from 16 to 95 years old. 83 patients were male and 23 female. 83 patients suffered from road traffic accidents. From the 106 patients identified in this audit, 53 patient had a positive CT trauma angiogram as described. Among these group of patients, 6(11.3%) patients had hypotension, 19(36%) had tachycardia, 3(5.6%) had hypoxia, 16(30%) had a positive eFAST scan, 6(11.3%) had hyperlactatemia and 10(18%) patients required emergency blood transfusion. 36(64% compared to total sample) patients were Tier 1 trauma patients (Injury Severity Score >15), while 19(82%) underwent emergency surgical intervention such as damage control surgery or interventional radiology and 28(51%) of the patients required intensive care unit admission. No patient died within the positive CT finding group.

 

CONCLUSIONS

Patients who were hypotensive (SBP <90), hypoxic (<94% RA), had hyperlactatemia (>4.0),  a tachycardic (heart rate >100), a positive E Fast or required emergency blood transfusion will likely benefit for CT trauma angiogram. A significant proportion has a positive CT result (50%). A significant number of patients were Tier 1 trauma cases, while some need intensive care unit care and emergency surgical intervention. Hence we deem liberal CT trauma angiogram usage is justified within the context of a trauma team activation.

REFERENCES

1)      Uyeda JW1, Anderson SW, Sakai O, Soto JA.CT angiography in trauma. Radiol Clin North Am. 2010 Mar;48(2):423-38

2)      P Banerjee, R Soumen etc. CT Scans in Primary Survey for Polytrauma Patients. Advances in Computed Tomography Vol.2. 2013;2:46-51

3)      Low, R., Duber, C., Schweden, F. et al. Whole body spiral CT in primary diagnosis of patients with multiple trauma in emergency situations. Rofo. 1997;166:382–388.

4)      Leidner, B. Standardised whole-body computed tomography as a screening tool in blunt multitrauma patients. Emerg Radiol. 2001;8:20–28


Jasminah Begum KADER MYDIN, Sanjay PATEL (Singapore, Singapore)
08:30 - 17:40 #11661 - Dabigatran realted rectus sheath hematoma.
Dabigatran realted rectus sheath hematoma.

We report an unusual case of rectus sheath hematoma in a patient who was on dabigatran. Rectus sheath hematoma is sometimes difficult to diagnose and may cause life threatening shock. A 52 years old female with hypertension, diabetes mellitus and chronic atrial fibrillation presented to the department of emergency medicine of a tertiary care hospital with complaints of abdominal pain and swelling on left side of abdomen for one day. She had a history of renal transplant and was on dabigatran. She was having cough for the last few days and there was no history of trauma. On examination she was pale looking, hypotensive and tachycardiac. Her abdominal examination showed tender, ecchymotic swelling of 10 x 10 cm, extending from left hypochondrium to left iliac fossa. Her bed side ultrasound showed a large abdominal wall hematoma. Triple phase computerized tomography (CT) showed large left rectus sheath hematoma with contrast extravasation from inferior epigastric artery. Complete embolization of inferior epigastric artery was achieved with successful deployment of multiple coils. Patient was discharged after five days of uneventful stay in the hospital with gradual decrease of abdominal wall edema.


Qazi ZIA ULLAH, Qazi ZIA ULLAH (MUSCAT, Oman), Awatif AL ALAAWI, Mohammad Faisal KHILJI
08:30 - 17:40 #11157 - De winter st/t complex: an early sign of st segment elevation myocardial infarction.
De winter st/t complex: an early sign of st segment elevation myocardial infarction.

INTRODUCTION: Electrocardiogram (ECG) is usually the first and most important test in patients with acute coronary syndrome  which helps to diagnose as well as classify patients into ST elevation or non-ST elevation myocardial infarction (STEMI). Patients with STEMI require urgent reperfusion therapy. They may, however, sometimes present without obvious ST elevation in ECG resulting in delayed diagnosis and reperfusion therapy.

Identification of such STEMI equivalents, therefore, becomes very important for physicians as well as interventional cardiologists.

CASE REPORT: A 69 year-old-male presented to the emergency department (ED) with retrosternal pain radiating to left arm occurred 1 hour before ED admission. He was hypertensive with a history of non-ST elevation myocardial infarction one month later. He was hemodynamically stable with a blood pressure of 130/60 mmHg and a regular pulse rate of 80 beats/min, respiratory rate was 22 breaths per minute and the oxygen saturation was 97% on air room.

The admission ECG showed a 2 mm upsloping ST segment depression at the J point which continued into tall, positive T‑waves in inferior and basal leads. There was ST-segment depression of 3 mm with negative T waves in anterior leads. The diagnosis of De winter complex, a STEMI equivalent, was made. Anti-thrombotic medications were administrated. Ten minutes after his admission in the ED, he developed a sudden cardiac arrest with a ventricular fibrillation recovered after one electric chock. The patient became hemodynamically stable. An ECG performed showed an ST segment elevation of 2.5 mm in inferior and basal leads with a specular reflection in anterior precordial leads confirming an obvious STEMI diagnosis. A pharmacological reperfusion treatment was immediately performed. Coronary angiography showed a tight thrombotic stenosis of the right‑coronary artery. An intracoronary stent was implanted and final injection showed a thrombolysis in myocardial infarction grade 3 flow.

CONCLUSION:

De winter ST-T syndrome on ECG is an early specific STEMI equivalent. Identifying this sign is primordial for the emergency physician and should alert him to undertake an immediate adequate treatment.


Hanen GHAZALI (Ben Arous, Tunisia), Ihsen HNEN, Hedia GNENA, Ines CHERMITI, Najla ELHENI, Ahlem AZOUZI, Mohamed MGUIDICH, Sami SOUISSI
08:30 - 17:40 #11780 - Dear SIRS, you can be SWEET but I hate you! A sweet syndrome mimicking severe sepsis.
Dear SIRS, you can be SWEET but I hate you! A sweet syndrome mimicking severe sepsis.

Introduction :
Skin disorders are common in emergency department especially when associated with fever. Twenty five to forty percent are related to a decompensation of a preexisting skin disease. In 1964, Sweet describes a “strange eruption” which is immunologically mediated and since that date the dermatitis bears his name. In the emergency department, the diagnosis of this pathology may be difficult especially when the presentation is severe or associated with fever since it face the physician to a therapeutic dilemma: giving antibiotics or steroids.

Case presentation :

A 43 years old man with no past medical history was transported to the emergency department by the mobile emergency service with a chief complaint of weakness and fever associated with a disseminated skin eruption. He was conscious but very weak and he has fever about 38.5°C. Systolic blood pressure/Diastolic blood pressure was about 90/60 mmHg and heart rate about 96 per minute. Initially he was managed as severe septic syndrome since we found nitrites in urine sample associated with SIRS. A PCT was performed and the amount was less than 0.5 ng/ml so we performed a skin biopsy which showed a neutrophilic infiltration consistent with Sweet syndrom. The patient was given steroids and had rapid improvement of his complaints.

Conclusion :
Sweet syndrome is a possible diagnostic in patient with skin eruption and non infectious SIRS in the emergency department


Mohamed Amine KALLEL (tunis, Tunisia), Zaouche KHEDIJA, Maghraoui HAMIDA, Mohammed Chekib BOUALI, Majed KAMEL
08:30 - 17:40 #9926 - Decompressive craniectomy in a patient with severe traumatic brain injury during mild therapeutic hypothermia.
Decompressive craniectomy in a patient with severe traumatic brain injury during mild therapeutic hypothermia.

Background:

Mild therapeutic hypothermia (MTH) and decompressive craniectomy are therapeutic measures used for the treatment of intracranial hypertension (ICHT) refractory to medical treatment and cerebrospinal fluid drainage. In patients with traumatic brain injury, MTH can reduce intracranial hypertension, altough its benefit on functional outcome remains unclear. Emergency craniectomy is the last stage in the management of increased ICHT, but there is no agreement on the best time and indications of this surgery. Until now, there is great controversy in using both treatments concomitantly due to the alterations in coagulation during MTH.

Case Report

A 31-year-old patient with severe traumatic brain injury was admited to our Emergency Department. 2 days after ICU admission the patient developed ICHT refractory to medical treatment. Hence, MTH was initiated by a non-invasive system at 34 degrees. After a transient improvement, the patient presented ICHT again, having to perform a decompressive craniectomy to control it, keeping the patient in mild hypothermia. Standard coagulation tests were normal. During the intraoperative period, rotational thromboelastography was performed in which no alterations were observed. Surgery took place with neither significant bleeding nor hemodynamic imbalances. On day 9, gradual rewarming was obtained reaching 36 degrees. After weaning, the patient responded to simple verbal commands, with spontaneous eye-opening. He had a favorable evolution with a good overall functional capacity at discharge.

Discussion:

One of the major complications of hypothermia is impaired haemostasis. Several trials did not show any additional bleeding in the hypothermia group.

In our case, there was no increased bleeding intra or postoperatively. The performance of neurosurgical interventions in patients with severe traumatic brain injury in previous treatment with moderate hypothermia should no imply withdrawal of hypothermia during the intraoperative period. More studies are needed to establish the safety and efficacy of both treatments.


Ángel CABALLERO (Barcelona, Spain), Adriana JACAS, Marta MAGALDI, Andrea CALVO, Jaume FONTANALS
08:30 - 17:40 #11086 - Delay in alteplase administration in acute ischemic stroke patients.
Delay in alteplase administration in acute ischemic stroke patients.

BACKGROUND. Thrombolysis intravenous treatment with alteplase (intravenous recombinant tissue-type plasminogen activator, IV tPA) is the first line treatment and is associated with improved outcome in acute ischemic stroke. Several factors have been shown to be outcome predictors after thrombolysis. Although the beneficial effect of IV tPA decreases progressively over time, in long-term outcome. There is no many studies demonstrating the early clinical effects in the early clinical outcome relatad with the OTT.

MATERIAL Y METODS. An observational and prospective study was performed in Hospital Universitario Virgen de la Victoria Málaga, during 2013 and 2016. Inclusion criteria was patients with acute ischemic  stroke treated with alteplase. Exclusion criteria were those who underwent endovascular treatment and those with initial modified Rankin Scale (mRS) ≥3, final diagnose were differente than ischemic stroke or timelines of treatment were unclear. Finally, 120 consecutive patients evaluated and treated according to the criteria of the European Summary of Product Characteristics for tPA treatment until 4.5 hours were included in the analysis.

Stroke severity at baseline and 24 hours ontset was assessed with the NIHSS scale. Patients were categorized according to the clinical outcome into 3 groups: poor imporvement, when the NIHSS-difference between NIHSS baseline and NIHSS 24hours score was ≤5 (n=56); moderate improvement when score was from 6 to 10 (n=39); and good improvement when the score was ≥10 (n=25). All the clinical assessment were calculated by Neurologist. OTT was calculated since the time of first stroke symptoms (or last known normal time) room until the alteplase bolus.

RESULTADOS. 48 females. 66,5 ± 11,3 years old. Cardiovascular risk factors:  74 patients with arterial hypertensión (61,7%), Dyslipemia (43,3%), Mellitus Diabetes (30,8%) and smokers (22,5%). 45 pacientes (37.5%) had an cardioembolic stroke at final diagnosed. OTT mean 150 ± 41,8 minutes. Baseline NIHSS score 15,4 ± 5, 24h NIHSS score 9,2 ± 6,9. Primary intracerebral haemorrhage type 2 3,3%. The mean OTT in each clinical outcome: Poor improvement 163 ± 45 minutes; moderate improvement  142 ± 26 minutes and optimal improvement 133± 46 minutes (p=0,012). Correlation between OTT and NIHSS difference 24 h R Pearson = -0,365(p < 0,001). The point cloud representation between both factores were calculated.  Next, Simple lineal regression of point cloud was “(NIHSS differences 24h)= 12,798 – [0,044 *=OTT (min)]”, so each 22,7 minutes of delay in OTT the patient is going to lose 1 NIHSS score point.  

CONCLUSIONS. Early Clínical improvement depends on the onset-to treatment in acute isquemic stroke treated with alteplase. The delay in administration could condition the good improvement. Trombolitic treatment should be administer as soon as possible. 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Natalia GARCÍA-CASARES, Carlos DE LA CRUZ COSME, Francisco TEMBOURY RUIZ, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11753 - Delayed hyperbaric treatment for delayed neurologic sequelae of carbon monoxide poisoning: two cases.
Delayed hyperbaric treatment for delayed neurologic sequelae of carbon monoxide poisoning: two cases.

Objective: Delayed neurologic sequelae (DNS) may occur after severe carbon monoxide (CO) poisoning. The toxic mechanisms underlying DNS are still unknown even if various “extra-hemoglobin” effects (mainly involving inflammatory and oxidative pathways) are suggested. Treatment of DNS is not standardized and yet debated. We describe two cases of DNS successfully treated with late and repeated hyperbaric oxygen therapy (HBOT) associated with anti-inflammatory and antioxidant therapy. Case 1: 49 years-old woman was found confused and dysphoric, early in the morning, in the bedroom. The husband was see dead near her; in the room there was a wheelbarrow filled with coals. At admission, the patient was drowsy, with HbCO 6.8% and abnormal glycemia, myoglobin, plasma B-type natriuretic peptide and troponins. The patient was treated with normobaric oxygen for few hours and discharged the day after, without specific indications/follow-up. One month later the patient presented disorientation, ataxia, apraxia, amnestic aphasia, catatonia. EEG revealed severe diffuses slowing alternated by diffuse slow theta-delta waves bouffées. Brain-MRI revealed diffuse signal hyperdensity in subcortical white matter, especially at bilateral semiovals centres. After 21 HBOT sessions (in 3 weeks) all neurological symptoms resolved except for minimal hands postural tremors. Brain-MRI and perfusional-SPECT (6-months later), confirmed previous alterations. Case 2: 34 years-old woman found unconscious at home. At ED she was awake and presented with psychomotor retardation, tachycardia, and multiple lung consolidations. HbCO was 20.4%, serum creatinine and cardiac troponin levels were elevated. She underwent endotracheal intubation and 2 sessions of HBOT. EEG revealed severe diffuses lowing with sharp and triphasic elements. Brain MRI showed no abnormalities. After 25 days, she was transferred to a rehabilitation hospital: at that time, she was awake, quite oriented with mild psychomotor retardation. In the following two weeks she improved, then she developed neuropsychological and severe neurological deterioration. Brain-MRI revealed new diffuse white matter T2 hyperintensities. Patient was treated with 39 HBOT sessions concomitant to administration of corticosteroids and acetylcysteine. Her neurological signs as well as brain MRI abnormalities, progressively improved. She was discharged at a day clinic 159 days after CO-exposure. Conclusion: These cases highlight that clinicians should monitor for DNS and that CO poisoning pathology is a markedly complex mechanism that involves extensive disruption of cell signaling and profound oxidative stress. In our experience multiple HBOT sessions concomitant with interventions that target some CO’s “extra-hemoglobin” effects could be crucial for the recovery of these patients, together with anti-inflammatory and antioxidant therapy.


Sarah VECCHIO, Davide LONATI (PAVIA, Italy), Lorenzo CELLI, Fiammetta LOGI, Francesco TOMAIUOLO, Giuliano VEZZANI, Carlo Alessandro LOCATELLI
08:30 - 17:40 #11099 - Delayed Onset of Cardiomyopathy Induced by Glufosinate Intoxication : A Case Report.
Delayed Onset of Cardiomyopathy Induced by Glufosinate Intoxication : A Case Report.

Basta™ (Bayer, Germany) is one of the most widely used herbicide in many countries. Basta™ contains glufosinate ammonium (18.5%) and surfactant (30%) of sodium polyoxyethylene alkylether sulfate (AES). AES as surfactant has been considered to play a major role in cardiovascular collapse. The cardiovascular effects of AES are known to be the principal cause of death. Unlike the previous studies that reported the cardiovascular effects with AES intoxication, we present a case with delayed onset of cardiomyopathy induced by Basta™.

A 78-year old female visited the emergency room with a history of glufosinate ammonium ingestion. She ingested 400 cc of Basta™ 10 hours before the admission to our clinic for the purpose of suicide. She had visited other emergency room 10 minutes after ingestion of Basta™ and underwent gastric lavage. She was alert at the time of visiting the previous clinic, and became semicomatous at the time of intubation. Her vital signs were as follows: blood pressure 100/50 mmHg, pulse rate 112 per minute, respiratory rate 22 per minute, and body temperature 36.4℃. Initial laboratory results were as follows: pH 7.167, pCO2 73.4 mmHg, pO2 126.1 mmHg, HCO3 19.7, base deficit 12.2, FiO2 1.0, lactic acid 4.96 mmol/L, ammonia 131 μ㏖/L, creatine kinase (CK) 132 U/L, creatine kinase myocardial bound (CK-MB) 1.4 ㎍/L, and hs-troponin I (TnI) 0.027 ng/㎖. To treat persistent metabolic acidosis, continuous renal replacement therapy (CRRT) as continuous venovenous hemodiafiltration was done on the day of admission. At two hours after admission, blood pressure was 90/52 mmHg and found appropriate to start norepinephrine infusion. Initial electrocardiography (ECG) showed sinus tachycardia with T wave inversions in lead Ⅱ, Ⅲ, aVF, which was changed to normal sinus rhythm on the fourth day of admission. On the second day of admission, echocardiography for the evaluation of hypotension showed no regional wall motion abnormalities (RWMAs) and ejection fraction (EF) was observed as 60%. Cardiac enzymes levels were as follows: CK 63 U/L, CK-MB 2.6 ㎍/L, and TnI 0.067 ng/㎖. On the fourth day of admission, mental status was alert and CRRT was stopped. On the thirteenth day of admission, ECG showed sustained ventricular tachycardia twice without any changes in vital signs. On eighteenth day of admission, decrease in blood pressure was noted and TnI was elevated to 0.713 ng/㎖. Echocardiography showed RWMAs on mid segment of left ventricle, which was suitable for stress-induced cardiomyopathy (SIC). EF was preserved as 50%. Based on RWMAs, cardiologist did not consider presence of any coronary artery disease; hence evaluation of coronary artery was not performed. On twenty-third day of admission, she was discharged to the primary care clinic; however there was no improvement in RWMAs in the repeated echocardiography. On the thirty-ninth day of admission, she exhibited no symptoms and the repeated echocardiography showed no RWMAs and EF was improved to 62%.

In Basta™ intoxication, cardiovascular collapse is the principal cause of death. AES as a surfactant has been considered to play a major role in cardiovascular collapse. AES is known to induce vasodilation and negative inotropic and chronotropic responses. The vasodilatory effects induce hypotension by the increased production of nitric oxide (NO) via endothelium-dependent and endothelium-independent mechanism. Moreover, AES exhibited negative chronotropic effects on atrium in a concentration–dependent manner in in-vitro study. Combined effects on vasodilation and negative inotropic response produce hypotension from AES and Basta™ intoxication. In this case, SIC was reported as one of the presentation of glufosinate intoxication at eighteen days after Basta™ ingestion. The sympathetic nerve activation produced by the reaction to hypotension after Basta™ ingestion might be one of the causes of SCI. However, there exists no explanation on delayed onset of SCI after stabilization of blood pressure. The latency period of eighteen days was not usual in Basta™ intoxication. The difference from the previous cases is the composition of Basta™ sold in South Korea. The toxic effect of Basta™ containing polyxyethylene lauryl ether and sodium lauryl sulfate has not been reported yet. The vasodilatory effect of polyxyethylene lauryl ether via increased NO generation and calcium has been reported. It is hypothesized that the difference in composition might have an effect on the latency in Basta™ intoxication and more studies on Basta™ with the surfactant other than AES are necessitated. In cases of glufosinate intoxication with the surfactant other than AES, delayed onset of SIC should be considered as one of the causes of cardiovascular event.


Eun Jung PARK, Eun Jung PARK (Suwon, Republic of Korea), Younggi MIN, Minjeong LEE
08:30 - 17:40 #11080 - Dermatologic lesion of clinical diagnosis in Emergency Department.
Dermatologic lesion of clinical diagnosis in Emergency Department.

CASE REPORT: 36-year-old farmer with no known medical or surgical antecedents. She comes to the Emergency Department for the appearance of a blistering lesion on the fourth finger of his right hand. Despite having started antibiotic treatment with cloxacillin, the lesion had progressed without improvement. The patient does not report fever or generalized symptoms, and on examination she has a blistering lesion on an erythematous base on the finger (Figure 1). No lymphadenopathy is present.

DIFFERENTIAL DIAGNOSIS: Burn, erythema multiforme, pyodermatitis, anthrax, cutaneous tuberculosis, Orf nodule, malignant tumor lesion, tularemia

EVOLUTION: An x-ray is performed showing no bone involvement (Figure 2) and the lesion is sampled for culture that discards bacterial infection. The lesion is compatible with an Orf nodule and the clinical history is determinant to reach this diagnosis since the patient recognizes habitual contact in her work with lambs, sheep, cows and pigs. The histological study finally confirmed the diagnosis.

FINAL DIAGNOSIS: Orf nodule

DISCUSSION: the Orf nodule or milkers' node is an uncommon zoonosis caused by a parapoxvirus, which infects sheep, goats, and cows. It is an occupational dermatosis, whose transmission to humans is produced by direct contact with infected animals or contaminated materials.

The diagnosis is established with the presence of the characteristic cutaneous lesion, the compatible histology and the epidemiological antecedent of contact with infected animals. The isolated pathological anatomy is not pathognomonic, although typical acanthosis and vacuolization of epidermal cells, and infiltration of plasma cells, macrophages, histiocytes, lymphocytes, and cytoplasmic viral inclusions.

The incubation period is 3 to 7 days. Clinically the lesion passes through different stages of evolution: initial maculo-papular lesion during the first week, followed by a dianiform morphology that lasts one or two weeks, to later acquire a nodular, papillomatous form, and finally a crusty lesion that disappears.

It does not need specific treatment since it resolves spontaneously, although complications can appear especially in immunosuppressed, as bacterial superinfection, the eritema multiforme or the dissemination of the lesions.


María Del Carmen LAHOZA PÉREZ (ZARAGOZA, Spain), Daniel SÁENZ ABAD, Jordi PONS DOLSET, Ana ILUNDAIN GONZÁLEZ, Ana AGUDO TABUENCA, Sofía LUNA GARCÍA
08:30 - 17:40 #10888 - Descriptive study on the transfer of patients in emergencies. We can improve?.
Descriptive study on the transfer of patients in emergencies. We can improve?.

 OBJECTIVE

To quantify the number of transfers carried out in an emergency service by emergency medical equipment, medical-medical and any reports that correspond to the information transmitted verbally.

METHODOLOGY.

Medical-doctor transfers between the dates of October 1, 2016 and December 1, 2016 are collected in a third-level hospital emergency department, recording the same in the patient's electronic medical record by means of the professional's note Receives the transfer. The information described above is compared with those that have been written in the report of the outpatient emergency doctor afterwards and the degree of agreement of the same is analyzed. It is considered concordant if at least 3 of the 4 items described below indicate the same information.

  1. Reason for activation of the outpatient emergency department.
  2. Clinical judgment or suspected diagnosis.
  3. Treatment administered during assistance or transfer.
  4. Severity of disease or injury to the patient. (Triage).


RESULTS.

  • Transfers recorded in medical records: 134.
  • Matching transfers: 75
  • Transfers not done or done to triage nursing: 14
  • Non-matching transfers: 45


CONCLUSIONS.

In the majority of the patients transferred to our emergency department by the outpatient emergency teams, a good transfer is made between the doctor who moves and the patient. With the new emergency triage system (SET), the outpatient emergency doctor sometimes transmits medical information to nurses. We can still improve as there is around 33% of transfers in which it can be said that communication between professionals has not been adequate.


Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO, David NUÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #10896 - Detection of Child maltreatment: signs and symptoms in children / Detection of Child maltreatment based on parental characteristics (Childcheck)/Implementation with the help of mandated training and e-learning/ Detection of Elderly abuse.
Detection of Child maltreatment: signs and symptoms in children / Detection of Child maltreatment based on parental characteristics (Childcheck)/Implementation with the help of mandated training and e-learning/ Detection of Elderly abuse.

Dear Madam, Sir

 

Here you will find a proposal for a Family Maltreatment Track for the EuSEM 2017. We would like to present four different subjects by four different presenters. Each speciallized in the subject they would present. The opportunity to organize this track was offered to us last year in Vienna. This offer was made by the formar president Dr. Barbara Hogan. We have also been in contact with Mr. Michel de Bisschop. We hope you will agree with our proposal and give us the opportunity to present these important and successfull researches. Below you will find one abstract, the other three you will find in the attachment.

 

 

Detection of Family Maltreatment at the Emergency Department

The emergency department (ED) is the main system for crises based health care visits. It is estimated that 0.2% -10% of ED visits concern child abuse.  Screening tools, increasing awareness by training with learning , recognizing parental risk factors and abuse in the elderly at the ED are discussed in this symposium.

Title Detection of Child maltreatment: screening at the emergency departments.

Systematic  screening  can improve the detection rate of suspected child abuse . Important  questions  for optimal implementation  are :

  1. What is the validity of the (ESCAPE) screening tool?  This instrument included  the items : consistent history, delay in seeking medical help, injury fits with developmental level,  interaction, top-toe exam, doubt about safety). The validity was evaluated in the Netherlands in 18,275 children and the predictive value for suspected child abuse  was high (sensitivity 0.80 and specificity 0.98).
  2. The screening instrument need also to focus on emotional abuse
  3. Are suspicion of child abuse as detected by screening at the ED justified? 10% of the positive screened children were referred to the hospital /local child abuse team for further evaluation. The number needed to screen to detect one case of child abuse is 850.
  4. Training of ED nurses and making screening mandatory  increased the screening rate from 20% to 67%. The detection rate for suspected abuse was 5 times higher for screened compared to non -screened children.

Systematic screening for child abuse in emergency departments is effective.  The ESCAPE instrument and ED staff training are recommended to improve screening and the detection rate of child abuse.

 

Prof Dr Henriette A Moll, paediatrician

Department of paediatrics, ErasmusMC –Sophia Childrens Hospital

 

 

 

 [AS-A1]50 van de 78 nu lidmaatschap


Henriette MOLL, Hester DIDERICH (THE HAGUE, The Netherlands), Marielle DEKKER, Sivera BERBEN
08:30 - 17:40 #11111 - Developing tools to improve the outcome for patients presenting with sepsis to a regional hospital in Australia.
Developing tools to improve the outcome for patients presenting with sepsis to a regional hospital in Australia.

Developing tools to improve the outcome for patients presenting with sepsis to a regional hospital in Australia

 

 

Upon the release of the Sepsis 3 guidelines we were concerned that there was no clear system in place for patients presenting with likely sepsis to the Emergency Department at South West Healthcare. We identified that there was a general lack of awareness amongst many staff members, both medical and nursing, regarding time critical interventions known to improve survival rates and reduce morbidity in patients with sepsis. We had no protocols or guidelines in place to either recognize patients with sepsis or to facilitate standardized treatment to those patients.

 

In order to assist us to redress this situation, we successfully applied for a funded project with the Emergency Care Clinical Network (ECCN), to improve the identification and management of sepsis in our emergency department. 

 

As a result of the project we developed a risk assessment screening tool to be used at triage and a sepsis management pathway to be used for those patients identified as being at risk for sepsis. These tools were developed by a group of practitioners from both nursing and medical disciplines; staff were provided with a variety of educational opportunities to launch the routine use in our department.  We also held a Sepsis awareness education day that was open to practitioners in neighbouring community health services.

 

The benefit of this project has been improved staff knowledge of evidence based management and improved management of patients presenting with sepsis. We have audited the outcomes of patients presenting both before and after the implementation of our risk assessment and management pathway tools and preliminary data has indicated a reduction in the mortality rate.

 

 


Susan THOMAS, Susan THOMAS (Warrnambool, Australia)
08:30 - 17:40 #11651 - Development & effect of a multi-modality disaster training program for emergency nurses.
Development & effect of a multi-modality disaster training program for emergency nurses.

Objective: To develop a multi-modality disaster training program for emergency nurses and to investigate the effect of the program.

Background: Despite the importance and perception of emergency nurses in disaster crisis, a standardized program to develop competencies are still lacking in Korea. None exist that focus on emergency nurses that are left in the hospital to care for victims transported from the scene. Since disaster response requires multiple aspects of competencies, it is important to develop a multi-modality training program that is best suitable for the content to be trained.

Methods: The curriculum was developed using Kern’s 6-step approach. Downing’s construct validation was used to validate the program. Contents were developed after reviewing all the related evidence references. Educational environment, methods, instructor, and assessor were standardized. All assessment checklists were validated using content validity index. And consequences were validated using pre- and post-intervention differences. The educational intervention developed is called the TIPSS Course: Triage, Incident Command, Procedures (Life-Saving), Surge Capacity, and Special Hazards. It consisted of a 3-day workshop for selected 30 emergency nurses. The course consisted of lecture, followed by technical skills training, triage exercises, and ending with crisis management and problem-solving. Triage exercises were done using virtual and table-top simulation. The hands-on skill consisted of airway management, needle decompression, intraosseous infusion, contaminated wound care, and splinting techniques. Crisis management, focusing on incident command set up and managing surge capacity were trained with table-top simulation. And problem-solving training was done with scenario-based mannequin simulation. The scenario consisted of radiation exposed patients from a major earthquake event. Disaster Preparedness Questionnaire for Emergency Nurses (DPQ-EN), which was derived from the International Council of Nurses Framework of Disaster Nursing Competencies, was used to assess the perception changes of the participants. All pre-to-post differences within subjects were analyzed with paired t tests. The statistical level of significance was set at 0.05.

Results: Content validity index were 0.92. All the categories of the DPQ-EN survey, consisting of basic concepts, planning, patient care, psychological issues, special hazards, epidemiology, communication, personal preparedness, and ethics improved post-training. Patient care and special hazards improved the most. The participants were assessed on disaster nursing technical skills, accuracy of triaging, and crisis and problem-solving competencies using validated performance checklists. The differences were all statistically significant (p<0.05).

Conclusion: A multi-modality disaster training program for emergency nurses positively affected perception and performances of the participants.


Jiyoung NOH (Seoul, Republic of Korea), Hyun Soo CHUNG
08:30 - 17:40 #10125 - Diabetic keto-acidosis in association with Boerhaave syndrome.
Diabetic keto-acidosis in association with Boerhaave syndrome.

We present this case of a 23-year-old male with Type 1 Diabetes Mellitus presenting to the Emergency Department in the early morning with reduced level of consciousness, vomiting, ketonuria, and acidemia.  He had been brought to the Emergency department by land ambulance.  It was quickly established that the patient was in Diabetic Ketoacidosis (DKA) with a pH of 6.7, glucose initially unrecordably high at >60mmol/L and blood ketones >3mmol/L.  Management of the DKA was commenced in the E.D. with fluid resuscitation and a fixed rate insulin infusion (0.1 units/kg/hr).  Initially the presumed precipitant cause for the DKA was thought to be gastroenteritis as there had been no collateral history available at the time of initial presentation.  Electrocardiograph showed Atrial Fibrillation with Fast Ventricular Response.  No cause was identified for this.

 

When the patient’s Father arrived in the E.D. he expressed concern that he thought that his son may have been assaulted.  He had based this assertion on his son having an unusually swollen face and neck.  A friend who lived with the patient gave further history.  Explaining that the patient had been unwell for the previous one day with abdominal pain, retching and vomiting.  In particular, the patient had been forcefully retching out of a car window whilst a passenger returning from a party, where he had been DJ-ing that evening.  He was found unresponsive with Kussmaul breathing a few hours later.  The friend confirmed there was no history of assault, drug or alcohol use.

 

Further examination of the patient revealed extensive subcutaneous emphysema to the patient's neck and face.  Chest radiograph showed a pneumomediastinum and extensive subcutaneous emphysema to the soft tissues of the upper thorax and neck.  A diagnosis of spontaneous oesophageal rupture (Boerhaave syndrome) was made.

 

The patient was treated with intravenous antibiotics and received Surgical, Medical and Critical Care input whilst in the Emergency Department.  Once stabilised he was transferred to the Critical Care Unit.  Computerised tomography of the thorax and abdomen performed later in the day showed a thickened distal oesophagus with inflammatory fat stranding, the oesophageal perforation having spontaneously resolved.  The patient made a good recovery with 24-hour treatment on a fixed rate insulin infusion.

 

This case is interesting as it represents a rare case of spontaneous oesophageal perforation (Boerhaave syndrome) in association with a Diabetic Ketoacidosis.  The authors were alerted to the presence of the condition by parental concern on the part of the change of the patient’s appearance as well as by physical findings of subcutaneous emphysema.  The potential for spontaneous oesophageal perforation should be considered in cases of Diabetic Ketoacidosis where there has been a history of vomiting and retching.  Additionally, oesophageal perforation can also be a cause of atrial fibrillation as was seen in this case.


Dr Jonathan HOLMAN (Cardiff, ), Mayada ELSHEIKH, Stephen BUSH
08:30 - 17:40 #10675 - Diagnosis of diaphragmatic hernia after episode dyspnea.
Diagnosis of diaphragmatic hernia after episode dyspnea.

Medical History:

No known drug allergies.

Personal medical history of hypertension and myasthenia gravis

80 year old woman presenting episode of acute onset dyspnea from 2 days accompanied by gastroesophageal reflux while traveling by car according refers ago. Afebril.No abdominal pain and alteration in urination or intestinal.No habit of chest pain.

Browse: Conscious, oriented and cooperative, good, well hydrated and perfused condition, eupneic

Rhythm and regulate cardiac auscultation, no pathological sounds auscultation

Respiratory auscultation with vesicular murmur preserved; rhonchi and scattered expiratory wheezing in both lung fields

Complementary tests:

Radiography of toórax: diaphragmatic hernia is large evidence

Blood test: Leuc: 5910 U / dl (Neutrophils: 82.9% Lymphocytes: 9.9%), creatinine 0.3 mg / dl, Urea 47 mg / dl, normal ions, C-Reactive Protein: 8.2 mg / l,

Evolution and treatment:

For the radiographic finding is discussed with general surgeon on call who decides Metoclopramide therapy, aerosol therapy for treatment of dyspnea and complete analytical study.

After further testing and symptomatic improvement in the patient is consensual by the surgeon on duty proceeding to home discharge. It quotes the patient's preferred approach esophagogastric surgery consultation.


Rafael INFANTES RAMOS (Málaga, Spain), Carolina GARRIDO CANNING, Jose Ignacio VALERO ROLDAN, Maria Victoria ALARCON MORALES, Cristina FERNANDEZ- FIGARES MONTES, Maria Eugenia REYES GARCIA
08:30 - 17:40 #10674 - Diagnosis of gastric cancer after upper gastrointestinal bleeding.
Diagnosis of gastric cancer after upper gastrointestinal bleeding.

Present Complaint

Patient, 58 years old with no drug allergies. He denies toxichabits .

Personal medical History: permanent Auricular Fibrilation , hypertension with hypertensive heart disease , dyslipidemia , GERD with a history of peptic ulcer operated at 18 years old, remaining asymptomatic to date.

Treatment: Sintrom , Digoxin , Omeprazole, Irbesartan , Atorvastatin .

Surgical procedures: pepticulcer , dorsal lipoma.

Patient came to emergency service feeling dizzy with unsteady walking , effort dyspnea , epigastric pain and melena stools features diagnosing ananemic sd. and proceeding to transfusion of one unit of erythrocytes.

He was given a preferred appointment for review by Digestive specialist..

After 15 days he goes back to the emergency service with persistence of symptoms vomiting increased (similar in characteristics to previous ones).

He has not been cited by Digestive yet and he denies taking pain killers.

Exploration:

Arterial Tension 96/45mmHg , Heart Rating 57 bpm, Sat02 97% , Tª 36.3 ° C, Normal hydrated , skin and conjunctival pallor.

Cardiorespiratory auscultation : arrhythmic without blowing or audible fret, vesicular murmur preserved .

Abdominal: Globular , soft and depressible abdomen, hepatomegaly or splenomegaly was not palpable , painless, no signs of peritonism. DRE remains of melena .

Lowerlimbs: no edema or signs of deep vens Thrombosys or phlebitis .

No neurological deficitis evident .

Complementary Test

Blood test : Hb 8.3 g / dl Ht 26.1% MCV 81.5 MCH 22.1 pg, Platelets : 185000 leukocytes 8978 ( neutrophils 78,6 %, lymphocytes: 17,3 %) TP 24.2 sec, INR:1,76, Urea: 51; Creatinine: 0.38, Glucose: 107, K: 4.34, Na: 137

Evolution

Nasogastrictuve is placed draining content clear appearance . Proceed to an urgent gastroscopy where a partial gastrectomy with gastroenterostomy Billroth I is objetived.Upper gastrointestinal bleeding secondary to probable neoplasia in gastric side of the anastomosis. Biopsy of the lesion is taken .

Currently the patient is admitted by Digestive study to complete


Rafael INFANTES RAMOS (Málaga, Spain), Jose Ignacio VALERO ROLDAN, Carolina GARRIDO CANNING, Cristina FERNANDEZ- FIGARES MONTES, Maria Eugenia REYES GARCIA, Ivan VILLAR MENA
08:30 - 17:40 #11321 - Diagnostic accuracy of focus cardiac and venous ultrasound in patients with shock and suspected pulmonary embolism.
Diagnostic accuracy of focus cardiac and venous ultrasound in patients with shock and suspected pulmonary embolism.

Objective: Evaluate the diagnostic performance of focus cardiac ultrasound (US) alone and combination with venous US in patients with shock and suspected pulmonary embolism (PE).

Design and setting: Consecutive adult patients with shock and suspected PE, presenting to two Italian Emergency Departments, were included. Patients underwent cardiac and venous US at presentation with the aim of detecting right ventricular (RV) dilation and proximal DVT. Final diagnosis of PE was based on a second level diagnostic test or autopsy. 

Results: Among the 105 patients included in the study, 43 (40.9%) had a final diagnosis of PE. Forty-seven (44.8%) patients showed RV dilation and 27 (25.7%) DVT. Sensitivity and specificity of cardiac US were 91% (95% CI 80-97%) and 87% (95% CI 80-91%) respectively. Venous US showed a lower sensitivity (56%, 95% CI 45-60%) but higher specificity (95%, 95% CI 88-99%) than cardiac US (both p<0.05). When cardiac and venous US were both positive (22 out of 105 patients, 21%) the specificity increased to 100% (p<0.01 vs cardiac US), whereas when at least one was positive (54 out of 105 patients, 51%) the sensitivity increased to 95% (p=0.06 vs cardiac US).

Conclusions: Focus cardiac US showed high but not optimal sensitivity and specificity for the diagnosis of PE in patients presenting with shock. Venous US significantly increased specificity of cardiac US, and the diagnosis of PE can be certain when both tests are positive or reasonably excluded when negative.


Peiman NAZERIAN, Giovanni VOLPICELLI, Alessandro LAMORTE, Chiara GIGLI, Linda FALLAI, Elisa CAPRETTI, Stefano GRIFONI, Simone VANNI (Florence, Italy)
08:30 - 17:40 #10761 - Diagnostic and therapeutic dilemmas: severe vitamin B12 deficiency versus thrombotic thrombocytopenic purpura.
Diagnostic and therapeutic dilemmas: severe vitamin B12 deficiency versus thrombotic thrombocytopenic purpura.

Introduction

Vitamin B12 deficiency is relatively common, particularly in people aged more than 60 years. Most patients with vitamin B12 deficiency do not present with critical condition; however, microangiopathic hemolytic anemia with thrombocytopenia should be noted as a particularly important complication of vitamin B12 deficiency for clinicians working at emergency departments because its presentation seems similar to thrombotic thrombocytopenic purpura (TTP).

Case

An 80-year-old Japanese woman with a history of post-total gastrectomy for gastric cancer 20 years prior was presented with transient loss of consciousness. Her conscious level and vital signs were within normal, and remarkable bruising on her right periorbital area and right lower leg. Blood test showed a decreased hemoglobin level of 6.1 g/dL with elevated mean corpuscular volume of 122.6 fl, relatively low reticulocyte count of 54,020 /μL (3.7 %) and decreased platelet count of 72,000 /μL with 13% of schistocytes. Her creatinine and lactate dehydrogenase levels were elevated (1.61 mg/dL and 1,575 IU/L, respectively), and urinalysis showed mild microscopic hematuria. Plasma exchange and prednisone were initiated as treatment for TTP. In addition, intravenous vitamin B12 supplementation was also begun because she was also suspected with vitamin B12 deficiency based on her history of total gastrectomy and long-term discontinuation of vitamin B12 supplementation. During one day after first session of plasma exchange, her condition was not worsen and laboratory data were also unchanged. Since her consciousness and general appearance were too good for TTP, vitamin B12 deficiency was suspected as the alternative cause of her thrombotic microangiopaghy like presentation. Plasma exchange was discontinued and intravenous vitamin B12 supplementation was continued. On day four, a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs 13 (ADAMTS13) activity was proved normal (50%), and markedly low level of vitamin B12 (under 50 pg/mL) was also reported, which were consistent with vitamin B12 deficiency and against TTP. Hemoglobin level and platelet count gradually recovered to the level of 10.7 g/dL and 103,000 /μL during first month. At several follow-up visits over three months, she had no recurrence of decreased hemoglobin levels and platelet counts.

Discussion

This case was “pseudo” TTP caused by severe vitamin B12 deficiency. Pseudo TTP was reported to be observed in approximately 2.5% of patients with vitamin B12 deficiency. Compared to TTP, older age, higher platelet counts, lower reticulocyte counts, higher mean corpuscular volume and higher lactate dehydrogenase levels, observed in the present case, were proposed as characteristics of pseudo TTP. However, the initial therapy including both plasma exchange and vitamin B12 supplementation may be a reasonable option in patients suspected with pseudo TTP because TTP is critical condition.


Itsumi KOMORI (Tochigi, Japan), Yukinori HARADA, Kohei MORINAGA, Takanobu HIROSAWA, Taku HARADA, Taro SHIMIZU
08:30 - 17:40 #11834 - Differences in outcomes between patients with community-acquired pneumonia (cap) associated with virus infection p-h1n1 2009 and usual community-acquired pneumonia.
Differences in outcomes between patients with community-acquired pneumonia (cap) associated with virus infection p-h1n1 2009 and usual community-acquired pneumonia.

Introduction: The p-H1N1 2009 virus infection is associated with important complications with CAP being the main one. The p-H1N1 2009 virus pneumonia is associated with increase in hospital admissions and intensive care unit resources, but it is not known whether the prognosis and outcomes in these patients are different from those usually hospitalized for CAP.For six weeks between July and August 2009, coinciding with the peak of the p-H1N1 2009 epidemic, all patients with CAP were tested for p-H1N1 2009 virus infection. Among the 105 patients hospitalized for CAP, 53 had p-H1N1 2009 infection and 52 patients had CAP. Invasive mechanical ventilation was necessary in 17 patients in the p-H1N1 2009 group (32.1%) compared to 18 patients in the CAP group (34.6%). Vasopressors were necessary in 10 patients (18.9%) of the p-H1N1 2009 group and 13 patients in the CAP group (25%). In-hospital lethality was 9.4% in the p-H1N1 2009 group and 17.3% in the CAP group. None of the outcomes studied were significantly different between the two groups. The presence of serum LDH> 555 U / L and PaO2


Rodrigo Passarella MUNIZ, Diego Amoroso Garriga REIS (São Paulo, Brazil), Sabrina Correa Da Costa RIBEIRO, Rodrigo Antonio Brandão NETO
08:30 - 17:40 #11169 - Differences in rate of detecting Stenotrophomonas maltophilia depending on the kind of broad-spectrum antibiotics.
Differences in rate of detecting Stenotrophomonas maltophilia depending on the kind of broad-spectrum antibiotics.

Objective: Differences in the rate of detecting Stenotrophomonas maltophilia (S. maltophilia) in sputum culture tests during treatment for infectious diseases depending on the type of broad-spectrum antibiotics are unknown. To assess whether there are differences, we compared groups of patients who were administered broad-spectrum antibiotics. Methods: We conducted a retrospective observational study in the ICU using Piperacillin/Tazobactam (PIPC/TAZ), fourth-generation cepharosporin (ceph4), or carbapenem for the treatment of infectious diseases. We enrolled patients aged 18 years or older who underwent sputum culture tests. The primary outcome was the difference in the odds ratio of S. maltophilia based on the tests. The secondary outcome was mortality. Results: The regression model showed a significant decrease in the detection of S. maltophilia in the PIPC/TAZ group, with a detection rate ratio of 0.108 (p=0.0164), a non-significant increase or decrease in the ceph4 group, with a detection rate ratio of 2.73 (p=1), and a significant increase in the carbapenem group, with a detection rate ratio of 10.5 (p=0.0104). ICU mortality involved 3 patients in the S. maltophilia group (25%), and 6 patients in the non-S. maltophilia group (8.22%) (p = 0.08). The 90-day mortality involved 4 patients in the S. maltophilia group (33.3%), and 22 patients in the non-S. maltophilia group (30.1%) (p = 0.824). Conclusion: In the PIPC/TAZ group, the detection rate ratio of S. maltophilia in the sputum culture was significantly reduced.


Yoshihiro FUJIMOTO (OSAKA, Japan), Kazunobu NORIMOTO
08:30 - 17:40 #10929 - Differential diagnosis of abdominal pain in emergency settings by bedside ultrasound.
Differential diagnosis of abdominal pain in emergency settings by bedside ultrasound.

Purpose: Abdominal pain is one of the symptoms which most often brings patients to the Emergency Room, being nearly 10% of cases. The delay in diagnosis and negative treatment influences the prognosis. Abdominal ultrasound is a fast, portable, repeatable, cheap and non-invasive method, that can provide abundant information to the emergency physicians.

Materials and Methods: Case study of the diagnosis of a splenic infarction using an ultrasound scan performed by the emergency physician.

Results: 56 years old male, former drug injecting addict, fully weaned for years, with HIV infection stage C3, with co-HCV infection, good adherence of antiretroviral therapy, maintaining undetectable viral load and CD4 count of 142 cells/uL, attended the emergency room with abdominal pain on the left side, initially labelled as renal colic. The patient was clinically stable, the laboratory results and radiography were normal, but the patient did not respond adequately to analgesic treatment, so the emergency physician performed a point-of-care ultrasound scan, observed a triangular image with peripheral base, hypoechoic inside the spleen, this data was compatible with splenic infarction,  the patient was left in observation and anticoagulated. The evolution was favorable without further complications and he was discharged from the hospital a few days after admission.

Conclusions: Ultrasound in the Emergency Room is a powerful tool, which together with its low cost and the absence of any adverse effects, is essential in our daily clinical practice. This is not to discuss the indications, in an urgent context of a classical ultrasound that requires high professional qualifications that must be performed by an experienced sonographer and involves the use of a high-end equipment; but we firmly believe in this resource as an extension of the  emergency physician hand and it would be very beneficial to integrate the ultrasound in the medical process of determining diagnosis for urgent diseases.

 


Alberto Ángel OVIEDO GARCÍA (DOS HERMANAS (SEVILLA), Spain), Francisco LUQUE SÁNCHEZ, Margarita ALGABA MONTES
08:30 - 17:40 #11079 - DIFFERENTIAL DIAGNOSIS OF ARTHRITIS IN THE EMERGENCY DEPARTMENT.
DIFFERENTIAL DIAGNOSIS OF ARTHRITIS IN THE EMERGENCY DEPARTMENT.

Female patient, 37 years old, no medical history of interest. Patient was admitted to the emergency room by right ankle acute inflammation. She had diarrheal stools two weeks ago, without pathological products, and self-limit in the time. She did not report any tryps abroad, insect bite or traumatism. No other symptoms were related.

Clinical examination: Cardyopulmonary auscultation did not reveal any alterations. General examination was normal except a red right ankle and increased temperature. The right foot did not show oedema and distal pulses were present. Blood test showed 13300 leukocytes (with left upper shift) with PCR 33. Blood coagulation and biochemistry were normal.

Chest X-ray and electrocardiogram did not show any alterations. A clinical ultrasound was maked in the right ankle, but didn’t show articular effusion susceptible to arthrocentesis for diagnosis. Patient was diagnosed with right ankle acute monoarthritis.

The differential diagnosis of the acute monoarthritis in emergencies should include:

-  Infectious disease: septic arthritis (Staphylococcus Aureus and Mycobacteria), viral arthritis (chickenpox, parvovirus B19) and postinfectious arthritis. The postinfectious disease occurs after an extraarticular infection. Among the arthritis postinfectious´ causes include infection by Brucella or Borrelia, and secondary gastrointestinal infection by Salmonella, Shigella or Yersinia.

-   Inflammatory: Arthritis juvenile idiopathic

-   Trauma

-   Coagulopathies

-   Tumor: bone tumor (osteoid osteoma) or synovial (synovial hemangioma)

-   Other as Behçet disease, sarcoidosis or bacterial endocarditis.

In our case, articular effusion was not present, so arthrocentesis was not done.

However, the patient had gastrointestinal previous disease. Serology blood test was positive for Yersinia enterocolitica. No antibiotics treatment was adminiterred because diarrhea stopped two weeks ago, so symptomatic treatment was administred. antibiotic treatment with ciprofloxacin is required in cases of overlap both symptoms (diarrhea and arthritis)

CONCLUSIONS

Acute Monoarthritis is a medical emergency. It is essential to make differential diagnosis based on age, patient history (previous infections), and epidemiological environment. Extrarticular bacterial infections could cause Acute Monoarthritis.


Enrique CARO-VÁZQUEZ, Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA, Enrique CARO-VÁZQUEZ (MALAGA, Spain)
08:30 - 17:40 #11305 - Dilated Cardiomyopathy detection in the Emergency Department (ED) with Point-of-Care Ultrasound (POCUS): series of six patients.
Dilated Cardiomyopathy detection in the Emergency Department (ED) with Point-of-Care Ultrasound (POCUS): series of six patients.

Introduction

Dilated Cardiomyopathy (DC) is defined as dilatation of cardiac cavities predominant on left ventricle (LV) with an alteration of systolic function without identified cause (valvular, ischemic or hypertensive). Etiologies are viral, toxic but remain frequently unknown. Early identification in the ED using POCUS allows to begin the medical treatment and to hospitalize patient in cardiology. We report a series of six patients who were detected.

Patients and methods

As part of our policy, a POCUS was done with a Philips CX50 for the evaluation of dyspnea when usual clinical procedure was inconclusive. It included a morphological analysis, measurement of ejection fraction (EF) and shortening fraction (SF), valvular insufficiency screening with color Doppler, measurement of aortic velocity time integral (VTI), evaluation of LV filling pressure with mitral Doppler and Doppler tissular imaging (DTI). VTI was chosen because it is a major component of the cardiac output and his measure has good reproductibility. Patients with DC were identified, main clinical features were analyzed. Data were stored on LibreOffice Calc.

Results

Six patients were identified between January 2016 and January 2017, 4 men and 2 women, mean age 47 + 17 years old. Lung auscultation was normal in 4 and revealed crackles in 2. Chest X ray showed lung edema in 3, was normal in 3. ECG was normal in 4 patients, revealed a left ventricular hypertrophy in 1 and an atrial fibrillation in 1.

POCUS showed a dilated left ventricle (65 + 10 mm, n < 55 mm), a mitral insufficiency in all patients, a marked altered left ventricle systolic function (EF 28% + 6 (n>60%), SF 13% + 2 (n>25%)). VTI was low in all patients, 11 cm + 1.5 (n > 14 cm). Left ventricle filling pressures were normal in 3 patients (E/E’ < 8) and elevated in 3 (E/E’ > 14). Furosemide was prescribed and all patients were hospitalized in cardiology.

Discussion

DC is rarely detected in the ED and its prevalence in Emergency Medicine is unknown. Clinical presentation is frequently confusing since 3 out of our 6 patients had normal exam, ECG and chest X ray. Their only complain was a dyspnea during physical activity while they were comfortable at rest.POCUS can play a major role in theses patients. Early detection allows to initiate treatment and might prevent complication such as ventricular fibrillation.


Philippe LE CONTE (Nantes), Philippe PES, François JAVAUDIN, Julien LE MOULLEC, Eric BATARD
08:30 - 17:40 #10968 - Diplopia as a symptom of onset of tuberculosis, an unusual and severe clinical presentation: a case report.
Diplopia as a symptom of onset of tuberculosis, an unusual and severe clinical presentation: a case report.

The tuberculosis is a disease stable in terms of epidemiology, which in recent years has experienced a slight increase due to various factors like HIV, immigration. Although the pulmonary presentation is the frequentest (13,5 / 100.000 inhabitants), the extra-pulmonary presentation occurs in 10-40 % of total cases and varies with age, ethnic group, comorbidity and causal mycobacterium.

The TBC miliar is the haematological dissemination of tubercle bacillus and can be shown as a primary manifestation or early-late reactivation. Clinical presentation is varied. In most cases of TBC miliar culture of sputum are negative and to achieve the best performance is normal to use invasive studies. As happens in our case, the association with tuberculoma is not usual.

The clinical presentation varies, and can be expressed as acute confusional state, symptoms of raised intracranial pressure such as in the case reported. Cerebrospinal fluid tests are usually normal and imaging tests (MRI, CT scan..) gain particular relevance for the diagnostic suspicious and for evaluating  the response to treatment.

Sometimes biopsy is needed to confirm the diagnosis, but in our case the radiological and clinical response was satisfactory. The surgical treatment for these injuries is complex so conservative treatment is preferred, unless there is a obstructive hydrocephalus or symptoms of serious compression.

This case highlights how nonspecific clinical can be in a pathology potentially lethal which requires early diagnostic confirmation to initiate treatment as soon as possible.

We report a case of 20 years old woman migrated from Rumania. Non specific allergies and had not been subjected to any treatment. Was admitted to our Emergency Room for an clinical picture one week evolution with symptoms of weakness and horizontal diplopy which was more evident when eye strain to the left-hand side.

On admission in the Emergency Department the physical exam showed only paresis of the sixth cranial nerve of the left eye. The rest of physical exam was normal. The analytical sample was normal, Chest X-Ray with nodular interstitial pattern bilateral , Brain CT-scan shows multiple intraaxial SOL (space occupying lesions) supra and infratentorials with associated edema which increases after contrast administration and suggests an infectious process as first option and less probable a multiple metastatic disease.

The patient was admitted to the Hospital to complete the study. HIV was negative, lumbar puncture was normal and thoracoabdominal CT scan showed moderate hepatosplenomegaly and micronodular pattern in both lungs. Lastly with the bronchoalveolar lavage was isolated Micobacterium Tuberculosis.

With an initial diagnose of miliar tuberculosis and probable tuberculomas, was initiated treatment with Rifampin, Isoniazid, Pyrazinamide and Ethambutol associated with corticoids. Tolerance was good and the radiological progress of brain injuries was successful. 


Beatriz SIERRA, Pedro VALDRÉS, Maria Peña LOPEZ (ZARAGOZA, Spain), Francisco Jose RUIZ
08:30 - 17:40 #11877 - Disaster Education: A Survey Analysis of Disaster Medicine Training in Emergency Medicine Residency Programs in India.
Disaster Education: A Survey Analysis of Disaster Medicine Training in Emergency Medicine Residency Programs in India.

Study/Objective:

The study aims to assess the level of disaster medicine education in emergency medicine (EM) residencies in India through:

1)   Identifying the disaster medicine competencies addressed by EM training programs

2)   Determining the time spent on disaster training

3)   Comparing opportunities available among different EM programs

Background:

The Medical Council of India (MCI) has no standardized requirements or guidelines for EM training programs on incorporating disaster medicine into the curriculum. Despite a growing political and educational interest in disaster medicine in India, it is unclear if resident training curricula have been amended to reflect these educational goals locally. 

Methods:

A Web-based survey will be distributed from May 15th, 2017 to August 31st, 2017 to all postgraduate emergency medicine training programs listed by MCI, National Board of Examinations (NBE-DNB), Royal College of Emergency Medicine (RCEM), and Society of Emergency Medicine in India (SEMI). The survey will be targeted towards Emergency Department Heads, senior faculty, and postgraduate trainees. The survey tool will collect information regarding the program, location, type of hospital, duration of program, role of survey responder, disaster medicine competencies address and teaching methods used. Disaster core competencies assessed will include those recommended by the National Standardized All-Hazard Disaster Core Competencies Task Force in 2012.

Results:

The study is ongoing. The authors hypothesize that there will be a variety of competencies taught across residency programs in the absence of standardized curricula.

Discussion:

Emergency Physicians are at the forefront of responding to major disasters. Without a standardized curriculum in disaster medicine, however, many may lack the core competencies required for operating in disaster situations. Through understanding individual views on and the current state of disaster medicine training we hope to provide targeted guidance for disaster medicine education in Indian postgraduate EM training programs.


Srihari CATTAMANCHI, Ritu SARIN (Boston, USA), Amalia VOSKANYAN, Ramakrishnan TRICHUR, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11850 - Disaster Medicine fellowship websites: If you build it, they will come.
Disaster Medicine fellowship websites: If you build it, they will come.

Study/Objective:

To differentiate between the websites of non ACGME Disaster Medicine (DM) fellowships in the United States (US) by analyzing objective data including:

program length,

prerequisites,

disciplines offered,

curricula taught,

rotations (optional/mandatory)

and utilization of blended/hybrid education. 

Background:

In 2016 the Society for Academic Emergency Medicine (SAEM) listed 17 US Based Disaster Medicine (DM) fellowship programs.

DM is an emerging subspecialty of Emergency Medicine that is evolving rapidly; within its domain DM is developing specialty concentrations such as counter-terrorism medicine, protective medicine and humanitarian medicine alongside what is traditionally seen as the ‘blue lights’ of DM the disaster response element itself.

There is no nationally approved standardized curriculum. 

Methods:

A comprehensive evaluation of publicly available data on websites of SAEM listed US DM fellowship programs.

A data abstraction instrument was used, data was captured and analyzed in Microsoft Excel.

Simple statistics were used to display data in graphical form or tables. 

Results: 

The duration a program has been operating can indicate stability of a non-ACGME program. The majority of programs (13) do not publish data on how long they exist the oldest program has been educating candidates for 10 years, with the most recent for four years.

Listed program faculty members ranged from 1 – 41 (n=11). The number of faculty can indicate breadth of specialist experience available and potential educational experience attainable in the program.

DM is a subspecialty with worldwide interest; for international candidates it may not be possible to pursue a fellowship program in their country of origin, publishing whether a program accepts international candidates would be beneficial on a programs website.

Rotations both mandatory/elective can ensure fellows are exposed to as broad a range of the phases of DM both within program institution and outside response agencies such as CDC, FEMA, FDNY.

Understanding instructional methodology is also a key component which should be available to candidates when choosing a program. It is vital when on external rotation to be able to continue to participate in home based didactics utilizing blended learning and flipped-classroom approach.

DM fellowship programs also offer additional concentrations to enhance fellows leadership capacity, ability to respond to humanitarian crises, understanding of EMS systems, and understanding of what is involved in the growing area of counter-terrorism medicine. 

Conclusion:

Considerable work is required by the majority of US DM Fellowship programs to develop guidance for candidates regarding their programs offering.

An agreed curriculum is urgently required to standardize training in this era of growing terror threat.

Future candidates have a growing number of programs available, there is a need for an aggregated source of information to enhance program choice. 


Taha MASRI, Abdulla ALRASHIDI, Maryam ARSHI, Amalia VOSKANYAN, Ritu SARIN (Boston, USA), Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11329 - Diskitis- A rare Diagnosis in a common complaint.
Diskitis- A rare Diagnosis in a common complaint.

Diskitis masquerading as lumbosacral spine sprain/ strain.

Dr Naser Mohammed Ali Mansoor Emergency physician, Salmanyia medical complex, Bahrain.

Diskitis is a condition where there is an infection in the intervertebral disc space which can lead to severe consequences like sepsis and epidural abscess. The infrequency with which it is encountered and the very common presenting complaint it is associated with makes diskitis a formidible diagonstic challange.

A 37 yrs old male was brought from the local jail with the complaint of lower back pain for the past 4 days. this started after he had lifted some heavy object and was temporarily relieved by NSAIDs. The referring clinic diagnosis was " persistant lower back pain for evaluation". The patient was vitally stable with a low grade fever of 37.8 C . Initial examination revealed a well built male with mild lower back pain on movement. straight leg raising was >60 bilateral. He was mildly tachycardic with a pulse rate of 101 and room air saturation of 97%. the patient denied any drug or alcohol abuse. On examination there was bony tenderness over the L2 till L5 discs. This raised the suspicion of a more serious cause for this presenting complaint and a plain x-ray was obtained which showed disc space narrowing and ill-defination of the vertebral endplates. At this point the patient requested that he wanted to take some strong pain killers and wanted to be discharged. His accompanying guards were also of the same opinion as it was their shift change time. The initial blood reports showed an ESR of 82 and a white cell count of 31,000. The patient was explained the concerns of severe health risks of the working diagnosis of spondylodiskitis and he consented to stay. He was started on broad spectrum antibiotics and an MRI was obtained which confirmed the diagnosis. By this time the patient confessed to have being using IV drugs upto the past 2 months when he was arrested. An echo cardiography was obtained showing gross vegetations of the Tricuspid and Aortic valves. He was consequently admitted to the ICU. A week later he developed shortness of breath and a pneumothorax for which he received a chest tube. Ct of the lung at that time showed multiple cavitatory lesions due to septic emboli. The patient endured a rough course in the hospital for the next 3 months , wherein he was twice intubated. He eventually had a favourable out come and was discharged after 112 days in the hospital.

The case illustrates the potential for severe consequences in a very common presenting complaint in the emergency department.It highlights the value of a thorough physical exam and recognition of red flags ( bony tenderness, tachycardia and low grade fever) while approaching the most mundane of presenting complaints. Keeping a wide range of differential is critical to institution of appropriate therapy and prevention of mortality and morbidity.


Nasser Mohammed ALI MANSOOR, Nasser Mohammed ALI MANSOOR (Manama, Bahrain)
08:30 - 17:40 #11215 - Dislodged right atrial lead of pacemaker, early picked up in ED.
Dislodged right atrial lead of pacemaker, early picked up in ED.

Dislodged right atrial lead of pacemaker, early picked up in ED

Introduction:

Pacemaker lead displacements can be defined as any other pacemaker position change, whether the functionality of the pacemaker is affected or not. However, only those displacements that provoke a malfunction in the pacing system are clinically relevant. (1)

Radiology plays a crucial role in initial assessment and follow-up of cardiac conduction devices (CCDs). At least 1 million patients in the United States have permanent CCDs, which comprise pacemakers and implantable cardioverter-defibrillators. Chest radiography is unique because it is the only imaging modality that allows evaluation of the physical integrity of CCD leads (2)

Case presentation:

A 68-year-old man was admitted in April 2017 with dyspnea, mild dizziness, after recent discharge from the hospital (one week before) due to permanent pace maker inserted after developing Mobitz II AV block. He had a history of coronary bypass surgery 20 years ago.

 Electrocardiogram showed Ventricular paced rhythm only although on reviewing his previous x rays there was atrial and ventricular leads (dual chamber pacemaker), on repeating the X ray there was change of the atrial lead position with loss of the j shaped position to straight downward one. The Cardiologist was alerted at once. At follow-up, pacemaker analysis showed no atrial sensing and pacing. Programming the pacemaker to VVIR mode did not relieve symptoms, and the patient was scheduled for repositioning of atrial lead, which was performed the next day and the patient discharged from hospital after relieving of his symptoms.

Discussion:

 Early dislodgment of atrial lead was reported in 2.9% of cases. (3) Possible causes of lead dislodgment include lead design, operator experience, abnormal atrial anatomy, and mechanical problem of the screw-in system cause of early dislodgment of screw-in leads. (4) Lead dislodgement requiring reoperation is a complication that raises the costs of pacemaker implantation surgery, while adding to patient discomfort. Dislodged lead can cause complications such as under sensing, loss of atrial capture, and loss of atrial function in patients who need AV synchrony. Once detected, the dislodged lead should immediately be repositioned. (5,6) 

Conclusion:

Emergency physician should be alerted and keep the possibility of pacemaker lead dislodgment in his differential diagnosis list.

References

1.       Chauhan A, Grace AA, Newell SA et al. Early complications after dual chamber versus single chamber pacemaker implantation. Pacing Clin Electrophysiol. 1994; 17:2012-2015.

2.       Amanda L. Aguilera, MD, Yulia V.et al. Radiography of Cardiac Conduction Devices: A Comprehensive Review. 2011, 31:1669–1682


Ramy ABDELKADER (Cairo, Egypt)
08:30 - 17:40 #11702 - Disposition safety as a quality indicator at the Paediatric Emergency Department.
Disposition safety as a quality indicator at the Paediatric Emergency Department.

Introduction: one of the main objectives is the recognition and immediate treatment of the critically ill children at the Paediatric Emergency Department (PED) and the transferring them to the Paediatric Department (PD) or Intensive Care Unit (ICU) depending on their conditions and vital parameters. In the cases of those patients that were transferred from PD to ICU during the first 24 hours of treatment (F24T), the recognition and/or treatment was insufficient. The survey of this patients' number / ratio can be a quality indicator for the paediatric emergency care.

Patients: We compared the patients' data, who were admitted from  01.01.2005 to 31.12.2006 (408 patients) with those who were admitted from 01.01.2015 to 31.12.2016 (564 patients) on ICU in Heim Pal Children's Hospital, Budapest, Hungary. The Paediatric Emergency Department was established in 2007, therefore during the first period the admissions were indicated by a general paediatrician, who worked on "outpatient clinic" in the hospital.

Methods: the surgical / orthopaedics / ENT cases were excluded from this study. Our hospital is a tertiary medical centre, therefore those patients who were transferred from other hospital were also excluded. We analysed the patients ratio requested admission to the ICU in F24T. We compared the length of stay (LoS) in ICU and in hospital among the next three group (1: directly admitted (DA) from the outpatient clinic; 2:  transferred from another department in F24T; 3: during a late period of treatment.)

Results: 110 children were admitted who met the criteria during 2005 and 2006. 17 patients (15.45%) directly from the outpatient clinic, length of stay (median, [min;max]) was 2.75 day [1;6]. 93 patients (84.54%) were transferred from another department, 32 (29%) of them were in the F24T. The median LoS in the F24T group was 6.5 day [1;23]. Between 2015 and 2016 157 patients met the criteria and were hospitalised. 106 patients were admitted directly from the PED, the mean LoS was 2.41 day [1;22] in this group. 51 (32.5%) patients were transferred from another inpatient  unit of hospital, 15 (15.92%) of them during the first 24 hours. The mean LoS was 3.84 day [1;21] in this group.

Conclusion: there was a significant differences (p<0.005) between the LoS of DA group and the others. The authors' opinion is that disposition and the intrahospital transfer on the ICU are an appropriate quality indicator for the paediatric emergency care.


Zsolt BOGNAR (Budapest, Hungary), Viktoria ABONYI, Szilvia CSORBA, Xenia MAJOROS, Marianna FEJES, Gabriella KISS
08:30 - 17:40 #11338 - Distant Trigger.
Distant Trigger.

A 78-year-old male with recently diagnosed with rectum adenocarcinoma pending on surgery comes to the Emergency Department complaining of dysarthria and deviation of the labial commissure since he woke up.

On physical examination, the patient appears to be in good general condition, Blood pressure 115 / 57mmHg with a Heart rate 75 bpm. Temperature 38 Celsius (100.4 Fahrenheit). He presents left central facial paralysis with mild dysarthria and mild paresis, pronounced in proximal left limbs. No other relevant findings.

Analytics shows Hb 9g/dl, CRP 4.89 mg/dl, Prothrombin activity 71%. The electrocardiogram is in sinus rhythm without any alteration. 

Urgent Head CT is performed and shows anterior insular cortical-subcortical hypodensity, suggesting an acute ischemic event in right MCA territory. 

Given the unknown time since the onset of the symptomatology and after consulting with the neurologist, we decide conservative treatment. 

After evaluating the patient, he presents an aortic systolic murmur and presents with febrile peaks up to 39.5 Celsius (103.1 Fahrenheit).

When we suspect bacterial endocarditis, an echocardiogram is requested and the clinical suspicion of mitral and aortic endocarditis with associated valvular dysfunction is confirmed. Cultures are done evidencing Gram-positive cocci in chains. We initiate then empirical treatment with Ampicillin, Cloxacillin, and Gentamicin. 

Clinical diagnosis: Ischemic stroke in probable relation to septic embolism due to bacterial endocarditis.

During admission, the growth of streptococcus sanguineous is confirmed on the blood cultures. 

The patient situation complicates with a broncho-aspiration, a seizure and a subarachnoid hemorrhage with a decrease in the level of consciousness triggered by the rupture of a mycotic aneurysm. Given the patient's clinical situation and patient's comorbidities is rejected for Surgery. Finally, he dies the seventeenth day of admission. 

Conclusions: 

Neurological complications of infective endocarditis are sometimes the first clinical symptomatology of the disease and are associated with a significant increase in mortality. The main form of presentation is an embolic stroke. 

The main risks factor for embolization are delayed initiation of antibiotic therapy, left cavities location, vegetation size >10 mm, and S.aureus and Streptococcus Bovis etiology. In any way, early diagnosis and early initiation of antibiotic therapy are the most effective tool to improve prognosis.


Isabel FERNÁNDEZ-MARÍN (Madrid, Spain), Víctor SÁNCHEZ ALEMANY, Francisco JIMÉNEZ MORILLAS, Ismael GARCÍA DEL PINO, Luz Tamara VAZQUEZ RODRIGUEZ, Luis PÉREZ ORDOÑO, María CUADRADO FERNÁNDEZ
08:30 - 17:40 #11112 - Do suicidal patients jump off higher places than patients who are not suicidal?
Do suicidal patients jump off higher places than patients who are not suicidal?

INTRODUCTION

After a fall, the distance fallen is sometimes used to predict the injury severity. But there are few references discussing suicidal ideation after a fall from a height. The aim of this study was to clarify whether suicidal behavior can be inferred from any clinical factors available on admission.

METHODS

Between January 2011 and December 2015, the medical charts of patients who intentionally jumped from a height, attended our emergency department, and survived were reviewed.  Based on the psychiatrist’s interview, patients were divided between a suicidal group (S+) and a non-suicidal group (S-).  Schizophrenic patients were excluded, because their attempts are usually associated with hallucination or delusion.  Patients’ characteristics, height of fall and hardness of ground were analyzed using Fisher’s exact test or the Mann-Whitney U test.

RESULTS

Forty patients were included.  Among them, 13 (31%) were S+.  There was no difference in age, sex, underlying psychiatric disorders or injury severity score.  The median height of fall was higher in the S+ group (12 m) than in the S- group (9 m) (p = 0.002). In the receiver operating characteristic curve for the prediction of suicidal behavior based on height of the fall, the area under the curve was 0.793. The optimum cutoff value was set at 11 m. Using this value for predicting suicidal behavior, the sensitivity and specificity were 69% and 86%, respectively. There was no difference in hardness of the ground. But, all cases jumping from lower than 11 m to a soft surface such as soil or grass were in the S- group.

CONCLUSION

The height of the fall is a good predictor for suicidal behavior in jumping from a height.


Shota KIKUTA (Yes, Japan), Satoshi ISHIHARA, Keisuke MAEDA, Shinichi NAKAYAMA
08:30 - 17:40 #11020 - Do the victims of stroke benefit from all the same time deadlines between the alert and the carrying out of the brain imaging? Prospective observational study.
Do the victims of stroke benefit from all the same time deadlines between the alert and the carrying out of the brain imaging? Prospective observational study.

Introduction: The quick access to brain imaging is essential in the support of the cerebrovascular accident (stroke) to confirm the diagnosis and the origin; the patient must be addressed directly in the Neurovascular unit (NVU). In case of the impossibility of a direct admission, the patient would then be taken to a nearby emergency room (ER) within a hospital equipped or not with a NVU. The aim of this study was to measure the median time for the brain imaging in stroke patients transported to the nearest hospital, and to compare this time according to whether this hospital was equipped or not with a NVU. 

 

Materials and methods: Prospective non-interventional observational study. Inclusion criteria: victims of stroke > 18 years, cared for by first aid professionals in a metropolis of high population density and sent to the nearest ER facility. The data collected focused on the age, sex, the time of the emergency call ("alert"), the median time from first alert to brain imaging (" imaging "), whether or not there was a NVU within the hospital of destination. The primary endpoint  was the delay between the first alert time and the time of the imaging. The statistic estimators were the percentage for the qualitative variables, and the average (standard deviation), or the median [interquartile range IQR ] for the quantitative variables.  Statistical analysis was univariate.

 

Results: From the 1st to the 30th June 2015, 78 patients were included. The average age was 68+ 15 years with 38 (48.7%) men. Fifty-six patients have been sent to a hospital with a NVU, versus 22 without a NVU.  The median delay time for "first alert - imaging" was 400 min IQR [234-541] for patients transferred to an ER in a hospital without a NVU, versus 307 min IQR [150-599] for those directed to an ER in a hospital with a NVU.

 

Discussion: Among the patients with a stroke and who did not benefit from a first-line NVU, the absence of a NVU in the receiving hospital was associated with a lengthening of the median delay of "alert-imaging" by 107 minutes. The absence of a predetermined procedure in some hospitals not equipped with a NVU, or the logistical difficulty of access to the imaging are explanatory factors in this exploration. The study goes on with a view to propose corrective actions at all levels of care.


Laure ALHANATI, Isabelle KLEIN (PARIS), Stéphane DUBOURDIEU, Jimmy ROBERT, Alain COURTIOL, Michel BIGNAND, Jean Pierre TOURTIER
08:30 - 17:40 #11671 - Do we need new guidelines for handling head trauma cases at Sibiu hospital?
Do we need new guidelines for handling head trauma cases at Sibiu hospital?

BACKGROUND

Nowadays, the human life is characterized by new activities that expose people at different trauma risk like action sports, driving cars, etc. A lot of head trauma are characterized by injuries that seem minor and don't require medical specialized attention.

But, sometimes minor head injuries may cause persistent chronic symptoms, such as headache or difficulty concentrating, and you may need to take some time away from many normal activities to get enough rest to ensure complete recovery. Taking into account of these symptoms is mandatory, as  the medical condition of someone with this injury can deteriorate in time.

 

Meticulous observation and fast action could identify those head injuries that have chances to evolve to a worse medical status. The aim of this study is to put into light the clinical profile of visual complications in patients attended by Sibiu hospital.

.

METHODS

Data for this study is taken from Sibiu Emergency Hospital database, for a period of 3 years.  Head injuries cases are selected in otder to analyze the complications and the very first important maneuvers to asses this injury.

 

RESULTS

Eyes, neurological and facial complications occurred in most of the cases. A greater degree in incidence was found in males comparing with females. The causes of second stage complications in all these trauma cases  are  met in all kinds of accidents like work accidents, road accidents, fights and other types of trauma. In a higher degree, pedestrians are more affected than drivers having more complications in traffic accidents.

 

CONCLUSIONS:

For sure is that head injuries remain one of the most common cause of complex impairment on different sites, evolving with  a life-long disability. Fortunately, most of them can be prevented or theirs effects to be reduced by  implementing a prioritized set of trauma guidelines for all head injury patients in the very first stages of advanced medical care in hospital and pre-hospital. In the end our  study highlights the importance of such protocols for Sibiu hospital to reduce the impact of these unfortunate situations.

 


Marius SMARANDOIU (Sibiu, Romania), Alin CANCIU, Alina Adriana PANGA, Daniela TARAN, Dania LUNCA
08:30 - 17:40 #11046 - Do we underestimate adolescents with infectious symptoms? Diagnostics and management at the emergency department.
Do we underestimate adolescents with infectious symptoms? Diagnostics and management at the emergency department.

INTRODUCTION Adolescents (12-16 years) account for a substantial number of emergency department (ED) visits. They visit the ED with specific problems like trauma and injuries, intoxications and sexual health related problems. However, they also visit the ED with more common emergency problems like infectious symptoms which might have a serious disease outcome. Most of the current literature about infections at the ED focuses on infants and young children. This observational study aimed to assess diagnostics and management of infectious diseases in adolescents presenting at the ED, compared to children (>12 years). 

METHODS The research is based on a prospective observational study at the ED of an university hospital. Data collection consists of routinely recorded patient data extracted from electronic medical records. We included children aged ≤16 years attending the ED with infectious problems (2012-2013). Children and adolescents with complex comorbidity were excluded. We defined three groups of infectious problems: fever, dyspnoea and vomiting/diarrhoea. The associations between age, diagnostics (laboratorial testing, imaging) and management (intravenous (IV) medication, hospital admission) were assessed using a logistic regression model. We adjusted for gender, urgency and type of infectious problem. The results were compared with data from the ED of a general teaching hospital.

RESULTS A total of 6974 children visited the ED of the university hospital, of whom 14.2% were adolescents. Of all children with infectious problems (n=1882), 102 (5.4%) were adolescents. Of all adolescents 52.0% presented with fever, 32.4% with dyspnoea and 15.7% with vomiting and diarrhoea.

Multivariable logistic regression showed that adolescents underwent more imaging (OR= 1.8, 95%CI 1.1-3.0) and received more IV medication (OR= 2.3, 95%CI 1.3-3.8) compared to children <12 years. There was no difference in laboratorial testing (OR=1.0, 95%CI 0,7-1,5). There was no difference in hospital admission between adolescents and children <12 years (OR=0.7, 95%CI 0.4-1.2).

In the general hospital a total of 10758 children visited the ED, of whom 22.5% were adolescents. Of all children with infectious problems (n=2411), 103 (4.3%) were adolescents. Of all adolescents 27.2% presented with fever, 55.3% with dyspnoea and 17.5% vomiting and diarrhoea.

Multivariable logistic regression showed that adolescents underwent more laboratorial testing (OR=4.0, 95%CI 2.6-6.3), more imaging (OR=6.8, 95% 4.2-11.1) and were given more IV medication at the ED (OR=2.8, 95%CI 1.9-4.3) compared to children <12 years. Adolescents were less often admitted to hospital (OR=0.4, 95%CI 0.3-0.5).

CONCLUSION This study showed that adolescents with infectious symptoms presenting at the ED underwent more diagnostics and received more IV medication compared to younger children. The differences in hospital admittance are conflicting. We may not underestimate the severity of infectious symptoms in adolescents.


Arianne P. G. VAN RIJN (Rotterdam, The Netherlands), Joany M. ZACHARIASSE, Dorine M. BORENSZTAJN, Frank J. SMIT, Henriëtte A. MOLL
08:30 - 17:40 #11799 - Do you speak my language?: Refugee experiences in an urban emergency department.
Do you speak my language?: Refugee experiences in an urban emergency department.

Syrian War is one of the most pressing humanitarian crisis in the late history. The war has caused millions of people to be displaced from their homes and forced them to seek shelter as refugees in different countries in Europe, most notably to Turkey due to geographical proximity. It is estimated that there are more than 5 millions of refugees and more than 3 million of refugees are living in Turkey. Although healthcare in Turkey is offered for no cost for the refugees, the healthcare needs of the refugees are not fully met due to language and cultural barriers and patient-centered problems. This caused an extra patient load in already over-crowded emergency departments in Turkey. In our study we aimed to identify how many refugees seeked care in our tertiary medical center emergency department and analyzed the descriptive statistics of the patients and their chief complaints.  We included a total number of 1076 patient encounters taken place in our emergency department over a thirty-five month period. The studies regarding refugees’ health and emergency medicine are sparse and, to our knowledge, our study is the first one to offer in-depth analysis of the daily struggles faced by these patients and their caregivers. 


Salahi ENGIN (Antalya, Turkey)
08:30 - 17:40 #10880 - Doctor I have an injury in the torax. Infiltrant breast cancer.
Doctor I have an injury in the torax. Infiltrant breast cancer.

 

  • Personal history: 81-year-old female HTA under treatment, cholecystectomy and without other antecedents of interest.

 

·         Anamnesis:picture of several weeks of evolution of extreme tiredness and loss of appetite, evident loss of weight and prostration.

 

·         Physical examination: Temperature 37.3ºC, TA: 100/50. Saturation O2: 95%. Affectation of the general condition, generalized mucosal skin paleness. Normal cardiorespiratory auscultation. Abdomen without alterations. In lower limbs no edema, mild signs of peripheral venous insufficiency.
Skin and mucous membranes: ulcerated lesion on the left breast of approximately 10 * 8 cm with irregular borders and bad smell that the patient has covered with several layers of tissues.

 

·         Supplementary tests: Routine analysis with anemia and leukocytosis. Rx thorax: normal cardiothoracic index, no condensations are observed. Several lesions are seen in left costal arches that coincide with the location of the lesion and can be reported as local infiltration of the tumor.

 

·         Clinical judgment: Extensive cutaneous skin infiltration as the first manifestation of breast cancer.

 

·         Treatment and evolution:after hospital admission was included in a palliative care program and entry into this area died within a few days.

 


• Conclusions:
The detection of the fragile elder is a priority theme. Its relevance is marked by a greater probability of presenting adverse episodes, dependence and death, which gives us the potential to try to modify this adverse course. Almost all health services at European level have programs or action plans on the elderly in general, and fragile elders in particular. In our case the patient due to her social problem went to the emergency room when the cancer had already progressed so much that there was no option to fight for her life.

 


Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO, David NUÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11051 - DOCTOR, I HAVE ARM SWOLLEN, WILL BE THE POSITION?
DOCTOR, I HAVE ARM SWOLLEN, WILL BE THE POSITION?

Personal history and reason for inquiry:

Girl of 30 years, with no known allergies. No toxic habits. Peripheral venous insufficiency of lower limbs as a unique background of interest without treatment, works in an office as administrative.

Go to emergency by sensation of swelling in the right arm from 4 days ago, don't remember traumatic history or apparent physical effort. As data of interest tells us that in the last week has been busy, being for hours using the computer at work.

 

Physical examination:

The patient is in good general condition, vital signs normal with blood pressure 110/60. Heart rate 80 lpm. T ° 36.5.

At the AC it presents regular and rhythmic tones. The AR does not present pathological noises. The exploration of upper limbs we observed an increase in size of the right upper limb from hand to axillary area associated with edema and increase in temperature. In lower limbs are observed signs of peripheral vascular failure grade 2.

 

Complementary tests:

In the Emergency Department are requested:

-          Rx thorax: findings of interest.

-          Rx's shoulder and right arm: pathologic images are not observed.

-          Blood analysis: parameters within normal limits except a D Dimer in values of 3,500

-          ECO Doppler Member upper right: right axillary and brachial vein thrombosis.

 

Clinical judgment:

-          Thrombosis vein deep Member upper right.

 

Evolution:

The patient was given discharge from the Emergency Department with oral anticoagulant therapy (acenocoumarol) and low molecular weight heparin. Home monitoring was conducted until picture resolution and subsequent assessment in medicine internal with testing of Autoimmunity being all negative results.

 

 

Conclusion:

We are faced with a young patient without cardiovascular risk factors, without any treatment and whose subsequent studies in search of possible triggering cause of the box were negative. There is another option that think that it was secondary postural factor to multiple hours using the computer at your workplace the trigger of the pathology.


Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO, David NÚÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11016 - Documentation of Preclinical Emergency Care.
Documentation of Preclinical Emergency Care.

Background
Preclinical emergency care in Germany is facilitated by physician staffed or paramedic staffed ambulances. The analysis of routinely documented information on preclinical emergency care could provide important numbers on utilization and utility of physician staffed and paramedic staffed ambulances.

Objective
Description of quality of routine clinical documentation in preclinical emergency care.

Methods
Data of 1,260 patients who presented to the ED of a tertiary care hospital by ambulance within a three months period in 2014 were analyzed. Routinely documented data on preclinical emergency care were manually extracted to an electronic data base. Clinical data on ED and in-hospital care were automatically extracted from the hospital information system and contained demographic data as well as data on ED triage, diagnoses and in-hospital course. The descriptive analysis was conducted in SPSS (Version 23, IBM), 3-digit ICD-codes were analyzed.

Ergebnisse
Of all 1,260 patients, 76.6% received preclinical treatment by paramedics only (n=965) and 23.5% were transported to the ED by physician staffed ambulances (n=295). The emergency location was documented in 73.2% (n=922) of all patients. Of all documented cases the emergency location was an apartment in 57.4% (n=529), a public place in 19.0% (n=175) and `another location´ in 17.9% (n=165) and a medical practice or nursing home in 5.8% (n=53) of all cases. The preclinical urgency was documented in 71.0% (n=894) of all patients. It was documented as `life-threatening´ 2.3% (n=21), `very urgent´ in 8.4% (n=75), `urgent´ in 35.9% (321), `normal´ in 45.7% (n=409) and `non-urgent´ in 7,6% (n=68). Medical measures were documented in 64.0% of all cases, a main diagnosis in 19.8%. Pharmacological therapy was documented in free text fields and not analyzed. Of all patients, 52.7% (n=664) were male and were 43.8% (n=552) were female. 44.8% (n=565) of all patients received inpatient treatment and 1.9% (n=24) died in hospital.

Conclusions
The documentation of preclinical treatment need to be standardized to facilitate valid analysis of preclinical emergency care. An electronic documentation without free text fields and mandatory fields would enable the extraction of valid data for a high number of patients.


Pr Anna SLAGMAN (Berlin, Germany), Johann FRICK, Julia SEARLE, Tobias LINDNER, Pr Möckel MARTIN
08:30 - 17:40 #11105 - Does a routine urinalysis prolong emergency department length of stay?
Does a routine urinalysis prolong emergency department length of stay?

Background: The emergency department (ED) is under pressure to meet length of stay (LOS) metrics for care in the ED. An aspect that we propose affects LOS is the order for urine sample collection and subsequent urinalysis as both are time consuming steps. This project’s primary goal is to determine if ordering a urinalysis (UA) increases LOS. Secondary objectives were to identify factors that contribute to the ordering of a UA, and to decipher if LOS was more impacted in patients who were discharged vs. admitted to the hospital.

 

Methods: Retrospective chart review of consecutive patients who presented to our ED during April 2016. Data were abstracted onto a data collection sheet, with the abstractor blinded to study hypotheses. Variables included whether a urinalysis was ordered, times of urinalysis order and result, who ordered the urinalysis (mid level provider [MLP] vs. physician), whether the urinalysis was cancelled, LOS, age, and gender. Descriptive statistics and multivariable regression analysis were used to analyze relationships between the variables collected and their influence on LOS.

 

Results:

The overall median LOS was 157 minutes, with an interquartile range (IQR) of 81 to 246 minutes.

For discharged patients, it was 142 minutes, with an IQR of 46 to 236 minutes.

For admitted patients, it was 177 minutes, with an IQR of 118 to 260 minutes.

 

Amongst admitted patients, multivariable regression analysis demonstrated that the following factors were associated with increased LOS: first by MLP in triage then physician in main ED (P<0.0001, 95% CI 19.8 - 55.3)

 

Amongst discharged patients multivariable regression analysis demonstrated that the following factors were associated with increased LOS:

  • Seen first by MLP in triage then physician in main ED (P=0.0296, 95% CI 3 - 57)
  • Seen by MLP only (P<0.0001, 95% CI -160 to -106)
  • UA ordered (P=0.0005, 95% CI 20 - 70)
  • Being seen on weekend (P=0.0166, 95% CI -51 to -5)
  • Being older (P=0.0475, 95% CI 0.007 - 1.22)

 

The UA was cancelled in 9% of our patients, and in 60% of cases, these UAs were ordered by the MLP in triage.

 

Conclusion:

Having a urinalysis ordered increased ED LOS, especially in patients who are ultimately discharged. In our ED, routine UAs are ordered more often by MLPs than physicians. Given that 9% have the test eventually cancelled, one should consider the utility in ordering routine UAs in ED patients, as they increase LOS.


Bethany BALLINGER (Orlando), Ambika ANAND, Latha GANTI
08:30 - 17:40 #11566 - Does base deficit at admission predict elevated lactate levels in polytrauma at the emergency department.
Does base deficit at admission predict elevated lactate levels in polytrauma at the emergency department.

Introduction: Lactate and base deficit (BD) are both early biomarkers proposed as clinical tools to identify severely trauma patients admitted to the emergency department (ED). Whereas BD is widely and rapidly available at the emergency room (ER), lactate remains not often possible to drawn in routine. This study aimed to determine if BD rapidly available can predict elevated lactate level in trauma patients admitted to the ER.

Methods: This was a single-center prospective study (33 months). Inclusion of all adult trauma patients admitted to the ER (mechanism and velocity). Lactate and BD measurements were performed on blood samples drawn immediately at admission before any resuscitation. Lactate >=2,5 mmol/l was considered abnormal. Area under the receiver operating characteristic curve for BD to predict abnormal lactate was calculated.  Correlation between BD and lactate was also performed.

 

Results : Inclusion of 479 patients. Mean age = 37+/- 16 years. Sex-ratio 4,2. Median BD (IQR) = -3,2 ( -6, -0,8); Lactate was obtained in 280 patients with average level (SD) = 2,66 (2,2). Other population characteristics: n(%) : Blood pressure <= 90 mmHg : 46(9) ; Glasgow Coma scale <=8 : 110(29); Mortality Day-1: 11(2); Mortality Day-7: 84(19); ISS>15: 320(69); BD < -3 mmol/l : 246(51); Lactate >=2,5mmol/l : 105(22). Characteristics of ROC curve for BD to predict abnormal lactate level were: AUC = 0,755; p<0,001; BD cut-off value < -3 mmol/l; sensitivity= 75%; specificity = 62%; negative predictive value = 81%. Furthermore, correlation was found between BD and lactate  ( Rho spearman = -0,5 ; p < 0,001).

 

Conclusion : In this study, BD seems to be a rapid and useful marker to predict elevated lactate. Moreover correlation was found between tested biomarkers.  Thus, BD could be proposed for early triage and identification of trauma patients with urgent need to more aggressive resuscitation. Enlargmement of the cohort’s sample to multicentric study could ameliorate the sensitivity of our results.


Hamed RYM (Tunis, Tunisia), Imen MEKKI, Sarra JOUINI, Aymen ZOUBLI, Houssem AOUNI, Alaa ZAMMITI, Abir WAHABI, Chokri HAMOUDA
08:30 - 17:40 #9840 - Does Point of Care Peripheral Venous Blood Gas, predict re-presentation in the elderly patients to Emergency Department?
Does Point of Care Peripheral Venous Blood Gas, predict re-presentation in the elderly patients to Emergency Department?

Background: The peripheral venous blood gas (PVBG) is often performed in the emergency department for multiple reasons. It is costly and may be useful in some time-critical conditions but may be over-utilised in some patients. Its use in risk prediction of re-presentation of elderly patients with normal vital signs and non-specific presenting complaint is uncertain.

Aim: To determine if abnormal PVBG parameter abnormalities correlate with re-presentation within 72-hours in patients 65 years or older discharged from the ED with normal presentation vital signs.

Method: Retrospective audit from Jan 2011 to Dec 2015 of the electronic medical records of three EDs of Monash health. All haemodynamically stable patients >65 years-old who had a VBG performed on presentation were identified. Clinical and VBG characteristics of those re-presenting within 72-hours post-discharge were compared to those not re-presenting (control group). Comparisons included age, discharge diagnosis, pH, pCO2, bicarbonate (HCO3⁻), base excess (BE), blood glucose (BSL), serum sodium (Na), potassium (K), chloride (Cl⁻) and lactate (Lac).

Results: There were 723 presentations meeting inclusion criteria, with 127 (18%) re-presentating within 72-hours. Median age of the groups was similar {77 (IQR:71-83) vs 76 (IQR:70-83)} as was gender (50% female in both groups).The Vital signs, as well as the most common presenting complaints, were similar in both groups: dyspnea (20% v 18%) and abdominal pain (16% v 13%).  A lower mean base excess (1.47 v 2.22 ; p 0.009) and hypokalaemia ( 4.02 v 4.18 mmol/L ; p 0.01 ) were seen in the re-presentation group. There were no differences in other VBG parameters between the two groups.

Conclusion:

Analysis of venous blood gas testing showed there may be is an association between low base excess (BE) and hypokalaemia with higher incidence of unexpected re-presentation of otherwise haemodynamically stable elderly patients within 72 hours of their index visit.


Dr Pourya POURYAHYA (Melbourne, Australia), Jinghang LUO, Andis GRAUDINS, Alastair MEYER
08:30 - 17:40 #11866 - Does Procalcitonin impacted antibiotic prescription during Foodborne illness.
Does Procalcitonin impacted antibiotic prescription during Foodborne illness.

DOES PROCALCITONIN IMPACT  ANTIBIOTIC PRESCRIPTION DURING FOOD BORNE ILLNESS


Khzouri TAKOUA, Fatnassi MERIEM, Ben Jazia AMIRA, Kehila OTHMEN, Aloui ASMA (Tunis, Tunisia), Fradj HANA, Brahmi NOZHA
08:30 - 17:40 #11013 - Door to needle time in STEMI – A quality indicator of Emergency Department.
Door to needle time in STEMI – A quality indicator of Emergency Department.

BACK GROUND

Providing quality and safe health care delivery is the cornerstone of all modern day health care system around the globe . Various international accreditation agencies has suggested different clinical / quality indicators as measure of quality health care management. Quality indicators are important for attaining and updating the knowledge of the health care providers as well  as for  the safe  management of the patients . Early reperfusion of ischemic myocardium either by thrombolysis or by percutaneous coronary angioplasty is the most important treatment modality to salvage ischemic myocardium .At Alkhor hospital thrombolysis was done in intensive care unit till December 2008 , from that period site of thrombolysis was shifted to Emergency Department  . From December 2008 onwards monitoring of door to needle time (DNT)was accepted as a quality indicator in emergency

AIM

 We sought to analyze the benefit of adhering to the quality indicator of  “door to needle time” in managing  patient presenting with Acute ST elevation myocardial infarction  and comparing it with international benchmark

METHODS

 A retrospective analysis of door to needle time was done at Alkhor hospital ,of patients who underwent thrombolysis for  STEMI at ICU and ED during the time period from April 2005 till the date.  DNT data during the period of April 2005 to December 2011 was analyzed before and found that DNT was reduced by 50 %.The median DNT was reduced from 33.5 minutes in the CCU to 17 minutes in the ED representing a reduction of more than 50% with a P value of < 0.0001 .Already Published 1

Door to Needle time is selected as a quality indicator of the department.DNT for all the patients admitted with STEMI is being recorded and monitored. Data from 2012 to 2016 is analyzed here and shows that the door to needle time average is  22 mts and is  maintained below 30 minutes which is the international quality bench mark .

Discussion:

The Displayed data clearly show that the Alkhor ED was able to provide treatment within the international bench mark of 30 mts. However 3 cases  (Fig 2 & 4) exceeded the time limit. These cases were followed up and the reason were evaluated.

Conclusion

By close monitoring and continues awareness of the healthcare providers the department is able to maintain  the time limit and provide quality care to the patient presenting with acute ST elevation Myocardial infarction

Quality can be achieved and maintained by continuous effort, team work and vigilant monitoring


Naseem AMBRA, Ann CHRISTINE, Nishan PURAYIL, Firjeeth PARAMABA, Vamanjore Aboobaker NAUSHAD (Qatar, Qatar), Sajid CHALIHADAN, Rosammal JOSEPH, Osama HASHIM
08:30 - 17:40 #10992 - Door to Needle Time in Stroke: intrahospital delays, predicting factors and improving strategies in the community hospital NOCSAE.
Door to Needle Time in Stroke: intrahospital delays, predicting factors and improving strategies in the community hospital NOCSAE.

Background: Stroke is a syndrome characterized by the sudden and rapid development of focal impairment of brain function with no other reason than that vascular, symptoms last longer than 24 hours or result in death, thus stroke is the third leading cause of death after myocardial infarction and cancer and the first of disability. The reflection is focused on the “Door needle Time” for the thrombolytic treatment, strictly dependent from a diagnostic-therapeutic path that must start from the pre-hospital with the awareness of the issue. The formulation of protocols has become necessary with absolute and relative criteria for inclusion and exclusion.  The place to start is the evidence that with adequate precautions and actions ictus is a foreseeable and curable condition. Aim: The aim of the study is to evaluate retrospectively which patients had better outcomes between  those treated with the former  and the latest  stroke protocols, comparing their respective Door to Needle Time (DNT). Methods:183 thrombolysed patients in 2015 have been stratified on cardiovascular risk, age, National Institute of Health Stroke Scale (NIHSS), primary or secondary centralization, the presence of early CT signs of ischemia, identification of exclusion criteria for thrombolysis, and management times (onset to door time –ODT; door to needle time -DNT; onset to needle time-ONT). Results: The patients analyzed were 84 women (45.9%) and 99 man (54.1%), the mean onset age was 72,8 years and the mean NIHSS was 9,8. The most frequent risk factors for stroke were hypertension (69.4%), dyslipidemia (45.3%), diabetes (16.9%), smoke (14.7%), atrial fibrillation history (23.5%) and previous stroke/TIA  (9.8%). 95 patients (52.8%) showed early TC signs. The median DNT was 61 minutes. The 56,7% of patients were treated in less than 60 minutes and this group had a better outcome at 3 month follow up. Conclusion: Improving stroke protocol we reduced DNT time passing from 48.6% patients with DNT


Andrea RIGHETTI (Modena, Italy), Marina BUDA, Francesca MORI, Serena SCARABOTTINI, Davide LUCCHESI, Valentina CAMERA, Brugioni LUCIO, Andrea ZINI, Geminiano BANDIERA, Niki AMADORI
08:30 - 17:40 #10875 - Dose-adjustable medications in the acute setting: a prescribing minefield.
Dose-adjustable medications in the acute setting: a prescribing minefield.

Medication prescribing in the acute setting is complicated by environmental distractors, simultaneous task execution, lack of clinical and demographic patient information and time pressures.

Several time critical medications indicated in the acute setting have narrow therapeutic windows and potentially toxic effects. These include antibiotics, anti-epileptics and bronchodilators. Prescriptions for such medications often require calculations which are complex and require knowledge of patient-specific parameters such as weight, age and renal function. This can cause delay in administration time and create margin for prescription error.

The concept of an electronic prescribing system is recognised as a major development in healthcare strategy. Electronic prescribing has spreading global popularity with increasingly appreciated capacity. There is proven efficacy in reducing error rate, cost and medication administration time, but its potential for improving accuracy of dosage calculations is less well reported.

Aim:  To audit accuracy of stat gentamicin dose prescription in acute medicine and accident and emergency departments of a large teaching hospital.

Method: This study examined single dose prescription of the aminoglycoside antibiotic gentamicin (indicated in the UK for sepsis of unknown source, severe hospital acquired pneumonia and gram negative bacteraemia) in the acute setting. 100 consecutive prescriptions of stat gentamicin were reviewed over a three-month period. We compared prescribed gentamicin dose with correct dose according to local hospital guidelines, based on creatinine, age and weight. Our findings were discussed in a forum to qualitatively investigate factors contributing to prescribing accuracy.

Results: At baseline, only 26.3% of prescriptions were accurate according to local guidelines. 21.0% of prescriptions had all necessary information available to the clinician at time of dose prescription. Contributing factors to poor prescribing accuracy included complexity of calculation, lack of time, an endemic practice of estimation rather than calculation to determine dose, and lack of awareness amongst prescribers of the local guidelines.

As a result of these findings, we involved hospital information technology and microbiology teams to develop an electronic prompt and dose calculator on the hospital electronic prescribing system.

We conclude that accuracy of dose adjustable medication prescribing can be inadequate in the acute setting because of environmental factors, complexity of calculations and unavailability of relevant patient parameters to the clinician at time of prescription. Prescribers are not accurate in estimating doses. Electronic prescribing systems present an exciting option to address these issues, enabling introduction of prompts and electronic calculators. Our work has implications across emergency department settings for improving prescribing safety, speed of administration, and overall patient outcome.


Dr Bronwen E WARNER (London, United Kingdom), Elizabeth PARSONS, D John M REYNOLDS
08:30 - 17:40 #11161 - DRESS (drug reaction with eosinophilia and systemic symptom) syndrome: a case report.
DRESS (drug reaction with eosinophilia and systemic symptom) syndrome: a case report.

Introduction:

The Drug Reaction with Eosinophilia and Systemic Symptom (DRESS) is a rare and serious drug toxidermia. Due to the frequent multi-organ involvement, this condition can be associated with a severe prognosis. Many treatments are incriminated. The most frequently reported are the antiepileptic agents (phenobarbital, carbamazepine, phenytoin, lamotrigine).

 

Case Report:

A 70-year-old male was admitted to the emergency department (ED). He had a history of high blood pressure, pulmonary embolism, and two months earlier, he had been diagnosed with a brain tumor for which he was taking carbamazepine, phenobarbital and corticosteroids. The corticosteroids had been stopped two weeks before to the admission and since then the patient had developed a fever and generalized maculopapular eruptions with itching.

Physical examination revealed a widespread maculopapular rash all over the body (even palms and foot soles) with exfoliation and a significant facial oedema. Furthermore, he had a stable general condition. Laboratory tests showed hyperleukocytosis (14900/mm3) with hyperoeosinophilia (3635/mm3 (24%), no deterioration of hepatic or renal function. The diagnosis of DRESS syndrome was made. The suspected causative drugs: Carbamazepine and Phenobarbital were withdrawn and systemic corticosteroids (1mg /kg/day) were initiated. The patient has been admitted to the internal medicine department.  A pharmacovigilance test occurred had concluded that DRESS syndrome is highly suspected and it is mostly caused by aromatic anticonvulsants (carbamazepine and phenobarbital). The skin biopsy confirmed the diagnosis. The Systemic corticosteroids were maintained. The outcome was favorable with clinical and biological amelioration.

Conclusion:

DRESS syndrome is a serious drug reaction with high mortality due to systemic involvement. Rapid diagnosis is crucial as prompt withdrawal of the offending drug is the key of the treatment. Delaying this measure is associated with a poorer prognosis. 


Hanen GHAZALI (Ben Arous, Tunisia), Rihab DIMASSI, Siwar JERBI, Anware YAHMADI, Najla ELHENI, Sawsen CHIBOUB, Mohamed MGUIDICH, Sami SOUISSI
08:30 - 17:40 #10944 - Drug Reaction with Eosinophilia and Systemic Symthoms ( Sd DRESS).
Drug Reaction with Eosinophilia and Systemic Symthoms ( Sd DRESS).

Cutaneous Rash and deterioration of the general state.

 

PERSONAL PRECEDENTS:

 

- Not allergies medicamentosas well-known

- Exsmoker from year 2000. I do not consume ethanol.

- Social and basal situation: native of China, region close to Shanghái It is employed at a clothes shop. Independent for ABVD

 

- Treatment before to revenue: Alopurinol 300mg 1-0-0  Colchicina 1mg c/24h (, Betahistina 8mg 1-1-1 , Dexclorfeniramina 2mg 1-1-1 Amlodipino 5mg 0-0-1, Fluticasona furoato 55mcg nasal, Terbinafina local application.

PATHOLOGICAL PRECEDENTS:

 

- Arterial hypertension diagnosed in 2015. Good control with 1 medicine.

- Recent hiperuricemia diagnosis with gouty crisis

- Already well-known renal Litiasis

CURRENT ILLNESS:

 

53-year-old male comes to Urgencies for picture of 3 days of evolution of rash, asthenia, hiporexia and sickness, fever 39ºC with progressive increase of the rash, of beginning in abdomen up to spreading of widespread form. Not pruriginoso.

Valued previously for primary health care, it was prescribed betahistina and dexklorfeniramina without improvement.

General: NH. General good condition. Predominance Eritema maculopapuloso in abdomen and thighs, confluent up to forming badges.

NRL: PICNR. MOEs consevados. Not signs annoyance meníngea.

Cardiocirculatory: RCR, did not auscultate blows.

Respiratory: good bilateral ventilation

Abdomen: globuloso, normal RHA

EEII: without edemas or signs TVP.

 

COMPLEMENTARY TESTS:

 

 AG : 14200leucocitos/uL (N. absolultos 8150, L. absolute 3870, E. absolute 560), red blood corpuscles 5,51, Hb 15,70, Ht 47,50 %, 124000plaquetas/uL, INR 1,35, Glucose 129, urea 64, Creat 1,90, entire Bil 4,7 (direct 3,8), ALT 790, GGT 239, Na 135, K+3m6, CPK 193,

Pathological anatomy, biopsy skin :

"vasculitis linfocítica"

The changes are compatible with the clinical diagnosis of suspicion (syndrome DRESS)

 

EVOLUTION:

It is faced initially like possible Syndrome DRESS (Drug Reaction with Eosinophilia and Systemic Symthoms) for alopurinol, initiating treatment corticoideo systemic during its stay in UCI.

There has been realized early detection of other causes of hepatic and renal defeat, discarding of reasonable form the possibility of autoimmune hepatitis, poisonous hepatitis and linfoma cutaneous. Nevertheless, 2 presents a beta determination high microglobulin, without component monoclonal quantifiable.

It has presented good evolution, with clinical and analytical improvement. The facial edema has disappeared and the rash has been mitigated. The initial eosinofilia has normalized, objetivando also important descent of the parameters of colestasis and citolisis.

 


German Jose FERMIN GAMERO (PALMA DE MALLORCAQ, Spain), Elena ALFARO GARCIA-BELENGUER, Julio OLSEN, Claudina REVOL, Lara PUERTO, Bernardino COMAS DIAZ
08:30 - 17:40 #11882 - Early detection of hyperkaliemia in patients with chronic renal failure in ED.
Early detection of hyperkaliemia in patients with chronic renal failure in ED.

Background: The number of patients suffering from chronic renal failure increased steadily. These patients consult frequently to emergency department (ED) for different complaints. However, hyperkaliemia is the most frequent and serious disorder. The aim of our study is to define the correlation between ECG and serum levels of kaliemia.

Patients and methods: This prospective study included all patients with chronic renal failure who presented to the ED of a teaching hospital from January 2016 to June 2016 with various complaints. Clinical and biological are defined. We determined who have hyperkalimia in biological test. We studied clinical signs and ECG signs at admission for all patients presented to the emergency department and we define the correlation between ECG signs and potassium serum level .

 Results: Sixty nine patients are collected. Mean age was 67 years old, 64 % are men and 36% are women. Hypertension and Diabetes mellitus were the most associated diseases, 52% and 56 % respectively. The most frequent complaints are dyspnea in 29 % and asthenia was found in 20 % of patients. Mean creatinine clearance was 856 umol/ml, mean serum potassium level was 5,3 mmol/l. Nine patients has hyperkaliemia and ECG abnormality. The ROC curve permitted to determine a distinguishing threshold at 6,5 mmol. At this level, the positive predictive value is 79 % and the negative predictive value is 45 %.

Conclusion: Hyperkalemia can be a life-threatening disorder. ECG is an interesting tool for an early detection of hyperkaliemia in patients with chronic renal failure but normal ECG does not rule out this metabolic disorder. Blood analysis should be performed in patients with chronic renal failure at high risk to develop hyperkaliemia.


Houda NASRI (CHARTRES), Faten AMIRA, Rim HAMAMI, Imen MEKKI, Chokri HAMOUDA
08:30 - 17:40 #11980 - Early discharge and long term outcome in traumatic intracranial hemorrhage.
Early discharge and long term outcome in traumatic intracranial hemorrhage.

Introduction: Head trauma is associated with high morbidity and mortality. Common complications of head trauma are intracranial hemorrhages (ICH), which may cause numerous physical and cognitive disabilities. This study was performed to evaluate the association between early discharge and long-term outcome of patients with traumatic ICH.

Materials & Methods: In this prospective cohort study, patients with traumatic ICH referred to emergency departments (EDs) of Firoozgar and Shohadaye Haft-e Tir in Tehran in 2015 were investigated. Demographic and clinical characteristics of the patients were recorded in the check list and then radiologic assessment was done. According to time of discharge, the patients were divided into two groups: early discharge (≤ 24 hours) and late discharge (> 24 hours). All subjects were followed by intervals of 24 hours, one month and three months after discharge and their outcome were evaluated based on clinical criteria and the Glasgow Outcome Scale (GOS). The collected data were analyzed using SPSS-24.

Results: A total of 28 patients (84.8%) in the early discharge group and 36 patients (81.8%) in the late discharge group completed the study. The age distribution was similar between two groups. In the first group, 26 patients (92.8%) and in the second group, 25 patients (69.4%) were male. Epidural hemorrhage was the most common type of intracranial hemorrhage (n = 15, 53.7% vs. n = 27, 75.0%; P = 0.005). The most common clinical symptoms after discharge were headache in the first group and headache and vertigo simultaneously in the second group (n = 7, 25.0% vs. n = 4, 11.1%; P = 0.020). At the end of follow-up, in the first group of 28 patients (100%) had GOS = 5 and in the second group, 33 patients (91.7%) had GOS = 5 and 3 patients (8.3%) had GOS = 4 that were statistically not significant (P = 0.118).

Conclusions: The results of this study showed that early discharge of patients with traumatic ICH had fairly similar outcome with patients with late discharge.


Dr Reza MOSADDEGH (Tehran, Islamic Republic of Iran), Mahdi REZAI, Saeid MOLLAEI
08:30 - 17:40 #11447 - Early unplanned hospital readmission within seven days after emergency department discharge: who, why and how.
Early unplanned hospital readmission within seven days after emergency department discharge: who, why and how.

Introduction: Previous research studied early hospital readmissions after discharge of emergency patients, with the aim to quantify them, to assess the quality of health care service, and to identify risk factors. Readmission rate varies between 2 and 5 %, and it would be 3% within 72 hours in the United States, and 2 % within 8 days in France. Furthermore, the readmissions curve according to the deadline of these would be of inverted exponential type and would become linear from the ninth day, suggesting a link with the first emergency department (ED) admission, and it would be more frequent until this deadline. It was demonstrated that old age as well as some comorbidities (history of cancer, chronic cardiopulmonary disease) are associated to a bigger risk of readmission. Patients and Methods: Retrospective study of all patients admitted in the ED between January and June 2015, and which had a home discharge followed within 7 days by an ED readmission or by a direct hospitalization in another service. The purposes of this study were to (1) quantify diagnostic and prognostic errors; (2) evaluate patients whom we called of very unfavorable outcome (VUO; patients admitted in the shock room, in ICU or CCU during their hospital return), as well as their hospital mortality. Results: A total of 1171 patients were included. The hospital readmission rate was 4.48 % at 7 days (2.87 % at 72 hours). Diagnostic error, prognostic error and VUO patient rates were 12.9 %, 15.5 %, and 6 %, respectively. The hospital mortality rate was 1.6 %. Infectious diseases represented about one-third of diagnostic errors and almost one-quarter of VUO patients. A secondary analysis of these infections found that 40 patients were readmitted with an identified source of serious infection and\or with sepsis. Conclusion: Prevention of hospital readmissions remain challenging for emergency physicians. In this study, serious infectious diseases were 4 times and two times more involved in a diagnostic error event and in VUO patients respectively, than all gathered cardio-neurological diseases. And in general, the first ED admission occurred during the early phase of these infections. A better detection of the source in deemed infected patients, as well as a follow-up visit of the family doctor within 72 hours after home discharge could contribute to reducing the rate of early hospital returns.


Martin BEHR, Eleonore SEUVIC, Manana POTOCNIK, Pepijn GERBER, Ruxandra COJOCARU, Fadi KHALIL, Pascal BILBAULT, Paul GAYOL (Strasbourg)
08:30 - 17:40 #11789 - Early Whole-Body Computed Tomography during post-resuscitation care in out-of-hospital cardiac arrest.
Early Whole-Body Computed Tomography during post-resuscitation care in out-of-hospital cardiac arrest.

Background:

Whole-Body Computed Tomography (WBCT) as well as Percutaneous Coronary Intervention (PCI) are procedures recommended by current guidelines during post-resuscitation care in the emergency department. Nevertheless the relevance of WBCT to detect both causes and complications of out-of-hospital cardiac arrest (OHCA) is still unclear. We evaluated the routine use of early WBCT before PCI in a single university cardiac arrest center.

Methods:

Patients admitted to our university cardiac arrest center following OHCA underwent WBCT using a defined post-cardiac-arrest-protocol immediately after admission to the resuscitation room and before indication of PCI or other emergency procedures. The results of WBCT were included in further emergency treatment decision making. We evaluated the results of WBCT in unconscious patients admitted after out-of-hospital cardiac arrest during the period of 1.1.2016-30.09.2016.

Results:

Routine WBCT of n=72 patients could be included. The following list shows relevant acute pathological findings in their number and frequency:

  • Intracranial haemorrhage; N=2 (2,8%)
  • Pulmonary embolism; N=8 (11,1%)
  • Cardiac tamponade; N=3 (4,2%)
  • Thoracic aortic dissection/rupture; N=1 (1,4%)
  • Abdominal aortic dissection/rupture; N=2 (2,8%)
  • Signs of aspiration; N=30 (41,7%)
  • Pneumothorax left or right; N=9 (12,5%)
  • Pneumothorax bilateral; N=3 (4,2%)
  • Series of rib fractures; N=37 (51,4%)
  • Abdominal haemorrhage; N=2 (2,8%)

Discussion:

The routine use of early WBCT in unconscious patients following OHCA showed both causes and complications of cardiac arrest. These findings can be of vital importance for the initial emergency treatment. Further large scale studies should be performed to verify these findings.


Susanne BETZ, Stefanie PEKRUHL, Birgit PLOEGER, Martin SASSEN, Barbara CARL, Konstantin KARATOLIOS, Birgit MARKUS, Bernhard SCHIEFFER, Clemens KILL (Essen, Germany), Andreas MAHNKEN, Jens Holger FIGIEL
08:30 - 17:40 #11287 - ECLS in severe accidental hypothermia: Decision-making in low incidence, high relevance situations.
ECLS in severe accidental hypothermia: Decision-making in low incidence, high relevance situations.

Severe accidental hypothermia (AHT) is a rare disease, but survival of hypothermic patients with cardiovascular instability or even cardiac arrest highly depends on detecting the underlying disease and having a clear and robust decision-making for further treatment. In recent years, advances in extracorporeal life support ECLS increased the chance of survival of out-of-hospital cardiac arrest OHCA. This includes the development of chest compression systems, the use of ECMO (extracorporeal membrane oxygenation) or the advancement of the classic ECC (extracorporeal circulation), As all these advanced systems are personnel-intensive and expensive, selection of the right patients is of utmost importance.

The 2015 ERC guidelines provide very clear recommendations on the assessment and therapy of patients suffering from accidental hypothermia. The diagnosis of accidental hypothermia can either be made based on clinical sings and symptoms - usually the method for out-of hospital care - or the measurement of core temperature, which usually is performed in-hospital. Treatment options include forced warm air, central-venous catheters for intravenous rewarming or ECLS strategies, which usually require transfer to a specialized center.

In order to select patients who profit from these advanced therapies, ambulance services and air rescue teams must know signs and symptoms of the different stages of AHT. Emergency departments must be able to detect hypothermia and should have at least one reliable method for measuring core temperature. All emergency teams must have a specialized algorithm for the diagnosis and therapy of AHT and must maintain their competence in AHT with regular training. This does not only improve adherence to the algorithms but moreover sensitizes the teams to the clinical picture of AHT. Avalanche accidents are a special situation where accidental hypothermia can improve the chances for survival. These patients represent a minority of the avalanche victims, but if correctly selected and intensively treated, they have a high chance of survival and excellent outcome - even in OHCA situations.

Existing algorithms like the Avalanche Checklist or the Bernese Hypothermia Algorithm for hypothermic patients in cardiac arrest must periodically be updated and optimally should adhere to evidence-based recommendations. Because of the rarity of the disease and the impossibility of conducting good prospective research, registries are promising instruments to reach a higher level of evidence.  The already existing International Hypothermia Registry, the new International Alpine Trauma Registry and the upcoming International Avalanche Registry are not only able to collect information about hypothermic patients from the incidence site and in-hospital care and outcome, but  in the future, they will provide essential data for high-quality recommendations on best quality of care for patients suffering from severe accidental hypothermia.


Dr Monika BRODMANN MAEDER (Bern, Switzerland), Balthasar EBERLE, Hermann BRUGGER, Aristomenis EXADAKTYLOS
08:30 - 17:40 #11592 - Effect of chronic kidney disease on NSTEMI acute coronary syndrome.
Effect of chronic kidney disease on NSTEMI acute coronary syndrome.

Background: Chronic kidney disease (CKD) is highly prevalent worldwide and is associated with an increased risk for adverse outcomes in patients hospitalized with acute coronary syndrome (ACS).

Methods:  A prospective observational study conducted in emergency department from July 2015 to April 2017. Patients aged more than 18 years, with NSTEMI are included. Patients were categorized into 2 groups on the basis of hospital admission creatinine clearance (CrCL) calculated by MDRD (2): G1 (CrCL   ≥ 60ml/min); G2 (CrCL < 60ml/min).

Results: One hundred sixty eight patients were included. Among these we individualized 121 with normal function and 47 with renal dysfunction. Patients with baseline renal dysfunction were older (67 years VS 58 years, p < 0,001), and more likely to have prior comorbidities (%): hypertension (44% G1 vs 79 % G2; p < 0,001), Diabetes (G1 34%  vs 64%G2 ; p < 0,001); Coronary artery disease ( G1 25% vs G2 45%; p = 0,013). The 30-day mortality was higher for patients with renal dysfunction compared with patients without renal dysfunction but it is not statically significant. (G1 3, 3 % vs G2 10, 63%; p= 0,058).

Discussion:  the correlation between kidney and heart disease has been explored, and it was shown that the interaction between the kidney and the heart increases the burden for both organs if one becomes diseased. The main limitations of this study  was that GFR at admission was calculated by MDRD, It would be interesting to study CKD with other or a new equation (CKD-EPI creatinine equation)  wich is considered more accurate than MDRD.

 


 


Maroua MABROUK, Hana HEDHLI, Sarra JOUINI, Badra BAHRI, Alaa ZAMMITI (Tunis, Tunisia), Hela BEN TURKIA, Abir WAHABI, Chokri HAMOUDA
08:30 - 17:40 #9947 - Effect of ischemia preconditioning on PDGF-BB expression in the gerbil hippocampal CA1 area after transient cerebral ischemia.
Effect of ischemia preconditioning on PDGF-BB expression in the gerbil hippocampal CA1 area after transient cerebral ischemia.

 

Purpose: Ischemia preconditioning (IPC) induced by briefing the duration of transient ischemia represents ischemic tolerance to a subsequent longer or lethal ischemia. In the present study, we examined effects of IPC (2 min of transient cerebral ischemia) on immunoreactivity of platelet derived growth factor (PDGF)-BB as well as neuroprotection in the gerbil hippocampal CA1 area after a lethal transient cerebral ischemia (LTCI; 5 min of transient cerebral ischemia).

Methods: Animals were divided into four groups (n = 7 at each point in time in each group): (1) sham-operated group were exposed the bilateral common carotid arteries and no ischemia was given (sham-operation); (2) ischemia-operated group were given a 5 min of transient cerebral ischemia (lethal transient cerebral ischemia, LTCI); (3) IPC plus sham-operated group (IPC+sham-operated group) were subjected to IPC prior to sham-operation; and (4) IPC+ischemia-operated group were subjected to IPC prior to LTCI. The IPC paradigm has been proven to be very effective at protecting neurons against ischemic damage in this ischemic model (24). The animals in groups (2) and (4) were given recovery times of 1 day, 2 days and 5 days, because pyramidal neurons in the hippocampal CA1 region survive until 3 days and begin to die 4 – 5 days after LTCI.

Results: LTCI induced a significant loss of pyramidal neurons in the hippocampal CA1 area 5 days after LTCI and significantly decreased PDGF-BB immunoreactivity in the CA1 pyramidal neurons from 1 day after TLCI. IPC effectively protected the CA1 pyramidal neurons from LTCI and increased immunoreactivities of PDGF-BB in the CA1 pyramidal neurons after LTCI.

Conclusion: In brief, our results show that a TLCI significantly changed PDGF-BB immunoreactivity in pyramidal neurons in the hippocampal CA1 area and that IPC increased the immunoreactivity. These findings indicate that PDGF-BB is related with IPC-mediated neuroprotection.


Jun Hwi CHO, Taek Geun OHK (Chuncheon, Republic of Korea), Chan Woo PARK, Joong Bum MOON, Myoung Chul SHIN, Moo Ho WON
08:30 - 17:40 #11319 - Effect of mobile learning core muscles activation for the increase of quality in cardiopulmonary resuscitation.
Effect of mobile learning core muscles activation for the increase of quality in cardiopulmonary resuscitation.

Objectives:

This study aimed to determine whether mobile-learning core muscle activation (CMA) increase cardiopulmonary resuscitation (CPR) quality in female registered nurses.

 

Method:

We performed prospective single-blinded randomized study. 66 registered nurses were randomly allocated to the intervention (n = 34) and control groups (n = 32). After the muscle powers of the participants were measured, chest compressions were performed on manikins for 4 min continuously according to the control of metronome sound (110 beat per minute).  During chest compressions, the CPR quality, elbow angle and muscle fatigue of participants were measured simultaneously. After mobile learning CMA was applied to the intervention group for 5 weeks, the CPR qualities for the two groups were reevaluated. Primary outcome was the proportion of complete chest compressions (5-6 cm chest compression depth and ≤ 1cm of residual leaning). Secondary outcomes were muscle power, elbow angle and muscle fatigue.

 

Results:

The proportion of complete chest compressions in the intervention group (3.2 % to 22.5 %) significantly increased comparing with control group (1.8 % to 11.8 %) after CMA (p = 0.045). There was no significant increase of core muscle power in the intervention group comparing with the control group (p = 0.059). However, the total muscle power in the intervention group significantly increased comparing with control group (p = 0.001). The change of elbow angle during chest compressions did not differ between the two groups after CMA (p = 0.473).

 

Conclusions:

Mobile core muscle activation could provide assistance to the increase of the proportion of complete chest compressions and muscle power for female registered nurses, and this can be easily performed anywhere.  


Wonhee KIM (Seoul, Republic of Korea), In Young KIM, Shinil KANG, Seungjae LEE, Gu Hyun KANG, Yong Soo JANG, Hyun Young CHOI, Jae Guk KIM, Minji KIM
08:30 - 17:40 #10912 - Effect of on educational intervention on emergency nurses competence.
Effect of on educational intervention on emergency nurses competence.

Emergency nurses require unique knowledge and skills to provide care to the complex and variable population of emergency department patients. In Finland nursing education includes three years of applied science studies (210 ECTS) that leads to the degree Bachelor of Science in Nursing and enables graduates to work as general registered nurses (RN). Current undergraduate nursing education does not provide sufficient knowledge or skills to enable emergency nursing competence. However, no formal postgraduate education for emergency nurses exists in Finland. According to Finnish legislation, all RNs are competent to meet patients’ safety and care needs and provide evidence-based,high quality nursing care.

An educational intervention was developed by HUH Emergency Medicine and Services in collaboration with Arcada University of applied sciences. The main objectives of the intervention were to improve emergency nurses’ basic and specialist competencies and to improve EBP in emergency nursing. The content of the intervention was developed by a panel of multi-professional experts working in ED setting, which was then focused on the theoretical categories of the Nurse Competence Scale (NCS, Meretoja 2003). The intervention was a multifaceted education initiative comprising theoretical lectures, simulation, workshops and work-rotation. Instructors were ED medical staff.

The purpose of this study was to describe effect of the educational intervention on emergency nurses’ self-assessed level of competence (N=19). Data was collected 10 days before and after the intervention by using the NCS instrument. Competencies are assessed by using Visual Analogue Scale (VAS 0-100). VAS-points from 0–25 indicate low level, points >25–50 rather good level, points >50–75 good level and points >75–100 very good level of competence.

The main result was that educational intervention in emergency nursing improved the nurses’ self-assessed overall level of competence (VAS mean 58.8 vs 73.1). The biggest positive chance was in “Ensuring Quality” category (VAS mean 45.4 vs 71.0). Chances in other competency categories were as follows: Therapeutic interventions (VAS mean 52.1 vs 68.9); Work role (VAS mean 58.5 vs 72.9); Helping role (VAS mean 64.2 vs 77.5); Managing situations (VAS mean 62.7 vs 75.7); Teaching–coaching (VAS mean 58.5 vs 70.2), and Diagnostic functions (VAS mean 66.2 vs 75.6). Even though the intervention focused on improving nurses clinical skills, there were great improvements in quality development and evidence based nursing skills. The results suggest that the intervention has promise to improve emergency nurses’ competence. Results will be used to promote questions related to research, development and continuous education in emergency nursing to improve emergency nurses’ competence. Further research is recommended to evaluate the teaching methods and content that are most effective in increasing emergency nurses’ professional competence and work performance.


Elina KOOTA, Hilkka KIVELÄ, Marja RENHOLM, Riitta MERETOJA, Elina KOOTA (Helsinki, Finland)
08:30 - 17:40 #11118 - Effects of intravenous administration of fentanyl and lidocaine on hemodynamic responses following endotracheal intubation.
Effects of intravenous administration of fentanyl and lidocaine on hemodynamic responses following endotracheal intubation.

Background and Objectives: Endotracheal intubation is associated with hemodynamic changes such as tachycardia and hypertension. Many drugs can be used prior to intratracheal intubation to blunt such harmful responses, including numbing agents, antiarrhythmic drugs (including lidocaine), vasodilator agents repressing sympathoadrenal response (barbiturates like thiopental and methohexital), α- and ß-adrenergic blockers (esmolol), opioids (such as fentanyl and remifentanyl) and calcium channel blockers. The aim of the present study is to compare the effects of fentanyl and lidocaine in patients who require Rapid Sequence Intubation (RSI) in the emergency department (ED).

Subjects and Methods: We conducted a prospective, simple nonrandomized, double-blind clinical trial in 96 patients who needed emergency oropharyngeal intubation. The patients were randomly divided into three groups (fentanyl group, lidocaine group, and fentanyl plus lidocaine as our control group). The control group (M) was administered with 3µgr/kg intravenous (IV) fentanyl and 1.5µgr/kgIV lidocaine, fentanyl group (F) was injected with 3µgr/kg IV fentanyl and lidocaine group (L) received 1.5mg/kg IV lidocaine prior to endotracheal intubation. Heart rate (HR) and mean arterial pressure (MAP) were assessed4 times: before intubation, exactly after intubation, 5 and 10 minutes after intubation with the chi-square test. 

Results: HR was notably different in F, L and M groups during four time courses (p<0.05).Comparison of MAP at measured pointsin all groups exhibited no significant association(p>0.05). In fentanyl group both HR and MAP increased immediately after intubation and significantly decreased 10 minutes after intubation (p<0.05).

Conclusions: Overall,the result of this study showed that lidocaine effectively prevents MAP and HR fluctuations following endotracheal intubation.According to our findings, lidocaine or an admixture of fentanyl and lidocaine are able to diminish hemodynamic changes and maintain the baseline conditions of the patient would, thus act more effective than fentanyl alone.


Mohammad Davood SHARIFI (Mashhad, Islamic Republic of Iran), Raheleh FARAMARZI, Maziar SAADATFAR, Hamideh FEIZ
08:30 - 17:40 #11727 - Electrical cardioversion (ECV) in emergency department: evolution of the procedure used in atrial fibrillation patients, analysis of 12 years’ practice.
Electrical cardioversion (ECV) in emergency department: evolution of the procedure used in atrial fibrillation patients, analysis of 12 years’ practice.

1) Introduction and aims:

We aim to analyse the development of the electrical cardioversion use in patients presenting atrial fibrillation (AF) at the emergency department during the period 2003 – 2014, since the implementation of the atrial fibrillation clinical practice guidelines in 2003.

2). Material and methods:

This is a prospective, observational study, including a consecutive series of patients attended to at an emergency department with the diagnosis of atrial fibrillation from January 1, 2003 to December 31, 2014.  Patients remained at the observation unit for treatment and monitoring. Data were obtained from the patient’s computerized medical history and filed in a database (FileMaker Pro 12).

3) Results:

ECV was conducted in 195 patients during the study period: 2 patients in the year 2003 (AF guidance set – up); 6 in 2004 and 2005; 11 in 2006; 16 in 2007; data loss between 2008 – 2010; 30 in 2011; 28 in 2012; 48 in 2013 and 48 in 2014. There was no case of death or severe complications. Sinus rhythm (SR) was restored in 185 patients (94.8%), adverse events were reported in only 1.3 per cent of the patients who underwent ECV; the average stay was 10.4 hours concluding with a 99.8% hospital discharge. We conclude that the profile of a patient with indications for a successful ECV is 52 year – old men presenting episode of AF, with CHA2DS2 score of 0.81 and HAS-BLED score of 0.56, on average.

4). Conclusions:

1. Electrical cardioversion is a safe method for the treatment of atrial fibrillation. Its increased use when clinical indications are met, concluded with successful cardioversion in 95 per cent of the patients. Low rate of adverse effects (<2%) also supports its use and recommendation.

2. ECV effectiveness has lead to a substantial evolution of this procedure; outcomes registered point to a progressive increase in its use at the emergency departments that means a highlight in the quality process of AF management in these services.


Isabel PÉREZ PAÑART, Victoria ORTIZ BESCÓS (Zaragoza, Spain), Marta DEL PUEYO PARRA, Román ROYO HERNÁNDEZ, Teresa ESCOLAR MARTÍNEZ DE BERGANZA, Patricia ALBA ESTEBAN
08:30 - 17:40 #11951 - EMERGENCY DEPARTMENT EPIDEMIOLOGY AND MANAGEMENT OF CARDIAC RHYTHM TROUBLE.
EMERGENCY DEPARTMENT EPIDEMIOLOGY AND MANAGEMENT OF CARDIAC RHYTHM TROUBLE.

INTRODUCTION:

Rhythm trouble are frequently associated with life threatening conditions such as acute heart failure and dizziness. The aim of our study was to determine epidemiological and outcome characteristic of patients with rhythm trouble managed in the emergency department.

METHODS:

Our retrospective study included 106 patients with cardiac rhythm trouble, diagnosed at the emergency department, from march 2016 to march2017.

RESULTS:

Median age was 66.55 years (22 to 91 years). Males represented 43 % of the patients (45/106). 33 % of patients were smokers. The medical history indicated that 68 % of patients had hypertension and 23.9 % had coronary heart disease. Furthermore, 45 % of patients already had a cardiac rhythm disorder.

The most widely used antiarrhythmic are: beta blockers in up to 32.65 % of patients, and calcium channel blockers in 12.8 %. Sixty three point three of patients were receiving anticoagulants. The reason for consultation was: dyspnea in 51.5 %, palpitation in 33 % and asthenia in 32.5 % of total cases.The most frequently cardiac rhythm trouble was atrial fibrillation (70.6 %). Patients not receiving anticoagulants died more often (p<0.05). A positive development was noticed in 85.5 % of cases. The average period of treatment was 2.28 days (between less than 24 hours and 11 days). Only 18.3 % of patients were transferred to cardiology department.

CONCLUSION:

More efforts and cooperation between cardiologists and emergency physicians to improve the management of rhythm trouble by shortening their stay in emergency department and ensuring a better long term control of that desease in order to reduce emergency visits.


Sana LAHMAR, Wiem DEMNI (Chartres), Ines BELGACEM, Ahmed GUESMI, Fatma MEJRI, Nour El Houda NOUIRA, El Moez BEN OTHMANE, Maamoun BEN CHEIKH
08:30 - 17:40 #11664 - Emergency department pain management in pediatric patients with long bone fracture.
Emergency department pain management in pediatric patients with long bone fracture.

Emergency Department Pain Management in Pediatric patients with long bone Fracture.

 

Objective: Pediatric patients may be unable to express their pain in the emergency department.

We aim to select the factor if there are differences in pain management of acute long bone fracture among age groups especially in pediatrics who have visited the Emergency Department.

 

Method: We retrospectively reviewed charts of patients presenting to the EDs with acute

long bone fracture from January 2013 to December 2014. A totalof 412 patients were enrolled, and sex, age, arrival method, arrival time, injury mechanism, fracture location, fracture type, times to initial pain medication,the time of physician primarycareand disposition were analyzed.

 

Results: Pain medications were given to 79.1% of all patients with acute long bone fracture presenting to the ED.  But 52.3% of pediatric patients (0-18years) and 68.7% of geriatric patients (above 65years)(p<0.01) administrated pain medications.The analysis of the time to pain medication administrations of pediatric patients were significant delay.

 

Conclusion:  The Pediatric patients who presented to the ED for acute long bone fracture were less likely than older age patients to receive pain medications and waited longer for their pain management.   


Kiho SEO (SEOUL, Republic of Korea)
08:30 - 17:40 #10908 - Emergency department registered nurses’ competencies in disaster medicine. A Delphi study.
Emergency department registered nurses’ competencies in disaster medicine. A Delphi study.

Introduction: Being among the first line of health care providers to receive, assess and treat victims from a major incident or disaster, registered nurses at emergency departments play vital roles in the initial management of disaster victims.  The disaster medicine competencies they possess are essential for mitigating both mortality and morbidity during a disaster or major incident.

 

Problem: Despite regulations requiring evaluation of nurses’ disaster preparedness, the level of disaster preparedness among nurses at the emergency department in Stockholm, Sweden is not known. In addition, a national disaster medicine-specific competency description is absent, resulting in a lack of recognized tool for assessing emergency department nurses’ disaster preparedness. The aim of this study was to identify disaster medicine competencies for emergency department registered nurses.

 

Methods: A three round modified Delphi- method was utilized for identifying disaster medicine competencies. A group consisting of international and national experts within emergency and or disaster medicine participated (n=40) with 33 completing all 3 rounds. Forty-five competencies were identified in the previously validated disaster preparedness questionnaire. The contents of this questionnaire were then modified and expanded to 59 statements prior to the first round. Experts then rated each statement using a five point Likert scale and were encouraged to leave comments and suggest new statements. Statements that reached the predefined consensus level of 75% were considered essential disaster medicine competencies for emergency department registered nurses.

 

Results: An expert group consisting of 33 national and international experts identified 69 specific competencies for emergency department registered nurses’ disaster preparedness. Competencies with the highest rate of consensus concerned daily emergency care such as basic first aid, as well as statements relating to rare events such as decontamination.  

 

Conclusion: Essential disaster medicine competencies for emergency department RNs were identified using a modified Delphi method. These competencies may provide the basis of a tool for assessing the disaster preparedness of registered nurses working in emergency department. 

 


Jason MURPHY (Stockholm, Sweden), Monica RÅDESTAD, Lisa KURLAND, Maria JIRWE, Ahmadreza DJALALI, Anders RÜTER
08:30 - 17:40 #11015 - Emergency Department utilisation be patients with low urgency according to Manchester Triage System category: diagnoses, in-hospital course and long-term mortality.
Emergency Department utilisation be patients with low urgency according to Manchester Triage System category: diagnoses, in-hospital course and long-term mortality.

Background

EDs worldwide are facing increasing patient numbers. Especially ED utilization of low-acuity patients seems to increase and health care structures need to be adapted to prevent overcrowding and ensure high-quality patient care.
Some concepts suggested to redirect low-acuity patients from EDs to primary health care structures but instruments to identify such patients are still lacking.
We investigated diagnoses, in-hospital course and long-term mortality of patients with low urgency according to Manchester Triage System (MTS) to evaluate whether these patients could be redirected to primary health care structures.

Objectives
Description of Diagnoses, in-hospital course and 1-year mortality patients with non-urgent MTS triage categories.

Methods
Data of 1,152 adult, non-surgical patients who presented to the ED of a tertiary care hospital between Dec 2010 and Nov 2011 were analyzed. Data on patient characteristics, ED triage, ED and in-hospital diagnoses and in-hospital course were extracted from the hospital information system. Mortality after one year was assessed in the German register of residents. A non-urgent triage category was defined as a green or blue triage category. Diagnoses were analyzed as 3-digit ICD-10 codes.

Results
Of all 1,152 patients, 52.1% were male (n=600) and 47.9% female (n=552). Patients had a median age of 59 years (IQR: 43-71). 1 year mortality was 9.8% (n=102). Vital status was missing in 9.3% of all patients (n=107). Of all patients with inital triage assessment (n=1,122), 30.4% (n=341) had a green triage category and 1.5% (n=17) a blue triage category. Of these non-urgent patients, 52.0% (n=186) were female and 48.0% (n=172) male. Their median age was 56 years (IQR: 35-71). Clinical data are presented in table 1. The 1-year mortality of these patients with non-urgent triage categories was 7.9% (n=26).

Conclusions
A high proportion of patients who require inpatient treatment with severe diagnoses in patients with non-urgent triage categories demonstrates that these patients could not have been redirected to primary care services. Moreover this finding is supported by a high 1-year mortality in these patients.

Inpatients course of patients with green and blue MTS category (n=358)


inpatient treatment 29.6% (106)
ICU treatment 2.8% (10)
in-hospital mortality 0.8% (3)


Top 5 diagnoses in the ED (n=358)
gastroenteritis/colitis (A09) 7.0% (25)
dizziness and giddiness (R42) 3.1% (11)
primary hypertension (I10) 3.1% (11)
angina pectoris (I20) 2.8% (10)
gastroenteritis/duodenitis (K29) 2.2% (8)


Top 5 diagnoses of in patients (n=106)
angina pectoris (I20) 2.8% (10)
acute myocardial infarction (I21) 2.0% (7)
heart failure (I50) 1.4% (5)
stroke (I63) 1.4% (5)
acute renal failure (N17) 1.1% (4)


Table 1: In-hospital course and diagnoses of patients with low MTS category


Pr Anna SLAGMAN (Berlin, Germany), Johann FRICK, Julia SEARLE, Pr Möckel MARTIN
08:30 - 17:40 #11081 - EMERGENCY DIAGNOSTIC OF ENCEPHALOPATHIES.
EMERGENCY DIAGNOSTIC OF ENCEPHALOPATHIES.

Male, 38 years old. His past medical history was craniopharyngioma underwent surgery 30 years ago and its consequences as panhypopituitarism and diabetes insipidus. On treatment with hidroaltesone, levothyroxine, genotonorm, testosterone and desmopressin.

He was treated at the emergency room. He complained of weakness in the lower limbs and progressive sleepiness. Last week, he complained left arm tremor, without tongue biting or urine incontinence.

Clinical examination: Blood pressure 125/78 mmHg. Temperature 33ºCelsius. Stuporous. Glasgow coma scale: 7. Osteotendinous reflexes non valuables because of tonic manner. Sole reflex with removal. No stiff neck. Cardyopulmonary auscultation did not reveal any alterations.

Blood test showed bicitopeny (leukopenia and trombopenia) and hypoglycemia. Chest X-ray and electrocardiogram did not show any alterations. Brain imaging (Computed axial tomography) did not show any complications respect to neurosurgerys’s consequences. Electroencephalogram (EEG) showed Frontal Intermittent Rhythmic delta activity (FIRDA), without non convulsive status epilepticus.

Patient was diagnosed with encephalopathy due to panhypopituitarism with poor pharmacological control.

Corticoid treatment and hormonal prior treatment was administred to the patient.

It is essential to rule out epilepticus status in case of encephalopathy with a neurosurgery  history and abnormal movements. In the other hand, it’s very important suspect encephalopathy’s metabolic causes in patients with panhypopituitarism. To differentiate both, it’s necessary perform a urgent EEG.

EEG shows diferents types of activity. FIRDA usually occurs with toxic or metabolic encephalopaties. In the other hand, OIRDA (Occipital intermittent rhythmic delta activity) is present in hyperventilation children, and TIRDA (Temporal intermittent rhythmic delta activity) occurs in case of structural brain lession.

In brief, with patients with hormonal diseases history, with abnormal movements or encephalopathy, is very important discard epilepticus activity as metabolic encephalopathy. To urgent  diagnosed of encephalopathies is useful EEG test to discern differents diseases as status epilepticus or metabolic-toxic encephalopathy.

 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11920 - Emergency Medical Dispatcher Centers and elderly patients : a multicenter cohort study.
Emergency Medical Dispatcher Centers and elderly patients : a multicenter cohort study.

Elderly patients are increasingly using emergency department but this population also uses the Emergency Medical Dispatcher (EMD) Centers. However their share in the regulation activity has been little studied. Among medical issues, these patients are often polypathologic and experience loss of autonomy (requiring home care in order to stay at home). Dependence is a factor of fragility and severity associated with a higher mortality and morbidity. The characteristics of elderly patients calling the (EMD), their loss of autonomy and the existence of home carers have been little studied. The severity and fate of these patients are not known. We want to investigate the characteristics of this population and what do they become after EMD call (moratlity, admission). Moreover we want to the usefullness of collecting autonomy and home carers data in the first evaluation by medical dispatcher.

Method: Prospective multicenter cohort study on a given day in 54 EMD Centers. Patients ≥ 80 years old calling the EMD were included and questionnaires were completed by the medical dispatcher himself while answering on the phone. It dealt with autonomy, home carers, patient characteristics, calling characteristics, means triggered, care and situation on day 30. The main objective of the study was to assess the mortality rate at day 30 at most after calling the EMD. Secondary objectives were to analyze the fate of patients (death, hospitalization, institutionalization) according to the usual autonomy level and home carers existence. We performed statistical analysis through descriptive statistics and logistic regressions (adjustment on sex, age, autonomy, comorbidites, severity).

Results: n = 1608 patients were included corresponding to a heterogeneous part of the callers (0.9% to 44% according to the centers). The average age was 87 +/- 4.8 years, 63% were women. 75.7% of the patients lived at home (53% with home carers). 5.9% had no medical history, 5.3% had no daily treatment at all and 33.6% had cognitive impairment. Of the patients living at home, 33% were Knaus A and 19% Knaus≥C. 69,5% of the calls came from home. 29.3% of the reasons invoked were trauma. In 85% of the cases means were triggered by the dipatcher (73,4% of ambulances / firemen). At day 30, the mortality rate of patients was 8.1% and 50.8% had returned home.

There was no differences in mortality between the cared and non-cared groups (ORa=1.05 [0.48;2.30]). Having home carers reduces the risk of being hospitalized or institutionalized at day 30 (ORa=0.52 [0.30;0.89])


Conclusion: The majority of elderly patients calling the Emergency Medical Dispatcher Centers live at home. 19% of them have an important loss of autonomy and half of calling patients have home care. At day 30, 8.1% died and 50.8% returned home. Having home carers is associated with a lower risk of being hospitalized or institutionalized at day 30 following a call to the EMD Center.

 


Anne-Laure FERAL-PIERSSENS (Bobigny), Gustave TOURY, Fatima SEHIMI, Clement CARBONNIER, Marie BALLESTER, Philippe JUVIN
08:30 - 17:40 #11562 - Emergency Medical Intervention for Toxic Alcohol Poisoning.
Emergency Medical Intervention for Toxic Alcohol Poisoning.

Background: Patients ingesting ethylene glycol, isopropanol, methanol ('toxic alcohols') often show non-specific but very severe signs and symptoms. Positive diagnosis of toxic alcohols has traditionally been by gas chromatography (GC), a technique not commonly performed on-site in hospital clinical laboratories. The objectives of this retrospective study were: to assessed the incidence, mortality and the influence of emergency treatment on the survival rate from toxic alcohol poisoning (ethylene glycol, methanol and formaldehyde).

Methods: Retrospective, observational study was developed within the Emergency Department ( ED) of the “St. Spiridon” Emergency County Hospital, over a 15 weeks period, between January 1st 2017 and April 15th 2017, including the patients with toxic alcohol intoxication (confirmed by anamnesis or specific serum toxic alcohol level). We evaluated the patients’ profile, the mortality rate and the implementation of different therapeutic interventions. We also outlined different time intervals parameters, type of intoxication (accidental or with a suicidal intent). Statistic was done using SPSS.

Results: Out of the 21 cases of toxic alcohol intoxication – 16 were with ethylene glycol, 1 with formaldehyde 37%, 5 with methanol. 16 cases were confirmed qualitative with blood toxins by gas chromatography. The male-female distribution was 15:6, urban – rural 8:12; accidental intoxication – voluntary ingestion rate 14:7. Out of the cases of voluntary ingestion with a suicidal intent, 6 proved to be with ethylene glycol and 1 with formaldehyde 37%. 

The analyses of the data showed that 14 out of 21 patients were chronical ethylic alcohol consumers or have had a pre-existent liver disorder, such as liver cirrhosis and/or toxic hepatitis.

We registered 14 deaths – 10 with ethylene glycol poisoning and 4 with methanol poisoning. 4 of the 21 patients were found in cardiac arrest on the intervention site and 10 of them with alteration of mental status. In the ER, 14 patients had acute kidney failure with an average creatinine of 1.71 mg/dl and severe lactic acidosis with an average lactate of 15.31 mmol/l and  pH average of 7.02 and they received hemodialysis or hemofiltation. 10 patients received ethanol orally/ nasogastric tube as antidote in ED, 100% sodium bicarbonate and 95% received thiamine. Compared to survivors with complete recovery, patients poisoned with ethylene glycol that died  were more likely to exhibit clinical signs such as coma with GSC < 8 (p<0.05) and kidney failure and metabolic disorders: high creatinine level ( (p<0.05) and severe acidosis  (p<0.01).

Conclusions: All the patients included in our study received specific emergency treatment for toxic alcholol intoxication (sodium bicarbonate, ethylic alcohol and/or hemodialysis). The status in the first moment of ED presentation was very severe for majority of the intoxicated patients and the mortality very high (67,7%).


Diana CIMPOESU (IASI, Romania), Adrian NISTOR, Cristina STAN, Marius STRUGARU, Paul NEDELEA, Adrian COVIC
08:30 - 17:40 #11239 - Emergency Mobile Services’ accessibility constraints and delayed time to patient contact in deprived neighborhoods: the architectural missing link to urgent healthcare inequities? A prospective cohort study.
Emergency Mobile Services’ accessibility constraints and delayed time to patient contact in deprived neighborhoods: the architectural missing link to urgent healthcare inequities? A prospective cohort study.

Background

Emergency Mobile Services’ (EMS) response times condition the outcomes of several urgent pathologies. Yet, EMS response times are poorly defined to date, as they are classically measured from activation until ambulance stop. Current practices lack to consider the supplementary time from the parking of the ambulance until patient contact (walking access). Terminal accessibility constraints may alter EMS walking access, therefore increasing time to patient contact. In urban settings, accessibility constraints seem to prevail in areas with low socioeconomic status. This could partly explain the link between low socioeconomic status and poor outcomes in urgent time-dependent pathologies. We aimed to evaluate the link between EMS accessibility constraints, socioeconomic status of the scene location and time to patient contact.

Methods

We created a multicenter registry and prospectively collected data on every EMS interventions in a French urban area, including: standard intervention data, every time interval until patient contact (dispatch, activation, parking of the ambulance, patient contact), and EMS terminal accessibility constraints (either vehicular or on foot). We compared the time to patient contact depending on the existence of accessibility constraints and on the SES of the scene location (using quintiles of the French-EDI deprivation index, from Q1 less deprived to Q5 most deprived). We then conducted a mixed multivariate linear regression on the time to patient contact.

 

 

Results

1019 EMS interventions were included between July 1st, 2016 and April 1st, 2017, by EMS of the two district hospitals hosting ambulances. Overall mean time between ambulance arrival and patient contact was longer in case of accessibility constraints encountered by EMS (3.3±2.0 min vs. 1.8±1.1 min, p<0.001). In deprived areas (Q4 and above), accessibility constraints were more frequent (p<0.001) and time to patient contact was longer (constraints absent: 2.6±1.9 min vs. 2.20±1.5 min, p=0.001; constraints present: 3.5±2.1 min vs. 3±1.7 min, p=0.01). After multivariate linear regression, EMS time to patient contact was longer in multistory buildings located in deprived areas (Q4 and above, p<0.001).

Discussion

EMS terminal accessibility constraints were more frequent, and lead to higher time to patient contact, in urban deprived areas. This could be one of the missing links to poorer outcomes in urgent time-dependent pathologies occurring in these areas. Future Public Health interventions should be focused on improving EMS accessibility in deprived areas to yield equity in prehospital urgent care.


Matthieu HEIDET (Créteil), Thierry DA CUNHA, Charlotte CHOLLET-XÉMARD, Jean MARTY, Eric LECARPENTIER, Etienne AUDUREAU, Elise BRAMI
08:30 - 17:40 #11191 - Emergency MSE (eMSE) vs. full psychiatric assessment of patients with mental health presentations.
Emergency MSE (eMSE) vs. full psychiatric assessment of patients with mental health presentations.

Background

According to the Royal College of Emergency Medicine, ED Mental Health clerking in the UK is commonly poor. Patients presenting to the ED with mental health issues should have a Mental State Examination (MSE) completed. Without a prompt, doctors may omit findings that inform risk. Guys and St Thomas’ (GSTT) ED uses a Proforma which includes an Emergency MSE (eMSE). Using this, the assessor selects responses under each heading of a standard MSE. Our aim was to test the validity of the eMSE in accurately assessing patients with mental health presentations.

Methods

We compared eMSEs and MSEs completed during full assessments by the Liaison Psychiatry team. We used a cohort of 30 consecutive patients attending GSTT A&E from 01/01/2017, categorised as “mental health” on the Symphony ED software programme. We included patients who had an eMSE in their Symphony record and a corresponding MSE on the South London and the Maudsley (SLaM) Electronic Patient Journey System (EPJS). The eMSE response for each heading was compared with the EPJS assessment. Where eMSE and EPJS agreed a score of 1 was given, where they disagreed a score of 0 was given and where data was absent value x was given. Excel Spreadsheets were used to calculate percentage agreement overall and for each heading (excluding x data points). Using Excel we calculated Cohens Kappa (k) values for eMSE-EPJS agreement for each heading. Agreement tables were made for each heading, with responses grouped into three categories. From this we calculated observed proportional agreement (pO), probability of random agreement (pe) and k was calculated using the formula k=(pO–pe)/(1–pe)=1–(1–pO)/(1-pe).

Results

Overall agreement between eMSE and EPJS assessments was 63.7%. Using standard Cohen’s Kappa values, agreement was good (k<0.80) for Risk to Others (k=1, 100%). Moderate (k=0.41-0.6) for Appearance (k=0.52, 88.5%) and Risk to Self (k=0.46, 66.7%). Fair (k=0.21-0.40) for Behaviour (k=0.30, 57.7%), Mood (k=0.27, 81.8%), Thought (k=0.27, 50%) and Insight (k=0.35, 58.8%). Agreement was poor (k<0.20) for Affect (k=-0.17, 27.8%), Speech (k=-0.01, 36.4%), Cognition (k=-0.18, 68.8%) and Perception (k=0.06, 42.9%).

Discussion

Our results show that the eMSE has some overall agreement with the MSE in a full Psychiatric Assessment. The crucial areas of Risk to Others and to Self, had Good and Moderate levels of agreement respectively. The ability to quickly and accurately assess risk is of great utility in the ED.  Moderate agreement was observed for Appearance. Fair agreement was observed for Behaviour, Mood, Thought and Insight. These are essential for creating an impression of a patient’s mental state. Use of the eMSE facilitates fair and safe assessment of Mental State in the ED. Areas where agreement was poor may be difficult to reliably assess during a short consultation. Agreement in these categories may improve with refinement of eMSE options in line with more common responses in EPJS assessments.


Lawrence HUTCHINSON (London, United Kingdom), Dana KHORIATI, Victor COOKE, Savvas PAPPASAVVAS
08:30 - 17:40 #11346 - Emergency physician and reservist: what does that entail, exactly?
Emergency physician and reservist: what does that entail, exactly?

The French Health Reserve is a corps of French-speaking volunteers (it is not necessary to be French national) composed of the full spectrum of healthcare providers. This pool of caregivers and others specialists has been created to reinforce sanitary facilities and help meet the manpower need in exceptional sanitary situations. To assure its mission, this corps needs an important roster. But a lot of potential volunteers hesitate to enroll, considering that they will not be available for operations. The goal of this study is to show what exactly happens to an emergency physician enrolled in the French Health Reserve.

The first step of this study is a descriptive analysis based on demographic data of the emergency physicians (EP) in the Reserve, obtained from the last data reports. The second step is a descriptive analysis of the involvement of EP in operations over the last 2 years.

303 emergency physicians are registered in the reserve.  46 are enrolled, 203 need to update their contract, and 40 have an expired contract with need of renewal. 53% of them are women. The mean age is 46 years.  In 2015, 23 emergency physicians participated in missions or trainings with our institution, 16 in 2016. Over these 2 years, the mean length of time dedicated to mission or training per doctor (considering only those who participated) per year is 13 days [1-71].

Our pool of reservists is older than the national pool of EP (mean age 45 years), but younger than the other physicians in the reserve (mean age 54 years).  There are more women in the reserve than in the général population of EP in France where women represent 38% only of these specialists. Less than half our reservists really enroll in trainings or missions, without any consequences for those who do not. If they decide to attend a training course or to serve in one of our missions, the impact on their workload can be managed since the reserve offers opportunity of short trainings and short missions, even abroad.

Not being available is a very bad reason not to enlist since availability is not a prerequisite, and enlisting comes with the possibility to seize an opportunity whenever available. One EP participation in mission with us comes at a cost for employers and ED heads but with big rewards in terms of training and exposure to exceptional situations that help make the reservist EP more sensitive to the management of these situations and, by sharing experiences with the other members of the team deployed, make him realise that the grass is not always greener on the other side of the fence.


Sophie MONTAGNON (New York), Clara DE BORT, Melissent LUCAS, Philippe BOURRIER
08:30 - 17:40 #11448 - Emergency physician as shift leader in emergency department.
Emergency physician as shift leader in emergency department.

Introduction

Specialty of Emergency Medicine (EM) with a six-year specialist training program was established in Finland at the beginning of 2013. In addition to 71 specialists graduated during the transition period 2013 we have now nationally eight new EM specialists. They had already been working at Emergency Department (ED) before 2013. Earlier, in the front line of ED there were no regular doctors. EDs were run by junior doctors from different specialities like Medicine, Surgery, Neurology and General Practice.

Kanta-Häme Central Hospital is located in Southern Finland and covers the area of about 175 000 inhabitants. The ED has about 44 000 visits in a year. After establishment of EM specialty, we have developed our main processes in the ED. Three (of eight) new EM specialists are working in our ED at present. At the beginning of April 2017 they started to work as a shift leader during the day shifts. As a shift leader they act as an operative leader of the ED and a consultant for junior doctors, are responsible for treatment of patients with vital organ dysfunction or major trauma, coordinate emergency transfers to tertiary hospital, act as consultant for triage nurse, and assist in procedures including difficult cannulations, procedural sedation, and placement of pleural drainage.

 

Material and methods

This is a narrative study aiming to describe first experiences of Emergency Physicians (EP) working as a shift leader. Every newly graduated senior EP (n=3) was interviewed at the end of April 2017.

 

Results

According to EPs, the shift leader practice was a good way to fill previous lack of practical daily management and coordination. Junior doctors had quite a lot of questions concerning working practice at ED and patient management. Initial treatment of most difficult patients became more fluent and mental stress of junior doctors seemed to relieve. Teamwork with nursing staff in critical situations has become more organized after involvement of senior doctors. There are several procedures daily, where junior doctors need senior assistance. “Ping-pong diplomacy” between specialties during emergency process almost ended, because nowadays triage nurses have backup for their decisions. There were no emergency transfers to tertiary hospitals during April 2017. EPs also revealed mandatory things to take care at ED that did not use to have doctor assigned for.

 

Conclusion

EPs found the new shift leadership useful. They felt that the flow of emergent patients was more fluent and that junior doctors got help they had been lacking.


Jarno NASKALI (Seinäjoki, Finland), Teemu KOIVISTOINEN, Ville HÄLLBERG, Ari PALOMÄKI
08:30 - 17:40 #11684 - Emergency physicians, palliative patients and thromboprophylaxis: what are we doing?
Emergency physicians, palliative patients and thromboprophylaxis: what are we doing?

The relationship between thromboembolic disease (VTE) and cancer is well known, but this is not the case in patients who are followed by palliative care programs who are admitted to the hospital for acute medical conditions. However, it is becoming more frequent to enter these patients for medical reasons in the Emergency Departmens (ED), which implies the evaluation of the need to initiate VTE prophylaxis.

 

OBJECTIVES

To evaluate the opinion of the physicians who works in the ED about the use of thromboprophylaxis and the most frequent factors of withdrawal in palliative patients.

 

To analyze the most indicated doses of heparin, the possible use of direct acting anticoagulants (DOACs) or compression stockings in these patients, as well as the most adequate duration of treatment.

 

 

RESULTS

518 questionnaires were obtained. 53.7% were women. Age: 64% under 45 years old. Only 16% worked at pre-hospital units.

The health professionals consider prophylaxis of VTE very useful measure in palliative patients (78.2%). Less than 5% do not take into account the patients' opinions about whether or not to start treatment, especially women (0.016), and less than 10% disregard patient´s functional status (more than 55 years old -0.006) and more of 87% do not take into account the cost of treatment, particularly those over 55 years old (0.034) and those working in ED (0.006).

 

70% of the emergency´s professionals consider that it is not a measure that is taken into account to the discharge of patients from ED, but when they do, complete doses of heparin were prescribe  (60.6%), especially women (0.047) and those who works in hospitals ( 0.006). DOACs are an option for doctors over 55 years old (0.038) and compression stockings for those under 35 years old (0.035).

They think that treatment should continue as long as a risk factor for VTE was maintained (73.5%) and if it is to be withdrawn, the patient's functional situation is decisive (58.9%).

 

CONCLUSIONS

The prophylaxis of VTE is not a measure that is usually prescribed for the discharge of ED, although emergency physicians consider that palliative patients could benefit from it, not being a factor that influences the onset of the treatment cost. As far as the reason of withdrawal that more is taken into account is the functionality of the patient.


Marta MERLO (MADRID, Spain), Isabel BLASCO, Pedro RUIZ-ARTACHO, Daniel SÁNCHEZ, Jorge CASTILLO, Sònia JIMENEZ
08:30 - 17:40 #11657 - Emergency physicians, palliative patients and thromboprophylaxis: where do we come from and where do we go.
Emergency physicians, palliative patients and thromboprophylaxis: where do we come from and where do we go.

The relationship between thromboembolic disease (VTE) and cancer is well known, but this is not the case in patients who are followed by palliative care programs who are admitted to the hospital for acute medical conditions. However, it is becoming more frequent to enter these patients for medical reasons in the Emergency Departmens (ED), which implies the evaluation of the need to initiate VTE prophylaxis.

 

OBJECTIVES

To analyze the opinion of emergency physicians on the frequency of VTE in palliative patients, the impact on quality of life, survival and the need for prophylaxis when they remain in the hospital due to acute medical illness.

To evaluate knowledge about indications of clinical practice guidelines (CPG) or the presence of risk assessment scales on VTE events.

 

 

METHODS

Longitudinal, prospective and multicentric study was done. An anonymous online survey was sent to physicians who work in the emergency services, both hospital and out-of-hospital. It included twenty questions about the frequency of VTE, the need for prophylaxis, the doses and factors related to the initiation or withdrawal of VTE in patients under paliiative care programs.

 

RESULTS

518 questionnaires were obtained. Characteristics of population:53.7% were women. Age: 64% under 45 years old. Only 16% worked in out of hospital.

They considered that VTE is very frequent in palliative patients (84%), predominantly women (0.045) and those younger than 35 years. In general, they were thinking that VTE produce relevant symptoms (96.5%) and that it influence quality of life (96.3%) and survival (79.5%), and therefore, prophylaxis of VTE in palliative patients. However, less than 5% considered that VTE is a way to "die well" for palliative care patients.

Regarding predictive scales, 28% of them answered that there are specifics scales in palliative patients, especially women (0.004) and those over 45 years old (0.015). They also answered that there are special recommendations for palliative care patients in clinical practice guides (58.5%), especially those professionals who work in hospitals (0.038).

 

CONCLUSIONS

Emergency physicians consider VTE as an important pathology that affects the patient's evolution, but they have doubts about the integral approach of Palliative Care and the recommendations of the CPG, both of which are areas for improvement in Emergency departments.


Marta MERLO (MADRID, Spain), Isabel BLASCO, Pedro RUIZ-ARTACHO, Albert ANTOLIN, Montserrat DURAN, Sònia JIMENEZ
08:30 - 17:40 #10468 - Emergency Radiology in Pregnancy.
Emergency Radiology in Pregnancy.

Emergency radiology during pregnancy has always represented a challenging decision to the emergency physician. Not only because of the effects of ionizing radiation to the mother but also because of the potential harmful effects to the unborn fetus. In order to understand these challenges, it is important to review some facts about the radiation effects. The normal human immunologic system has the ability to detect, repair or destroy cells with damaged DNA. This system can be overwhelmed by large and/or repetitive doses of radiation leading to increase risk of malignancies. However, the information available on the effects of ionizing radiation is less than perfect. Currently, there are no randomized studies evaluating the dose-effect of radiation in humans.  All data comes from observational studies, phantom models and extrapolation of nuclear disasters. Utilizing the aforementioned limited data seems to be sufficient to formulate some conclusions. The background dose of radiation for a 9-month pregnancy is estimated at 0.5 to 1 mSv (depending on location and altitude) and the threshold for increased risk of fetal anomalies or pregnancy loss has been calculated at 50 mSv. The standard radiological tests produce radiation doses far below 50 mSv. The National Council on Radiation Protection and Measurements, and the American College of Obstetrician and Gynecologists have both agreed that the potential health risks to a fetus are not significantly increased from most standard medical tests. In the emergency department, the important diagnostic conundrums in the pregnant patient in which radiologic studies are likely to be used include: Abdominal pain rule-out appendicitis, renal colic and urolithiasis, gynecologic disorders (ovarian torsion, adnexal mass, hemorrhagic cysts and degenerating fibroid), pulmonary embolism and trauma. Using diagnostic imaging appropriately, having informed decisions with our patients and clearly documenting all discussions will make us good stewards of these useful resources. 


Dr Adan ATRIHAM (Houston Texas - USA, USA)
08:30 - 17:40 #11937 - Emphysematous cystis revealed by septic shock.
Emphysematous cystis revealed by septic shock.

Introduction:

Emphysematous cystitis is a rare infectious disease. The early making diagnosis is a challenge for emergency physician and remains difficult because of its polymorphism at clinical presentation.

Observation:

We report a case of 63 years old man with medical history of prostatic hypertrophy and a stroke who was admitted in the emergency department for dizinness evolving within last 24 hours. On examination, patient was confused , sleepy with generalized marbling, polypneic with pulse oximetry on air = 90% and blood pressure = 90/40 mmHg and tachycardia = 145 bpm.  Hyperlactatemia was noticed on blood gaz sample. Biology analysis showed : hyperleucocytitis, renal and hepatic failure The abdominal examination was marked by distension. An abdominal tomography showed an aspect of emphysematous cystitis .The patient received antibiotics and circulation was optimized by fluid resuscitation and vasoactive drogues introduction. ufortunately evolution was fatal at day 3 after presentation.

Conclusion:

Emphysematous cystitis is a  serious pathology.It had a high risk of mortality despite an adequate therapy.


Wided DEROUICHE (Tunis, Tunisia), Hamed RYM, Alaa ZAMMITI, Badra BAHRI, Mohamed KILANI, Maroua MABROUK, Héla BEN TURKIA, Chokri HAMOUDA
08:30 - 17:40 #11494 - Emphysematous Cystitis: a case report.
Emphysematous Cystitis: a case report.

A 57 years old female, with a history of metastatic lung carcinoma was admitted to the Hospital after a thoraco-abdominal CT scan that showed esophageal stent dislocation.The patien thad right lung carcinoma with multiple metastases ( lung, lymph nodes, pleura and brain) with aninfiltration to the esophagus, and she had an esophageal stent. In the emergency room the patient was stable, eupnoic and her vital signs were normal. The CT scan revealed the presence of large amount of gas in the retroperitoneum, in the abdominal cavity, gluteal and right thigh root level. EGDS was performed with stent removal and another abdominal CT scan confirmed the presence of retroperitoneal gas at para and sopravescical sites with global bladder wall involvement. The surgeon did not advice for urgent surgical intervention and the urologist inserted a bladder catheter and adviced an endoscopic examination (cystoscopy) after antibiotic therapy (metronidazole and piperacillin /tazobactam) in case of clinical deterioration. The patient was admitted to the medical ward with progressive painand radiological findings resolution.

Emphysematous cystitis is a rare infection of the urinary bladder produced by gas forming uropathogens. Escherichia coli and Klebsiella pneumoniaare the predominant pathogens. The major risk factor is diabetes mellitus. Risk factors include also a neurogenic bladder, urinary tract obstruction and being of female sex.Emphysematous cystitis is a relatively rare condition that has a significant mortality rate of 7%.

Abdominal pain is the major clinical manifestation.The best diagnostic tool is abdominal CT,which may demonstrate the extent and the location of the gas collection in and around the bladder wall, or an air-fluid level in the bladder. Emphysematous cystitis can complicate with the bilateral emphysematous iliopsoas abscesses. Therapy is essentially large spectrum antibiotic.

References:

  • Tal M.; Avi S.; Roni M.; Yoram D. Demonstrative Imaging of Emphysematous Cystitis. Urology Case Reports 6 (2016) 56-57.

  • Meriam I.; Aaron Singh B.; Owen I. Emphysematous cystitis: a radiographic diagnosis. BMJ Case Rep 2016. doi:10.1136/bcr-2016-214455.

  • Sung-Yuan H.; Bor-Jen L.; Che-An T.; Ming-Shun H. Concurrent emphysematous pyelonephritis, cystitis, and iliopsoas abscess from discitis in a diabetic woman. Medical Imagery- International Journal of Infectious Diseases; 51 (2016) 105–106106.


Fabrizia NATUCCI (florence, Italy), Germana RUGGIANO, Mattia BARTALINI, Guido TOTA, Stefano BARATTI, Benedetta CHELLINI
08:30 - 17:40 #10990 - Endocarditis and Spondylodiscitis due to a Rare Organism: A.Defectiva.
Endocarditis and Spondylodiscitis due to a Rare Organism: A.Defectiva.

A 60-year-old man was admitted to our hospital because of 3-4-months remitting and relapsing fever, especially in the evening, night sweating, weakness, joint pain and myalgia. He had no dyspnea, cough, thoracic pain, palpitation or skin abnormalities. There was  a history of orthodontic appliance but no history of previous cardiac disease, drug/alcohol abuse, smoking or travel. Upon admission, the patient was apyretic; he had a pulse rate of 88 beats/min, BP 147/75 mmHg, room-air oxygen saturation of 95%. Physical examination revealed a 3/6 pansistolic murmur heard at the apex. Laboratory investigations showed a raised C-reactive protein of 3.4 mg/dL (normal range: 0-0,7 mg/dL), with a normal count of leukocytes of 8,43 migl/mmc (normal range: 4-10,90 migl/mmc).  Blood culture was positive for Abiotrophia Defectiva, very rare but associated with high rates of complications and mortality. Transthoracic and transesophageal echocardiography demonstrated large vegetation attached to the posterior cusp (in particular p2) and to the anterior cusp of the mitral valve, with wide perforation and moderate-severe  regurgitation,  requiring  early surgical resection of the vegetation and valve replacement with a mechanical prosthesis, which was both performed. The procedure was complicated by a  III degree AV block which required a permanent PM. A cerebral computed tomography was performed without signs of embolization while Abdomen CT demonstrated a single septic localization in left kidney. Spinal RM showed signs of initial L3-L4 spondylodiscitis. Treatment with intravenous dose of ampicillin and gentamicin iv was started and continued for 5 weeks , lately switched to levofloxacin orally for 4 weeks. Anticoagulation was performed with warfarin, maintaining international normalized ratio between 2.5 and 3. Thereafter, the patient remained well on the out-patient follow-up. In non-addicted patients, several states such as alcoholism, immunodeficiency states, intracardiac  devices, congenital heart diseases can provide the predisposing factors for endocarditis.  We report a rare case of isolated mitral valve endocarditis without these predisposing factors. This work highlights the sneaky presentation and the difficult in finding the correct antibiotic therapy, due to the extreme rarity of this infection. Although few cases of Abiotrophia defective infective endocarditis have been reported, the majority have resulted in valve replacement despite adequate antibiotic therapy, as in our patient. To our knowledge, spondylodiscitis as a manifestation of A.defectiva infection, is rarer than endocarditis in literature. It is important to be aware of this aetiological agent, as prompt and aggressive treatment and a multi-disciplinary approach is necessary to improve outcomes.



Sabrina LUPACCIOLU, Luca RONCUCCI, Piero BENATTI, Francesca MORI (MODENA, Italy), Francesco LUPPI, Brugioni LUCIO
08:30 - 17:40 #11846 - Epidemiological profile of acute poisoning during pregnancy.
Epidemiological profile of acute poisoning during pregnancy.

EPIDEMIOLOGICAL PROFILE OFACUTE POISONING


Fatnassi MERIEM, Khzouri TAKOUA, Ben Jazia AMIRA, Sedghiani INES (tunis, Tunisia), Brahmi NOZHA
08:30 - 17:40 #11692 - Epidemiological trauma caused by traffic injuries in children admitted in Fatemi hospital, Ardebil.
Epidemiological trauma caused by traffic injuries in children admitted in Fatemi hospital, Ardebil.

Background: Accidents are one of the greatest dangers that threaten children’s lives. It is reported that 85 % of mortality in children is related to accidents worldwide. Trauma is the leading cause of child mortality in developing countries and the most common cause of trauma is motor–vehicle related accident .Unfortunately ,in 70-75% cases ,damage in children occurs in their face and head. This study was aimed to investigation epidemiological study of traffic injuries in children admitted in Fatemi hospital, Ardebil .

Methods: In this cross-sectional study, medical records of all children under 15 years who  admitted to the emergency ward of Fatemi hospital trauma during the years 2012 to 2015 were studied, questionnaire which contains information about the type of trauma, sex, age, anatomical location of the damage, length of stay and mortality rate were collected. To investigate the use of seat belts, front passenger and rear, the cultural level of the family and vehicle type was recorded in the patient questionnaires. Data analysis was performed using SPSS software version and the relationship between death and the other study variables were used chi-square and t tests

Results: The results showed that the mean age of the affected children were (7/64 ± 4/16) years and most (37/7%) were  in  the lowest age range 6-10 years ، (26/2%) in the age range 11-15 years.From a total of 263 children that visited  at the emergency departments because of motor–vehicle related accident, 65/4% were male and 34/6 % were female The musculoskeletal injuries included foot% (39/7), head and neck (%28/5), multiple trauma (%12/5), Hand (%11/3), chest (6%)and abdomen organs (2%).The injuries from motorcycles hitting pedestrians and, car–pedestrian accidents was higher than the rest.48% of victims at the time of the accident  aboard the vehicle and 52% were pedestrians.

No significant differences were seen regarding the settlement of the child in the car ، type of trauma، in urban and residential areas with the Riding on vehicle and pedestrian injuries. Pride, Peugeot Family Group, roa, peykan, Samand, Nissan, Pickups, motorcycle and Rest of the car respectively had the highest roles  in accidents. More parents of the victims were high school graduates or academic Degree.67% of injuries seating ride on car, was in the rear cabin. Accident rate was higher in urban areas than outside residential areas. The results of this study show that, unfortunately, the use of safety belts among the victims of the accident was very low (3, 4/2%).

Conclusions: Children who are walking more vulnerable than children who are riding the vehicle, therefore it is important that parents are more careful on their children when walking in the streets. Unfortunately, the use of safety belts among the victims of the accident is very low and it is necessary to pay more attention to parents for using a child seat in the car


Saed SADEGEH AHARI, Rezvan PASHAZADEH, Effat MAZAHERI (tabriz, Islamic Republic of Iran), Mohammad ESMAILI DELSHAD, Jafar GOBADI, Amir Ahmad ARABZADEH, Farnaz RAHMANI
08:30 - 17:40 #11247 - Epidemiology and healthcare of patients with STEMI consulting their general practitioner instead of calling the EMS (15, 18, 112) first.
Epidemiology and healthcare of patients with STEMI consulting their general practitioner instead of calling the EMS (15, 18, 112) first.

Background: In case of ST- elevation myocardial infarction (STEMI), the strategy of reperfusion must be introduced by an early call to the Emergency Medical Dispatching Center (DC: 15-112-911). This prehospital regulation demonstrated its efficiency. In spite of public awareness programs, patients consult beforehand their general practioner (GP).

Objective: The aim is to define the epidemiological profile of these patients with STEMI of less than 24 hours and what they become after a call to the DC, whether by their GP (callGP) or directly (directDC).

Methods: Prospective prehospital registry, which included all patients with STEMI of less than 24 hours managed  primary  by 8 DC  and its 39 Mobile Intensive Care Units (MICU). Observed variables: epidemiological characteristics, conditions and delays of healthcare, location of the STEMI, complication, desobstruction decision and mortality. Univariate statistical analysis, significant test, Khi 2, p<0.05.

Results:  Between 2003 and 2014, 20221 patients were included, among which 2725 (13.5%), made the object of a call of a GP for the dispatching center of the Emergency Medical Service (EMS). Women (28.1% vs 20.9%, p<0.001), arterial hypertension (43.2% vs 40.6%, p=0.0382), inferior location (50.4% vs 47.2%, p=0.0022) were factors associated significantively to recourse the GP at first. In spite of coronary antecedents, 11.8% of the patients persisted in seeing in the first intention their own doctor. They presented fewer disorders of the rhythm or conduction (9.7% vs 12.6%, p < 0.0001), less use of   catecholamine (2.9% vs 4.2%, p=0.0013), less intubation (2.0% vs 3.9%, p<0.0001) and less cardio-respiratory arrest (3.2% vs 5.9%, p<0.0001) with same mortality (p=0.2428). The call of GP to the EMS for this indication started quasi-systematically a MICU at first (94,0%), but the desobstruction decision was less frequent (88.5% vs 93.9%, p<0.0001). Median time from symptom onset to reperfusion was GP = 280 [192;490] min vs directDC = 180 [137;276] min. Median time from sympom onset to call DC was GP = 151 [71;362] min vs directDC = 52 [22;138] min, p<0.0001. Median time from call DC to MICU was GP = 20 [15;29] min vs directDC = 18 [14;23] min, p<0.0001.

Conclusion: Too many patients suffering from STEMI still called their GP instead of calling this DC directly. Prevention campaign must target the GP and specific population, define by our result in order to reduce morbidity and mortality.


Steven LOVI, Hugues LEFORT, Alexandre ALLONNEAU, Aurélie LOYEAU, Isabelle KLEIN, Dr Abdo KHOURY (Besançon), Lionel LAMHAUT, Virginie PIRÈS, Gaelle LE BAIL, Sophie BATAILLE, Yves LAMBERT, Frédéric LAPOSTOLLE
08:30 - 17:40 #11523 - Epidemiology of deceased patients after their admission to the Emergency Department.
Epidemiology of deceased patients after their admission to the Emergency Department.

Background, aim

In order to evaluate and improve the performance of Emergency Departements (ED), mortality analysis is a powerful indicator and a tool conventionally used. The main objective of our work was to establish the epidemiology of patients who died up to 30 days after their admission to the Emergency Departement. The secondary objective was to specify our results about mortality at short (48 hours), medium (7 days) and long (30 days) term.

Methods

This was an observational, retrospective study carried out between the 07/01/13 and 06/30/14. Included: all patients admitted to the ED. Excluded: patients who arrived already dead and those directly admitted to the trauma shock treatment room. Clinical, biological, anamnestic, diagnostic, spatial and temporal data were collected from the patient's computerized medical record. The statistical analysis was descriptive and inferential.

Results

918 patients were included. The most commonly mentioned admission pattern is dyspnea (27.7%, CI [24.8-30.7]) and sepsis with a pulmonary starting point constituted the main diagnosis of discharge from the ED (19.5%, CI [17-22,2]). Intensive care units and the ED observation units recorded the majority of deaths (22.8%, CI [20.1-25.7], 14.9%, CI [12.7-17.4]). The main etiology of death was septic shock (15.6%, CI [13.2-18]). Chronic heart disease was found in patients medical history in 50.1% (CI [46.8-53.4]) of cases. The Glasgow score, oxygen therapy at the admission and lactate levels mesured in the first 24 hours were significantly associated with 30-day mortality (HR: 1.1 [1.04- 1.15], 1.3 [1.02-1.55], 1.1 [1.04-1.11]). In periodic analysis, the presence of cognitive impairment and an increase in lactate levels were associated with an increased risk of death before 48 hours (HR: 1.8 [1.04-3.25], 1.1 [1,05-1,19]). Reduced blood pH and altered Glasgow scores were associated with mortality before 10 days (HR: 6.7 [2.02-2248], 1.3 [1.08-1.56]).

Conclusion

Few studies comparable to ours have been carried out. The identification of predictive mortality factors suggests opportunities for improvement ; The establishment of a capillary lactate reader, coupled with a particular vigilance regarding the Glasgow score and the presence of oxygen therapy, would seem to be effective in predicting mortality.


Mélanie JACQUET (COLMAR), Sophie PINCEMAILLE, Anne-Charlotte MAISONNEUVE, Jean-Rémy SAVINEAU, Caroline BLETTNER
08:30 - 17:40 #11406 - Epidemiology of infection in elderly patients admitted to the emergency.
Epidemiology of infection in elderly patients admitted to the emergency.

Objective:

The study  aim was to describe clinical features of infection in elderly patients admitted in the emergency department.

Patients and methods:

Descriptive retrospective study including patients aged more than 65 years, admitted in the emergency department with documented infections and treated with antibiotics, during two years (2015-2016).

Results:

Sixty four patients were included. The average age was 75 years, 36 patients were females. Most patients had a past history of hypertension (37.5%), diabetes 18.8%, active cancer 26.6% and coronary diseases 7.8%. Fourty five percent of cases had more than three past history. Pnemonia was the first infection 35.9%, urinary tract infection was diagnosed in 34.4%  and skin infection in 14.1%. The average length of stay was 9 days. Thirty percent of patients had complications. Among them, 11 (17.2%) had required intensive care and 2 (3.2%) were dead within the first 24 hours.

Eighty percent of patients had Systemic Inflammatory Response Syndrome (SIRS) on admission, quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) was positive in 40.6% of patients and it was correlated with age (p=0.014).

Conclusion:

The severity of infections is common in elderly patients admitted to emergency department. It could be explained by the atypicity of infectious symptoms and the physiopathological characteristics at this age.

 


Saloua AMRI, Imene MEKKI (Tunis, Tunisia), Mohamed EL AHMED, Abdourrahman DIALLO, Sitafa COULIBALY, Fredj KAHNA
08:30 - 17:40 #11567 - Epidemiology of Urinary tract infections in the emergency department : 120 cases.
Epidemiology of Urinary tract infections in the emergency department : 120 cases.

BACKGROUND

Urinary tract infections (UTIs) are among the most common human bacterial infections in the Community. UTIs is a wide public health problem affecting people regardless the sex and the age of the patient, although they accur more among certain people than others. As a severe infection, UTI can cause kidney damage and can be life threatening. Bacterias are increasingly becoming resistant to currently available antibiotics leading to recurrent infections. The aim of this study is to discribe the epidemiology of the UTI’s and the profil of the infectious agents involved.

 

METHODS

A discriptive, prospective study enrolling during a period of 3 months, 120 patients with positive urine culture treated in the Emergency Departement (ED) of the military hospital of Tunis. A specific case report form (CRF) was created to collect the epidemiological, clinical, biologic and bacteriologic data, traitement and the issue of patients.

 

RESULTS

Among the 120 patients involved in this study, There were 77(64.2%) females and 43(35.8%) males. The mean age was 48.43 years [15-92]. Diabetes was found in 20.8 % of the patients,  history of a kidney stone in 15.8%  and a previous infection was found in 9.2% of the cases. Micturition burns, lomber pain and fever were the three most common clinical features of the infection in respectively, 59.2%,  33% and 28% of cases. The final diagnosis were cystitis 31.7 %, pyelonephritis 40.8 %, Prostatitis 11.7%. Asymptomatic bacteriuria was found accidentaly in 15,8 % of cases. Enterobacteriacae were the most frequently identified strains including ; Escherichia coli (62.5%), Klebsiella pneumoniae (8.3 %), Proteus Mirabilis (10 %). Antibiograms showed bacterial resistance to ampicilline in 67 % of the cases. Escherichia coli loss susceptibility to amoxicillin in 22 % of cases and to the association trimethoprim-sulfamethoxazole in 38 % of cases. However, Enterobacteracae remained sensitive  to ciprofleoxacin (78 %).

 

CONCLUSION

The UTI occurs more in young adult women. pyelonephritis was the most common diagnosis found. Enterobacteriacae was the most frequent bacterial strain. Resistance to antibiotics was highly observed.


Bassem CHATBRI (Tunis, Tunisia), Rafaa ALOUI, Sonia SLIMI, Mounir HAGUI, Yousra GUETARI, Rim HAMMAMI, Ines GUERBOUJ, Ghofrane BEN JRAD, Olfa DJEBBI, Mehdi BEN LASSOUED, Khaled LAMINE
08:30 - 17:40 #11007 - Establishing an effective and coordinated medical system for severely injured trauma patients.
Establishing an effective and coordinated medical system for severely injured trauma patients.

To save the life of severely injured trauma patients, establishing a 24/7 medical system is critical, with coordinated cooperation between emergency medicine, orthopedics, and radiology departments. The choice of treatment strategy, including treatment-related priorities, influences patient prognosis. Our facility has made strenuous efforts to establish such a system, successfully saving many lives. A key feature of our system is the active involvement of radiologists or interventionalists in the treatment processes starting from patient admission to their transfer to the primary care unit. They play a pivotal role in radiogram interpretation and deciding treatment-related priorities. We demonstrate the effectiveness of our system by presenting two lifesaving cases.

Case 1: An 81-year-old female was injured after she fell while being robbed. EMS determined that she was in a state of shock, and she was transferred to our department as her right radial artery was not palpable. The right axilla was extremely swollen; contrast CT revealed extravasation from the right axillary artery. Emergency interventional radiology (IVR) was performed. Blood flow was completely disrupted at the injured site, and coagulopathy rapidly developed. After performing coil embolization as a damage control IVR procedure, a vessel graft was surgically replaced. The patient was discharged for rehabilitation on the forty eighth hospital day.

Case 2: A 55-year-old male presented with hydrocephalus due to subarachnoid hemorrhage. VP shunting was performed. His blood pressure began to fall during the procedure, and he consequently entered a state of shock. Contrast CT revealed massive pleural fluid accumulation with extravasation. Chest drainage revealed a massive hemothorax. He was diagnosed with a right subclavian artery injury due to shunt passer penetration, and transferred to our department. Upon admission to the primary care unit, his blood pressure and hemoglobin levels were 40 mmHg and 2 g/dl, respectively. Emergency IVR was performed, and a covered stent was placed at the injured site. His condition stabilized soon after. The patient was transferred to a rehabilitation hospital after neurosurgical treatment.


Nobuaki KIRIU (Tokyo, Japan), Ichiro OKADA, Eiju HASEGAWA, Hisashi YONEYAMA, Kazushige INOUE, Hayato YOSHIOKA, Hiroshi KATO
08:30 - 17:40 #11490 - Estimation of preload response to passive leg raise using thoracic electrical bioimpedance in emergency department.
Estimation of preload response to passive leg raise using thoracic electrical bioimpedance in emergency department.

Background: In emergency department (ED), haemodynamic monitoring relies mainly on clinical and basic monitoring parameters (blood pressure and heart rate). It is important to carefully titrate treatment of shocked patients as under- and over-treatment are both harmful. Preload response to a fluid challenge or passive leg raise (PLR), a validated reversible self-fluid challenge, has been suggested as a more dynamic, controlled way of resuscitation. Thoracic electrical bioimpedance (TEB) is a non-invasive cardiac output monitor that can quantify the response to PLR, fluid responsiveness.1  While PLR has gained much interest in critical care, it has been little studied in ED.2

Aim: To determine the accuracy of PLR in predicting the haemodynamic response to a fluid bolus in ED.

Methods: A prospective, observational study will be carried out on 105 patients for who the usual care team have decided that a bolus of intravenous fluid is required. Patients will be monitored using TEB, a non-invasive cardiac output monitor using electrodes to the sides of the neck and lower chest. A PLR test (semi-recumbent followed by 45-degree leg raise for 3 minutes) will be performed before fluid administration. Monitoring will continue until the treating physician decides that no more fluid resuscitation boluses are needed. A further PLR test will be undertaken after each fluid bolus has been infused.

Discussion: As neither the clinical parameters nor the standard ED monitoring can reliably assess cardiac preload or predict fluid responsiveness, we hypothesise that combining PLR with TEB can provide additional information to inform clinical decisions. This study will obtain the information needed for the design of a future interventional clinical trial.

1. Monnet X, Marik PE, Teboul J-L. Prediction of fluid responsiveness: an update. Annals of Intensive Care. 2016;6(1):111.

2. Elwan MH, Roshdy A, Elsharkawy EM, et al. The haemodynamic dilemma in emergency care: Is fluid responsiveness the answer? A systematic review. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2017;25(1):25.

 


Dr Mohammed ELWAN (Leicester, United Kingdom), Ashraf ROSHDY, Eman ELSHARKAWY, Salah ELTAHAN, Timothy COATS
08:30 - 17:40 #11010 - European security in health data exchange. A challenge at emergency departments.
European security in health data exchange. A challenge at emergency departments.

BACKGROUND: Security is one of the main challenges when applied to eHealth and is crucial in the transmission of required data around patients and citizens when travelling around the world. This is the aim of European funded SHiELD project. One of the specific developments to be done in SHiELD is the end-to-end systemic analysis of potential risks to health data. This will be achieved by creating a knowledge base from potential threats including ‘classical’ cyber security threats, emerging threats to personal data, and compliance threats.

The main objective of the SHiELD is to create an open and extendable security architecture supported by security mechanisms and privacy to provide systematic protection for the storage and exchange of health data across European borders, while improving trust of patients in the security of their data.

METHODS: SHiELD will unlock the value of health data to European citizens and businesses by overcoming security and regulatory challenges that today prevent this data being exchanged with those who need it, especially in emergency situations when access to key data needs to be achieved in a short period of time. One of the European projects dealing with the security and interoperability of eHealth data is epSOS project’s that result is the OpenNCP architecture and implementation. The OpenNCP community has designed and developed a set of Open Source Components based on the services developed in epSOS that can be used by Participating Nations to build their local implementation of an NCP. However, this has not been validated and put into practice.

RESULTS: Validation scenarios (realistic use cases), will be supported by three different member states (Italy, United Kingdom and Spain). In all scenarios, we assume a citizen travels abroad and they need or demand health care; the foreign healthcare professional needs to access and/or manage patient’s health records. One of the scenarios that will be validated is an Italian citizen travelling to Spain that has acute emergency (e.g. stroke) and loses consciousness. Spanish emergency department suddenly assists the patient. After the first aid, the emergency doctor wishes to check the patient’s health record to know his/her medical history (e.g. epSOS patient summary). Will those data suffice? Which are the mandatory minimum data and how systems will secure them? SHiELD will also build upon examples: last known activities (e.g. mobile/wearables with heart rate, blood pressure,…) from “Get Active” in the United Kingdom.

DISCUSSION: Security challenges need to be addressed by the SHiELD project for the eHealth domain. As summary these challenges are: interoperability, confidentiality, availability, integrity, privacy, regulations and eHealth data (identify which data are going to be shared and by which mean). This will be used as the base for both the “in depth” requirements analysis for SHiELD as well as setting the main pillars for the SHIELD architecture detailed design.


Eunate ARANA-ARRI (Berango, Spain), Aitor GARCÍA DE VICUÑA, Miguel Angel OGUETA, Santiago RODRÍGUEZ, Oscar PEREZ, Ines GALLEGO, Maria Luz DEL VALLE
08:30 - 17:40 #9842 - Evaluating the Implementation of a Sepsis Pathway in the Emergency Department.
Evaluating the Implementation of a Sepsis Pathway in the Emergency Department.

 

Background: The importance of early management of sepsis is well known and has led to increased efforts in improving the recognition of and response to septic patients in emergency departments    

Objectives: To evaluate the impact of utilising a Sepsis Pathway Program, aimed at improving recognition of and response to septic patients, in a metropolitan Emergency Department 

Method: Following the introduction of a Sepsis Pathway Program in June 2015, a review of patients presenting to the emergency department of Casey Hospital, Victoria from June to December 2015 with sepsis was conducted. Main outcome measures were: time to antibiotic administration and to lactate measurement; rate and duration of intensive care admission; in-hospital mortality, and total duration of hospital admission. Outcomes were compared to a retrospective review of septic patients presenting to emergency from June to December 2014.

Results: The review included 171 patients in 2014 and 130 patients in 2015. The median time to antibiotic administration was significantly shorter in the post-intervention group (102 minutes vs. 190 minutes, p<0.05. The time to lactate measurement, number and duration of intensive care admissions, in-hospital mortality and total length of stay was not significantly different between the two groups.  

Conclusion: Implementation of the Sepsis Pathway Program resulted in earlier administration of antibiotics in septic patients presenting to the emergency department. Although a significant difference in secondary outcomes were not observed in this study, further evaluation in a larger multi-centre study may be warranted.


Dr Pourya POURYAHYA (Melbourne, Australia), Judy CHOW, Alastair MEYER, Neil GOLDIE
08:30 - 17:40 #10518 - EVALUATION ASSOCIATED WITH NURSING CARE IN PATIENTS WITH HIV-AIDS IN ORDER TO PROMOTE A BETTER UNDERSTANDING OF THE CONCERNS NURSING, GIVING A COMPREHENSIVE AND HOLISTIC NURSING CARE AND PATIENT PERCEPTION OF CARE FOR THIS.
EVALUATION ASSOCIATED WITH NURSING CARE IN PATIENTS WITH HIV-AIDS IN ORDER TO PROMOTE A BETTER UNDERSTANDING OF THE CONCERNS NURSING, GIVING A COMPREHENSIVE AND HOLISTIC NURSING CARE AND PATIENT PERCEPTION OF CARE FOR THIS.

Introduction: HIV / AIDS is a matter of great importance locally, nationally and globally because it is a disease that has affected the world and every day increased rates of morbidity - mortality in the entire society. The purpose of the study is evaluating  nursing care in order to promote a better understanding of the concerns, giving a holistic approach for nursing care and patient perception of this care.

Material and methods: This cross-sectional study type included 77 nurses from “Mother Teresa” Hospital Centre of Tirana and Regional Hospital of Vlora, also 55 patients diagnosed with HIV during the period 2013-2015. In both of these institutions were interviewed health service nurses and patients in infective and pediatric services. Data collected from questionnaires distributed were analyzed with SPSS statistical program (vs18.0).

Results: In total included 77 nurses, of whom 65 (84.4%) were female and 12 (15.6%) were male; and 55 patients, whose average age was 33.3 years with range 7,98 20- 55 years, of whom 24 (43.6%) patients were female, while 31 (56.4%) of were males. It has not resulted in statistically significant relationship between education level of nurses about the institutions where they work (χ2 = 6:09, p = 0.7). The influx of nurses work resulted not affect the effectiveness of the service provided by nurses. ((Χ2 = 3.88, p = 0:02). Regarding the dimensions of health care delivery by nurses, only stigma and discrimination still proved to be an influential factor in their professional practice compared to the dimensions of biological, psychological, social and spiritual.

Conclusions: It is necessary continuing education of nurses on HIV-AIDS in disease treatment plan not only on the biological but also in the spiritual, social-family and within the psychological stigma reduction, discrimination etc. Patient education is also very important to change current perceptions regarding the best nursing care to improve the quality of the health service.


Majlinda ZAHAJ, Glodiana SINANAJ (Vlore, Albania), Brunilda SUBASHI, Rozeta LUCI, Denada SELFO, Brunilda MIFTARI
08:30 - 17:40 #11901 - Evaluation of drugs in effective pharmacological cardioversion in patients with or without previous atrial fibrillation.
Evaluation of drugs in effective pharmacological cardioversion in patients with or without previous atrial fibrillation.

Introduction

Atrial fibrillation (AF) is the most frequent sustained arrhythmia. It appears in all ages, being more frequent in the elderly. It is associated with an important morbimortalid in the form of stroke, thromboembolism and heart failure The treatment is focused on the prevention of the thromboembolic phenomena , control of the frequency and cardiac rhythm.

 Objective

To evaluate the drugs used in pharmacological cardioversion and its efficacy with reversion to sinus rhythm in patients with and without prior AF in the Emergency Department.

 Material and methods

Observational, retrospective study in a General Hospital with an area of 200,000 inhabitants and 275 urg / day. Patients diagnosed with discharge from AF who attended the ED between October 2012 and December 2013 were included. The pharmacological treatment and response rate of each drug used in effective pharmacological cardioversion were evaluated. For the analysis of data we used the statistical program SPSS 

Results

They consulted 762 patients for AF; 322 had previous diagnosis of AF and 442 did not.

322 with previous atrial fibrillation: rhythm control was performed in 110 (34.16%) with pharmacological cardioversion in 68 (61.8%).

The treatment was; Flecainide 39 (57.35%), Amiodarone in 27 (39.7%), Vernakalant 4 (5.9%) and Propafenone 0.

In 56 (82.35%) they were effective. The response rate of each drug was: Flecainide 33 (84.61%), Amiodarone 20 (74%), Vernakalant 4 (100%) and propafenone 0.

 

442 without prior atrial fibrillation: he controlled the rhythm to 89 (20.13%) with FVC in 58 (65.2%).

The treatment was: Flecainide 35 (60.34%), Amiodarone 21 (36.2%), Vernakalant 3 (5.17%) and Propafenone 0.

In 41 (70.7%) they were effective. The response rate of each drug was: Flecainide 27 (77.14%), Amiodarone 12 (57.4%), Vernakalant 3 (100%) and propafenone 0.

 Conclusions

Sinus rhythm cardioversion in the ED is performed in greater proportion to patients with previous atrial fibrillation.

Pharmacological cardioversion was performed proportionally similar in both groups, being higher in patients without prior AF and slightly more effective in patients with previous AF.

The choice of drugs is similar with greater use in both groups of Flecainide followed by Amiodarone and thirdly Vernakalant.

Flecainide followed by amiodarone appears to have a higher response rate in patients with prior atrial fibrillation. The response to Amiodarone is much worse in patients without prior AF. Vernakalant was used in third place, with a 100% response rate, although it was used in few patients.

 


Maria CORCOLES VERGARA, Fernandez-Camacho DANAE, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain), Jose Luis OTERO URIBE
08:30 - 17:40 #11902 - Evaluation of drugs in effective pharmacological cardioversion in patients with or without previous atrial fibrillation.
Evaluation of drugs in effective pharmacological cardioversion in patients with or without previous atrial fibrillation.

Introduction

Atrial fibrillation is the most frequent sustained arrhythmia. It appears in all ages, being more frequent in the elderly. It is associated with an important morbimortalid in the form of stroke, thromboembolism and heart failure The treatment is focused on the prevention of the thromboembolic phenomena , control of the frequency and cardiac rhythm.

Objective

To evaluate the drugs used in pharmacological cardioversion and its efficacy with reversion to sinus rhythm in patients with and without prior atrial fibrillation in the emergency department.

 Material and methods

Observational, retrospective study in a General Hospital with an area of 200,000 inhabitants and 275 urg / day. Patients diagnosed with discharge from AF who attended the emergency department between October 2012 and December 2013 were included. The pharmacological treatment and response rate of each drug used in effective pharmacological cardioversion were evaluated. For the analysis of data we used the statistical program SPSS 

Results

They consulted 762 patients for atrial fibrillation; 322 had previous diagnosis of Atrial fibrillation and 442 did not. 

322 with previous atrial fibrillation: rhythm control was performed in 110 (34.16%) with pharmacological cardioversion in 68 (61.8%).

The treatment was; Flecainide 39 (57.35%), Amiodarone in 27 (39.7%), Vernakalant 4 (5.9%) and Propafenone 0.

In 56 (82.35%) they were effective. The response rate of each drug was: Flecainide 33 (84.61%), Amiodarone 20 (74%), Vernakalant 4 (100%) and propafenone 0.

 

442 without prior atrial fibrillation: he controlled the rhythm to 89 (20.13%) with pharmacological cardioversion in 58 (65.2%).

The treatment was: Flecainide 35 (60.34%), Amiodarone 21 (36.2%), Vernakalant 3 (5.17%) and Propafenone 0.

In 41 (70.7%) they were effective. The response rate of each drug was: Flecainide 27 (77.14%), Amiodarone 12 (57.4%), Vernakalant 3 (100%) and propafenone 0.

 Conclusions

Sinus rhythm cardioversion in the emergency department is performed in greater proportion to patients with previous atrial fibrillation.

Pharmacological cardioversion was performed proportionally similar in both groups, being higher in patients without prior atrial fibrillation and slightly more effective in patients with previous atrial fibrillation.

The choice of drugs is similar with greater use in both groups of Flecainide followed by Amiodarone and thirdly Vernakalant.

Flecainide followed by amiodarone appears to have a higher response rate in patients with prior atrial fibrillation. The response to Amiodarone is much worse in patients without prior atrial fibrillation. Vernakalant was used in third place, with a 100% response rate, although it was used in few patients.

 


Maria CORCOLES VERGARA, Fernandez-Camacho DANAE, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain), Jose Luis OTERO URIBE
08:30 - 17:40 #11116 - Evaluation of emergency medicine dangers.
Evaluation of emergency medicine dangers.

The emergency departments are at risk for patients and caregivers. In cindynics, the overall assessment is to detect systemic, structural or organizational barriers that may endanger the organization: what are systemic deficits cindynogens (DSC). The purpose of the communication is to propose an evaluation of these DSC in an emergency department (ED).

Method : The search for DSC in the ED was approached under two angles: the look carried by each of the actors working in this ED with a questionnaire of self-assessment, and under the look carried by the supervisors who defined measurable criteria for every DSC. Every answer includes a 4 values Lickert scale. We were interested in the rates of positive answers and in the averages and the standard deviations.

Results : The rate of answer was equal to 72 %. The main deficits in the ED are the superiority of the productivist criteria ( DSC5), the attenuation of responsibility ( DSC6), the lack of procedures with cindynic dimension ( DSC8), a lack of knowledge in risk management ( DSC9) and a lack of preparation for crisis situations ( DSC10). There is almost no significant difference between the caregivers.

Discussion : There is a good acceptability of the questionnaire with an average rate of answer to every item equal to 93 %. The dispersal of the answers was moderated with an average absolved gap lower than 20 for eight DSC. The DSC being mainly a matter of the pole urgency without outside link was lowest, whereas those being a matter of external strong relations (for example the hospital administration) were the strongest. Corrective measures were implemented concerning experience feedback, trainings and protocols. A survey will be remotely made to estimate the impact on the DSC.


Philippe LEVEAU (THOUARS)
08:30 - 17:40 #11127 - Evaluation of geriatric emergency department admissions: two-year experience in a university hospital.
Evaluation of geriatric emergency department admissions: two-year experience in a university hospital.

Background: Patients aged 65 or older with multiple comorbidities constitute a significant part of the emergency department admissions in our country and all over the world. In different regions of our country, the geriatric emergency department admission rates were reported as 5% to 25% of all emergency admissions. In this study, we aimed to investigate the epidemiological features of patients aged 65 or older and admitted to emergency department with medical or traumatic reasons during two-year period.   

Methods: This retrospective observational study was conducted in the Emergency Department of Meram Faculty of Medicine. Patients aged 65 or older and admitted to our emergency department between June 15, 2014 and June 15, 2016 were included in the study. The following data were recorded: age, gender, major complaints, comorbidities, diagnosis, admission/discharge information, admission wards, length of stay in hospital, and in-hospital mortality. Patients were divided into three groups as 65 to 74-year-old group, 75 to 84-year-old group, and ≥85-year-old group. The differences of parameters between three age groups were also investigated.

Results: During the study period, there were 104,304 emergency department admissions in all age groups. 21,226 (20.4%) of them were patients aged 65 or older and included in the study. The mean age of the patients was 75.4±7.4 (65-107) years and 10,436 (49.2%) were male. 10,670 (50.3%) of the patients were in the 65 to 74-year-old group, 7,646 (36.0%) were in the 75 to 84-year-old group, and 2,910 (13.7%) were in the ≥85-year-old group. Approximately 10% of patients were admitted to emergency department in January and other admissions were equally distributed through the year. While 3,666 (17.3%) of patients were admitted to emergency department between 09:00 am and 11:59 am, 864 (4.1%) of patients were admitted between 03:00 am and 05:59 am. While 12.460 (58.7%) patients had been discharged from the emergency department, 8,766 (41.3%) patients were hospitalized at the wards or the intensive care units. The mean length of stay in hospital of patients was 7.3±10.0 days. The in-hospital mortality rate of all patients was 2.9%. While the in-hospital mortality rate was 4.9% in the ≥85-year-old group, it was 2.1% in the 65 to 74-year-old group.

Discussion: One-fifth of the emergency department patients were 65 years old or older. It is expected that the number of geriatric emergency patients will increase year by year due to prolonged average life expectancy and developing medical practice. Also, 40% of those geriatric patients are admitted to hospital and they have to stay in hospital about for a week. Our findings show that significant amount of time and money should be spent for medical care of geriatric emergency patients. Emergency physicians should be well trained in geriatric emergency medicine to provide best medical care and to make accurate risk-benefit and cost-benefit assessments.


Zerrin Defne DUNDAR (Konya, Turkey), Mustafa Kursat AYRANCI, Sedat KOCAK, Abdullah Sadik GIRISGIN, Basar CANDER
08:30 - 17:40 #11149 - Evaluation of infectious complications associated with central venous catheters: A moroccan intensive care experience.
Evaluation of infectious complications associated with central venous catheters: A moroccan intensive care experience.

Introduction

Central venous catheters are commonly used in inpatient care. Infection related catheter is the main complication and the second most common nosocomial cause in intensive care.

Material and methods

 This work is a retrospective, descriptive and analytical study of documented infections related to the central venous catheter, spread over a period of one year from January 2015 to December 2015 conducted in the medical resuscitation department.

 

Its objective is to determine the incidence, the microbiological profile the therapeutic modalities and the risk factors of central venous catheters ( CVC)infection.

It Included all the patients with central venous catheter infection (CVCI)with or without bacteraemia after hospitalization for medical resuscitation for more than 48 hours.

 Results

 The incidence rate was 6.78% with predominantly feminine51.9%

gram negative bacilli (BGN) were the most frequently isolated germs 40.5% with the highest incidence of acinetobacter baumanii and klebsiella pneumoniae at 26.6%, followed by cocci gram positive (CGPs 35.4% represented by staphylococcus coagulase negative (SCN) 84.6% Of the 27% with CVC infections 59.2% were deceased.

 It is important to note that the lack of information in the medical files concerning the installation of the CVC is a weighing element on the follow-up of its infections indeed a checklist must be used like a memo tool that will make it possible to minimize risks related to human hazard.

 Conclusion

 At the end of this work we conclude that the preventive measures based essentially on the strict observance of the rules of asepsis and the continuing training of the medical personnel on the new practices that can improve the prognosis of the CVC infections.


Ezzouine HANANE (CASABLANCA, Morocco), Abdelouafi TAREK, Nassiri GHASSAN, Hanzaz AMINE, Laasri KHALID, Benslama ABDELLATIF
08:30 - 17:40 #11115 - Evaluation of Patients Admitted to Emergency Department of Trakya University Health Center with Acute Pancreatitis Attack.
Evaluation of Patients Admitted to Emergency Department of Trakya University Health Center with Acute Pancreatitis Attack.

Acute pancreatitis is an important disease with high mortality and morbidity. The most common etiologic factors are; gallstones and alcohol use. Abdominal pain, elevated level of serum lipase enzyme and imaging findings are used in the diagnosis .

In our study parameters such as; demographic characteristics, etiological factors, anamnesis, complaints, physical examination findings, radiological imaging findings, laboratory parameters and Ranson - The Harmless Acute Pancreatitis Score (HAPS)scoring systems were used to evaluate the 3 month period of mortality rates of the patients.

The study was conducted retrospectively after the approval of the ethics committee with patients who admitted to the Emergency Department between May 1, 2013 and April 15, 2016. A total of 178 patients were included in the study, all of which had full information in their file.Patients were divided into 2 groups in terms of their mortality status within 3 months. These groups were named as Group 1 =Alive (n = 160) and Group 2 = Dead (n = 18). HAPS value was higher in the Group 2 compared to Group 1 and this was statistically significant. Also the parameters that indicate sepsis and septic shock were higher in Group 2.

 As a result of this study, we believe that; HAPS score and some parameters may be used in determining the short term mortality risk in acute pancreatitis patients. However, one of the limiting factors of our study was being single-centered and retrospective. 


Kemal YILDIZ, Ömer SALT (EDIRNE, Turkey), Mustafa SAYHAN
08:30 - 17:40 #11119 - Evaluatıon Of Relatıonshıp Between Inflammatory Markers And Severıty Of Hyperemesıs Gravıdarum In Early Pregnancy Patıents Admıtted To Emergency Department Wıth Nausea And Vomıtıng.
Evaluatıon Of Relatıonshıp Between Inflammatory Markers And Severıty Of Hyperemesıs Gravıdarum In Early Pregnancy Patıents Admıtted To Emergency Department Wıth Nausea And Vomıtıng.

Background:

Hyperemesis gravidarum (HG) is defined as severe nausesa and vomiting in early pregnancy and considered as one of the most frequentcauses to emergency department (ED) admissions.Previous research has shown that HG is associated with systemic inflammation, but none of them clarified the link with prospective method.The objective of this study was to assess the impact of systemic inflammatory response in patients with HG and to evaluate the association between severity of HG and levels of neutrophil lymphocyte ratio (NLR), platelet lymphocyte ratio(PLR) and CRP levels in patients who admitted to emergency department with nausea and vomiting.

Methods: This prospective study has been conducted in Kecioren Training and Research Hospital between 01.12.2015 - 01.05.2016.A total of 162 patients with <16 weeks old, singleton, healthy pregnancies and without any chronic diseases enrolled in the study.The study group consisted of 113 patients with HG and the control group included 49 healthy subjects. PUQE index and visual analog scale was used to evaluate the severity of symptoms.

Results:Demographical data were similar between both groups. The study group demonstrated significantly higher NLR and PLR levels (NLR 3.39 vs 2.5, p=0.001; PLR 134.3 vs 111.2, p=0.005). Also elevated CRP levels were found in the study group compared with control subjects (0.85 mg/dL vs 0.19 mg/dL, p=0.001).NLR and PLR levels were not significantly correlated with severity of HG (for NLR p=0.371, PLR p=0.967), while CRP levels were positively correlated with severity of disease (p=0.001) in case of patients divided to three subgroups using PUQE index.

Conclusion:NLR and PLR are easily obtained, unexpensive and routinely used diagnostic tools for several different diseases. Measurement of CRP, NLR and PLR levels might provide useful information in HG diagnosis. CRP is a better indicator for predicting severity of disease compared with NLR and PLR


Eda KAN, Emine EMEKTAR (Ankara, Turkey), Özgür KAN, Tuba SAFAK, Seref Kerem CORBACIOGLU, Yunsur CEVIK
08:30 - 17:40 #11537 - Evaluation of the diagnostic performance of the tunisian military SAMU.
Evaluation of the diagnostic performance of the tunisian military SAMU.

                                                                                                 Evaluation of the diagnostic performance of the tunisian military SAMU

 

Introduction:

The organization of the chain of care within the emergency medical assistance service (SAMU) calls upon two intervenient: the regulator and the emergency physician whose conditions of practice are quite specific. However, they are required to meet quality of care criteria.

This work was undertaken to validate diagnostic performance indicators and to be able to evaluate our activity in the military SAMU

 

Methods:

It is a prospective, descriptive and evaluative study carried out within the military emergency medical service over a period of 3 months, from September to December 2016. It compares the diagnostic decisions of the regulator and physician between them and with the definitive guidance service.

We have included all cases involving primary intervention with patient transport to a hospital structure. We excluded inter-hospital transfers, traumatic pathologies and patients left behind. We have collected 82 cases of regulatory cases and intervention files.

The reference diagnosis chosen is that of the recipient service.

 

Results:

The mean age was 49.9 years with a clear male predominance (72.5% of cases).

The reason for the call was unique in 83.7% of the cases. The regulator had a diagnosis, judged by him, confirmed in 15% of cases, and probable in 35% of cases. He made several diagnostic hypotheses in 17.5% of cases and remained symptomatic to explore in 32.5% of cases.

The intervention physician was found to have led to a confirmed or probable diagnosis in 70% of the cases and to several diagnostic hypotheses in 18.5% of the cases. The results of his diagnostic procedure were consistent with those of the regulator in 50% of the cases.

For the recipient service the final diagnosis, taken as a reference, was confirmed or probable in 87.5% of the cases. The most common pathologies were cardiac disease with 35.8% of cases, lung disease with 15% of cases, and neurological disease with 13.75% of cases.

The overall concordance rate of the diagnosis of the intervention physician with the referral service was 75% of cases with variations ranging from 85.71% of cases, for cardiac pathology, to 50% of cases for lung pathology. On the side of the regulator, the overall concordance rate with the referral service was 51.25% of cases with extremes ranging from 72.72% of cases, for neurological pathology, to 33.33% of cases for lung pathology.

CONCLUSION:

Diagnostic concordance is a good indicator of medical performance. The results obtained for the military emergency medical service are considered satisfactory according to the literature available on this subject.


Sonia SLIMI, Bassem CHATBRI (Tunis, Tunisia), Jihene KAROUIA, Mounir HAGUI, Monia CHIHAOUI, Mekki BEN SALAH
08:30 - 17:40 #11689 - Evaluation of the effect of improved qSOFA score on the severity and prognosis of emergency adult sepsis patients.
Evaluation of the effect of improved qSOFA score on the severity and prognosis of emergency adult sepsis patients.

Background

Because of the complexity of APAHCE II, SOFA score, their application is usually limited in the Emergency Department for rapid assessment and shunt. While qSOFA, MEWS, MEDS score is simple, but there are many shortcomings such as poor sensitivity or lack of predictive performance.

This study intends to find a tool(improved qSOFA score) for rapid assessment of the severity and prognosis of sepsis in the Emergency Department.

Methods

A retrospective study design, adult patients with sepsis enrolled between 00:00,July 1, 2015 to 23:59,June 30, 2016 in the Emergency Department of West China Hospital. Laboratory results within 24 hours of examination were collected, such as blood routine, biochemistry, DIC, blood gas analysis and PCT. These patients were divided into 2 groups according to the 28-day prognosis, the survival group and nonsurvival group. According to different infection system is divided into three subgroups. Calculate qSOFA, SOFA, APACHE II, MEDS, MEWS scores at admission.

Univariate analysis of risk factors for 28-day mortality in patients with sepsis at first, and then multivariate logistic regression analysis used to find an independent risk factor for 28-day mortality of sepsis. Draw an independent risk factor to predict the 28-day mortality rate of sepsis in the ROC curve, select AUC greater value combined with qSOFA score to create “Improved qSOFA score".

The efficacy of qSOFA scores, Improved qSOFA score, SOFA score, APACHE II score, MEDS score, and MEWS score was compared on predicting the 7-day mortality, 28-day mortality, 28-day mechanical ventilation, 28-day septic shock and 28-day ICU occupancy.

Results

1. Univariate analysis found that age, heart rate, respiration, peripheral oxygen saturation, LAC, oxygenation index, platelet count, hemoglobin, urea nitrogen, creatinine, albumin, fibrinogen, D-dimer, PCT effects of sepsis, the difference was statistically significant (p <0.05).

2. Multivariate logistic regression analysis showed that fibrinogen, plasma lactate, albumin, oxygenation index, and PCT were independent risk factors for 28-day mortality (p <0.05). The area under the curve (AUC) value of PCT is larger among them and with the sensitivity of 94.2%. When PCT> 0.5 ng / mL, the OR value is 10.928.

3. The improved qSOFA scoring system was established with PCT and qSOFA scores. The AUC of improved qSOFA for predicting 7-day and 28-day mortality, 28-day of septic shock, 28-day mechanical ventilation, 28-day ICU occupancy rate of patients with sepsis was larger than qSOFA score,MEDS score, MEWS score and the APACHE II score.

In conclusion

1. PCT as one of the inflammatory indicators is an independent risk factor for 28-day mortality of patients with sepsis.

2. The efficacy of improved qSOFA score had a good efficacy on Predicting the 7-day mortality, 28-day mortality, 28-day septic shock, 28-day mechanical ventilation, and 28-day ICU occupancy rates of adult patients with sepsis in Emergency Department.


Yiqin XIA, Yu CAO (Chengdu, China)
08:30 - 17:40 #11134 - Evaluation of the effectiveness of a specific training course aimed at the general public and provided by first aid professionals. Retrospective observational study.
Evaluation of the effectiveness of a specific training course aimed at the general public and provided by first aid professionals. Retrospective observational study.

Introduction: following the terrorist attacks in France in 2015, training of life-saving techniques (LST) was proposed to the general population. The main purpose of this work was to verify the effectiveness of this training in a group of civilian volunteers in urban areas trained by first-aid professionals. The second purpose was to characterize these participants.

 

Materials and Methods: retrospective observational study validated by an Ethics Committee, conducted by a proposed questionnaire to participants of an LST training of 2 hours (hemorrhage, standby position, detection of a cardiac arrest, external chest compression with an AED). Inclusion criteria: any participant over the age of 18 years having completed the questionnaire before/ after the training session, on epidemiological data and actions to be taken. Statistical Analysis: univariate description of the sample, comparison of type before/after for the variables "action to be taken". 

 

Results: from 01/16 to 06/30/2016, of 5,615 persons registered for LST training, 4,556 took part, 2,640 (100%) were included. The median age was 37 years IQR [30-47], with 1,744 (66%) women and 115 (4%) participants had been witnesses to a bomb attack in 2015. For 1,894 (72%) persons, this was their first training course of life-saving techniques. The number of right answers to questionnaires before (b)/after (a) and evaluation (e) of self-perception of actions to take face to were respectively: massive bleeding b.2032/a.2564/e.2582 out of the 2640; respiratory distress b.570/a.2421/e.2589; unconsciousness b.1016/a.1416/e.2397; several massive bleeding victims b.899/a.2500/e.2246; knowledge about their dispatch center b.1367/a.2226 and make chest compressions after instruction 2637/2640. The difference was significant between before/after for respiratory distress, unconsciousness, numerous massive bleeding victims and for knowledge about their dispatch center. 

Discussion : This LST allows teaching people how to administer first aid pending the arrival of the BLS team. This study highlights the progress felt by the participants.

Conclusion: We recommend the development of these LSTs which enable the resilience of the population to be reinforced.

 


Frédérique BRICHE, Olga MAURIN (Marseille), Fabian TESTA, Fabrice MARTIN, Thomas CHARMILLON, Gabriel PLUS, Denis DELCLOS, Michel BIGNAND, Jean-Pierre TOURTIER
08:30 - 17:40 #11438 - Evaluation of the management and the training of intra hospital cardiac arrest in emergency departments.
Evaluation of the management and the training of intra hospital cardiac arrest in emergency departments.

Introduction: Even though simulation is now widely used as a teaching and training technique, there is still a great difference between simulated cardiac arrest (CA) and real life complex cases of CA in an Emergency Department (ED). Many elements can complexify the management of CA. To this date, no study has evaluated the difficulties and the differences between the management of CA in EDs and in a simulation setting. The aim of this study was to identify difficulties in real life management of CA in order to include them in “realistic” simulation scenarios. 

Methods: We conducted a cross-sectional, anonymous, online survey on the use of simulation training and the difficulties associated with the management of cardiac arrest in real life. The survey of 32 items was distributed by email to 150 emergency physicians working in five EDs.  Descriptive statistics of percentage, mean and standard deviation were used to analyse the data.

Results: 43 answers were analysed (response rate of 31,3%). 53.7% were women with a median age of 31.5 years old (SD=2.7). 95% of the physicians had already participated in a simulation session with an affiliated simulation center in 58,5% of the cases. Only 14 had regular Cardio-Pulmonary Resuscitation (CPR) training using high fidelity simulation. According to the physicians, the elements that interfered with CPR were the non-medical personnel (35,7%) and overcrowding of the ED (28,6%). The most difficult step was intubation (36,8%), CPR organisation (26,3%) and intra venous catheter placement (18,4%). The difficulties in CPR were to coordinate the chest compressions (35,7%), to manage the non-medical personnel (21,4%) and to communicate (19%). On a scale of 0 to 10, the mean auto-satisfaction level on technical skills was 7,3, the mean satisfaction level of management skills as a team leader was 6,7 and the mean satisfaction level on communication skills was 6,83. The main differences between CA in simulation and in real life were overcrowding (34,2%), time management (18,4%), the noise (15,8%) and the intervention of other specialty physicians (15,8%). 66,7% answered that simulation had helped them in the management of CPR in real life. When asked what could improve the quality of CPR training in simulation, the analysis of qualitative answers shows the need for more “realistic” training sessions. The analysis of qualitative descriptive answers led to the creation of multiple “realistic” simulation scenarios.

Conclusion: This questionnaire study allowed a multi-centric evaluation of the difficulties encountered in real life cases of cardiac arrest in order to write very “realistic” simulation scenarios. The next step following this preliminary study will be to compare two different types of simulation training: traditional training and “realistic” training. This will answer the question of whether we should train like we work, and add more realism to our simulation training. 


Jennifer TRUCHOT (Paris), Daphnée MICHELET, David DRUMMOND, Anthony CHAUVIN, Antoine TESNIÈRES, Patrick PLAISANCE
08:30 - 17:40 #10483 - Evaporation of ammonium hydroxide intoxication: a case report.
Evaporation of ammonium hydroxide intoxication: a case report.

Objective: Ammonia is widely used in household and commercial cleaning agents, fertilizers and refrigerants. It is well known anhydrous ammonia poisoning induces inhalation injury, dysphagia, sore throat, or chemical burn . Nevertheless, it has rarely been reported that evaporation of ammonium hydroxide causes poisoning. We presented a case with an altered mental status (AMS) after staying at an airtight factory several minutes where a puddle of ammonium hydroxide was used.

Case report: A 40-year-old man was sent to our emergency department (ED) because of an altered mental status and acute respiratory failure. According to his colleagues, he wanted to find out a disappeared female, and therefore stayed at an airtight factory where ammonium hydroxide was used to counteract an unpleasant odor of a puddle of compounded oil on the ground. In the meanwhile, he initially smelled sour and then was found conscious disturbance with lying down several minutes later. He was intubated in the first hospital and transferred to our ED. His vital signs on arrival were [i] blood pressure: 100/68 mmHg, [ii] heart rate: 87 beats/minute, [iii] body temperature: 36℃, and [iv] Glasgow coma score: E1VEM4. Physical examination revealed rales breathing sound, yet no chemical burn over skin, oral or nasal mucosa. His consciousness totally improved one day after hospitalization and was extubated 2 days later. He regularly followed up without any sequela of ammonia intoxication. Unfortunately, the female died at the factory and the autopsy report confirmed the cause of her death was ammonia intoxication- related acute respiratory failure.

Conclusion: There are very few reports that evaporation of a small puddle of ammonium hydroxide could induce patient respiratory failure and an altered mental status. Our patient presented with some classic signs of ammonia intoxication, for example, acute respiratory failure and conscious disturbance, but he didn’t have skin or mucous lesion. Although there is no direct evidence to prove our case poisoning with ammonia, the circumstance at the moment and autopsy report of the female are related to ammonia. Factory employees and cleaners should be more notice the hazard of ammonium hydroxide and avoid using it in airtight condition.         


Hon Pheng TAM (Liouying, Tainan, Malaysia), Chien-Chin HSU, Tsung-Hang KUO, Hung-Sheng HUANG
08:30 - 17:40 #11386 - Evolution of early presenters with ST elevation myocardial infarction according to their location (town and suburb) and the time of symptoms onset.
Evolution of early presenters with ST elevation myocardial infarction according to their location (town and suburb) and the time of symptoms onset.

Introduction: Quick coronary reperfusion is a major prognosis factor of ST-segment elevation myocardial infarction (STEMI). Reperfusion strategy has a greater effect for the early presenters (EP), patients whom are seen with less than 2 hours between chest pain onset and first medical contact (FMC).

Aim: Evaluate the evolution of EP with STEMI according to their location (town and suburb) and the time of symptoms onset.

Materials and methods: Data derived from a prospective register including STEMI < 24h managed by 8 prehospital emergency medical services and 39 medical care intensive units (MCIU) of a French city. Inclusion criteria were patients with STEMI of less than 2 hours between 2003 and 2015. Exclusion criteria were interhospital transfers. Different area were defined: inner city (IC), inner suburb (IS) and outer suburb (OS). Linear regression analysis and student test were used for testing the trends (statistical significance p < 0.05).

Results: 13071 EP were included (IC=2409, IS=4187 and OS=6475) and accounted 62% of all STEMI. Their distribution varied significantly according to geographical area IC = 60%, IS = 61% and OS = 65% (p < 0.0001). Between 2003 and 2015, the rate of EP increased in the region (p = 0.0017). By area, this increase was confirmed, only significantly for OS (p = 0.0221).

Conclusion: There is a clear time saving in management of EP STEMI patients mainly when living in outer suburb.


Alexandre ALLONNEAU, Hugues LEFORT, Aurélie LOYEAU, Isabelle KLEIN, Dr Abdo KHOURY (Besançon), Benoît SIMON, Thévy BOCHE, François DUPAS, Jean-Michel JULIARD, Sophie BATAILLE, Frédéric LAPOSTOLLE, Yves LAMBERT
08:30 - 17:40 #11327 - Evolution of management of children with sickle cell disease (scd) in the paediatric emergency department (ed) in padova.
Evolution of management of children with sickle cell disease (scd) in the paediatric emergency department (ed) in padova.

SCD is a chronic multisystem disease characterized by haemolytic anaemia, susceptibility to infection and vase-occlusive pain crisis. The increasing number of children with SCD in Europe requires pediatric hematologist to change their education and training. In Italy national guidelines were published in 2012 giving recommendations and ensuring high quality care for all SCD patients. Several studies in Europe and US revealed an inadequate management of acute complications of SCD children who access the ED. The first aim of this study is to describe the extent and the characteristics of ED access by SCD patients in our area. Secondly, this study evaluated the diagnostic-therapeutic pathway utilized by ED personnel in SCD patients accessing a paediatric ED and determined the impact of these interventions on health care behaviours. This is a retrospective study which has involved SCD patients taken in care by the Clinic of Paediatric Haematology-Oncology of Padova Hospital and admitted to the ED of Padova Hospital from January 2006 to July 2015. The Clinic of Pediatric Hematology-Oncology of Padova is part of a tertiary teaching hospital and started to take care of  patients with SCD in 2003. Since 2009 a series of educational events were proposed on the acute management of SCD. Sixty-six patients with SCD were admitted to the ED from January 2006 to July 2015. They accounted for 393 ED accesses. The main reasons of access to the ED were: pain(35%) and fever(21%). A high-priority triage level was assigned to 63% of the admissions. Considering SCD patients who accessed the ED for fever, the body temperature was taken in 97% of visits and blood culture were performed in 84%. The antipyretic was administered in 66% of episodes and the antibiotic was administered in 72% of episodes. Considering patients who accessed for pain, the Visual Analogue Scale (VAS) was used in 63% of ED accesses. The analgesic was administered in 72% of cases but only in 26% of cases within 30 minutes. During the medical history,information on vaccinations was recorded in 16% of cases. Comparison of SCD patients’ management in 2010-2015 versus 2006-2009, showed an increased number of accesses and an increased attribution of high score at triage (48% vs 70%, p=0,0002). Among the most relevant improvement we discussed: VAS score use (13% vs 71%, p<0,0001), the use of analgesic (59% vs 77%, p= 0,0122) and more precise management of the medical history. We confirm the usefulness of educational events and we propose multimodal repeated interventions as a way to successfully introduce guidelines into clinical practice. We should find efficient strategies and specific interventions to spread and reinforce the messages delivered in the educational events focusing on the major areas of concern: the administration of the analgesic within 30 minutes from admission of children with pain, the increase of the number of blood culture and antibiotics administration in all patients with T≥38°C.


Chiara MARRA, Liviana DA DALT, Raffaella COLOMBATTI, Laura SAINATI, Silvia BRESSAN (Padova, Italy)
08:30 - 17:40 #11555 - Examination of nasal high flow in type II respiratory failure cases in our hospital.
Examination of nasal high flow in type II respiratory failure cases in our hospital.

Background:

Type II respiratory insufficiency that causes hypercapnia is often experienced clinically and is often derived from hypoventilation. Although positive pressure ventilation such as invasive positive pressure ventilation (IPPV) or noninvasive positive pressure ventilation (NPPV) is frequently selected for the purpose of increasing the amount of ventilation, there are few reports showing the effectiveness of nasal high flow (NHF) in type II respiratory failure. This time we investigated retrospectively for patients who select NHF in the withdrawal process from IPPV or NPPV in cases of type Ⅱ respiratory failure.

Patients and methods:

Twelve patients who were admitted to our emergency and critical care center from May 1, 2016 to April 31, 2017 were targeted. We examined sex, age, outcome, disease and average PaCO2 under control by IPPV, NPPV and NHF.

Result:

The ratio of males and females was 4: 8, the average age was 79.9 years, the survival discharge was 7 cases, and the death discharge was 6 cases. Diseases were 5 cases of diffuse lung disease (interstitial pneumonia, COPD), 2 cases of respiratory infection, 2 cases of chronic heart failure, 1 case of neuromuscular disease, 2 cases in the other cases. There were 7 cases of switching from NPPV and 5 cases of switching from IPPV. Regarding PaCO2, there was no significant difference in average value between IPPV and NHF management, NPPV and NHF management respectively.

Discussion:

Many cases were suspected of hypoventilation resulting from a decrease in pulmonary compliance. Wash out of the dead space has been pointed out as an effect of NHF, and this effect seems to have contributed to the prevention of an increase in carbon dioxide concentration without excessive positive pressure. On the other hand, death cases are often derived from airway problems such as asphyxia and aspiration, and the prognosis improvement effect of cases with airway problems is considered to be poor.

Conclusion:

In Type II respiratory insufficiency cases, it was shown that NHF could be administered without exacerbation of hypercapnia, in withdrawal from IPPV or NPPV.


Keitarou SUZUKI (Osaka, Japan), Masahiro SHINOZAKI, Arito KAJI, Hiromasa YAKUSHIJI, Motohiro YAMADA, Wataru SHIRASAKA
08:30 - 17:40 #11274 - Experiences of Integrating Low and Medium Fidelity Simulation in Emergency Medicine Didactic Teaching Programs.
Experiences of Integrating Low and Medium Fidelity Simulation in Emergency Medicine Didactic Teaching Programs.

Background

High fidelity simulation is associated with significant costs with time, facilities and resources. In this descriptive case study, we describe our experiences of integrating low and medium fidelity simulation within the weekly didactic sessions of Emergency Medicine (EM) training programs in Qatar. This simulation strategy was adapted for an EM fellowship program with 49 fellows and a bridging program known as the consolidation program with 20 middle grade physicians over a period of 12 to 24 months. We decided on this strategy in order to improve the overall educational experience of our learners and facilitate formative assessments in a simulated setting, specifically in patient safety related competencies such as airway management, sedation and other clinical skills.

Methods

We deployed freely available software program known as “the vital signs simulator” for the PC and a relatively inexpensive program called “iSIM” for the iOS platforms, the only requirement being the availability of a second projecting screen in the form of an additional PC monitor or an IPad. We purchased the Laerdal© 2G resuscitation manikin and Laerdal© airway management trainer and borrowed smaller equipment such as the airway trolley, laryngoscopes, and others as required from the clinical areas. 

The primary focus of training was on the acquisition of clinical skills and critical thinking in clinical scenarios. We later successfully incorporated human factors training on team working, leadership and closed loop communication. The simulation scenarios were based on simple and complex sequential case narratives with built-in scenario debriefing, formative feedback and evaluation of performance. The faculty physicians were senior consultants in EM with previous experience of undertaking simulation as advanced life support course instructors. They were offered brief orientations to the software, the use of manikins, the scenarios and the formative assessment tools, but did not receive any other specific training.

Results

In terms of feasibility, we achieved significant savings in resources and time. Continuous evaluation of the sessions revealed positive feedback from both the fellows and faculty with better engagement during teaching sessions. The fellows valued the educational experience and were supportive of more such sessions in their weekly didactics. In spite of the low, medium fidelity of the simulation, fellows felt there was better alignment with real life clinical practice with resultant overall awareness of the importance of team working and effective communication.

Conclusions

We recommend the integration of low and medium fidelity simulation in weekly emergency medicine training sessions to address clinical skills acquisition and human factor issues. There are possible significant efficiencies in resource and faculty time that could be achieved with this strategy.

All authors declare no conflict of interest with manufacturers named in the abstract.


Saleem FAROOK (Doha, United Kingdom), Ayman HEREIZ, Khalid BASHIR, Ashid KODUMAYIL, Thirumoothy Suresh KUMAR
08:30 - 17:40 #11923 - Exploring a clinical tool for predicting mortality in symptomatic atrial fibrillation.
Exploring a clinical tool for predicting mortality in symptomatic atrial fibrillation.

Introduction:

Atrial fibrillation leads to frequent visits to the emergency department (ED) with estimated visits of 1%. Clinical decision making and therapeutic issues are heterogenous worldwide. This situation can furthermore be life-threatening and may lead to an increase rate of hospitalizations. In this context, an accurate estimation and stratification of the risk seems to be necessary. A clinical prediction tool was recently proposed to estimate the risk of 30-Day adverse events in the ED for patients admitted for symptomatic atrial fibrillation( RED-AF score).The aim of this study was to explore the prognostic value of this score in our population in terms of mortality.

Methodology:

This was a single-center prospective study over 1-year  with inclusion of all adults patients visiting the ED and in wich the diagnosis of symptomatic atrial fibrillation was made. Prognosis scores were calculated. The RED-AF score was also calculated using clinical tool. ROC curve were established. Mortality  at day 30 and  was analyzed.

Results:

Inclusion of 123 visits for symptomatic atrial fibrillation. Average age = 62 +/- 15 years. Sex-ratio = 0,78. Clinical characteristics and prognostic scores (mean , SD) : Systolic blood pressure  [mmHg ( 128, 26)]; heart rate [bpm (148,29)]; CHA2DS2VAsc (2,42-1,96 ); HASBLED (1,71-1). Mortality at day 30 : n(%) = 14 (11); recurrent ED visit at day 30 24 (19,5). The  mean RED-AF score = 125 +/- 41. RED-AF score was higher in non survivors than in survivors ; p < 0,001. ROC curve’s characteristics of the RED-AF score in predicting mortality are :  AUC = 0,715; CI 95% [0,533-0,835]; p < 0,001: cut-off value >=  110; sensitivity = 93% ; negative predictive value = 98%.

Conclusion :

Atrial fibrillation is a serious condition with high morbid-mortality and need to hospitalization. The need of clinical tools predicting with accuracy the adverse events and the prognosis are necessary to evaluate and to adapt to the emergency physician. In this cohort RED-AF score seemed to be accurately predictive for mortality at day 30. Exploring the other drug adverse events are however a cornerstone to validate this score in our population.


Bahria WIDED (tunisie, Tunisia), Hamed RYM, Badra BAHRI, Maroua MABROUK, Wided DEROUICHE, Houda NASRI, Rym HAMMAMI, Chokri HAMOUDA
08:30 - 17:40 #11919 - Extensive burns from electronic cigarette (e-cigarette) battery explosion.
Extensive burns from electronic cigarette (e-cigarette) battery explosion.

Electronic cigarettes (e-cigarettes) are now increasingly used as an alternative to smoking. E-cigarrette was first invented in China in 2003 and since then the use of it has steadily increased. Along with other vapourisers, it is classified as Electronic Nicotine Delivery System (ENDS). Globally the vapour device business has grown in an excess of £7 billion. E-cigarettes are made up of an aerosol generator, a flow sensor, a battery, and a solution storage area. The battery is made up of Lithium Ion and when it gets overheated, it can explode and could cause serious burns by a mechanism called thermal runaway. The solution used is called e-liquid and is made up of nicotine, flavors, glycerol and propylene glycol.

A 49 year old gentleman was at work keeping his e-cigarette in his trouser pocket when it exploded. His trouser was completely destroyed and he sustained burns to his right hand and right thigh. His entire right hand palm sustained 1st degree burns. He also sustained a mix of first, second and third degree burns of the front, side and back of the right thigh. The thigh burn was not circumferential and there were no involvement of the genitals. He works as a lorry driver and was luckily not driving at that time. His co-worker helped him to get the device out of his trouser.

Many users do not understand the risk of “thermal runaway,” whereby internal battery overheating causes a battery fire or explosion. The can happen even when the device is not on charging. This gentleman was referred to our burns and plastics team.

There are three type of injuries identified with e-cigarette explosion. They are flame burns, chemical burns and blast injuries. Any pat of the body can be affected, however the most commony affected part were groin and thighs. The literature shows that blast injuries have led to tooth loss, traumatic tattooing, and extensive loss of soft tissue, that may require operative debridement and closure of tissue defects. The flame-burn injuries requires extensive wound care and skin grafting, and exposure to the alkali chemicals released from the battery explosion can cause chemical skin burns and require wound care. So far no deaths have been reported. 

E-cigarettes remain largely unregulated. 

Brownson E, Thompson C et al. Explosion Injuries from E-Cigarettes. N Engl J Med 2016; 375:1400-1402 October 6, 2016 DOI: 10.1056/NEJMc1608478


Suresh PILLAI, Nisha MALLYA (Swansea, United Kingdom), Napolean LORIN
08:30 - 17:40 #10745 - EXTENSIVE SUBCUTANEOUS EMPHYSEMA ASSOCIATED WITH CHEST TUBE INSERTION IN A COPD PATIENT: A Case report.
EXTENSIVE SUBCUTANEOUS EMPHYSEMA ASSOCIATED WITH CHEST TUBE INSERTION IN A COPD PATIENT: A Case report.

Abstract:

Subcutaneous emphysema may complicate a pneumothorax, but may also occur as a consequence of its treatment by chest tube drainage. This patient in his 80s presented with a localized left sided pneumothorax on a background of chronic obstructive pulmonary disease (COPD) with some features of a Tension pneumothorax on presentation at our Emergency Department . This was initially treated with a left axillary Needle thoracostomy, followed by a formal intra-pleural chest tube insertion. However, after insertion of this tube, the patient developed subcutaneous emphysema, which later progressed extensively despite the Chest Tube functioning well upon insertion. Subsequently, further intra-pleural chest drains on negative pressure suction  with removal of the initial chest tube were required. Patient ultimately required endotracheal intubation and medical intensive care unit(MICU) admission due to persistent desaturation. Patient improved subsequently in MICU after another chest tube insertion and was extubated after a trial of extubation. Patient also developed severe deconditioning during his hospital stay, needing extensive rehabilitation measures. 


Abhay KANT (Singapore, Singapore)
08:30 - 17:40 #11363 - Extrapyramidal Side Effects of Metoclopramide: Nothing Beats a Good History.
Extrapyramidal Side Effects of Metoclopramide: Nothing Beats a Good History.

INTRODUCTION

A 62year old female patient with a background of bowel cancer on chemotherapy presented to the Emergency Department(ED) with an acute history of lip puckering, difficulty speaking, dry mouth, facial spasm and twitching and a tingling sensation in her fingertips. She routinely took a 10mg Metoclopramide tablet before her chemotherapy tablets at 09h30 every morning. 3 hours later she reported feeling strange. She thought the symptoms were due to her chemotherapy so she took another 10mg Metoclopramide tablet at 14h30. Her symptoms got worse. Her daughter noticed the facial droop and called her general practitioner who referred her to the ED to out rule a transient ischemic attack(TIA). She had no other focal neurological or associated symptoms.

 

TREATMENT

On examination the patient had lip puckering and a swollen lower lip with difficulty speaking. Her neurological examination was otherwise normal. Her vital signs including her blood glucose were normal. After a detailed history and examination, it was suspected that she had extrapyramidal side effects or a hypersensitivity to Maxalon. Her symptoms did not resolve after initially given Chlorphenamine and Hydrocortisone. Procyclidine 5mg was given to her a short time later and subsequently her symptoms resolved completely.

 

DICUSSION

 

Metoclopramide (a chlorobenzamide) is a useful antiemetic and has prokinetics effects. Extrapyramidal side effects occur in about 0.2% of cases but can increase up to as high as 25%. (1) These effects present usually with the first 24 -72 hours post administration and sometimes as soon as 10-15 minutes later (2). Parkinsonism, Tardive dyskinesia, oculogyric crisis, akathisia and acute dystonia’s are often seen. The side effects are often misdiagnosed; mistreated and over investigated. Symptoms tend to resolve rapidly and without serious sequela after the cessation or reduction of the causative drugs. Drug knowledge, awareness of side effects and a good history often allude to the correct diagnosis.


Muhammad Zeeshan AZHAR (Barrow in Furness, United Kingdom), Kiren GOVENDER
08:30 - 17:40 #11391 - Extreme hypernatremia (195 mmol/L): A case report.
Extreme hypernatremia (195 mmol/L): A case report.

Background: Hypernatremia is a serum sodium concentration >145 mmol/L. When this level exceeds 160 mmol/L, it is called severe hypernatremia while the concentration above 190 mmol/L is extreme hypernatremia and associated with high mortality. The main cause of hypernatremia is lack of fluid intake or excessive fluid lost from the body. It is usually observed in immobile patients, neonates, infants, elderly, or those with neurological problems.

Case: A 25-year-old male patient who was immobile due to cerebral palsy admitted to emergency department because of high fever and altered consciousness. His medical history revealed 10 days of impaired oral intake and 3 days of fever and altered cognitive functions. His general appearence was worse, his conscious was confused with no orientation and co-operation, his eyeballs were collapsed and oropharynx and mucous membranes had a dry appearance in his pyhsical examination with abnormal vitals; fever: 37.9 ºC, pulse:106 /min, respiration: 28 /min, BP:93/52 mmHg. In the laboratory tests; BUN: 119 mg/dL, Kr: 1.4 mg/dL, Na: 195 mmol/L, Cl: 154 mmol/L, K: 2.8 mmol/L, Ca (corrected): 9.2 mg/dL, Mg: 2.47 mg/dl. Cranial imaging revealed diffuse cerebral cortical atrophy and consequent enlargement of the sulcus and ventricles, no additional pathology or bleeding was reported. The patient was admitted to intensive care unit with a diagnosis of mortal electrolyte impairment. The patient was discharged on the 11th day of admission after his serum sodium level was lowered up to 139 mmol/L during his follow-up. 

Discussion: Hypernatremia is frequently seen in infants, elderly, and any patients with impaired consciousness who has impaired thirst and/or restricted access to water (4). Hypernatremia is divided into two according to the time of onset: acute and chronic. Clinical symptoms vary depending on the level of hypernatremia. Nonspecific CNS findings, nausea, vomiting, muscle weakness, restlessness, irritability, all levels of cognitive function impairment, nystagmus, seizures, myoclonic contractions and death are can be seen. There is a correlation between the level of consciousness and the level of serum sodium. Brain shrinkage may result in vascular tearing complications and intracranial hemorrhages in the case of sodium levels exceeding 160 mmol/L. During extreme hypernatremia phase, sinus tachycardia, decrease amplitude of P wave and QRS complex, short PR interval, prolonged QT and diffuse ST depression may occur in ECG. The aim of the treatment is to replace fluid lost and to correct hypernatremia gradually. The decreasement rate of sudium in chronic hypernatremia is 10-12 mmol in 24 hours.

Conclusion: Although extreme hypernatremia is less common than other electrolyte disorders, clinicians should be careful because of both extremely high sodium levels and complications that may develop during correction of high sodium levels.


Oğuz EROĞLU, Sevilay VURAL, Ömer YESILYURT, Barış YILMAZ, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #11328 - Facebook group enhances emergency medicine residents networking and information sharing between small training programs.
Facebook group enhances emergency medicine residents networking and information sharing between small training programs.

Background:

Emergency Medicine (EM) was recognized as the 23rd medical specialty in 1997 in Taiwan. There are 97 residents in 39 training programs in 2016. Twenty-five programs (64%) have only 2 or 3 new residents every year. The networking, collaboration, and resources sharing between EM residents in small training programs were difficult. We started a Facebook group “Emergency Medicine Resident Network, (EMRN)” (https://www.facebook.com/groups/1055763321109570/ ) in December 5, 2015 trying to cope with this challenge. This study aims to evaluate the performance and impact of a Facebook group on EM residents networking.

Methods:

Design: This study was an observational study.

Setting: All of the data were collected from Facebook group “EMRN”.

Type of participants: All of the posts, comments, likes, number of members and activities were enrolled.

Data Collection: The statistics were retrieved on November 20, 2016.

Data Analysis: The demographic data were analyzed by descriptive statistics.

Results:

A total of 1585 members joined EMRN till November 2016. The activities of EMRN were constituted of three parts: daily posts sharing, theme activities, and face to face networking events. There were 840 posts, 1085 comments, 326 comments to comments, and 18925 likes in the first year. There were average 2.3 posts and 4 comments, and 52 likes every day. Two theme activities were organized which focused on sharing experience to young attending physicians and first year residents. Senior EM physicians were invited to share their experience on these topics. Those invited posts were the top 10 most highly liked post in EMRN. Face to face networking events are still critical to establish connections. The first events was held in the annual conference of Taiwan Society of Emergency Medicine in June 2016.The second events was held in the U.S. during ACEP scientific assembly 2016 targeting on interviewing with the President of Emergency Medicine Residents’ Association. The video recording was shared via YouTube (https://youtu.be/obCPUWz8kRs ).

Conclusions:

Social media is a quick and efficient way to enhance networking between EM residents in small training programs. Organized theme activity can attract more attention from group members, making information and experience sharing easier. EMRN project provided an model for small-scale EM resident training programs to connect residents, enhance efficiency by the help of social media.


Ching-Hsing LEE, Chen-Mei HSU, Hao-Yang LIN, Pei-Chen JUAN (Taoyuan, Taiwan)
08:30 - 17:40 #11024 - Facing thoracic pain in the youngest population.
Facing thoracic pain in the youngest population.

     Nowadays, the presentations in the emergency department of the young population is increasing considerably.Although most patients in this age group will be sent home with recommendations and treatment after clinical examination and paraclinical investigation, as nedeed, sometimes we can deal with real ''surprises''.

     This is what happened in this case-report, that of a young patient, male, aged 19 years, brought to the Emergency Department of Targu Mures, Romania,by transfer from a territorial hospital.The patient presented with chest pain, for about 1.5 hours, with spontaneous resolution which occured 48 hours prior addmision.The  pain reappear at rest, has longer extent, is associated with fattigue, and it improves after drugs.The patient is a chronic smoker, he denies previous medical history and chronic treatment.Physical examination is normal and shows a patient with a relatively good general condition, AV=60 beats/min, BP=150/80 mmHg.

Laboratory examinations performed at the teritorial hospital revealed: ECG inferior ST elevation in DII, DIII, aVF; positive troponin (10.8 ng/ml) and CK (911 U/L).Repeated laboratory examinations on arrival in the ED of Targu Mures were as follows: ECG- sinusal rhythm, AV = 98 beats/min,  1mm ST segment elevation in D II, D III, aVF; positive troponin=10.9 ng/ml and CK-MB=148 ng/ml.

A cardiology consultation was performed for the pacient  and the echocardigraphy detected an inomogenous echostructure of the interventricular septum suggestive of myocarditis, decreased left ventricular contractility, hypokinesia more pronounced in the SIV, minor mitral and tricuspid valve regurgitation.

The patient was addmited in the coronary intensive care unit and during hospitalization a coronary angiography was performed, in terms of effective anticoagulation and double antiplatelet therapy.The result is as follows: left coronary artery trunk and anterior descending artery without angiographically significant lesions;right coronary artery without angiographically significant lesions, persistence of contrast in the vertical segment. Optical coherence tomography examination of the heart showed adventitial inflammatory infiltrates of lymphocytes to the vertical segment of the right coronary artery, without narrowing it.This aspect, added to the one that suggest  the inomogenous echostructure of the interventricular septum, suggest a diagnosis of myocarditis.

Receving antiplatelet drug therapy, beta blockers, ACE inhibitors, the patient shows favorable evolution without recurrence of symptoms. He was discharged electrically  and hemodynamically stable, with recovery and treatment plan.In conclusion, chest pain approach should be done in the same way, whether we are dealing with a population segment in which the  cardiac complaints are rare. Thus, using algorithms should guide us in medical judgment, investigations and treatment for the management of patients with chest pain.


Pavel FLORINA (Targu Mures, Romania), Salanta MARIA, Mates OANA
08:30 - 17:40 #11131 - Factitious Hypoglycemia.
Factitious Hypoglycemia.

Objetive: Early Diagnosis of Factitious Hypoglycemia due to the relation whith Personality Disorders, Depression and Suicide.

Method: 
A 31-year-old patient who came to the emergency department for a sustained hypoglycaemia of 48 hours. Similar table previous years without definitive study. In the clinical history, the patient refers to obesity due to treatment with Corticosteroids by respiratory pathology 3 years ago, with which she was diagnosed with Diabetes Mellitus and treated with oral antidiabetics. At the moment denies any treatment. During her admission, the patient did not present episodes of hypoglycemia. Clinical examination is normal. During her stay, a consultation with an Endocrinology service is requested, which keeps the patient without a serum test to check glycemic numbers. Determination of Sulphonylureas, which give Glibenclamide positivity is requested. Insulin (74.37 μU / ml), Peptide C (9.16 ng / ml). Insulin / peptides C: 8.11 (> 1)

Results: Factitious hypoglycemia due to consumption of Glibenclamide. The patient is referred to psychiatry for study and follow-up

Discussion:  Factitious (or factitial) hypoglycemia occurs secondary to the surreptitious use of insulin or insulin secretagogues (sulfonylureas, meglitinides). The term factitious (or factitial) hypoglycemia has been used in medical parlance to imply covert human activity. The consideration of such a possibility often changes the patient-clinician relationship, leading the clinician to feel deceived and the patient to feel mistrusted. Nondiabetic subjects with factitious hypoglycemia can present with a clinical syndrome that appears similar to insulinoma; as a result, many of them have undergone futile abdominal exploration and needless subtotal pancreatectomy in search of an insulinoma. The appropriate application and interpretation of available tests will preclude surgical exploration in them. The premature detection makes easy the early psychological attention of the patient and prevents the exposure to actions implying risk for life or permanent damage.


Rocio RODRIGUEZ BARRIOS (MALAGA, Spain), Rocio BORDALLO ARAGON, Ana PEREZ TORNERO
08:30 - 17:40 #11688 - Factors affecting the delay for time of emergency department admission in patients with acute stroke.
Factors affecting the delay for time of emergency department admission in patients with acute stroke.

Introduction: Acute ischemic Stroke is a frequent neurovascular emergency. It is the second most common cause of death and the first leading cause of disability in developed and developing countries. We must act on all the factors influencing the different stages from recognition until the end of the treatment to improve the prognosis of this pathology.

 

Objective: To analyze the factors that delay emergency department (ED) visit in patients presenting an acute stroke. 
Methods:

Prospective, monocentric, observational study conducted over four years. Inclusion: patient (age ≥ 18 years) with neurological signs suggestive of acute stroke. Report of socio-demographic, epidemiological, clinical and scanner criteria. Stroke severity was evaluated with the National Institutes of Health Stroke Scale (NIHSS). Two groups were identified depending on the time between the appearance of functional signs and emergency department visit: Group (time > 3 hours (h)), Group (time ≤3h). Univariate and multivariate analysis by multiple logistic regression to identify factors influencing the admission period.

Results:

Inclusion of 218 patients. Mean age = 66 ± 14 years. Sex ratio = 1.5. Group (time > 3h): n = 87(40%), Group (time ≤ 3 hours): n = 131(60%). Cardiovascular risk factors (%): hypertension (64), diabetes (34), history of stroke (28), atrial fibrillation (12). Ischemic Stroke: 70% of cases. Average NIHSS = 8 ± 6. Average Glasgow coma scale (CGS) = 13 ± 2. Univariate analysis identified age of patient > 70 years, history of stroke, absence of facial involvement, systolic blood pressure (SBP <147 mmHg and diastolic blood pressure (DBP) < 82mmHg as significantly related to a time >3 hours. In multivariate analysis :history of stroke ( adjusted OR = 1.54 , 95% CI [ 1.13-2.11] , p = 0.006), absence of face involvement( adjusted OR = 1,48 , 95% CI [ 0.5 – 0?91 ] , p = 0.01 ) and history of coronaropathy (adjusted OR=.70, 95%CI [0.359-0.966], p=0.036) was independently associated with an admission period > 3h.

Conclusion:

History of stroke or coronaropathy and absence of facial involvement were independently associated with admission time >3h.     


Hanen GHAZALI (Ben Arous, Tunisia), Manel KALLEL, Mouna GAMMOUDI, Anware YAHMADI, Morsi ELLOUZ, Mahbouba CHKIR, Monia NGACH, Sami SOUISSI
08:30 - 17:40 #11249 - Factors Associated with Acute Kidney Injury in Multiple Trauma Patients with Rhabdomyolysis.
Factors Associated with Acute Kidney Injury in Multiple Trauma Patients with Rhabdomyolysis.

Introduction

Rhabdomyolysis is a syndrome characterized by muscle necrosis and the release of intracellular muscle constituents into the circulation. Acute kidney injury is a potential complication of severe rhabdomyolysis and the prognosis is substantially worse if renal failure develops. We try to identify the factors that were predictive of AKI in severe trauma patients with rhabdomyolysis.

 

Methods

This retrospective study was conducted at the emergency department of a level Ⅰ trauma center. Patients enrolled that initial creatine phosphokinase (CPK) levels were higher than 1000 IU with acute multiple trauma, and more than 18 years older from Oct. 2012 to June 2016. We collected demographic data (age, gender, length of hospital day, and patients’ outcome), laboratory data (ABGA, lactate, hemoglobin. hematocrit, platelet, LDH, myoglobin, liver enzyme, and BUN/Cr), and clinical data (Injury Mechanism, RTS, ISS, AIS, and TRISS). The data were compared and analyzed between AKI and Non-AKI group. Statistical analysis were performed using IMB SPSS 20.0 statistics for Window.

 

Results

Three hundred sixty-four patients were enrolled that AKI group were ninety-six and non-AKI group were two hundred sixty-eight. The base excess (HCO3), AST/ALT, LDH, and myoglobin in AKI group were significantly higher than non-AKI group from laboratory data (p 0.05). The injury severity score (ISS), revised Trauma Score (RTS), Abbreviated Injury Scale 3 and 4 (AIS 3 and 4) were showed significant results in clinical data. The patterns of CPK level were increased from first and second day, but slightly decreased from third day in both group. Seven patients had received hemodialysis treatment despite the bleeding risk and were survived in AKI group.

 

Conclusion

We recommend that HCO3, CPK, LDH, and myoglobin should be checked and be concerned about ISS, RTS, AIS with injury mechanism at the early stage of treatment in the emergency department.


Tae Hoon KIM, Yun Deok JANG (Busan, Republic of Korea), Jun Bo MOON
08:30 - 17:40 #11132 - Factors that influence length of stay and use of resources in the fast-track area of an emergency department.
Factors that influence length of stay and use of resources in the fast-track area of an emergency department.

Emergency Department (ED) overcrowding is a growing universal problem. Among the various interventions that have been tried in EDs around the world to address the problem of overcrowding, the implementation of a “fast track” area and the streaming of patients with limited needs of resources and time to that area, has been proved to be a safe and effective strategy. Such areas have limited staffing and resources and their efficiency depends on the appropriate selection of patients.

In this study, we analysed the data of 3988 consecutive ambulatory patients who were assessed at the Urgent Care Centre (UCC) of the Royal Sussex County Hospital in Brighton UK, during September 2016. UCC plays the role of the fast track area and is staffed by Emergency Department doctors, as well as by General Practitioners (GPs) and Emergency Nurse Practitioners (ENPs). The focus of the analysis was on the length of stay (LOS) and the amount of resources used for this cohort of patients with the aim to identify factors that influence these two parameters.

Of the 3988 patients, 414 (10.38 %) had to be moved to a higher acuity area after initial medical assessment. The median LOS of the patients who were discharged from the UCC was 192.5 min and significantly higher for the group of patients who had to be moved to a higher acuity area (354 min). The data from these two groups of patients were subsequently analysed separately. In the first group (discharged from UCC) 13.3 % had blood tests (other than point of care tests) and 2.82 % had at least one imaging modality (other than plain X-rays) vs 71.98 %  and 13.28 % respectively in the second group.

From the comparison of the results of the two groups, patient related factors that significantly influenced LOS and use of resources were age (higher in the 2nd group) and presenting complaint. Presenting complaints were coded according to Manchester triage. The most frequent presenting complaints in the two groups were “limb injuries” (25.93%) for the group that was discharged from UCC and “unwell adult” (23.91%) for the group that had to be moved to a higher acuity area. The LOS and the use of resources did not seem to be significantly influenced by the seniority of the assessing doctor. Patients assessed by GPs and ENPs had significantly lower LOS compared to Emergency Department doctors, but the spectrum of presenting complaints seen by GPs and ENPs was less broad.

The identification of such factors can contribute to the more appropriate selection of patients suitable for assessment in a fast track area.  Additionally, it can assist in the planning for appropriate staffing and resources in order to provide a more efficient service. 


Nikolas SBYRAKIS (Heraklion, Greece), Christopher TUCKER, Charles PALMER, Martin DUFF
08:30 - 17:40 #11614 - False Claims: A Case Report of a Questionable Head Injury.
False Claims: A Case Report of a Questionable Head Injury.

Fabricated injury is a major problem for forensic experts. Such injuries are also termed as feigned/fictitious/ simulated injuries involving pretense of the patient to present with an injury. We present an interesting case of such a simulated injury in which the patient presented an old surgical craniotomy flap as an entirely new injury. The case was referred to our Institute from a peripheral hospital where the medico-legal report described two incised wounds on the scalp; the primary radiological investigations were reported hemorrhagic contusion and fracture skull. A second examination including a new CT-scan was ordered by the courts at our center. The presence of a healed curvilinear surgical scar and craniotomy flap with burr holes in both the CT-scans were conclusive in detecting feigned injuries by the patient. This case adds to the existing knowledge of fabricated injuries where the patient presented an old surgical scar and craniotomy as an entirely new injury


Luv SHARMA (Rohtak, India)
08:30 - 17:40 #11049 - Family Medicine as gate keepers to the secondary health care system. The United Arab Emirates experience and challenges.
Family Medicine as gate keepers to the secondary health care system. The United Arab Emirates experience and challenges.

In a Western health care system, especially in the United Kingdom, access to the secondary care health system is strictly regulated whereby all patients bar the emergency medicine gain access to secondary services via initial consults and management the primary care health care facility. This holds true for most of Europe and Northern America and aims to reduce the unnecessary economic and logistical burden for the health care system. 

This however is not the case in the UAE whereby all patients could in principle access secondary health care services without going through a family physician thereby increasing the burden on such services.

We will discuss the changing scenario in the UAE with more emphasis being put but by the state heath regulators in improving and providing a high level of services via the primary health care providers will also discuss the impact the impact this will have on the secondary health care providers and in general aim to stream line health care in the Emirates of Abu Dhabi .


Rahat GHAZANFAR (Abu Dhabi, United Arab Emirates)
08:30 - 17:40 #11361 - Fascia Iliaca block to reduce hip dislocation.
Fascia Iliaca block to reduce hip dislocation.

INTRODUCTION

A 15 yrs old boy fell from horse, sustained right hip injury and deformity.

On examination patient right hip was shortened, adducted and internally rotated, with pain score of 10/10. However, neurovascular examination was normal. No other injuries noted.

Isolated dislocation of the right femur was determined clinically, with X-ray’s and by Ultrasound as well.

                                                          

 

TREATMENT

  After discussion with parents and patient, It was decided to give Ultrasound guided Fascia Iliaca block instead of sedation, for pain relief as well as for reduction. After full informed consent and strict aseptic technique, on cardiac monitor, Ultrasound guided injection using 0.5% 2ml/kg bupivacaine was given. No complication noted after FICB. Shortly after the FICB patient pain score reduced .15 minutes after FICB, right hip successfully reduced in first attempt using ALLIS method1, with no complication noted during or after reduction. After procedure patient was hospitalised under orthopaedics for observation and further follow up.

DICUSSION

Posterior hip dislocations are more common 80-90 % as compared to anterior i,e   10-15 %.

Hip dislocations should be reduced within 6 hours.   Because of severe pain and limb position, it is difficult and painful procedure to reduce hip, hence sedation with analgesia is a famous for reducing hip dislocations.

 Ultrasound guided FICB or femoral nerve block can be alternative for managing pain and to reduce hip dislocations, hence reducing ED stay time and complications associated with sedation, especially where sedation carries risk for patient. Same technique could be used in patients for pain, reduction of hip prosthesis dislocations2. Furthermore, these blocks provide prolonged pain relief up to 4-6 hours3, avoiding need for extra pain management after sedation.

 

 

 


Kiren GOVENDER, Muhammad Zeeshan AZHAR (Barrow in Furness, United Kingdom)
08:30 - 17:40 #11735 - Fatigue and Hyperthermia After Physical Exertion.
Fatigue and Hyperthermia After Physical Exertion.

INTRODUCTION :

Excessive or intense exercise beyond the extent of personal or physical limits may induce various types of musculoskeletal damage, including exercise-induced rhabdomyolysis (exRML), a pathophysiological condition of skeletal muscle cell damage. Previous studies have reported that possible causes of exRML were associated with excessive eccentric contractions in high temperature, abnormal electrolytes balance, and nutritional deficiencies possible genetic defects.  In many cases, the presentation of early, uncomplicated rhabdomyolysis is subtle, but serious complications arise if severe exertional rhabdomyolysis is undiagnosed or untreated .

CASE PRESENTATION :

A 29-year-old male applied to the emergency centre with weakness, muscle pain, nausea, that started after a severe exercise high temperature.The patient’s medical history excluded other possible causes of rhabdomyolysis such as trauma, infection, alcohol intake, drugs or cigarette use . His physical examination find a fever at 39°C . Laboratory values revealed the following: serum urea 7 mmol/l, creatine 120 µmol/l, lactate dehydrogenase (LDH) 1927 IU/L (120–230), creatine phosphokinase (CPK) 3903 IU/L (25–190), aspartate aminotransferase (AST) 834 IU/L (10–40) and alanine aminotransferase (ALT) 376 IU/L (10–40).All other tests, which included troponin, coagulation parameters, arterial blood gas were normal. Chest X-ray and electrocardiography were normal.

Considering the patient’s history, clinical findings and laboratory abnormalities, acute rhabdomyolysis due to severe exercice and hyperthermia were diagnosed. The patient was hospitalised and treated symptomatically in the following days. The treatment resulted in the complete resolution of symptoms and signs. Abnormal blood values gradually decreased to normal levels and the patient was successfully discharged.

CONCLUSION :

The emergency doctor has to recognise the symptoms of rhabdomyolysis early and sought diagnosis and treatment. The most important complication is acute renal failure, which occurs in 5–7% of cases. Athletes, coaches, training and medical professional, as well as general population  should be provided with information necessary to identify various conditions that may lead to exRML as well as how to prevent it.

 


Yousra GUETARI (Tunis, Tunisia), Rim HAMMAMI, Mounir HAGUI, Houda NASRI, Mehdi BEN LASSOUED, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #10868 - Feasibility of a prehospital acute dyspnoea score – a pilot study.
Feasibility of a prehospital acute dyspnoea score – a pilot study.

Title

Feasibility of a prehospital acute dyspnoea score – a pilot study.

Authors

Tim Alex Lindskou, registrered nurse, master of science, PhD fellow 1; Erika Frischknecht Christensen, MD, clinical professor, consultant1 2; Allan Winther Kjær Sørensen, Ambulance Professional Leader Thy-Mors3

1) Center for Prehospital and Emergency Research, Department of Clinical Medicine, Aalborg University, Denmark
2) Emergency Clinic, Department of Anaesthesiology and Intensive Care, Aalborg University Hospital, Denmark
3) Falck Denmark A/S, Thisted, Denmark

Aim

Dyspnoea is frequent symptom among patients in ambulances after calling the emergency number, and mortality is high (1). However, knowledge regarding patient experience is sparse. As a first step in assessing subjective intensity of acute dyspnoea, we performed a pilot study in a prehospital setting.

Methods

A one-month pilot study in the Thy-Mors region of the North Denmark region. Emergency ambulance patients with difficulties breathing were asked to use a verbal rating scale to assess their dyspnoea at; 1) first arrival at patient, 2) approximately halfway to hospital, and 3) arrival at hospital.

Results

We included twenty-one patients, 76% were able to use the scale. Five were unable: two due to severe difficulties breathing i.e. an urgent acute situation, one due to difficulties understanding the scale, and two with no reason noted.
Arrival at patient scores (median 8, confidence interval 6-8) were significantly higher than halfway scores (5, 3-6, P<0.001) and arrival at hospital scores (4, 3-5, P<0.001). The scores covered a wide range of the scale at each measurement, with values ranging from; 1) 4-10, 2) 0-8, and 3) 0-8.

Conclusion

The pilot study showed that 76% were able to use the scale. Scores were distributed on a wide range of the scale at all three measurements, and a significant decrease in scores were registered over time. These results indicate that the use of a verbal rating scale is feasible for assessing subjective intensity of acute dyspnoea in the prehospital setting.


Tim LINDSKOU (Aalborg, Denmark), Allan SØRENSEN, Erika CHRISTENSEN
08:30 - 17:40 #11452 - Feber and hepatic nodules. Is this a lymphomatous recurrence?
Feber and hepatic nodules. Is this a lymphomatous recurrence?

CASE REPORT: A 42 year-old woman, Peruvian native, with a history of diffuse large B-cell lymphoma in cavum, diagnosed in 2010 and treated with chemotherapy (ChT) achieving complete remission in 2011. She is attended in the Emergency Department because of epigastric and right upper quadrant pain with fever and physical discomfort during the previus week. On physical examination, hepatosplenomegaly is disclosed but no other relevant information is found. Abdominal ultrasound reports the existence of focal abnormalities in liver echostructure. Complete blood analysis is requested showing cholestasis, hepatic cytolysis and pancytopenia.

DIFFERENTIAL DIAGNOSIS: Recurrence of lymphoma, metastasic disease with unknown origin.

EVOLUTION: With suspect of lymphomatous recurrence, she is admitted to the hospital. The thoracic-abdominal-pelvic Computed Tomography (CT) scan demonstrates the presence of multiple lesions in liver and spleen consistent with metastatic disease (Figure 1) and suggestive of lymphomatous recurrence. With this suspicion, ChT cycle with cyclophosphamide, doxorubicin, vincristine and prednisone (CHOP) is administrated and at the same time a bone marrow aspirate is performed obtaining important tissue necrosis, plasmacytosis and megakaryocytic hyperplasia compatible with malignant histiocytosis without recurrence of lymphoma (Figure 2).

FINAL DIAGNOSIS: Malignant histiocytosis

DISCUSSION: Malignant histiocytosis is a rare entity in which histiocytes have sharp features of atypia and few hemophagocytosis. It can develop at any age, without gender difference and presents with hepatosplenomegaly, lymphadenopathy, skin and bone lesions, pulmonary infiltrates and central nervous system affectation. In peripheral blood it is usually observed pancytopenia by histiocytic infiltration of the bone marrow observing sometimes circulating atypical cells. Given the rarity of this disease, there are no large prospective trials. There is no standardized therapy for histiocytic sarcoma, and one of the most common is ChT using similar standards to high malignancy lymphomas based on CHOP therapy. Although the ChT administered might have been effective, the evolution of the patient was fulminant due to the massive infiltration and consequent progressive multiorgan dysfunction.


Marta JORDÁN DOMINGO, Daniel SÁENZ ABAD (ZARAGOZA, Spain), Cristina BAQUER SAHÚN, Carmen LAHOZA PÉREZ, Mercedes JIMÉNEZ CASADO, Jordi PONS DOLSET
08:30 - 17:40 #11082 - FEBRILE AGRANULOCYTOSIS IN THE EMERGENCY DEPARTMENT.
FEBRILE AGRANULOCYTOSIS IN THE EMERGENCY DEPARTMENT.

Female patient, 58 years old, no known allergies to medication. Crohn’s disease, on treatment with mesalazine 2 g/24 hours.

She went to emergency department because she had fever of 38º Celsius, without no other symtomps. Clinical examination was normal, save fever. Blood test showed 2.800 leukocytes, 390 neutrophils, 11 Hb, and 208.000 patelets. Coagulation and biochemistry test were normal.

Since, febrile agranulocytosis of the patient a possible drug effect was suspected. Mesalazine was suspended, and began broad spectrum of antibiotherapy.

Aetiology of agranylocytosis, can be in terms of bone marrow supression (failure of cells production) (this involves drugs’ agranulocytosis, nutritional deficiency or infiltration by tumor cells); or by peripheral destruction (hypersplenism, autoimmune disorders).

The pharmacological compounds to produce agranulocytosis are: analgesics and NSAID (mesalazine, ibuprofen…); diuretics (thiazides); antihistamines; antiepileptic drugs; antidepressants; antibiotics (cephalosporins, ciprofloxacin, metronidazole…); drugs for cardiovascular diseases (propranolol, captropril); psychotropic drugs (risperidone, diazepam); and other drugs as antivirals drugs or allopurinol.

In this case, and after checking patient’s treatment, mesalazine was suspended. After that has been shown to increase neutrophil number.

Medication is the most frequent cause of agranulocytosis. In emergency department is possibble checking drugs’ list causers of agranulocytosis and suspended it. Recovery of neutrophils’ number is along 2-3 days, and it’s complete at 10 days.

In case of moderate or serious agranulocytosis (less than 1000/mm3), there is high risk of infection, and it will be necessary to provide prophylactic antibiotic coverage.

 

CONCLUSIONS

In case of febrile agranulocytosis, there is reasonable cause to suspect pharmacological aetiology. Emergency measure is retire drug guilty and begin broad spectrum of antibiotherapy, in case of moderate-serious agranulocytosis. 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #10987 - Fever and headache... when the cause is... a mosquito!
Fever and headache... when the cause is... a mosquito!

R.G. a 83 years old man with a History of BPCO, neck arthrosis, ischemic cardiac disease, hypertension, prostatectomy and appendicectomy presented to the hospital complaining of a 10-day history evening fever, headache and neck pain. He had assumed ciprofloxacin from 3 days without benefits. He denied travels abroad. The physicaland neurological examination was otherwise unremarkable except for submental lynfoadenopaty. Laboratory values showed only elevated CRP. Also serology for Shypillis, EBV, hepatities, Cryptococcus, screening for cancer, ANA-reflex and C3-C4 were negative. Chest XR and abdomen-US were normal. Neck-US shows chronic sialadenitis, in follow up. He had spent two weeks near Ferrara seaside, so, according to the epidemiology, we decided to study sierology for West-Nile Virus (WNV) and Chikungunya, detecting positive IgM and IgG  for WNV. Head-CT, EEG and FOO were negative. In the meantime His neurological status deteriorated with new cerebellar syndrome symptoms. Cerebrospinal fluid (CSF) analysis confirmed WNV infection. Supportive care was continued, with progressively improving until dischargement. During follow-up the patient referred headache, consistent with his desease. The WNV is a flavivirus, transmitted from Culex mosquitos. He reproduces itself inside birds, men and other vertebrates are incidental hosts. The clinical presentation is usually aspecific. More than 80% of the patients don’t manifest any symptoms, while in few cases the infection is characterized by the west-Nile fever: an abrupt onset of fever, headache, malaise, back pain, myalgia, anorexia, dyspepsia and a maculopapular rush (not always present). Another possible clinical manifestation is the neuroinvasive desease that occurs when the virus penetrates the blood-brain barrier and invades certain groups of neurons, in particular the brainstem, deep nuclei, and anterior horn of the spinal cord. This form of the desease is characterized by fever in conjunction with meningitis, encephalitis, flaccid paralysis, or a mixed pattern of diseases. The diagnosis is helped maintaining high suspicion when clinic and history of exposure to the vector in endemic areas is present, leading to check WNV IgM antibody on serum. Moreover if neurological symptoms are present, lumbar puncture and CSF for IgM antibody testing is indicated. Usually labs and imaging are aspecific. An accurate history about living places or travel habits is fondamental. It is useful to also remeber that altough it is considered a tropical desease, the infection is present in the Old World, throughout Africa, the Middle East, parts of Europe and the former Soviet Union, South Asia, and Australia. In Europe it is present in Italy, Romania, Austria, Hungary, Cyprus, Croatia, Bulgaria. The treatment is based on supportive care. West Nile Virus (WNV) could be characterized by significant morbidity and mortality; high clinical suspicion should be present to diagnose this disease.


Chiara PIGNATTI, Elena CARELLA, Marina BUDA, Sabrina LUPACCIOLU, Francesca MORI (MODENA, Italy), Brugioni LUCIO, Sara CIAFFI
08:30 - 17:40 #11348 - Fever and polyarthralgias as a means of diagnosis.
Fever and polyarthralgias as a means of diagnosis.

Lyme disease is an emerging infection caused by the spirochete Borrelia burgdorferi. It is considered the new "great imitator", being its diagnosis a challenge. It is divided into four stages, early localized disease, early dissemination, late disease, and post-Lyme syndrome. Clinical manifestations can be cutaneous and systemic, and may have cardiovascular, neurological and musculoskeletal involvement. The diagnosis is based on clinical findings and can be confirmed by serological studies. The goal of antibiotic treatment is to relieve symptoms and prevent sequelae. A minimum percentage of patients with fatigue, musculoskeletal pain and other symptoms lasting more than 6 months are called post-Lyme syndrome and after adequate treatment the disease resolves.

We present the case of a 42-year-old woman attending the emergency room because of polyarthralgia of a month of evolution

On her medical record there's an anxiety-depression syndrome.

She arrives in the emergency room with intense pain in the inner part of the right leg of the thigh, right knee and ipsilateral hip, as well as loss of strength in the lower right extremity and diffuse arthralgias.

On the patient interview she stated that she had suffered from several insect bites over the last months. Though there was no history of skin lesions she began with numbness and weakness in the lower right limb for the last two weeks. For the last two days the pain intensified over the shoulders, elbows, wrists and hips. She denied fever.

On the physical exploration we found temperature of 38,5ºC. The rest of the vital signs were normal. The patient refers pain when we touch both her lower limbs, the pain is more pronounced in the inner side of the right thigh. Also we found loss of strength with hypoesthesia through the lower right limb.

Blood tests were performed and the results were within normal ranges. EKG was normal. A CT scan was performed and it was normal.

Under the suspected diagnosis of lyme disease, we request serological tests for Burgdoferi which came back with the IgM positive.

The patient was hospitalized and treatment with doxycycline and nonsteroidal anti-inflammatory drugs was started, over the first week there was no clinical improvement so we added ceftriaxone and after one month of hospitalization the patient was discharged because she showed signs of clinical improvement. The selorogical tests were repeated and they came back negative. The follow-up has been given to her primary care physician.

Bibliography

1. Stanek G, Wormser GP, Gray J, Strle F. Lyme borreliosis. Lancet 2012; 379:461.


Noelia SANTOS (Mortera, Spain), Valentina ACOSTA RAMON, Maria Del Pilar CARLOS GONZALEZ, Marta BÁSCONES GARCÍA, Marta PASTRANA FRANCO
08:30 - 17:40 #11432 - Fibrinolysis in the first hours with relative contraindications.
Fibrinolysis in the first hours with relative contraindications.

We present a case of a 52-year-old woman with no allergies, high blood pressure, paroxysmal atrial fibrilation with normal echocardiogram, dyslipidemia without treatment , anemia due to metrorrhagia and recent conization by in situ carcinoma of the cervix. She moved to emergency room for assessment by ictal episode of difficulty for oral expression, right hemicampimetric vision loss, with sequential recovery in one hour. Physical examination: rythmic tones without murmurs. No neurological focal signs. In complementary tests hemoglobin of  10.1 g/dl , EKG: sinus rythm without alterations in repolarization.  CT scan: Hypodense lesions in anterior arm internal capsule and subcortical  white matter right and temporoparietal left of possible ischemicdegenerative origin. Heparin anticoagulation was initiated at therapeutic doses and subsequently  new oral anticoagulants . During her stay in ER she started  again with left hemiparesis, left facial paresis and deviation of the gaze conjugated to the left; The  ¨Stroke code ¨ was activated, she showed NIHSS 17,  a second CT  scan was performed with no new lesions and remaining with the symptomatology for more than 45 minutes. It was decided to propose intravenous fibrinolytic treatment to the relatives, preceded by a risk / benefit explanation, due to the beginning of the anticoagulant treatment and metrorrhagia by recent conization; Treatment was accepted and fibrinolysis began, with a good response, NIHSS 1-2 posterior. At discharge, the patient was asymptomatic.

Conclusions

Intravenous fibrinolysis is an indication for the established stroke in the first 4 and a half hours and should therefore be evaluated with the existence of relative contraindications such as the initiation of anticoagulation and minor hemorrhages.


María Palma BENÍTEZ MORENO, Marta JIMÉNEZ PARRAS (SPAIN, Spain), María Lucía MORALES CEVIDANES, Carlos DE LA CRUZ, María Paz ORTIGOSA ARRABAL
08:30 - 17:40 #11878 - First aid a century ago in Romania. Still actual?
First aid a century ago in Romania. Still actual?

BACKGROUND

Everybody knows that First aid is the provision of initial care for an injury usually performed by non-experts, but people that prepared themselves to be able to help a sick or injured person until definitive medical treatment can be accessed. Still, millions of people are hurt or killed from injuries every year because adequate and timely assistance is not provided. Romania has only a century of modern medicine and before XIX century first aid was even more exceptional. Under the name of "Popular Medicine" basic instructions were provided to communities in Romania  to substitute the lack of doctors.

Our study based on literature and guides older than 100 years highlights the good advises and the unfortunate ones related to first resuscitation, burns and trauma. 

METHODS

I have used a set of very rare and old books to highlight the older popular protocols and they are compared with the current ones.

RESULT

Surprisingly the old popular advises offer a lot of interesting surprises as some advises are more actual than ever comparing to others that are naive and childish.

CONCLUSIONS

People wisdom and experience are sometimes imperfect but there are still things to learn from. There is always worth to go back to old ways and analyze some advises through the eyes of the modern world.


Marius SMARANDOIU (Sibiu, Romania), Alin CANCIU, Dania LUNCA
08:30 - 17:40 #11974 - First responders as an important factor survive in ambulance.
First responders as an important factor survive in ambulance.

Theoretical background:

Every day there are 5 or 6 people who die due to the consequences of sudden cardiac death in Slovenia. Not giving first aid and waiting for the rescue team result in the fact that the patient has less chances of survival with every passing minute. We assume that the rescue teams outside city centres have longer reaction times, however, we could solve this problem with First Responders. In the areas out of the city centres the chances of survival would raise significantly.

Methods:

To collect data we used the information health system PROMEDICA, used by Emergency Medical Service of the Health Center Maribor. The patients who were treated in the Emergency Medical Service of the Health Center Maribor in the term from 1st January, 2014 to 31st December, 2014 were included in the reaserch. Out of these we chose the ones who were treated by the Emergency Medical Service in the areas near Maribor, who are from the University Medical Centre Maribor is more than 15 kilometers.

Results:

In the given term there were 1331 cases of rescue intervention in this area. The prehospital emergency team had on average 111 cases of intervention per month. Mostly, there were internist cases, namely 931. On the bases of given reaction times we found that prehospital emergency units need on average 15.21 minutes to arrive to this area, which is more than the Slovenian average and more than 10 minutes, the time in which the patient has some chances of survival.

Discussion:

By launching First Responders in the area discussed, the reaction times of prehospital emergency units would be distinctively shorter. We would raise the quality of medical care and consequently the chances of survival. 


Aleksander JUS (MARIBOR, Slovenia)
08:30 - 17:40 #11302 - First Year of Emergency Medicine in Finland: Qualifacations of the Senior Consultants.
First Year of Emergency Medicine in Finland: Qualifacations of the Senior Consultants.

Objective

Emergency Medicine (EM) became the 50th full length specialty in Finland at the beginning of 2013. The Finnish health care system is based on the five University Hospital districts. In each one there is a University Hospital and two to four Central Hospitals with 24/7 fully operating Emergency Departments (EDs) acting also teaching hospitals for Emergency Medicine Residents.  The six-year curriculum of EM specialist training was built according to international guidelines1,2. Our aim was to study clinical and scientific background of the consultants acting as head physicians of the EDs.

Methods

We carried out a national survey to analyze qualifications of the senior consultants of the EDs. The survey was carried out soon after the onset of the specialty reform. All national EDs initiating the specialist training were included.

Results

The response rate was 100%. There were altogether 28 EDs in Finland commencing a Resident Training Program. In these clinics there were 67 posts of head physician or senior consultant, the mean (+SD) number was 2.39 + 1.50 per clinic. Depending on the size of the hospital there were one to six physicians working on head or senior consultant status in the EDs; however more than half of the clinics had only one or two senior physicians.  Altogether 62 senior posts were occupied. Their specialty background was Internist in 34%, Anesthesiologist in 21%, GP in 21% and Surgeon or Orthopedist in 13%. There were also two physicians with international EP degree and one Neurologist.  While starting the program thirty of the senior doctors had Specific Competence in EM or EMS, six heads were Adjunct Professors and 16 were MD PhD. During the transition period in 2013 seventy one physicians did the Finnish EM examination. Almost all physicians participating in our survey were among them.

Conclusion

The educational background of the head and senior consultants of EDs was fairly versatile and it should be considered as a resource in Resident education. The prerequisite for the senior physicians to pass the EM examination during the one-year transit period strengthened our Resident Training Program.

During the first year of EM in our country, we have adopted international ideas in order to rapidly develop a valid practical training program.  Our study indicates that we have a capable senior staff for the resident education. Our continuing challenge is to find the right balance between routine work, theoretical and practical training. The success of this is based on co-operation of various specialties and also with countries with established EM training programs.

 

References

  1. The EuSem task force on curriculum. European Curriculum for emergency medicine. http://www.eusem.org/cms/assets/1/pdf/european_curriculum_for_em-aug09-djw.pdf
  2. Naskali J, Palomäki A, Harjola V-P, Hällberg V, Rautava V-P, Innamaa T. Emergency Medicine in Finland: First Year Experiences of Specialist Training. J Acad Emerg Med. 2014;13:26-29.

Ville HÄLLBERG (Hämeenlinna, Finland), Jarno NASKALI, Teemu KOIVISTOINEN, Tapio INNAMAA, Palomäki ARI
08:30 - 17:40 #11723 - Five-minute door-to-needle time in acute ischemic stroke.
Five-minute door-to-needle time in acute ischemic stroke.

Background

Intravenous thrombolytic therapy by tissue plasminogen activator (tPA) should be started in case of acute ischemic stroke (AIS) within 60 minutes after patient’s arrival to hospital. However, much shorter time interval is justifiable, because each minute saved from the delay of the treatment may improve significantly patient’s post-stroke lifetime. We have organised an Emergency Physician (EP) based treatment protocol to achieve door-to-needle time (DNT) of 20 minutes or less. We present here a patient with AIS with a very short DNT treated in our ED.

Patient Case

Our AIS patient was a 57-year old Caucasian man, who had hypercholesterolemia, sleep apnoea and bronchial asthma. Exactly 180 minutes before the arrival to the ED, he had revealed that his left lower limb abruptly became feeble. He had also felt slight numbness of the left arm. In the ED, the specialist EP got a pre-notification from the Emergency Medical Service 17 minutes before patient’s arrival. He had enough time to study patient record beforehand. In clinical examination, the patient was in a good general condition. He could not raise his left lower limb but could move his toes. His GCS score was 15 and NIHSS 4 (three points from the strength and one from numbness of left lower limb). Neurologic examination did not reveal any other abnormal findings.

Patient’s clinical examination and transfer to computed tomography (CT) located in the ED were carried out according to our established AIS protocol and without extra delays. Cranial CT was studied within three minutes after patient’s arrival to the ED, and it did not reveal any contraindications for thrombolytic therapy. After oral informed consent of the patient, intravenous recombinant tPA therapy was commenced.

One hour after the start of thrombolytic therapy the patient felt full recovery of his left lower limb. Sixteen hours later, his NIHSS was only one (slight numbness in the left leg). In the neurologic ward, he had some fluctuations of his symptoms, but finally he recovered well.

Discussion

Our case is an example of good results achieved in AIS, when an EP based treatment protocol is functioning well in every sense. At present, the median DNT in our ED is around 18 minutes. In this case we were possible to achieve very short DNT of five minutes with a favourable outcome of the patient. We encourage colleagues working in EDs to organise a scrutinized and fluent treatment protocol of AIS in cooperation of different specialties to achieve short DNTs.


Ari PALOMÄKI, Markku GRÖNROOS, Jarno NASKALI (Seinäjoki, Finland)
08:30 - 17:40 #11959 - Flecainide acetate intoxication: a cas report.
Flecainide acetate intoxication: a cas report.

Flecainide acetate is a class Ic antiarrhythmic prescribed primarily for the treatment of ventricular dysrhythmias. It also has local anesthetic properties that depress myocardial contractility. Flecainide is usually available in 100 mg tablets. Intoxications with this drug are seldom. Flecainide-induced tachycardia is a life-threatening condition, which has rarely been observed. We described a case occurring in a young patient.

A 16-year-old girl was admitted to the emergency department (ED) for altered mental status and fatigue, after an attempted suicide with a flecainide overdose of 1.2 g (about 12 pills of flecainide 100 mg). Her previous medical history revealed a Wolf Parkinson White syndrome, treated by 3 failed attempts of radiofrequency ablation. Her usual medication included flecainide. On admission, her vital signs were as follows: blood pressure 70/50 mm Hg, heart rate 30 beats/min, and a temperature of 37.3°C. The physical examination revealed a drowsy patient without any clinical signs of heart failure and no history of syncope. Family history for sudden death was negative. Her metabolic panel was normal: sodium 123 mmol/L, potassium 3.8 mmol/L, creatinine 60 μmol/L. Her ECG revealed a membrane stabilizing activity.

The patient was admitted to our cardiology unit for continuous rhythm monitoring and received hypertonic sodium bicarbonate. She was transferred to a general ICU and had an endotracheal intubation.

 

Whereas drug overdose in general has an overall mortality of less than 1%, intoxication with antiarrhythmic drugs of class IC was associated with a mean mortality of 22.5%. In one large series, Nausea, which occurred within the first 30 minutes after ingestion, was the earliest symptom. Spontaneous vomiting probably led to self-detoxication in about half the patients. Cardiac symptoms including bradycardia and, less frequently, tachyarrhythmia occurred after about 30 minutes to 2 hours. Fatal outcome was mainly due to cardiac conduction disturbances progressing to electromechanical dissociation or asystolia. Since a specific treatment is not available and resuscitive procedures including sodium bicarbonate and insertion of a pacemaker are of limited therapeutic value, early diagnosis and primary detoxification are most important for prevention of fatal outcome.

 

 

Therapeutic measures included administration of activated charcoal, gastric lavage and a saline laxative, catecholamines, and in some patients, hypertonic sodium bicarbonate, insertion of a transvenous pacemaker and hemoperfusion


Zied GUERMAZI (Trévenans), Sami KASBEOUI, Afef BEN HALIMA, Zied IBN EL HADJ, Marouene BOUKHRIS, Lobna LAAROUSSI, Ikram KAMMOUN, Selem KACHBOURA
08:30 - 17:40 #10946 - FLECAINIDE TREATMENT IN PATIENTS WITH ATRIAL FIBRILLATION. EFFECTIVENESS AND SECURITY IN EMERGENCY DEPARTMENT.
FLECAINIDE TREATMENT IN PATIENTS WITH ATRIAL FIBRILLATION. EFFECTIVENESS AND SECURITY IN EMERGENCY DEPARTMENT.

1) Introduction and Objectives:

To describe the management of patients with recent – onset (

 

2) Material and Methods:

A prospective, observational study consecutively enrolled patients over 14 years old who were attended at an Emergency Department presenting atrial fibrillation from January 1, 2011 to December 31, 2016. Data were collected in FileMaker Pro 12 database from the patient's computerized medical history (PCH).

 

3) Results:

A total of 2935 patients with AF were included. Flecainide was used for pharmacological cardioversion in 256 patients (8.72%). The average age was 56 years; one hundred and eighty – one patients were males (70.7%) and the average CHA2Ds2 score was 0.7.  Successful cardioversion was achieved, recovering stable sinus rhythm in 221 cases (86.5%). Four adverse effects (1.56%) were reported. The average stay was 6.9 hours concluding with a 99.5% hospital discharge.

 

4) Conclusions:

1) Antiarrhythmic drugs are essential in the practical strategy of the pharmacological approach of patients with AF. The class IC antiarrhythmic agents’ safety and effectiveness have been proved in patients without underlying heart conditions.

 

2) Flecainide is an effective alternative when used for rhythm control strategy in AF. Its use indications for pharmacological cardioversion at the ED are patients presenting specific profile: 56-year-old men without cardiovascular risk factors (CHA2DS2 score of 0.7 on average).


Marta DEL PUEYO PARRA, Victoria ORTIZ BESCÓS (Zaragoza, Spain), Román ROYO HERNÁNDEZ, Isabel PÉREZ PAÑART, Patricia ALBA ESTEBAN, Joaquín GÓMEZ BITRIÁN
08:30 - 17:40 #11148 - Food anaphylaxis in an emergency department: epidemiology, clinical features and management.
Food anaphylaxis in an emergency department: epidemiology, clinical features and management.

Background:

Anaphylaxis is defined as a serious allergic reaction that is rapid in onset and may cause death in otherwise healthy individuals. Food-induced anaphylaxis is considered to be one of the leading causes of anaphylaxis treated in emergency departments (ED) and its prevalence is increasing.

Objective: Describe the epidemiology, clinical features, management and outcome of patients with food anaphylaxis.

Methods: Prospective, monocentric study over five years. Inclusion criteria: patients aged over 14 years presenting consecutively to ED with the diagnosis of anaphylaxis. Collection of epidemiological, clinical and therapeutic parameters.

Results: Inclusion of 643 patients presented in the ED with the diagnostic of anaphylaxis. Food anaphylaxis was found in 161 (25%) patients. Mean age = 36±14 years. Sex-ratio=0.78. A history of anaphylaxis was reported in 35 % of cases. The most incriminated foods were:  sea-food (43%), fishes (20 %), tuna (15%) and fruits (6%). The median time to consult the ED was 120 minutes, with extremes ranging from 5 minutes to 33 hours. Cutaneous features were present in 95% of patients. Respiratory, cardiovascular, gastrointestinal and neurologic features were found respectively in 32, 20, 12 and 0.6%.  An anaphylactic shock was recorded in 16 patients (10%). Anaphylaxis was moderate grade in 72 patients (45%). Adrenaline was used in 38%of patients, intravenously in 10%.  Fluid resuscitation was given to a third of the patients. Eighty-five patients (53%) received histamine H1 antagonist, 98% corticosteroids. All of the patients were discharged directly from ED after a mean period of observation as 4 hours. Biphasic reactions were reported in one patient. There was no death cases registered. Patients were all referred to the allergy clinic.

Conclusion:

Identifying the characteristics of food anaphylaxis presentation to ED and its risk factors helps to improve the diagnosis of this medical emergency and suggest the necessity of a standardized guideline for anaphylaxis management in ED.


Hanen GHAZALI (Ben Arous, Tunisia), Siwar JERBI, Rihab DIMASSI, Anware YAHMADI, Mouna GAMMOUDI, Mahbouba CHKIR, Monia NGACH, Sami SOUISSI
08:30 - 17:40 #11262 - Foot drop: an unusual presentation of Acute Spontaneous Spinal Epidural Haematoma (ASSEH).
Foot drop: an unusual presentation of Acute Spontaneous Spinal Epidural Haematoma (ASSEH).

Foot drop is a common presentation in the Emergency Department. It is caused by damage or compression of the common peroneal nerve due to a variety of reasons. Rarely, spinal cord conditions such as Acute Spontaneous Spinal Epidural Haematoma (ASSEH) can present as foot drop.

A 65-year-old lady presented to the Emergency Department with a three day history of weakness and foot drop in the left lower extremity.  She was on a cruise when she developed non-traumatic sudden severe left sided neck and shoulder pain. A diagnosis of frozen shoulder was made by the ship medical team and was commenced on opiates. She then developed left lower leg weakness and foot drop which she thought was due to opiates. The neck pain subsided, however due to ongoing left lower limb weakness and foot drop she presented to the Emergency Department. She was then reviewed by multiple teams and finally an MRI scan demonstrated an epidural haematoma at the level of C4 to T1.  

The patient was referred for urgent surgical decompression of the spinal canal.  She made a steady recovery, and was subsequently discharged home. 

Acute Spontaneous Spinal Epidural Haematoma (ASSEH) is a rare condition with an incidence of 0.1 per 100,000/year. In the presence of a neurological deficit, the treatment for ASSEH is urgent decompression and evacuation of the haematoma. If not promptly diagnosed and treated, ASSEH can rapidly progress to life changing or life threatening neurological deficit. This case report demonstrates the importance of history taking and appropriate examination. One of the differential diagnosis to remember in a patient presenting with sudden severe back or neck pain and neurological deficit is ASSEH. MRI scan remains the gold standard in the diagnosis of ASSEH. In the absence of neurological deficit, this condition could be managed conservatively.

References: Idiopathic Thoracic Spontaneous Spinal Epidural Hematoma. Aycan A, Ozdemir S et al. Case reports in Surgery. Volume 2016 (2016), Article ID 5430708, 4 pages http://dx.doi.org/10.1155/2016/5430708


Nisha MALLYA (Swansea, United Kingdom), Ann PAYNTER, Nicholas DAVIES, Suresh PILLAI
08:30 - 17:40 #11219 - Forearm Abscess Mimicking Septic Arthritis of Wrist: A Case Report.
Forearm Abscess Mimicking Septic Arthritis of Wrist: A Case Report.

CASE PRESENTATION

A normally well, independent 77 year old female presented to Accident and Emergency, feeling generally unwell and complaining of left wrist pain. She had a background of pulmonary fibrosis, pulmonary hypertension and hypothyroidism.
She was septic on arrival and was resuscitated according to the sepsis protocol. Initially identified as a possible community acquired pneumonia. This was not, however, convincing on auscultation and her chest x-ray showed no consolidation. No other source of sepsis (urine, abdominal, skin) was identified. Her wrist was unremarkable on clinical examination, but isolated extreme pain in the Left wrist was noticed, not controlled by morphine. There was no history of trauma or skin breaks to the affected wrist or forearm.

INVESTIGATIONS

  • Biochemistry on admission: White cell count 21 x 109 g/L, CRP 372 mg/L
  • Chest X-ray in A&E: no evidence of focal consolidation.
  • Ultrasound scan of left wrist with attempted aspiration 12/02/16: No significant effusion or synovitis within the wrist joint. A small lesion within the anterior compartment of the distal forearm noted but no inflammatory change to account for the severity of symptoms.
  • US Doppler upper limb veins 13/02/16: Patent subclavian and axillary veins.
  • MRI Left Forearm 13/02/16: Effusion in the distal radio-ulnar joint and within the intercarpal joints. Fluid seen tracking along the soft tissues within the long arm flexor tendon compartment of FDS and FDP. No convincing evidence of septic arthritis.
  • Venous stab blood cultures: β-haemolytic group A streptococcus (Penicillin and Clindamycin sensitive)

 

TREATMENT

The patient was immediately commenced on intra-venous antibiotics. She did not however show much improvement and underwent a surgical exploration 3 days into admission. Intra-operatively her symptoms were diagnosed as an abscess in the forearm with appearances suggestive of necrotising fasciitis. She had extensive debridement of the soft tissues and had thorough washout of the wound.

OUTCOME AND FOLLOW UP

Following surgical debridement, the patient was transferred to Intensive Care. She had a prolonged recovery with subsequent development of pulmonary emboli, however made stable progress and was discharged to a rehabilitation hospital 1 month after initial presentation.

LEARNING POINTS

Even in the absence of classical clinical signs (such as erythema, swelling and skin necrosis), in patient with risk factors (such as diabetes or immunosuppression), a septic picture combined with isolated atraumatic limb pain should be considered sinister as a deep abscess or even necrotising fasciitis in extreme cases. Urgent surgical exploration is mandated with involvement of orthopaedic or surgical team as appropriate. Ths case was a very rare presentation of a deep tissue abscess mimicking septic arthritis and needed close collaboration of ED, Medical and Orthopedic teams.


Awais CHEEMA, Thillainayagam SRIRAM (London, United Kingdom), Maddy GIMZEWSKA
08:30 - 17:40 #11076 - Foreign bodies.
Foreign bodies.

CASE REPORT: A 36 year old woman with a history of borderline personality disorder. appears on 6 occasions by repeated ingestion of different objects (knives, teaspoons, toothbrushes, dominoes, plastic plugs, eyeglass temples or a crucifix) (Figure 1). In all cases, the patient maintains good general condition, does not present analytical alterations and the objects can be seen in the radiological studies, needing endoscopic removal of the different objects. Despite the repeated recommendations to avoid this type of behavior the patient consults in a seventh time presenting on this occasion intense abdominal pain after the ingestion of a dessert knife. In the exploration, the patient is diaphoretic, affected by pain, tachypneic (20 breaths per minute), hypotensive (80/45), febrile (39ºC) and clear signs of diffuse peritoneal irritation.

DIFFERENTIAL DIAGNOSIS: peritonitis in the context of foreign body gastric perforation, peritonitis due to foreign body colon perforation, mediastinitis in the context of foreign body esophageal perforation, sepsis of another abdominal origin (appendicitis, cholecystitis ...)

EVOLUTION: with suspicion of severe sepsis in the context of hollow viscera perforation by any of the foreign bodies ingested by the patient, analytical (leukocytosis (16,000), lactate 5.4 mmol/L, pH 7.20, bicarbonate 14 mmol/L) and radiological studies were performed showing images compatible with gastric and domino knife and blind level compatible with crucifix (Figure 2) and pneumoperitoneum (Figure 3). Urgent thoracoabdominopelvic computed tomography (CT) with intravenous contrast was performed showing moderate pneumoperitoneum in relation to the presence of a gastric cavity knife with perforation (Figure 4). In addition it is observed a tab of domino in gastric body and a crucifix in colon without signs of perforation. Faced with these findings, a consultation is requested for surgery that performs urgent laparotomy with extraction of the knife and primary suture of the perforation.

FINAL DIAGNOSIS: gastric perforation by foreign body ingestion (knife)

DISCUSSION: intake of foreign bodies is relatively frequent in Emergency Departments. Most are produced with autolytic purpose although sometimes it is accidental intakes. Despite the frequency with which we face this situation, there are few Emergency Services that have a specific protocol of action and are not always clear indications of urgent endoscopy. Recently, the European Society of Digestive Endoscopy (ESGE) has published guidelines which summarize the management of this type of patients according to the type of object ingested, the place where they are housed and the presence or absence of complications related to the episode (obstruction, perforation ...). We have created algorithm 1 to summarize the ESGE recommendations.

 

 


María Del Carmen LAHOZA PÉREZ (ZARAGOZA, Spain), Daniel SÁENZ ABAD, Marta JORDÁN DOMINGO, Jordi PONS DOLSET, Ana ILUNDAIN GONZÁLEZ, Sofía LUNA GARCÍA
08:30 - 17:40 #11872 - Forms of clinical presentation and evolution in patients with AF in ER Introduction.
Forms of clinical presentation and evolution in patients with AF in ER Introduction.

Introduction

The diagnosis of Atrial Fibrillation requires control of the heart rhythm by an CGS. AF can present as symptomatic or asymptomatic ("silent AF"). AF is frequent and with severe utilization, early CGS is an effective and economical method for its diagnosis. Early detection could condition treatment and improve outcomes.

Goals

To analyze the relationship between the symptomatology of AF presentation and the duration of the symptomatology.

Material and methods

Retrospective observational study in a general hospital with a population of 200,000 and 275 emergencies per day. The patients included was those who were diagnosed with AF treated in our service between October 2012 and December 2013. The symptoms studied were dyspnea, syncope, chest pain, dizziness, thromboembolic alterations, palpitations and a casual finding.

Results

The total number of patients was 764.
Of those who presented dyspnea (31.8%), 41.5% less than 48h, 23.8% more than 48h and 29.2% undetermined.
As for syncope (2.8%), 9% for exposure over 48h, 18% indeterminate and 72% less than 48h.
With regard to thoracic pain (24.8%), 13.2% for presentation of 48h, 12.7% of indeterminate form and 73.5% for less than 48h.
12.3% had dizziness, 27.65% undetermined, 13.8% more than 48 hours and 58.5% less than 48 hours.
Those with thromboembolic alterations, 60% less than 48 hours and 40% undetermined.
48.4% presented palpitations, 15.9% more than 48 hours, 14.3% indeterminate and 68.8% less than 48 hours.
7.48% were diagnosed as having FA at random, 10.52% more than 48 hours, 87.7% were undetermined and 1.75% were less than 48 hours.

conclusion

According to the clinical practice guidelines, the time of evolution determines the part of the management of AF. Asymptomatic AF (diagnosis by chance) or with nonspecific symptoms (dizziness, dyspnea ...) can lead to serious consequences such as stroke or death, mainly due to antiarrhythmic treatment and anticoagulation, these forms of presentation being frequent in our service. It would be recommendable Consider performing the ECG a population at risk (elderly, cardiac ...) to improve this situation.


Blanca DE LA VILLA ZAMORA, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Fernandez-Camacho DANAE, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain)
08:30 - 17:40 #11578 - Full blood count parameters and venous thromboembolism: is there any value for the emergency physician?
Full blood count parameters and venous thromboembolism: is there any value for the emergency physician?

Background: Some studies reported a correlation between some blood count parameters (leukocytes count, neutrophils absolute value, platelets count, red cell distribution (RDW), mean platelet volume (MPV)) and venous thromboembolism (VTE). They compared patients with known thromboembolic disease such as deep venous thrombosis (DVT) as well as pulmonary embolism (PE) to healthy control groups founding that higher RDW and MPV levels may have diagnostic and prognostic features. Many clinical decision rule have been proposed to assess pre-test probability and risk stratification mainly for PE although full blood count parameters are not considered as variables in these scores. However there are few studies performed in the Emergency Department (ED) about this correlation. The aim of our study was to analyse full blood count parameters of patients presented to the ED and investigated for suspected VTE in order to identify clinical probability and prognostic characteristics. Methods: We performed a retrospective observational study based on electronic medical records of patients presented to the ED of the San Martino University Hospital of Genoa, Italy, between January 2014 and December 2015. All patients were investigated for VTE and underwent computed tomography pulmonary angiography and duplex ultrasound. Based on these results, they were divided into four classes: PE, isolated DVT, PE plus DVT and non-DVT non-PE group. We used the revised Geneva score to assess clinical pre-test probability and the sPESI for prognostic assessment. Leukocyte count, neutrophils, platelets, RDW and MPV values were analysed among the four classes and correlated with the clinical decision tool scores. Results: Of 222 identified patients, 101(45%) were male with a mean age of 70±14,4. 143 had VTE (n=75 with PE, n=40 with DVT, n=28 with both PE and DVT) and 70 were negative for PE and DVT investigations. No significant differences were found among these classes in terms of age, gender, and risk factors. In the VTE group, leukocytes and neutrophils levels were higher (p<0,05) whilst MPV values were reduced (p<0,05). About the relationship to pre-tests clinical probability, we found no significant correlation between the revised Geneva score results and any of the full blood count parameters. Moreover, concerning the correlation with a prognostic test, only RDW was found significantly higher (p<0,05) in patients with sPESI³1. Discussion: The relationship between full blood count parameters and VTE may be intriguing. However our study, based on a population from the ED, shows contrasting results with previous ambulatory-based analysis as MPV was found to be higher in patients with VTE differently from our population. Conclusion: Even though we found some correlations between full blood count parameters and VTE as possible diagnostic and prognostic factors, further studies are needed before being considered valuable elements for clinical practice.


Marco REPETTO, Dr Stefano SARTINI (Genova, Italy), De Mattei LAURA, Altomonte FIORELLA, Paolo MOSCATELLI
08:30 - 17:40 #11674 - Full trauma team activation criteria in university hospital emergency department.
Full trauma team activation criteria in university hospital emergency department.

The high importance of full trauma team readiness upon arriving of severely injured patient is well known. However, indicators of full trauma team activation are different and depending on local trauma protocol.

We routinely use a pre-hospital ambulance team information about trauma mechanism as main criteria for full trauma team activation prior to patient arrival and define patient with Injury Severity Score ( ISS) 17 or more as severe injured victim. The aim of this research was to  improve full trauma team activation criteria to avoid its activation for minor trauma victims. We made a retrospective analysis of 293 trauma cases, when full trauma team was activated in Riga East clinical university hospital Emergency department during 6 months ( January-June, 2016).

53 patients ( 18, 1%) out of 293 were with ISS 17 or more, 240  ( 81,9%) were with ISS score less than 17.  92 patients ( 31, 4%) were female and 201 ( 68, 6%) male. 190 ( 64, 8%) patients were referred to the Emergency department bu ambulance team after road accidents, 28 ( 14, 7%) of them were with ISS 17 or more. Falls from high was second common trauma mechanism – 84 victims ( 28,7%), ISS 17 or more was 22 ( 26, 1%). In 19 cases trauma mechanism was with minor energy or unknown, 3 of them were with ISS score 17 or more.

From 240 patients with ISS less than 17, 86 ( 29, 4%) even with potentially high energy trauma had ISS score 0; 117 ( 39, 9%)  victims were with ISS 1-10, 37 ( 12, 7%) patients with ISS 11-16.

12 patients were dead within few hours , 8 of them with ISS 17 or more.

126 cases out of 293 were selected for Revised Trauma Score ( RTS) analysis. Patients transferred from lower level hospitals as well as patients with unknown all physiological parameters during primary survey were excluded.  91 patient (72.2%) had RTS 12 and  13 of them with ISS 17 or more, 20 patients ( 15, 9%) had RTS 11 ( 7 of them with ISS 17 or more), 13 patients were with RTS 3-10 ( 7 of them with ISS 17 or more) and 2 patients had RTS <3 ( both of them with ISS less than 17 and were dead within few hours).

Conclusion: even potentially high-energy trauma mechanism itself as well as Revised Trauma Score is not enough criteria for full trauma team activation. We therefore recommend both as more precise tool, and this information should be asked from pre-hospital ambulance team, to improve effectiveness of using human and financial resources. 


Karlis OZOLINS (Riga, Latvia), Aleksejs VISNAKOVS, Sarmite VILLERE
08:30 - 17:40 #11550 - Future tech: new devices and products in emergency care.
Future tech: new devices and products in emergency care.

New products promising the world to patients and providers are coming to market constantly.  Differentiating between what will work or has promise from what’s just a fad can be difficult.  This session will introduce a number of new devices and technologies relevant to emergency medicine with a focus on solutions that hold the promise of improving quality and outcomes, operational efficiency, cost effectiveness or the patient experience as well as innovations currently in the development phase that hold the potential to disrupt emergency medicine.


Manuel HERNANDEZ (Chicago, USA)
08:30 - 17:40 #11793 - Gender Analysis of General Disaster Preparedness Belief.
Gender Analysis of General Disaster Preparedness Belief.

Introduction: It is essential to identify people who are more vulnerable to disasters and why? What capacities are needed to be developed and strengthened and what services are needed? Gender analysis is essential to ensure appropriate response. The aim of this study was to compare general disaster preparedness belief based on gender.

Methods: The questionnaire consisted of validated scales assessing general disaster preparedness belief using the Health Belief Model and was administered to a convenience sample of 973 people in Yalova, Turkey. Questionnaires were self administered. Independent sample t test were applied to analyse the data. This study (Project Number: 2015/BAP/125) was supported by Research Fund of the Yalova University.

Results: Women (mean: 3.81) have significantly higher perceived severity subscale rates as compared to men (mean: 3.64) at p (t test: -4,628, p<0.001). ‘’The idea of disasters scares me’’ which is one of the items of this subscale was significantly higher in women (mean: 3.83) as compared to men (mean: 3.39) (p<0.001). For self efficacy subscale, men (mean: 3.96) have significantly higher rates as compared to women (mean: 3.61) (t test: 9,768, p<0.001). ‘’I can fix the furnitures that need to be fixed at home’’ which is one of the items of this subscale recorded significantly higher rates in men (mean: 3.86) as compared to women (mean: 3.52) (p<0.001). There was no statistically significantly difference between gender and the other Health Belief Model subscales.

Conclusion: The study highlighted on the gender differences of perceived severity and self-efficacy as it relates to general disaster preparedness. Intervention programmes could be based on a gender approach. 


Ebru INAL, Kerim Hakan ALTINTAS (Ankara, Turkey)
08:30 - 17:40 #11499 - Gender differences in presentation and management in patients with syncope.
Gender differences in presentation and management in patients with syncope.

Introduction:

Syncope is a major health care problem that accounts for many emergency departments (ED). Syncope affects both men and women. There are several predisposing factors and etiologies that favor the onset of syncope.

Objective: The aim of our study was to compare the incidence, risk factor, etiology of syncope between genders.

Methods:

Prospective, observational study over four years. Inclusion of adult patients admitted to the ED with a diagnosis of syncope. Exclusion criteria: no consent, neurological deficit suggestive of stroke, previous recruitment into the study, collapse related to alcohol consumption, trauma, or seizure activity. A physical examination, an electrocardiogram (ECG) and an orthostatic hypotension test were performed. Patient’s management was based on the EGSYS (evaluation of guidelines in syncope study) score.  All patients were explored in the cardiac unit. The final cause of the syncope has been determined after investigations.

 

Results: Inclusion of 245 patients: 157 (64 %) men and 88 (36 %) women. Mean age: 50 ± 19 years. Compared with men, women were generally older (52 vs 50 years) ,more likely to have a history of diabetes mellitus (22 vs. 20%) , hypertension (34 vs. 28%) and vavulopathy (2 vs. 0.6%),but  had lower prevalence of known rhythm disorder (4 vs. 5%) and cardiopathy (7 vs. 14%). The clinical presentation before syncope in women was dominated by palpitation (28 vs. 11%, p=0,002).   The ECG was normal in 62% of women vs. 56% in men. Women had lower prevalence of ventricular hypertrophy (1 vs. 7 %, p=0.05), bradycardia (0 vs. 8%, p=0.005) and heart infraction (0 vs. 3 %, p=0.05) in ECG. There was no difference in heart rates and EGSYS score. Syncope reflex and recurrent syncope were more frequent in women (37 vs. 27%) and (17 vs.14%) respectively.

 

Conclusion:

In our study, women were older and more symptomatic. Syncope reflex and recurrent syncope were more frequent in women than in men.


Hanen GHAZALI (Ben Arous, Tunisia), Morsi ELLOUZ, Sana TABIB, Ines CHERMITI, Ihsen HNEN, Najla ELHENI, Mahbouba CHKIR, Sami SOUISSI
08:30 - 17:40 #11677 - General characteristics of drowning episodes in Galicia.
General characteristics of drowning episodes in Galicia.

Introduction and objective

Despite the improvement in the prehospital emergencies systems, drowning remains as the third leading cause of unintentional injury death worldwide, accounting more or less, the 7% of all injury-related deaths. Children, males and individuals with increased access to water are most at risk of drowning. We present the incidence and characteristics of drowning in Galicia a community surrounding by the sea and with a high scattered population.

Methods

Descriptive study of the characteristics of drowning episodes in Galicia along 12 months. We include all the cases including those who survived. Data include age, sex, final result (exitus or alive), time elapsed from the in-call registered in the Emergencies Coordination Centre (ECC) to the arrival of the ambulance, and if possible identified cause. Data are presented as n and percentage.

Results

Along the 12 months of the study 52 episodes of drowning were registered. Of them 40 (76,92%) were men, median age was 59 years (range 7-86 years), mean time elapsed from the in-call at the ECC to the arrival of the ambulance was 37’39’’ minutes. Of the 17 (32,7 %) victims died, 12 (70,59%) were men. Median age of death was 62 years (range 17-87 years), mean time elapsed from the in-call registered at the ECC to the arrival of the ambulance was 36’43’’ minutes. The most frequent aetiology was the attempt of suicide, followed by loss of consciousness and dyspnea. No significant differences were found between the characteristics of victims who died and those who survived.

Discussion

Drowning remains as a frequent cause of death in developed countries, in our data, no differences regarding age, sex and aetiology (except attempt of suicide) between victims who died or not were found. In addition to a registry of drowning, global strategies regarding surveillance in pools or beaches, must be developed to diminish the incidence of death related to drowning.


Jose FLORES-ARIAS (santiago, Spain), Antonio RODRIGUEZ-RIVERA, Gabina PEREZ-LOPEZ, Olga DOSIL-DIAZ, Emilia PEREZ MEIRIÑO, Manuel BERNARDEZ OTERO, Antonio IGLESIAS VAZQUEZ
08:30 - 17:40 #11798 - General Disaster Preparedness Belief Scale Using the Health Belief Model as a Theoretical Framework: Reliability and Validity Measures.
General Disaster Preparedness Belief Scale Using the Health Belief Model as a Theoretical Framework: Reliability and Validity Measures.

Background and Objective: Disaster preparedness efforts focus predominantly on human behaviors. The study aims to develop and test the psychometric properties of the Health Belief Model in relation to general disaster preparedness belief.

Methods: The study was conducted in the city of Yalova among university staff in a Turkish University. A study group of 286 academic and administrative staff completed a Health Belief Model scale instrument containing 60 items covering issues related to general disaster preparedness belief. Exploratory Factor Analyses was used for the psychometric evaluation and reliability was assessed using item–total correlations and Cronbach’s alpha coefficients using SPSS 19.

Results: The Exploratory Factor Analysis extracted six factors that jointly accounted for 59.2% of variance observed namely; Self efficacy (8 items), Cues to action (5 items), perceived susceptibility (6 items), perceived barriers (6 items), perceived benefits (3 items) and perceived severity (3 items). Cronbach’s alpha coefficient for the subscales ranged from 0.90 to 0.74.                        

Conclusion: The Health Belief Model scale for general disaster preparedness belief was found to be a valid and reliable tool. Findings from this study can be used to guide intervention aimed at informing and educating people about disaster preparedness. 


Ebru INAL, Kerim Hakan ALTINTAS (Ankara, Turkey)
08:30 - 17:40 #11797 - General Disaster Preparedness Beliefs: The Example of Yalova University.
General Disaster Preparedness Beliefs: The Example of Yalova University.

Background: Disaster preparedness reduces vulnerability, increases mitigation level and is one of the basic component of disaster risk reduction. This study aimed to identify socio demographic and disaster related factors associated with general disaster preparedness belief using the Health Belief Model as a theoretical framework.

Methods: The study was a cross sectional study conducted in Yalova, Turkey. A study group of 286 academic and administrative staffs completed a HBM scale instrument. The questionnaire consisted of validated scales assessing general disaster preparedness belief using the Health Belief Model. The general disaster preparedness belief score was computed by summing up the six Health Belief Model subscales such that a higher score indicated a higher positive general disaster preparedness belief. Multiple linear regression were used to test for association between general disaster preparedness belief score and associated factors.

Results: General disaster preparedness belief score was positively associated with; higher monthly income, higher occupational status, ever experienced any disaster and having any emergency/disaster education. Respondents who had any emergency/disaster education had on an average 19.260 general disaster preparedness belief score as compared to respondents who had not had any emergency/disaster education (B=19.260±4.841, p<0.001).

Conclusions: Monthly income, occupational status, ever experience of any disaster and received any emergency/disaster education were important factors associated with general disaster preparedness belief. Interventions aimed at increasing general disaster preparedness should include provision of disaster education and should target individual with lower socioeconomic status. 

 


Ebru INAL, Kerim Hakan ALTINTAS (Ankara, Turkey)
08:30 - 17:40 #10837 - Generalized erythema multiforme and hemodynamic instability in a 76-year-old patient treated with levofloxacin and clindamycin. Steven Johnson Syndrome.
Generalized erythema multiforme and hemodynamic instability in a 76-year-old patient treated with levofloxacin and clindamycin. Steven Johnson Syndrome.

A 76-year-old patient with a personal history of amoxicillin-clavulanic intolerance, arterial hypertension, iron deficiency anemia, and gonarthrosis.

Usual treatment: omeprazole 20 mg / 24 hours, acetylsalicylic acid 100 mg / 24 hours, candesartan 16 mg / 24 hours, sertraline 100 mg / 24 hours

The hospital emergency department was transferred from the geriatric center to the generalized erythemorescence lesions of 48 hours of evolution, which had developed morphically in the last 24 hours, accompanied by febrile syndrome, decreased consciousness and increased dyspnea with use of accessory muscles.

Four days prior the patient had been assessed in the emergency department for decompensation of heart failure per respiratory infection, starting treatment with levofloxacin. Clindamycin is not added to the geriatric center because there is no improvement at 72 hours.

Physical examination at admission

Poor general condition, tachypneic, feverish. Conscious with tendency to sleep.

Blood pressure: 80/40, heart rate 180lpm, oxygen saturation 90% with 100% oxygen reservoir

Erythema- generalized desquamative predominance in genitalia and flexion regions with positive Nikolsky sign. Desquamation and ulcerous lesions on the mucous membranes (tongue, anus and labia majora).

Cardiopulmonary auscultation: rhythmic tachycardia without murmurs, vesicular murmur preserved with bibasal crackles.

Abdomen: globulous, soft and depressible without masses or megalias, negative blumberg, negative Murphy, fist negative percussion

Lower left limb: increased diameter with positive fovea to middle third.

Supplementary tests:

Blood analysis: hb 13,100, leukocytes 25,700 (92.2% neutrophils, 3.65 lymphocytes) Platelets 224,000, TP75%, glucose 224, creatinine 1.62 Total bilirubin 0.3, Na 144, K 4.1 Cl 103, PCR 135.

Chest x-ray: increased cardiothoracic index with increased vascular redistribution. Bilateral pleural effusion

EKG: atrial flutter at 190 bpm without alterations of repolarization.

During admission to the critical area, perfusion of amiodarone and magnesium sulfate are initiated, reverting to sinus rhythm. It is canalized via central venous femoral right is initiated fluid therapy, antithermic treatment.

Assessed by dermatology confirming Steven Johnson syndrome.

Valued by intensive care unit that enters the patient until hemodynamic stability and derivation after plastic surgery unit.

During stay in intensive care area the patient persists with hemodynamic instability presenting atrial fibrillation with 140lpm, sustained hypotension, and anuria. The family decides limitation of therapeutic effort and the patient dies within 24 hours of admission.

 


Cristina FERNANDEZ- FIGARES MONTES, Rafael INFANTES RAMOS (Málaga, Spain), David NUÑEZ CASTILLO, Manuel AGUILAR CASAS, Ivan VILLAR MENA, Jose Ignacio VALERO ROLDAN
08:30 - 17:40 #11813 - German Manchester Triage System: referral of non-urgent patients to a panel practice.
German Manchester Triage System: referral of non-urgent patients to a panel practice.

Title

German Manchester Triage System: referral of non-urgent patients to a panel practice

Authors

Bösl E., Möller J., Kill C., Hofmann A., Jerrentrup A.,

 Introduction

The Manchester Triage System (MTS) was devised to categorize patients in emergency departments (ED) according to medical urgency based on symptoms: immediate (red) to non-urgent (blue). Patients categorized as non-urgent should be seen by an emergency physician within four hours. The original MTS was adapted for Germany. In the German MTS 34 of the 50 triage algorithms offer a referral option for non-urgent patients. They can be referred to a panel physician i.e. a general practitioner who is a member of the Association of Statutory Health Insurance Physicians. According to a survey by the German Hospital Federation in 2015 one third of patients presenting to an ED could be seen by a panel physician instead. 

Methods

All patients who presented to the ED of a German university hospital on their own initiative between January 1st and December 31st, 2016 were evaluated retrospectively.  They were triaged in keeping with the German MTS. All patients categorized as non-urgent and with referral options to a panel practice were selected for further evaluation.

Goals of this study were: 1.) To detect the true referral rate among the patients evaluated 2.) To find out whether the diagnostic tests performed in the ED could have been performed by a panel practice instead.

Results

In 2016 a total of 20974 patients presented to our ED on their own initiative.

1879 of these patients were triaged as non-urgent i.e. MTS category blue.

994 of these patients could have been referred to a panel practice according to German MTS algorithms.

319 patients could not be included in the study for various reasons e.g. the patient left before being seen.

The data of 675 non-urgent patients with referral options were evaluated in our study.

317 (47%) patients were in fact referred to a panel physician.

358 (53%) patients underwent diagnostic tests and treatment in the ED, which could not have been provided by a panel practice. These tests included blood tests, radiographic imaging, endoscopies, ophthalmologic examination to mention but a few.

The diagnostic tests revealed pathological findings directly related to the presenting complaint in 225 non-urgent patients i.e. 63% of the 358 patients where referral was possible but not made.

Conclusions

Although German MTS algorithms provide options for referring non-urgent (MTS blue) patients to panel physicians, the actual referral rate is low.

In the majority of non-urgent patients, who were not referred from the ED to a panel practice diagnostic tests yielded pathologic results.

 


Elisabeth BOESL (Marburg, Germany), Johannes MÖLLER, Clemens KILL, Angelika HOFMANN, Andreas JERRENTRUP
08:30 - 17:40 #11896 - Getting back to family after 20 years.
Getting back to family after 20 years.

Background

An unidentified woman, about 45 years old, who suffers from mental illness, was taken from the street by an ambulance. The woman, who hardly cooperated, presented cough and dyspnea. She was living on the street, having no home.

 

Methods

The ambulance took her to Arad Emergency Department, where she was consulted. The final diagnosis was Respiratory Distress, Pneumonia and thus, she was given specialized treatment. The social nurse succeeded in communicating with the patient paying much effort. That social nurse asked for police involvement.  All of these led to the identification of the patient’s personal data and, furthermore, to finding her family, who was living in Deva, 150 km away from Arad. The woman lost contact with them 20 years ago and since then she had been missing.

 

Results

The implication of the social nurse from Emergency Department solved the social problem of this patient, who was warmly welcomed by her family after missing for 20 years.

 

Discussion

Without the implication of the social nurse, the emergency physician was able to solve the medical problem of the patient, but not the social problem that is also of a high importance.


Monica PUTICIU, Mihai GABRIAN (Arad, Romania), Monica MARC, Siminica DRAGOMIR, Codruta HALMAGEAN
08:30 - 17:40 #11502 - Giant left atrial myxoma: a case report.
Giant left atrial myxoma: a case report.

Introduction:

Cardiac myxomas are the most common forms of primary heart tumors. Its location may be life threatening. In 50% of cases, the diagnosis is made at the complication stage and 10% of the patients are completely asymptomatic. Transthoracic and transesophageal echocardiography allow diagnosis with sensitivity close to 100%.

Case:

We report the case of a 38-year-old-male patient with no past medical history, who presented to the emergency department for stage III NYHA dyspnea with progressive aggravation for six months associated with hemoptysis. He was hemodynamically stable with a blood pressure of 123/87 mmHg and a regular pulse rate of 80 beats/min. The cardiac auscultation revealed a diastolic rolling at the mitral focus, of intensity 4/6. Chest x-ray showed an enlarged cardiac silhouette with a cardio-thoracic index at 0.7. The electrocardiogram (ECG) was normal. Echocardiography showed a dilated left atrium containing a pedunculated mass of 16.4 cm2, heterogeneous with irregular surface, appended to the atrial surface of the anterior mitral valve and not movable with a subtotal obstruction of the mitral orifice during the diastole. The systolic ejection fraction was 62%. Mitral insufficiency of 2st grade. The systolic pulmonary pressure was elevated to 55 mmHg. The patient was transferred to cardiovascular surgery and underwent emergency surgery. Histological examination confirmed the diagnosis of myxoma of the left atrium. The surgical sequences were complicated and the patient died at seven day from a septic shock.

 Conclusion:

The myxoma can induce dramatic symptomatology and involve the patient's prognosis. Surgical treatment remains the only therapeutic option.


Hanen GHAZALI (Ben Arous, Tunisia), Ahmed SOUYAH, Asma BEN ALI, Anware YAHMADI, Mouna GAMMOUDI, Ahlem AZOUZI, Monia NGACH, Sami SOUISSI
08:30 - 17:40 #11871 - Giant Osborn t waves in patient with hypothermia and fatal evolution.
Giant Osborn t waves in patient with hypothermia and fatal evolution.

Introduction:

Hypothermia is a critical medical emergency which can be life-threatening by leading to heart failure and death. It is often associated with electrocardiogramm changes explained by the decreasing of the temperature. Atrial ectopic activity is often noted and can progress to malignant arrythmias. At this level of hypothermia, 80% of patients have Osborn waves that consist of an extra deflection at the end of the QRS complex. They are also known as late delta waves, camel-hump waves, and hypothermic waves.

Case report:

We report the case of a 50-year-old young male, a smoker and alcohol consumer, with no other medical history, who lives alone. He was brought to the emergency department by after he was found unconscious in an attic. On examination: the patient had a Glasgow coma scale of 9 with no neurological signs of localization and a blood glucose level of 5,6 g/l. No visible marks of trauma were visible but he had compression points of the left body (face, shoulder, elbow, knee). The temperature was not measurable (deep hypothermia) with cold extremities. The blood pressure was = 44/22 mmHg with a regular bradycardia  of 44 bpm. The ECG showed a sinusal bradycardia with generalized Osborn waves. The patient  was monitored on the emergency resuscitation room , warmed,optimization of the circulation was immediately fulfilled with  isotonic serum and early cathecholamines introduction (Norepinephrine) were introduced.Unfortunaltely,  the evolution was rapidly marked by a cardiovascular collapse and cardiac arrest with failure of any resuscitation  prolonged attempts.

Conclusion :

Although the arrhythmogenic implications of the Osborn waves are not fully understood, the existence of this characteristic deflection may represent some underlying critical conditions. This EKG finding is rare to detect and must lead the physician to suspect critical hypothermia and anticipate the possibility of cardiac arrest. Unfortunately, in our case report the evolution was fatal, hypothermia is considered one of the reversible causes in cardiac arrest and may lead to prolonged resuscitation.


Imen MEKKI (Tunis, Tunisia), Hamed RYM, Mohamed KILANI, Bellili SARRA, Ahmed SOUYAH, Abderrahim ACHOURI, Maroua MABROUK, Chokri HAMOUDA
08:30 - 17:40 #11455 - Hand lacerations: from clinical exam to intraoperative findings.
Hand lacerations: from clinical exam to intraoperative findings.

Introduction

Hand lacerations are commonly seen in the emergency department. Misdiagnosed or underestimated injuries can have significant impact on hand function.

Background

A first 3 months retrospective study was performed in our center in 2011 including all patients with simple hand lacerations, surgical exploration was provided to 104 patients, 41% had non organ injury.

The aim of the study was to compare accuracy of clinical examination by emergency physician and intraoperative findings.

Methods

The prospective cohort study was conducted during a 5 months period in our center.

We included all consecutive patients presenting with simple hand laceration. Excluded were patients with complex injuries, amputations, fractures, and ischemia.

We used questionnaires completed by emergency physicians describing the laceration and the suspected injury and we compared it with the surgical examination and the operating reports.

Results

25121 patients presented to ED during the study – period. 250 had simple hand laceration (1%): men 171 (68.4%). The mean age was 33 year old (15-92). 175 (70%) were right-handed. The weak hand was injured in 42% and twice in 0.8%. 55.2% of the wounds were located at the palmar face and 68% on fingers. 32% were occupational accident. 100 (40%) were treated by emergency physician (distal, superficial wound), 150 were oriented to a hand surgery team, 94 were undertaken at our hand unit.

Complete data were achieved in 51 patients, 2 patients hadn’t surgery after surgical examination.

Emergency physician suspected extensor tendon injuries in 32.7%, flexor tendon injuries in 20.4%, nervous lesions in 22.5%, articular damage in 26.5%, tendon sheath injuries in 26.5% and vascular lesion in 2% of patients.

Intraoperative findings were extensor tendon injuries in 26.5%, flexor tendon injuries in 22.5%, nervous lesions in 22.5%, articular damage in 18.4%, tendon sheath injuries in 18.4% and vascular lesion in 2% of patients

34.7 % had no deep injury.

The sensibility of emergency physician’s evaluation was 90.6%, there was no significant difference with the surgical exam (p = 0.35), the specificity was respectively 29.4% and 58.8% after emergency and orthopedic examination.

The positive predictive value to detect a vascular or nervous lesion was respectively 54% and 55% and the negative predictive value was 84 and 88% after emergency physician’s evaluation.

Discussion

In our center, only hand lacerations with no vascular, neurological or nervous deficit, superficial lesion are undertaken at emergency department. The wound bed must be seen before stitching. All the other patients are referred to the surgical team.

Conclusion

The clinical findings are an important part of assessment of a patient with hand laceration. Misdiagnosed damage structure can have consequences for hand function. Physicians must be able to suspect penetrating lacerations and refer patients to the surgical team.


Dr Christelle HERMAND (Paris), Clement TOURNON, Simon LEMBERGER, Vincent LASNE, Nicolas CURY, Dominique PATERON
08:30 - 17:40 #11039 - Has the full moon an influence on admissions in Emergency Department?
Has the full moon an influence on admissions in Emergency Department?

Introduction

Among Emergency Department (ED) teams, there is a popular belief that the lunar would influence patient flow and that full-moon periods would make ED busier.

Methods

To investigate this relationship, we led a retrospective bicentric study during 3 years on ED admissions in two urban teaching hospitals in France during 3 years (01/01/2013-31/01/2015). Full moon and new moon were defined as 3-days periods according to the astronomic definition of the synodic period of revolution of the moon. An analysis of the day of the week was also led, in order to avoid biais of analysis.

Results

A total of 1095 days and 347,187 admissions in Emergency Department were analysed. 111 days were considered as full-moon days according to the astronomic definition. Among those ones, 7,352 were admitted in a resuscitation room and 126,042 were walk-in consultations. In total, during the period, 119,705 patients were admitted in another service of the hospital. Our study found no significant difference on total ED admissions between full-moon days (317.6 ±31.8) and other days (317.0±30.9) (p=0.73). Neither resuscitation room admissions (6.4±3.1 vs. 6.7±3.4, p=0.41), nor walk-in consultations (112.5±21.6 vs. 115.4±22.4, p=0.24) were significantly different, between full-moon days and other days. No difference was nor observed in hospital admissions between full-moon days (110±15) and others (109±14.4) (p=0.20). In the literacy, the most part of statistical analysis of data did not exhibit a positive relation between full-moon days and increasing of trauma patient admissions in the ER, nor psychiatric disturbance. It is notable that previous studies exploring this belief -that full-moon has an influence on patient admission in the ED- have been lead in different countries all over the world, demonstrating this superstition is not peculiar to occidental cultures.

Conclusion

Our study showed no difference on patient flow between full-moon days and others.

 

 

 


Quentin TOURON, Sarah UGÉ (Strasbourg), Alicia THIERRY, Sébastien BERGERAT, Céline RENFER, Nabil TELITEL, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11246 - Health expert for the EU Civil Protection Mechanism, Hurricane Matthew, Haiti, October 2016.
Health expert for the EU Civil Protection Mechanism, Hurricane Matthew, Haiti, October 2016.

General situation: Civil protection consists of governmental aid delivered in support of a nation to best adjust in the immediate aftermath of a disaster for the protection of people and property. It can be in-kind, by sending teams specialized in crisis management or for on-site assessment and coordination. The European Union (EU) Civil Protection Mechanism was established in 2001; it aims to facilitate cooperation and the pooling of national resilience drivers in order to increase the relevance and the efficiency of the response to the crisis between 32 European countries. It can be activated upon request by any country in the world. The selection of specialists is national, to be accredited by the EU. The missions are of great complexity, with high responsibility at the international level, like their intensities, in the uncertainty of the first moments of the crisis, of people and institutions involved.

Mission: On 4 October 2016, hurricane Matthew devastated the western part of Haiti, with the government urging the EU to activate the EU Civil Protection Mechanism. A team of five experts, including one health expert, was put in place from 7 to 26 October for the European Commission. The missions mainly included facilitating the coordination, deployment, provision and withdrawal of aid received by Haiti from EU member states, supporting national authorities and the United Nations in assessing the situation and facilitating coordination, identifying needs and the type of assistance needed in civil protection and formulating recommendations. This was particularly in favor of the largest water treatment unit of French origin, the Civil Protection Training and Response Units (UIISC), distributing kits tailored to national stocks in the fight against severe acute diarrhea outbreaks in close collaboration with the World Health Organization having government mandate pertaining to health issues.

Discussion: The health expertise was unique in assessing and anticipating the different aspects of the health crisis, formalizing EU health offers as closely as possible to the needs and making immediate use of them, the expertise of the regional hospital of the city of Jeremy for an immediate resumption of its surgical activity. The adjustments of the health expert must be very dynamic in regards to the crisis management,  in collaboration with the various local, French, European and international partners.


Hugues LEFORT, Alexandre ALLONNEAU, Dr Abdo KHOURY (Besançon), Sandy EPIPHANIE, Rémi BREYSSE, Marie-Thérèse FERLET, Jérôme BORDARCHAR, Michel BIGNAND, Jean-Pierre TOURTIER
08:30 - 17:40 #11613 - Health impact of Euro 2016: A medical response to be organized.
Health impact of Euro 2016: A medical response to be organized.

During EURO 2016 tournament, which occured from June 10th to July 10th of 2016 in France, the hosting cities had set up some designated Euro 2016 areas called Fanzones. The “Champ de Mars – Tour Eiffel” Fanzone which can be up to 92000 supporters were located next to the Georges Pompidou European Hospital (HEGP). In this study, data on emergency department (ED) visits were analyzed during this period to find if there is an impact with this influx of supporters on the emergency department.

This is an observational study from June 9th to july 11th of 2016 with a chart review of all the patients from a Fanzone admitted at the emergency department of HEGP.

129 patients were included, 87 (67.4%) were transported to the ED, a majority of men (75%), 116 patients had a medical consultation. The most common injuries were traumas (34.8%) and lacerations (18.6%). 2 patients were hospitalized.

There was a significant increase in attendances during the tournament when the daily temperature was more than 23°C OR=16.86 [4.5-75.7] p=0.01, when it wasn’t a home nation match OR= 0.15 [0.02-0.72] p=0.02, when the football game occured in Paris OR=6.69[2.30-21.5], and when it was a Saturday or Sunday OR=3.85 [1.16-13.3] p=0.02.

A significant increasing attendance was observed on the emergency department of HEGP during the tournament.  It could be necessary to discuss special measures for increased workload during such a mass event.


Sylvie HO (Puteaux), Sophie JUMEL, Richard CHOCRON, Philippe JUVIN
08:30 - 17:40 #11973 - Heart Failure in ED: Collaborating to make cardiogy best practice fit ED workflow.
Heart Failure in ED: Collaborating to make cardiogy best practice fit ED workflow.

Background

Noting that chronic disease (CD) account for 2/3 of medical admissions and approximately 80% of all healthcare costs, the Irish Health Service has an initiative to improve integrated care for CD. However, since less than 1/4 of ED presentations are admitted - often ED assessment and intervention are not part of integrated care, this is especially true for heart failure (HF). Currently also, most ED's work to a 4-hour target from time of patient presentation to disposition. The European Society of Cardiology (ESC) have issued guidelines for the management of HF which, while comprehensive, at a practical level are not used in our ED.This study is part of an ongiong project that has identified a set of 100 HF-related ED presentations that physicians found particularly challenging. Of these, 30% were de-novo HF diagnoses, 63% were referred for admission.The commonest HF-related challenges to ED workflow were: 

(1) lack of explicit admission criteria partcularly in non-critically ill patients
(2) lack of guidance in therapy for discharges, particularly in the context of renal failure.
(3) lack of access to timely follow-up cardiology particulalry for de-novo diagnoses. 

This study aims to distill ESC-HF guidelines to a pratical tool that fits the ED 4-hour target.


Methods

A group of ED physicians and cardiologists reviewed the 2016 ESC-HF guidelines, categorising these into actions that could be taken within goal times of : 30 minutes, 2 hours and 4 hours from ED presentaion. This checklist was applied retrospectively to the 100 challenge cases. Specific dispositon criteria were defined for the 3 ED workflow challenges. 


Results

Concrete ED actionable items within the goal times were identified from ESC guidelines. When applied retrospecitvely to our 100 cases, ESC guidelines frequently lacked pratical advice to comprehensively address the 3 HF in ED workflow challenges. A set of evidence-based quality statements were identified from outside the field of cardiology, and agreed as standards to guide patient disposition. 


Discussion
The resulting HF acute management checklist is currently being implemented prospectively in our department. Initial feedback is positive: ED physicans report having more confidence when deciding dispositon, there is less ambiguity when general medical admitting teams are taking over care. ED physicians are more confident that interventions initiated in discharged patients will be followed-up in a timely manner. Cardiologists report being more confident that ED physicians are skilled footsoldiers in the front-line management of HF, despite this necessitating some increase in access to outpatient services.


Conclusions

(1) Distilling the ESC guidelines in to a functional care bundle that meets ED time constraints is possible.
(2) Evidence-based standards can be identified and agreed where ESC guidelines lack specificity. 
(3) This form of collaboration enables ED to play a leadership role in the integrated care of chronic disease. 




Dr Kelly JANSSENS (Dublin, Ireland), Rory O'HANLON, Nigel SALTER, Mark WILKINSON
08:30 - 17:40 #11990 - Heart rate at the enter of ER and after resting: outcome and risk stratification.
Heart rate at the enter of ER and after resting: outcome and risk stratification.

Abstract: 

Background: In emergency department, in order to recognize as soon as possible patients with severe conditions, heart rate in one of the common element used and we consider that a tachycardia represents a risk majoration. we usually measure it during the triage, when patient just arrived, with a risk of false tachycardia. So we wanted to know if heart rate control in a calmer situation may accurate our triage and better anticipate the patient outcome.

Methods: A prospective cohorte study was conduct in Saint louis emergency department Hospital. We included 207 patients related to traumatology or medicine. We measure their heart rate during the first triage and 5 minutes after been installed in the examination room. We compared it to the first triage and related it to the hospitalisation also.

Results: For all our 207 patients, there were 40 patients (19,3%) with a heart rate superior to 100/min in the first connect and only 14 patients (7%) during the new control.

Only one patient with heart rate more than 100/min at the enter and less after the control was hospitalized.

20% of patients with high heart rate at the enter were hospitalized (Versus 6% whitout tachycardia)

Half of patients who stay with high heart rate in the control were hospitalized.

95% of patients with tachycardia were classified at least in a level 3 in the triage scale,  and patient with confirmed tachycardia were classified in a high risk group since the enter.

Conclusion: Tachycardia is a good element for outcome and hospitalisation stratification but it can be a  even better one if we control it in better condition.


Carl OGEREAU (Paris)
08:30 - 17:40 #10957 - Heatstroke in runner.
Heatstroke in runner.

Clinical case:

Consultation motive:

34-year-old male who comes to urgencies for evanescence picture with alteration of the level of conscience, increase of temperature; 39ºc, sudoración profuse and warm skin after marathon career.

At the arrival to urgencies the patient finds with Glasgow 12 ptos sleepily with tensions arterial 110/56 FC 110 T 38.0th, sato 98 % (aa).

Personal precedents:

NAMC

NOT IQ

Infantile asthma

Habitual not treatment

Physical exploration:

Skin; sudoración profuse, flush and increase of temperature

NRL: conscious, disorientated, he answers to verbal and painful stimuli

AC: taquicardico

AP: MVC

ABD; I brandish and depresible, not painfully to the palpación

Complementary tests:

Venous Gasometría: Ph 7.35, Pco2 35, po2 80, hco3 24, lactic 0.8, na 131

Analytical: Leukocytes 7.0, Neutrofilos 80 %, Lymphocytes 22 %, Eosinofilos 10, glucose 180, Urea 60, sodium 135, CK 350

Thorax Rx:

Clear not condensations

Urinal sediment: without significant alterations

Orientation diagnoses:

Heatstroke in runner

Distinguishing diagnosis:

1) Other Hipertermias

2) Infections: Sepsis; Meningitis; Leptospirosis

3) Injuries of the SNC: Hemorrhage Hipotalámica; sharp Hydrocephalus; Convulsions

4) Endocrinopatías: Thyroid thunderstorm; Feocromocitoma

5) Delirium tremens.

Evolution:

After initiating cooling for physical methods with cold compresses (ice) of a continued way; especially in neck, armpits and English and use fans placed straight on the patient, Reposición: Physiological Saline whey or Ringer Lactato, in an entire quantity concerning 3000-3500 cc/día, with rhythm incial more intensive (250cc/hora), observed a progressive recovery of the patient so much physically like complementary tests.

The importance of the picture of heatstroke in runner owes to the increase of marathons and number of persons of all the ages that realize it increasingly in any place of the world and with the possibility of the achievement of a diagnosis and rapid treatment on the part of the medical equipment dealer.


German Jose FERMIN GAMERO (PALMA DE MALLORCAQ, Spain), Ricardo OLIVEIRA DA CUNHA, Julio OLSEN, Lara PUERTO, Bernardino COMAS DIAZ
08:30 - 17:40 #11480 - Helicopter Emergency Medical Service (HEMS) of Croatia.
Helicopter Emergency Medical Service (HEMS) of Croatia.

HEMS in Croatia is a service in development. Currently the HEMS is carried out in cooperation with the Croatian Ministry of defense in two bases. Those bases only cover the coastal region of the country provided only secondary missions. Croatia, as a modern EU country with a developed coast, islands and a continental zone, should have at least 4 to 5 bases which would be strategically distributed to cover the entirety of the territory inside a 20 min’ helicopter flight, or better said inside the ''golden hour'' of medical care. With Croatia's acceptance in the EU in 2013., the need to respect the legal obligation coming from the EU directive 965/2012 is implied. In 2015. an international public tender for the implementation of the ''HHMS RH'' pilot project with two bases was announced by the Ministry of health. The Italian tenderer group EliFriulia and AirGreen won the tender with two helicopters – the Airbus Eurocopter EC135 T2 and the EC 145 T2. The pilot project is carried out in the span of 4 months. Before the actual operational beginning of the project, the medical crew went through a demanding 10 days training process by EU standards. The medical technicians and nurses had an intensive education about the safe operation inside the helicopter and acquired an international license for HEMS TC by EASA regulations which is valid for 4 years, after which it has to be renewed. The doctors, while being introduced to the safety regulations inside a helicopter, also had additional improvement in aeronautical medicine. The medical technicians and nurses had a detailed familiarization with avionics, the devices inside the helicopter, meteorology, critical flight situation management, the usage of GPS and the usage of other navigational equipment. After the theoretical and practical teaching, a total number of 10 excellent teams was ready for the needs of a HEMS in Croatia. Inside the 4 months of operational flying, the two bases of the HEMS of Croatia had a total number of 219 interventions including primary and secondary flights. With the establishment of HEMS, a ''golden hour'' intervention of the Emergency medical service (EMS) is provided even for citizens of the less traffically connected locations in which there is no grounded EMS team or the estimated time of arrival of the EMS team is much too extended. This pilot project proved the need for the establishment of a HEMS on the entire Croatian area and the simple implementation inside the existing EMS network. After positive experiences of the pilot project, during the summer season 2016. is established in cooperation with Ministry of the Interior and Ministry of health HHMS base in Dubrovnik (LDDU) for southern Dalmatia. Ministry of the Interior has provided a helicopter EC 135 and flight crew. Ministry of health has provided those same educated teams HHMS (HEMS TC and doctors). Inside the summer season 2016. HHMS base Dubrovnik had a total number of 96 interventions.


Josko BILIC (Zagreb, Croatia), Damir VAZANIC, Maja GRBA-BUJEVIC
08:30 - 17:40 #11907 - Helicopter medical interventions in North-East Romania.
Helicopter medical interventions in North-East Romania.

Background: Helicopter emergency medical services (HEMSs) activities in our country have a history of about 20 years. The aims of this study are to gather information on HEMSs activities on the North-East Region of Romania in order to evaluate the importance of helicopter transport of patients with different pathologies in a region with a deficit of emergency specialists and to evaluate the rate of survival of those patients at 24 and 48 hours after transport by helicopter.

Methods: We performed a retrospective study on a period of 4 years (2013-2016) of the interventions by helicopter for patients in the North-East Region of Romania between January 1st 2013 and May 31 2016. North-East Romania has 30,949 km² and 3.84 million inhabitants. It was intervened with an MY 8 helicopter and a Eurocopter 135 helicopter, having mobile intensive care medical equipment, 2 pilots, 1 doctor and 1 nurse. The data collected were processed in SPSS Statistics 23.

Results: There were registered 1643 helicopter missions (84,96% adults, 12,72% childrens and 2,32% newborns); the proportion of primary vs secondary interventions was of 1:1. Earlier treatment and faster transport to hospital were the main reasons for benefit. Cardiac etiology (33%) and trauma (12%) prevailed in adult population, mostly of life-threatening severity, while for the pediatric population the main patholgy was represented by trauma (31,5%), burns (17,2%) or congenital diseases on newborns (63,1%). The most frequent therapeutic procedure was drug administration (72% of missions); endotracheal intubation occurred in 8,15% while 15% of patients were already intubated at the time of takeover by the helicopter medical team. Cardio-pulmonary resuscitation during the missions was necessary in 66 patients (4%). Overall mortality rates at 24 and 48 hours after the transport were of 2,9% and 4,4%. Specifically the mortality rate in patients with STEMI decreased from 13.4% to 8.19% all over Romania and to 7.9% in our region. The decisions to send the helicopter were taken on medical criteria according to the existing laws, the transfer time and the availability of the terrestrial emergency crew. The average distance to the site, measured by land, was 162 km, (34–250 km). The average time of transport by air was 36,01 ± 10,16 min compared to 104,3 ± 32,42 min estimated by land (p > 0.01).

Conclusions: The helicopter is a very important mean of transportation for patients living in either far or inaccessible by land areas. The helicopter transport of patients was associated with a lower overall mortality rates at 24 and 48 hours. The potential of reducing the times of transport in patients with critical medical conditions should make the helicopter the main way of transportation in areas with a deficit o physicians and long distances. 


Diana CIMPOESU (IASI, Romania), Tudor Ovidiu POPA, Mihaela CORLADE, Paul - Lucian NEDELEA
08:30 - 17:40 #10845 - Helicopter transport of rural major trauma patients is no better than ambulance.
Helicopter transport of rural major trauma patients is no better than ambulance.

Background: The benefit of helicopter (HEMS) transport of major trauma patients remains controversial. We aimed to determine whether transport of major trauma patients from rural Western Australia (WA) by HEMS was associated with better outcomes than those by ambulance.

Methods: This is a retrospective cohort study of major trauma patients transported from rural areas to Royal Perth Hospital (RPH), the only trauma centre in WA, by HEMS or ambulance from 1997-2015. Major trauma was defined as Injury Severity Score (ISS)>15. Rural areas were outside of the Perth Greater Capital City Statistical Areas as determined by the Australian Bureau of Statistics. Patients with penetrating trauma were excluded (n=7). The trauma registry at RPH was used to identify eligible cases. We used data from St John Ambulance Western Australia, a HEMS operator and road ambulance provider in WA, to obtain the location where the first HEMS/ambulance was dispatched and the time of the first call. Patients were divided into four groups: direct transport from rural areas to RPH by ambulance (direct AMB) or by HEMS (direct HEMS), interfacility transport from a rural hospital to RPH by ambulance (indirect AMB) or HEMS (indirect HEMS). The primary outcome was in-hospital mortality and the secondary outcome was length of stay (LOS). The outcomes were compared using logistic and linear regression analyses adjusted for age, sex, ISS, time and distance to RPH, the presence of major traumatic brain injury (TBI) (Abbreviated Injury Scale of head≥3) and other confounders after multiple imputation. Direct ambulance was excluded from regression analyses due to small sample size.

Results: 542 subjects met study criteria with median ISS of 25 (inter quartile range [IQR] 19-33) and median distance to RPH of 131km (IQR 97-178). Seven and 281 patients were directly transported to RPH by ambulance and HEMS, and 145 and 109 were transferred from a rural hospital by ambulance and HEMS, respectively. Median time from call to arrival at RPH was the longest in indirect HEMS (268min, IQR 217-322) and shortest in direct AMB (170min, IQR 104-177). In-hospital mortality of indirect AMB (7.6%, 95%CI 3.2-12) was not significantly different from those of direct HEMS (6.8%, 95%CI 3.8-9.7) and indirect HEMS (17%, 95%CI 8.7-23). Patients in indirect HEMS had the highest proportion of major TBI (61%, 95%CI 51-70), and were significantly more likely to die than those in direct HEMS (adjusted odds ratio 3.3, 95%CI 1.4-8.0). LOS of indirect AMB (9days, IQR 5-17) was significantly shorter than that of direct HEMS (12days, IQR 7-24, p=0.02) and indirect HEMS (17days, IQR7-29, p=0.03).

Conclusions: Transport of rural major trauma patients by HEMS was not associated with lower mortality or shorter LOS than transport by ambulance. The highest prevalence of major TBI and/or the longer time to RPH may have contributed to the outcomes of indirect HEMS. Research is needed to investigate who benefits most from HEMS.


Hideo TOHIRA (Perth, Australia), Daniel FATOVICH, Rao SUDHAKAR, Paul BAILEY, Teresa WILLIAMS, Judith FINN
08:30 - 17:40 #11211 - Hemoptysis after fibrinolysis and treatment with ticagrelor.
Hemoptysis after fibrinolysis and treatment with ticagrelor.

Male 47 years old, former smoker, rheumatic fever, bacterial pericarditis. Ischemic heart disease (NSTEMI), severe disease of two arteries revascularized with stents (left anterior descending and left circumflex artery   ) with posterior reestenosis of both arteries requiring CABG. Treatment: torasemide, AAS, atorvastatin, ramipril, bisoprolol, pantoprazole, diazepam and ticagrelor (suspended days before) and replaced with ivabradine. He starts after leaving the gym with right facial paralysis, dysarthria and right hemiplegia without loss of consciousness. He was attended by extra hospital ambulance staff and they activated Code Ictus. It is a special code when the sanitary recognize symptoms of ictus to improve the assessment to these people first taken to the hospital as soon as possible and once there, with the images test and treatment.Exploration: conscious, right oculocephalic deviation, severe dysarthria, left hemianopsia by confrontation, left facial paresis, left hemiinatention, left hemiplegia,upper  left limb descerebration to pain and lower left  limb  1/5 after painful stimuli. Left extensor CPR and left hemihipoesthesia. (NIHSS 18). Cardiac auscultation : Smooth rhythmic tones, supraaortic trunks without blows. Distal symmetrical pulses. Complementary: CT scan CRANEAL hyperacute infarction in right middle cerebral artery territory. Blood analytics we highlight Hb 10; Glucose 113 and coagulation without alteration. Rx thorax: cardiomegaly, signs of HF. EKG: sinus rhythm, right bundle brunch block, R amputation in precordial, high T and V3-V4. Fibrinolysis begins with 7 mg bolus (79 kg) and perfusion at 5 minutes, starting with hemoptysis. Valued by ENT that excludes upper Airway bleeding, requiring bronchoscopy and admission to the ICU (self-limiting hemoptysis). During hospital admission, complete AngioCT scan  study: Complete right internal carotid occlusion; Catheterization Severe stent restenosis Left anterior descending  and Left circumflex .Echocardiogram: Severe aortic insufficiency with moderate systolic dysfunction. Aortic valve replacement / repair was decided after stabilization of the neurological picture. The high mild motor improvement of the Lower left limb him to ambulate with support, but complete pleura of the Upper left limb  persists, with treatment with double antiaggregation prior to cardiac surgery.Conclusion: Treatment with antiplatelet agents is a relative contraindication for fibrinolysis in ischemic stroke because of the risk of bleeding. Therefore, it is recommended to weigh the risk / benefit in patients with bleeding propensity, as well as the suspension of the drug 7 days prior to Elective surgery.


Marta JIMENEZ PARRAS (SPAIN, Spain), Maria Palma BENITEZ MORENO, Carlos DE LA CRUZ COSME, Eduardo ROSELL VERGARA, Maria Lucia MORALES CEVIDANES
08:30 - 17:40 #11875 - HEMORRHAGIC EVENTS IN PATIENTS WITH ATRIAL FIBRILLATION IN TREATMENT WITH ANTIAGREGANTS AND /OR ORAL ANTICOAGULANTS.
HEMORRHAGIC EVENTS IN PATIENTS WITH ATRIAL FIBRILLATION IN TREATMENT WITH ANTIAGREGANTS AND /OR ORAL ANTICOAGULANTS.

Introduction

Atrial fibrillation (AF) is the most common arrhythmia in clinical practice, about 25% of the world's population over 40 years  age will suffer it across their life. AF is associated with a high risk of thromboembolic complications, fundamentally stroke, and oral anticoagulants have shown their ability to reduce this risk. However, oral anticoagulants may cause a significant increase of the risk of bleeding complications.

Objective:

Analyze the prevalence of hemorrhagic events in patients with AF receiving antiplatelet and / or anticogulant therapy during six months after discharge.

 Patients & Methods:

Descriptive, observational and retrospective study in a General Hospital in Murcia (Spain), which manage a population of 200.000 people and 275 emergencies / day.  In the study 762 patients with AF from 1st October 2012 to 30th December 2013 were included. The analyzed variables are: average age, sex, anticoagulants or antiplatelet therapy and hemorrhagic events during 6 months after discharge. IBM® SPSS, version 21.0 was used as statistical program.

Results:

The sample under study was constituted by 64.59% women and 35.61% men, with an average age of 72 years. Only 22 episodes of major bleeding were observed during the six months after discharge. 5.38% of the 22 episodes received only antiplatelet therapy and 6% received oral anticoagulants. Concerning the antiplatelet drugs, it was observed that the hemorrhagic event was presented in 85.71% and 42.86% for the acidoacetylsalicylic and clopidogrel therapies respectively. The acenocumarol was presented in 71.42% out of the total bleeding patients treated with oral anticoagulants followed by ribaroxaban 35.71% and  in dabigatran 7.14%.

Conclusions

Despite the prevalence of major bleeding events in patients receiving antiplatelet and/or anticoagulant therapy in our study  is low, we should consider that they can cause a significant increase in the risk of major hemorrhagic complications. Therefore, it is essential to make a proper assessment of the benefit / risk using CHA2DS2-VASc risk stratification score and HAS-BLED bleeding risk score.


Maria Consuelo QUESADA MARTINEZ, Maria CORCOLES VERGARA, Fernandez-Camacho DANAE, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Blanca DE LA VILLA ZAMORA, Pascual PIÑERA SALMERÓN (montepinar, Spain), Blanca MEDINA TOVAR
08:30 - 17:40 #11646 - Hemorrhagic shock complicating a spontaneous retroperitoneal hematoma.
Hemorrhagic shock complicating a spontaneous retroperitoneal hematoma.

Background:

Spontaneous  retroperitoneal  hematoma  is  an uncommon  but  potentially fatal clinical  entity  that  rarely  occurs  in  patients receiving  anticoagulation  therapy , complicating most often renal angiomyolipoma rupture.

 

Case report:

We report a case of a 56 years old woman receiving anticoagulation for Atrial Fibrillation (AF), presenting to the emergency department for abdominal pain without fever. The patient was anxious, hemodynamically unstable with a rapid pulse, immeasurable blood pressure (BP) and a pale and cold skin. She had no signs of external hemorrhage but a pain in the right lumber region. Biological exams showed a low rate of hemoglobin (5,5g/dl) and reduced prothrombin time (PT= 3%) with elevated international normalized ratio level (INR=23) and a normal platelet count (PLQ=182000/mm3) without other abnormalities.

Abdominal CT scan showed a large retroperitoneal hemorrhage in the right psoas muscle (height= 25cm) extended to the root of the mesentery and pushing the right kidney and colon. The CT scan showed also a complicated angiomyolipoma in the right kidney. The patient received fluid resuscitation with normal saline, noradrenalin, prothrombin complex concentrate (PCC) at the dose of 25UI/kg and she got transfusion, with a favorable clinical and biological outcomes: BP=120/60 (MAP=65mmHg), Hb=8,5g/dl, PT=59%, INR =1,42 and no surgery was indicated. Two weeks after the retroperitoneal hematoma was completely resorbed.

 

Discussion:

Spontaneous retroperitoneal hematoma is an uncommon cause of hemorrhagic shock with a non-specific presentation that can lead to misdiagnosis, delayed treatment and may be thereby fatal.

 

 

 

 


Asma ALOUI (Tunis, Tunisia), Hana HEDHLI, Nader BEN OTHMEN, Rym HAMED, Salwa MANSOURI, Alaa ZAMMITI, Yasmine WALHA, Chokri HAMOUDA
08:30 - 17:40 #11085 - Herpes simplex type 2 encephalitis as a stroke mimic.
Herpes simplex type 2 encephalitis as a stroke mimic.

A healthy 72-year-old woman with no disability who woke up and underwent  holocranial headache and psychomotor agitation, followed by 1 minute self-limited tonic-clonic seizure. Patient recovered consciousness, witn weakness in left arm and leg. During his transfer to hospital she suffered two new seizures , Hospilary stroke code was activated on admission at the emergency room

Examination at admission: 37ºC temperature, sweaty, eupneic, well hydrated and perfused. Conscious oriented in time, space and person. He obeys simple and complex orders. Bradipsychic, dysarthric. Severe weakness of the left upper limb, central facial palsy, without motor or sensory alterations in other limbs. No other neurological déficits No meningeal signs.National institute of health stroke Scale (NIHSS) Score of 5.

Brain CT scan showed right temporoparietal hypodensity with small haemorrhagic transformation with out contrast enhancement. Blood test; Leukocytosis with neutrophilia, PCR 146  and Procalcitonin 2.93.

The patient had an right hemispheric syndrome, fever and seizures. Firstly the stroke hypothesis were thought, because the fast symptoms onset, in spite of fever and epileptic seizure. Stroke could produce infections and seizures.

Trombolitic treatment were not administered and Atraumatic lumbar puncture was perfomed with Clear cerebrospinal fluid (CSF): 13 Leukocytes (65% polymorphonuclear), 520 red blood cells, 70g / dL protein,  CSF glycemia 67mg/dL and Blood glycemia 83mg/dL). Polymerase Chain Reaction (PCR) was positive for herpes simplex type 2 in CSF). The patient was diagnosed with Encephalitis for herpes simplex type 2.

Fastly, intravenous acyclovir 10mg/kg every 8 hours and phenytoin were administered. The patient progressively improved during the admission in Neurology department. Hospital discharge was possible after one month of treatment. Patient became asymptomatic.

Encephalitis for herpes simplex is frequently produced by type 1. It is acquired by mucous or cutaneous slight injury or grace. They present different tropism being more frequent the labial or ophthalmic infection by the type 1 and the genital by the type 2, that is acquired almost exclusively by sexual contact. Primary infection is frequently asymptomatic. The human race is the exclusive  reservoir for herpes simplex type 2. Prognosis of herpetic encephalitis is generally lethal, with severe sequelae seen in 70% of survivors. Antiviral treatment decreases mortality and disability to 10%, with minor or moderate sequelae in 50-60%. The aim of these case in to show how and infection may look like a stroke.

CONCLUSIONS

Herpetic encephalitis may be a stroke mimics. Clinical examination, diagnosis and early treatment with intravenous antivirals improves mortality and disability in herpetical infections


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11427 - High rate of acute pancreatitis during the Ramadan fast.
High rate of acute pancreatitis during the Ramadan fast.

Background: During the Ramadan fast Muslims celebrate a month of prayer, dawn-to-dusk fasting and nightly feasts. We aimed to assess whether acute pancreatitis(AP) is more common during the Ramadan fast in people celebrate it.

Methods: The study conducted at the Emergency Department(ED) of Rabin Medical Center, Israel. We compared the occurrence of AP in Muslim population and non-Muslim population during the Ramadan versus the rest of the year.

Results: Over the 10-year study period, 1167 patients admitted to the ED with  AP. Of these, 1069(91.6%) were non-Muslim and 98(8.4%) were Muslim. Of them, 17/98(17.3%) Muslim patients and 95/1069 (8.8%) non-Muslim patients admitted with AP during the Ramadan(RR 1.12, 1.004-1.2, 95%CI, OR 2.15, 1.23-3.8, 95%CI, p=0.01). During the Ramadan, the rate of AP out of referrals was 0.1%(17/15068.) in Muslims vs. 0.004%(95/213913) in non-Muslims(OR 2.54, 1.5-4.25, 95% CI). During the other months of the year, the rate of AP out of referrals was 0.009%(81/86072) in Muslims vs. 0.008%(974/1202405) in non-Muslims(OR 1.16, 0.92-1.45 95%CI, p<0.001).

Conclusions: we found high rate of AP in the Muslim population during the Ramadan. Physicians should be aware of this link and suspect it for Muslim patients presenting with epigastric pain during the Ramadan fast. 


Genady DROZDINSKY, Rona ZUKER-HERMAN, Shachaf SHIBER (Tel aviv, Israel)
08:30 - 17:40 #11750 - High-Dependency Observation Units: which parameters to identify patients at high risk of an adverse prognosis?
High-Dependency Observation Units: which parameters to identify patients at high risk of an adverse prognosis?

Aims: To evaluate independent mortality predictors in a multicentre population of patients admitted in two Emergency Department High Dependency Units (ED-HDU).

Methods: From June, 2014, to July, 2016, we recorded all patients admitted in the ED-HDU,  a clinical setting with a sub-intensive level of care, of University Hospital Careggi and in the ED-HDU in the Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele in a standardized database; after 25 months, we analyzed the database in order to identify predictive parameters of an adverse outcome. To standardize comorbidity, Charlson index was calculated; SOFA score calculation was employed to evaluate organ dysfunction. The primary end-point was ED-HDU mortality.

Results: During the period June 2014-July 2016, 3311 patients were admitted in the two Units, 1822 in Florence and 1489 in Catania, mean age 72±16 years. The most frequent admission diagnosis were COPD exacerbations (9%)and ischemic (11%) heart disease. At HDU admission, 32% of patients presented an infection; respectively 4 and 8%of patients showed a respiratory (pH <7.3 with pCO2 >45 mmHg) or metabolic acidosis (Base excess ≥ -5 or lactate level 1.5 time the reference level); mean SOFA score, calculated on the basis of the worst values in the first 24 hours, was 3.8±3.3. Dispositions after HDU staying were: discharge at home in 827 (25%) subjects and transfer to another hospital ward in 2294 (70%). Overall mortality rate was 5% (n=171): compared with patients with a good prognosis, non-survivors were significantly older (79±12 vs 72±16, p<0.001), presented a higher comorbidity burden (Charlson index 4.0±2.5 vs 2.8±2.5, p<0.001) and a more severe organ dysfunction (SOFA score: 10.0±4.2 vs 3.5±2.9, p<0.001). Number of dysfunctioning systems was significantly higher in patients with a bad prognosis (1.6±0.9 vs 0.6±0.8, p<0.001); renal (73 vs 32%) and respiratory failure (39 vs 17%, all p<0.001) were the most frequent organ insufficiencies among non-survivors. At admission non-survivors presented more frequently an infection (58 vs 32%, p<0.001), with sepsis or septic shock being significantly more frequent among patients with a bad prognosis (respectively 22 vs 11% and 23 vs 4%, all p<0.001), as well as a respiratory or metabolic  acidosis (56 vs 13%, p<0.001). We therefore introduced all the aforementioned parameters (age, Charlson index, SOFA score, presence of infection and acidosis) in a multivariable analysis: an advanced age (RR 1.04, 95%CI 1.02-1.05, p<0.001) and a more marked organ dysfunction evaluated by mean of SOFA score (RR 1.46, 95%CI 1.38-1.54, p<0.001), altogether with presence of acidosis (RR 1.59, 95%CI 1.04-2.42, p=0.031) were independently associated with an untoward prognosis. By ROC curve analysis SOFA score showed an optimal discrimination ability for HDU mortality (AUC 0.9, 95%CI 0.87-0.92, p<0.001).

Conclusions: SOFA score showed an optimal discrimination ability for HDU mortality.


Federico MEO, Arianna GANDINI (Florence, Italy), Paola NOTO, Giuseppe MANGANO, Giuseppe CARPINTERI, Francesca INNOCENTI, Riccardo PINI
08:30 - 17:40 #11815 - High-Voltage Electrical Injury: Epidemiology and prognosis.
High-Voltage Electrical Injury: Epidemiology and prognosis.

Introduction : Electrical injuries are still common cause of accidental burns. They cause devastating complications and long-term socio-economic impact. The purpose of this study is to review one institution's experience with high- voltage electrical injuries.

Patients and methods: A retrospective study was conducted in burn center in Tunis. From December 2012 to January 2014, an analysis of patients who sustained high-voltage electric injuries was carried out. Epidemiological characteristics, extent and severity of burns, the entry and the exit point and the various complications were collected.

Results: During the period of study, 38 patients were included. The mean age was 30 ± 12 years old. There were 36 male and 2 female. The average TBSA was 18 ± 20 with an UBS of 45. Electrical burns are due to work-related accidents in 68.4% of cases and domestic accidents in 23.7%. The most common aetiology was electrical injury (95%). The entry point was the hands in 74%. Associated trauma was documented in one third of cases : an isolated   brain injury in 4 patients, chest trauma in 2 patients and poly-trauma in 5 patients.

Troponin   levels were positive in 21% of cases. Rhabdomyolysis was noted in 86% of cases with a mean CPK level of 12.284 IU /L. 13 patients developed renal failure requiring hemo-diafiltration in 2 cases, and a conventional dialysis in one case.

Complications were : amputations in 10 cases, in-situ thrombosis of the renal artery in one case. 2 patients developed later complications after discharge from hospital : bilateral cataract, and a case of axial hypotonia. Motality occurs in 3 cases among which 2 with renal failure.

Conclusion : High-voltage injuries are essential work-related activities affecting young population. They have far reaching social and economic impact largely. So, education and compliance with safety measures, as well as common sense and respect for the potential danger of electricity, are still essential for avoiding these injuries.

 

 


Dhekra HAMDI, Dhekra HAMDI (tunis, Tunisia), Ahmed SOUAYAH, Najah HAJJAM, Wafa AZAZA, Hamdi DOGHRI, Amel MOKLINE, Amanallah MESSADI
08:30 - 17:40 #11078 - Hip pain. Should we look further?
Hip pain. Should we look further?

CASE REPORT: a 67-year-old woman with a history of cholecystectomy and type 2 diabetes mellitus, and infiltrating left breast cancer treated with chemotherapy and surgery 8 years ago visits our emergency room for persistent pain in the left hip and inguinal region. The patient denies trauma or data of concomitant infection and has been treated with anti-inflammatory drugs for 2 months without experiencing improvement and in this time she has consulted in our Service up to 4 times performing physical examination and radiological studies of the hip and pelvis showing no abnormalities (Figure 1). In her current visit the patient is affected because of the left inguinal pain. No hernias or masses are palpable and the passive mobilization of the left hip is very painful especially with the maneuvers of external rotation. At this point, a lumbosacral Computed Tomography (CT) is required, in which a heterogeneous destruction of the left sacrum  (Figure 2) is evidenced by a large mass that crosses the sacroiliac joint, affecting the left iliac bone and the L5 vertebra (Figures 3 and 4). The patient is admitted to an Internal Medicine ward.

DIFFERENTIAL DIAGNOSIS: pain due to degenerative bone disease (osteoarthritis), avascular hip necrosis, infectious disease (spondylodiscitis, abscess ...), pain referred by psoas pathology (hematoma, abscess ...), referred pain from abdominal (inflammatory, infectious or tumoral) pathology, pain caused by a neoplasm.

EVOLUTION: bone scans are performed, showing intense uptake in the left and left iliac sacs, femoral neck on the same side, and T6 and T12 vertebrae (Figure 5) and PET/CT showing hypermetabolic lesions in the same anatomical regions. The thoracoabdominal CT does not show pathology at other levels. Tumor markers are negative and CT guided mass puncture is performed, determining the anatomopathological study of metastasis of breast carcinoma.

FINAL DIAGNOSIS: bone destruction due to late metastasis of breast neoplasm 

DISCUSSION: pain is one of the most frequent reasons for consultation in the Emergency Department (ED), with musculoskeletal origin being one of the most prevalent and in most cases it is the manifestation of benign diseases. Pain at the level of the axial skeleton and/or limbs is usually due to traumatic or degenerative pathology. Most of the time, and even more so in the absence of trauma, the physical examination and the basic complementary tests are anodyne, so a therapeutic trial is usually used, waiting for an adequate response. However, there are data that should be an alert and make us think about the need for more advanced explorations. It would be interesting to identify which clinical data are most likely to guide a serious pathology behind a common symptom and overcome the reluctance that still exists to request specific tests with high diagnostic yield.

 


Daniel SÁENZ ABAD (ZARAGOZA, Spain), María Del Carmen LAHOZA PÉREZ, Jordi PONS DOLSET, Marta JORDÁN DOMINGO, Ana ILUNDAIN GONZÁLEZ, Sofía LUNA GARCÍA
08:30 - 17:40 #11517 - Histamine Fish Poisoning (HFP) and allergy: a significant difference.
Histamine Fish Poisoning (HFP) and allergy: a significant difference.

The allergic reactions are an important part of access to Emergency Departments. Often they are phenomena of mild to medium intensity, but frequently severe reactions up to anaphylactic shock are observed.
In our ED, in addition to supportive care, we determine tryptase serum levels which is an interesting marker in subjects at risk of anaphylaxis. In this survey, we analyze the role of tryptase in order to differentiate real allergic syndrome from other syndromes causing similar effects with a different mechanism, avoiding diagnostic errors that might cause therapeutic difficulties, as in the case of Scombroid syndrome (Histamine Fish Poisoning – HFP),  a complex of symptoms caused by biogenic amines, mainly the histamine, contained in fishfood. 

In this work, We observed 50 patients with allergic reaction and 10 with HFP trying to correlate serum levels of tryptase with the severity of the clinical presentation, and medical history, noting that in case of certainly determined allergic reaction (insect stings, drugs, etc.), tryptase levels increased to varying degrees, while in cases of HFP (symptoms onset within minutes to hours after fish ingestion, developing a severe histamine-mediated reaction, without a history of previous allergic reactions), tryptase levels was unchanged. Recognizing the HFP can be extremely difficult, especially in ED, but, although the basic treatment is basically the same as the allergic reactions, however in HFP may be useful other drugs and even gastric lavage to resolve symptoms. In addition, according to Italian legislation, HFP must be notified to authority. We also tried to define a scheme of recommended treatment according to different physiopathological mechanisms of the two syndromes, suggesting a long term follow up in case case of HFP, considering that this illness is not a simple poisoning from histamine. Notwithstanding it is linked to high levels of this substance in fishes of certain species contaminated by bacteria, the pathogenesis of HFP is still not clearly delineated.


Giorgio RICCI, Massimo ZANNONI (VERONA, Italy), Gianni TURCATO, Lucia ANTOLINI, Chiara BOVO, Mariano BELLONI
08:30 - 17:40 #11595 - HIV Testing Within the Emergency Department for Patients with Bacterial Pneumonia: An Audit.
HIV Testing Within the Emergency Department for Patients with Bacterial Pneumonia: An Audit.

Background

In 2006, BHIVA national audit showed that 24% of deaths from HIV were directly due to late diagnosis. Late diagnosis continues to occur, contributing to resistance patterns, morbidity and mortality. Pneumonia is a common ED diagnosis with a mortality rate up to 14%. Patients with HIV more commonly develop pneumonia.

Aim

To identify if HIV is being tested for within the ED for patients diagnosed with bacterial pneumonia.

Standards

The following standards were set using BHIVA, UK National guidance for HIV Testing 2008, NICE (December 2014). CG191: Pneumonia in adults and BTS (2009) Guideline for the Management of CAP in Adults:

  1. All patients with the clinically indicated illness, bacterial pneumonia should be tested for HIV.
  2. Moderate and severe pneumonia (CURB-65 score >/=2) should have bacterial pneumonia confirmed in the form of blood culture, sputum sample, Urinary Legionella and Pneumococcal tests.

Sample

This audit was undertaken in a large University Teaching Hospital’s ED, which sees 130,000 patients per year, of which 1.54% receive a diagnosis of pneumonia. A random sample of 496 patients diagnosed with pneumonia, during January-November 2016 was obtained. 4 patients were excluded due to lack of notes or patient mortality, leaving 492 patients remaining. The sample was predominantly white British (93.9%), with a mean age of 74.5 years (Interquartile range 68-85 years), and a female predominance (n=256, 52%).

Methodology

Data was collected retrospectively by reviewing scanned patient notes and laboratory results. A data collection tool was used, which required information on whether a HIV test, CXR, Blood culture, Sputum sample, Urinary Legionella and Pneumococcal Antigen had been performed. The data collection team received training and written guidance on how to obtain the required information. The data was quantified, and information on how many patents received HIV tests and microbiological tests confirmed.

Results

Of the 492 patients, a diagnosis of pneumonia was made using CXR in 80% (n=392). 222 patients (54.9%) received microbiological testing in the form of blood cultures (n=201, 40.9%), sputum samples in (n=43, 8.7%), Urinary Legionella (n=19, 3.9%) and Pneumococcal antigen (n=18, 3.7%). Of these, 45 (9.2%) had confirmed bacterial pneumonia, with 2 (4.4%) receiving a HIV test. However, 222 (45.1%) had no microbiology samples taken at all, and of these only 4 had HIV tests performed. In total therefore, 6 (1.2%) HIV tests were performed from the 492 patient sample, all of which were negative.

Conclusion

In the ED pneumonia is commonly diagnosed by CXR alone. Microbiology was performed in 54% of patients but only 9.2% of cases of bacterial pneumonia were confirmed. HIV taking is seldom performed, therefore large numbers of patients with pneumonia remain untested.

Recommendations

To provide education and a written reminder to perform HIV and microbiological tests for patients with suspected bacterial pneumonia in the form of a checklist.


Sophie BURNAGE (Stoke-On-Trent, United Kingdom), Ruth KINSTON, Mirella FRY, Alexander GORRIE, Bethan HARRIS, Natalie PEREZ LEACH, Elin ROWLANDS
08:30 - 17:40 #11564 - HIV Testing Within the Emergency Department for Patients with Bacterial Pneumonia: An Audit.
HIV Testing Within the Emergency Department for Patients with Bacterial Pneumonia: An Audit.

Background

In 2006, BHIVA national audit showed that 24% of deaths from HIV were directly due to late diagnosis. Late diagnosis continues to occur, contributing to resistance patterns, morbidity and mortality. Pneumonia is a common ED diagnosis with a mortality rate up to 14%. Patients with HIV more commonly develop pneumonia.

Aim

To identify if HIV is being tested for within the ED for patients diagnosed with bacterial pneumonia.

Standards

The following standards were set using BHIVA, UK National guidance for HIV Testing 2008, NICE (December 2014). CG191: Pneumonia in adults and BTS (2009) Guideline for the Management of CAP in Adults:

  1. All patients with the clinically indicated illness, bacterial pneumonia should be tested for HIV.
  2. Moderate and severe pneumonia (CURB-65 score >/=2) should have bacterial pneumonia confirmed in the form of blood culture, sputum sample, Urinary Legionella and Pneumococcal tests.

Sample

This audit was undertaken in a large University Teaching Hospital’s ED, which sees 130,000 patients per year, of which 1.54% receive a diagnosis of pneumonia. A random sample of 496 patients diagnosed with pneumonia, during January-November 2016 was obtained. 4 patients were excluded due to lack of notes or patient mortality, leaving 492 patients remaining. The sample was predominantly white British (93.9%), with a mean age of 74.5 years (Interquartile range 68-85 years), and a female predominance (n=256, 52%).

Methodology

Data was collected retrospectively by reviewing scanned patient notes and laboratory results. A data collection tool was used, which required information on whether a HIV test, CXR, Blood culture, Sputum sample, Urinary Legionella and Pneumococcal Antigen had been performed. The data collection team received training and written guidance on how to obtain the required information. The data was quantified, and information on how many patents received HIV tests and microbiological tests confirmed.

Results

Of the 492 patients, a diagnosis of pneumonia was made using CXR in 80% (n=392). 222 patients (54.9%) received microbiological testing in the form of blood cultures (n=201, 40.9%), sputum samples in (n=43, 8.7%), Urinary Legionella (n=19, 3.9%) and Pneumococcal antigen (n=18, 3.7%). Of these, 45 (9.2%) had confirmed bacterial pneumonia, with 2 (4.4%) receiving a HIV test. However, 222 (45.1%) had no microbiology samples taken at all, and of these only 4 had HIV tests performed. In total therefore, 6 (1.2%) HIV tests were performed from the 492 patient sample, all of which were negative.

Conclusion

In the ED pneumonia is commonly diagnosed by CXR alone. Microbiology was performed in 54% of patients but only 9.2% of cases of bacterial pneumonia were confirmed. HIV taking is seldom performed, therefore large numbers of patients with pneumonia remain untested.

Recommendations

To provide education and a written reminder to perform HIV and microbiological tests for patients with suspected bacterial pneumonia in the form of a checklist.


Sophie BURNAGE (Stoke-On-Trent, United Kingdom), Ruth KINSTON, Alexander GORRIE, Bethan HARRIS, Elin ROWLANDS, Natalie PEREZ LEACH, Mirella FRY
08:30 - 17:40 #11288 - Holospinal Epidural Abscess due to Streptococcus Milleri Group: a case report and literature review.
Holospinal Epidural Abscess due to Streptococcus Milleri Group: a case report and literature review.

INTRODUCTION

 Holospinal epidural abscess (HEA) is a rare infection in which abscess extends from the cervical spine to the sacrum. We report a case of HEA from C2 to sacrum by Streptococcus Milleri Group (SMG) and review the previous reports of HEA.

 

CASE REPORT

 A 42-year-old man, without diabetes mellitus and untreated dental caries, presented to the local hospital with two-week history of fever, back pain, and progressive tetraparesis. His manual muscle test (MMT) revealed 0-3/5 in the upper limbs and 0/5 in the lower limbs. There were sensory disturbances below the C5 level and atonic anal sphincter. Magnetic resonance imaging (MRI) of the cervical spine showed a space occupied lesion from C2 to thoracic spine. On the same day, he was referred to our hospital for diagnosis and treatment including an operation. Further MRI scans of the whole spine showed  epidural fluid collection from C2 to S1. Plain computed tomography showed abscesses in the left psoas muscle and the right piriformis muscle. Vegetation was not detected by the transthoracic echocardiography. Then, he underwent emergency laminoplasty at C3-7, laminectomy at Th12-L4, epidural drainage, and placed on broad-spectrum antibiotics (MEPM and LZD). Four days after surgery, SMG (S.intermedius) grew in blood and pus. Therefore, antibiotics were changed to ABPC. Three months later, his MMT recovered to 4/5 in  all limbs, and he was transferred to a rehabilitation facility.

 

DISCUSSION

 According to  previous studies in the literature, SMG occupied only 0.56% of pathogens in the  cases of spinal epidural abscess. In contrast, SMG was detected as a pathogen in 4 of 15 reports of HEA, including the current case. Furthermore, another abscess was identified in 2 of 4 SMG cases. In cases of HEA, SMG should be a suspected pathogen and a whole-body CT scan might be necessary to survey the second abscess.


Keisuke MAEDA (Hyogo-ken, Japan), Shota KIKUTA, Satoshi ISHIHARA, Shinichi NAKAYAMA, Keisuke KINTAKA, Shuhei OZAKI
08:30 - 17:40 #11712 - Homozygous sickle cell anemia discovered in older adult at the emergency department.
Homozygous sickle cell anemia discovered in older adult at the emergency department.

Introduction:

Sickle cell disease (SCD) is an inherited hemoglobin disorder, caused by the presence of hemoglobin S. The syndrome comprises different genotypes that include homozygous S (HbSS), compound heterozygous forms of HbS/C and β-thalassemia (HbSβ0 thalassemia and HbSβ+ thalassemia). In patients of African ancestry, HbSS is the most common genotype (65–70%). Homozygous forms are generally discovered in childhood because of the frequency of painful episodes, ongoing hemolytic anemia and progressive multi-organ damage.

We report here the case of a 50 years old woman who was admitted in the emergency department for chest pain and who was discovered with SCD during her hospitalization.

Case report:

A 50 years old woman was referred to our emergency department for management of pulmonary edema. Her relevant medical history included a cholecystectomy 30 years ago, left leg amputation 2 years ago and anemia.

The patient was algic, dyspneic and febrile (38.50). Heart rate was 120 beats per minute; blood pressure was 80/45 mm Hg; SpO2: 75% in room air; respiratory rate: 30 cycles per minute. Chest x ray showed radiographic abnormalities consistent with pulmonary edema. Additional exams revealed Hb: 8.9 g/dL, HTC: 23%, MCV=89 fl, Reticulocytes=220.000 el/mm3, Na: 134 mmol/L, K+: 4.9mmol/L, Cl−: 110.Transthoracic echocardiography showed a normal mean ejection fraction (62%), severe pulmonary hypertension (75 mmHg), tricuspid regurgitation, right ventricular dilation and paradoxal septum. Pulmonary embolism was diagnosed by an angiothoracic scan so the patient benefited from heparin therapy and needed hemodynamic support for cardiogenic shock.

A blood smear was done which showed many sickle cells. Hemoglobin electrophoresis showed presence of 80.6% of HbS and 16.4% of fetal Hemoglobin (HbF). The solubility test was positive. Our patient died from hyperhemolysis crisis before discovering the diagnosis of SCD.

conclusion:

SCD usually manifests early in childhood. In our case the presence of HbF may explain the mild form of the SCD and the delay of the diagnosis. The patient’s medical history and the clinical condition are likely to be explained by complications of SCD.


Mohamed Amine KALLEL (tunis, Tunisia), Dhouha BAHRI, Aya CHAKROUN, Zaouche KHEDIJA, Mohammed Chekib BOUALI, Neila BEN ROMDHANE, Majed KAMEL
08:30 - 17:40 #11322 - Hospital Disaster Risk Assessment in the hospitals of province East Azerbaijan.
Hospital Disaster Risk Assessment in the hospitals of province East Azerbaijan.

Introduction: Hospitals considered as the most important of health care centers to deal with natural and unnatural disasters. Structural, non-structural, and functional components of hospitals must be prepared when hazards or disasters occur. The aim of the present study was to determine the level of hospital safety for encountering with disaster.

Materials and Methods: This cross-sectional descriptive study was conducted on a total of 40 hospitals enrolled into the study through census method. The hospitals was assessed by provincial disaster experts and two technical engineers affiliated to Tabriz University of Medical Sciences using a checklist of hospital disaster risk assessment provided by the World Health Organization (WHO), including 5 sections and 145 indices for the safety assessment of hospitals. The minimum acceptable score was 60. The level of safety were classified in three groups included 60-70: class of 6, 70-80: class of 7, 80-90: class of 9 and 90 > class of 10. The data were analyzed using SPSS V.17 software.

Results: Of the 40 hospitals, 21 hospitals in the functional section and 17 hospitals in the structural and non-structural sections could obtain the minimum acceptable score. In the functional section, at least 15.73 % and maximum 92.02% of items were observed. The minimum and maximum percentages of cases observed in the structural section were 12.88% and 88.66% and in the non-structural section were 8.33% and 97.5%.

 Conclusion: According to the results, less than half of the hospitals have a minimum level of safety. Considering the history of disasters in this Province, training of personnel to enhance safety performance was suggested. It seems that reconstruction and making safety of hospitals buildings could increase the structural safety factor. Furthermore, it might be effective to improve electronically systems and telecommunications systems for non structure safety factor. 

Key words: disasters, risk assessment, hospital, Tabriz

 


Samira ASAEDI, Elanz ASGHARI, Farnaz RAHMANI (Tabriz, Islamic Republic of Iran), Rajaie Ghafouri ROZBEH
08:30 - 17:40 #10250 - How disabled patients evaluate their care in the Emergency Department ?
How disabled patients evaluate their care in the Emergency Department ?

Introduction: the care of a disabled patient was identified as a priority at the French national disability conference in 2016. Is the use of ED  for disabled patients frequent ? Is it detrimental to these fragile patients? Can we improve the flow process?

Materials and methods: A on-line retrospective multicentric questionnaire was sent via a web platform to representatives of disabled associations from November 2015 to September 2016. 5 series of questionnaires over 2 consecutive months: identification of the needs and expectations of patients and families, satisfaction questionnaire consisting of 15 questions on the care of patients in their care path and in particular in emergency departments.

Results: 2554 responses to the questionnaires were analyzed. Patients with disabilities use the hospital (34%) for routine (11.6%) common (19%) dental (12.5%) disability-related care (16.08%). The satisfaction index for hospital care tends to deteriorate in emergencies (+ 18% of unmet patients and -7% very satisfied) or in medical or surgical departments (7% of unmet need and -4% very satisfied). The indices of non-satisfaction relate to the lack of information of accompanying persons 34% (-7%). The accompanying person at the choice of the handicapped patient is respected (75%).

Discussion: The overall assessment of the management of patients with disabilities requires improvement in ED. Taking into account the information given by the accompanying persons is generally integrated by ED personnels, but seems still perfectible, especially when carrying out the care. Based on the results of the patient questionnaires, we have implemented to our emergency personnel a questionnaire to evaluate our practices in order to know the specific difficulties encountered by caregivers when taking care of a disabled patient. In parallel with the drafting of a charter on the care path, we have set up a working group to regularly improve practices, in particular on communication tools and the creation of a specific pathway for care of disabled patient in the emergency room.

Conclusion: The management of patients with disabilities in emergencies requires improvement, depending on the patients and their representatives. Several perspectives of improvement are set up in the emergency department.


Eric REVUE (Paris), Lucille DUMOULIN, Gaelle LAVIE-SALOMON, Alexandre HENNIART, Amine ABDALLAH, Emilie RIVIERE, Pascal JACOB, Monique TITTON
08:30 - 17:40 #11358 - How does urban versus rural areas influence the prognosis of cardiopulmonary arrest.
How does urban versus rural areas influence the prognosis of cardiopulmonary arrest.

Introduction: cardiopulmonary arrest is one of the most fearst complication of a wide variety of pathologies. While it is important to diagnose the cause of the cardopulmonay arest, high quality CPR(cardiopulmonary ressctation)  and correctly managing the case has been shown to improve survival outcomes after cardiac arrest. The aim of the study is to relieve the cardiopulmonary arrests evolution after cardiac resuscitation and also how are they influenced depending on  several criteria: sex, age, arriving time and if cardiac resuscitation was started by bystanders or by another First Aid crew.

Material and Methods:

We used retrospective medical study based on the statistical data applied on SMURD Sibiu’s database. We analyzed 221 cases with cardiac arrest dispatched to SMURD-TIM Sibiu (Mobile Emergency Service for Resuscitation and Extraction - Mobile Intensive Care Unit) during the period between 01.01.2016-28.02.2017. For processing the database and obtaining the final data Microsoft Excel has been used.

Results and Discussions:

From statistical report it is shown that 221 cases of cardiopulmonary arrest were dispatched to SMURD-TIM Sibiu which represents around 20 procent of the total number of cases. We wanted to examin survival rate and pacient outcome and out of 221 cardiopulmonary arrest we had the survival rate of 18.1%. We divided pacients by: sex and had 66.06% male pacients and 33.94% famele pacients, by age in five categories: catagory 1 (age 1-30years) representing 2.71 procent, category 2 (age 31-45 years) representing 7.69%, category 3 (age 46-65years) representing 34.39%, category 4 (age 66-80years) representing 33.94 procent and category 5 (age above 80 years) representing 18.55%. We had 61.99% of pacients livinng in an urban areas and 38.01% pacients living in a rural areas. Depending on the arrival time we divided cases into 5 categories: the first category (1-5 minutes) representing 47.06%, second category (5-10 minutes) representing 14.03%, the third category (10-15 minutes) representing 6.79%, the fourth category (15-20 minutes) representing 10.41% and the fifth category (more than 20 minutes) representing 19.91%. The rate  In 59 cases representing 26.71%, we had a First Aid crew arriving first at the pacient and in 7 cases representing 3.71% recived bystander CPR. 

Conclusions: although cardiopulmonary arrest has a bad prognosis, the sortest response time had the biggest survival rate (57.5%). Even if a first aid crew arrives in a short time, for the best pacient outcome it is important that the ACLS is provided as quickly as possible by a doctor a specialized medical crew, while the succes rate after cardiopulmonary arrest in pacients living in urban areas was 76.61%, versus 24.39% which was the succes rate for pacients living in rural areas. Bystander CPR was performed in 7 cases representing 3.17% with survival rate of 71.43% compared to the 18.1% which represents the average rate of survival after cardiopulmonary arrest.


Gabriel BOBES, Gabriel BOBES (Sibiu, Romania), Diana MD LOLOIU, Ana-Daniela MD TARAN, Anamaria TELEBUS, Francesca Iulia PAIUS, Dumitru PAMFILOIU, Alexandru Daniel NICULA, Alexander WANDSCHNEIDER
08:30 - 17:40 #10930 - How to become european stroke center? - organizational activities in Emergency Department and the Department of Neurology in Lublin Medical University Hospital No. 4.
How to become european stroke center? - organizational activities in Emergency Department and the Department of Neurology in Lublin Medical University Hospital No. 4.

   Stroke is the third leading cause of death and the first cause of disability in people over 40 years old. In 2014 in Poland, only 7% of patients were treated in a causal manner with intravenous thrombolysis. Few centres in Poland also apply endovascular treatment of ischemic stroke (thrombectomy). The use of such methods of treatment significantly increases the chance of regaining full fitness and leaving only a small neurologicall deficit.

   In Lublin Medical University Hospital No. 4, till 2014 less than 5% of stroke patients were treated with intravenous thrombolysis, ie. % much lower than the national average, and thrombectomy had not yet been performed. This relatively poor result prompted us to analyze the causes and "bottlenecks" to improve this state of affairs. At the end of 2015 we made a number of organizational changes both in the Emergency Department and the Department of Neurology. As the result of these actions in 2016, up 22,8% of all stroke patients received effective thrombolytic therapy, and also thrombectomy was performed in 39 patients.

   The aim of the study is to present organizational activities that contibuted to the spectacular improvement in the treatment of patients with stroke. Such a high percentage of patients treated in causal way (almost 3 times more than the average in Poland) is due to the coordinated actions of both well trained ED staff, radiologist and the stroke team of the Department of Neurology. The introduction of special procedures for dealing with patients with stroke, which is in force since September 2015 resulted in shortening the time of arrival the patient to the stoke unit in the Neurology Department to take the treatment (ie. Door-to-needle time) to an average 30 minutes, which situates our center among the best stroke centers in Europe. 


Marcin WIECZORSKI (LUBLIN, Poland), Piotr LUCHOWSKI, Konrad REJDAK
08:30 - 17:40 #11382 - Hydatid cyst rupture with anaphylactic shock.
Hydatid cyst rupture with anaphylactic shock.

Background : Hydatid disease is a parasitic infestation by a tapeworm of the genus echinococcus. While typically asymptomatic,  the most common complication is rupture of the cyst which can lead to secondary infection,  jaundice and anaphylaxis.
Introduction : a 26 year old, postnatal patient was brought to the emergency department having become acutely unwell after performing abdominal exercises at home.  The patient had no known illnesses or allergies and yet presented with altered mental status and shock of unknown etiology. 
Clinical significance: as the patient presented with atypical anaphylactic shock,  with no clear alergen exposure,  it was necessary to rule out other etiologies of shock (cardiogenic,  hypovolemic,  septic). This was accomplished through the early use of ultrasound and eventually confirmed with a CT scan. 
Management : this case demonstrated the need for early management of shock from a pathophysiological standpoint until the diagnosis was established after which the patient's treatment included an etiological approach for an eventual successful outcome.  

Monica PUTICIU, Aconi ANA, Robert Cristian KATAI, Olga MITREANU, Johanna Elizabeth KATAI (Arad, Romania)
08:30 - 17:40 #10488 - Hygiene compliance among emergency medical service personnel – A multicenter observational study on quality and challenges.
Hygiene compliance among emergency medical service personnel – A multicenter observational study on quality and challenges.

Background

Healthcare associated infections caused by environmental microbial contamination and poor hygiene are straining on society with increased morbidity, mortality and economic burden. Emergency medical service (EMS) personnel often encounter various patients and settings during a shift, thus posing a source of microbial transmission towards the patients. However, despite the fact that hand hygiene (HH) compliance, is the single most effective way to prevent transfer of microbes, it has rarely been studied in an EMS setting. By documenting and assessing HH compliance and adherence to guidelines among EMS personnel, we seek to achieve a profound knowledge of HH status and challenges related.

Method

A semi-blinded, multi-centre observational study, including frontline ambulances from city areas with approximately 60.000 to 187.000 frontline courses annually, in four EMS settings (Finland, Sweden, Australia and Denmark) is ongoing. Primary outcome is HH and secondary outcomes are hair, nails, jewellery, and national/local guidelines. The observers register use of hand rub, hand wash and gloves on following five conventional occasions: before touching a patient, before clean/aseptic procedure, after body fluid exposure risk, after touching a patient and after touching patient surroundings. Descriptive analyses of primary and secondary outcomes are assessed in total, and compared by country, using the Chi2/Fisher’s exact test.  

Perspective

We expect to gain a profound knowledge of EMS HH status and challenges related, thus we are able to plan future educational interventions and training, adjust supply of HH equipment and design implementable guidelines.  Results will be ready in August 2017.


Heidi Storm VIKKE (Kolding, Denmark), Svend VITTINGHUS, Matthias GIEBNER, Hans Jørn KOLMOS, Karen SMITH, Maaret CASTRÉN, Veronica LINDSTRÖM
08:30 - 17:40 #10932 - Hyperbaric Oxygen Therapy on Diabetic Foot: Review.
Hyperbaric Oxygen Therapy on Diabetic Foot: Review.

Currently, Diabetes Mellitus (DM) is one of the most important public health problems worldwide because it is a disease with a high morbidity and mortality rate. Diabetic foot ulcers (DFU) are associated with significant impairment of quality of life, increased morbidity and mortality and are a huge drain on health care resources.  DFUs develop as a consequence of a combination of factors, most commonly peripheral neuropathy (loss of the sensibility of pain), peripheral vascular disease and some form of unperceived trauma. All patients with diabetes should have an annual screen to identify their foot ulcer risk status. Multiple adjuvant therapies have been proposed to accelerate wound healing in patients with diabetes and foot ulcers. Hyperbaric oxygen therapy (HBOT) is the application of 100% oxygen at two or three times the atmospheric pressure at sea level. This pressure increases arterial and tissue oxygen tension (2000 mmHg and 400 mmHg, respectively), which causes most of the physiological and therapeutic effects of this treatment. This therapeutic procedure has a range of positive effects for the healing process. The value of HBOT in the treatment of diabetic ulcers is still under debate. Available evidence suggests that HBOT may improve the healing of diabetic ulcers, but it comes from small trials with heterogeneous populations and interventions. Therefore, the objective of this study is to identify evidence available in the literature related to the treatment of diabetic foot with hyperbaric oxygen therapy in order to evaluate its efficacy.


Rosemary DANIEL, Deborah FERREIRA, Matheus FERREIRA, Santos LUIS, Tufik GELEILETE, Lelio PINTO, Melissa CESARIO (ribeirão preto, Brazil), Jussara AQUINO, Omar FERES
08:30 - 17:40 #11257 - Hypokalemia presenting in a patient with Crush syndrome.
Hypokalemia presenting in a patient with Crush syndrome.

Introduction: Crush injury leads to Crush syndrome, which is a reperfusion injury, a result of traumatic rhabdomyolysis. Release of muscle cells’ contents leads to acute kidney injury. Potassium is one of the main body ions, situated mostly intracellular. Usually with Crush syndrome we see hyperkalemia, which causes dysrhythmias. Against all odds, we review a case where Crush syndrome presented with hypokalemia – differently than algorithms claim. Hypokalemia is generally defined as a serum potassium concentration that is lower than 3.5 mmol/L and it is prevalent in 20% of hospitalised patients. It makes hypokalemia a formidable diagnostic challenge, especially in situations where its’ presentation is atypical.

The aims of this review are to analyse the pathophysiology of electrolyte imbalance with Crush syndrome, possible complications of Crush syndrome and sepsis, relationship between Crush syndrome, hypokalemia and sepsis.

Case report: A 64 year-old man with a history of epilepsy brought to the emergency department by EMT from local hospital ER with suspicion of intracerebral hematoma.  The patient was somnolent, no complaints or further medical history was present. According to EMT, the man fell 3 days ago and since the accident he spent time in bed, however his condition kept worsening. Yesterday the patient stopped eating and his consciousness altered. On admission the patient was cachectic,  Glasgow Coma Scale was 10, blood pressure of 131/73mmHg, bradycardic with 33beats/min, diuresis was concentrated.  Physical examination revealed a fluctuating, soft formation in sacral area.

  ECG showed AV rhythm, broad QRS, bradycardia. Complete blood count showed lymphocytopenia (0,2*10e9/L), low platelet count (112*10e9/L). Laboratory tests revealed urea concentration of 37,8 mmol/l, creatinine 250mkmol/l; sodium concentration of 172mmol/L, potasium – 3,2mmol/L, magnesium- 1,51 mmol/l;  D -dimer 825 mkg/L, myoglobin – 6093,1 mkg/L, CRP- 347,1, mg/l . Noncontrast head computerized tomographyA was performed and showed no evidence of intracerebral hematoma.

 Nephrologist consulted the patient due to acute renal failure, he advised to continue with fluid therapy as there was no indication for urgent dialysis. Cardiologist advised on temporary electrocardiostimulation. The patient was hospitalised in ICU with diagnoses of sepsis, Crush syndrome and multiorgan failure. In ICU patient stopped breathing and the monitor showed asystole. Arterial blood potassium was 2,3 mmol/L, the infusion therapy with KCl was continued. Blood culture came back negative. Despite that the patient was ventilated and resuscitated according to the protocol, asystole was present until the patient was pronounced dead.

We conclude: if Crush syndrome occurs, when patient history is absent, it is appropriate to expect different presentation than usual, act as aggressive as possible, adjust expectations and indications for dialysis and fluid therapy.



Ruseckaitė RENATA, Trumpickaitė MIGLĖ (Vilnius, Lithuania)
08:30 - 17:40 #11278 - Hypokalemia: Is cause of cardiac arrest?
Hypokalemia: Is cause of cardiac arrest?

INTRODUCTION: Hypokalemia is generally defined as a serum potassium level of less than 3.5 mEq/L (3.5 mmol/L). Severe hypokalemia is a level of less than 2.5 mEq/L. Hypokalemia is a potentially life-threatening imbalance that may be iatrogenically induced. In this study we present to a case with cardiac arrest because of hypokalemia.
CASE: 29 –old –year female patient was admittted to the ED because of cardiac arrrest by 112 Emergency Service. In history she admitted to ICU as a result of general state disorder and dialysis ( caused creatinin=10) in another hospital 2 months ago. She was using Methyl prednisolone with prediagnosed vasculitis since that time and had complaints of palpitaion and weakness 2 days.112 EMS performed Cardiapulmonary Resuscitation because of Cardiac Pulmonary Arrest at home. In first laboratory results revealed severe asidosis (pH:6,99) and hypokalemia (K:1,2 mEq/L) in ED. When we deepen history, she had taken Lactuloz (Duphalac) 670 mg because of constipation. Arterial Blood Gase values: pH: 7,02; 6,99; 7,06 HCO3:6,6;14,2;13,6 K:1,3;1,2;1,5 respectively. After NaHCO3, KCl infusion and hidration for initial treatment she was interned to ICU.
CONCLUSION: The symptoms of hypokalemia are nonspecific and predominantly are related to muscular or cardiac function. Abnormal findings may reflect the underlying disorder. Severe hypokalemia may manifest as bradycardia with cardiovascular collapse. In some cases hypokalemia may lead to cardiac arrest as in this case.


Mehmet UNALDI (Istanbul, Turkey), Soner ISIK, Didem AY, Ersen GUNDUZ, Ahmet DEMIR, Vehbi OZAYDIN, Onur INCEALTIN, Kurtulus AÇIKSARI, Hatice ERYIGIT
08:30 - 17:40 #9800 - Hypotension, metabolic acidosis, hypoxemia: Determinants of hospital mortality of patients with aluminum phosphide poisoning.
Hypotension, metabolic acidosis, hypoxemia: Determinants of hospital mortality of patients with aluminum phosphide poisoning.

Background: Rice Tablet, with the scientific chemical name of aluminum phosphide (ALP), is the most common pesticides and insecticides in agriculture and horticulture and is used to protect beans, cereals, and rice. Poisoning with this tablet is associated with a high mortality rate. The aim of this study was to evaluate patients who committed suicide with rice tablets and referred to Sina Hospital, Tabriz during the years 2011-2015.
Materials and Methods: In a retrospective study that was conducted at Sina Hospital affiliated to Tabriz University of Medical Sciences, medical records of patients with suicide attempt with rice tablets during the years 2011-2015 were evaluated. During the mentioned period, 90 patients with rice tablet poisoning were admitted to the hospital. The required information was recorded in the check list.

Results: Out of 90 patients, 72 patients (80%) had ALP tablets poisoning. The mean age of subjects was 27.52 ± 0.13 years. The average hospital length of stay was 3.42 ± 2.71 days. In these patients mean arterial pressure (MAP) above 71.5 mmHg with 97% sensitivity and 56% specificity, serum pH above 7.26 with 81% sensitivity and specificity 61%, serum bicarbonate above 14.85 mmol / L with 90% sensitivity and 54% specificity, arterial oxygen saturation above of 92% with sensitivity of 93% and specificity of 54% were calculated for the survival prediction until hospital discharge. All variables are related to admission time in the emergency department.

Conclusion: The results of the current study show that the survival of patients with ALP poisoning is related with MAP, pH and serum HCo3, arterial blood oxygen saturation at the time of admission in the emergency department. Next prospective studies are recommended for more accurate evaluation of the effect of these variables on the patients' survival.


Farzad RAHMANI (Tabriz, Islamic Republic of Iran), Parisa KHODAGHOLIZADEH, Haniyeh EBRAHIMI BAKHTAVAR, Farnaz RAHMANI, Pegah SEPEHRI MAJD
08:30 - 17:40 #11209 - Hypothermia-associated coagulopathy as part of the lethal triade in alpine multiple trauma patients - a combined epidemiological and experimental prospective in vitro study.
Hypothermia-associated coagulopathy as part of the lethal triade in alpine multiple trauma patients - a combined epidemiological and experimental prospective in vitro study.

Introduction: Multiple trauma patients in alpine and remote areas are prone to accidental hypothermia due to the low ambient temperature and long rescue times. Hypothermia with acidosis and coagulopathy is part of the lethal triad in trauma and accounts for the high mortality in multiple trauma patients. The detrimental effects of hypothermia on coagulation are exerted by inhibition of the mobility and aggregation of platelets. Hypothermia also inhibits plasma factors and thereby decreases clot formation and clot firmness. These effects result in increased blood loss, aggravation of shock, and hypoperfusion of vital organs. The aim of this combined clinical and experimental study was to identify the impact of hypothermia on the various components of the coagulation system and to illustrate its effect on patients sustaining multiple trauma in alpine and remote areas of the European Alps.

Methods: The International Alpine Trauma Registry (IATR) is a prospective multicentre study collecting data from multiple trauma patients rescued from mountain and remote areas. Data analysis included multinomial logistic regression and One-way ANOVA. Secondly, we performed an in-vitro analysis of blood samples from 18 healthy volunteers, cooled to five different temperatures relevant in hypothermia-associated hypothermia, at each stage ROTEM- and Multiplate-Analysis was performed.

Results: Out of 104 patients (15.4% female and 84.6% male), core temperature was mean 31.0°C ±5.3°C, 32 patients (58.2%) were hypothermic (≤35.0°C). Out of the population with severely impaired coagulation (INR > 1.3) more patients were hypo- than normothermic (82.4% vs 17.6% p=0.025). Hypothermic patients had more frequently low systolic blood pressure (≤90mmHG) (p=0.001). The preliminary data of the in vitro analysis revealed a prolonged clotting time (CT) in ExTEM (CT37.0°C 67.3±2.8sec; CT13.7°C 134.1±8.8sec) as well as a reduction of the maximum clot firmness (MCF) (MCF37.0°C 17.0±1.2mm; MCF13.7°C 11.8±0.8mm) in FibTEM. Multiplate analysis revealed a complete loss of platelet function (AUC13.7°C=0% and AUC18.0°C=0%) and a substantially impaired function in moderate hypothermia.

Conclusion: This combined prospective clinical and in-vitro study revealed a substantial hypothermia-related inhibition on coagulation in the multiple trauma patients in an alpine and remote environment. The in-vitro-study showed an impairment of the cellular and humoral coagulation in ROTEM and Multiplate. With point-of-care diagnostics, the impaired coagulation can be quantified and treated more precisely than with the standard coagulation test such as platelet count, INR, and a-pTT. A hypothermic multiple trauma patient requires immediate and aggressive haemorrhage control and rewarming to regain his physiological clotting capacity, timely surgery and point-of-care directed coagulation management. Complete data analysis and discussion will be available for presentation at the EUSEM2017.


Bernd WALLNER (Innsbruck, Austria, Austria), Bettina SCHENK, Markus FALK, Monika BRODMANN-MAEDER, Giacomo STRAPAZZON, Hermann BRUGGER, Dietmar FRIES, Peter PAAL
08:30 - 17:40 #11052 - I DON'T TAKE DRUGS, DRINK ONLY SOLVENT FOR PAINTS.
I DON'T TAKE DRUGS, DRINK ONLY SOLVENT FOR PAINTS.

Personal history and reason for inquiry:

24-year-old male. Syndrome anxious without follow-up from months ago. Treatment with diacepan of irregular shape. Consumer GanmaButirolactona regular for more than one year. Enter 2 days before being transferred to the emergency room in a private drug detoxification Center. They begin treatment with quetiapine + Clorazepato Dipotásico + risperidone + Haloperidol. 36 hours after their stay in the Center it presents picture of agitation psychomotor which fail to control the use of haloperidol, chlorpromazine, and clorazepate DIPOTASSIUM via intramuscular.

 

Physical examination:

Upon arrival TA 130/81. FC: 122 BPM. 93% basal O2 sat. T ° 36.5. Conscious, disoriented, with taquilalia and with incoherent speech. AC: Rhythmic and regulate to 120 BPM. No murmurs, rubbing or extra tones. AR: MVC. No pathologic noise. IN: Reactive Mydriatic pupils. Cranial not assessable by non-cooperation.

 

Evolution and complementary tests:

-          Analytics which highlights Leukocytosis without neutrophilia with elevation of CK to 13.314 u/l and alteration of hepatic profile with AST: 405 u/l and ALT 68 u /l.

-          Toxins in urine positive for benzodiazepines. Negative rest.

-          Rx of portable chest : Normal ICT. Without images of condensation or infiltrated

-          ECG : RS to 120 BPM. QTc: 452 ms Unaltered driving or the Repolarization.

-          TAC skull : radiological study without alterations.

The patient during your stay in the Emergency Department began with decreased level consciousness and appearance of dyskinetic movements. Biperiden is given to maximum doses together with diacepan IV is not controlling the symptoms. It requires sedation with midazolam. After getting control of physical symptoms the patient is assessed by Psychiatry entering voluntarily in the tweeter unit.

 

Clinical judgment:

-          Acute confusing episode.

-          Intoxication by Neuroleptics. Extrapyramidal.

-          Rhabdomyolysis.

 

Conclusions:

The consumption of liquid GanmaButirolactona among young people is a common practice in recent times for being a precursor molecule GanmaHidroxiButirato, GHB or liquid ecstasy. It is marketed in the form of industrial solvent and is easy and cheap acquisition. The emergence of withdrawal symptoms with great physical and psychological symptoms can be observed at three weeks of starting their consumption. Treatment with Neuroleptic withdrawal may worsen symptoms by appearance of extrapyramidal, being the benzodiazepines medication indicated for the treatment of symptoms.


Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO, David NÚÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11053 - I JUST WANTED TO TAKE MY TONSILS AND FINISH WITH MEDIASTINITIS.
I JUST WANTED TO TAKE MY TONSILS AND FINISH WITH MEDIASTINITIS.

PERSONAL HISTORY AND REASON FOR INQUIRY

44-year-old male. Allergy to Penicillins, tetracyclines, streptomycin, no history of interest, 5 days prior to arrival in the Emergency Department is tested in a private Centre tonsillectomy radiofrequency. Discharged the same day of the intervention with ciprofloxacin VO, attends three days later emergency by pain and cervical inflammation with difficulty swallowing. Valued by ORL's guard, is guideline treatment with corticoids VO that do not produce symptomatic improvement, reason by which attends the day following emergency room for evaluation.

 

PHYSICAL EXAMINATION

Patient with good general condition, breathing difficulty. TA: 140/80. FC: 80 lpm. 98% basal O2 sat. Temperature 36.9º

-          Head and neck: bilateral cervical swelling with crackling to palpation with extension to supraclavicular area. Oropharynx with tonsils covered by plates of fibrin without bulging of tonsillar pillars or signs of collection.

-          AC: rhythmic and regular at 80 lpm. No puffs or rods.

-          AR: MVC. No pathologic noise.

 

COMPLEMENTARY TESTS

-          Analytics: highlights Leukocytosis with neutrophilia and rise of the PCR to 228.

-          Cervical TC and thoracic: cervical emphysema, which begins at the level of laryngeal vestibule and extends caudally circumferential way between deep planes of the neck, reaching pre-left brachiocephalic trunk upper mediastinum. In the region immediately posterior to the right thyroid lobe emphysema bubbles are surrounded by a liquid without clear delineation of wall tab. Thickening of the region left tonsillar that imprint in the light of the oropharynx and presents bubbles of emphysema in their thickness. Discreet increase in attenuation of the subcutaneous fat in anterior cervical region.

 

EVOLUTION AND TREATMENT

The patient enters the service charge of ORL which starts treatment with ciprofloxacin + intravenous clindamycin. Given the persistence of fever and no clinical improvement in the patient decides to perform surgical intervention together with thoracic surgery with the following findings: abundant purulent contents in mediastinum previous and upper and deep cervical spaces. Pre larynx necrotic muscle. The patient enters in ICU after the intervention being discharged after 10 days of entry.

 

CLINICAL JUDGMENT

-          Thoracic and cervical emphysema.

-          Secondary Mediastinitis to tonsillectomy radiofrequency.

 

CONCLUSIONS

What initially appears to be a simple intervention with minimum hospitalization and a quick recovery in this case was complicated by the appearance initially cervical emphysema and mediastinum, mediastinitis after requiring joint surgery for thoracic surgery and Ent. Allergy to Penicillins conditioned use of quinolones with clindamycin as a treatment of choice that did not meet the infectious picture in a satisfactory manner.


Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO, David NÚÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11054 - I SMOKED CANNABIS AND END UP TIED TO A STRETCHER.
I SMOKED CANNABIS AND END UP TIED TO A STRETCHER.

PERSONAL HISTORY AND REASON FOR INQUIRY

27-year-old male, habitual consumer of multiple drugs, without psychiatric history recorded except for multiple queries to the emergency room by feeling of nervousness, goes to the emergency room again accompanied his father's feeling of nervousness after having used inhaled cannabis.

 

PHYSICAL EXAMINATION

The patient is restless, diaphoretic, fearful and suspicious before the questions of the nursing staff. TA: 120/80. FC: 150 BPM. 96% basal O2 sat. Afebrile.

-          AC: rhythmic and regular without audible murmurs

-          AR: MVC. Roncus spread both chest.

-          Abdomen: tender and depressible, not painful to palpation.

-          Neurological examination: pupils in reactive Mydriasis. Without other findings.

 

EVOLUTION AND COMPLEMENTARY TESTS

Before the existence of tachycardia decides realization of ECG in nursing triage, moment at which the patient begins with State of agitation psychomotor, incoherent language, sexual deshinibición and auto and hetero aggressiveness.

He is decided this situation the realization of mechanical containment activating the Hospital Protocol with the administration of 10 mg of diacepan and 5 mg IM Haloperidol as well as restraint on mechanical containment stretcher.

Once the patient is less aggressive and more affordable requested additional tests:

-          ECG: sinus without alterations in Repolarization.

-          Analytical blood: discreet Leukocytosis, neutrophilia without reactive.

-          Toxic in urine: positive for cannabis and benzodiazepines.

 

CLINICAL JUDGMENT

Agitation psychomotor secondary to toxic consumption

 

CONCLUSION

After getting with the managed mediation and the mechanical fastening State of agitation of the patient control, it decides containment removal being given patient discharge from the Emergency Department. What initially can be considered a drug use to get relaxing effects, in the case of the patient causing anti-competitive effects. All previous assists the patient to the emergency room for painting of nervousness were characterized by having previously used inhaled cannabis...

Is recommended the patient request help in drug addiction help center to get the drug cessation. 


Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO, David NÚÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11552 - I wish I knew that sooner: the ten essential questions you must ask before redesigning your ED.
I wish I knew that sooner: the ten essential questions you must ask before redesigning your ED.

Building or modernizing an ED is usually a once in a generation opportunity that few clinicians will experience more than once or twice.  Designing an ED right can improve clinical quality and outcomes, enhance operational efficiency, lower the cost of care and create more satisfied patients, visitors and staff.  The challenge with designing a new ED is that no two EDs are alike and even the most qualified of design teams have a learning curve to understand the nuances and culture inherent in every new organization they support.  Successful design is dependent upon ensuring that ED staff and leadership and the design professional are asking the right questions and aligned with the vision and execution of a major design project.  This session will present ten key questions that must be considered at the onset of every ED design project to ensure success.


Manuel HERNANDEZ (Chicago, USA)
08:30 - 17:40 #11594 - I'm tired, I have no appetite and I also have a fever!
I'm tired, I have no appetite and I also have a fever!

Reason of consultation: Asthenia, hemoptysis and fever

Personal history: Allergy to Metamizol and ASA. Bronchial asthma.

Clinic history: A 45-year-old-man who goes to the emergency deparment for a fever of a week of evolution accompained by asthenia, hyporexia, myalgias and polyarthralgia. In the last few days he has commented on cough and dyspnoea on moderate efforts, bloody expectoration, which he has treated with paracetamol with little improvement. In addittion, abdominal distention, fullness, intermittent diffuse pain without constitutional syndrome or nocturnal sweating in previous months. No chest pain, no vomiting and diarrhea. urinary sinus although referring to nocturia for months. Neither cutaneous lesions. 

Physical exploration: Constants vitals: 112/68 100bpm T: 37.4ºC Glucose 150mg St O2 98%  Good general condition, concious, oriented. Skin paleness, mild conjunctival jaundice and dry mucose mebranes. Cardiopulmonary auscultation:  Rythmic without blows, vesicular murmur preserved without added sounds. Abdomen; soft, depressive, non-painful without peritoneal irritation. Neither neurological focal.

Complementary tests: Hemogram; Hemoglobin 10.8 Hematocrit 30% Leukocytes 14000 with predominance of segmented 78% and monocytes. Biochemistry: Creatinine 4.2 urea 128 Glomerular filtration 17ml/m Sodium 129 Potasio 3.1 Chlorine 90 Transaminases: GOT 271 GPT 188 GGT 183 Total bilirubin 3.41  Direct 1.38 Indirect 2.03 Amylase 120 Lypase 152 CPK 4625 Procalcitonin 2.45 Lactate 1.5 Thorax X-ray: without condensation. Abdomen X-ray: normal 

Diagnostic trial: In the presence of acute renal failure and associated methabolic acidosis, mixed hyperbiliruninemia of indirect predominance, hypertransaminasemia, free hempotysis, it was decided to enter into Infectious Diseases Unit such as febrile syndrome and acute renal failure. Probable infection by ricketsia or leptospira. Intensive chemotherapy and empiric antibiotic with Doxycycline are initiated as well as stricted monitoring and control of renal function. Blood cultures anf serologies were taken. During the admission positive serology was confirmated for leptospira anf fiberoptic bronchoscopic with diffuse alveolar hemorrhage. Weil's Disease (Leptospirosis icterohemorrhagic with renal involvement and pulomnary hemorrhage). In addition to therapy, ceftriaxone and doxycycline were initiated. He needed blood transfusion for severe anemia. After one month he was discharged with clinical improvement. 

Conclusions: Weil's Disease is transmitted by rodents and ¡ts clinical range varies from common cold (fever, headache, myalgias) to jaundice, vomiting, intestinal or pulomnary hemorrhage, dyspnoea anf renal failure resulting in mortality. Microaglutination (MAT) is gold standard although serological confirmation is required. The treatment of choice is penicillins and tetraciclines (Doxycycline), in severe leptospirosis is combined cefalosporin 3rd generation and doxycycline.


Barbara MARTIN GINER, Eduardo RIOL LÓPEZ (Las Palmas de Gran Canaria, Spain), Francisco SOSA PÉREZ
08:30 - 17:40 #10950 - Identification of risk factors in patients with non-specific chest pain.
Identification of risk factors in patients with non-specific chest pain.

Background

Patients referred to Emergency departments (ED) and Cardiology departments (CD) with acute chest pain represents a large proportion of patients seen in these busy departments and is the 5th most prevalent chief complaint in the ED in the Region of southern Denmark. Several risk score tools have been developed for the purpose of risk stratification of chest pain patients. Previous studies have reported the mortality and risk of cardiac event in patients excluded for myocardial infarction. However the sub group of patients without diagnosis-the non-specific chest pain group is largely unexplored - especially after the implementation of   (hstn).  But this group compromises up to 50% of all chest pain contacts and finding those with increased risk of cardiac event is crucial.

 

The aim of this study was to assess the frequency of adverse cardiac outcomes in a 12 months period among patients acutely referred to hospital due to chest pains after the implementation of the new hsTn and where myocardial infarction has been ruled out.  Furthermore to identify those with an increased risk of an adverse outcome

Method

Prospective multicenter cohort study among 18-70 years old patients, with an emergency visit to the hospital, and has at least one troponin test performed during their visit. The patients without troponin elevation and no obvious other reason for the chest pain wasthe NSCP group of interest and wascontacted for a telephone interview with a standardized questionnaire concerning the patient's symptoms, background, use of medication etc. Clinical information including ECG, essential information on blodpressure, pulse, respiratory frequency at arrival and echocardiography was gathered from the patient file. Outcome data was obtained from the National Patient Register (LPR) and from the Civil Registration System (CPR) and reported for 12 months follow up or emigration.

Results: 1036 patients were included for analyses.  Study population had a median age of 54 years and consisted of 55% women. During one year follow up 9 patients died of not cardiac- related- medical causes. 17 patients had an revascularization, two patients had an MI and 4 was diagnosed with unstable angina pectoris (UAP). The risk of future cardiovascular disease was calculated with cox regression and was based on the association between HR and revascularizations and MI as deaths were not cardiac related.

Significant values were found for the exposure variables male gender (HR=5.3), BMI>25(HR=5.3), ) previous diagnosis of IHD (HR=3.9), and comorbidities as hypertension (HR=5.0), diabetes (HR 5.6) or hypercholesterolemia (HR=4.7) as informed by the patient. The use of cholesterol lowering medication were also significant (HR=4.6). 

Conclusion

The prognosis regarding IHD in NSCP group is good, and this study implies that patients with increased risk of IHD are properly stratified at index admission


Nivethitha ILANGKOVAN, Pr Christian Backer MOGENSEN (Aabenraa, Denmark), Axel DIEDERICHSEN, Annmarie LASSEN, Hans MICKLEY
08:30 - 17:40 #10970 - Ileo biliary with proper name.
Ileo biliary with proper name.

CLINIC HISTORY:

• Personal history:

Intolerance to TRAMADOL. HTA, DM type 2, dyslipidemia. Appendectomy.

• Anamnesis:

A 79-year-old patient who had a post-prandial vomiting of about 48 hours, also had right hypochondrium pain in the last hours. Constipation in the last 4 days, although it is usually constipated.  Deny fever. Deny another clinic.

• Exploration: TA 130/50. Temperature 37.1 ° C. Basal O2 saturation: 97%. CyO. Well hydrated and perfused. Affected general condition. Eupneic. ACR: rhythmic and regular tachycardia without blows or extratons. Preserved vesicular murmur. Abdomen: Large scar in right iliac fossa. Not hernias. No masses or megalias. Abdominal defense predominated in right hemiabdomen. No other findings in exploration.

• Supplementary tests:

  - Blood analysis: highlights leukocytosis 22500 (91.6% neutrophils). Glucose 259 mg / dl, Creatinine 1.57 mg / dl. No alterations in liver profile. PCR 296.

  - Rx abdomen: There is a certain dilation of thin handles, scarce presence of feces and distal gas. Image of calcium consistency in the middle zone of right hemiabdomen. Before the suspicion of possible bile ileus is requested CT of the abdomen.

  - TAC abdomen: Very distended gallbladder with parietal thickening and pericolecular fluid, increased attenuation of adjacent fat, as well as liquid in the droplet. Adjacent, a calcium image of probable lithiasis is observed, without being able to identify if it is located distal to the infundibulum or in the first portion of the duodenal loop. Rotation of the duodenal frame is observed.

  - Upper digestive endoscopy: In the stomach there is abundant biliary content with vegetable remains. Impacted biliary calculus is observed in postpilic region that can not be extracted with a congestive wall.

EVOLUTION:

Given the characteristics of the patient, surgical intervention is chosen extraction of 3x4 cm by duodenotomy, evidencing cholecystoduodenal fistula. It is decided not to repair fistula or cholecystectomy. Intravenous antibiotic therapy is performed with amoxicillin-clavulanic, reintroduction feed around the week. It presents good evolution, being discharged in 20 days with follow-up in consultation for assessment of programmed cholecystectomy.

COMMENTARY:

Bouveret's syndrome is defined as the impaction of a biliary calculus at the pyloricoduodenal level. The main cause of this syndrome is the bilio-digestive fistula that allows the passage of stones from the gallbladder (usually greater than 25 mm). The diagnosis is made by imaging tests where the abdominal CT provides the best evaluation, being High Digestive Endoscopy that confirms the diagnosis. The first step in the treatment is the stabilization of the patient and we will always try to remove the lithiasis for which we have endoscopic or surgical treatment. Generally enterolithotomy is the appropriate initial treatment due to the Urgent nature of the clinical picture and the advanced age of many of these patients.


David NUÑEZ CASTILLO (SPAIN, Spain), Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO
08:30 - 17:40 #11733 - iliofemoral deep venous thrombosis (DVT), a rare presentation caused by Psoas muscle desmoid fibromatosis. Case report.
iliofemoral deep venous thrombosis (DVT), a rare presentation caused by Psoas muscle desmoid fibromatosis. Case report.

Background:

DVT is a frequent disease that carries a high risk for complications that could be life threatening. Iliofemoral (IF-DVT) is considered to be more serious than DVT of the lower limb that is infra-inguinal. It carries a higher risk of pulmonary embolism, limb malperfusion, and post-thrombotic syndrome. IF-DVT accounts for 25% of all lower extremity DVTs. Anatomic predisposition is considered to be the major reason behind the formation of IF-DVT, along with other risk factors for venous thrombosis. Intra-abdominal mass at the iliac level is a rare cause of developing DVT.

Desmoid-type fibromatosis (DF) is a rare type of benign (non-cancerous) tumor. DF is cytologically bland fibrous neoplasm originating from the musculoaponeurotic structures throughout the body. It is a locally aggressive type of tumors that are reported to account for 0.03% of all neoplasms.  It is more frequently seen in females between the age of 10 to 40 years old. We are reporting a rare case of IF-DVT that was secondary to psoas muscle DF.

Case presentation:

27 years old female presented to the emergency department by right lower limb swelling for 5 days. The patient denies any past medical illness. She denies also being on any current medications or oral contraceptive pills.

She had no recent travel history, trauma or any risk factors for thromboembolic disorders. She was nonsmoker nonalcoholic and had no previous episodes of deep venous thrombosis DVT. The patient was vitally stable afebrile, with only recent history of vague nonspecific abdominal pain for 1 week.

Her physical examination revealed, swollen right lower limb with intact distal pulsation and neurological exam. She had soft and lax abdomen with right inguinal enlarged non-tender lymph nodes.

Initial blood work up came later as normal values including complete blood picture and coagulation profile. She was sent for venous ultrasonography of the lower limbs which reported as no evidence of DVT or collection with compressible all right lower limb veins.

The patient had a CT scan later with intravenous contrast that showed a fairly well-defined soft tissue mass likely arising from the lower part of the right psoas major muscle and partially encasing external iliac vessels with thrombosis of the femoral vein and external iliac vein with multiple enlargement lymph nodes in the superficial and deep inguinal group.

The patient received medical treatment of DVT. Tissue biopsy revealed later a picture of spindle cell lesion, favors desmoid- type fibromatosis.

Conclusion:

IF-DVTs are a rare form of lower extremity DVT that holds a potentially life-threatening complication, intra-abdominal mass like DF is one of the reasons that can lead to it.


Mohamed Yassin MITWALLI, Sherif ALKAHKY, Abdalrahman Ahmed ABOSLEMA, Mohamed QOTB, Dr Ziad ALHARIRI (Doha- Qatar, Qatar)
08:30 - 17:40 #10834 - Impact assessment of mass gatherings using labelling procedure in emergency department, Nouvelle-Aquitaine, France, 2016.
Impact assessment of mass gatherings using labelling procedure in emergency department, Nouvelle-Aquitaine, France, 2016.

Objective: To access the potential health impact on the population during mass gathering over time using labelling procedure in emergency department (ED).

Introduction: The massive flow of people to mass gathering events, such as festivals or sports events like EURO 2016, may increase public health risks. In the particular context of several terrorist attacks that took place in France in 2015, the French national Public Health agency has decided to strengthen the population health surveillance systems using the mandatory notification disease system and the French national syndromic surveillance SurSaUD®.

The objectives in terms of health surveillance of mass gathering are: 1/ the timely detection of a health event (infectious cluster, environmental exposure, collective foodborne disease…) 2/ the health impact assessment of an unexpected event such as a terrorist attack.

In collaboration with the Regional Emergency Observatory (ORU), a procedure for the labeling of emergencies has been tested to identify the ED records that could be considered as linked to the event.

Methods: During summer 2016, the procedure was tested on seven major festive events throughout the region. In addition to the main medical diagnosis, a specific ICD-10 code “Y3388” was chosen to be used in associated diagnosis for records that were supposed to linked to the event.

Information on the labeling procedure was insured by the ORU to the emergency departments.

All records with medical diagnoses or medical pattern beginning by Y33 have been analyzed.

Results: No significant increase in the global indicator was observed in the ED impacted by mass gathering. The ED labelling procedure identified 260 records: two thirds corresponded to young men and 17% came from abroad. Among the 250 records labeled in associated diagnosis, 39% were associated to traumatisms and 31% corresponded to alcohol intake.

Conclusions: This study shows that a labelling procedure allows the identification, quantification and characterization of the population ED records associated with mass gathering. Additionally, a labelling procedure to assess a potential impact of an event as mass gathering can be implemented fairly rapidly.


Laure MEURICE (Bordeaux), Caroline LIGIER, Anne BERNADOU, Antoine TIGNON, Patricia SIGURET, Stéphanie VANDENTORREN, Céline CASERIO-SCHÖNEMANN, Laurent MAILLARD
08:30 - 17:40 #11936 - Impact of hyperchloremic mineral acidosis during the treatment of diabetic ketoacidosis in emergency department.
Impact of hyperchloremic mineral acidosis during the treatment of diabetic ketoacidosis in emergency department.

Background:

Hyperchloremic mineral acidosis (HMA) is a frequent complication of the treatment of diabetic ketoacidosis (DKA). Its etiopathogenesis relies on the administration of large volumes of saline solutions for resuscitation and increased proximal tubular reabsorption of chloride as less bicarbonate becomes available. The aim of this study was to evaluate the incidence of this therapeutic complication and its impact during the management of DKA in emergency department.

 

Methods:

Prospective descriptive study over 30-month period including patients aged > 16 years admitted to the emergency department for moderate to severe DKA. Standardization of DKA management occurring to ADA recommendations: fluid resuscitation with normal saline solution, insulin therapy and replacement of electrolytes.

HMA was defined as: pH<7,38, HCO3-105 mmol /l and absence of ketone bodies.

 

Results: 

We enrolled 140 consecutive DKA patients. The mean age was 36+/-16.5 years with a sex ratio of 0.77. Medical history, N (%): type 1 diabetes, 78 (56); type 2 diabetes, 47 (33.4); inaugural, 18 (13). Usual treatment, N (%): insulin, 114 (81.4); biguanides, 10 (7); sulfonylureas, 9 (6.4). Thirty-seven patients (26.4%) developed HMA during the management of DKA with a mean delay of 12 +/- 4.8 hours, delta AG=15 +/- 5, delta HCO3=7.3 +/- 4 and delta CL=12 +/- 4.6. The group with HMA complication needed higher dose of insulin to recovery (88 vs 60 units; p=0.003), higher dose of 5% dextrose solution (1.6 vs 1.2 L; p=0.001) with prolonged delay to resolution of acidosis ( 19 vs 11 hours; p=0.000). Hypokalemia was more frequent in the group of HMA (p=0.003). The lengths of stay in intensive care unit and in hospital were longer in the HMA group.

 

Conclusions:

HMA during fluid therapy by normal saline solution was documented in 26.4%. It remains a frequent complication and it is not surprising that hyperchloremia retards the increase in bicarbonate and pH and, consequently, increase the occurrence of others complications such as hypokaliemia, tends to prolong IV insulin infusion time and ICU stay. Rehydration with balanced solutions could prevent this complication and reduce the cost of hospitalization. 


Fatma HEBAIEB (Ariana, Tunisia), Sarra JOUINI, Amina JEBALI, Dorra CHTOUROU, Amel MAAREF, Imen MEKKI, Alaa ZAMMITI, Chokri HAMOUDA
08:30 - 17:40 #11545 - Impact of standardized pathway on patients presenting with neck of femur fractures; an audit.
Impact of standardized pathway on patients presenting with neck of femur fractures; an audit.

Abstract

Background

The incidence of femoral neck fractures is expected to rise with life expectancy. It is important to improve the safety of these patients 1. It has been see that implementation of standardized pathways of care for such patients not only improves patient care but also improves compliance with national and international standards 2.

Introduction

We present the findings of an audit that was done to evaluate the care of patients presenting with neck of femur fractures before and after implementation of National Neck of Femur Pathway (NOFP). Variables that were looked at included ‘Time taken to be seen in emergency department’, ‘time to administration of analgesia’, ‘time to x-ray’, and ‘time to hospital discharge. First cycle of audit was done 1 year prior to implementation of the NOFP. The variables were audited again 6 months after implementation of the NOFP.

Findings

After the introduction of NOFP, all the patient care variables improved. Time to be seen in emergency department improved from a mean on 160 minutes to a mean of 90 minutes. Time to administration of analgesia improved from a mean of 200 minutes to a mean of 120 minutes. Time to imaging improved from a mean of 210 minutes to a mean of 126 minutes. Average discharge time improved from 19 days to 16 days.

Conclusion

Standardized care pathways like National Neck of Femur Pathway not only improve patient care but also result in a reduction of average length of inpatient stay.

 

References

 

 

1.            Agha R, Edison E, Fowler A. Improving the preoperative care of patients with femoral neck fractures through the development and implementation of a checklist. BMJ Qual Improv Rep. 2014;3(1).

 

2.            Chamberlain M, Pugh H. Improving inpatient care with the introduction of a hip fracture pathway. BMJ Qual Improv Rep. 2015;4(1).

 


Mustafa MEHMOOD, Abdullah Rauf RANA (Drogheda, Ireland), Miqdad Raza LAKHANI
08:30 - 17:40 #11788 - Impact of Teamwork and Communication Training Interventions on Safety Culture and Patient Safety Outcomes in the Emergency Department: a systematic review.
Impact of Teamwork and Communication Training Interventions on Safety Culture and Patient Safety Outcomes in the Emergency Department: a systematic review.

Introduction: In #To Err Is Human#, the Institute of Medicine highlights the importance of teamwork and communication, and building a culture of safety as a prerequisite to improving healthcare quality and reducing patient harm. 

Objectives:

The principal objective of our study was to systematically review the literature that analyzes the impact on patient safety culture of teamwork and communication improvement interventions in the emergency department (ED).

Methods: We identified studies in PubMed, Cochrane Library, Medline, Embase, PsycINFO, CINAHL, Web of Science and Educational Resources Information Center up to December 2016. 

Results: We screened 5,453 publications and selected 13 studies with moderate risk of bias. Study design, and evaluation method varied widely. The method of evaluation used in all studies was a Pre-and After intervention. Simulation was used in 8 studies, crisis resource management training in 3 studies, team course program in 2 studies. Interventions showed a significant improvement on communication (p<0.05, n=7 studies), leadership (p<0.05, n=6 studies), teamwork (p<0.05, n=2 studies). In one study, intervention decreased significantly (p<0.05) the number of adverse events in the ED. Because we found a high heterogeneity, a meta-analysis was not possible.

Conclusion: Overall, this systematic review showed that interventions can improve patient safety culture in the ED in three domains, communication, leadership and teamwork. Culture safety training programs must be implemented in the ED to decrease the number of medical errors and adverse events.


Mohamed ALSABRI, Gregoire VERSMEE (Boston, USA), Julia WHELAN, Dominique LAUQUE, Michel PHILIPPE, Pauline HAROUTUNIAN, Nnamdi NWAUWA, Karim TAZAROURTE, Martin MOECKEL, Anna SLAGMAN, David BATES, Shan LIU, Carlos Arturo, Jr CAMARGO, Singer SARAH, Jonathan EDLOW, Richard WOLFE, Pr Abdelouahab BELLOU
08:30 - 17:40 #11683 - Impact of using low-dose methoxyflurane on time from arrival of paramedic / emergency assistance to first pain relief treatment versus other pain medications in Australia.
Impact of using low-dose methoxyflurane on time from arrival of paramedic / emergency assistance to first pain relief treatment versus other pain medications in Australia.

Background

Acute pain remains highly prevalent in both the pre-hospital and Emergency Department.1, 2 As emergency department waiting times and delays in paramedic-to-nurse handover increase, it becomes more and more vital that patients receive adequate pre-hospital pain relief.3 However, administration of analgesia can be inadequate and can result in patients experiencing oligoanalgesia, or under-treated pain.3

Low-dose methoxyflurane (LDM), self-administered by the patient via a handheld inhaler (Penthrox®) is a fast-acting, non-narcotic analgesic agent that has been used in Australia and New Zealand for over 30 years.

The aim of this study is to compare the time from arrival of paramedic / emergency assistance to first pain relief treatment using LDM versus other pain medications in Australia.

Methods

A retrospective chart review was conducted to understand pain relief treatments, timelines and outcomes in medical emergency situations across Europe and Australia.  The LDM data presented is solely from Australia, where it is considered part of the standard of care.

A total of 48 emergency specialists reviewed 246 patient charts in Australia (128 patients receiving LDM as their first analgesic and 118 receiving other pain relief).

Propensity score matching was used to match 85 LDM and non-LDM patients from each group.  Clinicians reported from patient charts, which included ambulance and hospital notes, the time from arrival of paramedic / emergency assistance to first pain relief treatment.

The study was conducted in compliance with the protocol and the Code of Conduct of the Australian Market & Social Research Society.

Results

The mean (SD) time from paramedic / emergency assistance to first pain relief treatment in the LDM treated group was 21.7 minutes (24.24) vs. 39.1 minutes (42.95) in the non- LDM (p-value 0.0013).  The median was 12.0 minutes (interquartile range (IQR) 6.0 – 28.0) in LDM vs. 21.0 (IQR 9.0 – 60.0) in the non-LDM group.

Discussion

This study demonstrates that the use of LDM is associated with significant lower time from paramedic / emergency assistance to first pain relief treatment vs. non-LDM patients.

Shorter time to analgesia administration is associated with reduced patient suffering in relation to trauma, improved patient care and satisfaction. It further allows for faster mobilisation and transfer of patients to the hospital which may lead to improved patient flow and throughput.

References

  1. Berben SA, M, et al. Pain prevalence and pain relief in trauma patients in the Accident & Emergency department. Injury. 2008;39(5):578-585.
  2. Berben SAA, et al. Prevalence and relief of pain in trauma patients in emergency medical services. The Clinical Journal of Pain. 2011;27(7):587-592.
  3. Parker M, Rodgers A. Management of pain in pre-hospital settings. Emerg Nurse. 2015;23(3):16-21; quiz 23.

®PENTHROX is a registered trademark of Medical Developments International

This study has been funded by Mundipharma International Ltd


Andrew XIA, Will DUNLOP, Sara DICKERSON, Sam COLMAN, Agota SZENDE (Leeds, United Kingdom)
08:30 - 17:40 #11326 - Implementation of a Chlamydia and Gonorrhea Screening Program in an Urban Emergency Department Setting.
Implementation of a Chlamydia and Gonorrhea Screening Program in an Urban Emergency Department Setting.

BACKGROUND: Chlamydia and gonorrhea (GC/CHL) are two of the most common sexually transmitted diseases in the United States with one of the highest reported prevalence and incidence rates in New York City. Women between ages 15 and 24 are disproportionately affected and prone to serious morbidity, including Pelvic Inflammatory Disease and infertility. The primary objective of this study is to improve GC/CHL screening and treatment for the at-risk population. The secondary objective is to estimate prevalence and assess risk factors of the target population.

METHODS: A GC/CHL screening program was implemented in the Adult and Pediatric Emergency Departments (ED) for a six-month period. Using a unique public health model, baseline screening performed by ED providers was augmented with Public Health Advocates (PHA), targeting women in the high-risk age cohort. PHAs approached the target population, regardless of chief complaint for GC/CHL screening. For those who agreed, a urine specimen was collected for diagnostic testing and sexual counseling was performed. Two full-time nurse practitioners contacted those with reactive results by phone or Mailgram. Those who were not presumptively treated were asked to return to the ED for treatment. Of those screened, a convenience sample of surveys assessing risk factors and sexual history was collected.

RESULTS:  The collective screening coverage reached 14.9% (834/5,591) of the target population from January 1st, 2016 until June 30th, 2016. The chlamydia positivity rate was 18% (27/149) and the gonorrhea positivity rate was 3% (4/149). Treatment rates were 87% for chlamydia and 100% for gonorrhea cases. Of those screened, 118 participants completed the survey. 60% were Hispanic and 33% were African American, which is similar to the baseline demographics for the EDs holistically. Risk factors, as per CDC criterion, included: inconsistent condom use (85.2%), multiple sex partners (28%), and ever had an STD (20.3%).

CONCLUSION: Although screening coverage was relatively low, the program captured a high risk population as reflected by the high positivity rate for both chlamydia and gonorrhea. Exceptionally high treatment rates were achieved. Correlation between risk factors and positivity could not be calculated due to a low survey sample size. However, the program will assess this correlation and identify symptomatic cases over the next 6 months.


Ethan COWAN (New York, USA), Yvette CALDERON, Jason LEIDER
08:30 - 17:40 #10248 - Implementation of a specific pathway for disabled patients in the Emergency Department.
Implementation of a specific pathway for disabled patients in the Emergency Department.

Introduction: the care of a disable patient in the French Health System was identified as a priority at the French national conference on disability. According to National data, only15% of French Hospitals can provide accessibility to disabled patients. Improving the care of disabled patients in Emergency Department (ED) requires a reorganization of the patient flow and specific tools for communication. We have set up a working group on the care path for the disabled patient.

Materials and methods: Based on results of a national on-line survey carried out from November 2015 to September 2016 assessing the quality and satisfaction of Frenchs ED by disabled patients and their representatives, we implemente a clinical pathway for disabled patients in the ED.

RESULTS: More than 3000 responses to the questionnaires were analyzed. The inpatient flow in the ED is frequently described as traumatic by disabled patients and accompanying persons. The main points of improvement concern the communication tools (deaf and dumb language), the need to have a specific liaison file, lack of evaluation of pain and anxiety. The care pathway in the ED should allow the anticipation of the arrival of the patient from the Nurse Triage zone,  fluidification of the flow process and permanent integration of the accompanying person in order to limit the waiting time perceived as traumatic and generating agitation or aggression. Implementatiuon of a specific trolley allows caregivers and accompanying persons to dispose of the first-aid care equipment.

Discussion:
The French National Health System is actually working on a new draft for the care of disabled patients. According to the results of the questionnary on disabled patients needs, the first step was to reorganize the flow process in our ED with a fast-track pathway from the entrance to admission in the Short Stay Unit (SSU) adapted to the care of disabled patients. Implementation of specific communication tools, specific liaison card and a mobile and specific care trolley dedicated to the comfort and gestures of the disabled patient. A call for recruitment of internal resources of our hospital and inventory of skills of caregivers was carried out. A complementary work on the path of care of the disabled patient in medical, surgical, pediatrics departments in our hospital is currently in progress as well as a creation of consultation dedicated to the care of the disable patient.  The next step will evaluate the specific impact on workflow, waiting time, specific indicators (pain , anxiety and satisfaction rates) with 6 other pilots emergency departments.

Conclusion: The analysis of satisfaction questionnaires for disabled patients prompted us to review our practices and our organization within the ED in order to improve our specific care for fragiles, anxious patients and the development of a communication tool. The next step in 2017-2018 will set up a French pilot study with 6 University and General Hospitals.


Eric REVUE (Paris), Alexandre HENNIART, Amine ABDALLAH, Gaelle LAVIE-SALOMON, Lucille DUMOULIN, Emilie RIVIERE, Pascal JACOB, Monique TITTON
08:30 - 17:40 #11471 - Improved compliance to trauma alert criteria may optimize patient safety with sustained low undertriage.
Improved compliance to trauma alert criteria may optimize patient safety with sustained low undertriage.

Objectives

To evaluate trauma alert criteria regarding compliance, under-and overtriage and identify riskfactors for mistriage.

Methods

In a retrospective cohort study, all consecutive surgical trauma patients at a university hospital in 2012 were included. Patients were stratified into three groups based on trauma team activation (full trauma team, limited trauma team and no trauma team). Case records were reviewed for mechanism of injury, vital signs and injuries. Compliance to alert criteria was evaluated and injury severity score combined with the Matrix method was used for assessment of over- and undertriage.

Results

A total of 1424 surgical trauma patients were included in the study. Seventy-three patients (5.1%) activated a full trauma team, 732 (51.4%) a limited trauma team and 619 (43.5%) did not activate any trauma team. Undertriage was 2.7% (95% CI 1.9–3.8%) and overtriage 34.2% (95%CI 23.5–46.3%) in the complete cohort. Compliance to alert criteria was assessed by comparing initiated alert with the indication for trauma alert based on pre-hospital case records. Compliance to full trauma team criteria was 80% (68–88%), limited trauma team 54% (51–58%) and no trauma team 79% (76–82%). Assuming full compliance to trauma criteria, the Matrix method resulted in an undertriage of 2.3% (95% CI 1.6–3.3%) and an overtriage of 42.6% (95% CI 32.4–53.2%) with a 21% reduction in initiated alerts.

Conclusions

The over- and undertriage in this study is in line with the recommendations of the American College of Surgeons Committee on Trauma. However, better compliance to trauma alert criteria would result in fewer trauma team activations without affecting patient safety.


Fredrik LINDER (Uppsala, Sweden), Lina HOLMBERG, Martin BJÖRCK, Hampus EKLÖF, Claes JUHLIN, Kevin MANI
08:30 - 17:40 #11625 - Improvement of Skills in Cardiopulmonary Resuscitation of Residents by Real-time Feedbacks.
Improvement of Skills in Cardiopulmonary Resuscitation of Residents by Real-time Feedbacks.

Background: It is clear that high-quality cardiopulmonary resuscitation(CPR) is a key step to success of return of spontaneous circulation in cardiac arrest patients. Basic life support Training of first year residents is essential. The purpose of this study was to evaluate the effectiveness of a real-time feedback system compares to a debriefing report feedback and traditional standard instructor feedback for CPR in the first year residents.

Methods: To provide basic life support study materials and teaching video for residents’ self-study in one day ahead of training. 90 residents were measured of the BLS theoretical level and the skills before the training course beginning. And then 90 residents were randomized to three groups of CPR training: 1) using real-time feedback system (Real-time feedback group-30 residents) during CPR with the guide of an instructor 2) based on debriefing reports feedback by instructor (Debriefing reports group–30 residents). 3) traditional standard instructor feedback group (Traditional standard instructor group). All groups had 5 cycles CPR performance training. We assessed all residents after 6 hours practice with a whole 5 cycles CPR session and the theoretical level.

Result: Comparing pre-test to post-test results showed an overall improvement in skills and BLS scores after the training program in three groups. Residents in Real-time feedback group had a significantly higher compression score compared to Debriefing reports group and Traditional standard instructor group. Residents in Real-time feedback group performed significantly higher percentage of fully recoil chest compressions, best chest compression rate and best compression depth compared to other two groups.

Conclusion: BLS training session based on a real-time feedback system guided by a teacher is better than based on debriefing reports feedback or traditional standard instructor feedback group in terms of CPR technical skill training among the first-year residents.


Xianjin DU (CHINA, China), Dan TIAN, Jie WEI
08:30 - 17:40 #11899 - Improvement Project of Recognition and Management of Acute Angioedema in the Emergency Department.
Improvement Project of Recognition and Management of Acute Angioedema in the Emergency Department.

Introduction

20% of population will have an Acute Angioedema episode in any time of their life.

This disease is interesting because of its heterogeneous symptomatology, its potential gravity and its need of an early and specific treatment.

In order to reduce the variability in its management, a protocol was proposed.

Material and Method

The objective was adapting the management of Acute Angioedema in the Emergency Department to the very best scientific literature available.

Therefore a protocol was made, with an algorithm for diagnosis ant treatment decision.

Four quality indicators were proposed for monitoring and implementing this protocol.

Results

Three periods were differentiated in the measurement of quality indicators: 1º previously, 2º during and 3º after the implementation of this protocol:

1-    Proportion of patients referring acute angioedema with appropriated anamnesis. Respectively: 50%, 58, 33% y 77,96%.

2-    Proportion of patients transferred to Alergology Department: 50%, 53, 96% y 69,18%.

3-    Proportion of patients treated with antibradicinergic drugs when antihistaminics didn´t work: 0%, 1, 38% y 13, 55%.

4-    Proportion of patients with previous diagnose of angioedema, who received an appropriated treatment: 20, 4%, 27,4% y 90%.

Discussion

The results shown in the three different periods bring to light a final improvement after a more problematic initial situation, therefore, there is a quality upgrade.


Teresa ESCOLAR (ZARAGOZA, Spain), Miguel RIVAS, Amparo CANTÍN, Silvia CASTÁN, Carmen LAHOZA, Daniel SÁENZ, Inés MURILLO
08:30 - 17:40 #11416 - Improving patient and provider experience in the emergency department using an artificial intelligence triage application.
Improving patient and provider experience in the emergency department using an artificial intelligence triage application.

Background:  Emergency department (ED) crowding is a well-recognized and worsening problem for patient care in the United States. This places pressure on the clinical providers overseeing the waiting area where patients regularly wait multiple hours for care.  Significant variability exists in the type of ED triage systems employed in the EDs in the US, and predictive analytic techniques integrated within ED triage tools may help improve wait times and patient outcomes when employed early in the ED stay. 

Methods: We collaborated with Vital Software, Inc., to develop and test the usability of a novel, secure, web- and mobile-based triage and patient/provider communication program called My ED, which augments the existing triage system of an ED.  We used artificial intelligence and natural language processing techniques to predict important clinical outcomes: hospital admission, same-day surgery, same-day cardiac catheterization lab, intensive care unit admission, medications prescribed, and procedures performed.  We built communication tools within My ED to improve task-based care coordination in the ED by connecting patients with their clinical providers throughout the ED stay.  We also conduced usability testing among n=20 users to ensure functionality of the tool.

Results:  The My ED application has both patient-facing characteristics as well as clinical provider-facing characteristics. The patient facing application offers the patient an easy-to-use, clear, clean data entry process for patient reported information (Figure 1). The application distills meaning from free-form text entered by the patient. When combined with additional demographic and clinical information gathered during the triage process, this helps to predict multiple outcomes, such as hospitalization risk (c-statistic = 0.84). In addition to the predictive capacity of the triage tool, My ED also offers streamlined patient check-in, reduces redundancies in patient/clinician questioning, and ensures a patient-centered approach where patients can send quick and secure messages to the clinical team throughout the ED stay. The provider-facing side of the triage application offers a multitude of patient care tools, such as a view of all patients currently in the ED, an advanced search function, and a view of predicted and suggested labs, tests, medications, likelihood of admission, vitals, insurance information, a picture of the patient, an automatically generated history of present illness, and expanded chat.  Patient-level data is editable by providers, and providers can communicate with the care team through the application in addition to communicating with the patient.

Conclusion:   We developed and tested the usability of the My ED tool and found that it is feasible for pilot testing in clinical practice. A larger randomized controlled trial is planned for Fall 2017. The My ED tool could help to improve patient satisfaction and increase ED efficiency.


Justin SCHRAGER, Rachel PATZER, Aaron PATZER, Justin SCHRAGER (Atlanta, USA)
08:30 - 17:40 #11205 - Improving the care pathway for patients with mental health problems presenting to the Emergency Department.
Improving the care pathway for patients with mental health problems presenting to the Emergency Department.

Introduction:

A historical deficit in parity of esteem for mental health (MH) conditions has translated to inadequate use of established care protocols for patients with MH conditions in some Emergency Departments (ED), resulting in sub-optimal care. The Royal College of Emergency Medicine guidelines state that all patients with a MH presentation must have a Mental State Examination (MSE) performed and documented. The use of a MH pro-forma, such as an integrated care pathway, improves documentation of key findings that informs risk for MH patients and therefore improves the care pathway for these patients.

 

Aim:

Our aim was to improve MSE documentation for all patients presenting to the ED at St Thomas’ Hospital with MH conditions. Mental Health Integrated Care Pathway (MHICP) usage was assessed as a secondary outcome.

 

Methods:

All patients presenting to the ED with a MH condition as their primary complaint were included in the study. Initial audit established baseline MSE documentation rates and MHICP usage over a two week period. Two Plan-Do-Study-Act (PDSA) quality improvement cycles were performed, each over a two week period, first with education and reminders and second by improving access to necessary documents. MHICP usage and MSE documentation rates were audited before and after each PDSA cycle.

 

Results:

The number of cases that met our eligibility criteria in each two week audit ranged from 40 to 53. For each audit, the cases were randomised and 30 cases were included in results. Baseline rates of MSE documentation and MHICP usage were 16.67% and 26.67% respectively. Cycle 1 saw an improvement in MSE documentation to 33.33% (100% relative increase) and in MHICP usage to 46.67% (75% relative increase). Further improvements were seen during the second PDSA cycle; overall MSE documentation improved from 16.67% to 46.67% (180% relative increase) and MHICP usage improved from 26.67% to 56.67% (112% relative increase).

 

Conclusions:

It is known that by increasing MHICP usage and MSE documentation, patients presenting to the ED with MH conditions receive improved care. This study highlighted that simple measures such as education and improving access to documents can lead to substantial improvement in documentation rates. Reasons why a greater improvement was not seen include direct referrals to Liaison Psychiatry, experienced members of staff following MHICP principles without documenting and disruption due to ongoing refurbishment in the ED. Further avenues for improvement include integrating the MHICP into the main clerking sheet and the use of prompts on the computer system to remind staff to document the MSE.

 

References:

  1. The College of Emergency Medicine (2013) Mental Health in Emergency Departments - A toolkit for improving care. [online].
  2. NCEPOD (2017) Treat as One. Bridging the gap between mental and physical healthcare in general hospitals. [online].

Claire LLOYD (London, United Kingdom), Mehul SHAH, Daniel TURK, Vivek SRIVASTAVA
08:30 - 17:40 #10682 - Improving waiting times for mental health patients in the emergency department.
Improving waiting times for mental health patients in the emergency department.

Mental health complaints form a large proportion of the emergency departments’ workload. Patients are often distressed; therefore timely assessment is crucial to their successful management. Recently, several studies have raised concerns about the quality of care for this patient group.

Trakcare was used to identify 307 patients presenting to the Royal Alexandra hospital (Paisley) and Inverclyde Royal hospital (Greenock) between 1st July-30th Sept 2016 .

In our ED, mental health patients are triaged as category 2, meaning they should be assessed within 10 minutes. A proforma is completed by the triage nurse and then by the ED doctor.  If required, further assessment by CPNs can be requested. This study aims to look at compliance with mental health proformas, the waiting times experienced by mental health patients, and to determine the outcome of CPN reviews.

Proforma compliance was achieved 100% of the time by nurses compared to 38% by doctors. On average, patients waited 192 minutes from registering in the Emergency Department until being discharged. Patients waited an average of 64mins for review by an ED doctor. 33% of patients were referred to the CPNs.  The average time taken from registering in the ED to being assessed by a CPN was 195 minutes.

Psychiatric patients attending the ED are waiting unacceptable times to be assessed by our CPN colleagues. We hope by highlighting these excessive waiting times that this paper will contribute to improving mental health services for patients presenting to the ED.

 

 


Barry MCLAUGHLIN (Glasgow, United Kingdom), Paul MCNAMARA, Robyn MORRISON
08:30 - 17:40 #11829 - In Situ Simulation in the Pediatric Emergency Department for pediatric residents: first results of a training project focusing on pediatric severe trauma.
In Situ Simulation in the Pediatric Emergency Department for pediatric residents: first results of a training project focusing on pediatric severe trauma.

Background: Trauma is the leading cause of death and disability in children>1 year. Severe pediatric trauma poses unique challenges compared with adults. In Italy, pediatric trauma training is not standardized on a national level and ATLS certification is often not mandatory.

In order to help pediatric residents improve their skills in the management of severe trauma we started an in situ simulation (ISS) program in the pediatric emergency department (PED). ISS has been increasingly used to consolidate clinical knowledge, technical and non-technical skills. Furthermore ISS allows the identification of specific latent safety threats (LSTs) preventing potential harm to patients.

Limited data are available on the use of ISS as a tool for pediatric residents training in severe trauma and for identification of trauma related PED LSTs.

Objective: to describe our ISS project focusing on i) Residents’ satisfaction; ii) Identification of PED LSTs.

Methods: We ran 11 ISS (Jan 2016-Jan 2017) on pediatric severe trauma case scenarios at the PED of a tertiary care academic hospital. All trainees were asked to complete a structured feedback form at the end of each simulation. Simulation staff systematically collected data on LSTs identified

Results: A total of 32 trainees (54% of the eligible population) actively participated to 11 ISS (41% previously participated in simulation courses, none ATLS certified).

i)Trainees satisfaction with pediatric trauma ISS was overall high (9/10). On a score from 0 to 10 the perceived efficacy in reducing the anxiety level on the management of severe trauma was rated as 7.5; the perceived efficacy in understanding communication problems and improving communication skills were rated respectively 9.0 and 8.1; the efficacy of debriefing in highlighting relevant clinical knowledge gaps in trauma management and in raising awareness on the importance of non-technical skills in trauma management were rated as 8.1 and 9.3 respectively. Perceived usefulness of ISS as an effective training tool was very high,9.7.

ii)Four main LSTs were identified: 1) Long time to calculate drugs dilutions and their non- standardized preparation; 2) Small multi-parameter monitor; 3) Delayed or missed activation of key consulting physicians for trauma management; 4) Not readily available hypertonic saline. All were addressed.

Conclusions: Pediatric residents were highly satisfied with the ISS project on severe pediatric trauma, and considered ISS an effective tool to raise awareness on knowledge gaps and non-technical skills. ISS on trauma identified relevant LSTs that were addressed in conjunction with the patient safety committee to ensure optimal care.


Marco DAVERIO, Francesco MARTINOLLI (PADOVA, Italy), Valentina STRITONI, Daniele DONÀ, Emiliana CAMPAGNANO, Liviana DA DALT, Silvia BRESSAN
08:30 - 17:40 #11266 - In the world of terrorism - think sarcoidosis.
In the world of terrorism - think sarcoidosis.

Diagnosing patients with sarcoidosis in the emergency department can be rather challenging, especially when they present with atypical symptoms as it happens most of the times. Our young, male, previously healthy patient presented with atypical joint pain, tiredness, atypical neurological symptoms such as decreased power in the lower legs, sensitivity abnormalities, lower back pain and intermittent blurred vision. He has been investigated for over 2 month by rheumatology, cardiology and neurology without any results or diagnosis. On examination the only notable signs were the bilateral red, hot, swollen ankles. Laboratory results have also been highly atypical/unremarkable with an increase in CRP only.

This patient not only has presented with atypical features of the disease but didn’t match any of the racial or ethnographic high risk groups, being a white male patient. However, he was working in a stressful environment in a big city, being exposed to exogenous antigen triggers and a lot of stress.

A targeted chest X-ray, a CT thorax can easily help in the diagnosis of this disease which later on can be confirmed by a bronchoscopy. 

Evidence shows that the number of sarcoidosis cases has increased by a 4-fold after the 9/11 terror attack in the US in a certain group of patients such as healthcare workers, fire fighters and teachers. Knowing that this disease is highly impacted by stressful environment, exogenous antigens etc., we should be considering this diagnosis sooner rather than later in the emergency department.

Taking in consideration the current European situation and terror attacks/threats, after the attack in Paris, the airport and the subway attacks in Brussels as well as different attempt in other European countries (Germany, Sweden, UK), we may also expect an increased number of the incidence of sarcoidosis in our European countries.

Patients presenting with atypical symptoms and coming from a stressful environment must be considered for sarcoidosis and appropriate investigations should be requested.


Ibolya TOTH (ZOTTEGEM, Belgium), Said PROF. HACHIMI IDRISSI
08:30 - 17:40 #11831 - In-hospital cardiac arrest: Impact of ERC 2010 and 2015.
In-hospital cardiac arrest: Impact of ERC 2010 and 2015.

Introduction

Sudden cardiac arrest is one of the leading causes of death in Europe. European Resuscitation Council Guidelines of Resuscitation 2015 emphasise the importance of early recognition of detoriating patient and prevention of cardiac arrest – once cardiac arrest occurs, only ~20% of patients will survive to go home (ERC 2015).

The aim of this study was to evaluate efficiency of the reform of in-hospital resuscitation system in North Estonia Medical Centre started in 2009.

Methods

The authors of this study used data collected from hospital database and a special resuscitation forms filled by ALS team leaders in case of every in-hospital resuscitation attempt. The retrospective analysis of data was performed to compare efficiency of resuscitation attempts in the years 2008 and 2015-2016. The primary outcome measure was survival to hospital discharge. The authors also reported secondary outcomes such as return of spontaneous circulation (ROSC), ALS start time, and the first defibrillation time in patients with shockable rhythm.

Results

There were performed 84 in-hospital resuscitation attempts in 2008 and 256 in 2015-2016. The survival to hospital discharge was significantly better in the years 2015-2016: 21.4% (18 pts) in 2008 vs. 42.8% (110 pts) in 2015-2016 (p<0.01). There was not found statistical difference in ROSC between two groups: 57.1% (48 pts) in 2008 and 67.3% (173 pts). No significant changes indentified in timing of ALS start and the first defibrillation in patients with shockable rhythm.

Authors also compared the same outcomes in 2008 and 2015-2016 in general wards (GW) and in the intensive care units and emergency department (ICU&ED). The survival to hospital discharge was significantly better in the years 2015-2016 in ICU&ED group: 23.4% (15/64 pts) in 2008 vs. 50.5% (92/182 pts) in 2015-2016 (p<0.001). Similar results were reported regarding ROSC. ROSC was statistically better in ICU&ED patients in 2015-2016: 57.8% (37/64 pts) in 2008 vs. 75.3% (137/182 pts) in 2015-2016 (p<0.01). No significant differences found in survival to hospital discharge either ROSC between 2008 and 2015-2016 in GW. ALS start and the first defibrillation time were significantly better in ICU&ED group as in 2008 as in 2015-2016. 

Conclusion

The novel in-hospital resuscitation system based on ERC Guidelines 2010 and 2015 mostly influenced on resuscitation attempts results in the ICU and ED, but there was very little progress in the resuscitation in general wards. In order to succeed, the logistics of response to IHCA in general wards needs to be reassessed and there should be more resuscitation trainings (including VF/VT recognition and defibrillation techniques training).


Dr Arkadi POPOV (Tallinn, Estonia), Kaisa JOARAND
08:30 - 17:40 #10717 - Incarcerated Spiegel's Hernia.
Incarcerated Spiegel's Hernia.

Clinical case

A 50-year-old man with a personal history of hypertension and diabetes mellitus, surgically operated on abdominal hernia, right inguinal hernia, and gastric bypass.

He went to the emergency room because of intense abdominal pain, 3 days of evolution, which increased with cough and sensation of mass in the right hypochondrium. The previous day also comes and is discharged from home after symptoms improve. Afebril at all times. No nausea or vomiting. No alteration of the intestinal habit. No other associated symptoms.

Exploration

Stably hemodynamically.

In the exploration, it emphasizes patient's prostration through pain, a globulous abdomen that makes it difficult to explore with a moderate mass sensation or herniation in the right hypochondrium with pain on the surface palpation but without signs of peritoneal irritation. Signs of Blumberg and Murphy Negative

Supplementary tests

Blood chemistry: Hemoglobin: 12.1 mg / dl, Leukocytes: 15100 (Neutrophils: 80%, Lymphocytes: 12%), Normal clotting, Biochemistry with hepatic-pancreatic profile without alterations except Protein C Reactive: 31.

Radiography of the abdomen: without alterations

Evolution

In spite of the medication the patient remains with much pain and abdominal CT is requested where Spiegel's right hernia with 6.5 cm x 6.5 cm orifice with mesenteric fat and small intestine loops inside, discrete increase of the attenuation Of the fat inside the hernia sac without free fluid, moderate distension of some small intestine loops on the left flank proximal to the hernia.

Given the results, an evaluation by General Surgery is requested for emergency surgical intervention in view of the persistence of pain and later association of nausea and vomiting.

JC: Incarcerated abdominal wall spiegel hernia


Carolina GARRIDO CANNING, Rafael INFANTES RAMOS (Málaga, Spain), Jose Ignacio VALERO ROLDAN, Maria Eugenia REYES GARCIA, Ivan VILLAR MENA, Cristina FERNANDEZ- FIGARES MONTES
08:30 - 17:40 #11143 - Incidence and risk factors of long-term opioid use in elderly trauma patients.
Incidence and risk factors of long-term opioid use in elderly trauma patients.

Objective: To evaluate the incidence and risk factors of 1-year post-injury opioid use in elderly trauma patients.

Background: The current epidemic of prescription opioid misuse and overdose observed in North America is generally associated with young patients. However, little is known on long-term opioid use among the elderly trauma population.

Methods: In a retrospective observational multicenter cohort study conducted on registry data, we included all patients 65 years and older admitted (hospital stay>2 days) for injury in 57 adult trauma centers in the province of Quebec (Canada) between 2004 and 2014. We searched for filled opioid prescriptions in the year preceding the trauma, within 3 months after, and 1 year following the trauma.

Results: A total of 39,833 patients were selected for analysis. Mean age was 79.3 years (±7.7) and 69% were women. 87% of the sample was opioid naïve. After the injury, 38% of the patients filled an opioid prescription within the 3 months and 10.9% (95%CI: 10.6%-11.2%) filled an opioid prescription 1-year post-trauma: 6.8% (95%CI: 6.5%-7.1%) for opioid naïve and 37.6% (95%CI: 36.3%-38.9%) for opioid non-naïve patients.Controlling for confounders, patients who filled 2 or more opioid prescriptions before the injury and those who filled an opioid prescription within 3 months after the trauma were 11.5 and 3 times more likely to use opioid 1 year after the trauma, respectively.

Conclusions: These results highlight that elderly trauma patients are at risk of long-term opioid use, especially if they had pre-injury or early post-injury opioid consumption.


Raoul DAOUST, Jean PAQUET, Lynne MOORE, Marcel EMOND, Judy MORRIS (Montréal, Canada), Sophie GOSSELIN, Gilles LAVIGNE, Manon CHOINIÈRE, Aline BOULANGER, Celine GELINAS, Dominique ROULEAU, Melanie BERUBE, Jean-Marc CHAUNY
08:30 - 17:40 #11544 - Incidence of patients diagnosed with CVA in Emergency Department.
Incidence of patients diagnosed with CVA in Emergency Department.


Sântimbreanu GEORGE-MIRCEA, Ruian RALUCA (, Romania), Moga ELISABETA
08:30 - 17:40 #11758 - Infant botulism in Italy: antidote treatment consideration from 8 years experience.
Infant botulism in Italy: antidote treatment consideration from 8 years experience.

Objective. Infant botulism (IB) results from absorption of neurotoxins produced in situ by Clostridia colonizing the intestinal lumen in infants less than one-year. To date, IB remains an underdiagnosed disease due to insidious clinical onset and despite the typical “floppy-baby” picture. Severe IB cases may require specific treatment, but antidote type varies in several countries (even if specific neutralizing capability is comparable) and the appropriate dose is not jet internationally standardized. For US-BAT (heptavalent) formulation, a paediatric dosage is proposed. In Italy and EU, a 500 ml standard dose of Trivalent-Equine-Antitoxin (750 IU-anti-A, 500-anti-B, 50-anti-E/ml) (TEA) is indicated for all the botulism forms. The optimal dose should be related with the circulating toxins levels, that in IB is known to be low, so TEA require a dose adjustment in IB. Methods. All laboratory-confirmed and treated IB cases collected from 2009 to date were evaluated concerning demographics, clinical manifestations, toxin-type, antitoxin administered dose, adverse reactions, outcome. Case series: Thirteen cases of IB were collected (mean age 16±7.59 weeks, body-weight from 679 to 3.744 g). History for honey ingestion was positive in 3 cases: no other definitive sources of spores have been identified. Constipation (starting 2-3 weeks before) was the first symptom in the majority of cases. Due to rapid progressive worsening of neurological symptoms, 9 patients (69%) were treated with TEA: 6/9 were breastfed. The administered dose was progressively reduced during the years from 40 ml/kg to 10 ml/kg. Nor acute or delayed adverse reactions were registered. After TEA administration clostridiocidal antibiotic therapy and whole bowel irrigation were started. Main clinical manifestations were severe hypotonia (7/9;77.7%), dysphagia (6/9;66.6%), difficult suction (6/9;66.6%), mydriasis (6/9;66.6%), stypsis (6/9;66.6%) and ptosis (5/9;55.5%). Four patients had a “surgical abdomen” (only in 1 explorative laparotomy was needed). Four babies required intubation and respiratory support. All patients fully recovered (length of hospital stay ranged from 15 to 57 days). Clostridium botulinum type-A (1 case), type-B (5 cases), type Bf (1 case) and Clostridium butyricum type-E (2 case) were isolated from stool samples. In one case type-B toxin was detected in blood (4.000 minimal lethal dose). Conclusion: Equine-Antitoxin is safely used to treat IB in several countries. The optimal-dose of TEA remains a challenge: 10 ml/kg resulted safe and effective to counteract the circulating toxin in cases of Italian IB. This dose is bigger than those used in Argentina and US, and a further reduction can be evaluated.


Davide LONATI (PAVIA, Italy), Bruna AURICCHIO, Sarah VECCHIO, Sara DI GIULIO, Virgilio COSTANZO, Azzurra SCHICCHI, Fabrizio ANNIBALLI, Carlo Alessandro LOCATELLI
08:30 - 17:40 #11315 - Influenza planning and preparedness in the pediatric emergency department.
Influenza planning and preparedness in the pediatric emergency department.

Objectives: The Severe Acute Respiratory Syndrome epidemic (SARS) and 2009’s H1N1 influenza pandemic highlighted the need to prepare for infectious disease emergencies. The H1N1 pandemic was characterized by high pediatric incidence rates and led many experts to call for increased attention to children’s influenza preparedness. The purpose of this study was to explore pediatric emergency department (ED) leaders’ experiences preparing for and responding to surges in seasonal influenza activity.

Methods: Purposeful sampling was used to recruit ED medical directors from pediatric hospitals across English-speaking Canada. Recruitment occurred from January 2016 to April 2016 (n=12). Data was collected through in-depth individual interviews. A grounded theory approach was used to identify common themes from participant responses.

Results: Four themes characterized respondents’ experiences with seasonal influenza: (i) care for children with suspected influenza needs to be considered in the broader context of peak season viral respiratory pathogen preparedness; (ii) EDs have varied states of preparedness and abilities to respond to seasonal influenza surges; (iii) ED’s that maintain strong relationships with public health and community agencies find these collaborations to be beneficial in responding to seasonal influenza surges; and (iv) Knowledge translation to ED leaders, primary care providers and to the public is essential, but can be challenging when there is no universally accepted health systems approach to managing children with suspected influenza.

Conclusions: Pediatric ED leaders report varied states of preparedness and abilities to respond to surges in seasonal influenza activity. Much work remains to address preparedness gaps. Knowledge translation amongst ED leaders, primary care providers and the public should be a key target for future research and clinical interventions. 


Weingarten LAURA E. (Hamilton, Canada), Dawson EMILY C., Franc JEFFREY, Moore KIERAN
08:30 - 17:40 #11970 - Ingested cover screw driver during a dental procedure.
Ingested cover screw driver during a dental procedure.

A 65 year-old-man was admitted to our emergency department after the ingestion of a cover screw driver during a dental procedure. A plain abdominal x-ray revealed the ingested foreign body. As he had no active symptoms, an emergency colonoscopy was not planned, and he was discharged with the recommendation of visual self-inspection of stools and returning for a control physical examination. Three days later, the patient had still no complaints. A control x-ray showed that the cover screw driver was now at the level of caecum. The patient was discharged with no additional intervention. The ingestion or inhalation of foreign bodies can occur during dental procedures due to patient- or physician-related factors. Emergency physicians should be aware of the management of such cases.


Cemil KAVALCI (Ankara, Turkey), Afsin Emre KAYIPMAZ, Nur ALTIPARMAK
08:30 - 17:40 #10940 - Inhaler use and duration of methoxyflurane analgesia in adult patients with acute pain due to contusions and lacerations: a sub-analysis of STOP! – a randomised, double-blind, placebo-controlled study.
Inhaler use and duration of methoxyflurane analgesia in adult patients with acute pain due to contusions and lacerations: a sub-analysis of STOP! – a randomised, double-blind, placebo-controlled study.

Background

Acute pain is a frequent complaint in the Emergency Department (ED)1 but remains widely undertreated2. The STOP! study investigated the efficacy and safety of low-dose methoxyflurane analgesia administered via a handheld inhaler (Penthrox®, 3mL dose) for treatment of acute pain in 300 patients ≥12 years presenting to the ED with non-life-threatening trauma. Reduction in pain intensity in the first 20 min of treatment has previously been reported3. We describe pain intensity beyond 20 min and patterns of inhaler use in a subgroup of adult patients with contusions (N=50), lacerations (N=7) or both (N=3).

 

Methods

Patients were randomised at triage to methoxyflurane (3mL) or placebo (normal saline), both inhaled as needed from a Penthrox® inhaler. Patients could cover the diluter hole in the mouthpiece to inhale a higher concentration of study medication if required. A second inhaler and/or rescue medication (paracetamol/opioids) were provided if requested by the patient. Pain intensity was assessed using a 0-100 visual analogue scale (VAS, PainlogTM) at 5, 10, 15, 20 and 30 min after the start of treatment, then every 30 min until discharge. Adverse events (AEs) were recorded from enrolment until discharge, and at safety follow-up (Day 14±2).

 

Results

The subgroup included 29 males, 31 females, aged 18-68. Mean VAS pain intensity continued to decrease beyond 20 minutes after the start of treatment and was consistently lower for methoxyflurane-treated patients than placebo-treated patients. In the methoxyflurane group, mean decreases of -47.2, -52.7, -52.4 and -51.0mm (from a baseline mean of 69.0mm) were observed at 20, 30, 60 and 90 min. In the placebo group, mean decreases of -9.8, -11.8 and -14.3mm (from a baseline mean of 63.5mm) were observed at 20, 30 and 60 min (data not shown for later time points where n≤1). Eight patients (26.7%) in the methoxyflurane group and 5 patients (16.7%) in the placebo group requested a second inhaler; median time between dispensing of the first and second inhalers was 67.5 min for methoxyflurane and 40.0 min for placebo. 43.3% of patients in the methoxyflurane group and 36.7% of patients in the placebo group covered the diluter hole when using the inhaler.  AEs (mostly dizziness/headache) were reported by 73.3% of patients receiving methoxyflurane and 33.3% of patients receiving placebo; most AEs were mild and transient and only one AE in the placebo group (vomiting) led to withdrawal.

 

Conclusions

The results show that the previously reported early reduction in pain intensity with low-dose methoxyflurane administered via the Penthrox® inhaler is maintained for the duration of use in adult patients with acute pain due to contusions or lacerations.

 

References

  1. Cordell et al. Am J Emerg Med 2002;20:165–169.
  2. Pierik JGJ et al. Pain Med 2015;16:970-84.
  3. Coffey F et al. Emerg Med J 2014;31:613-8.

 

Acknowledgements

Study sponsor: Medical Developments International (MDI)

®PENTHROX is a registered trademark of MDI.


Patrick DISSMANN (Detmold, Germany), Frank COFFEY, Kazim MIRZA, Mark LOMAX
08:30 - 17:40 #11151 - Initial use of supplementary oxygen for trauma patients: a systematic review.
Initial use of supplementary oxygen for trauma patients: a systematic review.

Background: Oxygen is one of the most commonly used drugs in the initial treatment of both spontaneously breathing and intubated trauma patients. However, supplementary oxygen induces a risk of hyperoxemia, which has been associated with greater mortality in non-trauma patient populations.

Objective: This systematic review aimed to identify and describe the evidence for the use of supplementary oxygen for spontaneously breathing trauma patients in the initial phase of treatment, and the use of high (0.60-0.90) vs. low (0.30-0.40) inspiratory oxygen fraction (FiO2) for intubated trauma patients in the initial hospital phase of treatment.

Methods: Medline, Embase, and The Cochrane Library were systematically searched in September 2016 for studies fulfilling the following pre-defined criteria: trauma patients (Population); supplementary oxygen (Intervention) vs. no supplementary oxygen (Control) for spontaneously breathing patients and/or high (Intervention) vs. low (Control) FiO2 for intubated patients in the initial phase of treatment (< 24 hours after admission); all-cause mortality, in-hospital mortality, in-hospital complications, days on mechanical ventilation, and/or length of stay (LOS) in hospital/intensive care unit (ICU) (Outcomes); prospective interventional trials (Study design). There was no restriction to language or publication year. Two independent reviewers screened titles, abstracts, and relevant full-texts, and extracted data from included studies using a pre-piloted form. The protocol was registered on PROSPERO (ID no. 42016050552).

Results: 6142 citations were screened with an interrater reliability (Cohen’s Kappa) for screening and selecting studies of 0.88. No prospective, interventional trials on spontaneously breathing trauma patients were identified, and only two interventional trials on intubated trauma patients fulfilled the inclusion criteria. These included a study on 21 intubated blunt chest trauma patients from years 1981-1984, where the patients received a FiO2 of 0.45 (intervention group, n=11) or 0.60 (control group, n=10) during the first 48 hours of hospital admission. The study found no difference in days on mechanical ventilation, however, two patients in the control group died compared to none in the intervention group. In the other trial from 2014, 68 trauma patients with severe traumatic brain injury were randomized to receive a FiO2 of 0.80 (intervention group, n=34) or 0.60 (control group, n=34) during mechanical ventilation for the first six hours after the incident. There was no significant difference in the hospital or ICU LOS between the two groups.

Conclusions: Evidence for the use of supplementary oxygen for spontaneously breathing trauma patients is lacking, and evidence for low vs. high FiO2 for intubated trauma patients is limited. High-quality, prospective, interventional studies on the use of supplementary oxygen in the initial phase of treatment of trauma patients are urgently warranted.

 


Trine Grodum ESKESEN (Copenhagen Ø, Denmark), Josefine Stokholm BAEKGAARD, Jacob STEINMETZ, Lars S. RASMUSSEN
08:30 - 17:40 #11373 - Initially Cauda Equina, Finally Aortic Thrombosis.
Initially Cauda Equina, Finally Aortic Thrombosis.

Background:

Low back pain is a frequent cause of ED visit,  among patients who present with back pain to ED, less than 1 percent will have a serious underling cause. An aortic saddle thrombosis causing cauda equine syndrome followed by paraplegia is an extremely rare phenomenon.

Background:

Low back pain is a frequent cause of ED visit,  among patients who present with back pain to ED, less than 1 percent will have a serious underling cause. An aortic saddle thrombosis causing cauda equine syndrome followed by paraplegia is an extremely rare phenomenon.

Power was as follow: right hip flexion 4/5, knee 3/5, ankle dorsiflexion and extensor hallucis longus (EHL) measuring 3/5.

Sensation was noted to be decreased on L4-L5 and S1 dermatomes.

The lower extremities were warm, dorsalis pedis pulses were noted to be present bilaterally and no discoloration of the limbs.

MRI showed multiple lumber disks, however, Cauda Equina was normal and MRI result could not  explain his findings.

His labs were normal except for high WBC( 18000), and slightly elevation in creatinine.

Patient admitted for observation and pain management, he had on and off severe back pain, but in between he was able to stand and walk, no bowl or bladder dysfunction, and pain was controllable.

After 24 hrs, patient developed sudden onset of paraplegia, bilateral lower limbs ischemia, dorsalis pedis became absent both sides .

ECG revealed ST elevation MI and CT angiography showed aortic saddle thrombosis, for that he underwent surgery immediately.

His EF was very low on Echocardiography, the last was repeated three days after showing the same findings plus thrombus left ventricle.

Unfortunately, patient died five days after surgery.

Discussion:

The cauda equina is supplied by greater radicular artery which originates in vast majority of people from the intercostal arteries at the level of T7–T12 or at the level of T8–L4.

Very rarely it originates at the level of L3 (1.4%) or L4–L5 (0.2%), if patient had thrombosis in such low origin, then the picture will be cauda equina like syndrome as in this patient here.

Recent studies demonstrate that patients presented with thrombosis (40%) have a potential hypercoagulable, which might explained why our patient had saddle thrombosis, STEMI, and left ventricle thrombus.

In addotion, 50% of cases have no peripheral vascular symptoms or delayed symptoms making diagnosis of saddle embolism difficult in the early stages.

Conclusion:

In patients presenting with cauda equina without radiological findings, this should raise a high suspicion for vascular etiologies.

Finally, acute aortic occlusion is a serious event and may present with paraplegia, this needs early recognition and treatment.

                    


Tarek ALREFAI (Doha, Qatar), Helmy GOUDA, Mahmoud SAQR, Abdulla ALSOUKI
08:30 - 17:40 #11374 - Initially Cauda Equina, Finally Aortic Thrombosis.
Initially Cauda Equina, Finally Aortic Thrombosis.

Background:

Low back pain is a frequent cause of ED visit,  among patients who present with back pain to ED, less than 1 percent will have a serious underling cause. An aortic saddle thrombosis causing cauda equine syndrome followed by paraplegia is an extremely rare phenomenon.

Patient:

 A 48 years old male, he is alcoholic and heavy smoker,  presented to emergency department (ED) with a complaint of the sudden onset of low back pain after lifting heavy object, radiated to right leg. straining at micturition, weakness, numbness and change of sensation  right lower limb, all started 12 hours before attending to ED.

On presentation patient rated his pain 9/10, his initial vital sings were noted to be:

BP: 160/90, HR: 100 bpm, RR: 19/min, T: 36.9  and saturation 98% in room air.

Examination:

Power was as follow: right hip flexion 4/5, knee 3/5, ankle dorsiflexion and extensor hallucis longus (EHL) measuring 3/5.

Sensation was noted to be decreased on L4-L5 and S1 dermatomes.

The lower extremities were warm, dorsalis pedis pulses were noted to be present bilaterally and no discoloration of the limbs.

MRI showed multiple lumber disks, however, Cauda Equina was normal and MRI result could not  explain his findings.

His labs were normal except for high WBC( 18000), and slightly elevation in creatinine.

Patient admitted for observation and pain management, he had on and off severe back pain, but in between he was able to stand and walk, no bowl or bladder dysfunction, and pain was controllable.

After 24 hrs, patient developed sudden onset of paraplegia, bilateral lower limbs ischemia, dorsalis pedis became absent both sides .

ECG revealed ST elevation MI and CT angiography showed aortic saddle thrombosis, for that he underwent surgery immediately.

His EF was very low on Echocardiography, the last was repeated three days after showing the same findings plus thrombus left ventricle.

Unfortunately, patient died five days after surgery.

Discussion:

The cauda equina is supplied by greater radicular artery which originates in vast majority of people from the intercostal arteries at the level of T7–T12 or at the level of T8–L4.

Very rarely it originates at the level of L3 (1.4%) or L4–L5 (0.2%), if patient had thrombosis in such low origin, then the picture will be cauda equina like syndrome as in this patient here.

Recent studies demonstrate that patients presented with thrombosis (40%) have a potential hypercoagulable, which might explained why our patient had saddle thrombosis, STEMI, and left ventricle thrombus.

In addotion, 50% of cases have no peripheral vascular symptoms or delayed symptoms making diagnosis of saddle embolism difficult in the early stages.

Conclusion:

 In patients presenting with cauda equina without radiological findings, this should raise a high suspicion for vascular etiologies.

Finally, acute aortic occlusion is a serious event and may present with paraplegia, this needs early recognition and treatment.

  


Tarek ALREFAI (Doha, Qatar), Helmy GOUDA, Abdulla ALSOUKI, Mahmoud SAQR
08:30 - 17:40 #11347 - Initially Cauda Equina, Finally Aortic Thrombosis.
Initially Cauda Equina, Finally Aortic Thrombosis.

Background:

Low back pain is a frequent cause of ED visit,  among patients who present with back pain to ED, less than 1 percent will have a serious underling cause. An aortic saddle thrombosis causing cauda equine syndrome followed by paraplegia is an extremely rare phenomenon.

Patients & Methods :

 A 48 years old male, he is alcoholic and heavy smoker,  presented to emergency department (ED) with a complaint of the sudden onset of low back pain after lifting heavy object, radiated to right leg. straining at micturition, weakness, numbness and change of sensation  right lower limb, all started 12 hours before attending to ED.

On presentation patient rated his pain 9/10, his initial vital sings were noted to be:

BP: 160/90, HR: 100 bpm, RR: 19/min, T: 36.9  and saturation 98% in room air.

Systemic review was unremarkable.

Examination:

Power was as follow: right hip flexion 4/5, knee 3/5, ankle dorsiflexion and extensor hallucis longus (EHL) measuring 3/5.

Sensation was noted to be decreased on L4-L5 and S1 dermatomes.

The lower extremities were warm, dorsalis pedis pulses were noted to be present bilaterally and no discoloration of the limbs.

MRI showed multiple lumber disks, however, Cauda Equina was normal and MRI result could not  explain his findings.

His labs were normal except for high WBC( 18000), and slightly elevation in creatinine.

Patient admitted for observation and pain management, he had on and off severe back pain, but in between he was able to stand and walk, no bowl or bladder dysfunction, and pain was controllable.

After 24 hrs, patient developed sudden onset of paraplegia, bilateral lower limbs ischemia, dorsalis pedis became absent both sides .

ECG revealed ST elevation MI and CT angiography showed aortic saddle thrombosis, for that he underwent surgery immediately.

His EF was very low on Echocardiography, the last was repeated three days after showing the same findings plus thrombus left ventricle.

Unfortunately, patient died five days after surgery.

Discussion :

The cauda equina is supplied by greater radicular artery which originates in vast majority of people from the intercostal arteries at the level of T7–T12 or at the level of T8–L4.

Very rarely it originates at the level of L3 (1.4%) or L4–L5 (0.2%), if patient had thrombosis in such low origin, then the picture will be cauda equina like syndrome as in this patient here.

Recent studies demonstrate that patients presented with thrombosis (40%) have a potential hypercoagulable, which might explained why our patient had saddle thrombosis, STEMI, and left ventricle thrombus.

In addotion, 50% of cases have no peripheral vascular symptoms or delayed symptoms making diagnosis of saddle embolism difficult in the early stages.

Conclusion:

 In patients presenting with cauda equina wihout radiological findings, this should raise a high suspicion for vascular etiologies.

Finally, acute aortic occlusion is a serious event and may present with paraplegia, this needs early recognition and treatment.

  

                     


Tarek ALREFAI (Doha, Qatar), Abdulla ALSOUKI, Mahmoud SAQR, Helmy GOUDA
08:30 - 17:40 #11551 - Innovative problem solving: finding creative solutions to the ED’s most complex challenges.
Innovative problem solving: finding creative solutions to the ED’s most complex challenges.

For many years, operations improvement experts in healthcare have embraced a multitude of different “tools” as strategies for solving some of the most complex operational and experiential challenges facing the ED.  The challenge with every tool is that it is none of them are one-size-fits-all and each have their strengths and their limitations.  This session will introduce the concept of using a philosophy of design thinking as a framework to approach developing solutions in ED operations, workforce planning, technology planning, facility design and the patient experience.  Multiple case studies will be presented to illustrate how design thinking and interdisciplinary workgroups can be leveraged to achieve transformative solutions better, faster and cheaper than through the use of traditional process improvement tools.


Manuel HERNANDEZ (Chicago, USA)
08:30 - 17:40 #11225 - Input of MEDITEC software for maintenance of medical record in emergency call center.
Input of MEDITEC software for maintenance of medical record in emergency call center.

Background:

Each Medical Record shall contain sufficient, accurate information to identify the patient, support the diagnosis, justify the treatment, document the course and results, and promote continuity of care among health care providers. Several studies have evaluated the maintenance of medical record in order to improve quality.In emergency call center, maintenance of medical record by paramedic and emergency doctor is more difficult due to requirement of rapidity and accuracy. In order to improve the traceability of medical record of each call, a software (MEDITEC) has been created and used since 2016.

The aim of this study is to check if there are benefits of using software compared to paper form of medical record in our emergency call center in term of traceability.

Methods :

It was a descriptive comparative study performed in the emergency call center of our university hospital. Maintenance of medical record was evaluated during a period of 7 days in respectively paper form and electronic medical record. Every item of the record was checked. Data collection was performed using grid established according to French referential of emergency call centers. A compliance rate (CR) was calculated for each item to evaluate his filling.

Results :

Administrative data filling was significantly improved by using MEDITEC Software : the CR was 0.84 compared to 0.65 in paper filling, and it concern mainly the identity of the caller and the patient. Traceability of medical decision and diagnosis in medical center was also improved (CR changed from 0.81 to 0.95).However, the recorder of time delays for medical intervention was relatively poor in the two forms of medical record. Outcome and clinical situation's evolution was also poorly filled in electronic record (CR=0.25)

Discussion :

Medic software improved significantly administrative and clinical data filled by paramedic and doctors in our emergency call center. This result is similar to other several studies. However traceability of intervention times still insufficient.

We must improve filling of our electronic record for reasons of efficiency and to promote continuity of care from extra hospital intervention to department of care especially for patient suffering from critical disease.  In order to improve the traceability of medical record of each call and to a achieve adequate level of quality, we must develop technical means and plan local good practice' report for our staff. 


Majdi OMRI, Hajer KRAIEM (Sousse, Tunisia), Rabeb MBAREK, Sawssen ALOUANE, Sami BEN AHMED, Mohamed Aymen JAOUADI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11573 - Insights into frequency, peak incidence and relevance of alarms at a dutch emergency department.
Insights into frequency, peak incidence and relevance of alarms at a dutch emergency department.

Introduction: Monitoring at the emergency department (ED) is used to see changes in vital parameters or to observe cardiac rhythm. A feeling of safety and sometimes convenience may be alternative motivations for nursing and medical staff. Frequent alarms are known to lead to alarm fatigue and loss of concentration, a risk in the ED. In this descriptive, prospective study, alarm frequency, relevance, time to response and peak times are investigated. An expert panel of emergency physicians will review indications for monitoring based on initial patient presentation. Results will provide insights in possibilities to better focus monitoring to reduce alarm fatigue and concentration loss whilst still detecting relevant vitals.

Methods: Prospective analysis of alarm frequency and response times using Philips monitoring database of 2 weeks of all 14 Urgent Care beds at ED OLVG in Amsterdam. Alarm relevance is combined with expert panel judgment of monitoring indication based on initial patient presentation.

Results: Total alarms of x in 14 days, average of x per day. An average of x false positive alarms is seen per day. Peak times are during breaks and shift handover, when x% of alarms are false positive. Average response time was x seconds for urgent and x sec for non-urgent alarms, with longer response time during breaks and handover. According to the expert panel, x% of patients with alarms were monitored unnecessarily. This corresponds with x hours of alarms per day.

Conclusion: Reduction of alarms is possible, specifically during breaks and handover moments. An implementation study is required to ascertain adequate monitoring of vitals, and to address the issues of sense of safety and convenience for staff.


Ursula ROLF (Amsterdam, The Netherlands), M.m.s. ZWARTSENBURG
08:30 - 17:40 #11165 - Instant Messaging Mobile Application Used in Emergency Room: Review Study in One Regional Hospital of Taiwan.
Instant Messaging Mobile Application Used in Emergency Room: Review Study in One Regional Hospital of Taiwan.

Background: We live in the smartphone-occupied world now. With popularity of wireless service and higher transmitting rate people can deliver image messages by web-based instant messaging (IM) application such as Line, WeChat, WhatsApp and Snapchat which are most popular in different countries separately in recent years. In this study, we try to find out the issues of radiological images transmission such as the change of judged accuracy or associated legal problems.

  Methods: The images of patients present at our trauma center are collected from Oct. 2014 to Dec. 2014 if we are in doubt about the radiological finding. There are 90 patients with 121 pieces of doubted images are included. 80 pieces are radiograph and 41 pieces are computer tomography(CT) photo. One emergency physician photoed the doubted radiological images on the monitor of emergency room by smartphone and transmitted these photos to our radiologist by the memory disc. The radiologist reviewed these doubted finding again. In this study the photo quality, existence of Moire pattern and judged results of transmitted photos are compared with the original ones. The chi-squared test is used for statistics analysis.  

  Results: In doubted radiographs we find our major problems are fracture or dislocation which are 71.3%. If no Moire pattern is found on transmitted photos 57.6% of transmitted photos are under good imaging quality. The existence of Moire pattern is related to transmitted photo quality and there is significance in statistics. There are 70.8% of transmitted photos having no Moire pattern noted. We find the Moire pattern and quality-changing of transmitted photos could not have the influence in the judgement- accuracy of transmitted ones. We can’t find the significance in statistics. The judged accuracy of these photos is 73.6 %

  Discussion: The transmission of instant messaging application will not change the results of transmitted images at limb fracture or others major problem such as subdural hematoma or intracerebral hemorrhage even through the transmitted quality is not satisfactory. How can we avoid violating the provisions when we need the transmitting function of instant messaging mobile application. In Taiwan the Personal Data Protection Act amended on Dec. 2015 should be obeyed. When we deliver the radiological images the consent of patients should be gathered. Besides we have to make sure that this procedure could promote the benefit of our patients. If the radiological image transmission is allowable we think the usage of instant messaging mobile application will improve the efficiency of consultation in one regional hospital.


Chia-Hsi CHEN (Chiayi, Taiwan, Taiwan), Tak-Yee WONG, Jui-Fang HUANG, Su-Lan WU
08:30 - 17:40 #11572 - Integration of Radiological Findings and a Clinical Score in the Diagnostic Evaluation of Pediatric Appendicitis.
Integration of Radiological Findings and a Clinical Score in the Diagnostic Evaluation of Pediatric Appendicitis.

Background & Aim:

Acute appendicitis is the most common acute abdominal emergency requiring surgical intervention in the pediatric age group. We aimed to determine the value of ultrasonography (US) and abdominal radiography for appendicitis in children when combined with clinical assessment based on the Pediatric Appendicitis Score (PAS). We also aimed to establish a practical pathway for acute appendicitis in childhood.

Methods:

Prospective, observational cohort study conducted at an urban, academic pediatric emergency department. Patients were determined to be at low (PAS 1–4), intermediate (PAS 5–7), or high (PAS 8–10) risk for appendicitis. Low-risk patients were discharged, Intermediate-risk patients for appendicitis underwent plain radiography and US. High-risk patients received immediate surgical consultation.

Results:

A total of 288 children with a mean age 11.1 (SD ±3,63 ) years. Surgery was performed in 134 (46.5%) patients, and 128 (95.5%) had positive histopathology. PAS of 1–4 was noted in 66 (22.8%), 4–7 in 139 (48.3%), and 8–10 in 83 (28.8%) patients. The missed cases were 6 of 288 (2%), and negative appendectomy rate was 6 of 134 (4.4%). When the score cut-off value was set at 6, the sensitivity and the specificity was 86.7% and 63.1%. The diagnostic performance of day-time US included a sensitivity of 91.1%, specificity 71.1%. Integrating the results of US with PAS (≥6) showed a sensitivity and specificity respectively 79.3% and 75.4%. Also, positive US findings or PAS is greater than 6 or both showed sensitivity and specificity 96.7% and 59.9%.

Discussion

Studies assessing the combination of PAS and US are rare. In a literature, sensitivity and specificity of PAS had not increased with combining US when combined assessment of PAS and US. If there is a positive US finding or PAS is greater than 6 or both, the sensitivity is increased in our study. As a conclusion, integrating the results of US and radiography with clinical assessment didn’t increase diagnostic value for acute appendicitis.


Derya AYDIN, Caner TURAN (ISTANBUL, Turkey), Ali YURTSEVEN, Petek BAYINDIR, Bade TOKER, Zafer DOKUMCU, Murat SEZAK, Eylem Ulas SAZ
08:30 - 17:40 #10866 - Intense right intercostal pain in a 47-year-old male, presenting segmental pulmonary thromboembolism.
Intense right intercostal pain in a 47-year-old male, presenting segmental pulmonary thromboembolism.

Clinic history


47 year old male without drug allergies. No toxic habits. Peronal history of cervical and lumbar disc hernias.
He went to the emergency department for painful pain at the finger tip in the right costal region of several days of evolution that has progressively increased. No dyspnea or febrile syndrome.
The patient attributes it to overexertion during work.


Physical exploration
Regular general condition, eupneic, afebrile. Basal saturation 98%. Blood pressure 130/75, Heart rate 85.
Pain scale (EVA 8).
Head and neck: no oropharyngeal anomalies, no lymphadenopathy, palpable and symmetrical carotid pulses.
Cardiopulmonary auscultation: rhythmic without murmurs, unfolding crackles to right predominance midfields with right basal hypofonesis. Tolerates conversation. No use of accessory musculature, l
Pain on intense palpation in intercostal muscles at 8º and 10º right. Limitation of exploration for patient pain.
Abdomen: soft and depressible without masses or megalias, negative blumberg, negative Murphy.
Lower limbs: no edema, no signs of deep venous thrombosis, preserved pulses.


Supplementary tests


- Blood analysis: Hb 14.7 Platelets 198,000 Leukocytes 9,200 (70% neutrophils) TP 107% glucose 134 Urea 40 Creatinine 0.86 (glomerular filtration <90) sodium 137, potassium 3.90, chlorine 103, creatine kinase 249, Lactate dehydrogenase 246, GOT 20, GPT 19, GGT 26, FA 64, total bilirubin 0.40, lactic acid 1.5, C-reactive protein 3.5. Venous gasometry (pH 7.39 PCO2 43.5 PO2 58.2).

- Chest x-ray: increased cardiothoracic index, clamping of both predominantly right costophrenic sinuses

- EKG: Sinus rhythm at 100 beats / minute without repolarization alterations


After intravenous analgesic medication, partial improvement of pain. During the stay in the polyclinic area, the patient presented a pre-clinical picture, and the patient was admitted for observation.


Good evolution during admission being asymptomatic and stable hemodynamically. Chest x-ray is repeated, persisting clamping of both predominantly right costophrenic sinuses, thus analytical extension with Dimero D with a value of 6129ng / mL.


Angiography is performed by axial tomography that reports a defect of repletion at the level of the distal branch in the right lower lobe (segment of the lower right lobe segment) compatible with pulmonary thromboembolism. Right pleural effusion of small amount.

Clinical judgment: segmental pulmonary thromboembolism of the right lower lobe. PESII. Low risk

The patient enters Pneumology


Conclusion: In the emergency department when we think of pulmonary thromboemboism, we are rapidly dealing with a sudden episode of dyspnea. We should not forget that dyspnea is only a symptom and that there are other equally frequent forms of presentation that begin with pleuritic pain, syncopal / Palpitations or anginal pain.


Manuel AGUILAR CASAS, Rafael INFANTES RAMOS (Málaga, Spain), Juan Antonio FERNÁNDEZ CEJAS, David NUÑEZ CASTILLO, Ivan VILLAR MENA
08:30 - 17:40 #11303 - Interest of pre-hospital transcutaneous cardiac pacing in acute chloroquine poisoning.
Interest of pre-hospital transcutaneous cardiac pacing in acute chloroquine poisoning.

Introduction: transcutaneous cardiac pacing allows non-invasive, safe and rapid ventricular stimulation, although there is controversy over the observed results. We report the case of severe bradyarrhythmia requiring the use of transcutaneous stimulation by the SMUR team.

Observation: this was a 40-year-old woman with a history of atrial fibrillation under amiodarone and scleroderma under chloroquine. She was management in a peripheral emergency by the SMUR team for consciousness disorders and cardiogenic shock. Upon arrival of the SMUR, the initial examination revealed a deep coma with a GCS=3/15, an impregnable blood pressure and saturation and a bradyarrhythmia at 20/min. The intervew with the family was initially non-contributory. Resuscitation measures were undertaken immediately: respiratory and circulatory assistance by adrenaline in continuous infusion without improvement. The establishment of a transcutaneous external cardiac pacing with a frequency fixed at 70 beats/min and an intensity fixed at 50 mA, made it possible to restore a blood pressure at 100/50 mmHg. The patient was transferred to the cardiac catheterization room for electrosystolic training probe. The interview revealed an attempted suicide by ingestion of an undetermned amount of chloroquine and the patient was admitted to toxicological resuscitation service.

Conclusion: this case illustrates the efficacy of transcutaneous heart pacing in severe bradycardia during acute chloroquine intoxication. Other similar cases should be included to prove the effectiveness of this technique during our prehospital practice


Wided BAHRIA (tunisie, Tunisia), Saida ZELFANI, Hela MANAI, Syrine KESKES, Rafika BEN CHIHAOUI, Samir ABDELMOUMEN, Mounir DAGHFOUS
08:30 - 17:40 #11601 - Internal Jugular Vein ultrasound for the detection of Congestive Heart Failure in Emergency Deparment patients presenting with dyspnea.
Internal Jugular Vein ultrasound for the detection of Congestive Heart Failure in Emergency Deparment patients presenting with dyspnea.

Internal Jugular Vein ultrasound for the detection of acute congestive heart failure in the Emergency department patient presening with dyspnea


Heart failure in lieu of our aging populatioon is a growing epidemic. There is an ongoing need to develop bedside tools for rapid diagnosis. Emergency ultrasound has developed numerous methods for idenifying acute heart failure, b-lines on lung ultrasound, inferior vena cava (IVC)  respiratory change, as well as bedside echo.

  In contrast to IVC ultrasound less work has been done examining the utility of ultrasound of the internal jugular veins (IJV) for the diagnosis of acute heart failure. Ultrasound of the IJV is potentially eaisier to perform and interpret, requiring little skill and not affected by a large body habitus.

  We conducted a small prospective pilot study to examine the potential of respiratory change of the cross sectional area of the (IJV) for the identification of acute heart failure in emergency department (ED) patients. Patients were selected if if they presented with to the ED with acute dyspnea and there was no obvious or emergent diagnosis such as STEMI, sepsis, pneumothorax, pneumonia.

  All participants recieved and explanation and signed an informed consent form, our research was approved by the hospitals Helsinki commitee. Fifty nine patients were recruited from June 2015 to March 2016. Of those patients included thirty four were males and twenty-five were females, the average age was seventy.

 All patients underwent an ultrasound of the jugular veins, a probe was placed in the supraclavicular area with the patient supine at a 60 degree angle, the cross sectional area and its respiratory variation was recorded. Within a few minute interval a brain naturetic peptide level (BNP) was taken.

  BNP, a sensitive marker for ruling out CHF yet is not specific we used dyspnea and an elevatd BNP level with no other obvious diagnosis as positive for congestive heart failure. We evaluated the correlation of a change of the cross sectional area of the (IJV) with levels of BNP .

   Our results showed the change of the (IJV) area for the detection of heart failure had a specificity and sensitivity of 70% with a p value of <0.01 and a cutoff level of BNP  of 100 pg/ml.

when examining patients at the extrenes of the spectrum of BNP we found a positive trend. of the twenty-five with BNP above 300 twenty-one patients had no measurable variation of IJV area. In the twenty-seven patients with BNP under 100pg/ml sixteenhad signifigant (over 50%) IJV cross sectional area change.

 Although our sample size is small we a see a promising future for ultrasound of internal jugular veins for assisting in the rapid diagnosis of heart failure in the ED   


Batsheva TZADOK (Poriya Israel, Israel), Shay SHAPIRA, Eran TAL-OR
08:30 - 17:40 #11033 - Interpersonal violence and maxillofacial injuries: behavior in the emergency unit Hospital Carlos Van Buren Valparaiso Chile.
Interpersonal violence and maxillofacial injuries: behavior in the emergency unit Hospital Carlos Van Buren Valparaiso Chile.

INTRODUCTION

Violence is a common reason for trauma consultation in emergencies, and facial injuries from this cause have been described as frequent with more than 60% involvement of this anatomical region in relation to the total of affected regions. Facial lesions have a bio-psycho-social impact that makes it a necessary public health problem to address. One of the recommendations of the Global Report on Violence and Health (WHO, 2002) is to increase the capacity to collect data on violence and establishes that it is important to have reliable data, not only to prioritize or use them to elaborate and supervise programs, but also to sensitize the population.

OBJECTIVE

The aim of the study is to characterize the behavior of maxillofacial injuries in victims of interpersonal violence treated at the Adult Emergency Unit of the Carlos Van Buren Hospital in Valparaiso, Chile.

METHODS

An observational study of maxillofacial lesions was carried out in patients who consulted in the Adult Emergency Unit in the period from April 1, 2016 to March 31, 2017. Of the total number of patients, the patients were selected according to an interpersonal violence related cause of the injury.

RESULTS

We describe the clinical and sociodemographic characteristics of the sample with a predominance of males and below 30 years age (p <0.05). The main mechanism corresponded to fist punches, alcohol consumption mediating, with higher frequency and severity in men. The most frequent fractures were located in the middle third of the face.

CONCLUSIONS

The medical-legal implications of this type of injury make the role of the emergency specialist decisive for timely, correct and detailed diagnosis for subsequent legal actions. Reports at international level have further reported that the incidence of this type of injury has been increasing and its presentation could vary according to conditions such as age, gender, geographic region, socioeconomic stratum, etiology, type of injury And the population studied, among others.


Valentina DUARTE (Viña del Mar, Chile), Fabiola WERLINGER, Constanza VIDAL, Roberto OSBEN, Santiago RIVIELLO, Mario ARRIOLA, Raúl ACEVEDO, Oscar BADILLO, Marcelo VILLALÓN, Juan CORTÉS
08:30 - 17:40 #11652 - Intranet triage tool for decision management using routine data in hospital incidents.
Intranet triage tool for decision management using routine data in hospital incidents.

Intranet triage tool for decision management using routine data in hospital incidents.

Since incidents disasters are a rare occurrence in healthcare facilities, studies have shown that there is a lack of proper and effective hospital preparedness. Regarding the complexity of providing medical care in case of critical emergencies during a crisis or incident situation in a hospital, specific problems should be addressed.

Problems not only lay in staff education. Incident planning is not well implemented or without standardized terminology. Specific problems, like “variability of the number of immobile patients”, “elevator independent evacuation strategies” and “rapid action strategies in a time of not unified command”, are insufficiently addressed. Incident plans are papers usually placed in a shelf. The joint commission speaks of this as “paper-plan-syndrome”. As a result, emergency managers need good practical tools for creating effective action plans.

Methods

Analysing the data from evacuation drills and a big exercise in a 1000 bed hospital in Krefeld Germany, we created a tool for intranet data.

Regarding specific problems on triage it addresses factors of the distribution like the number and flow of walking and not walking patients.

Nurse practitioners could easily recognize mobility status and ongoing changes considering criteria of clinical specialities, such as orthopaedic surgery, dementia and the elderly, ophthalmology, gynaecology, paediatric patients, and categorize them in walking and not walking patients, reporting it during shift change.

Using the intranet tool, they could get a better systemic collection of this information and help creating a reliable and evaluated data.

Results

We collected and analysed data in period of 3 months.

In summary 40% of patients get not walking categorized, amounting to between 90 and 135 patients. In average not walking in Ophthalmology 25%, in Orthopaedic surgery 64%, in Visceral surgery 40%, in ENT 18% and in Neurology 28%.

Discussion/Conclusion

The literature research shows that an effective preparedness against incidents and crises to prevent disasters is only possible if the capacity to handle them becomes part of the daily organizational culture.

Using daily routine mobility data with a systematic collection, documentation and categorization in walking or not walking, through nurse practitioners, is also a tool for improving hospital preparedness and the awareness of the staff regarding evacuation procedure.


Georgios LELEDAKIS (KREFELD/Germany, Germany)
08:30 - 17:40 #11898 - Intraosseous device insertion by Nurses and Paramedics – A randomized crossover simulation study.
Intraosseous device insertion by Nurses and Paramedics – A randomized crossover simulation study.

Background: Intraosseous access is recognized as the immediate alternative to intravenous access in children during resuscitation. To date there is no data supporting the possibility that nurses can obtain intraosseous access, thus freeing the physician to perform other critical roles during resuscitation. The aim of this study was to compare the success rate of intraosseous device insertion by nurses and paramedics.

Methods: We performed a randomized cross over simulation study using 2 intraosseous devices – the EZ-IO and Pediatric Nio in a piglet bone model. Seventeen novice nurses (during emergency medicine training) and 15 active EMS paramedics were randomized to insert EZ-IO first or Pediatric Nio first into a striped piglet long bone. The procedure was video recorded and intraosseous placement was verified by flushing with a colored fluid. Procedure success was determined by 2 independent researchers that were blinded to both the device and the participant identity. Primary outcome measure was procedure success rate. Secondary outcome measures were the success rate with each device, device preference by the participants and device ease of uses assessed by a 5 point Likert scale.

Results: Nurses succeeded in intraosseous insertion in 27 of 34 attempts (79.4%) compared to 25 of 30 attempts by the paramedics (83.33%, P>0.05). The success rate in the first device didn’t differ significantly between the two groups. Success rate was comparable between Nurses and Paramedics when comparing each device separately (76.4% vs 80%, P>0.05 for Nio and 82.4% vs 86.7%, P>0.05 for EZ-IO respectively). Both nurses and paramedics preferred the use of EZ-IO over Nio (82.3% of nurses and 76.9% of paramedics).

Conclusions: In our model, novice nurses had high success rate in intraosseous device insertion, which was similar to the success of paramedics. 


Oren FELDMAN (Ramat Gan, Israel), Najib NASRALLHA, Roni SHAVIT, Yuval BITTERMAN, Hadas KNAANI, Danna MAROM, Itai SHAVIT
08:30 - 17:40 #11004 - Intravenous Systemic Thrombolysis in Hemodynamic Instable Pulmonary Embolism: A Nationwide Population-based Study Analyzed Like Randomized Experiments.
Intravenous Systemic Thrombolysis in Hemodynamic Instable Pulmonary Embolism: A Nationwide Population-based Study Analyzed Like Randomized Experiments.

Objective:

To determine the potential benefits and risks of systemic thrombolytic therapy in pulmonary embolism (PE) patients with extreme hemodynamic instability.

Methods:

This prospective analytic cohort study used administrative data from Taiwan’s National Health Insurance Research Database. PE patients who received inotropic support between January 1, 1997, and December 31, 2011, were enrolled. To closely mimic a randomized experiment, anticoagulation and thrombolysis plus anticoagulation groups were propensity score-matched according to demographic characteristics, comorbidities, and inotropic agent dosage. The primary outcome was in-hospital mortality, and secondary outcomes were intensive care unit (ICU) intervention, cardiovascular complications, bleeding events, and 3-month mortality after discharge.

Main Results:

820 patients, including 164 thrombolysis plus anti-coagulation and 656 solely anti-coagulation, were enrolled. The in-hospital mortality was 48.2% in thrombolysis and 52.4% in anti-coagulation group (P=0.310). The average length of ICU stay was 8.4 days in thrombolysis group and 9.9 days in anti-coagulation group (P<0.001). Mechanical ventilation support was used in 79(48.2%) thrombolysis and 341(52.0%) anti-coagulation patients (P=0.360). Heart failure, acute myocardial infarction, pulmonary hypertension, and atrial fibrillation were recorded in 13(7.9%), 12(7.3%), 4(2.4%), and 2(1.2%) thrombolysis patients and 35(5.3%), 31(4.7%), 15(2.3%), and 14(2.1%) anti-coagulation patients, respectively. Major bleeding occurred in 19(11.6%) thrombolysis and 57(8.7%) anti-coagulation patients (P=0.261). The post-discharged mortality in the thrombolysis and anti-coagulation groups were 15.3% and 17.6% (P= 0.670).

Conclusions:

Systemic thrombolytic therapy does not significantly improve mortality or complications in hemodynamically unstable PE patients. However, it could reduce the length of hospitalization and ICU stay.


Tien-Hsing CHEN, Yuan LIN (Keelung, Taiwan), Hsinkuan WU
08:30 - 17:40 #11210 - Intubating laryngeal mask: a comparative study between nurses and physicians in out-of-hospital cardiac arrest.
Intubating laryngeal mask: a comparative study between nurses and physicians in out-of-hospital cardiac arrest.

Introduction

Since the consensus conference in 2010 concerning managing a cardiorespiratory arrest, tracheal intubation remains the gold standard in securing the airways. The role of supralaryngeal devices for airway management in out-of-hospital cardiac arrest (OHCA) remains controversial. The aim of this retrospective observational study was to evaluate the feasibility and effectiveness of intubating laryngeal mask airway (ILMA) when used in out-of-hopsital cardiac arrest.

Methods

We conducted a retrospective, observational study comparing use of ILMA by nurses and physicians in OHCA. The primary outcome was the success rate of ventilation with ILMA, while secondary outcomes were success rate of tracheal intubation through ILMA and the incidence of regurgitation.

Results

Among 1092 interventions during 9 years, we identified 1070 performed by emergency nurses and 22 by physicians. Ventilation was possible in 84,29% cases for de nurses and 86,35% for physicians after mask insertion but before intubation. Obstruction or major leaks were observed in 8,13% in nurses group and in 4,54% in physician group. After intubation through ILMA, ventilation was possible in 59,09% in physician group and in 77,09 in nurse group. Regurgitation of gastric content occurred to 130 patients (13,35%), in 8,42% cases before arrival of first aid team.

Discussion: 

This study demonstrated that, in the hands of a trained emergency nurse, the use of the ILMA is feasible and allows effective airway management during OHCA. The success rate of the  tracheal tube placement through the ILMA was also high. The incidence of regurgitation in this study was lower in comparison to face-mask ventilation reported in historical studies.

The observed success rate of the insertion of ILMA in this study is similar to that previously reported in studies conducted in the operating room or in the prehospital setting and the observed insertion success rate is higher that the rates reported with the others supraglottic devices. Emesis can occur following cardiac arrest due to vagal stimulation or gastric distention after inappropriate bag mask ventilation. In the present series, the incidence of regurgitation during OHCA was lower that previously reported.

Based on the existing limited literature on prehospital ILMA use by non physician professionals, our service has adopted the use of ILMA for OHCA when managed by prehospital emergency nurses. In this context, ILMA has become the standard care in our district for the nurses.

Conclusion

The use of ILMA for airway management by trained emergency nurses during OHCA resuscitation is feasible and allows an effective airway management. The success rates of tracheal tube placement through the ILMA were high. In addition, when using the ILMA the incidence of regurgitation was lower than that in previous historical reports with face-mask ventilation. 


Laura DASCALU (STRASBOURG), Laurent TRITSCH
08:30 - 17:40 #11313 - Intubation in status epilepticus in children: the experience of a tertiary hospital.
Intubation in status epilepticus in children: the experience of a tertiary hospital.

BACKGROUND: 

Status epilepticus is defined as a prolonged seizure (lasting more than 30 minutes) or recurrent  episodes without return to baseline level of consciousness. It is a pediatric emergency with an estimated incidence of 18-23 cases per 100,000 children per year and a mortality rate of 2% - 7%. Management includes initial stabilization of airway, breathing and circulation and prompt administration of anticonvulsant agents. Benzodiazepines are first-line treatment whereas, in case of failure, a second-line agent is chosen, such us phenytoin, valproic acid or phenobarbital. If seizure activity has not been controlled, then refractory status epilepticus is established and anaesthetic agents are administered. Intubation may be necessary in any step of management for airway protection, ventilation support or to control prolonged seizures.

 

METHOD:

We studied 62 children, aged 4 months to 14,5 years, admitted to PICU of a tertiary hospital from January 2013 to March 2017 with the diagnosis of status epilepticus. Cases with traumatic brain injury were excluded. We reviewed patients who were intubated, their characteristics, the step of management in which intubation happened as well as the causes that led to this decision.

 

RESULTS:

Of 62 patients admitted to PICU due to seizures, 33 (53,2%) were intubated. 22 were males and 11 females ( 66,7% vs 33,3%). The mean age of intubated patients was 5,12 years (5,5 months – 14,6 years) and the mean duration of mechanical support was 18,6 hours (2-72 hours). 18 patients (54,5%) were intubated in another hospital, 4 (12%) in the emergency department, 3 patients (9%) were hospitalized in the ward before having seizures and 8 (24,5%) had undergone late intubation, hours to days after their PICU admission. In the majority the cause of intubation was persistence of seizures (18 patients-54,5%), whereas 6 children (18,5%) had respiratory insufficiency  as an adverse effect of medicines and needed ventilation support. 4 patients (12%) needed intubation for airway protection because of depressed consciousness, while the 5 remaining patients (15%) had to be intubated after seizure control, in order to be transferred to a hospital with neurological department. Among intubated patients, 11 (33,3%) had an underlying disease,  5 (15%) a previous history of seizures activity, whereas 16 had no medical history. It is worth noticing that in 4 patients with status epilepticus which required further intervention the cause was central nervous system infection.

 

CONCLUSION:

Despite published guidelines for the management of status epilepticus, limited data describes the frequency, timing and indications for endotracheal intubation. The decision is individualized and depends mainly on the experience of the healthcare professional.


Alexia PAPATHEODOROPOULOU, Konstantina MITROPOULOU (Zografou, Athens, Greece), Aristoula PATSOURA, John PAPADATOS
08:30 - 17:40 #11259 - Investigate the factors that affect the smooth and efficient operation of the Emergency Department.. The case of Paphos and Paralimni Generals Hospitals of Cyprus. Original research.
Investigate the factors that affect the smooth and efficient operation of the Emergency Department.. The case of Paphos and Paralimni Generals Hospitals of Cyprus. Original research.

Background: The accident and emergency department is the section of the hospital that aims receptions, health, diagnosis, and treatment of patients with a wide range of problems. However in recent years scientists have found that a combination of factors can affect the operation of the Emergency department and make the access for the patients very difficult.  The aim of this study was to investigate the various factors and how much they influence the operation of the Emergency departments of  Paphos and Paralimni General Hospitals.

Methods: This research was carried out during April and May 2016. This is a quantitative research with a total of 409 patients who visited A&E. The survey was conducted using the questionnaire Hospital Urgency Appropriate Protocol (HUAP). The first part was completed by triage nurses and concerns the justified use of A&E. The second part of the questionnaire was supplemented by patients only in case of unjustified use of A&E.  Statistical analysis was performed with the program spss.

Results: The survey involved 409 patients, 300 (79.3%) from Paphos General Hospitals, and 109 (26.7%), From Paralimni General Hospital. The majority concerned males (52.8%), aged less than 45 years old (53%). Of the patient rate 62.6% reported that they don’t work. From the triage categorization scale a rate of 80.2% belonged in the 4-5 scale. The 63.5% was found that it could be served in primary care.

Discussions: These results confirmed that several expected factors such as poverty, unemployment and the lack of insurance coverage increases the numbers of patients ending up in the emergency department. Furthermore, although the triage categorization scale most patients were enrolled in the 4-5 scale, however they didn’t prefer to visit the primary health care as they supported that they trust more the accident and emergency department.


Andri EFSTATHIOU (Limassol, Cyprus), Eleni JELASTOPULU, Dafni KAITELIDOU, Mikaella SYMEOU, George CHARALAMPOUS
08:30 - 17:40 #11726 - INVESTIGATION OF CVD PATIENS RECEIVED IV T-PA IN EMERGENCY DEPARTMENT.
INVESTIGATION OF CVD PATIENS RECEIVED IV T-PA IN EMERGENCY DEPARTMENT.

Cerebrovascular disease (CVD) is a syndrome that occurs with sudden deterioration of blood flow in the blood vessels of the brain. Thromboembolic events or occlusions result in ischemic strokes and these account for approximately 70-80% of total stroke cases. It is the second most common cause of death in the world following cardiovascular diseases in the population of 60 and older. In Turkey, cardiovascular diseases are the leading cause of death with 21.7% and cerebrovascular diseases are in the second place with 15%.

This retrospective study was performed with 65 patients who received intravenous t-PA due to the diagnosis of ischemic CVD between January 2010 and December 2015 at Erciyes University Medical Faculty Emergency Department. Demographic data of the patients such as; age, gender, smoking history, use of anticoagulation and/or anti-aging drugs, and chronic illness were obtained via examining the medical records. Glasgow Coma Scale (GCS), NIHSS scores at the admission, time to admission, and application time of t-PA, blood parameters, imaging modalities (CT, MRI), whether the hemorrhagic complication existed secondary to t-PA were evaluated. The duration of starting to the t-PA treatment, NIHSS scores at the time of admission, age of patients, intracerebral hemorrhage complication and mortality were assessed by independent t test. The chi-square test was used to analyze the relationship among the patient's radiological findings, duration of the t-PA treatment, the anticoagulant/anti-aggregant agent and cigarette use.

46.2% (n:30) of the patients were male and 53.8% (n: 35) of female. The mean age of the patients was 66.2 (min:24-max: 87). Cranial CT scan was performed on all of the patients and there was no acute pathological finding in 78.5% of them. Diffusion MRI was performed on 59.5% of the patients and 23.1% of them had middle cerebral artery (MCA) infarction. The mean time between the occurrence of the event and the time of arrival to the hospital was 70±39 minutes. The time interval between the time of admission to the hospital and the time of receiving t-PA treatment was 59±24 minutes. The mean time between the occurrence of event and the time of application of t-PA treatment was 130±41 minutes. After treatment, haemorrhagic complications occurred in 16.9% of the patients and all of these complications were intracranial hemorrhage. It was seen that; 1.5% of the patients (n:1) died in emergency department and 30.8% (n: 20) died in the intensive care unit. Haemorrhagic complications were detected in 6 of the total 21 died patients after t-PA treatment. NIHSS of all patients with complications was ≥8. There was a significant correlation between intracerebral hemorrhage complication and NIHSS score in accordance with the literature. When the NIHSS score and mortality rates were compared, it was found that; there was a significant correlation between the two parameters and this finding was consistent with the literature data.


Ömer SALT, Necmi BAYKAN, Nesıj Doğan KAYMAZ (EDİRNE, Turkey), Seda ÖZKAN, Halil DÖNMEZ, Emel KÖSEOĞLU, Şule YAKAR, Polat DURUKAN
08:30 - 17:40 #10626 - Investigation of the Patients’ Etiology Admitted to the Emergency Department With Shock.
Investigation of the Patients’ Etiology Admitted to the Emergency Department With Shock.

OBJEKTİVE


Gulnihal SAMANLIOĞLU, Yuksel GOKEL, Ufuk AKDAY (ADANA TURKIYE, Turkey)
08:30 - 17:40 #11273 - Investigations for the assessment of patients presenting to the emergency department with supraventricular tachycardia.
Investigations for the assessment of patients presenting to the emergency department with supraventricular tachycardia.

AIM: Patients with supraventricular tachycardia (SVT) commonly present to the emergency department. Current guidelines do not specifically advocate the use of adjunct investigations. The aim of this study was to determine the utility of commonly requested investigations in the ED among patients presenting with atrioventricular nodal re-entry tachycardia (AVNRT) or atrioventricular re-entry tachycardia (AVRT).

METHOD: A retrospective cohort study was conducted, including all patients that presented to a level IV adult emergency department over a 3 year period (2014 to 2016 calendar years) with the presenting compliant or discharge diagnosis of SVT. Patient ECGs were reviewed to confirm the population of interest and data regarding investigations and management were extracted using an explicit chart review. The exposure variables of interest were five pre-determined commonly requested pathology results: Full bood examination (FBE), Thyroid function tests (TFT), serum electrolytes, troponin levels and chest x-rays.

RESULTS: There were 227 patients included in this study with an average age of 52.6 years and 131 (57.7%) were female. Of these patients, 213 underwent at least one of the pre-specified investigations. There were 126 (59.1%) patients with at least one abnormal pathology result. Among these, 20 patients (15.9%) had focused management of the abnormality. The management included potassium supplementation in 12 patients, magnesium supplementation in six, antibiotics in one and thyroxine in one.

CONCLUSION: Abnormalities after investigations among patients presenting with AVNRT and AVRT are common. However, only anomalies in serum potassium and serum magnesium were associated with clinical management in the ED. These findings question the role of routine pathology testing for patients presenting with paroxysmal SVT to the ED.


Harith FERNANDO, Biswadev MITRA (Melbourne, Australia), Nicholas ADAMS
08:30 - 17:40 #10649 - Is ABG(Arterial blood gas) necessary in all COPD (Chronic obstructive pulmonary disease) Patients ?
Is ABG(Arterial blood gas) necessary in all COPD (Chronic obstructive pulmonary disease) Patients ?

Introduction:

COPD is very common condition. (1,6). Exacerbations of COPD is second most common cause of emergency hospital admissions in UK with an estimated 94,000 emergency admissions per year (6). Current practice is to perform ABG in all COPD patients and then assess acidosis (pH) and respiratory function (pO2 and pCO2).

However, ABG is more painful for patients (6-13,14), technically more difficult and has higher incidence of failure rate and complication rate than venepuncture (6,8-10) so adherence with policy of performing ABG in all COPD patients is not pragmatic.

Aims and Objectives of Clinical Topic Review:

In absence of hypercarbia (pCO2 less than 6.0) and acidosis (pH greater than 7.35) on VBG (and SaO2 on pulse oximeter between 88% - 92%), can we rely on VBG alone in making clinical decisions? (e.g. need for NIV)

Method:

I did literature search by using MEDLINE, EMBASE, CINAHL databases ((1946 to week 4 Dec 2016) via NHS Evidence interface). Cochrane database, BestBETS databases.

Inclusion Criteria: VBG/ABG in adult patients with COPD in Emergency Department.

Exclusion Criteria: Diabetic Ketoacidosis, paediatric patients, patients on mechanical ventilator, VBG/ABG analysis during cardio-pulmonary resuscitation (CPR), foreign languages articles.

Results:

Total 116 papers were identified. 16 papers are relevant and appraised; 12 original studies, 1 review article and 3 meta-analyses.

Summary of evidence: Various studies (6, 7, 8, 9, and 14) showed excellent agreement between arterial and venous pH values, many studies (6, 7, 8, 9, 14, 17) showed close agreement for HCO3. Peripheral VBG is a good screening test for detection of hypercarbia as demonstrated by Kelly et al 2002 (11) and AK et al 2005 (8). All studies are prospective, single-centre studies. All have small sample size but collective results (including all three meta-analyses) showed similar results.

Personal work: I did prospective study in Emergency Department and assess level of agreement between arterial and venous values regarding pH, HCO3 and pCO2 and I suggest new COPD guidelines for management of COPD in Emergency Department.

Prospective Study: 20 consecutive patients with AE-COPD selected. I looked for pH, pCO2, HCO3 and assessed level of agreement between arterial and venous blood gas values by using Bland-Altman plot.

My personal work also indicates good agreement between venous and arterial blood gas pH values. We able to identify all patients with hypercarbia based on VBG alone during our study.

Conclusion & Recommendations:

Level of agreement between arterial and venous values for pH is excellent and in absence of acidosis (Defined as pH < 7.35) and hypercarbia (Defined as pCO2 > 6.0 KPa) on VBG there is no need to perform ABG in patients with acute exacerbation of COPD.

I suggest new COPD guidelines in our trust which can avoid performing ABG in all patients. 


Nauman ARSHAD (Doha, Qatar)
08:30 - 17:40 #11931 - Is air all over.
Is air all over.

We present the case of a 27 years old male who came to emergecy department after an assalt. He was complaing of neck pain and mild shorthess of breath.

On examination : tender over aterior and posterior neck with crepitus felt over larynx and tyroid cartilage. Investigation reveald subcutaneous emphasyma over the soft tissue of neck structures. CT neck  thorax abdomen and pelvis with contrast was performed and showed subcutaneus ephysyma over the neck and pneumomediastinum. no deffenate cause of air leakage is identifided. Although small tears in the airway are one cause of the subcutaneous tissue they can be liftreatening and easly missed on examination. Our case showed no particular tear in the airway and no esophaghial rupture. A large cases of pneumomediastinum are idiopathic and no causes is found. Patient was transfered to an ENT service for MRI of larynx witch was normal.


Octav CRISTIU (Duleek, Ireland), Ahmed JAMAL, Petrovici DANA
08:30 - 17:40 #10939 - Is asthma the only underlying cause of the respiratory symptoms showed by a young man?
Is asthma the only underlying cause of the respiratory symptoms showed by a young man?

Objective: The description of this case is due to the rarity of this clinical entity and its semiotic diversity that implies a high level of suspicion for a correct and quick diagnosis.

The case describes a 17-year-old male who presented to the A&E department complaining of odynophagia and cervical pain from 2 days ago. He also complained of haemoptysis in the last 24 hours. He started with shortness of breath, mild in severity, and several bouts of intense cough 5 days ago after touching a rabbit His GP doctor prescribed him antihistaminic and dry powder inhalers, which didn’t improve his respiratory symptoms. No fever, no shivering. He denied any similar symptom in the past.

Past medical, social, surgical and family history

He also denied any use of illicit drugs or any history of trauma. He had a history of asthma but he was on no prescription medications and participated in sports without any difficulty. He did not smoke or drink alcohol.

Physical examination

Blood pressure was 133/79 mmHg, HR 95 bpm, temp. 36.4ºC and RR was 24/min, SpO2 97% on room air.

He was well developed but in mild respiratory distress.

HEENT: crepitance felt in the right supraclavicular area. Otherwise unremarkable. Trachea was in the middle.

Chest: clear to auscultation bilaterally. No stridor

Heart: No murmurs, rubs or gallops. Regular rate and rhythm.

Abdomen: no remarkable

No pedal edema was appreciated.

No focal findings of neurological deficits.

Next step in the management of this patient

A PA chest X-ray (posteroanterior and lateral view) was done, which showed a slight layer of air surrounding the cardiac silhouette, right chest wall and extensive subcutaneous emphysema in supraclavicular area.

Development

He was admitted to the hospital, followed up of a chest X-ray within 12-24 hours to detect any progression or complications. Treatment included analgesia, rest, and initial oxygen therapy. He was discharged on the 5th day of hospitalization and there were no signs of recurrences.

Summary

The diagnosis of spontaneous pneumomediastinum in an acute hospital setting can present as a challenge. Pneumomediastinum should not be confused with other pathological conditions such as interstitial emphysema, pneumothorax and pneumopericardium, which mostly require specific types of management. Spontaneous pneumonedistiinum is rare in adults, with young male being the most frequently affected, with a male/female ratio of 8/1. Based on previous studies, the prevalence of spontaneous pneumomediastinum ranging from 1 per 800 to 1 per 42,000 patients presenting to a hospital emergency department. Of these cases, approximately 1% has a history of asthma. The natural course is for the pneumomediastinum to spontaneously resolve.


Patricia BAZAN, Elena AZNAR, Raquel CASERO, Virginia ALVAREZ, Marta MERLO (MADRID, Spain)
08:30 - 17:40 #9959 - Is Education Program with Chest Compression during Pre- or Post-shock Pause Effective?
Is Education Program with Chest Compression during Pre- or Post-shock Pause Effective?

Background: To evaluate whether the education of chest compression during automated external defibrillator (AED) charging is useful or not.

Methods: The enrolled who were certified the basic life support (BLS) program of Korean Association of Cardiopulmonary Resuscitation (KACPR) were divided the group with doctor, nurse, emergency medical technicians (EMT) and public persons. They performed the one cycle cardiopulmonary resuscitation (CPR) and then AED operation after delivered by helper. At this time, we evaluated and analyzed all sequences and abilities with KACPR evaluation sheets.

Results: Twenty-nine (10.1%) doctors, 89 (30.9%) nurses, 30(10.4%) EMT and 140 (48.6%) public persons participated in the study. In BLS sequence, the mean time of one cycle was 33.2 seconds and the performance completion was mean 96.7 of 100 points. Nurse (10.9 ± 1.8) was lower than doctor (13.1 ± 1.4) or EMT (13.8 ± 2.0) when we evaluated the mean rate of chest compression during charging of AED (p < 0.001). On chest compression within 2 seconds after shock, EMT was faster than nurse (p < 0.001). With comparison between healthcare provider (HP) and general public (GP). HP (35.4 seconds) was shorter than GP (36.9 seconds) in AED operation mean time (p < 0.001). The mean rate of chest compression of HP (11.9) was higher than GP (5.5) (p < 0.001).

Conclusions: The education of chest compression during AED charging was useful to doctor and EMT and relatively nurse. However, the public was ineffective or have to find a mechanical way to add a voice message on AED operation.


Ho Jung KIM (SEOUL, Republic of Korea)
08:30 - 17:40 #11949 - Is it just an arm pain?
Is it just an arm pain?

We present the case of a 54 years old male patient presented to the emergency department with pain over the anterior aspect over forearm with numbness and loss of sensastion over the area. On assessment he had an isolated c7/c8 sensory deficit but no motor deficit. On background he had a renal transplant and a hemangioblastoma in the brain that was removed. His blood results revealed a normal urea and creatinine with a microcitic anemia Hb 10.2. An MRI of the spine was performed that showed a cystic lesion at the level of C6-T2 consistent with an haemangioblastoma with swelling of the cord as a result. Patinet was diagnosed with Von Hippel Landau Disease and he has mounthly follow up by the neurolgy team and renal team. Initally we could not find why he had a renal transplant. The disease form cysts predominantly in the kidneys and central nervous system. As emergency physicians we need to investigate more closly isolated neurological deficitcs with no other findings to exclude more sinister causes nor simple ones as showed in this particularry rare case.


Octav CRISTIU (Duleek, Ireland), O'connor NIALL
08:30 - 17:40 #11979 - Is RIPASA score more accurate than Alvarado in acute appendicitis?
Is RIPASA score more accurate than Alvarado in acute appendicitis?

INTRODUCTION – Acute appendicitis is a common and important cause of abdominal pain in emergency department patients. Delayed diagnosis of acute appendicitis can lead to adverse outcome and increased mortality and morbidity. Identifying the rapid and simple diagnostic methods can lead to decreased complication.
OBJECTIVES- This study was conducted to evaluate the diagnostic role of procalcitonin in diagnosis of acute appendicitis in emergency department patients.
METHODS- Emergency department patients with complaint of right lower quadrant pain and primary impression of acute appendicitis were enrolled in study and followed up. 340 patients were analysed and sensitivity, specificity, positive and negative predictive value and diagnostic value of Alvarado and RIPASA scoring systems were determined in comparison with histopathologic findings.
RESULTS- Sensitivity, specificity, positive and negative predictive value and diagnostic value of Alvarado were resprctively 57%, 89%, 98%, 18% and 60%. Sensitivity, specificity, positive and negative predictive value and diagnostic value of RIPASA were resprctively 85%, 86%, 98%, 34% and 85%.
CONCLUSION- RIPASA was a more accurate scoring system in diagnosing the acute appendicitis in emergency department patients.


Dr Reza MOSADDEGH, Dr Reza MOSADDEGH (Tehran, Islamic Republic of Iran), Mahdi REZAI, Ghazaleh MIRZAPOUR
08:30 - 17:40 #11291 - Is severe trauma patient really a surgical patient?
Is severe trauma patient really a surgical patient?

Blackground. Major trauma is the sixth leading cause of death worlwide. Among those under 35 years of age, it is the leading cause of death and disability. Traficc accidents alone are the main cause, fundamentally in low and middle-income countries. No worldwide, standardized definitions exist for documenting, reporting and comparing data on severely injured trauma patients. 

The aim of this study was to analyse those patients with severe trauma from Fuerteventura and southern area of Gran Canaria. Knowing the management of these patients, their mechanisms of injury, potentially serious injuries, mayor complications and mortality intends to reach earlier correct diagnoses and improve survival, and also facilitates the elaboration of comparable measures for outcome predictions

Methods. An observational descriptive tranversal study was performed, selecting severe trauma patients from Fuerteventura and southern area of Gran Canaria between 2010 and 2016 (n=985). We analysed epidemiology features, mechanisms of injury, potencially serious injuries, urgent surgical indication, mortality and prognosis

Results. A total of 985 severe trauma patients were analysed. The most frequent age range is between 25 and 44 years, predominantly males (77%). Precipitation is the most common cause of major trauma in our series (30%) followed by traffic accident by collision (27.3%), pedestrian hit (11.8%), white weapon (5.5%), burned (1.4%) and others (falls 8.1%, flattening 2.3%, aggression 2.2%). The lesional distribution is variable occupying the first place the limb trauma (30%) followed by severe head trauma (24.5%), thoracic trauma (17%), abdominal and pelvic trauma (7%) and different combinations in more variable lesional territories (23%). Distribution attributable to overtriaje and different inclusion criteria in national registers where mayor head trauma is first in frequency. Only 1% of severe trauma required urgent laparotomy thanks to the implementation of damage control strategies, diagnostic improvements with angioTC and the greater activity of Interventional Radiology. Almost half had a high ISS (The Injury Severity Score) and TRISS (Trauma and Injury Severity Score), 53% were RTS (Trauma Score) less than 12points and were considered severely injured trauma patients.

Conclusions. Major trauma in the sixth leading cause of death worlwide. Thanks to specialized training courses in the severe trauma patient dierected at physicians, paramedics and nursing such as Advanced Trauma Life Support (ATLS), initial management has improved, and with it, survival and pronosis. The indication of laparotomy is also less due to the influence of diagnostic improvements and greater activity of Interventional Radiology. Also ATLS performs an approach based on injury mechanisms that normally require urgent surgery unlike our sample in which surgical cases are scarce. It will be interesting to increase specific training and target the severe non-surgical traumatized patient.


Barbara MARTIN GINER (MADRID, Spain), Francisco SOSA PÉREZ
08:30 - 17:40 #11204 - Is simulation a useful tool in accident and emergency induction?
Is simulation a useful tool in accident and emergency induction?

Background

Induction is often used to ease the transition of new trainees into the emergency department. Simulation is a way to help this transition but can be expensive. A previous study showed that the more junior doctors (F2 trainees) entering A&E at St Thomas’ Hospital found simulation useful as part of induction. Further study is needed to better assess the value and cost-effectiveness of simulation in this setting.

 

Objectives

To assess whether emergency department induction without simulation training is as valuable to F2 trainees as induction with simulation training. To assess if this should be introduced routinely as part of F2 induction

 

Methods

18 F2 trainees entering the emergency department in their third rotation, were given an induction programme without simulation training. They were then given a retrospective quantitative and qualitative questionnaire regarding their induction.

These results were compared to a previous study of F2s who completed induction with simulation training in their first rotation.

Results

The majority of both groups were apprehensive about starting A&E, 92.31% (n=26).

A higher percentage in the simulation group reported that induction made them feel more at ease (75% n=8), compared to the group who did not have simulation 70% (n=18). While 100% (n=8) of F2s who had simulation training found it useful, only 55% (n=18) of the group who had induction without simulation training felt simulation would have been useful. Despite this 62.5% (n=16) of those who did not have simulation felt it should be routinely included in all departmental inductions, 100% of those that took part in the simulation felt it should be expanded to all departments. Answers to the estimated cost of 30mins of simulation per doctor, ranged from £20-1000 with a mean of £133.

 

Discussion

Simulation is useful when training healthcare professionals. It is clear that those undergoing simulation training in induction find it useful. What remains unclear is whether it significantly improves the quality of induction. The percentage of trainees feeling more at ease after induction was slightly higher following simulation training. The trainees in the group without simulation training were 8 months more experienced, had other simulation training prior this A&E rotation, and had previously worked within the hospital trust. This may account for why they may not all have felt simulation would have been useful in induction. Despite this, more than half felt that simulation would be a useful induction tool across all specialties. One can assess the subjective effectiveness of simulation in making trainees feel more at ease, however making a judgment on cost-effectiveness is more challenging. It is difficult to ascertain whether simulation helped to increase efficiency, reduce waiting times or improve quality of care for patients.


Gabrielle PRAGER, James PERERA, Eleanor STEWART, Shumontha DEV, Savvas PAPPASAVVAS (, Cyprus)
08:30 - 17:40 #10832 - Is the duration of patient symptoms predictive of acute myocardial infarction?
Is the duration of patient symptoms predictive of acute myocardial infarction?

Background: In the Emergency Department (ED), inquiring about the duration of presenting symptoms is commonly done when evaluating patients with suspected acute myocardial infarction (AMI) as it is thought to help distinguish between an AMI and non-AMI diagnosis (long duration to be less likely AMI). Although numerous studies have clarified that chest pain duration positively correlates with infarction size/severity and functional status, much less is known about how presenting symptom duration relates to the presence of AMI.

 

Methods: Patients who were clinically evaluated in a single urban ED from May, 2013 to April, 2015 for suspected AM were prospectively studied. Patients were asked by trained research personnel the length of duration of their predominant presenting symptom. The diagnosis of AMI was adjudicated by two independent physicians (with a third used if there was disagreement) in accordance with the 3rd universal definition of AMI and using the clinically available Siemens Ultra troponin I values (99th% 0.04ng/ml). Exclusion criteria included acute trauma, distress requiring immediate life-saving intervention, cardioversion or defibrillation or receiving thrombolytic therapy within 24 hours, STEMI requiring immediate reperfusion, pregnancy or breast feeding, or if previously enrolled in the study.

Results: There were 569 patients enrolled into the study and 44 (8.0%) had an adjudicated AMI. The presenting symptoms were comprised of chest pain 485 (84.9%), shortness of breath 50 (8.8%), palpitations 14 (2.5%) syncope 6 (1.1%), dizzy/lightheaded 6 (1.12%), epigastric/abdominal pain 5 (0.9%) and other 3 (0.5%). The mean duration of symptoms in the 44 AMI patients was 14.5 hours (± 33 hours) and in the 525 non-AMI individuals 17.9 hours (± 54.0 hours) (p=0.313). The median symptom duration in the AMI group was 3.0 hours, compared to 3.4 hours in the non-AMI group (p = 0.313).Additionally analysis of the duration of the presenting predominant symptom in discrete time intervals (0-19 min, 20-59 min, 1.0-2.9 hours, 3.0 -5.9 hours and > 6 hours ) did not show a significant difference between AMI and non-AMI patients (p=0.525).

Conclusions: As patients with atypical presentations are more likely to experience worse outcomes, discovery of an accurate diagnostic method is paramount when it comes to quality patient care. Most patients who end up being found to have AMI in our urban acute setting are symptomatic for a prolonged duration of time, but as our research reveals, this cannot be used a predominant predictor. Brief reported chest pain and ischemic symptom duration (< 20 minutes) is unlikely to be myocardial infarction. Overall the duration of the presenting predominate symptom, chest pain or otherwise, does not help identify those patients having an AMI. Other elements of the symptom history of an ED patient with suspected AMI should be used in helping differentiating AMI from those without AMI.

 


Richard NOWAK (Detroit, USA), Daniel HRABEC, Michael HUDSON, Michele MOYER, Gordon JACOBSEN, James MCCORD
08:30 - 17:40 #11428 - Is warfarin usage a risk factor for osteoporotic fractures? A cohort study in the emergency department.
Is warfarin usage a risk factor for osteoporotic fractures? A cohort study in the emergency department.

Background: Several studies have examined the association between warfarin sodium use and risk of osteoporotic fractures with conflicting results. Our study address this question, for the first time regarding patients attending an emergency departments (ED)

Objectives: The aim of this study was to retrospectively detect whether there is a higher prevalence of osteoporotic fractures in patients attending an ED.

Methods:  This is a retrospective study from patients' computerized charts. All individuals >65 years old who had an osteoporotic fracture and attended an ED in a tertiary hospital were compared with a similar group of elderly individuals who attended the ED for a cause other than an osteoporotic fracture.

Results: This retrospective study included 328 patients who were evaluated at tertiary Center ED in the years 2005-2016. Overall, 164 individuals with a typical osteoporotic fracture ( hip -66 patients(40%) , spine- 92 patients(56%) , humerus -4 patients (2%), radius -13 patients (8%) ) were identified and compared with a matched group of elderly individuals who were evaluated in the ED for other complaints. Warfarin sodium was used in 61 individuals (19%) in the entire cohort, 34 in the fracture group and 27 in the non-fracture group (p=0.324).

Conclusions: In elderly patients, attending an ED, warfarin sodium use should not be considered a risk factor for an osteoporotic fracture.


Genady DROZDINSKY, Shachaf SHIBER (Tel aviv, Israel), Alon GROSSMAN
08:30 - 17:40 #10960 - Ischemia of upper extremity and brain after metoclopramide injection.
Ischemia of upper extremity and brain after metoclopramide injection.

Introduction: Acute limb ischemia due  to thrombosis or embolism is a true medical emergency requiring  immediate therapy for limb salvage. Diagnosis of acute limb ischemia is based primarily on findings of a detailed history and physical examination. Acute arterial occlusion in the upper extremities is much less common than occlusion in the lower limbs. We aim to present  a case of upper extremity and brain ischemia secondary  intravenous metocloropamid injection.

Case report: 62-year-old female patient admitted to the ED with complaints of  vomiting, speech impairment and meaningless movements. In history intravenous  metocloropamid  had been given due to vomiting 6 hours ago but  because of continuation of  complaints and beginning of disorder of speech and meaningless movements she was brought to the ED by 112 Emergency Medical Service. Vital signs : Tension;135/70 mm-Hg Beat:88/min, Fever:36,6 °C. In physical examination  orientation for person and place were normal but time orientation was decrease and  speech of her was disartic. Right upper extremity was polar and pallor but left upper extremity was normal. Coagulametric parameters revealed  PT:14,1 sec, a PTT:24 sec, INR:1,08. CT angiography showed  occlusion from the brachial artery on right upper extremity. She was operated  because of peripheral emboli (brachial artery embolus) by cardiovascular surgery immediately. After operation  for continuing confusion and motor movement loss on left upper extremity,  planned diffusion MRI  showed  acute multible infarcts with diffuse restriction on MCA irrigation area at the level of the temporoparietal and frontoparietal lobes in the right cerebral hemisphere. She was interned to neurology clinic as a result of cerebrovascular ischemia.

Conclusion: Thrombosis unrelated to atherosclerotic disease can result from hypercoagulable states or can occur at an area of vessel injury caused by invasive catheters, balloons, sites of bypass grafting, or intra-arterial drug injections. Intentional or accidental intra-arterial drug injections by medical personel or those taking illicit drugs can result local vasospasm and thrombosis.


Mehmet UNALDI (Istanbul, Turkey), Ersen GUNDUZ, Didem AY, Soner ISIK, Kurtulus AÇIKSARI
08:30 - 17:40 #11063 - It is not a hernia, it is a catheter.
It is not a hernia, it is a catheter.

Clinic history:
• Personal history: NAMC. Smoker 10 cigars / day. Diabetes mellitus 2. Interventional testicular seminar, also treated with radiotherapy and chemotherapy 30 years ago. Interventioned right inguinal hernia. Usual treatment: Metformin 850 mg: 0-1-0.
• Anamnesis: A 63-year-old man, who appears to have recurrences of a right inguinal hernia that had been involved for years. Note a tumor in the groin area that is increasing and sometimes causes certain discomfort, but not pain. No alteration of intestinal habit. Deny another clinic.
• Exploration: TA: 124/83, FC: 85 bpm, Oxygen saturation: 98% basal. Eupneic. No lymphadenopathy, no jugular engorgement, palpable and symmetrical carotid pulses. ACR: Rhythmic without blows. MVC without pathological noises. MMII: Tumoration is observed in the right inguinal region, of soft consistency, varicose, not palpable hernia. No increase in temperature. No edema, no signs of venous thrombosis, present and symmetrical pulses.
• Supplementary tests:
  - Blood Analytics: No significant findings
  - Doppler ultrasonography of the right lower limb: superficial femoral vein with decreased light occupied by echogenic content with a hyperechogenic linear image ("catheter portion") corresponding to chronic thrombotic changes post-catheterization with increased caliber of the deep femoral vein as well as a saphenous vein with formation from the same of a superficial varicose package towards suprapubic and superficial inguinal region that increases of caliber and is mainly reflected during the Valsalva with present flows and without evidence of recent thrombus in the venous region superficial or deep at that level. Some non specific reactive lymph nodes are seen in the inguinal region. No hernial images are seen.

Conclusions:
Due to the radiological findings and antecedents of the patient it seems to be a portion of a central catheter that has been thrombosed in the area causing a decrease in caliber of the vein wich favors the development of evident collateral circulation. Currently, he is being treated with acenocoumarol and being evaluated by Cardiovascular Surgery to take a definitive therapeutic attitude.
The rupture of an intravascular catheter can cause serious complications that can lead to thrombosis, vascular perforation, embolisms ... Due to the great increase in the frequency of its use it is also possible to expect a greater number of these complications.


David NUÑEZ CASTILLO (SPAIN, Spain), Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO
08:30 - 17:40 #10886 - It looks like a Baker cyst ... but it is not! . About a case.
It looks like a Baker cyst ... but it is not! . About a case.

CLINIC HISTORY

An 80-year-old man who comes to the emergency department for pain in the right lower limb of three days of evolution with a painful tumor at the right popliteal level of 6 cm in diameter and a dubious Hommans sign. The patient had attended up to 4 times previously to the emergency room for the same reason being diagnosed of a possible Baker's cyst and treated with anti-inflammatory drugs without improvement and he returned to consult

The distal pulses are preserved. D-dimer is greater than 10,000. According to the report of the Eco Doppler and AngioTaC carried out: "Large partially thrombosed popliteal aneurysm (51x60 mm)" It is valued by Cardiovascular Surgery that decides urgent surgery.


EVOLUTION.

Three hours later the patient enters a chiropody where a longitudinal arteriotomy is made by extracting thrombotic material and bypass femoropopliteal without incidences. The next day they perform a second intervention due to poor evolution with soft tissues in very poor condition, finally, supracondylar amputation of the right lower limb due to failure of the graft. The aneurysm of the popliteal artery is the main peripheral aneurysm and the second in frequency after aneurysm of the abdominal aorta. It corresponds to 70% of all peripheral aneurysms and its presence is indicative of aneurysms in other territories, mainly the contralateral popliteal artery. From the urgencies we must think about this pathology since if the aneurysm is not treated surgically it can present manifestations of ischemia of the extremity, which are associated even to a 20% of amputations of the same.


DISCUSSION AND CONTRIBUTION OF THE CASE FOR DISSEMINATION.

The aneurysm of the popliteal artery is the main peripheral aneurysm and the second in frequency after aneurysm of the abdominal aorta. It corresponds to 70% of all peripheral aneurysms and its presence is indicative of aneurysms in other territories, mainly the contralateral popliteal artery. From the urgencies we must think about this pathology since if the aneurysm is not treated surgically it can present manifestations of ischemia of the extremity, which are associated even to a 20% of amputations of the same.


Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO, David NUÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #10984 - JLB: an answer to emergency intravenous catheterization in fragile critically ill patients.
JLB: an answer to emergency intravenous catheterization in fragile critically ill patients.

Venous access is a milestone in the management of critically ill patients. In the Emergency Department (ED), positioning a reliable device for fluid resuscitation and drug administration can be challenging and time-consuming; but in the elderly or in pre-terminal patients, often with poor vascular access, to place a central line can be considered an over-treatment. Hence the need of a new device, rapid and safe to place. JLB is a new catheter designed for large and medium caliber veins (internal jugular vein, subclavian, brachial). It is placed bedside under ultrasound guidance and fixed with patches, Steri-strip or non-adsorbable stitches. It can stay in place up to 30 days. It is produced in several lengths (6 - 7 - 8 cm) and gauges (from 14 to 18) and allows high flows up to 283 ml/min. It enables blood sampling. We retrospectively collected data from the emergency ward of the University Hospital of Modena and other two Community Hospitals (Baggiovara, Sassuolo) where JLB has been used since June, 2015. Data included: catheter specs, patient’s characteristics, indications for usage, short-term and long-term complications, length of stay, number of attempts and procedure time (from field disinfection to device fixation). Impaired coagulation status, PLTs <50.000/mmc and minor age were contraindication. Operators were residents and attending physicians with different expertise on vascular access and US-guided procedures. JLB catheter was used in 354 patients mostly in IJV, brachial or subclavian access were chosen as alternative site. (the latter even using landmark technique). The main indication for JLB usage was the lack of any peripheral line in patients with poor venous pool; other indications included: need for aggressive fluid resuscitation, vasopressors or antibiotics infusion. Moreover in 55 cases JLB became an introducing line for the Seldinger guide wire and further CVC positioning. No major complications were recorded, neither during the first 24 hours post-procedure, nor the following days. Two minor complications (one soft tissue haematoma, one tachyarrhythmia) occurred. The device was removed promptly if there were no indications left; in 16 cases we observed dislocation or malfunctioning (in particular occlusion), leading to removal as well. Mean procedure time was 187 secs, with an average 1,29 number of attempts. Data referring to our 409 cases suggest that JLB can be a smart answer to critical patients who need a quick and reliable vascular access. On the other hand, there is a consistent amount of cases where a CVC can be considered an over-treatment. The introducing procedure appears to be safe, rapid, easy to learn, and can be performed bedside by the trained emergency physician. In conclusion JLB could be considered the ideal device in the ED enabling a rapid and effective intravenous treatment or bridging to more-invasive catheters, only when indicated.


Brugioni LUCIO, Mirco RAVAZZINI, Francesca MORI, Sergio CAMPANALE, Andrea RIGHETTI, Marina BUDA, Federica PIANI (Bologna, Italy), Serena SCARABOTTINI, Elena CARELLA, Elisabetta BERTELLINI, Massimo GIRARDIS, Matteo NICOLINI, Marcello BIANCHINI, Filippo SCHEPIS, Marco BARCHETTI, Giovanni PINELLI, Marco BAROZZI, Giovanni TAZZIOLI, Andrea BORSATTI, Pietro MARTELLA
08:30 - 17:40 #11314 - Keeping Children Safe: Prevention and Management of Accidental Poisoning in Children.
Keeping Children Safe: Prevention and Management of Accidental Poisoning in Children.

Background

Accidental poisoning in children is a common but preventable occurrence. In 2013-14, in the UK, almost 150,000 hospital admissions were due to poison exposure. Thankfully mortality is rare, however injury is still the leading cause of death in children, of which poisoning is the third most common mechanism.

Objective

The aim of this project was to research the incidence of accidental poisoning in children in an accident and emergency department, create an intervention to reduce incidence and improve pre-hospital and immediate hospital management.

Methods

Firstly this project reviewed relevant literature on accidental poisoning in children, in particular focussing on epidemiology, looking at the age groups most commonly affected and the most common and most lethal substances ingested, and also the optimum pre-hospital management. This information was then used to devise a resource for parents, accessible to all, that advises on how to prevent accidental poisoning and what to do if this occurs, in terms of first aid and pre-hospital care. The relevance, usefulness and accessibility of this resource was audited, relevant adjustments made and the resource implemented. Suggestions were also made as to how doctors could aid in the prevention of accidental poisoning and how management could be improved both in the pre-hospital setting and in immediate hospital management.

Results

The results of our review showed that more could be done to prevent accidental poisoning in children and parents felt a general lack of understanding about how to prevent accidental poisoning and what to do if it occurred. Our audit showed that our resource was able to provide parents with useful information and increase their understanding in these areas. In addition we found that better and more comprehensive advice should be given to parents by doctors about particularly dangerous, and often commonly prescribed, substances, such as those lethal in small doses. Furthermore, it showed that pre-hospital and emergency department management of accidental poisoning in children was often lacking and minor adjustments could significantly improve the care of these patients. Further data about the effectiveness of our interventions is forthcoming.

Conclusion

In conclusion, our study highlighted numerous areas in which accidental poisoning could be prevented or managed more effectively and a resource was devised and suggestions made in order to rectify this. This resource could be distributed more widely to see reduction in accidental poisoning incidence not only across the UK, but also in the rest of Europe. Furthermore, the weaknesses idenftified and the changes to pre-hospital and emergency department care are widely applicable to other emergency departments worldwide.


Dr Laura HARRISON (Oxford, United Kingdom), Maric THORPE
08:30 - 17:40 #11229 - Ketamine' use in emergency department: an observational survey.
Ketamine' use in emergency department: an observational survey.

Introduction

Ketamine is conventionally used as an anesthetic agent but it is also interesting for analgesia. However,  guidelines are not available for doses, indications and timing in emergency department (ED) leading to heterogeneity of clinical practices. The objective of our work is to assess the theoretical knowledge and clinical practice of emergency physicians regarding ketamine's use. 

Methods :

A self-reported and anonymous questionnaire was distributed to emergency physicians  (n=64) at a university Hospital. Data were analyzed with descriptive statistics. The questionnaire included questions on demographic data, the type of patients for whom ketamine was prescribed, the doses used, the side effects and safety measures associated with the administration of ketamine. The reasons for a reluctance to use it, if any, have been recorded. Statistics were performed using SPSS.

Results :

A total of 64 questionnaires were analyzed. For indications of Ketamine, analgesia was cited by 87% of responders. Other indications (sedation, anesthesia and induction) were cited respectively in 46%, 28% and 21% of cases.

Forty eight percent of the responders declared that they used ketamine. Analgesia was the ketamine's use first indication (all users), associated with morphine titration in 22% of cases. Doses and modalities of administration have varied but were correct in 87% of cases. Neuropsychiatric side effects  are the most feared adverse effects.

The reasons for a reluctance to use were: lack of sufficient information about the molecule (82%), drug's unavailability  (18%) and absence of an institutional protocol (86%).  

Discussion:

The analyzes of this Ketamine survey in the ED reveal a lack of information about the characteristics and benefits of this drug and its limited use which still focused on analgesia. An institutional updated protocol with consensus on doses, indication and administration' modalities  of ketamine will allow us to adapt our practice. 


Hajer KRAIEM (Sousse, Tunisia), Rabeb MBAREK, Mohamed Aymen JAOUADI, Fatma BOUKADIDA, Majdi OMRI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11464 - Knowledge about fluid responsiveness among Emergency versus Critical Care Physicians.
Knowledge about fluid responsiveness among Emergency versus Critical Care Physicians.

Background: Management of fluid therapy is important as both too much and too little fluid are harmful. Fluid responsiveness (10-15% increase in cardiac output or one of its surrogates after a preload challenge) has been suggested as a dynamic method to titrate resuscitation. This concept has gained much attention in critical care – and to a lesser extent emergency medicine – literature in the last two decades.1 However, the level of uptake of these advances by doctors in developing countries is unknown.

Aim: Evaluation of knowledge, attitude and current practice of fluid responsiveness among Emergency and Critical Care Physicians in Egypt.

Methods: A questionnaire was sent via Surveymonkey to Emergency and Critical Care Residents and Specialists in Alexandria University Hospital, a large urban teaching hospital in Egypt. Mann-Whitney test was used to test statistical significance between groups.

Results: A total of 72 responses were received, 32 from Emergency Physicians (EPs) and 40 from Critical Care Physicians (CCPs). The median years of experience in acute care was 4 (Interquartile range, IQR, 3-5) for EPs and 4 (IQR: 3-6) for CCPs (p value 0.298). The perceived knowledge about fluid responsiveness was not significantly different between the two groups (p 0.07). However, many more EPs stated they predominantly use clinical parameters to guide fluid therapy (75%) compared to only 43% in CCPs. The majority of the remaining CCPs preferred central venous pressure, CVP, (33%) and ultrasound/echocardiography (20%). Both groups similarly used fluid challenge as a dynamic test (88% among EPs and 85% among CCDs). Ultrasound/ Echocardiography was perceived as the ideal method by 44% of EPs and 53% of CCPs.

Discussion: EPs relied more on clinical parameters, whereas CCPs showed more preference to alternative methods. This can be attributed to the more fast-paced pragmatic nature in emergency department. CVP is still regarded as important by CCPs despite criticism in recent literature.2 This may be a form of availability bias – where what is available is regarded as important. Ultrasound/ Echocardiography seem to have gained much popularity. However, it may be that the skill required is not yet well established to translate into practice.

1. Elwan MH, Roshdy A, Elsharkawy EM, et al. The haemodynamic dilemma in emergency care: Is fluid responsiveness the answer? A systematic review. Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine 2017;25(1):25.

2. Marik PE, Cavallazzi R. Does the central venous pressure predict fluid responsiveness? An updated meta-analysis and a plea for some common sense. Crit Care Med 2013;41(7):1774-81.


Dr Mohammed ELWAN (Leicester, United Kingdom), Ashraf ROSHDY, Mahmoud ABDELAZIZ, Joe REYNOLDS, Eman ELSHARKAWY, Salah ELTAHAN, Timothy COATS
08:30 - 17:40 #11279 - Late obstetric emergency: a case of severe ethylene glycol intoxication with full recovery.
Late obstetric emergency: a case of severe ethylene glycol intoxication with full recovery.

Purpose of the study: Ethylene glycol (EG), a common antifreeze, coolant and industrial solvent, is responsible for many instances of accidental and intentional poisoning annually. Following ingestion EG is absorbed rapidly in the gastrointestinal tract, reaching peak serum concentrations within two hours. Consequently, EG is widely distributed throughout the most perfused organs, and metabolised in liver to toxic metabolites (TM). If left untreated, the accumulation of EG TM is responsible for potentially fatal organ dysfunction. Although acute EG intoxication can advance through three noticeable phases: (1) central nervous system depression, followed by (2) cardiopulmonary dysfunction, and (3) renal dysfunction, the onset and clinical course is often not consistent or predictable. In the acute settings, profound anion gap metabolic acidosis, elevated osmolal gap, and elevated ethylene glycol levels can be useful in the diagnosis of the acute EG intoxication. However, EG ingestion during pregnancy presents a diagnostic and therapeutic challenge, because early clinical course may mimic the one of eclampsia and preeclampsia. Herein, we report a rare case of late obstetric emergency after intentional EG poisoning. Case report: A 35-year-old female, at 32 weeks’ gestation, was admitted to our Emergency Department (ED) after ingestion of 500 mL of an antifreeze solution in suicide attempt. The patient presented with consciousness impairment, Kussmaul breathing, and sinus tachycardia. Initial laboratory test results revealed high anion gap metabolic acidosis, significant osmolality gap of 50 mOsmol/kg, and acute renal failure. The urine sediment showed calcium oxalate crystals. At the time, laboratory methods for detecting EG metabolites were not available. Point-of-care trans-abdominal ultrasound findings, utilised for rapid assessment of fetal viability, were unremarkable. Prompt emergent stabilisation consisted of general supportive care, intravenous fluids administration, calcium supplementation, and metabolic acidosis correction with sodium bicarbonate. After consultation with a poison control centre, further treatment focused on EG metabolism inhibition and elimination enhancement of both, un-metabolised parent compound and its metabolites. Hence, due to the shortage of intravenous ethanol and fomepizole, the patient was immediately administered with a single dose of 20 mL ethanol 40% via nasogastric tube along with hemodialysis. The patient was transferred to the Intensive Care Unit for further treatment, which consisted of multidisciplinary management of various medical specialists. She was discharged three weeks after admission with complete clinical recovery. Conclusions: Late obstetric EG intoxication presents time critical presentation in the ED, where rapid recognition and early treatment, including alcohol dehydrogenase inhibition, are crucial and critically important to ensure the well being of both mother and foetus. 


Dr Dinka LULIC (Zagreb, Croatia), Ileana LULIC
08:30 - 17:40 #11174 - Late-phase Safety and Efficacy Results of the Sufentanil Sublingual Tablet 30 mcg for Management of Acute Moderate-to-severe Pain.
Late-phase Safety and Efficacy Results of the Sufentanil Sublingual Tablet 30 mcg for Management of Acute Moderate-to-severe Pain.

 

BACKGROUND: The Sufentanil Sublingual Tablet System (SST 15 mcg; Zalviso®), a patient-controlled analgesia device dispensing 15 mcg tablets, was recently launched in Europe for treatment of moderate-to-severe acute post-operative pain.  A second sufentanil product, a 30 mcg tablet (SST 30 mcg) dispensed by a healthcare professional via pre-filled, single-dose applicator, is now under review by the European Medicines Agency for management of acute pain in medically supervised settings, such as emergency medicine.  SST 30 mcg appears well-suited for trauma applications because it is non-invasive, is rapidly absorbed and possesses a predictable off-set after 2-3 hours duration of effect. The objective of this analysis was to review key efficacy and integrated safety results across the late-phase clinical trials.

METHODS: Four studies were conducted; two randomized and placebo controlled in post-operative patients following bunionectomy or abdominal surgery and two open-label, single-arm trials intended to evaluate SST 30 mcg in the Emergency Department and in older, post-operative patients, many of whom carried comorbidities.  Following execution of an Ethics Committee-approved Informed Consent Form and meeting all entrance criteria, patients were administered SST 30 mcg by a healthcare professional no more frequently than hourly as needed to manage pain.  Efficacy was assessed by patient reports of pain intensity on an 11-pt numerical rating scale (0-10) where 0 = “no pain” and 10 = “worst pain possible”.  Safety assessments included vital signs, adverse events (AEs) and concomitant medications.  Rescue opioids (ie IV or oral morphine) were available upon request.

RESULTS:A total of 479 patients were enrolled; 363 received treatment with SST 30 mcg.  In each placebo-controlled study, SST 30 mcg was superior to placebo for the primary outcome measure of the summed pain intensity difference to baseline (SPID) [p = 0.005 and p < 0.001, respectively]. The open-label trials also provided convincing support for the efficacy of SST 30 mcg.  Specifically, in the Emergency Department, SST 30 mcg demonstrated a 3-pt mean reduction in pain intensity within 60 minutes and across a variety of trauma classifications such as fractures, dislocations, lacerations, sprains/strains and burns. The most commonly reported AEs across all studies were nausea (29%), headache (8%) and vomiting (6%) with no statistical differences between active and placebo.

CONCLUSION: SST 30 mcg has shown benefit across a range of surgical procedures and trauma presentations as a non-invasive analgesic modality for short-term treatment of acute moderate-to-severe pain.


James MINER (Minneapolis, USA), Zubaid RAFIQUE, Harold MINKOWITZ
08:30 - 17:40 #11092 - Lateral Rectus Muscle Injury of Eye After Assault.
Lateral Rectus Muscle Injury of Eye After Assault.

Traumatic rupture of lateral rectus muscle of eye is rare. A case of a 40yrs old male is presented here who was brought with complaint of pain in left eye after an unknown person assaulted him. His primary survey was intact. Secondary survey showed 2.5cm laceration over the outer edge of left eyebrow with conjunctival chemosis and large sub-conjuctival hemorrhage over the temporal aspect of left eye. Vision was 6/6 in both eyes with diplopia on left lateral gaze. Abduction in left lateral gaze was not possible in left eye, where as adduction, supraduction and infraduction was possible. Fluorescent test of cornea showed no corneal injury. Pupil was reactive to light. Intravenous analgesia was given, wounds were cleaned and suturing of the eyebrow laceration was done. Computerized tomography (CT) orbit was done which showed ruptured lateral rectus muscle of the left eye. Surgical repair of left lateral rectus muscle was done with minimal post surgical exophoria.


Muhammad Faisal KHILJI (MUSCAT, Oman)
08:30 - 17:40 #11271 - Left ventricular rupture following blunt thoracic trauma.
Left ventricular rupture following blunt thoracic trauma.

    We present the case of a 32 years old man, who sustained a blunt thoracic trauma (crushed between a truck and a tow). The prehospital evolution was dominated by hemodynamic and respiratory instability, which culminated with cardiac arrest. The aggressive resuscitative efforts ( including 2 chest drains,  autotransfusion ) enabled ROSC and transportation to a hospital with cardio-thoracic surgery capabilities. The most important finding during emergency thoracotomy was a left ventricular  rupture (postero-inferior wall ) ; the patient had also multiple rib fractures, massive left hemothorax , broncho-pleural fistula and pneumothorax , dissection of the  left carotid and internal carotid arteries. The patient was discarded from the hospital one month later, with minimal neurological impairment.

     We found in the literature that left ventricular ruptures following blunt thoracic trauma are rare, and most of the patients die before reaching the hospital. In our case, an early aggressive prehospital  management combined with a high standard of care received in the hospital allowed this patient to survive.

 

 

 


Paul-Bogdan CSILLAG (Sibiu, Romania), Adela FARAIAN, Andreea GANEA
08:30 - 17:40 #11180 - Legionnaires' disease - it's all in the history.
Legionnaires' disease - it's all in the history.

Legionnaires’ Disease is the eponymous syndrome caused by the Legionella bacterium and causes up to 9% of community acquired pneumonias. Transmitted by the inhalation of contaminated aerosols, Legionella has a propensity to cause outbreaks in locales with contaminated water systems, such as hotel air conditioning.

A 50 year old man presents to A and E complaining of a one-week history of lethargy, malaise, vomiting and fever. He was also experiencing left-sided pleuritic chest pain, a non-productive cough and associated shortness of breath. Apart from medication controlled Type 2 Diabetes Mellitus, there was no other past medical history.  He had recently returned from Atlantic City, USA on a business trip, and had stayed in a large, 4,000-bedroom hotel. Examination revealed left sided bronchial breathing and crepitations with reduced air entry. Observations and blood tests were unremarkable apart from a CRP of 221, but an admission chest x-ray showed bilateral pneumonia, more severe on the left. Empiric antibiotics were started, but given the history of travel and the patient’s age, an atypical organism screen was organised. The patient’s urine screened positive for legionella antigen and a diagnosis of Legionnaires’ disease was made. Public Health England was notified and antibiotic therapy was switched to levofloxacin and rifampicin and the patient’s clinical and biochemical condition rapidly improved. He was discharged with 14 days total antibiotics. A repeated chest x ray 6 weeks later showed resolution of pneumonia.

This case is remarkably similar to the very first outbreak of Legionnaire’s Disease, occurring in American Legionnaires attending a convention at the Bellevue-Stratford Hotel in Philadelphia in 1976. 182 Legionnaires were affected, and 29 died. Dubbed the ‘Philly Killer’, the outbreak was tracked by health authorities, who successfully isolated Legionella in the cooling tower of the hotel’s air conditioning.

Antibiotic guidelines for community acquired pneumonia in the UK focuses on empiric treatment for the most common causative organisms; Streptococcus Pneumoniae and Haemophilus Influenzae. This case illustrates the importance of taking a careful history, knowing classical presentations and knowing when to screen for atypical causative organisms and notifiable diseases. 


Joseph BUTLER (Milton Keynes, United Kingdom), Ree'thee BHATT
08:30 - 17:40 #11228 - Leriche syndrome presenting as hypertensive urgency.
Leriche syndrome presenting as hypertensive urgency.

Introduction

Leriche syndrome results from thrombotic occlusion of the abdominal aorta immediately above the site of its bifurcation. It is well described in young male patients as the triad:  intermittent bilateral claudication with ischemic pain, absent or decreased femoral pulses and erectile dysfunction. The obstruction of the abdominal aorta occurs at any site and leads to various symptoms. We report the case of a patient admitted to the emergency department (ED) for chest pain suggestive of non-ST-segment myocardial infarction (NSTEMI).

 

Observation

A 44-year-old man with no medical history except active smoking presented to the ED with complaints of chest pain, buzzing and headache. The initial medical exam showed: Glasgow come scale 15, blood pressure 180/90 mmHg in 2 arms, pulse rate 75 bpm, respiratory rate 15 cpm, oxygen saturation 97 % at room air, normal cardiopulmonary auscultation and no neurological sign.

A 1 mm depression of ST-segment in the inferior and basal territories was noted in the electrocardiogram.  The chest X-ray was normal.

NSTEMI was first suspected and intravenous isosorbide dinitrate was administrated to relief chest pain.

Biological investigations showed elevated high sensitivity troponin levels and a deep hypokalemia (2 mmol/L). A rapid potassium replacement was initiated via a central venous catheter.

Because of unknown and severe hypertension in a young male with a hypokalemia, a reno-vascular disease was suspected and thus a renal ultrasonography was performed. It showed a severe stenosis of the renal artery with obstruction of the abdominal aorta reaching the primary iliac artery. The diagnosis of Leriche syndrome was retained.

The patient was hospitalized in the cardio-vascular surgery department for further investigations. The coronary angiography didn’t reveal significant stenosis. The patient underwent an aorto-bifemoral bypass surgery.

 

Conclusion

Leriche syndrome typically begins at the distal aorta and slowly progresses proximally and distally over time. This progression may ultimately extend to the level of the renal arteries in 3 to 15% and thus can cause increasingly severe hypertension. 


Ines CHERMITI, Sana TABIB (Ben Arous, Tunisia), Hanène GHAZALI, Anware YAHMADI, Hedia GNENA, Ahlem AZOUZI, Mahbouba CHKIR, Sami SOUISSI
08:30 - 17:40 #11978 - Lesion on the pinnae: Chondrodermatitis nodularis helicis.
Lesion on the pinnae: Chondrodermatitis nodularis helicis.

Background: Chondrodermatitis nodularis helicis (CNH) is a painful lesion with benign course which is localized to the helix or anti-helix part of the ear.  Although its incidence cannot be estimated, it frequently occurs between the ages of 60-80 years. The disease mostly affects males. Even though the causes such as trauma, cold, pressure on the lesion side, auto-immune or connective tissue diseases are accused, the definite etiological cause could not be elucidated. The lesion is usually nodular, tender, well-circumscribed, oval or round shaped, elevated from the skin, its middle part is ulcerated or crusted. It is mostly localized to right ear and the helical part of ear. Severe pain sensation, which occurs spontaneously or by touch and which is described by the patients as stinging and sharp pain, is the most frequent cause of admission. After the lesion has emerged, it quickly reaches to its maximum size and remains constant afterwards. This lesion in which spontaneous regression is rare does not undergo malignant transformation. There are many medical and surgical treatment options.

Case: A 73-year-old female patient presented to the emergency service with severe pain in the upper part of left auricle and swelling of the same area. The patient's complaints had begun suddenly about one week ago when she woke up in the morning.  She stated that the pain occurred first and after a few days, the same area began to swell. She had irritated the described painful area with her hand. There was no trauma story for her ear. The past medical history of the patient revealed no systemic disease except COPD. She did not mention any auto-immune or neoplastic disease. She was on inhaler corticosteroid and inhaler beta2 agonist medications. Her vital signs were normal except the decreased oxygen saturation (spO2:89). On the physical examination, the dry, hard, nodular, crusted lesion was localized to helical area of the left ear anteriorly, it was measuring 1x1 cm in size and had gray-brown color (figure 1). The lesion was tender on palpation. There were no pathological findings in other system examinations including the otoscopic examination. The patient who was consulted with the dermatology clinic was diagnosed with "chondrodermatitis nodularis helisis". The patient was discharged with topical antibiotics, topical steroid and analgesic prescription. After the discharge, the diagnosis of the patient was confirmed with a biopsy which was performed in the dermatology clinic.

Conclusion: Although chondrodermatitis nodularis helicisis a well-known clinical entity by the specialist physicians of ENT and dermatology, it is not among common admission causes of emergency. We aimed to present a rare entity of emergency service in this case. 


Ilker AKBAS, Abdullah Osman KOCAK (Erzurum, Turkey), Atif BAYRAMOGLU, Nazim Onur CAN, Zeynep CAKIR
08:30 - 17:40 #11946 - Let's dive.
Let's dive.

We present the case of a 29 years old diver who presented to the emergency department after suddent ascendant from 60 m deep water. He was doing research over a ship. He had a malfunction of the costume and he had a rapid ascendant in about 30s for 40 m . At arrival in the emergency department he was complaing of an headache, left sided chest pain and mild joints pain. His investigations revelead a midly hypoxia p02 (9.34 normal 10) all other bloods within the normal limits. Chest x rays was normal. He was position in the left lateral decubitus with high flow oxigen. He was transffered to the regional hyperbaric medicine unit where he was admitted in the hyperbaric chamber for treatment. He was discharged home in 2 days time with full recovery. Diving emergency are not frequently met but promt recognition of symptoms and transfered of patients to proper care facility can make a big difference in the outcomes.


Octav CRISTIU (Duleek, Ireland), Ahmed JAMAL
08:30 - 17:40 #11220 - Limitation or withdrawal of life support' decision: which barriers in emergency department.
Limitation or withdrawal of life support' decision: which barriers in emergency department.

Background:

Emergency departments are crossroads where people frequently seek urgent care. Diseases and patients' status  are heterogeneous. The physicians have the responsibility to decide about the adequate and ethic approach of some patients which is complex and at times difficult in patients reaching the end of life.

The objective of this study is to determine the difficulties encountered by emergency staff in the management of patients with limitation or withdrawal of life support (LWLS).

Design: A questionnaire survey design.

Methods: A self-reported questionnaire was distributed to emergency staff  (n=56) at a university Hospital. Data were analyzed with descriptive statistics.

Results:

Of the 56 adults included in the study, 26.8% are residents, 58.9% interns and 14.3% seniors.

The LWLS concept was known by 73.2% of the participants. 45.4% had already face this situation in daily practice. 70.9% do not feel comfortable with LWLS's decision. Several barriers to decision making were found: pressure and conflict with the family (22%), lack of information about patient's disease (15.5%), lack of time (17.9%), and ethical difficulties (13.7%). Legal, emotional and technical obstacles coexisted. Only medical staff was involved in most decisions.  The decision of LWLS was often collegiate i.e in consultation with senior and colleagues (64.8%). The main elements involved in the LWLS's decision were age (21.6%), severity of illness (20.2%), limited autonomy (15.6%), acute clinical condition (13,8%) and lack of improvement after well-conducted treatment (10.5%). Resuscitation, intubation and surgery were most commonly withdrawn. The majority of doctors (95%) reached for a national consensus to define LWLS and to help them  through the decision making process. They also wished further training (98%), particularly regarding therapeutic (64%) and legal (83.3%) aspects.

Conclusion:

The decision of LWLS still source of difficulty for emergency physicians. Developing training for improving clinician-family communication is essential. In the future, the establishment of a national consensus of care for LWLS should be a priority.


Hajer KRAIEM (Sousse, Tunisia), Rabeb MBAREK, Mohamed Aymen JAOUADI, Fatma BOUKADIDA, Majdi OMRI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #10976 - Liver Transplant In Code 0 Situation.
Liver Transplant In Code 0 Situation.

Spain is the country with the highest number of donors per million. In 31 years, in a population between 38.500.000 people in 1984 and 46.438.422 injanuary of 2016  there were more than 20000 liver transplants done .The etiology of hepatic insufficiency is  varied and related to viruses, toxins, drugs, ischemia ..The mortality associated with fulminant hepatic insufficiency is high and is due not only to hepatic failure, but also to the complications that affect the differents systems related :renal, respiratory.. Acute liver failure is the fourth cause of liver transplantation in Spain, after alcoholic cirrhosis, HCV-associated cirrhosis and hepatocellular carcinoma. That is 4.3% of the total of liver transplantation and up to 14% of these patients must be re-implanted.

We explain the case of a 19-year-old woman transferred from a county hospital in situation of Code Cero pending liver transplantation. Without a previous medical or surgical history, she presented one month before the entry flu-like symtoms with febrile sensation and prostration. She was valued in the emergency room and treated with empirical antibiotic therapy: clavulanic amoxicillin and subsequently azithromycin. She developed progressive worsening of the general state associated with mucocutaneous jaundice so she went to the hospital . At the moment of admission she was hemodynamically Stable , worsening level of consciousness with GSC of 13 .They performed blood tests with liver profile that showed hypoglycemia, total bilirubin 14.59 mg/dl,AST 1560 U/L,ALT 996 U/L ,Amonio in blood was 193 mEq/l. She also had coagulopathy. Patients with acute liver failure typically have prolonged prothrombin times and international normalized ratios because of a reduction in hepatic synthesis of clotting factors.In this case she had prothombin time of 26 sec with INR of 2.3 and factor V of 45% .This patient had no history of paracetamol or mushrooms intake. She was diagnosed of an acute liver failure due to an idiosyncratic reaction probably.They started with plasma transfusion, a central venous catheter was placed and infusion of intravenous glucose serum. Abdominal imaging and serology tests were performed for viruses (HBV, HCV, EBV and CMV).She was transferred to the  ICU. It was assessed according to the criteria of the King's College to enter into a list of national  liver transplants and contacted the Intensive Care Unit of the referral hospital to include the patient in Code 0 protocol. This classification means a national priority for a liver transplant due to acute fulminant hepatic failure. Initially according to the criteria of the King's Collegue was rejected inclusion in situation of code 0.It was assessed according to the Clichy criteria and presented neurological deterioration with a grade of encephalopathy that progressed to grade IV. Then she was included in a transplant list in a situation of code zero and 48 hours later a liver transplant was performed .


María Palma BENÍTEZ MORENO, Marta JIMÉNEZ PARRAS (SPAIN, Spain), María Teresa VALLE GIL, Eduardo ROSELL VERGARA
08:30 - 17:40 #10936 - Local acute phlegmonous gastritis: case report.
Local acute phlegmonous gastritis: case report.

Phlegmonous gastritis is a rare suppurative bacterial infection of the stomach that is often fatal if the diagnosis is delayed. We present a case of a 60-year-old woman complaining of fever, epigastrium pain, nausea, and vomiting. The medical history included laparoscopic cholecystectomy. Physical examination revealed increased sensitivity and tenderness at the epigastrium area. Laboratory test results showed neutrophilic leukocytosis, and increased CRP concentration. Abdominal ultrasound showed pyloric antrum wall thickened 24mm circularly and fluid-filled cavity in the interior wall. Computed tomography scans revealed thickened lower part of the stomach wall and perigastric infiltration. Upper gastrointestinal endoscopy showed suppurative gastric mucosa with extensive inflammation, incisions were made and pus began to diverge. Microbiologic examination of a gastric aspirate demonstrated gram-positive coccus Enterococcus faecium and gram-negative facultative anaerobic Klebsiella pneumoniae. Histopathologic examination revealed neutrophilic exudates. Clinical diagnosis was made of acute phlegmonous gastritis and a surgeon recommended conservative treatment. Next 10 days the patient was treated with intravenous antibiotic amoxiclav. Further investigations referred positive dynamic and full recovery.


Vilius VAITKUS, Renata ANDROSAITE (Vilnius, Lithuania), Vilma VAPSVAITE, Raliene KAROLINA
08:30 - 17:40 #11943 - Ludwig angina a nightmare for an emergency physician.
Ludwig angina a nightmare for an emergency physician.

We present the case of a 56 yars old male who was found collapsed in a hotel room. He was transfered by ambulance to the emergency department (ED) . On arrival he had an enlarged neck and stridor. GCS 14/15, HR 120, Blood pressure of 90/60 saturation of 78 and a respiratory rate of 23 . In terms of bloods marked metabolic acidosis ph 7.120 lactate of 9, white cell count 43000 and crp of 340. Anaesthesia team was informed and he was transfereed to theatre for an invasive airway protection. He was intubated with a ETT of 7 gas induction. CT scan of neck thorax abdomen and pelvis with contrast was performed and revealed a marked inflammation and soft tissue thickening within the neck anterior to the ET tube with an abcess formation anetrior to the ET tube just above the hyoid bone. Patinet was transfererd to an ENT service where the abcess was drain and a tracheotomy was performed . He was discharged home after 3 weeks . 

As emergency physicians we are all afrrayed of loosing an airway . Ludwing angina is one of the particular cases where a pattent airway can be obstructed in minutes if not maintained.


Octav CRISTIU (Duleek, Ireland), Ahmed JAMAL, Petrovici DANA
08:30 - 17:40 #10856 - Lumbar pain resistant to opioid treatment in a 33-year-old man, an initial symptom of Burkitt-type acute lymphoid leukemia in a patient with HIV not previously known.
Lumbar pain resistant to opioid treatment in a 33-year-old man, an initial symptom of Burkitt-type acute lymphoid leukemia in a patient with HIV not previously known.

Personal history
No allergies to medications. No toxic habits. No personal history of interest


Current disease: A 33-year-old man goes to the emergency department for a 3-week history of low back pain that has been resistant to analgesic treatment with opioids (fentanyl). During the interview he referred in the last 72 hours to a picture of polyadenopathies and feverish sd that relates to catarrhal picture. It does not present functional impotence nor loss of senility, control of sphincters. In perineal anesthesia.
Physical exploration:
- Good general condition, conscious and oriented eupneico low
- Head and neck: oropharyngeal muget, anterior cervical adenopathies, supraclavicular. Symmetrical pulses.
- Cardiopulmonary auscultation: Breathless rhythmic, preserved vesicular murmur
- Abdomen: soft and depressible without masses or megalias, negative blumberg, negative Murphy, fist negative renal perfusion
- Lower limbs: no edema, no signs of thrombosis, preserved pulses.


Supplementary tests:


Blood tests: Hb 11.5 mg / dcl, platelets 93,000, leukocytes 2,500 (800 neutrophils), TP 67%. Glucose 120mg / dl, creatinine 2.5mg / dl (FG 33) LDH 593 U / L PCR 218mg / l
Chest x-ray: normal cardiothoracic index. No signs of condensation, no pinching of costophrenic sinuses.
Given these findings, the patient is admitted to the internal medicine service to control renal function and to expand complementary tests.

During entrance the following tests are performed:
- CSF: negative immunophenotype for neoplastic cells.

- Nuclear magnetic resonance column: bone marrow infiltration lumbar and sacral vertebrae. Anterior epidural mass in L4-L5: S1

- Ultrasound of the abdomen: Hyperechogenic nodule of 7 mm in LHI suggestive of hemangioma. Rest without findings.

- TC TORAX / ABDOMEN / NECK: with the objective of multiple bilateral cervical lymphadenopathy, supraclavicular and axillary lymphadenopathy. Malignant lesions with poorly defined borders and homogenous contents in both hepatic lobes. Enlarged kidneys that pick up contrast irregularly. Multiple retroperitoneal adenopathies in the root of mesentery, iliac and inguinal chains.

- Bone marrow aspirate: Compatible with L3 acute lymphoblastic leukemia (FAB) / Burkitt NHL with 90% blastic cells

- HIV positive and negative serology for HCV, HBV (HBsAg and antiHBc negative, antiHBs positive), Sifilis, toxoplasma, CMV, HSV, EBV (negative IgM, positive IgG).

After confirmation of HIV diagnosis and proliferative syndrome, bone marrow biopsy is performed and antiretroviral therapy is initiated, as well as increased hydration in the presence of renal failure. Treatment with chemotherapy begins (BURKIMAB 13)

Conclusion:


Burkitt-type acute lymphocytic leukemia is more linked to immunocompromised patients, as in this case in which the patient was unaware of being a carrier of HIV. 
On the other hand before a picture of bone pain resistant to treatment accompanied by constitutional syndrome we must think of a lymphoproliferative syndrome


Rafael INFANTES RAMOS (Málaga, Spain), Cristina FERNANDEZ- FIGARES MONTES, Ivan VILLAR MENA, Manuel AGUILAR CASAS, Jose Ignacio VALERO ROLDAN, Maria Victoria ALARCON MORALES
08:30 - 17:40 #10948 - Lumbosciatic Syndrome, a current health problem to care for.
Lumbosciatic Syndrome, a current health problem to care for.

BACKGROUND

Lumbosciatic syndrome involves different manifestations from low back pain to sciatic nerve alteration. It represents a current health problem leading to complementary tests, medical resources and sick leaves, which have major economic impact.

It is a frequent pathology assessed at emergency departments (EP), where the system eases priority attention for those severer cases.

 

OBJECTIVES

Our aim is to know the current situation of this pathology at the Emergency Department of a Tertiary – care Hospital. We also want to analyse the profile of adults presenting to an EP setting with low back pain and its general management.

 

METHODS

An observational, descriptive, retrospective study was made with all patients older than 14 years old, which have been attended at the EP with diagnosis of lumbago pain or sciatica, during the period between January 1, 2016 and December 31, 2016.

Data for all patients were retrieved from the ED Information System database (PCH) and treated with SPSS v 15 program.

 

RESULTS

A total of 126.628 urgencies were attended at the EP during the study period; 2803 (2.21%) of the episodes met inclusion criteria (presented diagnosis of lumbago/ sciatica). Average age:  51 years old, 1463 women (52.2%) and 1339 men (47.8%). Over half of the patients presented a low priority level (54% in IV level and 37% in the V level of the Spanish Triage System). The discharged rate reached 95,7% (2684 of the patients). One hundred and eighteen patients were admitted, 49 of them (41,5%) to Neurology service, 37 (31,5%) to Neurosurgery, 26 (22%) to Rheumatology and 6 (5%) to other services.

 

CONCLUSIONS

1. Lumbosciatic syndrome is a usual presenting complaint attended at the Emergency Departments representing 2.21% of the medical assistances, though the priority – setting systems generates reassuring results as over ninety percent of them presents low priority level. Besides, it counts on a high rate of discharge (95,7%).

2. Our results expose that low back pain might be an overblown pathology at the EP. Practitioners and administrative manager should be aware of the potential impact; better planning management and collaboration protocols should be performed in order to facilitate the approach of this pathology in primary care.


Isabel PÉREZ PAÑART, Marta DEL PUEYO PARRA, Román ROYO HERNÁNDEZ, Victoria ORTIZ BESCÓS, Teresa ESCOLAR MARTÍNEZ DE BERGANZA (Zaragoza, Spain), Joaquín GÓMEZ BITRIÁN, Patricia ALBA ESTEBAN
08:30 - 17:40 #11890 - Main reasons for patients discontent in Emergency Department: do medical and paramedical staff have the same opinions ?
Main reasons for patients discontent in Emergency Department: do medical and paramedical staff have the same opinions ?

Emergency departments are subject to numerous injunctions as a result of a steady increase in the number of consultations. The number of complaints from individuals or patients associations tends to increase, and these relate to a variety of reasons. In order to become aware of the difficulties that patients may face and to start thinking about how to improve care, we wanted to know what were the reasons for patients' dissatisfaction, and whether their perceptions were different towards medical and non-medical staff.

Method:
Observational monocentric study by an anonymous computerized questionnaire in an emergency department (SAU) of an academic hospital. Questionnaire were addressed to all the medical and paramedical staff of the department. Each subject had to classify the main reasons for dissatisfaction of the patients on the subjects of communication, waiting times and material conditions. The ranking of the items was done through Borda count and the rankings were compared between physicians and paramedics.

Results
n = 78 (56% of ED staff, 46% of nurses, 38% of caregivers, 86% of health managers, 85% of physicians, 100% of residents). As far as communication is concerned, all the staff has the same classification and considers that the difficulties of communication between doctors and patients are the main cause of dissatisfaction. It comes after those between nursecaregivers and relatives and then the imposed separation of relatives and patients. In terms of waiting times, the first cause of dissatisfaction is waiting time before seeing a physician, then waiting until specialized opinion, then delay before imaging exams. Concerning the material conditions of patients’ reception: the staff is unanimous and places the difficulties of respect for privacy and confidentiality, than comes the problems of stretchers comfort and finally the absence of water or food. The classification was the same whether it was done by the medical or paramedical staff. 

Conclusion:
The medical and paramedical staff of an emergency department identifies the same causes of patient discontent. They place waiting time before seeing a doctor, issues of privacy, and difficulties in communicating between physicians and patients at the heart of patients' concerns. These items can be used to initiate multidisciplinary working groups to try to improve these points and improve patient care in emergency departments.

 


Carine GAUFFRIAUD (Paris), Anne-Laure FERAL-PIERSSENS, Jean-Baptiste MARCAULT, Philippe JUVIN
08:30 - 17:40 #10472 - MAINTENANCE FLUIDS IN THE EMERGENCY DEPARTMENT.
MAINTENANCE FLUIDS IN THE EMERGENCY DEPARTMENT.

Abstract is attached


Adrian CRAIG (University Hospitals of North Midlands NHS Trust, United Kingdom), Jonathan EASAW, Rose JORDAN
08:30 - 17:40 #11581 - Management and relief ot pain in Lorca´s Community Hospital Emergency department.
Management and relief ot pain in Lorca´s Community Hospital Emergency department.

Pain is the most common presenting complaint in the emergency department. Several studies have demonstrated that analgesia is usually underprescived.

OBJECTIVES: Previous studies have reported that pain is undertreated in the emergency department (ED). In this study, the authors determine the situation in Lorca´s Community Hospital.

METHODS: Prospective observational study of patients who were undergoing treatment for painful disorders in the ED. Before treatment for pain, patients were asked to complete a 100-mm visual analog scale (VAS) describing their pain. Demographic information and pain treatments administered were recorded. Patients completed a second pain VAS before discharge from the ED. 

RESULTS: 125 patients enrolled in the study. Of them, 61.9% received a pain medication while in the ED.  10% of the patients had higher VAS score at discharge than at arrival. 15% had the same VAS score. 55% had VAS score reduced less tha 50%, and only 20% had a VAS score reduced more than 50%.

CONCLUSIONS: Pain is greatly undertreated in Lorca´s Community Hospital 


Luis ESCOBAR Y ALVARO (Lorca, Spain), Joaquín JIMENEZ GONZALEZ, Isabel PERAL, María TRENZA PEÑAS, Isabel Beatriz MIRANDA NUÑEZ
08:30 - 17:40 #11462 - Management of anaphylaxis crisis in prehospital care.
Management of anaphylaxis crisis in prehospital care.

INTRODUCTION AND OBJECTIVES

Anaphylaxis crisis is a common emergencie that can occur in the pre-hospital setting. We present the results of a program to anticipate the management of this crisis from a Emergencies Call Center (ECC).

Methods

ALERT SCHOOL program was developed to anticipate the treatment of emergencies in children, including anphylaptic crisis, convulsions related or not with epillepsy, diabetes mellitus with hypoglycaemia crisis, and a miscellanous situations with the common risk to present a loss of consciousness. The teachers responsible of these children are trained in how to recognize a critically ill children, how to activate effectively the emergency system, and how to preserve and identify adequately the medication needed).

A retrospective analysis of the in-calls received by allergy with potential severe anaphylaptic crisis since the beginning of the Program was made , including the total of the patients registered, the number of emergency calls received, and the final destination of the patient. The possible solutions were: solved by phone (with or without direct intervention of the teachers), mobilization of sanitary resources and solved in situ, mobilization of a sanitary resource and solved in primary care center, admission to an Urgency Room (UR) of a Hospital Centre, or hospitalization. The results are presented as total number and percentage.

RESULTS

Between January of 2007 and June of 2016, 3313 patients were included in the Program. 1445 (43,62%) in relation with severe allergy, 574 (17,32%) epilepsy or febrile convulsions, 526 (15,88%) diabetes mellitus (hypoglycaemia), and the rest (768, 23,18%) included different illnesses with the common risk to present a loss of consciousness.

In the 9,5-year period in the ECC were received 35 emergency calls related to children previously diagnosed of allergy with potential severe anaphylaptic crisis. In 12 cases (34,29%) the situation was solved by phone in situ, in the other 23 cases a sanitary resource was required, in 7 cases (20,00%) the emergencie was solved in situ, in 6 (17,14%) in a primary care center, and 10 children (28,57%) were admitted to an urgency room of a Hospital Centre. None of the 35 patients required hospitalization.

DISCUSSION

Although anaphylaptic crisis in allergic children is a common concern of their parents, this is an uncommon situation (only 35 in-calls along 9,5 years of 1445 boys included). In addition, these situations can be anticipated; in fact up to 71,40% of the emergencies were solved in situ, and none of the children required hospitalization. Considering that the real emergencies (10, 28,57%) were identified and stabilised in situ before admitting them to the UR of a Hospital Centre, we can conclude that the program is also effective to distribute adequately the sanitary resources.

 


Emilia PEREZ MEIRIÑO, Luis SANCHEZ SANTOS (Santiago de Compostela (A Coruña), Spain), Antonio IGLESIAS VAZQUEZ, Carlos MIRAS BELLO, Manuel BERNARDEZ OTERO
08:30 - 17:40 #10498 - Management of anaphylaxis in Spain: pediatric emergency care providers’ knowledge.
Management of anaphylaxis in Spain: pediatric emergency care providers’ knowledge.

Background: Acute care providers must diagnose and treat patients with anaphylaxis. The objective of the study was to analyze the knowledge of the international recommendations for the management of anaphylaxis of the pediatric emergency departments’ providers in Spain.

Methods: We designed a web-based survey including providers (both attending and residents) from 7 Spanish pediatric emergency departments. To analyze the knowledge of the identification of anaphylaxis we used the diagnostic criteria given by the National Institute of Allergy and Infectious Disease and Food Allergy and the Food Allergy and Anaphylaxis Network (2005). To analyze the management we used the practical recommendations on the management of anaphylaxis published by the Joint Task Force on Practice Parameters (2014).

Results: A total of 425 physicians received the link and 337 (79.2%) fulfilled the survey (138 attending physicians, 76.6%; 199 resident physicians, 81.2%, n.s.). Globally, we received 5.729 responses to the different items, being correct 4.418 (77.1%), without significant differences between attendings (78.1%, 95% CI 71.2-85) and residents (76.4%, 95% CI 70.5-82.3). More than 90% of the providers identified correctly the anaphylaxis, except for two situations: not diagnosing anaphylaxis when reduced blood pressure is detected after exposure to a known allergen (69.7%, 95% CI 64.8-74.6) and misdiagnosis of anaphylaxis in patients with progressive urticarial with significant angioedema (65.9%, 95% CI 60.8-70.9). Nearly 100% identified the epinephrine as the first line treatment. Main failures related to the treatment were associated with the position of the patient (58.8%, 95% CI 53.5-54), the effect of medications to prevent the biphasic reaction (52.2%, 95% CI 46.9-57.5), the recommended time to observe patients (57%, 95% CI 51.7-62.3) and those related to the follow-up (28.8%, 95% CI 19.8-37.8). No significant differences were found between attendings and residents.

Conclusions: Even though the Spanish pediatric ED providers’ knowledge about the management of anaphylaxis is good, certain improvement areas are identified in both identification and management of these patients.


Mikel OLABARRI, González-Peris SEBASTIA, Paula VAZQUEZ, Aranzazu GONZÁLEZ-POSADA, Nuria SANZ, Ana VINUESA, Nuria DIEZ, Javier BENITO, Santiago MINTEGI (Bilbao, Spain)
08:30 - 17:40 #11349 - Management of carbon monoxide poisoning in the emergency department.
Management of carbon monoxide poisoning in the emergency department.

Introduction

Carbon monoxide poisoning (COP) is a common cause for emergency department (ED) admission especially during winter period in our country. It is a life-threatening medical emergency and treatment is based on oxygen therapy. The aim of our study was to study the epidemiological profile of patients admitted to ED for acute COP.

 

Methods

Prospective descriptive study over a period of four months. Inclusion of adult patients with recent CO exposure and blood carboxyhemoglobin (HbCO) dosage greater than 5% at admission. Collection of demographic, clinical and paraclinical data and therapeutic modalities.

 

Results

Inclusion of 125 patients. Mean age: 34 ± 13 years. Female predominance with a sex ratio=0.17. Eleven percent (n = 12) of women were pregnant. One hundred and ten patients (88%) had no medical history. It was a second episode of COP CO in three patients (2.4%). Sources of CO n(%): gas water heater 60(50), brazed 37(31) and gas heating 14(12). Poisoning was collective in 56% of cases (n = 70). Mean exposure duration to CO was 3 ± 3 hours with a mean consultation time of three hours. Symptoms n(%) :vomiting 49(41), palpitations 15(12.5), lipothymia 11(9), chest pain 7(6) and loss of consciousness 6(5). Oxygen saturation at room air was greater than 95% in all patients. All patients received minimal normobar oxygen therapy of six hours. Hyperbaric oxygen therapy was indicated in 22 patients (17%) but only given to seven patients due to lack of insurance cover. Four patients (3%) were hospitalized in intensive care unit.

 

Conclusion :

A young population with no medical history is mostly affected by COP. Preventive measures as well as raising awareness during the emergency visit and admission are compulsory to remedy this real public health problem.


Ines CHERMITI, Hedia GNENA (ben arous, Tunisia), Hanène GHAZALI, Ihsane HENANE, Sana TABIB, Monia NGACH, Mohamed MGUIDICHE, Sami SOUISSI
08:30 - 17:40 #11669 - Management of non traumatic acute abdominal pain in elderly patients in emergency department :.
Management of non traumatic acute abdominal pain in elderly patients in emergency department :.

Introduction:

The elderly population is rapidly increasing. Between 2000 and 2050, the proportion of the world's population over 60 will double from about 11% to 22%. Non-traumatic abdominal pain, particularly in elderly, is one of the most difficult problems to be resolved in terms of urgency. The management of acute abdominal pain in the elderly in the emergencies presents difficulties in diagnosis and evaluation due to atypical pain behaviors (anorexia, agitation, confusion, withdrawal, mutism, cognitive impairment)

Methods:

This is a 3-month prospective and descriptive review of all elderly patients (more than 65 years old ) who presented to the ED with non traumatic abdominal pain of less than one week's duration. Through this work, we propose to evaluate the management of acute abdominal pain in the elderly in the emergencies: reception and triage, diagnostic approach, complementary examinations, initial therapeutic treatment in emergencies and targeted orientation and to determine the incidences of both specific diagnosis and surgical diseases.

RESULTS:

A total of 79 patients were enrolled. 44, 3% was male and 55, 7% was female. The mean age was 71, 3 ± 4 years old . Majority of the patients (62%) presented with abdominal pain of less than 72 hour duration. The most common site of pain was the epigastric region (21.5%). Digestives signs were seen in 40.5% of patients .The common causes : renal colic (29.1%), acute pancreatitis (16.5%), acute Cholecystitis (13.8%), urinary tract infection (10.5%), acute appendicitis (7.6%) . More than half of patients (64.6%) were discharged from the ED and 37% of cases were managed by the emergency physicians. Surgical intervention was required in 25.8% of patients.

 Conclusion :

Acute abdominal pain in the elderly patient presents a significant and challenging problem. Diagnostic accuracy is lower, and mortality far higher, than in younger patients.

 


Ines GUERBOUJ, Rim HAMAMI (Tunis, Tunisia), Ghofrane BEN JRAD, Mehdi BELLASSOUED, Mounir HAGUI, Olfa DJEBBI, Bassem CHATBRI, Khaled LAMINE
08:30 - 17:40 #11188 - Management of Paediatric Asthma in the Emergency Department.
Management of Paediatric Asthma in the Emergency Department.

Background

The purpose of this research is to assess the management of children aged 5-17 years old who presented at the emergency department with moderate to severe asthma. We aim to compare the current standards of the Royal College of Emergency Medicine (2014) guidelines against our previous audit from 2014.
These standards include: 1) That oxygen is prescribed on arrival to maintain saturations > 94%; 2) Vital signs to and peak flow rate be taken within 15 minutes; 3) beta-2 agonist to be administered within 10 minutes; 4) Oral prednisolone or IV hydrocortisone administered prior to leaving the emergency department; 5) 90% of discharged patients to be prescribed oral prednisolone; 6) written discharge plan including follow up arrangements.
The initial audit highlighted that many standards were poorly complied with and such a re-audit was carried out in 2015-16.

Method

Data was collected from the paediatric emergency department in a district general hospital from 1st August 2015 to 21st November 2015. Children aged 5-17 years old presenting with moderate or severe asthma (as per Royal College of Emergency Medicine criteria) were included in the audit. Out of 50 initial cases, 35 met the inclusion criteria.  

Results

In comparison to our data from 2014. Admissions increased 9% (40% to 49%) and discharges decreased 9% (60% to 51%) in 2016. Oxygen was prescribed (to maintain saturations > 94%) in 100% of cases in both 2014 and 2016. The recording of vital sign measurements (respiratory rate, oxygen saturations, heart rate, temperature, responsiveness) within 15 minutes had decreased by 6% (72% to 66%). Peak expiratory flow rate measurement within 15 minutes had decreased 12% (18% to 6%).  Beta-2 agonist administration within 10 minutes slightly increased, but remained poor with only 29% compared to 28% in 2014. Steroid administration decreased by 13% (96% to 83%). Steroid prescription on discharge however had increased by 27% (from 67% in 2014 to 94% in 2016). Of all the admissions, only 67% cases were followed using the hospital’s acute asthma pathway documentation.

Discussion

It appears that the compliance to standards are slipping. There has been a decrease in all standards that require action within 15 minutes such as vital signs measurement (6%), peak flow rate (12%) and steroid administration (13%). This perhaps represents the pressures of a busier emergency department and poorer staffing levels. However the percentage of patients discharged on oral prednisolone massively increased by 27% to a total of 94% surpassing the standard of 90%. This is most likely due to departmental teaching on the matter.

Our recommendations are to educate staff in peak flow rate measurements and to include the measurements on the electronic triage system. We also advise to educate each rotation of new junior doctors on the treatment of asthma and the use of the asthma pathway which includes all guidance set by the royal college. We will re-audit in a further 2 years.


Sharif KAMAL (manchester, United Kingdom), Buston GEMMA, Zia MUHAMMAD
08:30 - 17:40 #10904 - Management of septic arthritis in the ED and proposal for a standard operating procedure.
Management of septic arthritis in the ED and proposal for a standard operating procedure.

Introduction

The presentation of a patient with a hot swollen joint is a common emergency with a lot of differential diagnosis. The most serious of these is septic arthritis (SA). Delayed or inadequate treatment can lead to irreversible joint destruction with subsequent disability. Diagnosis should be made rapidly and treatment started promptly. Joint aspiration and synovial fluid microbiological analysis are fundamental tools in the primary evaluation. The aim of the study was firstly to evaluate Emergency Department (ED) cares and secondly the proposal of a standard operating procedure (SOP) in order to homogenize practices.

Methods

We present here, a two-year (2014-2015) retrospective and monocentric study conducted in a French teaching hospital. During the study period, we included all adult patients with a supposed diagnosis of SA who presented to the ED. We collected and analyzed all clinical, biological, imaging, treatments and evolution data during the ED stay. A total of 107 patients with suspected SA have been included for analysis.

Results

In the study population, median age was 59 years (IQR: 44-76) and the sex-ratio was 1.1. Pain (65%) was the main symptom followed by edema (30%). The knee was the most punctured joint (83%) followed by the ankle (6%), hip (5%), elbow (4%) and others (shoulder, wrist and toes, 2%). More than half of the joint aspirations were performed by the ED physician (56.6%). Only a third (37%) of all patients had fever over 38°C. The final diagnosis was SA for 25 patients (23%) with only 11 microbiological confirmations, microcrystalline arthritis for 25 patients (23%), bursitis (11%), arthrosis (11%), post-traumatic hemarthrosis (16%), and other diagnosis (16%). Biological results showed higher leukocytosis (13058 vs 10257, p=0.007), higher C reactive pretein (152 vs 87, p=0.009) and lower eosinophils in the SA sub-group. Imaging was performed for 58% of all patients (mostly radiographics) and the studies were pathologic in 65% of cases. Antimicrobial therapy was given in the ED in 29% of all patients. Aminoglycosids were the most prescribed antibiotics mostly associated with penicillin M for a mean duration of 28 days. Surgical treatment was needed for 13 patients (12% of all patients but 32% of SA patients). Finally, 55% of patients were hospitalized for a mean duration of 11 days. The 1-month and 3-month mortality were respectively 2.3% and 4.6% (all in the non SA sub-group).

Conclusion

The management of suspected SA in our ED remains heterogeneous so we propose a SOP in order to improve daily practices. What is now clear is that SA is difficult to manage and in this circumstance sepsis should always be assumed until proven otherwise. The absence of a fever  cannot reliably exclude the diagnosis, nor can a negative synovial fluid culture. There is no gold standard for the diagnosis of SA, save that the overall judgement of an experienced physician has proven superior to any laboratory or radiological investigation.


Sébastien KIRSCH (Strasbourg), Philippe KAUFFMANN, Mickaël FORATO, Mihaela MIHALCEA-DANCIU, Elena Laura LEMAITRE, Sarah UGÉ, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11237 - Management of severe bleeding in patients treated with direct oral anticoagulants in a emergency department.
Management of severe bleeding in patients treated with direct oral anticoagulants in a emergency department.

Introduction

Three million people had received anticoagulant treatment in France in 2013 and 5000 fatal cases of accidents under anticoagulant treatment occur each year. People over 75 represent one third of the population in France and 20% have anticoagulant treatment for various causes

Methods

We conducted a retrospective, observational, monocentric study in an univesritary hospital. The primary outcome was the rate of the severe bleeding or haemorragic choc. The secondary outcome was to calculate the time necessary to administrate the antidote and the rate of mortality due of a severe bleeding.

Results

541 patients over the age of 75 consulted in the emergency department during the study period. Of these, 169 patients (31,23%) were under anticoagulant therapy. Two patients were dead (1,83%) due to intracranial bleeding and two patients (1,83%) have been embolizated. Eighteen patients (10,65%) had an INR (international normalized ratio) greater than 3. All patients who were an INR greater than 3 (n=18) has been hospitalised at least 24 hours for monitoring. Of them, 17 (10,05%) had an hemoglobin lower than 10g/dl, 11(6,5%) a systolic pressure lower than 100mmHg and 10 (5,91%) an active bleeding. Twenty patients (7,1%) were treated by vitamine K, 9 (5,32%) by vitamine K and prothrombin complex concentrates. Ten patients (5,91%) have been transfused. Twenty patiets (7,1%) had severe bleeding or haemorragic choc. All patients was examinated rapidely and all of them received the antidote in less than 60 minutes. 

Conclusion

The aging of the population is felt in the emergency services, which welcomes more and more elderly patients. The loss of autonomy of these patients leads to an increase in the number of falls. If in most cases minor lesions such as bruises, wounds with no major bleeding occur, 10% of deaths are related to haemorrhages under oral anticoagulant therapy. The benefit-risk balance of anticoagulant therapy should be reassessed more often, especially in elderly fallers. In the emergency room, all patients with an INR grater than 3 have been treated by antidote in less than 60 minutes. The transfusion was administrated between 1 and 2 hours.  


Laura DASCALU (STRASBOURG), Pierrick LE BORGNE, Sarah UGE, Celine RENFER, Bilbault PASCAL
08:30 - 17:40 #11231 - Management of severe hypoglycaemia in pre-hospital care.
Management of severe hypoglycaemia in pre-hospital care.

Background:

Severe hypoglycemia is the main limiting factor in achieving optimal control of diabetes. This serious and frequent complication is a real problem in the management of diabetic patients because of its medical consequences, therapeutic repercussions and economic impact. The aim of our work is to study the clinical and therapeutic characteristics of patients presenting hypoglycemia in pre-hospital care.

Methods:

This is a retrospective descriptive study conducted over a ten-month period including all medical records of our emergency call center with the final diagnosis was hypoglycemia. The demographic, clinical and therapeutic data were recorded and analyzed using the SPSS 20.0 software.

Results:

A total of 97 patients were included (1.28% of all calls and 3.65% of primary interventions during the study period). Calls came from patients' homes in 81.6% of cases, care institution in 8.2% of cases and a public place in 8.2% of cases. The average age was 61.7 years and the sex ratio was 1.26. Seventy-seven patients were insulin-dependent diabetics, 13 patients had oral anti-diabetic drugs (2 of which had sulfonamides) and 7 patients had no diabetes (including one alcoholic patient and one hepatic insufficiency). Initial capillary blood glucose levels averaged 0.33 g/L with extremes ranging from 0.11 g/L to 0.7g/L. The most common clinical signs were neurological disorders (altered consciousness in 91.8% of cases and localization signs in 2.1% of cases) .Three patients were sweating and two had hypotension and tachycardia .

The treatment was administered intravenously in 61 patients and the dose administered in grams averaged 7.69 g with extremes ranging from 3 to 15 g.

After therapeutic management, post-correction capillary glycaemias were 1.23 g/l with extremes ranging from 0.72 g/L to 3 g/L.

Preventive measures were only carried out in 16 patients, ie 16.5% (taking oral sugar in 9 patients, consulting their doctor in 4 patients and decreasing insulin doses in 3 patients ). Seventy-four patients were left at home after medical intervention.

Discussion:

Severe hypoglycaemia can be fatal and often cause significant physical and psychosocial morbidity, especially in the case of insulin therapy, but also when treated with sulphonamides.

Due to the potential severity of this iatrogenic complication of diabetes in terms of medical complications and socio-economic impact, preventive actions must be undertaken on a large scale. Thus, reconciling the need for a good balance of diabetes by minimizing the risk of repeated hypoglycaemia is possible by patients' education relative to their lifestyle, their treatment and the recognition of the signs of hypoglycemia and the caregivers' education in terms of choice of treatment modalities, identification of the causes and risk factors of hypoglycaemia, adaptation of the objectives and communication with the patient.


Hajer KRAIEM (Sousse, Tunisia), Mohamed Aymen JAOUADI, Rabeb MBAREK, Nizar NAOUAR, Majdi OMRI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11232 - Management of severe hypoglycaemia in pre-hospital care.
Management of severe hypoglycaemia in pre-hospital care.

Background:

Severe hypoglycemia is the main limiting factor in achieving optimal control of diabetes. This serious and frequent complication is a real problem in the management of diabetic patients because of its medical consequences, therapeutic repercussions and economic impact. The aim of our work is to study the clinical and therapeutic characteristics of patients presenting hypoglycemia in pre-hospital care.

Methods:

This is a retrospective descriptive study conducted over a ten-month period including all medical records of our emergency call center with the final diagnosis was hypoglycemia. The demographic, clinical and therapeutic data were recorded and analyzed using the SPSS 20.0 software.

Results:

A total of 97 patients were included (1.28% of all calls and 3.65% of primary interventions during the study period). Calls came from patients' homes in 81.6% of cases, care institution in 8.2% of cases and a public place in 8.2% of cases. The average age was 61.7 years and the sex ratio was 1.26. Seventy-seven patients were insulin-dependent diabetics, 13 patients had oral anti-diabetic drugs (2 of which had sulfonamides) and 7 patients had no diabetes (including one alcoholic patient and one hepatic insufficiency). Initial capillary blood glucose levels averaged 0.33 g/L with extremes ranging from 0.11 g/L to 0.7g/L. The most common clinical signs were neurological disorders (altered consciousness in 91.8% of cases and localization signs in 2.1% of cases) .Three patients were sweating and two had hypotension and tachycardia .

The treatment was administered intravenously in 61 patients and the dose administered in grams averaged 7.69 g with extremes ranging from 3 to 15 g.

After therapeutic management, post-correction capillary glycaemias were 1.23 g/l with extremes ranging from 0.72 g/L to 3 g/L.

Preventive measures were only carried out in 16 patients, ie 16.5% (taking oral sugar in 9 patients, consulting their doctor in 4 patients and decreasing insulin doses in 3 patients ). Seventy-four patients were left at home after medical intervention.

Discussion:

Severe hypoglycaemia can be fatal and often cause significant physical and psychosocial morbidity, especially in the case of insulin therapy, but also when treated with sulphonamides.

Due to the potential severity of this iatrogenic complication of diabetes in terms of medical complications and socio-economic impact, preventive actions must be undertaken on a large scale. Thus, reconciling the need for a good balance of diabetes by minimizing the risk of repeated hypoglycaemia is possible by patients' education relative to their lifestyle, their treatment and the recognition of the signs of hypoglycemia and the caregivers' education in terms of choice of treatment modalities, identification of the causes and risk factors of hypoglycaemia, adaptation of the objectives and communication with the patient.


Hajer KRAIEM (Sousse, Tunisia), Mohamed Aymen JAOUADI, Rabeb MBAREK, Nizar NAOUAR, Majdi OMRI, Mounir NAIJA, Naoufel CHEBILI
08:30 - 17:40 #11520 - Management of spontaneous soft-tissue hemorrhage secondary to anticoagulant therapy: a prospective study of an interventional protocol.
Management of spontaneous soft-tissue hemorrhage secondary to anticoagulant therapy: a prospective study of an interventional protocol.

Study objective: Patients receiving heparin, warfarin or direct anti-coagulant who experience severe spontaneous soft-tissue hemorrhage (SSTH) may have a life-threating condition and the optimal management is unclear. The purpose of this study is to report a monocentric experience of an interventional protocol.

Methods: In this prospective case series, we enrolled consecutive patients with SSTH secondary to anticoagulation therapy diagnosed by appropriate computed tomography scan. We implemented a structured clinical pathway, including aggressive resuscitation, reversal of coagulopathy, interventional radiology procedures by transcatheter embolization (TE) and clinical and laboratory observation.

Results: We enrolled 54 patients. All patients underwent observation and were treated with blood transfusions and hemostatic therapy using vitamin K and/or coagulation factor concentrates, when indicated. Angiography was done in 36 patients: it revealed the bleeding site in 24 cases and a TE was performed (44% of all patients). Bleeding stopped in 23 of these 24 patients. In two patients, whose embolization was unsuccessful, the control of the bleeding was obtained with a second TE. Two patients died: one because of hemorrhagic shock and one because of septic shock associated.

Conclusion: A structured clinical pathway, including TE seems to be an effective and safe method to manage the patients with SSTH secondary to anticoagulant treatment.


Vincenzo MENDITTO, Sirio LOMBARDI (Ancona, Italy), Francesca FULGENZI, Armando GABRIELLI, Cinzia MINCARELLI, Anna DIMITRIADOU, Giovanni POMPONIO, Aldo SALVI, Roberto CANDELARI
08:30 - 17:40 #11932 - Management of vitamin k antagonists overdose at the emergency department: about 123 cases.
Management of vitamin k antagonists overdose at the emergency department: about 123 cases.

Introduction:

Oral anticoagulation is widely used to prevent thrombotic events. Vitamin k antagonist (VKA) is the only oral anticoagulation currently available in our country. VKA overdose can be asymptomatic or associated to bleeding. It is a serious situation leading to complications and even death. Management is codified and based on guidelines. In our emergency department (ED), the use of the guidelines of the French National Authority for Health is commonly accepted.

The aim of our study was to evaluate the management of VKA overdose patients admitted to the ED.

Methods

Retrospective observational study over 2 years. Inclusion of adult patients admitted to the ED for VKA overdose. Both asymptomatic and symptomatic overdose patients were included. Analysis of

Results:

Inclusion of 123 patients. Mean age: 66 +/- 11 years. There was not gender predominance (Sex-ratio = 1). Indications of VKA n(%) : atrial fibrillation 76(62), valvular diseases  24(19), pulmonary embolism 5(4), deep venous thrombosis 4(3). Comorbidities n(%): hypertension 68(55),diabetes 48(39) , cardiac failure 9(7), renal failure 7(6) and ischemic stroke 11(9). Five patients (4%) had a history of VKA overdose with major bleeding. Chief complaint n(%): external bleeding 33(26), ecchymosis 8(6), neurological signs 5(4) and systematic monitoring 47(38). Ten patients (8%) were haemodinamically instable with systolic arterial pressure less than 90mmHg. International normalized ratio (INR) was out the measuring range in 21% of cases (n=26). Vitamine K was prescribed in 87 patients (70%). Four patients had prothrombin complex concentrate. Two patients required vasoactives drugs, transfusion and urgent haemostatic interventions. Only 24 patients (19%) had early discharge from the ED within 6 hours of admission. Causes of overdose n(%) : drug interactions 15(12), lack of INR monitoring 35(28), dosage error 22(18) and recent change doage 17(14). VKA were definitively stopped in 14 patients (11%).

 

Conclusion:

VKA overdose is a frequent cause of admission in the ED. Our results demonstrated that prevention by awareness raising is the most important way of avoiding such situation.


Ines CHERMITI, Ihsane HENANE (La gazelle, Tunisia), Hanène GHAZALI, Hedia GNENA, Sana TABIB, Najla EL HANI, Moez MOUGAIDA, Sami SOUISSI
08:30 - 17:40 #11984 - Managing Hypoglycaemic crisis in Fructose 1,6 Bisphosphatase Deficiency.
Managing Hypoglycaemic crisis in Fructose 1,6 Bisphosphatase Deficiency.

14 year old Male, PC Know FBPase deficiency, discharged  3/7 from hospital.Came in with Poor oral intake;Vomiting;Hypoglycaemia

HPC- Patient was bought in by ambulance after having episodes of vomiting for the last 3 days. Was previous an inpatient and was discharged 3 days ago after a viral illness.

Since then has not been eating and hypostop not helping. No fevers and passing urine.

Drowsy this morning

PMH

Fructose 1,6  biphsophatase deficiency – one of a twin, who is also effected

Brother is also affected

Antenal 33/40 SVD

Form of cerebral palsy

Background

•Patient with deficiency of this enzyme cannot produce glucose from these substrates and cannot increase blood glucose levels in hypoglycaemic state.
•Children given fructose, leads to build up on of FDP  in the liver preventing gluconeogensis too.
Learning points
1.Awareness of the BIMDG guidelines in managing patient with rare metabolic diseases
2.Practise in calculation fluids ( BIMDG website has calculation and wasy to reconstitute fluids)
3.Establishment for personalised protocols to be keep and updated in ED Paediatric department for patient comeing in with emtabolic diseases.

Irfan ULLAH (London, United Kingdom)
08:30 - 17:40 #11202 - Managing low risk chest pain in an ambulatory emergency care unit.
Managing low risk chest pain in an ambulatory emergency care unit.

Background: Chest pain is a frequent cause of attendance to the emergency department. If ACS is to be excluded, current guidance recommends use of high-sensitivity troponin assays at presentation and then at 3 hours. This raises issues with 4 hour targets as patients are unlikely to have been fully assessed and had blood results back before this length of time has elapsed. They can be left in the waiting room unsupervised, or can occupy a cubicle space in a crowded emergency department for the duration. We wanted to see if we could safely manage appropriately selected patients in an ambulatory care setting – where the 4 hour target does not apply, they are observed, but do not take up a cubicle unnecessarily for several hours.

Methods: To do this we obtained data from the ambulatory care unit patient logbook over a one month period. All patients who presented with chest pain were then identified. Searched electronic case notes and history of blood tests to identify those that met low risk chest pain protocol. Categorised these patients into groups according to positive or negative troponin results.

Results: A total of 743 patients attended the ambulatory care unit in July 2016. Of these, 124 (16.7%) were identified as a chest pain presentation – the largest single patient group. Twenty-eight patients (29.7%) had two negative troponin tests. Sixty-one (64.9%) had a single negative troponin. Five patients (5.3%) had positive troponins and were referred for admission. Twenty-three patients were deemed not to require troponin tests as pain was attributable to another condition. Seven patients had incomplete records but were known to be discharged home.

Discussion: Chest pain presentations made up the biggest patient cohort admitted to our ambulatory care unit. Over a one month period, 5% of these patients were diagnosed with ACS. 89 patients were discharged home following assessment and blood tests. In the past, these patients would typically have been admitted for 12 hour troponin levels, or occupied an emergency department cubicle. We found that use of a high-sensitivity troponin assay with early rule out protocols to manage chest pain presentations in the ED can be safely achieved in an ambulatory care setting.


Mark GUEST (Liverpool, United Kingdom), Dan MULHOLLAND, Emily HARGREAVES, Peggy MACHIN
08:30 - 17:40 #11090 - Marathon runner survived from sudden cardiac arrest. A case report.
Marathon runner survived from sudden cardiac arrest. A case report.

Participation in long distance running races, like marathon or half-marathon has increased worldwide. Although the overall risk of sudden cardiac death among marathon runners is relative low, the race related cardiac arrest grows each year over the past decade in absolute number, due to the increase in participation, while the debate about the extent of  pre-participation screening for asymptomatic adults still raises concerns. This case report is about a long distance runner, 41-years old, who collapsed at the finishing line of the Athens Classic Marathon. He had no known cardiovascular risk factors and he reported carried out the standard pre-race examination consisted in personal and family history, physical examination and ECG. It was reported that the patient presented chest pain during the race, that ignored. The cardiac arrest was witnessed by an advanced cardiac life support team that immediately started advanced cardiopulmonary resuscitation, as the patient presented ventricular fibrillation. The patient was admitted to the emergency department, where he was intubated. The 12-lead ECG showed sinus rhythm, RBBB and q wave in V₁-V₄, the arterial blood analysis revealed metabolic acidosis and the echocardiogram indicated moderately decreased left ventricular systolic function with hypokinesis of the anterior wall, the septal wall and the apex of the left ventricle. He was admitted to the coronary unit after the patient was sent for coronary angiography. The coronary angiography revealed ostial thrombi in both the left anterior descending artery and the ramus intermedius, but without causing significant flow obstruction (TIMI flow III). Blood exams revealed high levels of high sensitive Troponin-I and normal serum electrolytes. Conservative treatment was followed and the patient received fondaparinux and dual antiplatelet therapy. On third day of hospitalization he was extubated and coronary angiography was repeated that showed significant reduction of thrombus burden. The patient recovered and he was discharged home after 10 days of hospitalization. Marathon is a potentially hazardous endurance sport. In fact, ischemic heart disease is the predominant cause of cardiac arrest and death among athletes over 35 years old. It seems that during the race, demand ischemia due to an imbalance between oxygen demand and supply, combined with the increased risk of atherothrombosis due to inflammation, can lead to plaque instability, thrombotic occlusion and ischemia induced malignant arrhythmias. Although the patient performed the standard pre-race examination, he experienced a serious life threatening event. Although cost is a big issue, we need to consider if pre-participation screening must include further examination, like exercise testing in order to identify asymptomatic patients at high risk, including middle-aged and older men running at the marathon and prevent cardiac arrest and sudden cardiac death.


Georgios TSITSINAKIS (ATHENS, Greece), Christina ZOTIKA, Sofia PAPPA, Panagiotis KOUTSOURADIS, Panagiotis PATSAOURAS, Demetrios PYRROS, Vlassios PYRGAKIS
08:30 - 17:40 #10084 - Mass casualty disaster simulations in hospitals: a waste of money?
Mass casualty disaster simulations in hospitals: a waste of money?

Title:Quality of evaluation of disaster-exercises in Dutch hospitals. 

Introduction. In the Netherlands hospitals are legally required to prepare for disasters. Roughly 10 million euro has been spent in the last 9 years. At this time, the most common method to prepare is through simulations. In this study an attempt is made to assess the quality of the evaluations of these simulations and to find a methodology that can assess if such simulations improve the preparedness of hospitals.

Methodology:

165 critical remarks from 16 sets evaluation-reports (2 separate years for each hospital) on Mass Casualty Incident exercises for the strategic crisis team (SCT) in Dutch hospitals were scored against a list of 15 evaluation-categories and each evaluation-report was scored on 4 aspects of the evaluation-design.

Results:  66% clearly stated the goal of the exercise, a mere 15% used a template for performance indicators to evaluate the team and in 18% of the reports could the critical remarks all be linked to the goal of the exercise.

Comparing the number of remarks between the first and the last exercise in evaluation-themes , 8 of the 14 themes showes no decrease of the number of remarks. Although speculative, this suggest no significant improvement regarding the preparedness of these categories. 10 of the 16 sets of reports studied show 1 or more remarks that was formulated in almost the exact same wording in both reports. This underlines that teams tend to make the exact same mistake and therefore contradicts the learning effect of the exercises.

Conclusions:This study, based on the assumption that the number of critical remarks would decrease as result of the learning effect of a disaster simulations, suggests that there is no or limited learning effect for the SCT. At the same time, the study showed a large variety in evaluation methodology

The findings of this study suggests the need for a clear and univocal evaluation system for hospital simulation exercises, in order to compare disaster preparedness performances over time.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 


Marlous VERHEUL (utrecht, The Netherlands), Joost BIERENS, Ralf BEERENS, Willy Anne VAN STIPHOUT, Visser BEA
08:30 - 17:40 #11699 - Massage – Massacre in Polycythemia Vera.
Massage – Massacre in Polycythemia Vera.

                                                                                                                                                        Massage – Massacre in Polycythemia Vera

Introduction:  Polycythemia Vera (PV) is a hyper-coagulable state in which the affected individual is prone for thrombus formation and its complication often. Any PV patient presenting with musculo skeletal pain, a chance of underlying thrombus should always be considered.

Case Description: A 70 year old lady presented to Emergency Department (ED) with sudden onset of painful diffuse swelling of left side neck, shoulder and arm since 4-5 days. She was a known case of PV, on regular medication for the same. Prior to this clinical presentation she underwent massage for left sided cervical pain. Blood work up suggestive of coagulopathy. CT Thorax with contrast showed thrombotic occlusion of left subclavian, IJV, branchiocephalic vein with adjacent stranding, significant splenomegaly. She was diagnosed as left Internal jugular vein(IJV), subclavian vein and axillary vein thrombosis. Admitted in ICU under vascular surgeon, Hematologist consultation was sought. Treated with heparin Infusion.  After 6 days of hospital stay she was discharged home.

DISCUSSION: PV (erythremia, primary polycythemia)  is a myeloproliferative disorder leading to hypercoagulable state.Which is usually associated with a gene mutation called JAK2V617F but cause is unknown. Thromboses in PV patients are very frequent as a result of disruption of hemostatic mechanisms because of an increased level of RBCs and an elevation of platelet count. Especially in this patient one more attributing factor is endothelial injury due to massage. A massage can even be fatal in patient with PV. Better to avoid massage in a patient with PV.

 


Ramkumar SWAMINATHANE (Qatar, Qatar), Gopikrishna DUVVADA, Suresh THIRUMOORTHY KUMAR
08:30 - 17:40 #11922 - Massive haemoperitoneum associated with ectopic pregnancy.
Massive haemoperitoneum associated with ectopic pregnancy.

Case report

39-year-old woman with no past medical history of interest, and last period date three weeks ago, was attended because of dizziness and loss of consciousness of seconds, with abdominal pain and nausea. No other symptoms.
Exploration: the patient was hemodynamically stable but had a distended abdomen that was painful to the palpation, and had, as well, a diffuse form in hypogastrium, with defense at that level.
After checking bloods, there was a high leukocytosis with neutrophilia and anemia with value of hemoglobin of 8.3 g / dl, with no other problems. Because of the high level of pain, an abdomen CT scan was performed, which shown a moderate-severe amount of perihepatic free high density fluid , and perisplenic and pelvic location, that suggests of large hemoperitoneum, with a periuterine and pelvic hematoma. It shown as well, a discreetly enlarged uterine cavity, and at the same time an enlarged cystic image in the left ovary. Gestation test was requested, with positive result, and Chorionic Gonadotropin Hormone (B-hCG) with a value of 2247 mUI/ml.
The patient remainded under observation, and two red blood cells units were transfused. The patient was checking by the Gynecology team, and after that, was operated. The surgery consisted in a right salpinguectomy and an hemoperitoneum evacuation.

Conclusions

Global ectopic pregnancy incidence is 1-2% with an increase over the last few years. Its exact aetiology is unknown despite a high relationship with pelvic inflammatory disease. This type of pregnancy complication is associated with a greater risk of subsequent infertility. Its early diagnosis by determination of B-hCG levels and transvaginal ultrasound is essential to prevent complications that could put maternal health at risk, with a mortality between 2-5%, mainly due to haemorrhage. The new therapeutic advances have led to less invasive and aggressive techniques for its treatment and diagnosis.


Maria Del Carmen RODRIGUEZ CASIMIRO, Enrique CARO VAZQUEZ (MALAGA, Spain), Carmen A YAGO CALDERON, Juan A RIVERO GUERRERO, Valentina MORELL JIMENEZ
08:30 - 17:40 #11003 - Massive hydroxychloroquine overdose.
Massive hydroxychloroquine overdose.

Hydroxychloroquine is used to treat malaria. Hydroxychloroquine overdose is rare, but cases of severe and lethal complication have been reported intermittently. We report a case of massive amount overdose which produce sustained refractory ventricular tachycardia and heart failure.

31-year old, female patient with rheumatoid arthritis presented in the ED with decreased mental status.  Glasgow coma scale was 12 points, blood pressure was 60/20 mmHg, heart rate 60 per minute, respiratory rate 20 per minutes and body temperature 36.8 °C. She had ingested alcohol and rheumatoid arthritis medication: 12 g of hydroxychloroquine sulfate. The first 12-leads electrocardiogram on patient's arrival showed sinus bradycardia (58/min) with wide QRS complex, premature atrial contractions. Corrected QT interval was 437 msec. Blood gas analysis showed pH 7.373, PCO2 33.6 mmHg, PO2 487.6 mm Hg, bicarbonate 19.8 mmol/L , lactate 2.4 mmol/L with oxygen 10 L/min via mask. Hypotension was stabilized by intravenous normal saline and norepinephrine administration. Then a nasogastric tube was placed, activated charcoal was given. Intravenous lipid emulsion and bicarbonate were used according to literature search.Initial serum electrolytes, liver function test, blood nitrogen, creatinine, complete blood count, troponin-T were within normal except mild hypoglycemia (68 mg/dl). Two hours after presentation, potassium dropped to 2.8 mEq/L and intravenous potassium supplement was started.On arrival five hours later, she had short runs of ventricular tachycardia with chest discomfort and dyspnea, then a monomorphic pulseless VT was developed, which was converted by defibrillation with 150J. Twenty two time recurrence of VT in 12 hours was converted by synchronized cardioversion (100J). Recurrent VT didn’t respond to amiodarone. Her dyspnea deteriorated and pulmonary edema was found on chest radiography. Echocardiography showed akinesis at basal to mid inferoseptal, anteroseptal and anterior wall associated with decreased LV systolic function (EF 37.7%). Endotracheal intubation and mechanical ventilation were applied and high-dose diazepam infusion was continued for 2 days (2 mg/kg IV over 30 minutes followed by 2 mg/kg/d). Recurrence of VT gradually decreased. On day 4, mechanical ventilation was weaned. A psychiatric assessment was carried out and she was discharged home 9 days post-ingestion with no residual complications of her overdose.

Sodium and potassium channel blockade are the proposed primary mechanisms of cardiovascular toxicity, and hypokalemia is extremely common in hydroxychloroquine overdose. Cardiovascular manifestations include QRS prologation, AV block, ST and T wave depression, increased U waves, and QT interval prolongation. Life-threatening ventricular arrhythmia can occur rapidly following ingestion.


Byung Hak SO (Suwon, Republic of Korea)
08:30 - 17:40 #11791 - Massive Pulmonary Thromboembolism.
Massive Pulmonary Thromboembolism.

 

Woman 82 years without drug allergies, no history of interest, comes to emergencies from primary care, by cough of more than 10 days of evolution, not improved despite oral antibiotic therapy, increasing its usual to make medium-sized effort dyspnea.

Constants: AP: 124/82 mm[Hg] CF: 94 l/min Oxygen Saturation: 94 % Tª: 37,2ºC

Physical examination: no engorgement jugular. General condition good. Eupneica.

• Rhythmic heart sounds, without murmurs.

• Vesicular murmur preserved with fine crackling minimum crepitants.

• Soft abdomen, depressible without visceromegalias, no signs of peritoneal irritation.

• Lower limb without edema. No signs of DVT.

Complementary tests:

•  EKG: sinusal rhythm. negative T waves in V1-V4.

• RX thorax: index preserved cardiothoracic, triangular peripheral image * in LSI. No evidence of condensation.

• Analysis: leukocytes 14,400 86% neutrophils. Pro BNP 5185, troponin Ths 40.8 PCR 25.3.

Before these findings, asked again to the patient (asymptomatic and with basal O2 saturation in 95%), and adds a slight left pleuritic pain to anamnesis in the past two days, increasing with respiratory movements. With all of this, request CT of pulmonary arteries: observed numerous defects of repletion intravascular bilateral multiple pulmonary artery thromboembolism pulmonary (PE) extensive in segmental arteries of right upper lobe, the middle lobe artery and its segmental artery of the right lower lobe with extension to three segmental-compatible. In the left lung is also defective in repletion in several segmental arteries of the left upper lobe, with * small parenchymal associated infarction. Signs of overload in the right cardiac cavities.

The patient entered in internal medicine by presenting good evolution of the episode.

Conclusions

The PE is one of the leading causes of death in the general population (third cause of death in hospital). It is estimated that its incidence is one case per 1,000 people per year.

The symptomatology is highly variable, non-specific and even absent in many cases, therefore, complementary examinations casual findings, must make us suspect this disease:

- 80% of patients with PE without cardiopulmonary pathology present abnormal chest x-ray (dilation of right cavities or pulmonary infarction, * Hampton hump).

- Electrocardiogram. Useful to assess signs of associated pulmonary hypertension and right overload. They show a sensitivity of 23.5% and a specificity of 97.7%.


Marta CELORRIO SAN MIGUEL (VA, Spain), Carlos DEL POZO VEGAS, Jaldún CHEHAYEB MORÁN, Enrique Antonio SERRANO LACOUTURE, Susana DE FRANCISCO ANDRÉS, Sonia DEL AMO DIEGO, Armen HAMBARDZUMYAN
08:30 - 17:40 #11032 - Maxillofacial injuries in elderly: brief synopsis of their occurrence, etiology and sociodemographic characteristics in emergency units in Chile (Fonis SA15l20196 project).
Maxillofacial injuries in elderly: brief synopsis of their occurrence, etiology and sociodemographic characteristics in emergency units in Chile (Fonis SA15l20196 project).

INTRODUCTION
In Chile, 1 in 10 people is an older adult. This increase in life expectancy has resulted in profound changes in morbidity and mortality profiles with impact on events such as facial trauma. For instance, it is known that the case series of this type of trauma has evolved from a condition occurring mainly in urban youth to older age groups that progressively appear in greater proportion in emergency consultations. To go in depth in the characteristics of this population is the objective of this study.

 

OBJECTIVE
Our purpose was to explore clinic and sociodemographic characteristics of elderly consultants population for maxillofacial trauma in three high complexity Hospital Emergency Units in Chile and to characterize the patterns of facial lesions and their etiology.

 

METHODS

This study is based on the complete case series of three high complexity Hospital Emergency Units in the two most populated urban areas of Chile: Santiago and Valparaíso, with older adults proportions between 11 and 13%. Sociodemographic and clinical-related data were extracted from 24-hour Emergency Units records of each center, all including maxillofacial expertise. A case definition was made: primary maxillofacial trauma-related consultations in over 60 years, from May 1, 2016 to April 30, 2017. Diagnosis and coding were performed by maxillofacial surgeons during study period. Summary measures analyses were made by establishing differences by Chi Square and non-paired Wilcoxon. Data were exploited in Microsoft Excel and Stata 14.0® statistical softwares. The project was approved by the Ethical Scientific Committees of each participating center and the Faculty of Dentistry in charge of the study.

 

RESULTS
Of total number of Emergency consultations during the study period, about 20% corresponded to older adults with variability among centers. The highest numbers were presented on Mondays and Sundays. A predominance of women was observed, being the fall the most frequent cause with differences by sex (p <0.05). The injury profile included mainly contusions (soft tissue) and fractures in the middle third (hard tissue, especially nasal fractures).

 

CONCLUSIONS
The adult population maxillofacial trauma profile at Emergency Units of study centers is composed mainly by women whose cause of consultation is the fall, consistent with the type of injury observed. The variability in the total proportion of over 60 years population in each center and the proportion of males seems to be associated with different stages of ageing of each locality and their degree of development.


Fabiola WERLINGER (Santiago, Chile), Valentina DUARTE, Marcelo VILLALÓN, Eugenio BÁEZ, Joaquín JARAMILLO, Raúl ACEVEDO, Leonardo AGUILAR, Rodrigo AGUILERA, Diego ALCOCER, Mario ARRIOLA, Oscar BADILLO, Rene BRIONES, Hugo COOPER, Marcela DEL RÍO, Cristian DÍAZ, Roberto GARCÍA, Rodrigo GOYA, Jaime HENRÍQUEZ, Mauricio HERRERA, Felipe MERCHAN, Marco NASI, Roberto OSBEN, Juan PASTRIÁN, Roberto REQUENA, Alejandro RIVERA, Santiago RIVIELLO, Juan ROJAS, Constanza VIDAL, Gastón RODRÍGUEZ, Esteban ARROYO, Juan CORTÉS
08:30 - 17:40 #11023 - Measurement of B-type natriuretic peptide using Minicare I-20 : development of a new Point-of-Care assay for blood and plasma samples.
Measurement of B-type natriuretic peptide using Minicare I-20 : development of a new Point-of-Care assay for blood and plasma samples.

To support rapid diagnosis in the emergency setting, Philips has developed a cTnI assayfor its point-of-care analyzer, the Philips Minicare I-20, allowing test results in less than 10 minutes in a near-patient setting. Philips is currently developing a B-type natriuretic peptide (BNP) assay to expand the number of tests that can be performed on the Minicare I-20 analyzer. The Minicare BNP* assay under development is aimed at the quantitative measurement of BNP in whole blood or plasma specimens to be used as an aid in the diagnosis of heart failure (HF).

Methods: Minicare BNP* is a one-step sandwich immunoassay to measure BNP in a droplet (~35 μL) of EDTA whole blood or EDTA plasma samples. An anti-BNP antibody coated onto the base cartridge captures the analyte while a second anti-BNP antibody coupled to magnetic nanoparticles recognizes complexes of capture antibody and BNP thereby allowing detection by f-TIR detection optics. The assay is standardized against the Siemens Advia Centaur BNP assay.

Results: The LoB was found at 3.3 ng/L, the LoD 5.8 ng/L and the LoQ at CV20% 8.8 ng/L. Deviation to linearity is <15% across the reportable range (10 to 5500 ng/L). Repeatability was <8% and total imprecision <10% over the range. Specifically, imprecision was 8.3% at 100 ng/L and 9.4% at 35 ng/L. Whole blood/plasma recovery is between 90-110%. Method comparison studies on plasma and whole blood showed good correlation to the core lab assay Centaur BNP from Siemens.

Conclusion: Minicare BNP* offers a broad measuring range from 10 to 5500 ng/L at a total imprecision of <10% in either whole blood or plasma while displaying good correlation to core lab BNP system. This performance and considering that the Minicare BNP* assay can deliver tests results in less than 10 minutes, may make it suitable for use in the near-patient setting right at the bedside using whole blood or plasma samples.  

 

*Minicare BNP is under development. Not available for sale.


Mario BERGER, Bekx EDWIN, Alexander VAN REENEN, Deeptha VERSTEEGE, Etienne MICHIELSEN, Emmanuel MOREAU, Roland BULLENS (Eindhoven, The Netherlands)
08:30 - 17:40 #11124 - Measurement Of Dısaster Legıslatıon Knowledge Level Of Emergency Aıd And Dısaster Management Students, Çanakkale Onsekız Mart Unıversıty.
Measurement Of Dısaster Legıslatıon Knowledge Level Of Emergency Aıd And Dısaster Management Students, Çanakkale Onsekız Mart Unıversıty.

Effective intervention in disasters and the reduction of losses are dependent on the successful implementation of Integrated Disaster Management. It was aimed to measure the knowledge level of disaster legislation in 3rd and 4th grade students of the Emergency Aid and Disaster Management Department which will take place at every stage of Integrated Disaster Management in the future.

The universe of this cross-sectional work carried out between 01.03.2016-08.04.2016 is the 3rd and 4th grade students of Çanakkale Onsekiz Mart University Emergency Aid and Disaster Management Department. An example is not selected in the study to reach the entire universe.  A total of 142 students (73%) were reached. The dependent variable of the study is the knowledge level of disaster legislation, independent variables are age, sex, class, graduated school, marital status. Fifteen information questions have been used in determining the level of disaster legislation. The data were collected through a data collection form prepared by the researchers. Descriptive findings are presented in terms of number, percent, mean, ± standard deviation.

In this study, 57 (40%) women and 85 (60%) men were interviewed with a total of 142 people.Which law is aimed at taking necessary measures to ensure that disaster and emergency situations and civil defense preparedness services are effectively implemented at the country level? 109 people answered correctly, 23 people answered wrongly. Which board is authorized to make decisions on all matters concerning emergency situations within the Disaster and Emergency Management Centers Regulation?  97 people answered correctly, 45 people answered wrongly. What are the activities named to provide services for rescue of life and property,  emergency, health, security and environmental protection, social and psychological support in the disaster and emergecy situation? 101 people answered correctly, 41 people answered wrongly. Chemical Biological Radiological Nuclear (CBRN) In the Regulation on Hazards, what is the area defined as "dangerous area that is under the wind, environment and life threatening from the threshold value at which the risk start is determined"? 120 people answered correctly, 22 people answered wrongly. Which of the following is not the Ministry of Health's duties and responsibilities under the Regulation on Chemical Biological Radiological Nuclear (CBRN) Hazards? 120 people answered correctly, 22 people answered wrongly. The average correct number of participants is 12 (80%).

Emergency  Aid and Disaster Management Department students' knowledge level of disaster legislation was determined to be high. Preparations necessary for the disaster management system to be able to reach the planned targets the continuation of the theoretical lessons on disaster legislation should be provided to the students of the emergency aid and disaster management department.


Sevda DEMİRÖZ, Gürkan ERSOY (Izmir, Turkey), Fatma AKAN
08:30 - 17:40 #11830 - Measuring the Impact of Emergency Medical Services on Patient Outcomes: A Study of Road Traffic Accident Victims in South India.
Measuring the Impact of Emergency Medical Services on Patient Outcomes: A Study of Road Traffic Accident Victims in South India.

Study/Objective:

This is an ongoing study of Emergency Medical Services (EMS) utilization for road traffic accidents (RTA) in southern India to determine 1) proportion of victims transported by ambulance, 2) crude morbidity and mortality rates in patients brought by ambulance versus other modalities.

Background:

A number of independent and hospital based organizations provide prehospital care services in India. Many have raised concerns that lack of centralization and regulation in the EMS system has caused more harm than benefit. It is not known, however, the degree to which these services are utilized nor if EMS utilization improves patient outcomes. Further investigation is warranted to identify strengths and weaknesses of prehospital care services in India.

Methods:

A retrospective chart review is being conducted at four tertiary care hospitals in South India. All patients presenting for emergent care following RTA from January 2016 to December 2016 are included. Data on 1) demographics, 2) transport, 3) injury mechanism and type, 4) hospital course, and 5) outcome, obtained from emergency department and hospital records, is being collected and managed using REDCap. Impact of EMS usage on trauma score, duration of hospital stay, ICU stay and mortality are being assessed.

Results:

Preliminary data indicate ambulances transport less than 50% of accident victims (188 of 530 road traffic accident victims). Patients utilizing ambulance services tended to have a lower revised trauma score (RTS) on arrival to the hospital (14% of ambulance transports had an RTS <6) as compared to those using other transport modalities (7% of non-ambulance transports had an RTS < 6).

Conclusion:

The study is ongoing. The current data suggest that a significant proportion of RTA victims do not arrive by ambulance and those utilizing ambulance services are more critical on arrival to the emergency department. We hope to further review the data to determine if EMS transport confers advantage to crash victims and advise changes to improve EMS-based outcomes.


Sravani ALLURI (Boston, USA), Srihari CATTAMANCHI, Amalia VOSKANYAN, Ritu SARIN, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #9902 - Mediastinal Hematoma following a 21-year-old male in traffic accident.
Mediastinal Hematoma following a 21-year-old male in traffic accident.

Mediastinal hematoma with a compressive effect on the cardiac cavities is an uncommon and serious complication of closed thoracic traumatisms.

The case of a 21 - year - old man, with no history of interest, who suffers a traffic accident by frontal collision at 50 km / h, occupies the seat of the co - driver with the seat belt in place. He went to the ER on his own terms, referring to a moderate-intensity centro-thoracic pain.

 

            At that time, the constants and physical examination were normal, with the only pain data being pressure on the lower third of the sternum. A simple radiology study was performed, with a posterior dislocation of the xiphoid process (figure 1), an electrocardiogram showing a sinus rhythm with an incomplete right bundle branch block, and an analytical one, with a normal hemogram and troponin levels High. Three hours after his arrival in the emergency room, the patient presented with progressive malaise, with pallor and hypotension. A thoracic scanner was performed with a bulky anterior mediastinal hematoma with compressive effect on right heart cavities, due to active bleeding of the left internal mammary vein (Figures 2 and 3). The patient underwent urgent videothoracoscopy with closure of the bleeding vessel and placement of pleural drainage, presenting a favorable posterior evolution.

 

Mediastinal hematomas are caused by a lesion of the mediastinal vessels, sometimes secondary to a sternal or vertebral fracture. In the most severe cases they can lead to cardiac tamponade of extrapericardic origin, a potentially fatal complication. In the first moments, the symptoms and the physical examination may not be relevant, with absence of symptoms of both acute bleeding and the classic ones of cardiac tamponade (bradycardia, jugular engorgement, paradoxical pulse).

 

The case points to the importance of maintaining a high degree of suspicion of mediastinal hematoma, despite an initial period of hemodynamic stability, in the presence of a patient with a closed thoracic trauma. In relation to our case, it is also worth remembering the relationship between the use of seat belts and sternal fractures. Early diagnosis facilitates the rapid management of this potentially serious situation.

 

 

……………………………………………………………………………….

 

 Evans PD, Mackie IG. Fracture of the body of the sternum associated with the use of static seat belts. Injury 1985;16:485-6.

 

Restifo KM, Kelen GD. Case report: Sternal fracture from a seatbelt. J Emerg Med. 1994;12:321-3.


Valentina ACOSTA RAMÓN, Maite Estibaliz LÓPEZ DE GOICOCHEA-SAIZ., Emilio PARIENTE RODRIGO, Maria Pilar CARLOS GONZALEZ (santander, Spain), Noelia SANTOS MENDEZ
08:30 - 17:40 #11117 - Medical care at home: the optimal level of care in the future for our frail elderly.
Medical care at home: the optimal level of care in the future for our frail elderly.

BACKGROUND: The elderly population in Sweden are predicted to increase the coming decades. Older adults are often high-consumers when it comes to health care and this will be a major challenge for health care, home health care and social services in the future. There are many risks associated with hospital admission for the geriatric patient; increased risk of delirium, falls, infections, bed-ulcers and thrombosis. Reducing unnecessary ED-visits, admissions to the hospital and re-admissions are of great interest to policymakers and health system in order to both decrease morbidity and mortality, and be cost-effective for the society. To be able to meet these coming challenges we need to change the location and manner by which we treat older adults. While home care is commonly attempted as a substitute for inpatient admissions, it is often poorly coordinated with patients’ medical care, sacrificing its potential effectiveness. To be able to do this we need to strengthen the collaboration between home health care, primary care and in-hospital.

AIM: Avoid unnecessary ED-visits and diminish the risk of admission to the hospital for older adults by offering physician-managed home health care and better coordination between different levels of care.

METHOD: In the municipality Halmstad, Region Halland, a new intervention project was introduced in May 2015 where nurses in home health care can consult a physician when they discover a worsening in an older patient’s condition. To avoid unnecessary visits to the ED or admission to the hospital the physician can either manage the patient remotely (through investigations, treatments, and prescriptions done by the visiting nurse) or perform a home visit the same day. When launched the intervention where running Monday-Friday between 8-16. 50 % staffed by a general physician from primary care and 50 % staffed by a physician from the hospital of Halmstad. Priority patients for this intervention are: Worsening in medical condition where a fast assessment by a physician is needed, patients at risk of admission to the hospital, patients that are at risk of re-admission to the hospital, end-of-life care decisions. This study is a descriptive study to describe the interventions made.

CONCLUSION: It is of great importance to offer high-quality and cost-effective care to older adults, a frail and growing patient group. With this new intervention it is possible to increase coordination between primary care and home health care for vulnerable patients through a dedicated care collaboration system. We expect that by offering high-quality medical treatment at home we can reduce ED-visits, admissions and re-admission to the hospital for frail older adults. We will continue to study this new intervention during 2017 and evaluate what effects it has had in the region a few years after implementation and how this strengthens the cooperation between home health care, primary care and in-hospital care. 


Karin ERWANDER, Dr Karin ERWANDER (Gothenburg, Sweden), Harveen BERQUIST, Zayed YASIN, Philip ANDERSON, Mona LANDIN-OLSSON, Kjell IVARSSON
08:30 - 17:40 #9973 - Medical Emergencies About Foreign Tourists in Japan.
Medical Emergencies About Foreign Tourists in Japan.

Background
During 2015, 19.7 million tourists visited Japan and the number of medical emergencies among them has increased over the past 10 years. This topic has not been epidemiologically investigated, and methods to support foreign patients in emergency rooms need to be determined.

Methods
This retrospective study reviewed medical records from six hospitals in Japan between January 1 - December 31, 2015 and then analyzed the nationalities, languages, chief complaints, diagnoses, and admission rates of tourists.
 
Results
Among 61 tourists who were transported to hospitals by ambulance, East Asians, South-East Asians, Europeans, and North Americans accounted for 60.7%, 17.9%, 9.8%, and 3.3%, respectively. Chinese was the most prevalent language (44.2%) and 26.2% of patients could respond in English. The most common chief complaints involved the musculoskeletal system (31.1%), followed by abdominal pain (16.4%). The most common diagnoses were limb trauma (31.1%) and ureteral stones (8.2%). Among 12 (19.7%) patients who required hospital admission, surgery was required for 4 (6.3%) with bone fractures and 3 (3.3%) with abdominal pain, and 1 (1.6%) patient with fever died of sepsis.
 
Conclusions
Many Chinese patients were delivered by ambulance to emergency rooms during 2015. Most Japanese doctors do not speak Chinese, which caused difficulties with obtaining medical histories. However, body language and medical tests helped to conclude diagnoses and determine appropriate treatment. Trauma and gastrointestinal surgeons as well as Chinese translators are needed to provide appropriate care for tourists.


Masui NOBUTAKA (Sapporo, Japan)
08:30 - 17:40 #10836 - Medullary aplasia in a 41-year-old patient who consults for asthenia in an episode of acute pharyngotonsillitis.
Medullary aplasia in a 41-year-old patient who consults for asthenia in an episode of acute pharyngotonsillitis.

NAMC. No Toxic Habits

Personal history: migraine in punctual treatment with rizatriptan

 

A 48-year-old patient presented to the emergency department for asthenia of moderate effort accompanied by palpitation in the context of pharyngotonsillitis treated with amoxicillin 500 mg every 8 hours for 4 days. It refers to the fact that dexketoprofen and hydroxyzine have been used.

 

EF: Good general condition, afebrile eupneic, mucocutaneous pallor

Cardiopulmonary auscultation: Breathless rhythm, preserved vesicular murmur.

Abdomen: soft and depressible without masses or megalias, Blumberg negative negative Murphy, negative puncture of the kidney.

Lower limbs: no signs of deep venous thrombosis, preserved pulps.

 

Supplementary tests:

 

Blood analysis: Hb 5.2 (VCM 109 HCM 37.9 CHC 34.5, leukocytes 2.6 (15% neutrophils) Platelets 4,000, reticulocytes 7, TP 83%, Glucose 141 creatinine 1.04, FG 85, Urea 4.8 Na 143 K 4.10 CL 104 Calcium 8.5, LDH 194, AST 19, ALT 18 GGT 24 FA 63, bilirubin 0.60, PCR 35.

 

Chest X-ray: Normal cardiothoracic index without costophrenic sinuses or signs of condensation.

 

EKG: Sinus rhythm at 84 bpm without alterations of repolarization.

 

Abdominal ultrasound and pelvis: No pathological findings.

 

During the stay in the emergency observation area, 3 red blood cells and a pool of platelets are transfused. It is contacted with hematology that informs peripheral blood smears and attends admission.

 

Blood smear: Red series with a macrocytic tendency of acceptable morphology with presence of isolated dacryocytes. Confounded thrombopenia. Leukopenia with severe neutropenia and presence of PMNs. Mature lymphoid population. No blasts are observed.

 

During admission,

 

Bone marrow aspirate: Extensions of medullary blood with minimal cellularity with predominance of polymorphous lymphocytes and some plasma. No megakaryocytes are observed. Increase of macrophagic cellularity with abundant detritus and osteoblasts arranged in accumulations.

 

Bone marrow biopsy: Isolated erythroid nests are observed, with very little myeloid series, with no megakaryocytes evident. Mild interstitial lymphoplasmacytic infiltrate, without aggregate formation. Presence of ferric deposits. No increase in immature precursors of CD34 + is observed. Conclusion: bone marrow biopsy compatible with spinal Aplasia.

 

Negative serology for viral PCR, Cytomegalivirus, Epstein Barr virus, Human immunodeficiency virus, Parvovirus B19, Virus hepatitis.

 

After diagnosis of medullary Aplasia, treatment with traxenamic acid, cyclosporine, folic acid, prednisone, magnesium and voriconazole is initiated.

 

CONCLUSION: In many cases hematological diseases are manifested in the emergency department in the context of catarrhal pictures without improvement accompanied by asthenia.

In patients who report asthenia associated with clinical data that inform us of possible anemia, we must perform a blood test to confirm these alterations.


Rafael INFANTES RAMOS (Málaga, Spain), Cristina FERNANDEZ- FIGARES MONTES, Maria Eugenia REYES GARCIA, Manuel AGUILAR CASAS, David NUÑEZ CASTILLO, Ivan VILLAR MENA
08:30 - 17:40 #11378 - Mesenteric panniculitis. Acute abdominal pain.
Mesenteric panniculitis. Acute abdominal pain.

Mesenteric panniculitis is an inflammatory disorder involving the adipose tissue of the mesentery. In most cases it´is asymptomatic although the patients may present with abdominal pain, diarrhea, weight loss or abdominal mass, and only rarely with symptoms of acute abdominal pain. The etiology of mesenteric panniculitis is unknown, ischemia, infection, abdominal trauma, previous abdominal surgery, and autoimmune disorders have been reported as possible causative agents. It has also been suggested its association with drugs, malignancy, and inflammatory processes. Epidemiologically it predominates in the masculine sex 2-3:1, being more frequent between 50-70 years.Computed tomography (CT) is the gold standar imaging technique for its diagnosis. Different drugs have been used for its treatment: corticoids, colchicine, dapsone, tamoxifen, immunosuppressants, although cases of spontaneous remision have been described.

We report 2 cases of patients who presented at the Emergency Department with acute abdominal pain and were diagnosed with mesenteric panniculitis.


Maria De La Peña LOPEZ-GALINDO (ZARAGOZA, Spain), Beatriz SIERRA, Maria Jose GIMENO, Blanca MARADIAGA, Alba HERNANDEZ
08:30 - 17:40 #10997 - mesentric panniculitis case report and literature review.
mesentric panniculitis case report and literature review.

Mesenteric panniculitis : a case report and literature review


Mona ELGHARBAWY (doha, Qatar), Ahmed ABOUELLIF
08:30 - 17:40 #11546 - Metaldehyde poisoning, something unusual.
Metaldehyde poisoning, something unusual.

Poisonings can become real life-threatening emergencies, despite all the knowledge about toxicology, sometimes we face with substances that are not well known because of their lack of frequency. This is the case of metaldehyde.

We present the case of a 66 year old woman, widow for 10 years, who lived alone and who had been depressed over the last three months. She had no treatment for depression. On her medical record she had a suicide attempt with rat poison eight years ago. She was found unconscious, unresponsive to stimuli and with sialorrhea by her daughter on her house, next to her were remains of slug killer with a concentration of 5% metaldehyde. When the ambulance arrived she had a blood pressure of 150/90 mmHg, cardiac frequency of 75 bpm, respiratory frequency of 16, oxygen saturation of 97%, temperature of 34,2ºC and a GCS of 9, a high flow oxygen was placed and as well as an intravenous route; upon her arrival to the emergency room her GCS lowered to 3, so she was intubated and a nasograstric tube was placed. Blood tests were performed and were normal, arterial blood gas analysis revealed a respiratory acidosis with pH 7,27. Partial pressure oxygen 78,8. Partial pressure carbon dioxide 56,5. Standard bicarbonate of 25 mmol/l. Toxicology exams came back positive for benzodiacepines. A CT Scan was performed and it was normal. She was admitted to the intensive care unit. On the suspicion of poisoning, flumazenil was administrated; after it was administrated the patient presented a seizure which was treated with midazolam. Treatment with levetiracetam was started and an electroencephalogram was performed and as she remained on status epilepticus, phenytoin was added and the levetiracetam dose increased. Over the next days she presented clinical improvement so she was extubated on the seventh day. Another electroencephalogram was made and it came back normal. She was discharged from the ICU and admitted to the intermediate care unit were she was treated by the psychiatry and the internal medicine team. The psychiatrists started treatment with escitalopram 5 mg bid, while the internal medicine team began to lower the dose of phenytoin and levetiracetam. The patient could never calculate the dose of metahldehyde that she had ingested. 

Metaldehyde (C8H16O4) is a cyclic tetramer of acetaldehyde used as molluscicide againts slugs and snails. It can be absorbed by the gastric system into the bloodstream or through contact with skin and lungs. Upon entering the body, it decomposes into acetaldehyde, which can cross the blood-brain barrier altering the level of consciousness. Salivation, facial flushing, fever, abdominal pain, nausea and vomiting are present even after the ingestion of trace amounts; drowsiness, tachycardia, spasms and irritability with up to 50 mg/kg; ataxia and increased muscle tone at 50-100 mg/kg; convulsions, tremor and hyperreflexia at a100-200 mg/kg and coma or death after doses of approximately 400 mg/kg.


María Del Pilar CARLOS GONZÁLEZ (santander, Spain), Noelia SANTOS MÉNDEZ, Valentina ACOSTA RAMÓN, Marta BÁSCONES GARCÍA, Magdalena FERNÁNDEZ GARCÍA, Ascensión JORRÍN MORENO, Marta PASTRANA FRANCO
08:30 - 17:40 #11762 - Methotrexate therapeutic error in non-oncology setting.
Methotrexate therapeutic error in non-oncology setting.

Methotrexate (MTX) originate as antineoplastic drug, but, from several years, it is largely used also in autoimmune/rheumatic diseases for its antiphlogistic properties. Adverse reactions are described after therapeutic dose, especially in patients with risk factors (e.g. renal impairment, drug-drug interactions, predisposing genetic polymorphisms). Moreover, MTX spread in outpatients may increase also the possibility of therapeutic error. High risk of toxicity is related to overdose. Objective: To evaluate the characteristics of the cases of MTX overdose due to therapeutic error in non-oncology patients. Methods: All cases of MTX overdose due to therapeutic error in non-oncology patients referred to our Poison Control Centre were retrospectively evaluated in a 8-year (06/2007-06/2016) retrospective study. Data about patients, intoxication circumstances and clinical manifestations were analysed. Results: 35 cases were included (50% male), aged between 17 and 86 years. In 5 cases patients were nursing mothers (not in treatment) to which MTX was wrongly sold by pharmacist instead of methylergometrine. In the remaining 30 cases, it came to patients who assumed prescribed MTX for the first time in their life for an autoimmune/rheumatic disease. In 27 cases wrongly assumption of prescribed dose occurred, in 2 patients MTX was administrated by incorrect way, and in 1 case was administrated despite presence of severe renal failure. In all the 28 patients that underwent an assumption error, the weekly prescribed dose (range: 2.5–12.5 mg/week) was daily assumed (=17.5-87.5 mg/week); this mistake was recognized after a period ranging from 2 to 21 days. Clinical manifestations were characterized by mucositis (14/35), myelosuppression (12/35), asthenia (6/35), acute renal failure (5/35), diarrhea (4/35), vomiting (4/35), headache (2/35), hepatitis (2/35). All patients were treated with calcium levofolinate and forced alkaline diuresis. N-acetylcisteine was administered in 2 patients with hepatitis, and growth-factors in one. MTX plasma levels were available for 6 patients, resulting within recommended therapeutic range. No lethal cases were registered. In the 5 nursing mothers breastfeeding was stopped for 4 days. Conclusions. Medication errors is a cause of MTX toxicity. Most assumption errors are due to misunderstanding of medical prescriptions. Clear indications, possibly with electronic systems and explication to the patients are necessary in order to avoid these errors and the consequent toxicity. MTX serum quantitative determination is useful during therapy and to administer the correct dose of antidote in acute overdoses, but is not a good predictor of outcome in chronic overdose, due to the pharmacokinetic characteristics of the drug.


Azzurra SCHICCHI, Valeria Margherita PETROLINI, Francesca CHIARA, Sara DI GIULIO, Giulia SCARAVAGGI, Sarah VECCHIO, Carlo Alessandro LOCATELLI, Davide LONATI (PAVIA, Italy)
08:30 - 17:40 #11437 - Metilfenidat overdoses : in a PED.
Metilfenidat overdoses : in a PED.

Aim: Metilfenidat  (MFT)  are being widely used in the treatment of Attention  Deficit Hyperactivity Disorder  (ADHD). As an outcome of this, it’s increasingly reported MFT poisonings.  In this report, we analysed children that poisoned with MFT as a single agent.

 Material -Method: During 1st Jan 2013 -31st  Dec 2015 , in a pediatric emergency department (ED) of a university hospital, 32  patients poisoned with Metilfenidat as  a single agent were evaluated retrospectively. Age, sex, mental status at arrival to ED Glasgow Coma Scale (GCS), , comlete blood count (CBC), arterial blood gas analyses, ECG, symptoms on follow-up and time interval from arrival to discharge.

Results: Patients’ mean  age was  +10.96 (1.5-17),  10  of  patients were intentionally poisoned (with the aim of suicide) and  6 of these patients were female and older than ten years old. 22  patients (sixteen  patients were male) were unintentionally poisoned patients and younger than ten years old.  Thirty patients were treated MFT related with  ADHD. Time interval between ingestion of  MFT and arrival to the ED 2.5  hours. Sypmtoms were altered mental status (18  patients), vomiting (21 patients), seizure (8 patients). GCS score was lower than 15 in 18  cases. CBC, electrolytes, renal and liver function tests were normal in all patients. All patients were applied gastric lavage, charcoal . 12 patients had a distonic reaction and threated with biperiden hydrochloride .  Eighteeen  of  them  stayed in critical care unit for 6-72 hours and mean time for hospital stay was  52 hours.All patients were re-examined at 2 weeks from discharging and there were no pathological signs and symptoms.

 Conclusion: A physician must be alert for MFT intoxication in conditions that altered mental status, low GCS score,seizure and  Distonic Reactionand histort ADHD . Early diagnosis, monitorisation and symptomatic treatment were needed.

 

 

Aim: Metilfenidat  (MFT)  are being widely used in the treatment of Attention  Deficit Hyperactivity Disorder  (ADHD). As an outcome of this, it’s increasingly reported MFT poisonings.  In this report, we analysed children that poisoned with MFT as a single agent.

 Material -Method: During 1st Jan 2013 -31st  Dec 2015 , in a pediatric emergency department (ED) of a university hospital, 32  patients poisoned with Metilfenidat as  a single agent were evaluated retrospectively. Age, sex, mental status at arrival to ED Glasgow Coma Scale (GCS), , comlete blood count (CBC), arterial blood gas analyses, ECG, symptoms on follow-up and time interval from arrival to discharge.

Results: Patients’ mean  age was  +10.96 (1.5-17),  10  of  patients were intentionally poisoned (with the aim of suicide) and  6 of these patients were female and older than ten years old. 22  patients (sixteen  patients were male) were unintentionally poisoned patients and younger than ten years old.  Thirty patients were treated MFT related with  ADHD. Time interval between ingestion of  MFT and arrival to the ED 2.5  hours. Sypmtoms were altered mental status (18  patients), vomiting (21 patients), seizure (8 patients). GCS score was lower than 15 in 18  cases. CBC, electrolytes, renal and liver function tests were normal in all patients. All patients were applied gastric lavage, charcoal . 12 patients had a distonic reaction and threated with biperiden hydrochloride .  Eighteeen  of  them  stayed in critical care unit for 6-72 hours and mean time for hospital stay was  52 hours.All patients were re-examined at 2 weeks from discharging and there were no pathological signs and symptoms.

 Conclusion: A physician must be alert for MFT intoxication in conditions that altered mental status, low GCS score,seizure and  Distonic Reactionand histort ADHD . Early diagnosis, monitorisation and symptomatic treatment were needed.

 

 

 

Aim: Metilfenidat  (MFT)  are being widely used in the treatment of Attention  Deficit Hyperactivity Disorder  (ADHD). As an outcome of this, it’s increasingly reported MFT poisonings.  In this report, we analysed children that poisoned with MFT as a single agent.

 Material -Method: During 1st Jan 2013 -31st  Dec 2015 , in a pediatric emergency department (ED) of a university hospital, 32  patients poisoned with Metilfenidat as  a single agent were evaluated retrospectively. Age, sex, mental status at arrival to ED Glasgow Coma Scale (GCS), , comlete blood count (CBC), arterial blood gas analyses, ECG, symptoms on follow-up and time interval from arrival to discharge.

Results: Patients’ mean  age was  +10.96 (1.5-17),  10  of  patients were intentionally poisoned (with the aim of suicide) and  6 of these patients were female and older than ten years old. 22  patients (sixteen  patients were male) were unintentionally poisoned patients and younger than ten years old.  Thirty patients were treated MFT related with  ADHD. Time interval between ingestion of  MFT and arrival to the ED 2.5  hours. Sypmtoms were altered mental status (18  patients), vomiting (21 patients), seizure (8 patients). GCS score was lower than 15 in 18  cases. CBC, electrolytes, renal and liver function tests were normal in all patients. All patients were applied gastric lavage, charcoal . 12 patients had a distonic reaction and threated with biperiden hydrochloride .  Eighteeen  of  them  stayed in critical care unit for 6-72 hours and mean time for hospital stay was  52 hours.All patients were re-examined at 2 weeks from discharging and there were no pathological signs and symptoms.

 Conclusion: A physician must be alert for MFT intoxication in conditions that altered mental status, low GCS score,seizure and  Distonic Reactionand histort ADHD . Early diagnosis, monitorisation and symptomatic treatment were needed.

 

 

 

Aim: Metilfenidat  (MFT)  are being widely used in the treatment of Attention  Deficit Hyperactivity Disorder  (ADHD). As an outcome of this, it’s increasingly reported MFT poisonings.  In this report, we analysed children that poisoned with MFT as a single agent.

 Material -Method: During 1st Jan 2013 -31st  Dec 2015 , in a pediatric emergency department (ED) of a university hospital, 32  patients poisoned with Metilfenidat as  a single agent were evaluated retrospectively. Age, sex, mental status at arrival to ED Glasgow Coma Scale (GCS), , comlete blood count (CBC), arterial blood gas analyses, ECG, symptoms on follow-up and time interval from arrival to discharge.

Results: Patients’ mean  age was  +10.96 (1.5-17),  10  of  patients were intentionally poisoned (with the aim of suicide) and  6 of these patients were female and older than ten years old. 22  patients (sixteen  patients were male) were unintentionally poisoned patients and younger than ten years old.  Thirty patients were treated MFT related with  ADHD. Time interval between ingestion of  MFT and arrival to the ED 2.5  hours. Sypmtoms were altered mental status (18  patients), vomiting (21 patients), seizure (8 patients). GCS score was lower than 15 in 18  cases. CBC, electrolytes, renal and liver function tests were normal in all patients. All patients were applied gastric lavage, charcoal . 12 patients had a distonic reaction and threated with biperiden hydrochloride .  Eighteeen  of  them  stayed in critical care unit for 6-72 hours and mean time for hospital stay was  52 hours.All patients were re-examined at 2 weeks from discharging and there were no pathological signs and symptoms.

 Conclusion: A physician must be alert for MFT intoxication in conditions that altered mental status, low GCS score,seizure and  Distonic Reactionand histort ADHD . Early diagnosis, monitorisation and symptomatic treatment were needed.

 

 

 

 


Sabiha SAHIN, Sabiha SAHIN (Eskisehir, Turkey)
08:30 - 17:40 #10851 - Migration-specific issues of patients of an university Emergency Department.
Migration-specific issues of patients of an university Emergency Department.

Migration-specific issues of patients of an university Emergency Department

Background: An increase in the utilization of Emergency Departments (ED) of hospitals can be observed in whole Europe and in most of the industrialized countries. Due to the current wave of refugees, this topic is becoming more important, especially for the European region. In major cities a relevant part of the patients in the EDs are already immigrants, so far they have not been adequately represented in health care research.

Methods: This retrospective study investigates the utilization of a big university ED by immigrants, regarding the number of patients categorized by socio demographic issues, age, gender, weekday of consultation and the type of referral over a period of ten years.

Results: 264727 patients were included in the data analyses; 201260 were Suisse citizens, 27290 immigrants of other European countries and 35722 came from other continents. There was a general increase of 48% in the number of total admitted patients; with that annually increasing number of treatments, there is a disproportionately high increase of foreign patients. In 3% of the cases patients were immigrants from other European countries over the period of ten years, whereas the number of patients of non-European countries raised from 4,5% to 6,5% significantly.  60% of patients of other continents were male and younger with an age between 20 to 29 years. Most of the immigrants admit the ED on weekends especially on Saturday, opposite to most of the European patients who admit the ED at the beginning of the week. 67% of the self-referrals patients come from a non-European country, compared to only 7% referrals of these patients by family practitioners probably due to lower knowledge and integration into the local health system with e.g. the community supply of general practitioners.

Conclusions: There was a general increase of 48% in the number of total admitted patients in the Emergency Department similar to the increase of the utilization of Emergency Departments in most of the industrialized countries. The number of younger patients from non-European countries treated in the Emergency Department increased during the study period of ten years significantly. 67% of the self-referrals patients come from a non-European country, compared to only 7% referrals of these patients by family practitioners probably due to lower knowledge and integration into the local health system. This trend will further continue and the sociodemographic structures should be taken into account regarding the emergency care reserve capacity.


Christian BRAUN (Bern, Switzerland), Cornelia GNÄGI, Meret RICKLIN, Aristomenis EXADAKTYLOS
08:30 - 17:40 #11693 - Mitofusin 2 promotes the apoptosis of CD4+ T cells via inhibiting autophagy in sepsis.
Mitofusin 2 promotes the apoptosis of CD4+ T cells via inhibiting autophagy in sepsis.

Apoptosis of CD4+ T cells is a primary pathophysiology mechanism of immune dysfunction in the pathogenesis of sepsis. Mitofusin 2 (Mfn2), an integral mitochondrial outer-membrane protein, has been proved to be associated with cellular metabolism, proliferation, and apoptosis. The function of Mfn2 on CD4+ T-cell apoptosis in sepsis is poorly understood. Here we discovered in vivo increased Mfn2 expression, deficient autophagy and elevated cell apoptosis in murine splenic CD4+ T cells after cecal ligation and puncture (CLP). On the other hand, we observed almost identical result in splenic CD4+ T cells upon lipopolysaccharide (LPS) stimulation in vitro. Furthermore, overexpression of Mfn2 resulted in impaired autophagy and increased apoptosis in Jurkat cells. Pharmacological inhibition of autophagy with 3-methyladenine enhanced Mfn2 overexpression-induced cell apoptosis. In addition, overexpression of Mfn2 down-regulated PMA/ionomycin-, rapamycin- and starvation-induced autophagy in Jurkat T cells. Taken together, these data indicate a critical role of Mfn2 in apoptosis of CD4+ T cells in sepsis and the underlying mechanism of autophagy deficiency.


Ying LAN, Lu ZHONG-QIU (Wenzhou, China)
08:30 - 17:40 #11495 - Modification of Glasgow Blatchford Scoring with lactate in predicting the mortality of patients with upper gastrointestinal bleeding in emergency deparment.
Modification of Glasgow Blatchford Scoring with lactate in predicting the mortality of patients with upper gastrointestinal bleeding in emergency deparment.

Aim: The purpose of this study is; to investigate the efficacy of “Glasgow Blatchford Scale (GBS) + Lactate levels” to predict the mortality of gastrointestinal bleeding patients detected in the emergency department.

 Methods: A total of 107 patients with preliminary diagnosis of upper GI bleeding that were included in the study after approval of the ethics committee were prospectively evaluated. GB scores were calculated and venous blood lactate level was assessed. Need of blood transfusion in follow up, amount of transfusion and mortality in next 6 months were evaluated.

 Results: A statistically significant difference was found between mortality rates according to lactate and GBS cohort in our study (p = 0.001; p <0.01). The mortality rate was significantly higher in the lactate(+) GBS(+) cases compared to the lactate(-) GBS(+), lactate(+) GBS(-) and lactate(-) GBS(-) cases compared to the bilateral comparisons (p=0.004; p=0.001; p=0.001; p<0.01, respectively). There was a statistically significant relationship between the rate of ES replacement in the cases according to GBS levels (p = 0.001; p <0.01). The incidence of ES replacement was 7.393 times greater in patients with GBS 12 and above.

 Conclusion: GBS is high sensitive to determine the mortality risk and the need of blood transfusion in upper GIB. GBS with lactate evaluation is more sensitive and more significant than GBS alone. This significance provides us to establish “modified GBS”. In the future, studies which will use GBS supported by lactate could be increased and results should be supported more. 


Zeynep KONYAR (Istanbul, Turkey), Fatma Sari DOGAN, Eren GOKDAG, Ozlem GUNEYSEL
08:30 - 17:40 #11574 - Morbidity and mortality predicted by early vital parameter deterioration and national early warning score.
Morbidity and mortality predicted by early vital parameter deterioration and national early warning score.

Track and trigger systems based on vital parameters, such as the National Early Warning Score (NEWS), aim to detect and react to patients at risk of clinical deterioration. It has not been studied how change in NEWS over time predicts adverse outcomes. Aims: To determine whether early deterioration in NEWS predicts morbidity and mortality among hospital admitted patients. Material and Methods: Retrospectively, data on 19,837 patients over 17 years old admitted to Karolinska University Hospital from the emergency department was collected. Exclusion criterion was inadequate NEWS measurements. The first two NEWS measurements from hospital admittance were used. Comparison groups were stable versus increasing NEWS risk category and stable versus increasing NEWS points. The primary outcome was a combination of 7-day mortality and/or 5-day escalation of care. Relative risks were calculated. Results: A positive relationship between NEWS and the primary outcome was observed. However, no significant difference in relative risk was observed between those with increasing NEWS compared to those with stable elevated NEWS. Stratification on patients with medium NEWS risk category at the second measurement resulted in relative risk of 0.536 (CI 95% 0.366 – 0.785) for the patients with increasing NEWS risk category versus the patients with stable NEWS risk category. The general trend was towards lower relative risk for patients increasing in NEWS. Conclusions: The morbidity and mortality was similar for those with deteriorating NEWS compared to those with stable elevated NEWS. However, differences in subgroups were observed and more research is needed to determine if there is a difference in certain patient groups. The results support the consensus that increasing NEWS correlates to increasing adverse outcomes and validates NEWS for a Swedish setting.


Jonas NILSSON (Stockholm, Sweden), Therese DJÄRV, Per SVENSSON, Umut HEILBORN
08:30 - 17:40 #10974 - More than anxiety.
More than anxiety.

Clinic history:

•Personal history:

HTA, anxious-depressive syndrome. Smoking 15 cigarettes / day. Usual treatment: amlodipine 5mg / 24 hours, fluoxetine 20mg / 24 hours, alprazolam 1mg / 24 hours.

•Anamnesis:

Refers to oppressive thoracic pain irradiated to both upper limbs, two hours in duration that begins at rest along with nausea. The patient at home takes alprazolam with which she shows slight improvement. That same night in her building the patient has witnessed a fire in a house near her own which caused her nervousness. Multiple attendances in emergency service due to anxiety crisis. 

•Exploration:

TA: 145/90, HR: 85 bpm, Oxygen saturation: 98% basal, resting euphonic. Cyc: picnr, no lymphadenopathy, no jugular engorgement, palpable and symmetrical carotid pulses. Ac: rhythmic without blows. Ap: mvc without pathological noises. MMII: no edemas, no signs of tvp, present pulses.

• Supplementary tests:

  - Blood analysis: hemogram and hemostasis without alterations, biochemistry: CK-MB 63.1, troponin I 8.78, Second determination: CK-MB 87.9, troponin 12.4. Third determination CK-MB 71.3

  - ECG: sinus rhythm, 65 bpm, normal axis, pr <0.20, qrs <0.12, q from V1 to V3, flattened V1-V6, isoelectric.

  - Chest x-ray: normal ict, no condensation image, no sinus clamping.

  - Catheterization: angiographically normal coronary arteries. Antero-inferior-apical hypokinesia. FE 45%.

  - Echocardiogram: mitral and aortic valve with normal opening, right-sized normal cavities, non-dilated left ventricle, or hypertrophic, with septal hypokinesia and normal global contractility. No pericardial effusion. Preserved systolic function. 

Evolution:

She entered coronary ICUs, catheterization was performed on a scheduled basis, during his stay in uci and plant without incidents 

Conclusions:

Tako-Tsubo sindrome it is a type of non-ischemic cardiomyopathy in which there is a sudden temporary weakening of the myocardium, which can be triggered by emotional stress.


María Del Carmen FAZ GARCÍA, David NUÑEZ CASTILLO (SPAIN, Spain), Rafael INFANTES RAMOS
08:30 - 17:40 #11609 - Morphine in the pre-hospital treatment of cardiogenic pulmonary edema.
Morphine in the pre-hospital treatment of cardiogenic pulmonary edema.

Background: Morphine is considered a traditional medication to relieve dyspnea in the setting of cardiogenic pulmonary edema (CPE). However, there have been published in-hospital clinical studies bringing in controversies this indication regarding increased risk of intubation and mortality. Therefore, we realized retrospective clinical study to analyze whether morphine administration within the initial pre-hospital treatment of CPE is associated with increased risk of further pre-hospital mechanical ventilation and out-of-hospital cardiac arrest (OHCA) developing during pre-hospital management.

Methods: Emergency medical service (EMS) of the Central Bohemian Region is the exclusive provider of primary prehospital emergency care in the Central Bohemian Region, Czech Republic (1315299 inhabitants on a total area of 11015 km2). A computer search of patients with CPE between 1.1.2013 and 31.1.2014 was conducted. Thereafter, a statistical analysis including multivariate logistic regression to evaluate predetermined goals of the study was performed.

Results: For the selected period a total of 901 CPE patients was treated by EMS in selected region. Morphine was administered as a part of initial management in 14,9%. Its use in the pre-hospital therapy of CPE was an independent predictor of increased risk of the need for mechanical ventilation (OR 3.59; 95% CI 1.60-8.07; p=0.002). On the contrary, we did not identify any association with the risk of further OHCA (OR 1.21; 95% CI 0.21-5.26; p=0.807). Other independent predictors of the increased risk of mechanical ventilation in the field were age less than 80 years (OR 2.47; 95% CI 1.10-6.07; p=0.036), acute coronary syndrome as a cause of CPE (OR 6.56; 95% CI 1.93-20.14; p=0.001), hypotension (OR 8.22; 95% CI 2.95-22.72; p<0.001) and hypoxia (OR 4.23; 95% CI 1.64-13.17; p=0.006) in the first measurement and administration of corticosteroids in initial treatment (OR 4.87; 95% CI 1.17-17.80; p=0.021). Medical history of permanent cardiac pacing (OR 16.8; 95% CI 2.19-126.29; p=0.005) and stroke (OR 10.95; 95% CI 2.72-45.72; p<0.001), initial hypotension (OR 35.96; 95% CI 7.72-205.49; p<0.001) and administration of corticosteroids (OR 18.70; 95% CI 2.24-149.37; p=0.005) independently predicted higher risk of OHCA during pre-hospital management.

Discussion: In our study, morphine administration in the initial pre-hospital therapy of CPE was independently associated with increased risk of further pre-hospital mechanical ventilation. We did not identified any association with the risk of OHCA. Although there is no reliable evidence either supporting or rejecting the use of morphine in CPE, these results support the approach that morphine should not be used in this indication routinely, but after careful individual consideration only. Surprising finding is that initial corticosteroid treatment was associated with negative early outcome in CPE patients. This will be the subject of further research.


Callerova JITKA (Kladno, Czech Republic), Skulec ROMAN, Knor JIRI, Merhaut PATRIK, Cerny VLADIMIR
08:30 - 17:40 #11700 - Most Neonates Use The Emergency Department For Primary Care ; Preliminary Report Within Six Months.
Most Neonates Use The Emergency Department For Primary Care ; Preliminary Report Within Six Months.

Background

Although the most neonatal emergencies are fairly benign, this trend may be changing. Since earlier newborn discharges from hospitals and the lack of prenatal care in our country, emergency departments (EDs) are seeing an increase in newborn visits.

Objectives

  1. To analyze the factors affecting neonatal admissions to a pediatric emergency department,
  2. To evaluate  their  progress and outcomes following discharge or hospitalization

Material and Methods:

We organized a prospective cohort study for one year period. All neonates aged 28 days or less admitted to the pediatric ED started to enroll by September 2016. This is only a preliminary report of our study. The data collected for neonates were age, sex, delivery method, premature or term birth, feeding mode, time of admission, re-admission rate, the length of stay, and progression. Presenting complaints, frequent diagnoses and rate of hospitalization also were recorded.

Results:

A total of 976 (2.4%) neonates were enrolled among 39.918 children admitted to the ED in the first 6 months of our study period. 53.2% were males. Mean age was 7.5 days the male: for female ratio was 1.21. More than half of newborns (55.3%) visited the ED at out of hours.  Ambulance utilization rate was only 1.1%. We identified exclusive breastfeeding rate as 79,3%. The most common presenting complaint was jaundice (72,1%). The major diagnoses were ‘normal neonate’ (71.8%) and hyperbilirubinemia (9,8%). In 14.1%, hospital admission was necessary and the most common causes of hospitalization were indirect hyperbilirubinemia (61.3%), severe sepsis (16.1%), acute life-threatening event (6.5%), respectively. Only 174 newborns (17.8%) presented with serious events (sepsis, required phototherapy, pneumoniae, ALTE etc.) and sudden infant death syndrome occurred only one patient. Newborns with referral (by physician) and those with less than 37 weeks of gestation were more likely to be admitted. Re-admission rate was higher in early neonate (≤ 7 days) and older maternal age. 

Conclusions:

Most visits in our ED occured because of nonserious diseases, mainly because of insufficient caretaker knowledge and information. It is important that physicians are aware of the main illnesses in the neonatal period and know how to identify and manage the conditions associated to serious pathology


Caner TURAN, Gulsum KESKIN (Izmir, Turkey), Ali YURTSEVEN, Eylem Ulas SAZ
08:30 - 17:40 #10870 - Mucormycosis rhinocerebral in male of 46 years with diabetic ketoácidosis.
Mucormycosis rhinocerebral in male of 46 years with diabetic ketoácidosis.

Personal history

No allergy to medications. No Toxic Habits
Non-insulin dependent diabetes mellitus on treatment with vidagliptin 50mg / metformin 850mg every 24 hours and glycation 60mg / 12 hours

Current illness

A 46-year-old female patient who came to the emergency room by ambulance from the hospital for hyperglycemia with 525 mg / dL, tachycardia, dry mucous and general malaise. The patient entered the observation area for monitoring, beginning of treatment with insulin and complementary tests.
During admission, the patient refers to left hemicranial headache with intense pain and loss of vision in the left eye.

Physical examination

Regular general condition, cutaneous pallor, tachypnea of 35 breaths per minute with use of acceosoria musculature. Tachycardia at 125 beats / minute. Feverish

Head and neck: no oropharyngeal anomalies, no adenopathies, preserved carotid pulses. Left periorbital cellulitis with palpebral ptosis.

Cardiopulmonary auscultation;: rhythmic without blows, preserved vesicular murmur.

Abdomen: soft and depressible without masses or megalias, Blumberg negative, Murphy negative.

Lower limbs: no edema, no signs of deep venous thrombosis.

Neurology: reactive midriatic left pupil with palpebral ptosis. Paralysis of external ocular motor.

Ophthalmology: left eye fundus with edematous papilla, macular edema with punctate hemorrhages. Recommending the realization of MRI to rule out cavernous sinus thrombosis.

Supplementary tests

Blood analysis: HB 12.8 mg / dL, Platelets 438,000, Leukocytes 20,500 (88% neutrophils) glucose 475 mg / dL Creatinine 0.93 mg / dL (FG> 90) sodium 141 mEq / L Potassium 4.70 mEq / L Chlorine 100 mEq /.Normal liver enzymes,C-reactive protein 283 mg / L. Venous gasometry.PH 6.99 PCO 2 14,Bicarbonate 6.1

Chest X-ray: No pathology

EKG:Sinus rhythm at 120 bpm without alterations of repolarization.

After hemodynamic stabilization of the patient by treatment with insulin therapy, fluid therapy and bicarbonate repositioning, a skull CT was chosen.
CT skull: occupation of frontal, maxillary, ethmoidal and left sphenoid sinuses. Contiguity solution in 1 cm orbital medial wall. Integrity of both eyeballs.

During admission to the internal medicine plant,  cranial MRI is performed which reports findings suggestive of rhinosinusitis with foci of bilateral frontal encephalitis and left cavernous sinus thrombosis.

The patient is operated by otorhinolaryngology for nasosinusal endoscopic surgery in two surgical times with the objective of a necrotic plaque in the middle turbinate and mass that affects ethmoids with destruction of lamina papiracea. Fungal lesion necrotic content in hard palate. Subsequently, he underwent neurosurgery, performing bilateral fontobasal and ethmoidal craniotomy with frontal abscesses
In the pathological anatomy of different samples, micotic hyphae compatible with mucor were objectified.

One month later, the patient died from complications of nosocomial pneumonia in an intensive care unit


Alberto NUÑEZ CHÍA, Ana PÉREZ TORNERO, Rafael INFANTES RAMOS (Málaga, Spain)
08:30 - 17:40 #10966 - Multidisciplinary team perceptions about terminal extubation in a teaching hospital in Brazil.
Multidisciplinary team perceptions about terminal extubation in a teaching hospital in Brazil.

Background: Palliative extubation is performed in patients with terminal ilnesses in which mechanical ventilatian might prolong suffering. Even though the procedure involves nurses, respiratory therapists and doctors, not all of these professionals feel confortable performing a palliative extubation. Especially in low income countries, where there is usually less education on palliative care, the concept of withdrawing life support can be easily confounded with euthanasia, generating moral distress among the team.

Methods: A questionary containing 6 open ended questions concerning a hypotetical case of a catastrophic intracerebral hemorrhage and prolonged coma,  with a potential indication for palliative extubation was applied to 10 members of an emergency department intensive care unit staff (1 senior doctor, 3 first year residents, 3 nurses, 3 respiratory therapists (RT). The answers were analyzed.

Results: Half of the professionals had never participated in a palliative extubation. Four professionals (2 RTs, one doctor and a nurse) believed palliative extubation is equal to euthanasia. When asked about their own preferences in such a situation, only one respiratory therapist would like to be tracheostomized, while all other professionals would prefer palliative extubation. Tha main reason for this preference was the belief that tracheostomy and prolonged mechanical ventilation would lead to additional suffering without any improve in quality of life.

Conclusion: Palliative extubation is not commonly performed in Brazil or other low-income countries and more education about his procedure is necessary to avoid misunderstandings and reduce moral distress in the interdisciplinary team


Sabrina Correa Da Costa RIBEIRO (São Paulo, Brazil), Yasmine FILIPPO, Patricia SCHAFFER, Lucas MARINO, Lucas TAVARES
08:30 - 17:40 #11874 - Multiple ischemic strokes following percutaneous coronary angioplasty.
Multiple ischemic strokes following percutaneous coronary angioplasty.

Introduction :

Stroke after percutaneous coronary intervention is a rare complication; with an incidence ranging from 22% to 38%. This situation was correlated with high morbidity and mortality rate among litterature. We here by describe the case of a patient who developed multiple ischemic strokes after undergoing a percutaneous coronary intervention for acute coronary syndrome.

Case report:

A 68 year-old man was admitted in the emergency department with complaint of acute dyspnea. Physical examination revealed: A conscious patient without neurologic failure, excessive sweating, acute respiratory distress with a respiratory rate at 30 inspirations /min associated to struggle signs, and oximetry pulse on air of 75%. Crackles were found on on auscultation killip3, tachycardia at 145 beats/min, high blood pressure: 200/100 mmHg. The gazometry revealed severe metabolic acidosis at 7.07 with hyperlactatemia at 8.5 and severe hypoxemia. The initial electrocardiogram objectified a left branch bundle bloc.  Immediate oxygenotherapy by continuous positive air pressure (CPAP) was initiated but failed. Patient was intubated. An angioplasty was effectuated after 2 hours showing a tritoncular stenosis with stenting in the proximal interventricular artery. The evolution was marked by a wake-up delay. In this context, a cerebral computerized tomography revealed a multiple ischemic cerebrovascular accident: total sylvian and right posterior cerebral, left posterior cerebral, of the two cerebellar hemispheres ,and the brainstem. Evolution was fatal after 5 days of hospitalization.

Conclusion :

Stroke remains a rare but devastating complication of percutaneous coronary angioplasty, which is difficult to prevent even in the knowledge of predictive factors. 


Alaa ZAMMITI (Tunis, Tunisia), Hamed RYM, Sarra JOUINI, Badra BAHRI, Maroua MABROUK, Abir WAHABI, Yasmine WALHA, Chokri HAMOUDA
08:30 - 17:40 #11084 - My pupils are different…after gardening?
My pupils are different…after gardening?

Spontaneous unilateral mydriasis is an uncommon entity observed in emergency rooms (ER). The Gardener's Anisocoria occurs by contact of toxins contained in some flowers and start after rubbing the eyes during the gardening tasks. This key should be to be asked in all anamnesis of mydriasis in ER. Two cases of spontaneous unilateral mydriasis are described by contact with the genus Brugmansia, colloquially known as Floripondio or Trumpet of the angel or of the judgment.

A 19-year-old male and 32-year-old female, who underwent left unilateral mydriasis of 4 and 6 hours, respectively, without visual deficit or headache or other symptoms. Neurological examination was normal, except for a left hyporeactive mydriasis that did not respond to 2% Pilocarpine eye drops. Basic study was done with hemogram, coagulation, biochemistry, chest X-ray, electrocardiogram and Brain CT scan were normal. Patients reported having been gardening at home several hours before the onset of symptoms, both reported having rubbed her eyes prior to symptoms. Patients were shown several photographs found in internet browsers, whose visual recognition was positive for a florwer called “Trumpet of the Angel”. Mydriasis relapsed spontaneously at 48 hours.

There are published a dozen published cases of unilateral mydriasis due to contact with plants, all caused by Brugmansia and Datura tree species. Both belong to the family of the Solanaceae, being this family the main one responsible for the intoxications by neurotoxins of botanical origin. The common toxin-producing species in our environment are Stramonium, nightshade (Tropanes); Tomatoe plant, Potatoe plant (Solanine); Petunia (Calisteginina), Pepper Chile plant (Calisteginine)

CONCLUSIONS

Unilateral spontaneous non reactive mydriasis and other systemic intoxications are frequently associated with contact or consume of anticholinergic toxins present in domestic gardening species. The question about the manipulation of plants during the anamnesis is key to its correct diagnosis. Common browsers make possible the visual identification 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #10883 - Mycoplasma pneumonia masquerading hospital acquired pneumonia complicated by watery diarrhea and shock.
Mycoplasma pneumonia masquerading hospital acquired pneumonia complicated by watery diarrhea and shock.

Introduction: Mycoplasma pneumoniae is a common pathogen for community acquired pneumonia. Due to its long incubation period, community acquired Mycoplasma pneumonia can manifest in the later course of the hospitalization, thereby masquerading hospital acquired pneumonia.

Case: A 91-year-old woman presented with fever, nausea, vomiting, diarrhea and abdominal pain. On day prior, she developed high fever, nausea, vomiting, abdominal pain and severe non-bloody watery diarrhea. On the day of presentation, she was brought to the emergency department because of the persistent symptoms. On examination, body temperature of 39.0 Celsius, blood pressure of 78/50 mmHg, and increased bowel sounds were appreciated. On laboratory, mild leukocytosis and elevated urea nitrogen and creatinine were observed. Chest X-ray and computed tomography without contrast were normal. She was diagnosed with acute infectious diarrhea complicated with shock and was admitted to the intensive care unit. Ceftriaxone and aggressive fluid resuscitation with noradrenalin was started. On day two, her blood pressure improved, and noradrenaline was tapered down and finally discontinued. On day three, fever and diarrhea resolved and ceftriaxone was discontinued based on the negative result of the blood, urine and stool cultures. However, she became febrile again and respiratory distress on the next day. Her chest CT showed airbronchogram in the right lower lobe. Aspiration pneumonia was suspected and she was started on intravenous ampicillin/sulbactam 1.5g every six hours. Despite the treatment, her condition did not improve even after the seventh day of admission. Mycoplasma pneumonia was suspected based on the prevalence at that time around the location of the hospital. Rapid antigen test for Mycoplasma was positive, suggesting the diagnosis of Mycoplasma pneumonia. Antibiotic was switched to doxycycline 100mg every twelve hour, and her fever and hypoxemia gradually improved. She was discharged on day 22 after completion of two weeks of doxycycline treatment.

Discussion: Mycoplasma pneumonia should be considered in hospitalized patients who is being hospitalized for more than 72 hours because the latent period of Mycoplasma pneumonia is longer than that period, as long as two to three weeks. Also, it should be listed as a differential diagnosis of aspiration pneumonia where Mycoplasma pneumoniae is endemic. The initial diarrhea complicated by shock might be attributed to the manifestation of Mycoplasma infection, potentially biased in making rapid diagnosis.


Yukinori HARADA (Mibu, Japan), Taku HARADA, Kohei MORINAGA, Takanobu HIROSAWA, Taro SHIMIZU
08:30 - 17:40 #11706 - Myocardial infarction in patient of 16 years without cardiovascular risk factors.
Myocardial infarction in patient of 16 years without cardiovascular risk factors.

16 year old woman patient, a nonsmoker with Antiphospholipid antibody syndrome and  Autoimmune Thrombocytopenic Purpura. She attends derived from review medical internal medicine by evidence on the electrocardiogram in V1-V3 ST Elevation. The patient concerned that 2 days ago consulted in emergencies by episode of crushing chest pain that is exacerbated with thoracic movements of 6 hours and that, after administration of metamizol IM relented, being diagnosed with muscle pain. From hospital discharge, the patient referred chest discomfort with physical effort.

Physical exam: Normotensive, 85 lpm. Sat 96%. Afebrile. Cardiopulmonary auscultation: Rhythmic tones without murmurs, decreased  vesicular murmur; Abdomen: globular, pitting blandoy, no masses or organ enlargement, blumberg Murphy -; MMII: no edema, no signs of DVT.

Complementary tests: Blood test showed:damage markers elevation myocardial CK-MMB: 116 and troponins: 14. Electrocardiogram: elevation of the ST V1-V3. Chest x-ray and echocardiogram: showed no significant findings. Cardiac catheterization: without Angiographically significant injuries. Patient enters plant of Cardiology with diagnosis of uncomplicated myopericarditis suspected for realization of cardiac resonance: infarction subendocardial in medial segment less likely related to arterial thrombosis.

Discussion: Antiphospholipid antibody syndrome (APS) is characterized by the association among arterial or venous thrombosis, recurrent pregnancy loss, thrombocytopenia and the presence of circulating antiphospholipid antibodies. Antiphospholipid antibody-related thrombosis seems to constitute a significant proportion of childhood thrombosisMany studies have demonstrated the diversity of clinical features associated with APS in children and teenagers including deep venous thrombosis, stroke, digital ischemia, pulmonary vasoocclusive disease and, more rarely, acute myocardial infarction. 


Carmen Adela YAGO (Malaga, Spain), Enrique CARO, María Del Carmen RODRIGUEZ, Valentina MORELL JIMÉNEZ, Juan Antonio RIVERO GUERRERO
08:30 - 17:40 #11701 - Myocardial injury in acute CO poisoning.
Myocardial injury in acute CO poisoning.

 

BACKGROUND

Carbon monoxide (CO), a highly toxic gas produced by incomplete combustion of hydrocarbons, is a relatively common cause of human injury.  Human toxicity is often overlooked because CO is tasteless and odorless and its clinical symptoms and signs are non specific. It is usually a  mass intoxication. In Tunisia, carbon monoxid exposure is the first cause of by poisoning . The heart may be severely affected after CO exposure with carboxyhemoglobin (COHb) levels exceeding 20%. 37% of patients exposed to CO will present an ischemic event. The 8 years cardiovascular related mortality is between 32 and 38%.

We report the case of three patients exposed accidentally to CO and presented  an acute coronary syndrome with and without  ST elevation .

CASE PRESENTATION

It is the case of three men with a mean age of 67, presenting to the emergency department  with headache, vertigo, drowsiness, digestive disorder, muscular weakness, altred mental status after exposure to a defective heating device. The CO poisonning was suspected and confirmation based on a HbCO level more than 35% ( 38-40%). The 3 patients recieved a normobaric oxygen therapy.

One patient developed an anginal chest pain and the electorcardiogram showed an ST elevation anterior myocardial infraction. The two others developed a NSTEMI without chest pain but cardiac biomarker ( troponin) elevation. An emergency coronary angiography revealed for the 3 patients tritroncular coronary significant stenosis. Coronary angioplasty with stenting and coronary bypass were performed depending on the severity of the lesions.

Left ventricular wall motion disorder was assessed by transthoracic echography. The mean of the left ventricular ejection function was 43%. The short term evolution was favorable.

CONCLUSION

 Myocardial injury is common in moderate to severe CO poisoning. A baseline ECG should be performed and serial biomarkers should be followed in all patients. Further study is needed to determine the long-term clinical significance of the myocardial injury as well as the efficacy of Hyperbaric oxygen therapy as adjunctive therapy for patients with myocardial injury resulting from CO poisoning.

 


Yousra GUETARI (Tunis, Tunisia), Dhekra HAMDI, Mounir HAGUI, Rim HAMMAMI, Bassem CHATRBI, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11952 - National Early Warning Score (NEWS) of 3 as a trigger for initiating sepsis screening tool for early identification of Sepsis in patients presenting to the Emergency Department: A Prospective Observational Study.
National Early Warning Score (NEWS) of 3 as a trigger for initiating sepsis screening tool for early identification of Sepsis in patients presenting to the Emergency Department: A Prospective Observational Study.

Sepsis is common and can potentially kill if the treatment is delayed. It costs lives and money. Early antibiotic administration has shown to improve patient outcomes, sometimes avoiding hospital admissions. Sepsis is a time critical condition so immediate recognition and appropriate treatment is the cornerstone of success. NEWS is currently used throughout NHS as an early warning system to identify acutely unwell patients.  Routinely a NEWS score of 4 would trigger sepsis screening.

The aim of this study was to use a NEWS score of 3 to trigger sepsis screening to help clinicians in early recognition and treatment of sepsis.

This was a prospective, single centre, observational study in a University Hospital Emergency Department that sees approximately 120,000 patients annually. All adults (>16 years) with acute presentation between August 2015 to February 2016 were included in the study. Sepsis proformas for all patients were collated and then ED records of patients with NEWS ≥3 were reviewed using Zylab (e-Discovery and information management system). We looked into the hospital notes of patients with a NEWS score of 3 to see if by using this score as a trigger for sepsis, we could identify sicker patients earlier. 


Dr Mahendra KAKOLLU (Swansea, ), Ranga MOTHUKURI
08:30 - 17:40 #11093 - Nephropathy for isolated use of NSAIDs.
Nephropathy for isolated use of NSAIDs.

Objective: Warning about possible consequences of NSAID use

Method: Patient of 20 years of Asian origin with history of hypertension, dyslilpemia and hypothyroidism not currently treated by own decision who comes to emergency room for increase of abdominal perimeter and both legs for two days without other accompanying symptomatology. Reports only catarrhal episode in previous days treated with AINEs. On arrival at the emergency department, the patient had high blood pressure (220/120mmHg) and physical examination revealed edemas with fovea in both legs and subcutaneous cellular edema. There is no objection to blows, scratches or crackling to auscultation. It does not present orthopnea. Complementary Test. In hemogram shows Renal Insufficiency (Creatinine 1,52mg/dl), Proteinuria (8,79 g/l). In EKG signs of left ventricular hypertrophy. Cardiomegaly in X-ray with heart in tent. Ultrasound of abdomen without disorders. Echocardiogram: Dilated and hypertrophic left ventricle with moderate / severe systolic dysfunction, associated pericardial effusion. Evolution:  In Nephrology department where the patient is,  he improves with deplective treatment, so that renal biopsy is ruled out and diagnosed of Negropathy by NSAIDs with severe secondary hypertension.

Conclusions: NSAIDs can produce nephrotoxic effects through several mechanisms, most of them related to hypoperfusion caused by renal vasoconstriction and mediated by inhibition of prostaglandins. It is important to consider the possibility of renal damage in patients with maintained consumption.


Teresa VALLE GIL, Rocio RODRIGUEZ BARRIOS (MALAGA, Spain), Laura GOMEZ RODRÍGUEZ
08:30 - 17:40 #11083 - NEUROLOGICAL IMPACT OF RENAL STENOSIS.
NEUROLOGICAL IMPACT OF RENAL STENOSIS.

47 year old woman, ex-smoker since 6 years 54 packs / year, high blood pressure (hypertension) diagnosed six weeks ago and treated with enalapril 10 mg every 24 hours. No family history of hypertension or cerebrovascular disease early are known. Go to emergency room for so sudden weakness in right hemisphere, language disorder and headache. Her blood pressure (BP) was 180/100 mm Hg and she was afebrile.

 

General and neurological examination showed confusion motor aphasia, right central facial paralysis, right hemiparesis (3/5 in the Medical Research Council scale), and hemisensory loss, right  Babinski´s reflex. National Institutes of Health Stroke Scale (NIHSS) score at presentation was 11. Cardiorespiratory auscultation and abdominal examination were normal.

Supplementary test showed brain hematoma on the computer tomography (CT) in the left underlying lymph  with intraventricular haemorrhage, perilesional edema and minimal midline deviation.

 

 

Different combinations of antihypertensive drugs were administered to control of BP.

 

Secondary hypertension was suspected because of the difficulty controlling BP, recent diagnosis with hypertension and severe organ damage. Cortisol, catecholamines and metanephrines in 24 hour urine were normal. Doppler ultrasound and CT angiography (Figure 1b) showed a critical proximal right renal artery stenosis without fibromuscular dysplasia.

A stent was placed by right renal angioplasty procedure. BP improved in the following weeks.

 

This case showes the neurological impact of a vasculo-renal pathology. Renal arthery stenosis is the second cause of secondary hypertension.

 

The stenting procedure was done because of the difficulty controlling BP. Currently, renal arterial stenosis angioplasty is is still under discussion. The Coral Study (Cardiovascular Outcomes in Renal Ateroclerotic Lesions) did not show cardiovascular or renal benefits between angioplasty  versus optimal medical therapy in ateroclerotic stenosis. On the other hand, angioplasy has shown a 2mmHg reduction in BP  without decrease in clinical event. Nowadays, angioplasty procedure should be undergone for those cases with failure of optimal medical therapy to control the BP; intolerance to optimal medical therapy; recurrent flash pulmonary edema and/or refractory heart failure and bilateral renal artery stenosis who have progressive renal insufficiency that is thought to be a result of the stenosis. 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11842 - NEUROLOGICAL INVOLVEMENT IN BEHCET’S DISEASE.
NEUROLOGICAL INVOLVEMENT IN BEHCET’S DISEASE.

neurological involvement in Behcet's disease


Ben Jazia AMIRA, Jaziri FATIMA, Maha BENNASR, Wafa SKOURI, Aloui ASMA (Tunis, Tunisia), Kouther ABDLGHNI, Turki SAMI
08:30 - 17:40 #11542 - Non blanching rash - an evolving picture?
Non blanching rash - an evolving picture?

Background: Non blanching rash (NBR) in children is a common presentation to our department and causes anxiety amongst clinicians and parents. There are a number of guidelines devised to help identify children with meningococcal disease (MCD).

Aim: To compare our departmental practice with recently validated guidelines: the Newcastle-Birmingham-Liverpool (NBL) algorithm (Riordan et al 2016)

Methods: Over a 3 month period the notes and results of all children presenting to our department who had haematology samples taken were evaluated. This identified all children who were bled as a consequence of attending with a NBR. The presentations, results and outcomes of these children were examined at least 3 months after they had attended.

Results: 124 patients were identified with NBR. 9 patients were admitted, 7 of these were treated with IV antibiotics; 1 had MCD, 2 E Coli UTI and the rest proven or presumed viral illness. No cases of serious bacterial illness were discharged without treatment. We did not have a high compliance with the NBL algorithm. If it had been followed there would have been an extra 47 children admitted for consideration of IV antibiotics.

Conclusion: The practice within our department does not comply with the recently validated NBR algorithm; however during this study period we have not missed children with MCD or serious bacterial infection. The cohort of children with NBR used to validate the NBL algorithm included 23% of children with confirmed or probable MCD at least 15 years ago. This suggests that our population of children presenting with NBR has changed and that in our setting, following NBL guidelines over treats a substantial number of children.


Louise RENNIE (Edinburgh, United Kingdom), Paul LEONARD
08:30 - 17:40 #11261 - Non-cardiac CT and the prevalence of calcification in patients with non-specific chest pain.
Non-cardiac CT and the prevalence of calcification in patients with non-specific chest pain.

Background:

20% of all patients seen in hospital with suspected Acute Coronary Syndrome will receive the diagnosis Acute Myocardial Infarction (MI). Not all of these patients with cardiovascular disease are identified by traditional risk factors such as cholesterol, hypertension, and diabetes or with conventional methods such as ECG, troponin and clinical symptoms. Non-Contrast Cardiac-CT measures the amount of calcification in the coronary arteries (CAC) and might be a useful addition in predicting future cardiac events in this patient group.

The aim of the present study was to first to investigate the prevalence of calcification measured by a non-contrast cardiac CT in an Emergency department ( ED) and Cardiology department (CD) population of patients with acute chest pain and no MI and compare the findings with the asymptomatic background population. Secondly to examine the frequency of cardiac events within the next 12 months in the non-specific chest pain ( NSCP) population and compare it to the prevalence of calcification the background population

Methods:

Subjects with the age 30-70 years and who were included in the study: "Identification of risk factors in non-specific chest pain patients" and a known risk factor for cardiovascular disease, were offered a non-contrast CT scan with calcium score after the hospital contact. The participants were included in a 12 months follow up, where the result of the calcium score was not revealed neither for the patient nor the investigator. After 12 months the results of the scan was compared with the rate of cardiac events. Furthermore the prevalence of calcification was compared with the Danish DanRisk study that investigated the prevalence of calcification in an asymptomatic background population.  This project is a multicenter study and recruited patients from 6 ED and CD in the region of Southern Denmark.

Endpoints were death related to medical conditions,, non-fatal myocardial infarction, coronary revascularization, and unstable angina.

Results

In total 230 patients were scanned. The median age was 57 yearswith 43% males. There were 2 outcomes during 12 months follow up (0.9%where two patients were re-vascularised. In the DanRisk population consisting of 1251 patients with 48% males had four events (0.3%): two with MI, one with ventricular tachycardia, and two died of which one was cardiac related.

The median CACs was 0 in DanRisk and 2 in the study population.  Male sex and age over 60 years, diabetes and hypertension were associated with increasing median CAC.  The prevalence of CAC(CAC>0)  was 54% in the study population and 46%in DanRisk with a p value=0.034. When adjusted for sex, age, diabetes, hypertension and hypercholesterolemia  no significance was found between the prevalence in the study population and DanRisk population.

Conclusion

Calcification degree in NSCP patients is not significantly higher than the background population. The event rate in NSCP group was very low. 


Nivethitha ILANGKOVAN, Pr Christian Backer MOGENSEN (Aabenraa, Denmark), Axel DIEDERICHSEN, Annmarie LASSEN, Hans MICKLEY
08:30 - 17:40 #11040 - Non-febrile syndromes in the traveler returning from tropical regions admitted in a monographic unit.
Non-febrile syndromes in the traveler returning from tropical regions admitted in a monographic unit.

Background. The aim was to analyse those syndromes without fever in travellers who return from tropical regions evaluated at our Department of Infectology and Tropical Medicine. Clarifying these condictions intends to reach earlier diagnoses and, perhaps, to avoid the emergence and spread of imported diseases, as well as to establish apropiate preventive measures.

Methods. An observational descriptive transversal study was performed, selecting those patients who returned from tropical regions without fever (n=281), amongst all travellers evaluated in our deparment between 1998 and 2013. We analysed demographic features, information related to the trip, as well as the presenting complaints and the diagnoses.

Results. A total of 281 international travellers presenting without fever were analysed. Only 39% had received health counsel prior to travelling. The most visited regions were Latin America (38.8%), Africa (37.8%) and Asia (13.6%). 15% of patients were asymptomatic of suffered from non-infectious conditions. Among the rest, most had either gastrointestinal (46%) or cutaneous ( 38%) syndromes. The main gastrointestinal condition was diarrhoea, with a microbiological diagnosis reached in almost 50% of cases. Regarding cutaneous syndromes, artropods bites (31%) and different bacterial lesions (20%) were most common.

Conclusions. Aproximately 10% of patients in Travel Medicine are international travellers returning from tropical regions, half of them with no fever. Most are diagnosed with infectious diseases, mainly gastrintestinal or cutneous syndromes. Eosinophilia is the third problem in frequency among this group of patients, and sexually transmitted infections are rare in our cohort. It is important to emphasize in preventive activities.


Barbara MARTIN GINER, Barbara MARTIN GINER (MADRID, Spain), Jose Luis PEREZ ARELLANO
08:30 - 17:40 #11050 - Non-histaminergic angioedema in the emergency room. About a case.
Non-histaminergic angioedema in the emergency room. About a case.

CLINIC HISTORY

A 27-year-old woman with a personal history: Varicella at age 10. In usual treatment with oral contraceptives. The family history was: father with hereditary angioedema with C1 inhibitor deficit. She went to the emergency room due to her edema of lip and tongue of 2 hours of evolution, not pruriginous, previously had not presented similar episodes. Today they had a dental cleaning done. Deny fever, no dyspnea, no voice changes, no abdominal pain or diarrhea. Physical examination: Blood pressure of 130/78 mmHg, heart rate of 90 bpm, Sat O2 98% respiratory rate 12 rpm. Weight 67 kg Head and neck: non-erythematous upper lip angioedema, well delimited, non-pruritic, not painful on palpation and angioedema of predominantly right non-painful or erythematous right. Cardiopulmonary auscultation, abdomen and neurological examination: normal.


EVOLUTION AND TREATMENT

After the initial evaluation we determined treatment with:

• Methylprednisolone 60 mg IV.

• Deslorpheniramine 5 mg IV.

• Adrenaline 1 mg IM.

 

After which no response was obtained, and treatment with tranexamic acid 1 gram intravenously was initiated, although clinical manifestations remained unchanged.

Finally, it was decided to give Firazyr® (Icatibant Acetate) 30 mg subcutaneously in the abdominal region, giving the episode completely in less than 45 minutes.

The patient remained monitored for 12 hours in the emergency room and was discharged to the Allergology office to complete the study.

 

CONCLUSIONS

In the case of angioedema in the emergency room, the distinction between non-bradykinin and bradykinin angioedema is crucial, since in the latter the usual treatment with antihistamines, corticosteroids and adrenaline is usually ineffective and the early establishment of specific treatment especially if it is a severe crisis.In cases of peripheral angioedema without involvement of other locations, the patient will be kept on observation for 2-6 hours after symptom resolution begins. If angioedema occurs in the context of anaphylaxis, a monitoring of 6-12 hours is recommended, and if there has been a cardiovascular compromise, monitoring for 12-24 hours is recommended because of the possibility of a biphasic reaction, which occurs up to one 20% of cases. Upon discharge from the Emergency Department, the patient will be referred to the Allergy Service to carry out the relevant study.

 

 


Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO, David NUÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11985 - Non-Technical Skills improvement during a training program based on High-fidelity simulation.
Non-Technical Skills improvement during a training program based on High-fidelity simulation.

Aim: Emergency Medicine represents a high-risk setting where the correct application of Crisis Resource Management (CRM) principles can improve  patients care. Failures in teamwork make a substantial contribution to suboptimal care and Non Technical Skills (NTS) training is increasingly employed in simulation and real world to improve patients safety. This study is a preliminary evaluation of the effectiveness of a training program with high-fidelity simulation in improving Technical (TS) and Non-Technical skills (NTS) of residents in Emergency Medicine.

Methods: We realized 5 simulation sessions based on patient management in critical situations, each including 4 scenarios. At the beginning of the training program, all participants also received an introductive presentation of CRM principles. Every session covered a different topic in Emergency Medicine Curriculum (Shock; Allergy; Environmental Emergencies; Sepsis; Breaking bad news) and was preceded by an introductive lecture. Two groups (6 residents per group) of II-III years residents in Emergency Medicine joined separately each session and performed all scenarios; we therefore examined TS and NTS from 8 scenarios in each session. A trained observer rated TS and NTS at the end of each scenario. TS were measured as percentage of critical actions correctly performed by participants; NTS were rated by mean of Clinical Teamwork Scale (CTS). Non-parametric Friedman test and Spearman correlation analysis were employed to measure variation of TS and NTS through following sessions and correlation of TS and NTS.

Results: Overall CTS score (from Session 1 to Session 5: 53±14, 5753±1412, 63±9, 70±9, 88±7, p=0.001) as well as Communication (11±2, 13±3, 12±2, 14±2, 21±2, p=0.001), Situational Awareness (4±1, 5±1, 5±1, 6±1, 8±1, p=0.001) and Role Responsibility (9±3, 8±2, 10±2, 13±2, 13±2, p=0.001) subscores,  increased significantly through following sessions. Percentage of correctly performed TS increased in a non significant way (63±24%, 78±26%, 65±17%, 85±10, 86±16%, p=NS); if we compared the first and the last session, the difference in accomplished TS was only tendentially significant (p=0.059). All subscores showed a high correlation coefficient with the global CTS score: 0.816 for Communication, 0.879 for Role Responsibility and 0.942 for Situational Awareness (all p<0.001). On the other side, the percentage of performed TS showed a moderate correlation both with CTS score (0.485, p=0.001) and with different subscores (Communication 0.501, p=0.001; Situational Awareness 0.648, p<0.001; Role Responsibility 0.321, p=0.043).

Conclusions: High-fidelity simulation has proven to be an effective instrument to improve NTS among Emergency Medicine residents. Effectiveness on the TS improvement was not significant, but this result could be influenced by the fact that every session covered a different topic and required different knowledges.


Caterina GRIFONI, Chiara DONNINI (SESTO FIORENTINO-FIRENZE, ), Alessandro BECUCCI, Irene TASSINARI, Roberto GIANNI, Francesca INNOCENTI, Riccardo PINI
08:30 - 17:40 #11514 - Non-Technical Skills, a grid for safety in emergency: developing an objective evaluation tool for emergency physician.
Non-Technical Skills, a grid for safety in emergency: developing an objective evaluation tool for emergency physician.

The World of Health suffered the "security emergency" shock following the report "To Err is Human", in which many medical mistakes, more or less consciously committed, were described.

The technical skills of a single professional are not enough to prevent errors: it is impossible to reset the human factor, responsible for 80% of errors. Thus, there is an urgent need to train and evaluate professionals as well as on technical components, including those skills of leadership, situation awareness, decision making, teamwork, communication that are relevant in non-technical skills field.

Among the areas at high risk of error there is the Emergency Department which in fact has uncertainties, unpredictability, temporal tension, so much so that Emergency is defined as a "natural environment for error study."

In our Training Center, a group of Emergency Physicians and Nurses, trained and coordinated by two external counselors, Commanders and NTS Aviation Trainers, developed an NTS assessment grid for the ED, identifying specific  behavioral indicators. The grid is an objective evaluation tool that leaves no possibility for subjective judgment. Staff rating through grid highlights potential NTS defects and suggests the training goals needsd to create an efficient, team, increasing the awareness of a culture of security in a high-risk work environment such as Emergency Department


Lucia ANTOLINI, Chiara BOVO (VERONA, Italy), Giorgio RICCI, Massimo ZANNONI
08:30 - 17:40 #11761 - Nosocomial transmission of clostridium butyricum type E responsible for two cases (one outbreak) of infant botulism.
Nosocomial transmission of clostridium butyricum type E responsible for two cases (one outbreak) of infant botulism.

Objective: Botulism may develop if a preformed toxin is ingested or if clostridia producing botulinum neurotoxins grows in the intestines or wounds, and toxin is released. Person-to-person transmission does not occur and poisoned patient not required isolation. We reported two cases (one outbreak) of nosocomial transmitted infant botulism (IB). Case series: Case 1: A 12-week-old infant (5 Kg bw) was admitted to the ICU because of feeding difficulties, weak cry, poor head control, mydriasis, generalized weakness, hypotonia, and acute/tympanic abdomen. The mother reported the presence of stypsis associated with abdominal colic (from 2 weeks) unsuccessfully treated with cimetropium bromide. Due to the rapid neurological worsening with a floppy-baby hallmark, IB was suspected. Lab-tests confirmed type E botulism. Considering the serious conditions, the patient was intubated, treated with antitoxin and, subsequently, with clostridiocidal antibiotic (metronidazole) and PEG-4000 whole bowel irrigation by gavage. Clinical conditions progressively improved and the infant was transferred, 5 days after antitoxin administration, in the paediatric ward. Faeces resulted negative 12 days after antibiotic treatment. Case 2: An 8-week-old infant hospitalized from birth in the same ICU, presented a clinical picture of botulism 15 days after the case-1 admission. This baby was born at 26th weeks of gestation with a birth weight of 679 grams. During hospitalisation received supplemented human milk, D-vitamin, probiotics and caffeine. Laboratory investigation confirmed also for this patient type E botulism. The patient was intubated and supported in the respiratory function, and treated with antidote and antibiotic. Clinical conditions gradually improved with complete return to spontaneous respiration 7 days after antitoxin administration. He excreted C. butyricum type E from faeces for 15 days. Whole Genome Sequencing revealed that C. butyricum type E isolated from the specimens of the 2 patients were indistinguishable. No C. butyricum type E was detected in the ICU environmental samples collected after that the second case was confirmed by laboratory investigations. Conclusions: We report the first description of nosocomial transmission of C. butyricum type E responsible for two cases of IB: the two families and the two patients came from different geographical areas and never had any contact previously. Although isolation of these patients is not necessary, particular care should be taken to avoid nosocomial transmission of spores. The same procedures adopted to prevent nosocomial transmission of Clostridium difficile colitis could be successful implemented to reduce spreading of neurotoxins producing clostridia spores.


Valeria Margherita PETROLINI, Davide LONATI (PAVIA, Italy), Marta CREVANI, Bruna AURICCHIO, Mara GARBI, Fabrizio ANNIBALLI, Carlo Alessandro LOCATELLI
08:30 - 17:40 #11431 - Not!!Another pregnant who vomits...
Not!!Another pregnant who vomits...

37-year-old pregnant woman(35weeks+4days gestation) was admitted to the emergency department for a 2week history of vomiting. Weakness since 2days ago. No diarrhea. No fever. She had no complaints of abdominal pain, leaking or bleeding per vaginum or decreased fetal movement. Her pregnancy had been uncomplicated.This was the third time that patient consulted for the same symptoms. She was taking doxylamine succinate without improvement in her development.

On examination she was conscious, oriented, cooperative and responding appropriately to verbal commands. The patient was well hydrated and afebrile. Her blood pressure was 123/83 mm Hg, pulse rate was 95 per min and glucose was 151mg/dl. She had icterus but not edema. Her cardiovascular and respiratory systems were normal. Abdominal examination revealed relaxed uterus of 35weeks size, with fetus in cephalic presentation and normal fetal heart rate. On vaginal examination, it was closed and cervix uneffaced.

Test revealed:hemoglobin of 13.7g/dl, leucocyte count of 9440/mm3,platelet count 424/uL. Liver function test: serum bilirubin of 3.16mg/dl, alanine aminotransferase 1562IU/l, aspartate aminotransferase 1236IU/l. Kidney function tests:blood urea 63mg/dl, serum creatinine 2.29mg/dl. The coagulation profile showed prothrombin time 52 seconds, with INR 5.7. Ultrasound abdomen showed normal liver and other organs.

Upon suspicion of gestational fatty liver, it was decided to enter an intensive care unit for supportive management. Six hours after admission, the patient presented  poor clinical and analytical evolution, so, they decided to perform cesarean and intensify treatment, improving in her development in a couple of days.

 In pregnancy, pathological conditions causing abnormality of liver function tests need to be differentiated from normal physiologic changes. Among various causes of pathological hepatic dysfunction, acute fatty liver of pregnancy (AFLP) is uncommon compared to pre-eclampsia.AFLP is a life threatening obstetric emergency. It usually occurs in the third trimester or post-partum period. There is predilection for nulliparous women, women with multiple gestation and pregnancies with male fetus. The most common presentation is malaise, nausea, vomiting and epigastric pain followed by jaundice. Due to high maternal and perinatal mortality, early diagnosis, prompt delivery and supportive care are required.

Laboratory tests usually demonstrate high bilirubin levels, deranged liver and renal functions, coagulopathy and hypoglycaemia. Liver biopsy is the gold standard for diagnosing, but due to the presence of coagulation abnormalities diagnosis is usually made by clinical and laboratory findings. Bleeding and disseminated intravascular coagulation are one of most common complications.Management of AFLP include of rapid delivery of the fetus and supportive care.Early diagnosis, prompt delivery, adequate supportive care, and a multidisciplinary approach are the key to a good outcome.


Marta MERLO (MADRID, Spain), Patricia BAZÁN, Juan LUQUE, César VERGARA, Elena AZNAR, Virginia ÁLVAREZ, Raquel CASERO, Francisco SALAS
08:30 - 17:40 #11275 - Novel oral anticoagulants withdrawal-induced acute renal infarction mimicking appendicitis.
Novel oral anticoagulants withdrawal-induced acute renal infarction mimicking appendicitis.

Purpose of the study: Acute renal infarction (ARI) is a rare cause of referral to the emergency department (ED). The two major causes of ARI are: thromboemboli, originating from a thrombus in the heart or aorta, and in-situ thrombosis, causing complete occlusion of the main renal artery or a segmental branch artery. Clinical diagnosis of ARI is frequently missed or delayed, because patients commonly present with symptoms mimicking other, more common conditions, such as nephrolithiasis, urinary tract infection, and appendicitis. We report a case of ARI, with ambiguous presentation of appendicitis, in a patient after abrupt discontinuation of novel oral anticoagulants (NOAC). Case report: A 63-year-old female presented to our ED with acute right-sided flank pain, radiating to the back. Physical examination revealed tenderness to palpation in right lower quadrant of the abdomen. The patients’ medical history exposed presence of persistent atrial fibrillation (AF). The patient acknowledged withdrawal from NOAC rivaroxaban, for the time period of ten days, due to severe nausea. Apart from mild leukocytosis and elevated levels of lactate dehydrogenase, laboratory results and urinalysis were unremarkable. Trans-abdominal ultrasound (US) examination ruled in possible right-sided nephrolithiasis. Non-contrast computed tomography (CT) scan of the abdomen demonstrated abnormally thickened appendix, with surrounding inflammatory changes. Hence, the patient was scheduled for emergency surgery. After general anaesthesia induction, a fast form of AF was documented. Despite antiarrhythmic therapy, hemodynamic instability was profound, and the patient underwent cardiac arrest (CA). After 45 minutes of advanced-life-support measures being performed, the return of spontaneous circulation occurred. Surgery procedure was postponed, and the patient was transferred to the Intensive Care Unit. Contrast enhanced CT scan of the abdomen showed extensive infarction involving lateral upper and lower pole of the right kidney, due to visible emboli in right renal artery. Post-CA trans-thoracic US indicated tachycardia-induced cardiomyopathy, with EF of only 20%. Although an intra-cardiac thrombus was not identified, the presence of AF and a structurally abnormal heart make this the likely source of her renal embolism. Considering the suspected duration of ARI, the treatment included low molecular weight heparin. Follow up trans-abdominal US examinations demonstrated right kidney hypofunction. Three weeks after CA the patient was discharged, without any neurological impairment, instituting new NOAC therapy with apixaban. Conclusion: In the ED, due to a vague clinical presentation, resembling more frequent abdominal pain disorders, diagnosis for ARI is very challenging. We highlight the importance of strongly considering ARI in patients presented with the following triad: (1) persistent abdominal and/or flank pain, (2) elevated serum LDH, and (3) risk of thromboembolic event.


Dr Dinka LULIC (Zagreb, Croatia), Mirjana MIRIC, Ileana LULIC
08:30 - 17:40 #11213 - Nutritional status of patients under vitamin K antagonist with major bleeding. A case–control study.
Nutritional status of patients under vitamin K antagonist with major bleeding. A case–control study.

Introduction: The annual incidence of major bleeding related to Vitamin K Antagonist (VKA) is around 10% and fatal bleeding about 1%. Many factors were associated with a bleeding risk. However, if patients related risk factors or genetic risk factor were well studied, the impact of the nutritional status on the bleeding risk have not been identified yet. The aim of this study was to assess the nutritional status and micronutrient status of patient under VKA with major bleeding and those without.

Methods: We conducted a monocentric, case-control study in our university hospital (Clinical trials: NCT 01742871). The patients were divided into two matched groups for sex, age and INR rate: the case group with major bleeding related to VKA and the control group without major bleeding. Malnutrition was defined as a loss of weight (> 5% during one month or > 10% during 6 months), a body mass index < 21, serum concentrations of albumin < 35 g/l and a Mini Nutritional Assessment < 17. Severe malnutrition was defined as a loss of weight (> 10% during one month or > 15% during 6 months), a body mass index < 18, serum concentrations of albumin< 30 g/l.

Results: From August 2012 to October 2015, 98 cases and 196 controls were included. The sex ratio (Male/Female) was 0.72 for both. The mean age was 82.2+/-7.9 for the case and 81.7+/-7.9 for the control group without statistical difference. The mean INR rate wasn’t statistically different between the both group with, respectively, 4.6+/-2.5 and 4.3+/-2.2. As expected, the case group was more likely to have a history of major bleeding than the control group (respectively, 23% vs. 10%, p=0.004) without difference for renal insufficiency, stroke, cardiac insufficiency or myocardial infarct. Malnutrition was found in 77% of the case group and in 64% of the control group (p=0.027). Severe malnutrition was two fold higher in the case group than in the control group (respectively, 45% vs. 23%, p < 0.001). However, the mean BMI wasn’t different between the two group (respectively, 26.4+/-5.0 vs. 27.5+/-5.7). Interestingly, regarding the micronutrient status, plasmatic zinc was lower in the case group than in the control group (respectively, 9.9+/-5.6 vs. 10.5+/-3.8, p=0.03) whereas plasmatic copper or vitamin C or vitamin B1 weren’t statistically different.

Conclusion: Our study showed that patient with major bleeding related to VKA were more likely to suffer from malnutrition than those under VKA without bleeding with a two-fold higher rate of severe malnutrition in those with major bleeding. Moreover, the plasmatic zinc seemed to be lower in those with bleeding than in those without. Physicians must be aware that nutritional status must be taken into account when they introduce VKA therapy.


Farès MOUSTAFA (Clermont-Ferrand), Loic DOPEUX, Aurélien MULLIEZ, Yves BOIRIE, Régine QUINARD, Damien RICHARD, Rémi ESPENEL, Jeannot SCHMIDT
08:30 - 17:40 #11778 - Obstetrics and Gynecology Emergency Care at Women’s hospital, Doha, Qatar - A Novel approach to care through an Innovative Emergency department.
Obstetrics and Gynecology Emergency Care at Women’s hospital, Doha, Qatar - A Novel approach to care through an Innovative Emergency department.

Introduction

Worldwide 15% of all births result in life threatening complications during pregnancy. In 1997 the WHO and UNICEF introduced the concept of Emergency Obstetric and Newborn care and in September 2000 the UN committed to reaching the Millennium Development Goals of a three quarter reduction in the maternal mortality ratio. The WHO concludes that in order to do this, Emergency Obstetric Care must be available and accessible to all women.

The Women’s Hospital had approximately 16,000 deliveries in 2016 and the numbers continue to rise due to high fertility rates and an influx of women of child bearing age in the expatriate population. Our dedicated Obstetrics & Gynecology (OBGYN) Emergency Department(ED) has over 70,000 visits a year and is one of the largest known facilities in the worlds catering solely for OBGYN Emergencies. This has led to a need for an innovative approach to the delivery of Emergency OBGYN women’s care in Qatar. We present the results of a 5 year improvement project.

Methods

The concept of an ED dedicated solely to women is relatively new with few hospitals in North America and worldwide having one. The aim of the project was to improve morbidity and mortality and to provide safe, efficient and high quality care to our women.

TheED has been adapted and modified to suit the local population need and is led by Consultant Obstetrician and Gynecologists. Patients are seen by highly trained OBGYN physicians at their first point of contact. TheCanadian Emergency Department Triage and Acuity Scale is used to triage patients and a case mixture of both acute and non-urgent cases are seen. A total care of package is provided including Consultation, full investigation and treatment with rapid access to Theatres, Labor room, High dependency unit or admitting wards. Women can self-refer and the ED is often the 1st point of contact for many pregnant or acute Gynecology cases.

Results

Ratio of Obstetrics to Gynecology cases is 3 to 1. Of acuity 1 patients 100% are seen within 5 minutes of arrival and 96% of acuity 2 cases are seen within 15 minutes with a total length of stay of less than 2 hours in 73 %. Quality and safety measures include the innovative “Fast track system” which was successfully introduced to ensure women presenting with low acuity conditions were seen within 2 hours or less. Key performance indexes include: numbers of patients leaving without being seen, numbers returning within 48 hours for same condition and Quarterly patient satisfaction rate among others. This has transformed delivery of care with over 84% satisfaction rates.

 

Conclusion

We believe that we have a unique and hugely successful approach to delivery of Emergency care in OBGYN. The population of Qatar has more than quadrupled in the last 15 years and this has necessitated improvement and innovation in services. Qatar is developing a comprehensive program that targets the health challenges unique to women and the OBGYN ED project is at the forefront of this.


Huda SALEH (Doha, Qatar), Zeena AL MANSOORI, Alia SEROUR, Justin KONJE, Gbemisola OKUNOYE, Olubunmi ONIYA
08:30 - 17:40 #10923 - Old woman and recurrent abdominal pain, usefulness of point of care ultrasound.
Old woman and recurrent abdominal pain, usefulness of point of care ultrasound.

Purpose: Gallbladder cancer (GC), is the most common biliary tract malignancy, representing 3% of malignant tumors, and has a high mortality, mainly related regional spread. Early detection remains difficult, and is often casual. We present a case of GC, diagnosed at emergency department, through the use of ultrasound scanning used by emergency physicians.

Material & Methods: a patient with abdominal pain, with a final diagnosis of a GC

Results: 81 year old woman, was admitted to the emergency room after several consultations at its health center by right upper quadrant pain of several weeks duration, accompanied by fatigue, weight loss and a feeling of abdominal distention. On examination he had preserved the vital signs and had only found tenderness in the right upper quadrant, without signs of peritoneal irritation. Analytical emergency were unremarkable. Given the persistence of pain the emergency physician made an ultrasound scanning observing a large mass occupying the gallbladder bed, hypoechoic lesions in liver parenchyma, and perihepatic free fluid.

Conclusion: most are adenocarcinomas (95-98%). The histological type with better survival is papillary adenocarcinoma. Produce liver metastases from expansion angiolymphatic own areas of direct hepatic infiltration. The presenting symptoms are nonspecific and difficult to differentiate from other more prevalent diseases such as biliary colic or chronic cholecystitis. The most common symptom is pain in right upper quadrant dull and aching. When symptoms such as jaundice or other constitutional symptoms usually appear advanced. Ultrasonography is the method of initial diagnosis image, and when it is diagnosed in early stages is usually discovered incidentally by ultrasound for another reason, which can observe a large mass occupying the gallbladder bed with wall thickening. Furthermore, ultrasound is very sensitive for detecting dilatation of intra/extrahepatic bile duct and the presence of hepatic metastatic lesions or direct infiltration of the parenchyma.


Alberto Ángel OVIEDO GARCÍA (DOS HERMANAS (SEVILLA), Spain), Francisco LUQUE SÁNCHEZ, Margarita ALGABA MONTES
08:30 - 17:40 #11577 - Oligoanalgesia in emergency medicine- a practical approach.
Oligoanalgesia in emergency medicine- a practical approach.

Background. Oligoanalgesia is still a problem in emergency medicine, with pain being under-optimal treated in the Emergency Department. Changing ED attitudes about pain assessment and management requires attention and continued research in the field. We aim to evaluate current medical practice in the management of analgesics in ED situations not included in current guidelines.

Method: A prospective, informed study (informed consent) was conducted between August and November 2016. Patients was admitted in ED with self-assessed pain level of 3 or 4/4 on the Verbal rating scale for pain (VRS), with urgent and standard pathology, and received analgesic treatment with: paracetamol (WHO class I), tramadol (WHO class II) and fentanyl (WHO class III). We analyzed the profile of ED patients receiving analgesia, the analgesia regimens used in ED and the analgesia efficiency. Patients were evaluated, monitored and treated according to internal protocols for the pain-causing conditions. Evaluation of pre- and post-therapeutic pain was done using the VRS scale (no pain=1, mild=2, moderate=3, severe=4), applied at the time of the first assessment by the emergency physician and after treatment.

Results: The study group included 121 patients, 44, 6% women and 55.4% men, with an average age of 52.75. All patients were stable hemodynamic: blood pressure average 143/83 mmHg, heart rate between 64 and 112 / min (average 84.43 / min). Pain first evaluation at ED admission was VRS=4 for 92,5 % of male patients and 90.6% for female patients. 62.6% received paracetamol (1 g i.v.), 25.8% tramadol (100 mg iv / i.m) and 11.6% fentanyl (1-2 dose of 50 mcg i.v.) All patients initially receiving fentanyl had a VRS 4 pain level. Adverse reactions only appeared to opioid-treated patients (9.3% of women and 7.3% of men experienced nausea, vomiting, headache, dizziness). The pathology that generated the pain: 12.4% multiple contusions by falling from the same level, 11.6% by fall from the height, 14% abdominal pain, 14% renal colic, 10% neuralgia intercostal, 10% limb fractures and the rest non-traumatic osteo-articular pathology.

Tramadol was administered to 93.3% of patients with pain level of VRS = 4. Post- treatment pain levels of 2 or 1 were obtained in 50% of them. After the first administration of fentanyl the pain decreased to VRS = 1 to 41.4% of the patients and VRS = 2 to 24.2% of patients. Repeated titration doses of fentanyl (between 2-5x50 mcg) were needed in 29.8% of subjects with initial pain after the first analgesic dose, with a reduction in pain of level 2 (39%) or 1 (27.8%) of them.

Conclusions: Analgesia remains a problem for emergency services, given the patients' wide pathology, the pain threshold and, last but not least, their anxiety. The decrease in pain level was obtained in more than half of patients after the first dose of analgesic. Tramadol and fentanyl were the most used and most effective antalgics, being used as first intention or after paracetamol.


Viorica POPA-OHRIAC, Diana CIMPOESU (IASI, Romania), Ovidiu Tudor POPA, Gabriela GRIGORAS, Elena BUTNARU
08:30 - 17:40 #11145 - Opening the floodgates.
Opening the floodgates.

Introduction-Cerebral hyperperfusion is a rare, but serious, complication following revascularization. Hyperperfusion is a 100% or greater increase in CBF compared with baseline. This definition also extends to rapid restoration of normal perfusion pressure, for example, with thrombolytic therapy for acute ischemic stroke. Reperfusion syndrome can occur as a complication of carotid endarterectomy (CEA), intracranial stenting, and even bland cerebral infarction. The prognosis following hemorrhagic transformation is poor. Mortality in such cases is 36-63%, and 80% of survivors have significant morbidity.

Case Report-A 78 years male hypertensive, diabetic and known coronary artery disease patient came to emergency department with complain of weakness in left upper limb since 4hours which was progressively improving without slurring of speech, leg weakness, palpitation or loss of consciousness. On arrival patient was conscious and oriented with normal vital parameters and normal blood glucose level. On examination patient was having left upper limb power 4/5. Other than that neurological and systemic examination was normal. Patient was undergone basic blood test and Magnetic Resonance Imaging(MRI) of brain which was suggestive of small acute infarct in right high fronto-parietal region. Patient was treated with dual antiplatelets and supportive measures. On carotid doppler patient was found to have 90% obstruction of internal carotid artery on right side and 60% on left side. Patient was opted for digital subtracted angiography(DSA) and angioplasty of right internal carotid artery. After the successful completion of procedure patient became progressively drowsy and developed left upper limb and lower limb dense hemiplegia. To rule out intracranial hemorrhage immediately computed tomography(CT) of brain was performed and which was suggestive of hyperdense fingerlike projection were noted in sulci all over right side of brain. Differential diagnosis of subarachnoid hemorrhage and hyperperfusion syndrome was suspected. Subsequent computed tomography of brain was suggestive of no hyperdense projections after 24 hours conforming the hyperperfusion syndrome. Patient was treated conservatively and improved in 15 days and discharge home with left hemiparesis.

Disscussion- An abrupt increase in cerebral blood flow following revascularization has been identified as the direct physiological cause of hyperperfusion syndrome. Several factors including advanced age, underlying leukoaraiosis, and postprocedural high blood pressure have been associated with this condition.  Two interlinked and synergistic mechanisms may lead to development of syndrome; impaired cerebral autoregulation and postoperatively elevated systemic blood pressure. If not treated properly, it can result in severe brain oedema, intracerebral hemorrhage, or death. Treatment strategies are directed towards regulation of blood pressure and limitation of rises in cerebral perfusion.


Dr Ketan PATEL (Ahmedabad, India), Anjali PATEL, Rignesh PATEL
08:30 - 17:40 #11141 - Optimal quantity of opioid to prescribe for acute pain to limit misuse after emergency department discharge.
Optimal quantity of opioid to prescribe for acute pain to limit misuse after emergency department discharge.

Introduction: A 2008 survey found that 1.9% of the entire US population was using prescription pain medication non-medically and that 56% obtained them from a friend or relatives. Diversion of pain medication may occur when a portion of the prescription is unused for pain relief after an ED visit. We hypothesized that at least 10 pills (~40%) of an opioid prescription 2 weeks after an ED visit, will not be consumed and become available for potential misuse.

 

Objective: Determine the quantity of unused opioids pills for common acute pain diagnoses, 2 weeks after an ED visit for acute pain.

 

Methods: Prospective observational cohort study of consecutive ED patients from a tertiary academic urban hospital with 60,000 ED visits annually. Inclusion criteria: aged ≥18 years, acute pain conditions present ≤2 weeks, pain intensity at triage of ≥ 4 (on a 0-10 numeric rating scale; NRS), and discharged with a new opioid prescription. ED physicians identified (24/7) eligible patients. They recorded the pain complaint/location, the final diagnosis, the quantity and type of prescribed pain medication. Discharged patients completed paper or electronic 14-day diary (REDCap database) to document their pain medication consumption. As a mitigation strategy, they were also contacted by phone at 2 weeks for the same information. A paired t-test was used to test the difference between the amounts of opioids prescribed and consumed.

 

Results: 447 patients were recruited. Mean age 50 (SD ±16) and 51% were men. Painful diagnosis: fracture (18.3%), acute back pain (16.7%), renal colic (16.5%), Contusion (8.6%), Sprain (excluding back/neck pain) (5.4%), abdominal pain (4.5%), acute neck pain (4.8%), and other (24.2%). Opioids prescribed: oxycodone (43%), morphine (41%) and hydromorphone (15%). Means quantity of opioid pills prescribe: 24 (IC95%: 23-26). Filled opioid prescription: 94%. Means quantity of opioid pills consumed: 8.8 (IC95%: 7-9). Means quantity of unused opioids pills: 15. Opioid pills available for misuse in our cohort: 6,705 pills.

 

Conclusions: After an ED visit for acute pain a significant portion of opioids prescribed is unused and available for misuse. A large pragmatic study should be done to confirm that an opioid prescription strategy based on our results will limit unused opioid pills while maintaining pain relief.


Raoul DAOUST, Jean PAQUET, Eric PIETTE, Judy MORRIS (Montréal, Canada), Alexis COURNOYER, Gilles LAVIGNE, Sophie GOSSELIN, Jacques LEE, Marcel EMOND, Jean-Marc CHAUNY
08:30 - 17:40 #11884 - Optimization of basal pharmacological treatment in the emergency department on discharge in patients with decompensated atrial fibrillation.
Optimization of basal pharmacological treatment in the emergency department on discharge in patients with decompensated atrial fibrillation.

Introduction

Atrial fibrillation is the most frequent sustained arrhythmia. It appears in all ages, being more frequent in the elderly. It is associated with an important morbimortalid in the form of stroke, thromboembolism and heart failure The treatment is focused on the prevention of the thromboembolic phenomena , control of the frequency and cardiac rhythm.

Objective

To evaluate in patients with previous diagnosis of atrial fibrillation the optimization of pharmacological domiciliary treatment (control frequency and cardiac rhythm) on discharge from the emergency department after an episode of decompensation.

 Material and methods

Observational, retrospective study in a General Hospital with an area of 200,000 inhabitants and 275 urg / day. Patients with diagnosis of discharge from atrial fibrillation who attended between October 2012 and December 2013 were included. The pharmacological treatment at home (frequency control and cardiac rhythm) and the treatment on discharge of the emergency department in patients with previous atrial fibrillation who consulted in emergencies with decompensation. Data analysis was performed using the SPSS statistical program.

 Results

   They consulted 762 AF patients, of whom 322 had previous diagnosis of atrial fibrillation.

 The home treatment was: Non-dihydropyridine calcium antagonists 62 (19.25%); Digoxin 32 (9.9%), Amiodarone 29 (9%), Flecainide38 (11.8%), Dronedarone 16 (4%) and Diltiazem 49 (15.22%), (4.95%), Propafenone 2 (0.62%), Sotalol 1 (0.3%) and other 2 (0.6%)

 The treatment of post-decompensated emergencies was: Non-dihydropyridine calcium antagonists 65 (20.19%), Beta-123 blockers (38.20%), Digoxin 39 (12.11%), Amiodarone 16 (4.97%), Flecainide 55 (17.1%), Dronedarone 22 (6.83%), Propafenone 2 (0.62%), and sotalol 1 (0.31%).

 Conclusions

Regarding the non-dihydropyridine calcium antagonists, Digoxin and Dronedarone, no significant changes were observed although they were prescribed slightly higher than the previous treatment at home.

There was also a slight decrease in the use of beta-blockers and amiodarone at discharge with an increase in the use of flecainide at 5.3% at discharge compared to previous treatment.

There were no changes in the use of Propafenone and sotalol


Maria CORCOLES VERGARA, Danae FERNANDEZ-CAMACHO, Blanca DE LA VILLA ZAMORA, Nuria RODRIGUEZ GARCIA, Maria Jose MARTINEZ VALERO, Maria Consuelo QUESADA MARTINEZ, Blanca MEDINA TOVAR, Pascual PIÑERA SALMERÓN (montepinar, Spain)
08:30 - 17:40 #11607 - ORAL ANTICOAGULANT REVERSAL STRATEGIES IN PATIENTS WITH MILD TRAUMATIC BRAIN INJURYINTRODUCTION: Traumatic brain Injury (TBI) is a frequent cause of consultation in hospital emergency services. In 80% of cases, it is a mild TBI which is defined as that.
ORAL ANTICOAGULANT REVERSAL STRATEGIES IN PATIENTS WITH MILD TRAUMATIC BRAIN INJURYINTRODUCTION: Traumatic brain Injury (TBI) is a frequent cause of consultation in hospital emergency services. In 80% of cases, it is a mild TBI which is defined as that.

INTRODUCTION:

Traumatic brain Injury (TBI) is a frequent cause of consultation in hospital emergency services. In 80% of cases, it is a mild TBI which is defined as that 14-15 points in the Glasgow Coma Scale (GCS). It is also estimated that in 10-20% of cases, patients are anticoagulated. The association of TBI, advanced age and anticoagulation is potentially serious.

 

OBJECTIVE:

To analyze the strategies of oral anticoagulation reversal in patients who have entered in the Observation Area of a third level hospital during a period of 3 consecutive years with diagnosis of mild TBI. Qualitative variables are represented by number of cases, percentages and quantitative variables by means of median and interquartile range.

 

RESULTS:

We included 164 patients. Among them, 97 patients had intracranial lesions. The median International Normalized Ratio  (INR) value on arrival at the emergency room was 2.42 [1.95, 3.52].

Among those patients who did not have TBI lesions, only those patients presenting supratherapeutic   (INR:> 3 ) were treated with the administration of Vitamin K intravenous.

For those patients with lesions, it were used associated with Vitamin K, doses of prothrombin complex concentrate (PCC) according to the INR, based on the recommendations of Hematology. Subsequently, the INR was checked to evaluate the correct reversal (valued as INR <1,5). We also analyzed the radiological evolution of lesions at 24 hours and the development of associated adverse events.

In addition, guidelines were established according to INR range at admission (INR 1.5-1.9, INR 1.91-3, INR 3.01-5 and INR> 5, corresponding to doses of 10, 15, 20 And 25 IU / kg respectively)

 Following this guideline, only 2 of the 65 patients who received PCC remained with INR> 1.5, requiring additional doses. There were 6 patients who received lower doses than those scheduled.

INRs> 1.5 postreversion were more frequently associated with unfavorable radiological evolution of intracranial lesions

 

CONCLUSION:

The administration of PCC at the doses described above provides a safe and effective way of reversing oral anticoagulation in anticoagulated patients with TBI


Pilar CONDE (SEVILLA, Spain), Reagie DUSSECK, Jesus MORENO, Ignacio PEREZ-TORREZ, Maria PEREZ, Alberto MORENO
08:30 - 17:40 #11612 - Orbital cellulitis complicated with meningitis and cavernous sinus thrombophlebitis in a young male.
Orbital cellulitis complicated with meningitis and cavernous sinus thrombophlebitis in a young male.

A 24 year old man presented in the emergency department with sepsis and meningitis, due to orbital cellulitis.  He had a skin lesion on the cheek, which evolved to orbital cellulitis and sepsis. Diagnosis of orbital cellulitis was confirmed by CT scan. MRI  showed cavernous sinus thrombosis, a dangerous complication of orbital cellulitis with a high mortality. Blood cultures showed MSSA, which was treated with high dose intravenous antibiotics for several weeks. This man survived, with only diplopie as a sequela.

Discussion: Orbital cellulitis is an emergency. It is important to distinguish between preseptal cellulitis and orbital cellulitis, because orbital cellulitis may cause loss of vision and even death. Complications, including orbital or brain abscesses, meningitis and cavernous sinus thrombosis, must be excluded by CT or MRI scan of the orbits and sinuses. Immediate treatment with adequate intravenous antibiotics is essential.


Fien DEWULF (jabbeke, Belgium), Stefaan REYNDERS
08:30 - 17:40 #11123 - Ossification of the posterior longitudinal ligament resulted in spinal cord compression after a minor cervical hyperextension injury.
Ossification of the posterior longitudinal ligament resulted in spinal cord compression after a minor cervical hyperextension injury.

Introduction
Ossification of the posterior longitudinal ligament (OPLL) is characterized by the development of cortical bone made up of lamellar bone with developed Haversion canals with or without marrow fat. The ossification is located along the posterior margin of the vertebral body, in the posterior longitudinal ligament, and is most commonly found in the mid-cervical spine (C3-C5).
OPLL is one of the most common causes of myelopathy in Asians. The disease has a prevalence of 1.9% to 4.3% in Japan and 0.01% to 1.7% in the United States and Europe. It is most commonly diagnosed between the fifth and seventh decades of life, most frequently between the ages of 50 and 60 years. Prevalence in males is twice that in females.
Reported here is a case of OPLL resulting in spinal cord compression after a minor cervical hyperextension injury.

Case report
A 66-year-old male presented with weakness of 4 limbs after traffic accident 20 minutes prior to admission. Minor cervical hyperextension was told by the patient in the traffic accident. Initial vital signs were temperature 36.9℃, pulse rate 77/min, respiratory rate 20/min, blood pressure 118/86 mmHg, room air SpO2 100%. Physical examination revealed quadriplegia ( muscle power of 4 limbs: all grade 1). The sensory of 4 imbs were preserved.
Cervical spinal CT without contrast was arranged and the result revealed OPLL of C2,3,4 with severe anterior indentation on the thecal sac and spinal cord. Neurosurgeon was consulted and operation with corpectomy was suggested.

Discussion
The exact pathogenesis and natural history of OPLL remain unclear, there is no standard treatment for patients with asymptomatic OPLL, and there is disagreement about the best surgical approach for surgery.
Older patients with symptoms of myelopathy after trauma should undergo early CT or MRI study looking for cord compression due to stenosis, spondyloarthrosis, and/or OPLL. This case highlights the devastating consequences of even a mild hyperextension injury in a patient harboring extremely severe but previously undiagnosed OPLL.


Jiun-Jia CHEN (Taichung City, Taiwan)
08:30 - 17:40 #11554 - Out-of-hospital cardio-respiratory arrest management.
Out-of-hospital cardio-respiratory arrest management.

Background: Out of hospital cardio respiratory arrest (CRA) frequently leads to emergency calls. The decision to resuscitate a CRA outside of hospital depends on many factors (age, underlying pathology, intervention delay). The aim of this study was to detemine the epidemiology of CRA outside of the hospital and to evaluate their management by SMUR teams; in particular the decision to resuscitate or not.

Methods: a retrospective, descriptive study over a period of 12 months. Epidemiological, delays of intervention, pre hospital management and outcome were collected.

Results: Inclusion of 114 intervention for CRA (67 man and 47 women). The mean age was 63± 13 years. A history of diabetes and hypertension were found in 33% and 23% of cases, followed by coronary artery diseases (18.5%). The mean departure time of SMUR team was 6±4 minutes. The estimated average duration of No Flow was 22 minutes. The resuscitation decision was taken by the SMUR team for 53 victims (46.5%). For other patients, the decision not to resusitate was motivated solely by the finding of a confirmed state of death in an elderly patient (p=0.045). The predictive decision factor for resuscitation was the No Flow time (P<0.001). Resuscitation of cardiac activity was obtained in 11 patients (21%), 9 of whom were transferred to emergency services when they died within 48 hors.

Conclusion: The decision to resuscitate a CRA outside of the hospital depends more on the No Flow time and the patient's age than on the presumed etiologies.


Saida ZELFANI, Wided BAHRIA (tunisie, Tunisia), Syrine KESKES, Hela MANAI, Sana DRIDI, Chedly GHANEM, Mounir DAGHFOUS
08:30 - 17:40 #11747 - Overcrowed Emergency Departments. The Impact of Advanced Nurse Practitoners.
Overcrowed Emergency Departments. The Impact of Advanced Nurse Practitoners.

Overcrowding and long waiting times often delay emergent care. It adds to anxiety and frustration and often results in poor clinician-patient relationships. The role of the Advanced nurse Practitioner (ANP) in the Emergency department (ED) has developed as a result of a transformation of health services in the Republic of Ireland (ROI) since the 1990's. The introduction of the advanced practice role was part of a strategic development to help to reduce overcrowding, patient waiting times and improve patient experiences (Thompson and Meskell, 2012).

The aim of this study was to analyse the impact of ANP's in the delivery of optimal standardised assessment in minor injuries, the service expected by patients and on waiting times. Portiuncula ED registers over 26500 patients annually, 10% of these are seen by ANP's. A retrospective audit of this cohort of patients was carried out by recording registration times, triage time, time of initial assessment by ANP and discharge time on an Excel spreadsheet over the 2016 year. The results showed that patients waited an average of 24 minutes before being seen by the ANP and an average length of time from assessment to discharge was 50mins. 77% of patients were treated completely by the ANP's. The 23% that were referred required specialist intervention namely Orthopaedic and Plastics surgery. These had increased the length of waiting times (90mins), which was reflected in increased times in awaiting decision making by specialist and awaiting transfer to other hospital times.

The results show that ANP's continue to have a positive impact on the waiting times of patients attending the ED. Other audits throughout Ireland have demonstrated that ANP's reduced the waiting times by up to 20% (Griffin & McDevitt, 2016). The Emergency Medicine Programme KPI's (2013) recommend a standard 6 hour waiting time for patients attending an ED and fewer than 5% should leave before completion of treatment. The ANP intervention in this streamlined cohort of minor injuries in Ireland has resulted in shorter waiting times and has had a positive impact on patient satisfaction and reduces overcrowding.


Aidan FALLON (Galway, Ireland), Kiren GOVENDER, Enda JENNINGS
08:30 - 17:40 #9897 - Pain The Most Common Symptom In The Emergency Department: An Observational Study.
Pain The Most Common Symptom In The Emergency Department: An Observational Study.

The objective of this observational study was to evaluate the most common symptoms that appear in the emergency department, with focus in pain symptom, which require adequate educational preparation and knowledge to deliver safe and quality patient care. The study was conducted in the emergency department of the Vlora Regional Hospital, Albania during March and June 2016. A standard questionnaire based on the literature was used to assess symptoms of the patient. The administration was made by nursing students while performing their teaching practice in hospital. The numeric 0–10 scale was used for the evaluation of symptoms (0=not at all; 5=moderate; 10=worst possible). A total of 45 patients were the study sample. They were excluded patients in critical condition and those who could not respond to answers. An oral consent was given by each patient after they were informed. Average age of patients was (55.11 ± 17.7) years. Pain: cut point 6 for the 26.26% (n=12) of patients, while cut point 7 and 8 of pain reported by the same percentage 15.56% (n=7). Head and chest pain, the most common clinical presentation, respectively (46.67%) and (40%). Most frequent diagnoses High blood pressure and Vertiginous syndrome. A coordinated care intervention with the primary care to reduce emergency department presentations among chronically ill patients, and knowledge of the most common symptoms of patients by staff nurses, with focus in the management of pain, operating in the emergency care are essential for the improvement of patient health outcomes.


Fatjona KAMBERI (Vlore, Albania), Enkeleda SINAJ, Vjollca NDREU
08:30 - 17:40 #11805 - Painless aortic dissection presenting with vertigo as the chief complaint.
Painless aortic dissection presenting with vertigo as the chief complaint.

Objective: Aortic dissection is a condition that can be fatal if undiagnosed. with aortic dissection is defined as separation of layers along the long axis of the intima-media layer of the aorta associated with high mortality and morbidity.It is the actual cardiovascular emergency that requires prompt diagnosis and treatment. Classically patient has a tearing pain in chest, back and abdomen. However, %5-15 of cases presents painless aortic dissection. We aimed to explain a case who brought to emergency department with a vertigo attack like condition. 

Case:63-year -old patient was presented to our emergency deaprtment. 

His major complaint was dizziness. His was pale and he had cold sweats. He had no history of benign positional vertigo and he did not use any medications. He had a vertigo attack started half an hour ago and he could not walk and he had lied supine and called ambulance. His blood pressure was 82/61 mm/Hg, his heart rate was 93/min, respiratory rate was 19/min, his blood sugar level was 131mm/Hg. His neurologic examination was unremarkable; there was not any dysmetria or dysdiadochokinesia and four extremity did not have any weakness. His rectal examination was normal. However his left radial pulse could not be took.His electrocardiogram was in sinus rhtym. Bedside ultrasonography performed and aortic dissection shown in abdominal ultrasonography. A thorocaabdominal computerized tomography(CT) was taken to confirm dissection. In CT Standford Type C aort dissection was detected. Patient had consulted to cardiovascular surgery team. Patient had operated and post-operative tenth day he discharged with no morbidty. 

Discussion:Aortic dissection classically presents with tearing chest and back pain but however it can be presented painless with any symptoms. This patients can be presented with atypical neurological findings such as syncope, hemiparesis, hemiplegia or complaints such as myocardial infarction, dysphagia and side pain can also be applied to emergency services. In our case, patient admitted to hospital with an atypical dizziness complaint. We explain a case radial artery pulselessness witch revealed in detailed physical examination and dissection detected on CT. Dizziness or vertigo are usually benign symptoms but we should make detailed physical examination. 


Sinan KARACABEY, Arda KOCATAŞ (istanbul, Turkey), Erkman SANRI
08:30 - 17:40 #11017 - Palliative care and pre-hospital emergencies : the need for a dedicated file?
Palliative care and pre-hospital emergencies : the need for a dedicated file?

Introduction: In a prehospital situation, in the presence of a palliative care patient (PP), the legal aspect requires of the emergency doctor the collection of specific information needed to confirm the palliative care and to decide on the fate of the patient. The aim of the study was to assess the quality of the collection of this data in patients for whom a decision of withdrawal in life-sustaining treatment (WLST) has been taken by a pre-hospital medical team.

 

Material and method: retrospective study of practice. Accordance of an Ethics Committee. Included: 1. The PP for which the rating "End of Life" or "palliative care" was found in the pre-hospital medical record; 2. the PP not having benefited from a resuscitation during a vital sign failure. The variables sought in the file: age, sex, dependence assessment, arguments in favor of active resuscitative measures, opinion of the patient, the person of trust, of the family, existence of an advance directive, a community decision.

 

Results: from 11/01/2014 to 07/31/2016, 88/2888 patients have been included. If we consider the 100% patients (n=88), median age were 88 years IQR [80.5 -92] with 60.2% women. The notification rate of key information in the prehospital report form are following:  vital signs of acute failure 100% (n=88), main chronic pathology (neoplasia, neuro degenerative diseases, others) 100% (n=88); functional autonomy with: Iso Resource Group 25% (n=22), communication 43% (n=38), movement 50% (n=44), state of skin 10% (n=9), grooming 17% (n=15), food 15% (n=13), incontinence 7% (n=6); opinion of the patient or advance directive or opinion of person of trust/family 88% (n=77); argument in favor of active resuscitative care 49% (n=43); community decision with at least to physicians 39% (n=34) with their identification  (name, function: 100% for 1 physician, 3% for the second physician). 

 

Discussion: The constraints of pre-hospital emergency complicate decisions of resuscitative care. The sensitive data are too often missing. A report form for prehospital active resuscitative care is in a process of evaluation, with the help of medical doctors in palliative care. The lack of training for emergency professionals in palliative care may explain the difficulties encountered in the face of resuscitative care. The training of emergency physicians in palliative care needs to be strengthened.


Jonathan GONZVA, Isabelle KLEIN (PARIS), Jimmy ROBERT, Thibault LECORFEC, Daniel JOST, Carole RASO, Xavier LESAFFRE, Nicolas GENOTELLE, Jean Pierre TOURTIER
08:30 - 17:40 #11297 - PALPITATIONS IN PATIENT WITH RHEUMATOID ARTHRITIS.
PALPITATIONS IN PATIENT WITH RHEUMATOID ARTHRITIS.

A 57 years old woman presented in the emergency room with palpitations in the last week accompanied of dizziness and oppressive chest pain 5 minutes duration each episode. As a medical history presented a left tonsil carcinoma in follow-up by ORL,  disease free, and rheumatoid arthritis since 2010 currently in treatment with leflunomide since 2011 with full response, RF+; no symptom since 2 years. She was born in Philippines and lives in Spain since 19 years ago.

In the first EKG in the Primary Healthcare presented an atrial fibrillation with 120 bpm of heart rate so that iniciate amiodarone perfusion and arrived to the hospital with sinus rhythm to 80 bpm and low voltages with flattened T wave in all derivations. In the chest X-ray objective important increased cardiac index no presented in previous X-ray. No alterations in blood test, and the high-sensitive troponin-I is normal.

With the suspicious of pericardial effusion is discussed with cardiologist to make an echocardiography: severe pericardial effusion with incipient signs of hemodinamyc compromise without associated cardiac tamponade.

 A thoracic CT is performed: Severe pericardial effusion up to 46 cm thick.

During her admission to the emergency room the patient has an episode of atrial fibrillation with ventricular frequency 170-180 bpm well tolerated hemodynamically. Amiodarone intravenous is prescribed persisting atrial fibrillation so that is necessary electric cardioversion under sedation with propofol. This is effective and the patient entry in sinus rhythm.

 With diagnosis of pericardial effusion as a rheumatoid arthritis versus oncological complication she was admitted in Intern Medical Unit and a pericardiocentesis is performed 2 days later getting 800ml of hematic pericardial fluid. In the analysis of pericardial fluid is found glucose 68mg/dl, protein 69.0 g/L, LDH 2.039 U/L, hematies 1.920.000/microL, 2.970/microL leukocytes with 61% neutrophils. No cells in fluid. This is compatible fluid with rheumatoid arthritis complication ruling out oncological cause.

She was discharged with no other cardiac event nor pericardial effusion.

Rheumatoid arthritis is a chronic autoimmune inflammatory disease occasionally associated with severe extra-articular manifestations, mostly in cases of longstanding highly active disease. However pericarditis and pericardial effusion are less frequent, only 2-3%, especially in absence of concomitant articular activity. Major disability, smoking and RF+ are strong predictors of further development of severe extra-articular manifestations. Our patient didn’t have active disease since 2 years and the only risk factor of cardiac manifestations is RF+, restarting the disease activity with a rare extra-articular manifestation


Carmen RODRIGUEZ (PALMA DE MALLORCA, Spain), Karina VALDEZ, Leticia BREGANTE, Maria GRANDE, German FERMIN, Claudina REVOL, Julio OLSEN, Esperanza RIUTORT, Bernardino COMAS
08:30 - 17:40 #10126 - Pancreatitis secondary to hyperlipidemia.
Pancreatitis secondary to hyperlipidemia.

We present a case of a 24-year-old Romanian female presenting to a UK Emergency Department with a 5-month history of abdominal pain.  She had previously presented to the same Emergency Department 5 months earlier with similar symptoms.  On that occasion, she had been diagnosed with pancreatitis and admitted to the care of the Surgical team.  She had failed to attend a follow-up outpatient appointment and had been discharged back to the General Practitioner (GP). 

 

She re-presented to the Emergency Department on Christmas Eve with similar symptoms.  There was a difficulty in the consultation due to a language barrier between the clinician and the patient.  Therefore, a telephone interpreting service was used.  This added detail to the history, the patient was unaware of her previous diagnosis of pancreatitis, as well as explaining that she had not understood the letters sent from the hospital.  Examination was unremarkable apart from mild epigastric tenderness on a soft abdomen.  Pregnancy test was negative and urinalysis was unremarkable.

 

Laboratory tests in the form of Full Blood Count, Urea & Electrolytes, Liver Function Tests, Amylase and C-reactive Protein were send.  The Emergency Department was alerted to the abnormal profile of the blood by a laboratory technician calling to explain that the biochemistry sample was grossly lipaemic.  The sample being described as having "a similar consistency to clotted cream".  Because of this only a limited profile of results was available.  These results showed the Amylase to be elevated to six times greater than the reference range, Triglycerides and cholesterol results were elevated to 20 times greater than the reference range.  A diagnosis of pancreatitis secondary to hyperlipidaemia was made.

 

The surgical team were consulted and given the chronic nature of the pancreatitis the patient was referred to the fast-track pancreatic diseases outpatient clinic.  Correspondence was sent to the patient's General Practitioner regarding investigation and treatment of the hyperlipidaemia.  Information about the diagnosis and management was communicated to the patient using the telephone interpreting service.  The patient was subsequently commenced on a high dose statin and investigated for familial hyperlipidaemia.

 

This case is interesting as it highlights a number of important issues.  Pancreatitis can be associated with hyperlipidaemia both as a cause and as a consequence.  High levels of triglycerides can precipitate cases of pancreatitis, conversely, hyperlipidaemia can be observed because of pancreatic necrosis.  Hyperlipidaemia should be considered as a potential cause of pancreatitis, in particular, where no other precipitating factor can be found as it is a controllable factor which has impact on other diseases such as cardiovascular disease.  Indeed, in this case the hyperlipidaemia as a cause of the pancreatitis had been missed at the time of her initial presentation.

 


Dr Jonathan HOLMAN (Cardiff, ), Mayada ELSHEIKH, Stephen BUSH
08:30 - 17:40 #10847 - Paraplegia in 24 hours.
Paraplegia in 24 hours.

CASE REPORT :

Reason for consultation :

Left lower limb paresthesia

Personal history :

Hemophilia A
Vitiligo
Nephritic colic
VHC

No usual treatment



Current illness :

A 38-year-old male patient is referred to the HUSE emergency department based on SUAP. Patient initially reports hypoesthesias in the lower left limb from Thursday to noon, when he went to the MAP and was diagnosed with lumbociatalgia, requesting a review the next day. As the neurological clinical condition worsened, it was referred to H Inca where, after being assessed and examined, the patient is discharged home.

The patient refers to a progressive neurological clinical picture that begins in the form of paresthesias in the lower left limb that ascends to ipsilateral hemipelvis associated with absolute loss of mobility, reports that he came to H Inca wandering but after 18h could not stand, Needing a wheelchair to leave the hospital

Physical exploration :

Patient bedded, conscious and oriented. Collaborator. Controlled pain
Left lower limb with absence of patellar reflex and achileo, distal 0/5 force, no plantar or dorsal flexion, inability flexion of hips with force 1/5, absolute anesthesia to anterior aspect of left thigh

Right lower limb: 4/5 proximal and distal force, refers to posteromedial dysesthesias, present ROT.
Anesthesia in the perineum to the back of the penis
Bladder balloon palpation, no priapism, no sphincter incontinence




Complementary explorations :

Lumbar columan rx, without clear acute osseous lesion

MRI column without contrast of the fusiform Collection of 80 x 19 x 18mm in the posterior epidural space with extension in the longitudinal direction from L1 to L3, and to the left L2L3 conjunction hole, compatible with hyperacute hematoma. It occupies almost the whole of the spinal canal and displaces and compresses the roots of the horse's tail. No herniated disc is identified. Medullary cone of normal morphology and signal. There are no alterations in the lower dorsal or cervical segment.



Diagnostic orientation:

 Longitudinal epidural hematoma L1 to L3 with spinal compression and horsetail



Procedures:

Preoperative diagnosis: Epidural compressive hematoma D12 / L1 / L2 / L3

Surgical intervention: D12 to L3 decompressive laminectomy + hematoma evacuation + posterolateral arthrodesis instrumented with the Firebird D12 / L1 / L2 / L3 system


Clinical evolution:

Favorable evolution in the postoperative period. No intraoperative incidences. It has progressively improved the motor and sensory function of LLL. At the time of discharge, recovery in lower limb D with force 5/5. In the lower left limb it has a proximal motor deficit 4/5 and 3/5 distal with sensory alterations and paresthesias.

During his hospital admission he has received attention and valuation from the Traumatology, Hematology (Hemophilia A), Digestive, Rehabilitation and Physiotherapist, Urology, Internal Medicine and Neurology departments.

At the time of adequate discharge of pain, he has begun progressive ambulatory with assistance


German Jose FERMIN GAMERO, Julio OLSEN, Lara PUERTO, Pedro RULL BERTRAN, Bernardino COMAS DIAZ, Elena ALFARO GARCIA-BELENGUER, Enara BELANDIA DE BUSTURIA (PALMA DE MALLORCA - ISLAS BALEARES, Spain)
08:30 - 17:40 #11453 - Paroxysmal supraventricular tachycardia in newly diagnosed adult tuberous sclerosis complex and cardiac rhabdomyoma: report of one case.
Paroxysmal supraventricular tachycardia in newly diagnosed adult tuberous sclerosis complex and cardiac rhabdomyoma: report of one case.

Introduction: Tuberous sclerosis complex (TSC) is a genetic neurocutaneous disorder that is characterized by multiple organs involvement. It is an autosomal dominant genetic disorder with an incidence of approximately 1 in 5000 to 10,000 live births. Cardiac rhabdomyoma, which has been known to be related with tuberous sclerosis complex, occasionally cause supraventricular tachycardia and was rarely reported in adult case. We reported a newly diagnosed case with typical findings of TSC and complex with supraventricular tachycardia in ED.

Case report: Our patient, a 74 y/o woman with comorbidity of CKD, presented to our ED because of vomiting, diarrhea and intermittent palpitation since the midnight on ED visiting day. Physical examination showed facial angiofibromas and periungual fibromas involved toenails. Initial vital signs showed pulse rate 71bpm, BP 117/68mmHg, BT 36.3^C. Initial ECG showed normal sinus rhythm. CXR revealed bilateral diffused lung infiltration. Lab test showed WBC 6270/ul, Hb 10.3g/dl, Cre 3.78mg/dl, TnI>0.01ng/ml. However, palpitation developed in ED later on. ECG showed PSVT and was subsequently corrected by adenosine(6mg IVB). Heart echo showed punctate echogenic focus over left ventricular region. Computed tomography was done and showed subependymal tubers of bilateral ventricles, myocardial focal fatty deposits(suspected cardiac rhabdomyoma), massive angiomyolipomas of bilateral kidneys and lymphangioleiomyomatosis(LAM) of bilateral lungs.. Tuberous sclerosis with multiple organ involvement and suspected cardiac rhabdomyoma were impressed in ED. Patient was admitted to hospital. Hydration and symptomatic treatment were given and she was subsequently discharged few days later.

Discussion: Cardiac arrhythmia is a significant problem in TSC. The mechanisms of arrhythmia have often been resulted by the formation of specific cardiac rhabdomyomas. The effects of the arrhythmias were extremely variable. The treatment strategies for any arrhythmia are not affected by the presence of TSC. Observation, antiarrhythmic medications, catheter and surgical ablation, implanted pacemakers and defribrillators remain beneficial for treatment as they do in general individuals. 


Kian Ching ER (Chiayi, Taiwan), Ya Chin LIANG
08:30 - 17:40 #11895 - Particularity of type2 diabetic ketoacidosis patients in emergency department.
Particularity of type2 diabetic ketoacidosis patients in emergency department.

Background:

Diabetic ketoacidosis (DKA) is a serious and life-threatening complication of diabetes mellitus. While the conventional belief is that DKA is an uncommon presentation of type 2 diabetes, recent studies report an increasing rate of DKA associated with this category of diabetes and a new entity of ketosis-prone type 2 was recently described.

According to recommendations, the treatment of patients who present with DKA is fairly standardized and does not differ according to their  phenotype.

 

Purpose:

The aim of this study was to compare the initial demographic characteristics and prognosis between the two categories known as type 1 diabetes mellitus and type 2 diabetes mellitus in DKA patients.

 

Methods:

Prospective study over 2-year period conducted in patients with moderate to severe DKA patients hospitalized in emergency department (ED). Standardization of DKA management occurring to ADA recommendations: fluid replacement, insulin therapy and potassium supplementation. Fischer exact test and T-test were used when appropriate to compare the type 2 diabetes group.

Results:

Out of one-hundred and six patients (sex-ratio=0.63; mean age 36 ± 16 years) who were hospitalized for DKA in ED during the study period, thirty-one (33.7%) were classified as type 2 diabetes and sixty-one (66.3%) as type 1 diabetes. Type 2 patients were older (mean age: 53 vs 27; p=0.000). Comorbidites were more frequent in the type 2 group: hypertension (p=0.000), dyslipidemia (p=0.002), coronary disease (p=0.05) and kidney failure (p= 0.32). There were no differences between the two groups in initial biochemical data: pH (7.11 vs 7.14 ), serum bicarbonate ( 6.9 vs 7.6 mmol/l), anion gap (29 vs 30 mmol/l ), blood glucose levels (37 vs 32 mmol/l) except the renal function with significantly higher rate of acute functional kidney failure in type 2 group.

Outcomes data: time recovery (14 vs 11 hours; p=0.07), insulin dose to recovery (70 vs 53 Units; p=0.02), Length of stay in Intensive Care Unit (32 vs 27 hours; p=0.27), length of total hospitalization (46 vs 34 hours; p=0.04).

 

Discussion:

DKA patients with type 2 diabetes are characterized by higher rate of acute functional kidney failure in the initial presentation and higher insulin requirement dose to recovery explaining longer hospital stay. The peripheral insulin resistance characterizing the type 2 patients and the failure of contre-regulation mechanisms due to the advanced age can explain these findings.

 


Sarra JOUINI, Fatma HEBAIEB (Ariana, Tunisia), Hana HEDHLI, Rym HAMED, Asma ALOUI, Dorra CHTOUROU, Mohamed MEZGHANNI, Chokri HAMOUDA
08:30 - 17:40 #10971 - Patient house calls in Attica and Thessaloniki, Greece (2005-2015): a model for emergency multi-specialty out-of-hospital medicine.
Patient house calls in Attica and Thessaloniki, Greece (2005-2015): a model for emergency multi-specialty out-of-hospital medicine.

The SOS-doctors are a network of physicians who perform house-call visits in the areas of Attica and Thessaloniki, Greece. Patients requesting medical services by the SOS doctors during the period 1/1/2005 – 31/12/2015 were eligible for inclusion in this retrospective analysis. During this period 335, 212 home visits were performed. Females used this service more frequently compared to males (60.5% versus 39.5%). Among the age-groups, patients aged over 75 years made 56.6% of all house calls. Less phone requests were recorded during autumn than in winter (21.1% versus 29.1%). Infections were the most common cause of house-visits (29%). Cardiovascular diseases were also a significant proportion (10.3%), followed by musculoskeletal (9.1%), gastrointestinal (6.3%) and neurological disorders (3.7%). An increasing demand for radiology at home was observed, starting at 352 calls in 2009 and reaching 2,230 in 2015. Finally, 9.2% of patients were advised to be admitted into a hospital. A shift towards older age, but not the oldest old (>90 years), and acute conditions was observed. The study confirms that home visits retain a significant role in the modern health care systems.


George THEOCHARIS, Spiridon BARBAS (ATHENS, Greece), Theodore SPIROPOULOS, Petroula STAMOULI, Matthew FALAGAS
08:30 - 17:40 #11976 - Patient with breast trauma who presented with dizziness: case report.
Patient with breast trauma who presented with dizziness: case report.

Background: Breast hematoma is the result of breast parenchyma infiltration by the extravasated blood. Blood is usually collected in a focal focus. It can usually occur after trauma, surgical intervention and biopsy. Bleeding tendency is higher in the people with bleeding diathesis. While small-sized hematomas frequently resorb spontaneously, larger hematomas can lead to inflammation and fibrosis. Therefore, clinical follow-up is adequate for small hematomas while drainage is indicated for large hematomas.  The arterial blood supply of breast is derived from axillary artery branches. Isolated traumas of breast is quite rare.

Case: A 66-year-old female patient was admitted to emergency service with the complaints of black-out of vision, dizziness, pain in the left breast. On the day of admission, two hours before admission, her foot stumbled on the carpet and she hit her left breast to the edge of furniture while falling down. A few hours after this, dizziness and black-out of vision occurred in the patient. She also complained of pain and bruising of breast. The patient who was on anti-aggregant therapy for atrial fibrillation had no other systemic disease or drug history. The patient was hypotensive (84/48 mmHg) at the time of admission to emergency service. Other vital findings were normal. On physical examination the patient was pale and sweating. There was approximately 18 x 9 cm of ecchymotic area in the left breast and its size increased compared to the right breast (figure). The hemoglobin level was measured as 10.8 g / dl in the whole blood count of the patient and the hemoglobin value was 9.3 g / dl in the control blood count which was studied one hour later. Other laboratory findings were normal. Except for the hematoma in the breast, the patient had no evidence of bleeding or other examination finding. There was no rib fracture on the direct chest graph. On the thoracic CT scan, two hematoma areas measuring 136x86 mm and 84x57 mm in size were observed in the left breast. The patient was consulted to the general surgery clinic. The patient, who did not accept the recommendation of being hospitalized, left the emergency service.

Conclusion: Breast trauma is not common in emergency service. The patients who have trauma to this area do not consider it as emergency. However, even with isolated breast trauma, especially under aggregant treatment (as in our patient, it can cause severe bleeding, which can cause significant drop in hemoglobin and blood pressure. Emergency physicians should be careful about the trauma of this area. 


Zeynep CAKIR (ISTANBUL, Turkey), Ilker AKBAS, Abdullah Osman KOCAK, Nazim Onur CAN, Atif BAYRAMOGLU
08:30 - 17:40 #10676 - Patient with severe abdominal pain with hemodynamic instability secondary to acute intestinal ischemia.
Patient with severe abdominal pain with hemodynamic instability secondary to acute intestinal ischemia.

MEDICAL HISTORY:

Patient with 50 years old and with a medical history of hypertension, smoking 1 pack a day and chronic alcoholism (several glasses of whiskey and several daily beers) atended in emergency room with abdominal pain of 48 hours of evolution accompanied by vomiting of food look and diarrhea ( 5-6 stools per day), last stools mixed with blood as reported by the patient. He denies fever or other associated clinical.

The patient was admitted to the observation area due to poor general condition and hemodynamic instability and presented 2 episodes of vomiting with bloody content plentiful so nasogastric tube is placed. General Surgery is informed telephonically after additional testing and the patient is transferred to the reference hospital for abdominal CT and assessment by a specialist.

EXPLORATION

BP: 110/85 mmHg; FC: 150 bpm , baseline oxygen saturation 92%. Afebrile

Regular condition, well hydrated and perfused. Sweaty.

Cardio-respiratory auscultation average.

Abdomen: Soft and relaxed with palapcion pain in left lower quadrant abdominal defense associated with decreased bowel sounds in this nivel. Remaining unchanged.

Complementary tests:

Analytical blood with coagulopathy. Biochemistry with Urea 63, Creatinine: 2.17. Normal blood counts.

Rx: abdominal distension of small bowel loops.

Abdominal CT: gas seen in radical portals, superior mesenteric veins, dilatation of small bowel loops and discrete amount of perihepatic, perisplenic and Right Iliac Fossa liquid. Findings consistent with acute intestinal ischemia.

Clinical Trial: Acute intestinal ischemia

Evolution and Treatment:

After performing abdominal CT and valuation General Surgery, emergency surgery is decided

Surgery with significant generalized dilatation of the small intestine with signs of vascular congestion and intestinal turbid liquid. Two areas of vascular compromise ileum level, one at 60 cm from ileocecal valve and one 10 cm. Resection of affected bowel ileum segments of approximately 70 cm is performed. During surgery, the patient needs a lot of hemodynamic instability of fluid transfusion also 1000cc crystalloid and plasma. Antibiotic prophylaxis is performed.

The patient was admitted to ICU postoperatively with norepinephrine infusion of high-dose instability.


Jose Ignacio VALERO ROLDAN, Rafael INFANTES RAMOS (Málaga, Spain), Carolina GARRIDO CANNING, Cristina FERNANDEZ- FIGARES MONTES, Maria Eugenia REYES GARCIA, Ivan VILLAR MENA
08:30 - 17:40 #11163 - Patterns of involuntary acute poisoning in pediatric patients: a single-center study.
Patterns of involuntary acute poisoning in pediatric patients: a single-center study.

BACKGROUND:

Poisoning among children is a current issue in pediatrics. The pattern and risk factors of poisoning are heterogeneous and vary within the same country.

OBJECTIVE:

The aim of this study was to describe demographic features, the nature of poisoning and the outcome of patients poisoned in order to identify children at higher risk.

MATERIAL AND METHODS:

A retrospective study of the pediatric emergency care unit database was performed. The study group consisted of 584 patients with age under 18 years, who were admitted to the emergency care unit of the Emergency Hospital for Children "St Mary" in Iasi, Romania, due to acute poisoning suspicion or diagnosis, between the 1st of January 2016 and the 31st of December 2016.

RESULTS:

In the group of 584 patients admitted in the emergency care unit, 162 were involuntary poisonings. The average age was 5 years old (between 0 months old and 11 years old0), with a sex distribution approximatively equal (boys to girls= 1:1.025).

There were no statistic differences between the urban and rural provenience of the patients (rural to urban= 1:1,16).

Toxic substances to which children were exposed were various: improperly stored drugs (tablets or syrups) in 80 cases (49,38%), sparkling substances (detergents, shampoo, soap) in 17 cases (10,49%), alcohol in 12 cases (7,4%), household chemicals (sodium hypochlorite, caustic soda) in 11 cases (6%), insecticide, rodenticides, diluent and petroleum solvents 9 cases (5,5%). Exceptionally, children ingested  foundation cream, cologne, paints, drying granules, oral contraceptives, ornamental plants or mandrake.Time between ingestion and the emergency unit admission varied from a few minutes to 12 hours. In 102 cases (62,9%) patients were admitted in the first 2 or 3 hours, before symptoms occurred, when parents took note of the incident, and in 60 cases (37,03%) patients were admitted after the specific symptoms occurred. In 10 cases the symptomatology  was severe, including coma, 2 cases requiring endotracheal intubation.The treatment consisted in supportive measures for vital functions, gastric lavage (when indicated), antidote administration (when necessary). 127 children were hospitalized, the average length of hospitalization was 5 days (between 1 day and 3 weeks). In all cases the outcome was favorable , there were no deaths.

CONCLUSIONS:

Accidental poisoning exposures from household products and drugs remains a significant problem for pediatric patients. Further education of parents, care takers and the employees responsible for child-resistant containers is needed to prevent cases of pediatric poisoning.


Carmen OLARU, Carmen OLARU (IASI, Romania), Valentin OLARU, Solange Tamara ROSU, Smaranda DIACONESCU
08:30 - 17:40 #10916 - Pediatric oncology patients' visits in the emergency department of children's hospital.
Pediatric oncology patients' visits in the emergency department of children's hospital.

BACKGROUND: Children with cancer are unique and particularly sensitive group of chronic patients, as many are undergoing an aggressive immunosuppressive treatment, so it is very important to consider with care any new symptom.

AIM: The aim of the study was to analyze the reasons of the children with cancer visiting the ED in Children´s Hospital Zagreb, Croatia.

PATIENTS AND METHODS: During 2014, out of 10.025 visits to the ED, 71 (44 M, 27 F; 7.84±5.81 yrs; 1-18 yrs) were visits of children with cancer (0.71%). Data were analyzed with descriptive statistics, and for significance of a correlation were used Spearman R and Chi-square test.

RESULTS: The majority arrived as an emergency (93%), while only 7% were sent with a notice from a pediatrician. It was probably due to their parents being more concerned than the parents of children with no malignancy.

Only 2 children were in remission and 69 had an active disease and undergoing an immunosuppressive treatment. Main symptoms were fever (68%) and gastrointestinal problems (13%); other symptoms were not as common. Only 10 were released home, while 61 (86%) were hospitalized. High number of hospitalized patients was due to their underlying condition and was a measure of caution, not necessary the expression of the severity of their ED visit illness. We also searched for relation between the age and the decision whether she/he could be released home, but no significant correlations were found (Spearman R= -0.177), so the age was obviously not a decisive factor for hospitalization.

Among all, 52% of the patients suffered from a fever with neutropenia and 15% had fever with no neutropenia. In remaining 32% the diagnosis was mostly secondary anemia and thrombocytopenia (4 cases), secondary thrombocytopenia (4 cases), vomitus (3), sepsis (3), convulsions (3), infections of the respiratory (4) and urinary (3) tract and other conditions, like insect bite, allergy to platelets transfusion and polyradiculopathy. Even though there were some differences in percentages of the children with febrile condition between boys and girls (11% boys; 22% girls), those differences were not significant (Chi-square p=0.219).

CONCLUSION: There are not many published articles on this topic and that makes this overview important. In our experience, which correlates with accessible literature, fever is the most common reason for ED visits among pediatric oncology patients and febrile neutropenia is the main cause of their hospital admission. Although there is always the same emergency approach to a severe sick child with chronic illness, emergency pediatrician must be aware of any additional symptom in this especially vulnerable group of pediatric patients and consider it with care.


Zdenka PLESA PREMILOVAC (Zagreb, Croatia), Mirta LAMOT, Alen SVIGIR
08:30 - 17:40 #11310 - Pediatric out-of-hospital cardiac arrest: the experience of a tertiary pediatric hospital.
Pediatric out-of-hospital cardiac arrest: the experience of a tertiary pediatric hospital.

BACKGROUND:

There is limited evidence concerning the incidence and final outcome of pediatric cardiac arrest in the prehospital setting. Due to the fact that central nervous system is most susceptible to the lack of oxygen and multiple organ failure is imminent, immediate response and initiation of cardiopulmonary resuscitation are of vital importance in order to maintain effective cerebral and tissue perfusion. Therefore, efforts should be directed toward the mitigation of cerebral damage and multiple organ failure due to the lack of adequate oxygen delivery. Location, age, etiology and initiation of cardiopulmonary resuscitation are key factors to survival to hospital discharge as well as to the neurological outcome (minor or severe neurological disability) amongst survivors. However, cardiopulmonary arrest in children in the prehospital setting is not reported as frequently compared to adults. Thus, first responders are not adequately trained and less familiar with pediatric assessment and resuscitation.

 

METHOD:

Children with out-of-hospital arrest that arrived in the Emergency Department in our hospital over a five year period, from January 2012 to March 2017, were included in this study. In most cases the cause that led to arrest was unknown, while in some cases the cause was one of the following: respiratory failure, trauma, drowning, sepsis, congenital heart disease, dysrythmia, sudden infant death syndrome and status epilepticus. Age, gender, early intervention by emergency medical team, survival and neurological outcome were reviewed.

 

RESULTS:

47 children aged 10 days to 14,5 years were admitted to the Emergency Department in our hospital from January 2012 to March 2017 due to cardiac arrest. The mean age of these patients was 1,76 years. 31 (66%) were male and 16 female (34%). 7 (14,9%) of these 47 children were transferred to the Emergency Department by their parents, while in the remaining 40 (85,1%) cases emergency medical team had arrived on location of arrest and had performed cardiopulmonary resuscitation.  Out of these 47 patients only 1 (2,1%) survived to hospital discharge. The infant was discharged with a tracheostomy after a prolonged period of intubation in the Pediatric Intensive Care Unit, followed by a long period of hospitalization and rehabilitation in the pediatric ward. As far as the neulological outcome is concerned, there was significant neurological disability (permanent vegetative state) on discharge.

 

CONCLUSION:

Early recognition of cardiopulmonary arrest and rapid response are key determinants to survival as well as to the final neurological outcome in out-of-hospital cardiac arrest in children. Therefore, first responders and emergency medical teams should receive continuous training in pediatric assessment and application of goal-directed pediatric life support and resuscitation guidelines. Further studies concerning the incidence of pediatric out-of-hospital cardiac arrest need do be performed. 


Konstantina MITROPOULOU (Zografou, Athens, Greece), Alexia PAPATHEODOROPOULOU, Aristoula PATSOURA, John PAPADATOS
08:30 - 17:40 #11944 - Penetrating atherosclerotic ulcer of the thoracic aorta: case report.
Penetrating atherosclerotic ulcer of the thoracic aorta: case report.

Penetrating atherosclerotic ulcer (PAU) of the thoracic aorta is part of acute aortic syndrome, so care must be taken concerning its diagnosis and treatment.

A 79-year-old hypertensive man presented with 1 h of sudden-onset severe tearing chest pain radiating to the interscapular region. On physical examination, his heart rate was 75 beats/min and regular, BP was 220/100 mm Hg bilaterally, and carotid and peripheral pulses were normal bilaterally. The lung fields were clear, and heart sounds were normal. The mediastinum was slightly widened on chest radiograph. . Initial EKG showed a sinusal rhythm with anterior negative T waves. An acute coronary syndrome was mentioned, but an acute coronary syndrome couldn’t be eliminated. Therefore, the patient received the Nicardipine to control a systolic tension (less than 120 mmHg), and EKG monitoring. The Patient was subsequently planned for Computed Tomographic angiography, which showed normal coronary arteries but Penetrating atherosclerotic ulcer of the abdominal aorta. Endovascular repair with stent-grafting was urgently performed. He improved clinically and remained well on discharge.

Penetrating atherosclerotic ulcer was first described in 1934 as a distinct pathological process. It is caused by an atheromatous plaque that becomes ulcerated and disrupts the internal elastic lamina with associated haematoma within the media of the aortic wall. An intramural haematoma forms as the exposed media is subjected to pulsatile arterial flow. Penetrating atherosclerotic ulcer has been considered as a type of aortic dissection without an intimal flap. They can present as intimal plaque ulcerations, or medial haematoma, an adventitial false aneurysm or transmural rupture. Penetrating atherosclerotic ulcer often affects the elderly, with atherosclerosis and hypertension. It typically involves the descending thoracic aorta. Although rare, the aortic arch has been reported as a site for a PAU.

This case demonstrated that PAU, although rare and often under-recognised, is potentially life-threatening and should be considered in the evaluation of chest pain. Multi-modality imaging techniques can aid the diagnosis and guide appropriate and timely management.


Zied GUERMAZI (Trévenans), Zied IBN EL HADJ, Marouene BOUKHRIS, Sami KASBEOUI, Lobna LAAROUSSI, Sonia MARRAKCHI, Ikram KAMMOUN, Afef BEN HALIMA, Selem KACHBOURA
08:30 - 17:40 #11423 - Penetrating chest trauma caused by a police bean bag weapon.
Penetrating chest trauma caused by a police bean bag weapon.

Background

To temporarily disable an aggressive suspect for arrest, the Special Weapons and Tactics (SWAT) -team can use a bean bag gun. The bean bag is considered to be a non-lethal weapon and consists of a rounded bag of small lead bullets fired from a caliber 12 shotgun. This ammunition is intended to not penetrate the body, but to deliver a solid blow, with energy comparable to the punch of a professional boxer. This case report describes a patient with more serious injuries caused by a bean bag gun.

Case Summary

A 49 year old man known with a schizoaffective disorder, bipolar disorder, cluster B personality disorder and alcohol abuse had locked himself in his house and threatened to stab himself with a knife. He was overtaken by a SWAT-team using a Taser gun and was shot 3 times with a bean bag. After arrest he was presented at the emergency department and assessed according to the Advanced Trauma Life Support protocol. On physical examination, vital signs were stable. There was a hematoma and skin defect on the left apical thoracic side with the ribs visible inside the wound. There was no active bleeding. There were also large hematomas and excoriations on the left lower thoracic side and at the ventral side of the left shoulder. CT thorax showed a penetrating wound at the left ventral thorax wall at the level of costa 1, with fractures of costa 3 and 4, as well a contusion of the left lung and a small ventral pneumothorax. There was no intra-abdominal traumatic injury. X ray of the left hand showed a fracture of de midphalanx of the second finger with dorsal angulation. Ethanol was 1.6 g/L in a venous blood sample. Patient was treated with kefzole intravenously, tetanus immunization and was admitted at the medium care ward. The wound on the left side of the thorax was rinsed twice a day and treated with flaminal forte and covered with kerlix dressings. Follow up of the wounds was done at the outpatient department were necrosis and old clots were removed a few days later.

Conclusion

There are only a few publications about the use of bean bags and associated injuries. The use of bean bags is intended to be a non-lethal weapon. With this case report we will create awareness that the use of a bean bag can be associated with life threatening injuries.  


Patty BEENTJES, Christian HERINGHAUS (Leiden, The Netherlands)
08:30 - 17:40 #11955 - Performance of early change of cardiac output in the diagnosis of acute heart failure (AHF) in patients with acute dyspnea.
Performance of early change of cardiac output in the diagnosis of acute heart failure (AHF) in patients with acute dyspnea.

Purpose: To evaluate the performance of cardiac output (CO) change with dynamic and pharmacological maneuvers in the diagnosis of AHF in patients admitted to emergency department (ED) with acute dyspnea.

Methods: A prospective study conducted in the emergency department (ED) including patients over 18 years admitted for acute dyspnea. We measured CO using thoracic bio impedance: at baseline, during supine position (SP), leg rising (LR),under Valsalva maneuver (VM) and after administration of sublingual nitroglycerin (NTG test). Heart failure (HF) is defined on the basis of clinical findings, serum levels of pro-BNP and echocardiographic criteria.

 

Results: 395 patients were included, 212 patients with HF. Cardiac output at baseline was higher in the non-AHF group (p <0.01). The effects of the various maneuvers on COwere summarized in the figure.

Conclusion:Early changes of cardiac output with VM and NTG can be a simple method to recognize HF in patients who are admitted to ED for acute dyspnea.


Kaouthar BELTAIEF, Mariem BEN MARZOUK, Zied EZZINA, Malek ECHEIKH, Wafa ZHANI, Adel SEKMA, Med Amine MSOLLI, Med Hbib GRISSA, Wahid BOUIDA, Nader BEN OTHMEN (Monastir, Tunisia)
08:30 - 17:40 #11106 - PERICARDIOCENTES GUIDED BY A PORTABLE V SCAN: THE FUTURE AND SECURITY IN OUR POCKETS.
PERICARDIOCENTES GUIDED BY A PORTABLE V SCAN: THE FUTURE AND SECURITY IN OUR POCKETS.

Introduction

Pericardiocentesis (PC) was first described by Skoda in 1841 and great improvement of the technique has occurred since then. Fluoroscopic guidance and electrocardiographic (EKG) needle monitoring have been used to improve the safety of PC, although complications like damage to the liver, myocardium, coronary arteries and lungs have been reported. Echocardiography (ECHO) guided PC was developed in the late 1970s. This is a widely used technique nowadays. The technique emphasizes identifying the entry site and attaining maximal fluid collection removal by chasing the best window and trajectory for needle entry.

Case Report

A 70 years old white male came to the ER with great intensity (7/10) chest pain in the left hemithorax, which worsened with deep ventilation and body motion, and was characterized as a non-coronary pain. Nausea, dyspnea, palpitations, 10kg weight loss, fatigue, indisposition and dry cough were present. He had hypertension treated with Losartan. Physical examination revealed a regular heart rate (HR) of 180, blood pressure of 90/60 mmHg with paradoxical pulse, hypophonesis of heart sounds, crackles on the left pulmonary base and jugular venous distension. An EKG was immediately performed (atrial flutter with high ventricular response and electrical alternans) followed by a V scan ECHO portable (large pericardial effusion with heart swing and cardiac tamponade). PC with local anesthesia was performed in the ER with needle entry in the subxiphoid left region guided by V-scan ECHO portable, using the Seldinger technique and leaving a permanent catheter for subsequent withdrawals; drainage obtained 530 ml of sero-hematic fluid. PC was performed without intercurrences and shortly after drainage the patient had significant improvement in HR (to 120) and normalized his blood pressure with right ventricular expansion. Amiodarone 300mg was started intravenously. The patient evolved to stable status and was investigated for secondary causes, which discovered liver nodules.

Conclusions

Growing disponibilty of ECHO technology with pocket devices is specially suited to emergency care even in far away places. A trained ER physician is able to accelerate diagnosis and treatment, especially when life saving situations arise that need fast interventions.


Luis Felipe Silveira SANTOS (Ribeirão Preto, Brazil), Beatriz De Paiva Abrahão SANTOS, Fernanda Maia ARAUJO, Marcella Da Costa BARROS, Rosemary Aparecida Furlan DANIEL, Caio Garbeloti Soares SOUZA, Camilla Dos Santos VELOSO, Iran Gonçalves JUNIOR, Antônio Carlos CARVALHO
08:30 - 17:40 #11621 - Persistent complete heart block following blunt thoracic trauma.
Persistent complete heart block following blunt thoracic trauma.

  

Introduction 
Cardiac involvement  is frequent in blunt thoracic trauma. Most commonly involved structures are the RA and RV.Conduction abnormalities have also been documented with complete heart block being the most rare one. We present the case of a 18 year old gentleman that developed complete heart block and acute RV failure following road traffic accident.
Case presentation 
A 18 year sold gentleman was admitted to our hospital following a road traffic accident. He  was hit by a vehicle traveling at 70 mph while he was walking along the motorway. He sustained multiple injuries in his lower extremities and bilateral pneumothoracies due to rib fractures. He was hemodynamically unstable on arrival and with ongoing CPR emergency laparotomy was performed followed by pericardiotomy which did not reveal an intra abdominal bleeding or pericardial effusion. Despite inotropic support he developed episodes of profound bradycardia with prolonged episodes of ventricular standstill. A 12 lead ECG demonstrated complete heart block with evidence of right heart strain. An externalized passive fix lead was placed in the RV apex through the R subclavian approach. One week later the ECG showed sinus rhythm with LBBB.Pacemaker interrogation confirmed absence of RV pacing in the preceding 48 hours. The externalized system was therefore removed and discharged to the orthopaedic  team for management of his lower extremities fractures. 
Discussion 
Complete heart block in the most rare conduction abnormality documented in blunt thoracic trauma. Although the AV node recovered it did required  RV pacing for 1 week. This is contrary to the majority of CHB cases described in the literature where the conduction abnormality is transient. Proposed mechanism is oedema around the conductive system which may resolve completely or lead to various degrees of fibrosis. Of note our case was complicated by acute RV failure with dilated RV and D septum in diastole evident in transthoracic echo. The recovery of the conduction abnormality followed the recovery of RV function probably due to different healing properties of the myocardium and conductive tissue. Given the ECG and echo finding the possibility of traumatic dissection of RCA was also considered but elected not to proceed to coronary angiogram as the RV function had completely recovered. 
Conclusion 
Conduction abnormalities are an important cause of hemodynamic instability in blunt thoracic trauma.In vast majority are transient but externalized pacemaker system may be needed to allow recovery of the conductive tissue.


George BESIS (Swansea, United Kingdom), Konstantinos KARMPALIOTIS, Brown NIGEL
08:30 - 17:40 #11094 - Persistent hyper-acute t-wave revealing sclarovsky-birnbaum phenomenon.
Persistent hyper-acute t-wave revealing sclarovsky-birnbaum phenomenon.

Introduction :

Hyper-acute T-wave is  a transient  electrical feature wich often appears in the very early stage of coronary occlusion and leads rapidly to the electrical ST elevation myocardial infarction (STEMI). This electrical feature should lead to a close monitoring of electrocardiogram. However, persistent  hyperacute T-wave without evolution to rising ST segment was described in the literature.

Case report :

We report a case of a 32-year old man, smoker, who presented to the emergency department (ED) for retrosternal chest pain evolving by paroxysmal recurrent episodes with last exacerbation within 3 hours before ED visit. On examination, patient was counscious with pain scale estimated about 60/100 mm.  Vital signs were correct with no haemodynamic deterioration. The electrocardiogram (EKG) on admission showed a regular sinusal rythm with an hyperacute T-wave in the antero septal leads. Patient was admitted to the emergency room for monitoring , decision making and treatment. Repeated EKGs showed no evolution to a STEMI but persistant Hyperacute T-wave on same leads. Non-STEMI diagnosis was considered and patient was managed by anti-ischaemic drugs, double anti-platelets agents and effective anticoagulation. Biology analysis noticed a normal kaliemia= 4 mmol/l. Furthermore, echocardiography objectived impaired wall motion and low left ventricular ejection fraction = 35%. Patient was transferred urgently to the cath-lab where coronary angiography revealed thight thrombotic stenosis of the proximal anterior interventricular artery with persistent collateral retrograde vascularization.

Conclusion :

Persistent Hyperacute T-wave is rare known as sclarovsky-birnbaum phenomenon with grade 1 ischaemia. This entity has been explained by persistent collateral retrograde vascularization with adequate minimal myocardial perfusion wich leads to transmural ischaemia without evolution to a STEMI. This phenomenon was described often in some cases of critical occlusion of anterior interventricular artery.


Hamed RYM (Tunis, Tunisia), Mohamed KILANI, Imen MEKKI, Sarra JOUINI, Maroua MABROUK, Abir WAHABI, Héla BEN TURKIA, Chokri HAMOUDA
08:30 - 17:40 #11140 - Peter and the Wolf – a rare case of wild animal bite.
Peter and the Wolf – a rare case of wild animal bite.

Animal bite wounds are quite frequent and most of them are caused by domestic pets. Wild animal bites naturally reflect on local fauna, and for example in United States rabies plausible wild animal bites are most commonly caused by raccoons and bats. In addition to tetanus vaccinations or boosters, broad-spectrum antibiotics are often needed.

 Our case: a 7 year old, healthy boy was visiting local Wild Animal Park with his parents and siblings.  The family has husky-dogs as domestic pets. Somehow the boy got around the wooden 1.5m high safety fence surrounding the wolf cage. The cage was double-checked with metallic mesh-fence. Since wolves resemble huskies, the boy had no fear for them and walked near the mesh-fence, when suddenly one of the wolves grabbed the boy’s right hand and wrenched it through the mesh. Another wolf bit the boy to right arm. He was released by his father who got minor injuries to his hands. The boy was hemodynamically stabile, the wound was washed, protected and splinted, and he was transferred by ambulance helicopter to the nearest tertiary hospital.
On arrival (3 hours from the accident) a hand surgeon, a plastic surgeon and a pediatric surgeon were available. A near-circular antebrachial wound was inspected and washed. A tetanus booster was given and antibiotics were started intravenously: a combination therapy of ceftriaxone and metronidazole was used. The extension movement and sensory innervation of the thumb were diminished, but sedatives and painkillers made reliable examination difficult. Arteries were intact. Gustilo grade 3b Monteggia fracture was inspected on X-rays. Rabies-imovax series was given on days 0, 3, 7 and 14.

The wound was revised the same day at the operation room under general anaesthesia and fracture was fixed with a K-wire. Revision surgery was performed on the third and fourth day with a plate fixation of the fracture. Skin graft was placed on the fourth day with no signs of primary infection inspected. Even though the wound was near-circular, most of the muscles were vital.

Antibiotics were used for one week. After one month no sign of infection was discovered and skin graft was healing well. The patient had minor motoric problems with wrist movement, mostly related to posterior interosseous nerve, but the prognosis on the function of the arm and hand is good. He is currently in a psychologist’s care for post-traumatic stress disorder.

As wild animal bites are rare, rabies-vaccination and tetanus-booster need to be remembered. Rabies virus can be neutralized up to a point with soap, and if a possibility of rabies is suspected, the wound should be washed with soap at the event site. There is no specific recommendation for wild animal bites, but usually domestic cat bite prophylaxis is suitable, covering both aerobic and non-aerobic microbes. In open fractures, the wound should not be closed; usually wound is revised at least once or twice before coverage can be planned. 


Sally JÄRVELÄ, Matti KARPPELIN, Frederick WEITZ, Satu-Liisa PAUNIAHO (Tampere, Finland)
08:30 - 17:40 #11580 - Physiotherapist in the emergency department.
Physiotherapist in the emergency department.

Introduction: Emergency Phsiotherapist can idependently assess musculoskeletal problems, order/interprete investigation in the Emergency Department. 1,2

Methodology: Four week piolt in the Cambridge Emergency department with 2 physiotherapist. This was a seven day service from 1PM to 8PM. Data collected by retrospective chart review

Results: 169 patients seen out of which 138 were seen by the Physiotherapist. 76/138 seen soley by the physiotherapist without any other clinical invovlment. There was good patient satisfaction and no adverse incident during the piolt period. 

Conclusion: Piolt data and feedback suggest that Physios working in the Emergency Department could see a significant number of the musculoskeltal patients. 82% of the Musculoskeletal complaints seen in ED could have been managed by emergency physiotherapist. 

Future Plan: We are running a further longer piolt to confirm or refute the benefits of physiotherapist in the emergency department. 

Reference: 

1. Advanced Practitioner: Accident and Emergency (A&E) and physiotherapy . Case study http://www.nwwmhub.nhs.uk/media/142869/adp-009-musculoskeletal-emergency


2. Anaf S, Sheppard LA. Describing physiotherapy interventions in an emergency department setting: an observational piolt study. Accident and emergency nursing. 2007 Jan;15(1):34-3. McClellan CM, Cramp F, Powell J, et al.

 


Alexander TARRANT, Goergia SINFIELD (Cambridge, United Kingdom), Conor GALLAGHER
08:30 - 17:40 #11309 - Physiotherapy and Medical Social Work Referral, an Audit.
Physiotherapy and Medical Social Work Referral, an Audit.

Introduction: Emergency Departments(ED) are seeing  an increase in patients with chronic disease.  Many Emergency Departments do not have access to care services like Physiotherapy, Medical social work or these are only available for short periods during the week. Theses services can reduce admissions, so we audited our patients to see who would have benefitted from such services.

Methods: In a retrospective study, therapy or we studied the records of all the patient coming to the department in one week from December 5th to December 11th.  Those who would benefit from Physiotherapy, Medical Social Work or Occupational therapy or whose admission may have been avoided are selected.

Results: . We found  130 patients that would have benefitted from referral,  18 patients each day. About 37% of them were aged 76 or above.  More than two third of them arrived between 9 am and 4 pm. Almost all would have benefitted from  Physiotherapy and half from  Medical Social work if these services were available.

Conclusion: We need a Physiotherapist and Medical Social work team services in ED at least till 10 pm in the evening if not 24 hours a day, every day. This will improve patient care and avoid unnecessary admissions to inpatient services.


Zahid KHAN (Galway, Ireland), Fiona FAUGHNAN, Lynn SPOONER, Brian MCNICHOLL
08:30 - 17:40 #11506 - Piriformis abcess. A very unusual cause of sciatica.
Piriformis abcess. A very unusual cause of sciatica.

Introduction: Piriformis pyomiositis is a rare cause of sciatic pain, caused by an acute bacterial infection due to Staphylococcus aureus.

Case report: We report a 46 years old female, working as a dressmaker, who presented to the emergency department (ER), for the fourth time in the past ten days, complaining of right gluteal pain, refractory to painkillers and associated with fever in the last four days. The patient didn’t refer any other symptoms. She was allergic to penicillin, active smoker and had a medical history of hypertension and anxiety. Previously she received treatment for a dental abscess six months earlier and three months prior for an anal fissure. She was currently treated with clonazepam, enalapril, hydrochlorothiazide and analgesics. Ciprofloxacin was started two days before her last visit to the ER, as pyelonephritis was considered as diagnosis.  The patient had no history of trauma, cutaneous injuries, any other known infections, nor intramuscular injections.

Examination revealed a tender abdomen with pain in hypogastric and right lower quadrant, with no sign of peritoneal irritation. Deep tenderness was provoked when pressure was applied on the gluteal area and an anal fissure was identified, with no external fistula. Routine blood test shown white -cell count 23,800 per cubic millimiter  and an elevated C-reactive protein 30.94 mg per liter, urine test was normal. Computed tomography demonstrated an abscess of the piriformis muscle (20x40mm), right adnexal thickening and an nonocclusive thrombus of the iliac vein.

The patient was admitted and treated with a course of intravenous antibiotics (initially vancomycin, gentamycin and metronidazole) and low weight heparin. Blood culture were positive for Streptococcus anginosus and after sensitivity was determined, she continued receiving intravenously vancomycin. No gynecological evaluation showed no pathology and endocarditis was excluded after performing a transthoracic echocardiography. The patient was discharged after a noneventful recovery.

 

Conclusion: The piriformis muscle abscess is uncommon and its diagnosis should be considered in patients with sciatic pain, fever and leukocytosis. Bacteremia is the usual source. Streptococcus anginosus, a subgroup of viridans family is considered part of the normal flora of the oral cavity and gastrointestinal tract. It may provoke blood stream infection and distant abscesses and its treatment involve antibiotics and drainage. 


Claudina REVOL (Palma de Mallorca, Spain), Bulilete OANA, Monica MARÍN, Germán FERMIN GAMERO, Esperanza RIUTORT THOMAS, Carmen RODRIGUEZ OCEJO, Bernardino COMAS DIAZ
08:30 - 17:40 #11738 - Place of registers in emergency practice assessment Example of the ReSCUS registry in the short- and medium-term follow-up of STEMI.
Place of registers in emergency practice assessment Example of the ReSCUS registry in the short- and medium-term follow-up of STEMI.

regestries are currently used for continued assessment of our medical practice. In an attempt to improve the management of patients with ST-segment elevation myocardial infarction (STEMI),our registry has been  established (ReSCUS).

We aimed To assess contemporary data on epidemiology, management and outcomes of patients with STEMI, to evaluate our practices, their impact on intra-hospital prognosis, at 6 months and 1 year. We assessed our adherence to the international guidelines .

METHODS:

We performed an observational study of 103 patients hospitalised for ST-segment elevation myocardial infarction (STEMI) enrolled in our Public General hospital from february  2014 to February 2015 .

RESULTS:a  total of 103 patients were admitted for ST elevation myocardial infraction (STEMI). The mean age was  62 years with a great gender predominance (sexe ratio= 5.43). Smoking was the most common risk factor (53.4%). The mean time of first medical contact after symptoms onset was 288± 180 mn. Only 19.4% of these patients contacted a physician within 60 min of symptom onset. 14,6% of patients arrived by EMS transport. The mean time of the first ECG was 43 ± 32mn.  . Reperfusion therapy was administered in 74% of patients (thrombolysis 10.6%, primary PCI 89.3%, and PCI after thrombolysis 2.9%).Median time from the onset of symptoms to thrombolysis  was 122 mn .Median time from the onset of symptoms to invasive treatment was 388mn . In-hospital mortality was 8.74%.Flow up was conducted at 30 day,6 mounths and 1 year post ED index admission to identify Major adverse cardiac events.conclusion :The data in our registry encourages us to further improve our management of STEMI. Efforts should be made to respect the recommended timelimits  for a better future prognosis. 

 

 


Sana MABSOUT, Asma ZORGATI, Houda BEN SALAH, Chawki JEBALI, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
08:30 - 17:40 #11704 - Plant-related Life Threatening Event; Sage Oil Toxicity.
Plant-related Life Threatening Event; Sage Oil Toxicity.

Background

The use of herbal products has increased gradually as part of the alternative and complementary medicine. Currently, families access these products upon physician advice or after their search in the web environment. The use of these products may cause serious neurological and respiratory complications in the neonates and infants. Herein, we present an infant who was rushed to the emergency department (ED) due to respiratory arrest.

Case Report

A 40-day-old girl was brought to the ED due to cyanosis and loss of consciousness. The family reported that the patient stared her eyes half an hour for about 15 min and developed tonic contractions in the entire body and stopped breathing. Her past medical history revealed that the patient was born vaginally at term; no complication occurred, and there was no history of disease or trauma and she continued breastfeeding.

At the ED, the patient had altered mental status, unresponsive to painful stimuli, irregular breathing was present, and there was a generalized tonic seizure activity. Vital signs were as follows: pulse rate, 180 bpm; respiratory rate, 12/min; temperature, 37.5 °C; oxygen saturation, 77%; and blood glucose, 150 mg/dL. Endotracheal intubation was performed; subsequently, rectal diazepam 5 mg (Diazepam Desitin® rectal tube 5mg) was administered. Following this administration she kept seizing within 10 minutes and intravenous midazolam 0.1 mg/kg (Dormicum® 5 mg/5ml) was given to control the seizure activity. Then her seizure was stopped.

Sage oil is in volatile form and it is recommended to apply 1-2 drops on plantar and tummy region of the body by the massage for the treatment of infantile colic. However, her mother misused the drug for her baby and administered one teaspoon of sage oil by oral way two hours before seizure activity. On the fourth hour of admission, her spontaneous respiration was sufficient; she was raised and experienced no recurrence of seizure. Her neurologic examination was completely normal. Electroencephalography (EEG) showed no epileptic focus and revealed normal findings. No abnormality was found on cranial magnetic resonance imaging (MRI) and other biochemical tests. The patient was discharged at the end of the 24-hour follow-up period in the ED. At one month, she showed normal neurodevelopmental milestones and remained free of seizures

Conclusion

In conclusion, not only seizures but also life-threatening events may develop by using sage oil in infants. Pediatricians must keep in mind that the use of such herbal medicines may also result in respiratory arrest subsequently to status epilepticus. 


Caner TURAN (ISTANBUL, Turkey), Ali YURTSEVEN, Eylem Ulas SAZ
08:30 - 17:40 #11810 - PNEUMONIA STRIKES: Infection reports in young patients over the past three years in Sibiu Emergency Room.
PNEUMONIA STRIKES: Infection reports in young patients over the past three years in Sibiu Emergency Room.

INTRODUCTION

Pneumonia is one of the most common health problems affecting all age groups around the world. It is an acute respiratory disease that is usually caused by bacteria but it can also be caused by other infectious agents such as fungi, parasites and viruses.

Therefore, the aim of this study is to observe the frequency of interstitial and lobar pneumonia in population, pneumonia age, sex, origin distribution.

MATERIAL AND METHODS

This retrospective observational study is performed on a total of 190,864 patients, presented at the UPU-SMURD of Sibiu County Emergency Clinical Hospital, between 01.01.2014-31.12.2016.

RESULTS

Of the patients presented during the study at UPU-SMURD Sibiu, 2270 (1.19%) were diagnosed with pneumonia; Of these, 1107 (48.77%) were women and 1163 men (51.23%).

1350 (59.47%) of patients come from urban areas and 920 (40.53%) from rural areas.

The distribution per year was as follows:

2014 - 725 (31.94%) patients (335 women, 390 men),

2015 - 741 (32.64%) patients (377 women, 364 men),

2016-804 (35.42%) patients (395 women, 409 men).

We divided the patients into the following age groups:

18-29 years - 218 (9.60%) patients,

30-39 years - 227 (10.00%),

40-49 years - 285 (12.56%),

50-59 years - 267 (11.76%),

> 59 years - 1273 (56.08%).

During the study:

833 (36.70%) of patients were diagnosed with Interstitial Pneumonia, of which 471 (56.54%) required hospitalization, the others starting with recommendation;

1199 (52.82%) patients were diagnosed with Pneumonia lobara, of which 897 (74.81%) required hospitalization, resting with recommendation;

238 (10.48%) patients experience Pneumonia with associated pathology.

CONCLUSIONS

 Of the patients presented at UPU-SMURD Sibiu, during the study, 1.19% were diagnosed with Pneumonia.

Distribution by gender is approximately equal, slightly higher in male patients (51.23%) and in urban areas (59.47%).

56.08% of cases of Pneumonia are diagnosed in patients over 59 years of age, with the remainder being relatively evenly distributed among 19- to 59-year-olds, with a slight decrease in the 18-29 age group.

More than half of the pneumons (52.82%) were lobar, most of them requiring hospitalization.


Virgiliu Cezar BOLOGA, Bianca Mariana BAILA (Sibiu, Romania)
08:30 - 17:40 #11720 - Pneumothorax Secondary to Inhalation of Corrosive Substance.
Pneumothorax Secondary to Inhalation of Corrosive Substance.

Introduction

In this paper, we present a case of pneumothorax which occurred with toxic gas inhalation after use of bleach and lime remover together.

Case
A 22-year-old male patient presented to our emergency service with complaint of shortness of breath 1 hour after cleaning his bathroom with bleach and lime remover together. The patient who had no known disease or drug use, had a history of smoking for 5 years. His baseline vital signs were PO2: 88 mmHg, pulse rate: 110/min, respiratory rate: 24/min, blood pressure 100/60 mmHg and body temperature: 36.8 °C. In his physical examination he was conscious, cooperative and oriented and his Glasgow Coma Scale was 15. He had bilateral rhonchus in his respiratory examination and both hemi-thoraces contributed equally to respiration. Cardiac sounds were rhythmic and no murmur was heard. Other systemic examinations were natural. His EKG showed sinus tachycardia. In his chest X-ray, there was an increase of consolidation in hilar region and we observed no pneumothorax or atelectasis. His cardiothoracic index was normal and sinuses were clear. Oxygen therapy was started immediately and patient was monitored, then laboratory tests were requested after establishing a vascular access. Inhaler beta-2 mimetic was administered three times with 15 minutes intervals and a single dose of inhaler steroid was administered. Intravenous 80 mg prednisolone was also administered along with 20 mg pantoprazole. The patient who partially replied to symptomatic treatment had 18/min respiratory rate, %92 saturation without oxygen support and 108/min pulse rate however he still had rhonchus. Because of his partial response to initial treatment, inpatient treatment was suggested. The patient who was hospitalized in Chest Diseases ward was discharged 1 hour after his hospitalization at his own request. Yet patient applied to emergency service again with shortness of breath 4 hours after his discharge. In his second appearance, he had 26/min respiratory rate, %85 saturation, 124/min pulse rate. He had bilateral rhonchus. Patient again received oxygen treatment, inhaler beta 2 mimetic and steroid treatment and control chest x-ray was requested. After observing peri-cardiac hypodense areas in his control chest x-ray, a thorax tomography was requested with oxygen support. Bilateral pneumothorax, pneumo-mediastinum and subcutaneous emphysema were observed in his thorax tomography. Patient was consulted with thoracic surgery and bilateral tube thoracostomy was placed. Patient was referred to a tertiary healthcare center with tube thoracostomy and was cured without any surgical procedure after follow-up with bilateral tube thoracostomy.


Burak ÇELIK (İstanbul, Turkey), Sercan EROĞLU, Hacı Mehmet ÇALIŞKAN, Süleyman ERSOY, Yusuf DURSUN
08:30 - 17:40 #9841 - Point of Care Ultrasound (PoCUS) saves lives ; A case presentation.
Point of Care Ultrasound (PoCUS) saves lives ; A case presentation.

Background: Utility of Point of care ultrasound (PoCUS) in critically ill patients and resuscitation has revolutionised the practice of Emergency medicine.Focused echocardiography in emergency Life support (FEEL) is increasingly used in the emergency setting, with an ALS compliant FEEL algorithm proposed as an adjunct in peri-resuscitation care. 

Aim:We describe the case of a pulses electrical activity (PEA) arrest from cardiac tamponade resulting from an aortic dissection in which PoCUS assisted in diagnosis and treatment by pericardiocentesis in the emergency department (ED).

We also recommend three views which can be performed when TAD is suspected.

Conclusion: Focused ultrasound is increasingly used in the emergency setting, with an ALS-compliant focused echocardiography algorithm proposed as an adjunct in peri-resuscitation care can increase survival rate and improve patient care.

Also three recommended views increase the  chance of diagnoses of TAD.


Dr Pourya POURYAHYA (Melbourne, Australia), Alastair MEYER, Hwee Min LEE
08:30 - 17:40 #11227 - Point of care ultrasound in a septic patient in the emergency room.
Point of care ultrasound in a septic patient in the emergency room.

Purpose: Emphysematous cholecystitis (EC) is an entity with high morbidity and mortality, and therefore require a diagnosis agile and dynamic, allowing appropriate management to avoid complications. The emergency ultrasound (US) allows a versatile and comprehensive management, improving the prognosis of this disease in the majority of cases.

 

Material & Methods: a patient with abdominal pain, with a final diagnosis of an EC assessing US performed by emergency physician.

 

Results: We report the case of a 72 year old patient with prior stroke without sequelae and hypertensive, with abdominal pain of 7 days duration, high fever and bilious vomiting, and clinical condition of septic shock. The emergency physician performed a bedside ultrasound that showed a thickened gallbladder wall (8 mm), well-circumscribed, oval, distended and gas in the same wall, compatible with emphysematous cholecystitis. Support measures were initiated, antibiotics and emergency surgery was indicated.

 

Conclusions: EC is a rare entity that represents 1% of all cholecystitis, clinically indistinguishable, but with a worse prognosis (25% mortality) and more complications. The use of abdominal US in ER allows for both a rapid and versatile, with proper treatment start, this being vital to good patient outcomes.

Incorporate Emergency ultrasound may facilitate the early diagnosis of acute cholecystitis , preventing its severe clinical complications and providing greater patient safety. Therefore, the authors believe that the use of abdominal ultrasound in the emergency should be extended to all  because it allows us a quick and versatile diagnosis, appropriate treatment with early onset with severe patients , as in the case presented, this being vital for a better prognosis and a good outcome for our patients.


Francisco LUQUE SÁNCHEZ (Seville, Spain), Margarita ALGABA-MONTES, Alberto Ángel OVIEDO-GARCÍA
08:30 - 17:40 #10918 - Point of care ultrasound in emergency settings in a jaundice patient.
Point of care ultrasound in emergency settings in a jaundice patient.

Purpose: Abdominal ultrasound has proven to be a useful, safe, versatile, with appropriate experience, help earlier diagnosis and comprehensive management of patients seen in the emergency department. We present a case of Jaundice by biliary stent obstruction in patient with pancreatic neoplasia, through a bedside ultrasound by Emergency Physicians.

Material & Methods: We report the case of a patient of 64 years with pancreatic neoplasia bearer of 8 French plastic stent by ERCP for biliary drainage for 6 days as palliative treatment, admitted in Emergency Room by jaundice and abdominal pain in epigastrium.

Results: On arrival had malaise, was hypotensive, febrile, tachycardic and jaundice universal. The analyzes highlighted a bilirubin of 9.52 at the expense of direct fraction (8.60 mg / dl), and 22.500 leukocytes with neutrophilia. She underwent a bedside abdominal ultrasound where we found a central hyperechoic endoprosthetic image with acoustic shadowing, compatible with biliary litiasis. The patient was derived for urgent endoscopic retrograde cholangiopancreatography, sphincterotomy, removal of prosthesis, washing and placement 10 French prostheses, allowing a favorable evolution of the patient discharged within 72 hours without complications.

Conclusion: The use of stents as temporary drainage of the bile duct as palliative treatment for pancreatic head tumors is an effective, useful, safe and effective, it also represents a decrease in short-term mortality in these patients, and survival increased disease-free. The use of ultrasound in emergency allows us greater agility and speed in the diagnosis of prosthetic obstructions, allowing a more integrated management of the same. As shown in the case that concerns us a bedside ultrasound by Emergency Physicians favored a quick and agile diagnosis of biliary sepsis patient suffering, allowing prompt treatment and an early solution to the problem.


Margarita ALGABA MONTES (Sevilla, Spain), Alberto Ángel OVIEDO GARCÍA, Francisco LUQUE SÁNCHEZ
08:30 - 17:40 #11591 - Point-of-care lab in out-of-hospital resuscitation: Feasibility and value of venous blood gas analysis on scene.
Point-of-care lab in out-of-hospital resuscitation: Feasibility and value of venous blood gas analysis on scene.

Background:

The treatment of a cardiac arrest requires the targeted search for causes and worsening co-factors as recommended by the current guidelines with the “4 H and 4 T approach”. Laboratory makers may be an important issue and can be determined with mobile blood-gas–analyzers on site during resuscitation measures. This study examines the frequency and relevance of pathological laboratory finding in venous blood gas analysis (VBG) in out-of-hospital cardiac arrest (OHCA).

Methods:

A retrospective evaluation of all out-of-hospital resuscitations in a county of 252,000 inhabitants was undertaken from 01.05.-31.07.2016. A mobile analyzer (Alere epoc®) was available in all missions and patients with return of spontaneous circulation (ROSC) were admitted to a single university cardiac arrest center. All prehospital VBGs were evaluated for the frequency of pathological values and interventions based on these findings.

Results:

In the study period n=60 out-of-hospital resuscitations were performed, a VBG was sampled in n=24 patients and analyzed on site. In n=21 (88%) patients base excess (BE) was below -3 mmol/l, hyperkalaemia was found in n=5 (21%), hypokalaemia in n=6 (25%) and elevated lactate with a median of 7.6mmol/l in n=23 (96%). N=11(46%) patientes recieved buffering and n=6 (25%) an electrolyte-specific therapy on site. N=17 of the 24 patients with VBG could be admitted to hospital with return of spontaneous circulation, n=11 patients were discharged alive.

Discussion:

Sampling and analysis of VBG appears to be feasible during prehospital resuscitation. In the majority of patients relevant pathological findings could be seen and treatment according to guidelines could be started already on scene. Further studies are needed to assess the influence on early VBG on outcome.


Susanne BETZ, Tobias GRUEBL, Martin SASSEN, Erich WRANZE, Heiko HARTMANN, Clemens KILL (Essen, Germany), Birgit PLOEGER
08:30 - 17:40 #11697 - Point-of-care testing in emergency medicine services – a narrative pilot study in Kanta-Häme, Finland.
Point-of-care testing in emergency medicine services – a narrative pilot study in Kanta-Häme, Finland.

Introduction

Point-of-care testing (POCT) for troponin in prehospital settings has been found reliable and feasible. Elevated troponin in prehospital setting contains diagnostic information being highly predictive of mortality in patients with a suspected myocardial infarction. The aim of this narrative study was to evaluate the use of POCT in EMS.

 

Materials and methods

Single POC-machine (i-STAT) was introduced in Riihimäki EMS, Kanta-Häme area, in the summer of 2016. Riihimäki EMS includes five EMS units. In this narrative study, we collected experiences of the staff working in the Riihimäki area after 6 to 9 months’ experience. Besides 15 paramedics, also two EPs working in a close contact with EMS were participating by telling own experiences.

The purpose of i-STAT was to verify and hasten the treatment of patients and confirm decision making by EMS staff. I-STAT measurements in our study included Troponin I (TnI), C-reactive protein (CRP) together with EC8+ study (sodium, potassium, chloride, anion gap, glucose, urea nitrogen, pH, pCO2, TCO2, HCO3 and base excess). Indication for TnI measurement was mainly chest pain without ST-elevation and symptoms lasting more than three hours.  Other POCs were taken after the measurements of vital signs (ABCDE, ECG, glucose), if the patient was in poor clinical condition. POCT was not needed in trauma patients or if the patient was clearly in the need of EMS transportation. On the other hand, patients obviously in good clinical condition and able to take care themselves were not in the need of POCT. The POC results were documented in EMS form.

 

Results

In the catchment population of 46 500, the number of i-STAT studies of a single POC machine had stabilized in a level of one to four per week. Negative TnI without ischemic changes in ECG supported EMS staff in the decision to avoid unnecessary ED visit of the patient. EMS staff felt, that EC8+ measurements most importantly fortified the decision of EMS to transport the patient to emergency department (ED). In some unclear clinical cases the TnI was measured together with CRP and EC8+. According to EMS staff, also some of these patients could be treated cost-effectively in destination without EMS transport. With the results of POCT, the consultations between EMS and the ED physicians were mutually noted to be of better quality than without POCs. When asked the most indications for the use of POCT, the leading symptoms and signs were chest pain, dyspnea, disturbance of vital signs, poor clinical condition, hemorrhage, vomiting or diarrhea and collapsing. No major technical issues were reported.

 

Conclusion

In this narrative study, the use of POCT was felt to give added value in evaluating patient’s condition and in expediting possible treatment by EMS staff. Some patients could even be treated in destination without transportation to the ED. According to the EMS staff, POC machines should be used in every EMS unit.


Markku GRÖNROOS (Hämeenlinna, Finland), Ari PALOMÄKI
08:30 - 17:40 #11154 - Polytraumatic patients from car accidents evaluated in Emergency Room department of Bucharest Emergency Clinic Hospital - a retrospective study.
Polytraumatic patients from car accidents evaluated in Emergency Room department of Bucharest Emergency Clinic Hospital - a retrospective study.

Background:

Worldwide trauma is a leading cause of mortality. Traumatic injuries range from minor isolated wounds to complex injuries involving multiple organ systems. All trauma patients require a systematic approach to management in order to maximize outcomes and reduce the risk of undiscovered injuries. According to the World Health Organization (WHO), road traffic injuries accounted for 1.25 million deaths in 2015, and trauma is expected to rise to the third leading cause of disability worldwide by 2030. Romania and Bulgaria are the countries with the highest number of road traffic deaths, almost double compared to the average recorded in Europe.

Participants and methods:

In this retrospective observational study, we collected the demographic data (e.g. age, gender, region, etc.) of all the poly-traumatic patients from car accidents presented to Emergency Clinic Hospital from Bucharest between January 2014 - December 2016. In order to evaluate the vital parameters we used the rapid test (e.g. GEM PREMIER 3500, SAMSUNG, SIEMENS, CONCILE, DPU-414 THERMAL PRINTER, URILYZER 100,GEM PREMIER 4000) and exhaustive analysis was made by the laboratory using different types of machines and technology (e.g. CELLTAC-F, VITROS_FS5.15, ACL TOP 500 etc.) to confirm the diagnosis. The data were statistically processed by SPSS ver. 20.

Results:

From a lot of 173 polytraumatic patients presented in the Emergency Department between 2014-2016, 129 of them had been resulted from car accidents: 44 patients in 2014, 43 patients in 2015, and 42 patients in 2016. In our lot, we observed that from 129 polytraumatic (68,2% men) the most of the polytraumatic patients had the age between 30 and 50 year (65.9%), followed by patients with ages under 30 (18,6%) and them above 50 years old (15,5%). From the monthly distribution, we have noticed that the highest percent of road traffic accidents were occurred in summer months (June, July, August). In our Emergency Department, 6 polytraumatic patients died, 3 were transferred to another hospital, 21 leaved ER and 99 have been hospitalized in: Orthopedics, Surgery and Neurosurgery. The most common injuries were: limb, brain, internal and head.

Conclusion:

The number of car accidents was constantly during every of the 3 years without any major fluctuation despite the decreased of reported car accident frequencies. Most of the patients were man with ages between 30-50 years old. The highest frequency of car accidents was throughout the month of June, July and August, during the summer holidays. The hospitalization of patients after ER were in: Surgery, Orthopedics and Neurosurgery.

Acknowledgments:

No potential conflict of interest relevant to this study.


Amal Antonia ARNAOUTE (, Romania), Oana Andrada ALEXIU, Bogdan Mihai OPRITA, Luisa Corina SIMION
08:30 - 17:40 #10867 - Portal vein injury. Report of a case treated by primary repair.
Portal vein injury. Report of a case treated by primary repair.

   Portal vein injury is a very rare condition, accounting 1% of patients who undergo emergency laparotomy for trauma. It is usually caused by penetrating trauma (90%) and has a high mortality rate, as it is very challenging to identify and repair that kind of lesion.

   A 43-year old male was transferred to the Emergency department in grade IV shock, with a penetrating trauma to the left lower chest (1cm stab wound in the 9th intercostal space). His breath sounds were equal bilaterally and the diagnostic peritoneal lavage revealed hemoperitoneum. While he was  transferred to the operating room for an emergency laparotomy, he had a pulseless electrical activity and responded to resuscitation.

   The midline incision revealed: Intraperitoneal haemorrage , a large hematoma in the porta hepatis and a laceration of the liver surface (l:3mm d:3cm). A Pringle manoeuvre was performed and a grade V vascular injury of the portal vein was identified. A primary repair was decided and the bleeding was controlled.  The duration of the operation was 90 minutes. Then the patient was transferred to the ICU.

   It is very important to be aware of the management options of the portal vein injury. A lateral venorraphy is the first option. In the unstable patient the ligation of the vein is preferable, as it is a viable option, provided that the hepatic artery is intact. Complications of portal vein ligation are rarely reported.

 


Paraskevi KARONA (Chania, Greece), Eleni TSAKIRAKI, Athina ANAGNOU, Georgios PETRAKIS, Spyridon KAVROCHORIANOS, Emmanouil CHARITAKIS, Pagona KASTANAKI, Athanasios KOURAKOS, Nikolaos KATSOUGKRIS, Miltiadis KASTANAKIS
08:30 - 17:40 #11709 - Post-myocardial infarction ventricular septal defect: report of a case.
Post-myocardial infarction ventricular septal defect: report of a case.

Male patient, 70 years. No medical history. Presents with It came to our emergency box of 15 days of evolution of dyspnoea progressive to make minimal efforts in recent days. Associated with several pillow orthopnea since 2 days ago and edematizacion of lower limbs.

Physical exam: Normotensive, tachycardia (140 pm), increased jugular venous pressure basal. Sat 94%. Afebrile. Cardiopulmonary auscultation: Rhythmic tones with systolic murmur, decreased  vesicular murmur; Abdomen: globular, no masses or organ enlargement, blumberg Murphy -; MMII; distal edema with fovea +, no signs of DVT. Complementary tests: Blood test showed no significant findings. ECG: flutter 140-150lpm. Chest x-ray showed a cardiomegaly and bilateral pleural effusion. Echocardiogram:Inferno-septal-basal aneurysm and Ventricular septal defect, probably secondary to silent infarction.

We contacted cardiac surgeon who goes to urgent surgical intervention. 

Discussion: The Ventricular septal defect is an uncommon complication (1-2%) of acute myocardial infarction, joining more than 80% mortality with medical treatment. Surgery is the treatment for this complication, but when this should be practiced early (< 2 weeks) also carries a high mortality rate (30-50%) and an incidence of significant residual defects exceeding the present 40%. 
El case shows the Percutaneous closure at an early stage and with good result of a CIV postinfarction.


Carmen Adela YAGO (Malaga, Spain), María Del Carmen RODRIGUEZ, Enrique CARO, Valentina MORELL JIMÉNEZ, Juan Antonio RIVERO GUERRERO
08:30 - 17:40 #11636 - Post-traumatic bilateral adrenal hemorrhage: a rare cause of adrenal crisis.
Post-traumatic bilateral adrenal hemorrhage: a rare cause of adrenal crisis.

Introduction: The incidence of adrenal hemorrhage following blunt trauma is very low (0.86%). Most adrenal injuries are unilateral and asymptomatic and associated adrenal insufficiency is uncommon.  Its mortality is generally predicted by the associated injuries and not by the adrenal injury itself. We describe a rare case of posttraumatic bilateral adrenal hemorrhage with adrenal insufficiency.

Case report: A 44 year old male patient was admitted to the emergency department after a high velocity motor vehicle accident. The primary survey showed multisystem injury including bilateral adrenal gland hemorrhage. The patient was hemodynamically stable and he was transferred to the Intensive Care Unit for further observation.  Within 24 hours he developed non fluid-responsive hypotension. Hypovolemic shock due to active hemorrhage was excluded. The adrenal function was assessed by determining serum values of adrenocorticotropic hormone (ACTH) and cortisol and a Synacthen® stimulation test was performed. Steroid replacement therapy was started with improvement of the hemodynamics. The tests revealed a primary adrenal insufficiency and steroids were continued.

Discussion: Due to their location deep within the retro-peritoneum, the adrenal glands are usually protected from traumatic injury. Although traumatic adrenal hemorrhage is uncommon, it is increasingly recognized due to more liberal use of computed tomography in stable blunt abdominal trauma. Most reported cases describe unilateral injury with predominance for the right adrenal gland. Unilateral injury is often asymptomatic although it is an indicator for severe trauma with mortality rates up to 32% due to associated injuries. Bilateral injury however, can present as an adrenal crisis with hypotension, metabolic acidosis and electrolyte disturbances.  A non-fluid-responsive shock in abdominal trauma should alert the clinician to consider a post-traumatic adrenal crisis as timely treatment is essential.

Conclusion: We present a rare case of bilateral adrenal hemorrhage following blunt trauma. Within 24 hours after presentation the patient developed a primary adrenal insufficiency responsive to steroid replacement therapy. Adrenal trauma is often self-limiting and asymptomatic. However, it should not be regarded as an incidental finding as bilateral hemorrhage can present with fatal outcomes if not treated timely.


Erwin SNIJDERS (Antwerp, Belgium), Koen MONSIEURS, Jan GIELEN, Philip VERDONCK
08:30 - 17:40 #11392 - Postdural puncture headache is not an innocent diagnosis.
Postdural puncture headache is not an innocent diagnosis.

Background: Patients with headache constitute up to 4.5 percent of emergency department (ED) visits. The differentiation of patients with life-threatening headaches is an important problem in EDs. Postdural puncture headache (PDPH) can be one of these life-threatening conditions. We intented to emphasize with this this case that PDPH may not always be an innocent diagnosis.

Case: A 24-year-old male patient was admitted to ED with a complaint of headache emerging after knee ligament surgery with spinal anesthesia 3 days ago. The patient also applied with the same complaint to our ED 1 day ago. Because of his non-pathognomonic brain tomography, he was discharged with suggestions of hydration and excessive coffee intake. The hydration was started and Theophylline was given intravenously. Brain MRI was planned. MRI showed dural enhancement and low set cerebellar tonsil (Arnold Chiari Type I) (Figure 1). The patient was admitted to the neurology clinic with low CSF pressure and pre-diagnoses of meningitis.

Discussion: Spinal anesthesia is widely used for many obstetric, gynecological, orthopedic, and urological operations. PDPH is a most frequent complication of spinal anesthesia. Postdural puncture headaches (PDPH) are not the privilege of spinal anaesthesia, as they can occur in various circumstances including Lumbal puncture, epidural anesthesia, surgical wound of the dura, spinal tap and/or myclography. PDPH result from the leakage of CSF via the dural hole, responsible of hypotension of CSF in the subarachnoid compartment. PDPH typically manifests as a postural, frontal, frontotemporal, or occipital headache, worsened by ambulation and improved by assuming the decubitus position, occurring within 48 hours after dural puncture. PDPH also needs to be differentiated from tension/migraine headache, aseptic or infective meningitis, cortical vein thrombosis, or cerebral/epidural hematoma, spinal abscess, intracranial mass lesion, cerebral aneurysm, cerebral edema, myofascial syndrome, transient neurologic syndrome or related symptoms, unspecific post-dural puncture lumbalgia, neural toxicity of the drugs, and anterior spinal artery syndrome, post-partum cerebral angiopathy and cerebral thrombophlebitis. Brain CT may not always be sufficient for diagnosis or differential diagnosis in these patients. As lumber punction may cause increasement of cerebellar herniation, patients should be assessed with MRI before the procedure and MRI should included sagittal sections in terms of cerebellar herniation. MRI may demonstrate: diffuse dural enhancement with evidence of a sagging brain; descent of the brain, optic chiasm, and brain stem; obliteration of the basilar cisterns; and enlargement of the pituitary gland.   

Conclusion: When assessing PDPH in emergency departments, accompanying life-threatening conditions should be considered and MRI should be planned in  emergency follow-up before performing LP for diagnosis/differential diagnosis


Figen COŞKUN (ISTANBUL, Turkey), Ömer YESILYURT, Oğuz EROĞLU, Sevilay VURAL, Ufuk ERGÜN
08:30 - 17:40 #11904 - Posterior reversible encephalopathy syndrome of multi-factorial cause: A case report.
Posterior reversible encephalopathy syndrome of multi-factorial cause: A case report.

Introduction:

Posterior reversible encephalopathy syndrome (PRES) is a rare neurotoxic disease characterized by an acute neuro-radiology syndrome with clinical presentation that typically includes acute hypertension, seizures and other neurological symptoms.

Herein, we report a case with an atypical clinical and radiological context of PRES.

Case report: 

A 30-year-old male patient, with a medical history of unmonitored asthma, was admitted in our critical care unit for severe acute asthma. The immediate management included mechanical ventilation, sedation, neuromuscular blockers, bronchodilators and corticosteroids.

At day 10 of hospitalization, he developed a septic shock with a starting point ventilator acquired pneumonia (VAP) and needing hemodynamic support by norepinephrine. The septic shock was complicated with haemophagocytosis syndrome.

During the evolution, we marked a multiple sudden blood pressure (BP) fluctuations under norepinephrine (systolic  BP varying from 75 to230 mmHg).

Shortly thereafter, he presented an epilepticus status treated by phenobarbital as an intravenous loading dose of 15 mg/Kg followed by 200 mg/ day orally. The cerebral computed tomographic(CCT) scan showed bi-parietal hematoma and bilateral posterior hypodensity associated to white matter edema. The diagnosis of PRES was suspected based on clinical arguments  and supported by the radiological appearance on cerebral CT. The diagnostic confirmation was provided by the cerebral MRI showing a bilateral hyper intensities involving posterior parietal and occipital lobes, typically in favor of the PRES.

Otherwise, there was no biological abnormality outside a low serum level of magnesium (0.28 mmol/L).  This leads to an interesting hypothesis that hypomagnesaemia may contribute in triggering the PRES by acutely raising the BP.

The outcome was fatal by refractory septic shock.

Conclusion:

Our case showed a PRES occurring from multiple circumstances.  The BP fluctuations under norepinephrin were the mainly factors in the development of PRES. Furthermore, hypomagnesaemia and haemophagocytosis syndrome predisposed to an increasing of the permeability of the blood-brain barrier that disturbs the cerebral regulation-self. Additional systematic studies are required to test theses later hypothesis.


Mohamed Amine KALLEL (tunis, Tunisia), Ahlem TRIFI, Foued DALY, Yosr TOUIL, Sami ABDELLATIF, Salah BEN LAKHAL
08:30 - 17:40 #11301 - Poultry perforation.
Poultry perforation.

The first case of oesophageal perforation was described by Dr Hermann Boerhaave in 1724 when Baron Han von Wassenaer, the Grand Admiral of Holland, experienced sudden and severe pain after violent, but minimally productive retching. A transverse tear of his distal oesophagus was noted on post-mortem examination and he had gastric contents within the pleural cavity. Transmural oesophageal rupture, more commonly known as Boerhaave syndrome, although rare, can be fatal. In modern medicine, the majority of cases of oesophageal perforation are due to iatrogenic interventions, but other reported cases include foreign body ingestion, malignancy or trauma. Patients can vary in their presentation with some being clinically very well, others requiring intensive resuscitation.

This case report describes the presentation of a 63 year old woman who attended the emergency department 2 days after choking on a chicken bone. The patient was clinically well, but she had significant abnormalities on her radiographic and haematological investigations. The authors wish to illustrate that subtle clinical signs of odynophagia and dysphonia should be acknowledged and taken seriously when taking histories from patients who have choked on a foreign body regardless of their clinical appearance as these signs can indicate potentially serious pathology.


Laura YELL (Preston, United Kingdom), Pollyanna HAYWOOD, Thomas MOORS
08:30 - 17:40 #10873 - Practices of injections safety: a clinical audit at emergency room of Alshifaa hospital in the Gaza-Strip.
Practices of injections safety: a clinical audit at emergency room of Alshifaa hospital in the Gaza-Strip.

Background:

A safe injection is one that does not harm the recipient, does not expose the provider to any avoidable risks and does not result in waste that is dangerous for the community.
This is the first clinical audit in the Gaza-Strip to observe the application of different protective practices while giving injections to patients.

Methods:

This was a prospective clinical audit conducted in the emergency room (ER) at Al-Shifaa Hospital from January to March 2017 according to WHO guidelines. The data was analyzed using SPSS program.

Results:

In total, 100 cases were observed, of which 40% were for venous access. Among the performers of injections, 50% were females. Sixty percent were nurses, 20% were medical students and 20% were nursing students. The overall compliance rate for all practices was 20%. It was noted that the highest compliance rate was among nursing students (p= 0.2, F= 1.7) and a higher rate was obtained among males than females (p=0.3, t= -1.13). Interestingly, the highest rate was observed for those in the 20 to 30 year age group (p= 0.4, F= 0.5).
The hands of the performer were visibly clean in all observations.  Only 20% washed their hands all only after patient contact. Although wearing non-sterile gloves is recommended for venous access, this was only done in 5%. Disinfecting skin with 60–70% alcohol-based solution was performed in all cases. However, inappropriate technique, touching the puncture site and no waiting for at least 30 seconds after disinfection were observed in 60%, 20% and 90% respectively. The needle and syringe were immediately discarded into a robust sharp container in 80% but recapping the needle using one-hand scoop technique was practiced in none of them while injecting blood into a laboratory tube while holding it with the other hand was done in 80%, which is not recommended, as it poses a risk for needle stick injury.

Discussion:

Infection control measures concerning the administration of injections is shockingly poor among all healthcare professionals, including those still in training, who should show higher guideline adherence. This was apparent in regard to protection of patients as well as self-protection.   The awareness of infection control and its key role in patient safety and prevention of healthcare associated infections falls significantly below acceptable standards.  As this is a serious shortfall in patient safety practices, it requires urgent address in form of implementation and training in infection control practices among healthcare staff.


Mohamedraed ELSHAMI (Gaza, Israel), Enas ALALOUL, Jomana HASHEM, Bettina BOTTCHER
08:30 - 17:40 #11509 - Pre-hospital administration of bronchodilators to children under 1 year diagnosed with bronchiolitis: an audit.
Pre-hospital administration of bronchodilators to children under 1 year diagnosed with bronchiolitis: an audit.

Background

Bronchiolitis is a seasonal viral illness characterized by cough, respiratory distress, and variable degrees of wheeze, crepitations and hypoxia. Currently it accounts for 24.2 admissions/1,000 infants and 58.1/1,000 infants of GP consultations in the UK. NICE guidelines (2015) recommend against administering any bronchodilators to children under 1 year with bronchiolitis.

Aim

This audit aimed to identify whether children under 1 year diagnosed with bronchiolitis received bronchodilators in the pre-hospital period and in-hospital within the Emeregency Department. This was compared to the current NICE guidelines.

Methodology

This was a retrospective audit looking at children under 1 year of age presenting to Leicester Royal Infirmary ED between November 2015- March 2016 who were diagnosed with bronchiolitis. 585 children were identified from EDIS database. Data was collected on children arriving via ambulance or self presenting to ED, whether salbutamol or Ipratropium Bromide were administered and whether they were discharged or admitted.

Results

197 children (33.7%) presented via ambulance. Of these 84 (43%) received nebulised Salbutamol pre-hospital. Out of 585 children 114 (19.5%) received pre-hospital salbutamol in the form of inhalers or nebuliser and 14 (2.4%) received pre-hospital Ipratropium Bromide. Interestingly in the Emergency Department 37 (6.3%) of the children received Salbutamol and 159 (27%) received Ipratropium Bromide. 244 (41.2%) were admitted to hospital but this had no relation to the administration of bronchodilators. 

Discussion

This audit highlighted that bronchodilators are still administered to children presenting with bronchiolitis despite the evidence and current guidelines that advise against it. Most practitioners perceived giving medication made them feel like they were 'doing something' as opposed to watch and wait. This has helped us to develop our guidelines in terms with the NICE recommendations and to deliver teaching material to paramedic crew and primary care physicians. 


Habab MEKKI (Leicester, United Kingdom), Gareth LEWIS, Hani GOWAI, Van Eck SHANNON
08:30 - 17:40 #11396 - Pre-hospital management of STEMI according to ERC Guidelines 2015 on the Western Slovakia.
Pre-hospital management of STEMI according to ERC Guidelines 2015 on the Western Slovakia.

Our work retrospectively analyses approach of pre-hospital emergency crews regarding the rapid management of STEMI according to ERC Guidelines 2015 in the two districts of the Slovak republic with population of 139 392 and 735,42 square kilometres (Slovakia's territory spans about 49,000 square kilometres. Total population: 5, 433, 412), region of central Europe near the Bratislava, capital city of the Slovakia. In the intervention area four Ambulance stations (pre–hospital EMS teams: 2 physician - led and 2 paramedics Ambulances). Of the total 10 002 dispatches in the year of 2016 on the districts, 42 were indicated as STEMI. In 2016, the incidence of STEMI for the observed area was 30 patients per 100 000 inhabitants. On average, physician - led crews were dispatched to patients with STEMI once every three weeks, paramedics Ambulances crews once in six months. The retrospective analysis of treatment records in the observed area in patients diagnosed with STEMI reflects 44 parameters (patient history, physical examination, ECG, treatment, time of arrival, transport, time spent on site, ECG – PKI parameter and others) of providing pre-hospital emergency care. By analysing 10 002 records we confirmed observance of professional recommendations ERC Guidelines 2015 STEMI. At the same time, we proved the high quality of provided emergency healthcare. The essential time criterion – interval “ECG - PKI” of 120 minutes was met in 98 % dispatches (with average arrival time of 13 minutes, on-site intervention time of 30 minutes and the duration of transport to cath lab of 25 minutes). Patients were 88% of men aged 42-87 years (average 61 years). Only 46% of patients called emergency line in the first hour. Month with the most frequent occurrence of STEMI was September. However, according to the statistic published by Public Health Care Office in 2011, almost 53% of the Slovak population died from the failure of the cardiovascular system (up to 70% died at home) but only 11% of patients called emergency line within 10 minutes from the onset of symptoms typical for acute myocardial infraction.


Jozef KADLEČÍK, Viliam DOBIÁŠ (Bratislava, Slovakia), Táňa BULÍKOVÁ, Alena DUDEKOVÁ
08:30 - 17:40 #11966 - Preadmission Statin Use and the Outcome of Sepsis- A Population-based Propensity Score Matched Cohort Study.
Preadmission Statin Use and the Outcome of Sepsis- A Population-based Propensity Score Matched Cohort Study.

Background: Randomized controlled trials on post-admission use of statins in ICU patients with sepsis did not show beneficial effects. Whether pre-admission use of statins would confer beneficial effects to sepsis patients has not been well studied.

Methods: We conducted a population-based cohort study on a national health insurance claims database between 1999 and 2011. Patients with sepsis were identified by ICD-9 codes compatible with the sepsis-3 definition. Use of statins was defined as cumulative use of statins for more than 30 days prior to index sepsis admission. We determined the association between statin use and sepsis outcome by multivariate-adjusted Cox proportional hazard models and propensity score (PS) matched analysis.

Results: We identified 52,737 sepsis patients, of which 3,599 were prior statin users. Statin use was associated with a reduced 30-day mortality after multivariable adjustment (HR 0.86, 95% confidence interval, 0.78 – 0.94) and PS matching (HR, 0.88; 95% CI, 0.78-0.99). The beneficial effect could extend to 90 days (HR, 0.90; 95% CI, 0.83 – 0.97). On subgroup analysis, the beneficial effect of statin remain stable regardless of gender and several indication for statin treatment. The beneficial effects of statin were not significant in patients older than 75 years of age, requiring ICU admission, or having shock, or having more than 3 organ dysfunctions. 

Conclusions: In this national cohort study, preadmission statin therapy before sepsis development was associated with a 12% reduction in 30 day mortality when compared to patients who never receive a statin. The beneficial effect tend to be more prominent in less severe patients.


Chien-Chang LEE (Taiwan, Taiwan), Meng-Tse Gabriel LEE, Tzu-Chun HSU
08:30 - 17:40 #9882 - Predicting 30-day mortality in patients with primary intracerebral hemorrhage: Evaluation of the value of ICH and modified New ICH Score.
Predicting 30-day mortality in patients with primary intracerebral hemorrhage: Evaluation of the value of ICH and modified New ICH Score.

Introduction: Different criteria have been proposed for determining the primary intracerebral hemorrhage (ICH) mortality rate. The aim of the present study was to evaluate ICH Score and modified New ICH Score in predicting 30-day mortality in patients with primary ICH.

Materials and Methods: In this prospective cohort study, a total of 107 patients diagnosed with primary ICH were enrolled into the study at an interval of six months (October 2015-March 2016). The Modified new ICH score and ICH score were evaluated. The Modified new ICH was different from the New ICH score since the NIHSS variable was replaced by Modified Rankin Scale (MRS) in the modified score.

Results: A total of 61 patients (57%) died, and 46 patients (43%) survived during the 30 day of hospitalization. ICH≥2 score and Modified  new ICH≥3 score predicted 30-day mortality rate of patients respectively with sensitivity and specificity of 87%, 63% and 88%, 53%.

Conclusion: The current study showed that both ICH score and Modified new ICH score criteria were almost equally effective in determining the mortality of patients with primary ICH, and both criteria have acceptable value in determining the mortality of patients. Therefore, routine assessment ICH score, and Modified new ICH score in patients with ICH in emergency wards is recommend.


Farzad RAHMANI (Tabriz, Islamic Republic of Iran), Alireza ALA, Reza RIKHTEGAR, Aysan FARKHAD RASOOLI, Haniyeh EBRAHIMI BAKHTAVAR, Farnaz RAHMANI
08:30 - 17:40 #11344 - Prediction Of Emergency Department Triage Category And Clinical Presentation On Disposition And Clinical Outcome Of H1N1 Patients.
Prediction Of Emergency Department Triage Category And Clinical Presentation On Disposition And Clinical Outcome Of H1N1 Patients.

Introduction:

 

Since 2009, where the first case of H1N1 influenza infection was reported, a seasonal outbreak in different parts of the world still occur and those patients present to the emergency departments with flu-like symptoms most of the time, but some develop more severe respiratory symptoms and need admission. No available data of how can we predict admission and clinical outcome of such patients on their initial presentation.

 

Objectives:

 

Our aim in this study is to identify predictors of the need for admission and clinical outcome of H1N1 patients in emergency department.

 

Method:

Retrospective chart review of all patients who presented to the emergency department at King Fahad Hospital of the University, Dammam, Saudi Arabia with positive H1N1 flu polymerase chain reaction (PCR) the period between November 2015 and December 2015. We excluded patients with no documented vital signs in the ED visit or no documented triage category in the ED visit. Regression analysis conducted to look for factors that predict The outcome of interest which is the need for of hospital admission or discharge from the emergency department, length of hospital stay or death of patient as a result of this illness.

 

Results:

 

333 positive H1N1 patients identified, of those 80 patients ( 24%) where admitted to the hospital through the emergency department , 4 patients( 1.2%) died during their hospitalization. Triage category 3 was the most frequent with 64.8% , 18% of them got admitted compared to 46.8%. multivariate regression analysis showed that among all vital signs, Tachypnea was found to be a risk for getting admitted in hospital  OR = 1.1; 95% CI : 1.02 – 1.13) (p<0.01). The association between triage category and hospital stay was significant (χ2=6.068 ,p=0.037) where the proportion of triage category 3 was more in the longer hospital stay group compared to category 4. Another significant finding is that patients had dyspnea, they are 4.5 times more likely to have a longer hospital stay (OR = 4.5; 95% CI : 1.2 -17.1) (p=0.025).

 

Conclusion:

 

In H1N1 infected patients, the initial triage category of 3 or less, and increased respiratory rate are found to predict the need for hospital admission where patients with dyspnea symptom have higher chance of longer hospital stay.


Muhammed ALSHAHRANI, Aisha ALSUBAIE, Aisha ALSUBAIE (Riffa, Bahrain), Hind ALSHAMMARI, Nosibah TELMESANI, Maha ALSHAMMARI, Bayader ALKHLIWI, Alaa ALSHAMSY, Reem ALSHAMMARI
08:30 - 17:40 #11557 - Predictive factors for admission to intensive care units of pre hospital acute poisoning.
Predictive factors for admission to intensive care units of pre hospital acute poisoning.

Background: acute poisoning is a common cause of hospitalization in emergency departments and intensive care units. It frequently leads to emergency calls at the regulation call center of the emergency medical service (SAMU). We aim to determine the pre hospital managenent of acute poisoning and the predictive factors for admission to intensive care units.

Methods: a retrospective, descriptive study including patients managed by SMUR medical teams for acute poisoning. Patient's epidemiological and clinical data, pre hospital management as well as patient's orientation were collected.

Results: 174  patients were enrolled between January and December 2016, mean age was 34 ±17 years. Sex ratio was 0.7. Fifteen patients (15%) had psychiatric disease history. Poisoning was unintended in 61% of cases. Carbon monoxide was the most frequent toxic agent (26%), followed by drugs (29%). Benzodiazepine intoxication was the most frequent drug poisoning. Multiple drugs poisoning were found in 28 patients (16%). Three patients (2%) had a cardiac arrest, six patients (3%) were shocked and 10 patients (4%) had a coma. Neurologic symptoms were found in 44% of cases. As for pre hospital management, oxygen was needed in 97 patients (56%), 14 patients (8%) needed intubation and norepinephrine was used for 6 patients (3%). Antidotes were administrated in 45% of cases. Fourteen patients (8%) were admitted directly to a resuscitation and 10 patients (6%) were left alive on site. Patients transferred to an intensive care unit had significantly more electrocardiogram abnormalities and more hemodynamic impairment

Conclusion: eighty-four precent of acute intoxications were referred to an emergency department. Patients transferred directly to an intensive care unit had significantly more electrocardiogram abnormalities and more hemodynamic impairment.


Saida ZELFANI, Wided BAHRIA (tunisie, Tunisia), Syrine KESKES, Hela MANAI, Afef CHAKROUN, Hajer LAKHDHER, Mounir DAGHFOUS
08:30 - 17:40 #11357 - Predictive factors of mortality in severe community-acquired pneumonia.
Predictive factors of mortality in severe community-acquired pneumonia.

BACKGROUND:

Severe community-acquired pneumonia (SCAP) is one of the most common infections seen by clinicians in emergency department and an important cause of morbidity and mortality worldwide. Of hospitalized patients, 10% to 15% require ICU admission; several patients with CAP remains hospitalized in the emergency department.

OBJECTIVE:

To identify factors predicting mortality in  SCAP with data on the first 24h after admission to the intensive care unit (ICU).

METHODS:

Retrospective study over 2-year period that included ICU-admitted patients  with SCAP were studied . Admission pneumonia scores were calculated, and clinical variables were registered during the first 24h.

RESULTS:

A total number of 24 SCAP patients were evaluated. The mean age was 69 + 14 years with a sex ratio of 2. Medical history: hypertension (29,8%), diabetes (37,7%) and tobacco (60,9%). chronic respiratory failure (33,3%), chronic heart failure (12,5%), immunosuppression (32%), patients had cumulated more than three comorbidities in 46 % of cases. The mean PSI score was about 124 +39, class V: 43,5%, the CURB 65 score was greater than or equal to two in 74% of cases, the mean value of APACHE II score was 32,  IGS II score was 69  and SOFA score was 11. All patients were started on antibiotics,25 % of patients had non invasive ventilation (NIV) and 60% had mechanical ventilation (MV),  16 patients died in the intensive care unit. High mortality was frequent in patients with high PSI II score (p=0.005), high IGS II score (p=0.000), high SOFA score (p=0.027), CURB severity score 3-4 (p=0,02). The other prognostic factors related to increased mortality included mechanical ventilation and initial metabolic acidosis.

CONCLUSIONS:

The severe CAP is a frequent condition, which mortality remains considerable. Mortality was correlated with the high prognostic scores of the CAP (PSI and CURB-65) as well as the IGS II and SOFA scores (Prognostic scores in intensive care unit).


Fatma HEBAIEB (Ariana, Tunisia), Eya HNIA, Salah SNOUDA, Moez KADDOUR, Raja FADHEL, Nourreddine DEBBECH, Ameni SGHAIER, Hassen BEN GHEZELA
08:30 - 17:40 #11787 - Predictive factors of recurrent fall: results of a longitudinal study on Iranian Elderly Population.
Predictive factors of recurrent fall: results of a longitudinal study on Iranian Elderly Population.

Introduction:  Fall is a major problem in the elderly, causing injuries, changes in the quality of life and increasing the costs of their life. In this study we tried to find predictive factors resulting recurrent falls in elder patients to check out preventable risk factors.

Materials and Methods: In this longitudinal study, elderly patients over 60 years appeared in the emergency department of to university hospitals were examined and information on the risk factors of falls, were recorded. The cases followed for recurrent falls for six month and relevant data gathered and analyzed.  All questionnaires completed based on direct interview with the patient or a reliable caregiver with complete information about the patient's condition.

Results: Mean age of the participants were 76.7 ± 8.7 years old (n=120). One fourth of the subjects had fallen once during the follow up period (24.2%), and 8.3% experienced more than one falls, while fall did not repeat in half of the elderly people studied (50.7%) (9.2% had been passed away and 7.5% did not finished the follow up which were excluded for analysis). Male sex (OR=0.62), living in personal home (OR=0.64), smoking (never or quitted) (OR=0.78) and living with spouse (OR=0.75) showed preventive risk for fall while having any co morbidity (OR=2.02), falling outside of home (OR=2.58), Imbalance (OR=1.23), slippery floors (OR=1.57), and experiencing major trauma (OR=1.58) would raise the risk of recurrent falls.

Discussion: As emergency physicians usually focus on acute injuries caused by the fall, assessment of functional outcomes and taking action to prevent the fall is rarely performed; hence, it is recommended that a multidisciplinary team evaluate the elder people before discharge and propose required medical and physical environment recommendations to prevent re-falls.


Ehsan MODIRIAN (Tehran, Islamic Republic of Iran), Hamed Basir GHAFOURI, Robab SAHAF, Peyman NAMDAR
08:30 - 17:40 #11934 - Predictive factors of success of intravenous stroke thrombolysis.
Predictive factors of success of intravenous stroke thrombolysis.

Introduction:

Several studies were interested in the evaluation of short and long term outcome (functional, social and mortality) of patient with stroke. IV thrombolysis has improved stroke prognosis.  Many scores based on different factors (comorbidity, stroke severity, clinical and biological finding) has been established to predict the success of this treatment but no score has been recommended by the academic societies.

The aim of our study was to evaluate the predictive factor of thrombolysis success listed on litterature on our population. 

Methods:

Prospective transversal study done in our emergency department from February 2015 to February 2017 based on the analysis of our local register of STROKE. Patient included were divided on 2 groups: group: complete success of thrombolysis and group: relative success, the success of thrombolysis were defined by the decrease of the NIHSS score ≥ 50% at H24. Factor studied were: medical history (HTA, diabetes, stroke, coronaorpathies , dyslipidélimia… ), age, sex, GAD, TAS, NIHSS, ASPECT score at admission.

Results:

The thrombolysis alert were initiated for 187 patient and only 60 patients undergo the treatment , 51,7% were female, medium age were 65,6± 13 years. 56.7% were diabetics and 60% have a history of hypertension. At admission 63,3% have TAS< 160mmhg, GAD at 1,72g/l ±0.93 and NIHSS score were at 8,9± 5. The studied factors were clinical factors (GSC, TAS at admission, NIHSS score) biological factor (GAD at admission, HB) radiological (the ASPECT score) and medical history (diabetes, HTA, FA…). The NIHSS score were lower in the success group ( p=0,02)and there were no other differences in other factors.    

Conclusion:

The NIHSS score is a predictive factor of the thrombolysis success, and we noted a tendency of success on the male population.


Wael CHABAANE, Asma ZORGATI, Lotfi BOUKADIDA, Achref HAJ ALI, Chawki JEBALI, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
08:30 - 17:40 #11109 - Predictive Modeling on Mortality in ED Septic Patients.
Predictive Modeling on Mortality in ED Septic Patients.

Introduction

Sepsis accounts for 14% of mortality in the Emergency Department. An accurate, non-invasive, quantitative means of identifying high-risk septic patients can potentially improve outcomes in the ED setting. Heart rate variability (HRV) analysis has been shown to correlate with mortality in critically ill patients. We aim to predict the 30-day mortality for septic patients presenting to the ED using patient demographics, vital signs and HRV and compare it with the recently introduced quick Sequential Organ Failure Assessment (qSOFA) score.

 

Method

All patients clinically suspected to have sepsis and met at least 2 of the 4 Systemic Inflammatory Response Syndrome (SIRS) criteria were included in this study. Routine triage 6-minute ECG segments were collected, evaluated and processed to obtain HRV variables. The primary endpoint was 30-day mortality. We performed multivariate logistic regression to identify significant predictors and plotted the receiver operating characteristic (ROC) curve to evaluate the importance of these predictors.

 

Results

Of the 368 patients with a clinical suspicion of sepsis, 118 patients did not meet SIRS criteria and 36 patients with non-sinus rhythm or high percentage of artifacts or pre-ventricular complexes in their ECGs were excluded. Of the 214 patients finally included in this study, 51 met the primary endpoint. From our logistic regression model, significant predictors for 30-day mortality were: Age (OR 1.040), respiratory rate (OR 1.124), systolic blood pressure (OR 1.092), SDRR (OR 1.078), RMSSD (OR 0.945), TINN (OR 0.997) and DFA2 (OR 0.085). The AUC for the 30-day mortality was 0.793 (95% CI: 0.727-0.860) compared to that of qSOFA 0.693 (95% CI: 0.611-0.774).

 

Conclusion

Our novel scoring system incorporating HRV parameters can be employed to predict 30-day mortality with a potentially better accuracy than the qSOFA. 


Mas'uud IBNU SAMSUDIN, Mas'uud IBNU SAMSUDIN (Singapore, Singapore), Liu NAN, Liu NAN, Sumanth MADHUSUDAN, Shuling CHONG, Zhi Xiong KOH, Rajesh R, Andrew Fu Wah HO, Marcus Eng Hock ONG, Marcus Eng Hock ONG
08:30 - 17:40 #9854 - Predictive Value of Glasgow Coma Score and Full Outline of Unresponsiveness Score on the Outcome of Multiple Trauma PaArchives of Iranian Medicine , Volume 19, Number 3, March 2016 215 A. Baratloo, M. Shokravi, S. Safari, et al. Introduction E valuating t.
Predictive Value of Glasgow Coma Score and Full Outline of Unresponsiveness Score on the Outcome of Multiple Trauma PaArchives of Iranian Medicine , Volume 19, Number 3, March 2016 215 A. Baratloo, M. Shokravi, S. Safari, et al. Introduction E valuating t.

INTRODUCTION: The Full Outline of Unresponsiveness (FOUR) score was developed to compensate for the limitations of Glasgow coma score (GCS) in recent years. This study aimed to assess the predictive value of GCS and FOUR score on the outcome of multiple trauma patients admitted to the emergency department.
PATIENTS AND METHODS: The present prospective cross-sectional study was conducted on multiple trauma patients admitted to the emergency department. GCS and FOUR scores were evaluated at the time of admission and at the sixth and twelfth hours after admission. Then the receiver operating characteristic (ROC) curve, sensitivity, specificity, as well as positive and negative predictive value of GCS and FOUR score were evaluated to predict patients’ outcome. Patients’ outcome was divided into discharge with and without a medical injury (motor deficit, coma or death).
RESULTS: Finally, 89 patients were studied. Sensitivity and specificity of GCS in predicting adverse outcome (motor deficit, coma or death) were 84.2% and 88.6% at the time of admission, 89.5% and 95.4% at the sixth hour and 89.5% and 91.5% at the twelfth hour, respectively. These values for the FOUR score were 86.9% and 88.4% at the time of admission, 89.5% and 100% at the sixth hour and 89.5% and 94.4% at the twelfth hour, respectively.
CONCLUSION: Findings of this study indicate that the predictive value of FOUR score and GCS on the outcome of multiple trauma patients admitted to the emergency department is similar.


Alireza BARATLOO (Tehran, Islamic Republic of Iran), Sahar MIRBAHA, Alaleh ROOHIPOUR
08:30 - 17:40 #11533 - Predictive value of troponin of patients with non ST elevated myocardial infarction.
Predictive value of troponin of patients with non ST elevated myocardial infarction.

 

Introduction:

The relationship between troponin level and outcomes among patients with non ST elevated myocardial infarction (NSTEMI) is established. The aim of study was to evaluate this parameter in prediction in hospital morbidity of patients with NSTEMI.

Methods:

It was an observational prospective study conducted in an emergency department (ED) during six months (July-December 2015). We excluded patients who had ST elevated myocardial infarction.  We included patients who met criteria of NSTEMI aged more than18 years. The morbidity was evaluated on 30-day events (occurrence of myocardial infarction (MI), hospitalization in cardiac intensive care unit (CICU).

Results:

We enrolled 89 patients. The mean age was 59 years. Sixty eight were males. Sixty seven percent of patients were smokers, 47% had hypertension, 33% diabetes, 13% dyslipidemia and 25% had coronary disease. A depressed ST segment was found in 11.2% of cases, inversed T wave in 10.1%, and left bundle bloc in 5%. The mean troponin of patients admitted to CICU was significantly higner than troponin of others with 2.82 ± 8.45 vs 0.87 ± 2.43 (p˂0.000). The mean troponin of patients with MI was significantly higner than troponin of others with 7.31 ± 8.5 vs 2.26 ± 5.38 (p˂0.00).

Conclusion:

Troponin is an easily available cardiac biomarker for coronary disease. It is a powerful prognosticator to predict adverse cardiovascular outcomes in a NSTEMI population.


Saloua AMRI, Najeh HAJJEM, Imene MEKKI (Tunis, Tunisia), Mohamed Walid MHAJBA
08:30 - 17:40 #11728 - Predictors of major adverse cardiovascular events in patients with acute coronary syndromes without persistent st-segment elevation.
Predictors of major adverse cardiovascular events in patients with acute coronary syndromes without persistent st-segment elevation.

Introduction:

Non-ST-segment elevation acute coronary syndrome (ACS) is a health problem and account for a large proportion of the total number of hospitalizations in emergency department (ED). Despite of the new therapeutic perspectives, the non-ST-segment elevation ACS is a major cause of adverse cardiovascular events. Less is known about the risk factors that predict an increased risk of major adverse cardiovascular events (MACE)  in patients with non-ST-segment elevation ACS.

 

 

Objective: Identify predictive factors of MACE at six-months  in patients with non-ST-segment elevation in ED.

 

Methods: Prospective observational study was conducted over six years. Patients were eligible for inclusion if the diagnosis of non-ST-segment elevation ACS was made (based on anamnestic, clinical, electrocardiographic and biological criteria).  Demographics, co-morbidities, clinical, biological data and in-hospital procedures were collected. The prognosis was evaluated at 6-month on the MACE (Mortality, Recidivism, ulterior myocardial infarction). Multivariate analysis by multiple logistic regressions was performed to identify predictors of MACE.

Results: Inclusion of 390 patients. Mean age = 63 ± 10 years. Sex ratio = 1.5. Comorbidities (%):  hypertension (60), diabetes mellitus (47), coronaropathy (29), hypercholesterolemia (29) and current smoker (31). MACE rate was 30%. In multiple logistic regression, male (odds ratio adjusted = 1.9; p<0.001; 95% confidence interval (1.49-2.6)), history of coronary angioplasty (odds ratio adjusted = 1.9; p=0.01; 95% confidence interval (1.34 -2.8)),  a Thrombolysis in Myocardial Infraction (TIM)I score > 4 (odds ratio adjusted = 1.4; p=0.03; 95% confidence interval (1.04 -2.9)) and a Global Registry of Acute Coronary Events (GRACE) score > 140 (odds ratio adjusted= 2.9; p<0.001; 95% confidence interval (1.2 -3.5)) were independent predictors of MACE at six months.

 

 

Conclusions:

This study shows that male, history of coronary angioplasty, a TIMI score >4, GRACE score > 140 were independently associated with a MACE at 6 months.

 

 

 


Hanen GHAZALI (Ben Arous, Tunisia), Sana TABIB, Anware YAHMADI, Mouna GAMMOUDI, Rihab DIMASSI, Mahbouba CHKIR, Mohamed MGUIDICH, Sami SOUISSI
08:30 - 17:40 #10780 - Predictors of Self-Extubation among Head Injury Patients in Trauma Intensive Care Unit.
Predictors of Self-Extubation among Head Injury Patients in Trauma Intensive Care Unit.

Background: Self-extubation is a most frequent clinical problem associated with mechanical ventilation in trauma intensive care units (TICU). The neurological and physiological status of the patient dictates the type and level of sedation needed to prevent unplanned extubation. 

Aim: We aimed to evaluate the clinical characteristics, nature of sedation, management, outcomes and predisposing factors influencing self-extubation among head injury patients admitted in TICU.

Methods: A retrospective cohort study was conducted to include all intubated head injury patients admitted to TICU of Hamad General Hospital from January 2013 to June 2016. Data were compared and analyzed for patients with planned and self-extubation during weaning from sedation.

Results: A total of 321 head injury patients required mechanical ventilation, of which 39 (12%) had self-extubation and re-intubation was performed in 12 (30.7%) cases. Self-extubated patients were more likely to be older in age, experience agitation (p=0.001), required restraints (p=0.001) and re-intubation (p=0.001) than those with planned extubation. Also, self-extubation is frequently associated with the use of propofol (p=0.002) and tramadol (p=0.001), and these patients had higher Ramsay sedation score (p=0.01), prolonged hospital stay (p=0.03) and were more likely to develop sepsis (p=0.003) as compared to planned extubation.

Conclusions: Self-extubation in head injury patients is significantly associated with agitation, type and level of sedation, prolonged inpatient care and complications. Our study highlighted the importance for assessment of accurate predictors and continuous monitoring of level of sedation  to prevent the incidence of self-extubation.

 

 


Saeed MAHMOOD (Doha, Qatar)
08:30 - 17:40 #11803 - Prehospital management of accidental hypothermia.
Prehospital management of accidental hypothermia.

Introduction:

Accidental hypothermia below 32 ◦C is at risk for cardiac arrest. It is not always isolated and It may complicates an initial medical or traumatic pathology  , his diagnosis is often delayed in many specific circumstances, espatially in the prehospital phase.

Observation:

We reported  the case of a 36-year-old women with a previous history of psycho-affective disorder treated by RIVOTRIL 8mg / day  and DEPAKINE 1.5 g / d, her family called the medical regulation center for an  abrupt alteration of the state of consciousness related to drug poisoning 3 hours ago .After 15 min from the call and in the field, The team of the  emergency medical assistance service (EMAS) found a sleepy women with a glasgow coma score  (GCS = 14/15),a frontal echymosis. The non invasive blood pressure was 90/30 mmHg  without  peripheral signs of shock. Pulse was 70 Bpm and regular. Respiratory and abdominal examination was unremarkable, Bedside testing revealed the blood glucose was 1,2 g/dlt. The temperature was 32 ° C .On the electrocardiogram : we found a sinusal regular rhythm at 70Bpm  with a wave J of osborn. The team of the emergency medical assistance service (EMAS) mobilized carefully the patient and warmed her by blankets, A  500 ml of intrvenous fluid was administred. In cooperation with medical regulation, she was tronsported to an intensive care unit. The final diagnosis was drug intoxication with altered consciousness and falling from one's own height causing meningeal haemorrhage complicated by hypothermia. The evolution was favorable.

Conclusion:

Out-of hospital, the objectives are clear for the team of the emergency medical assistance service (EMAS): Always suspect hypothermia where it can occur, Search for an etiology and respect a circulatory activity preserved.

 

 


Wided BAHRIA (tunisie, Tunisia), Hela MANAI, Saida ZELFANI, Syrine KESKES, Afef CHAKROUN, Slim BEN DLALA, Mounir DAGHFOUS
08:30 - 17:40 #11806 - Prehospital management of cardiac rythm disorder.
Prehospital management of cardiac rythm disorder.

Introduction:

The cardiac rythm disorders are a common cause for intervention in prehospital.Their management falls within a specific and reasoned strategy because of the clinical tolerance and the risk of treatment.

The objective: Describe the management of heart rhythm disorder in the Mobile Emergency and Resuscitation Service.

Methods:

We conducted a prospective study of patients attended by an urgent medical service between 1 January2017 and 28 February 2017 about heart rythm disorder .Data included the diagnosis, the clinical tolerance and treatment were extracted from the medical file.

Results:

We included 31 patients .The sex ratio was 0, 72 .the mean age was 68 ± 15 years. The type of heart rythm disorder  were respectively : bradycardia: (45%),irrugular tachycardia:( 26 %),tachycardia with fine QRS(13%), ventricular tachycardia (6,5%),anothers rythm disorders (6,5%) and ventricular fibrillation (3%). 16 patients had a good clinical tolerance . In (26 %) of cases, the cardiac rythm disorder was associated with a coronary syndrome. The systolic pressure less than 90 mmHg were in (6, 5%) and dyspnea in (10 %).

Conclusion:

 The cardiac rythm disorders are difficult to classify and to treat. Written protocols adapted to the mobile Emergency and Rescucitation Service is necessary to improve care.

 

 

 


Wided BAHRIA (tunisie, Tunisia), Hela MANAI, Saida ZELFANI, Syrine KESKES, Rafika BEN CHIHAOUI, Slim BEN DLALA, Mounir DAGHFOUS
08:30 - 17:40 #10865 - Prehospital triage of patients diagnosed with peptic ulcer: a population-based observational study in the Central Denmark Region.
Prehospital triage of patients diagnosed with peptic ulcer: a population-based observational study in the Central Denmark Region.

Background

Peptic ulcer (perforated peptic ulcer and peptic ulcer bleeding) is a time-critical condition with a high mortality, which is why early diagnostics and treatment are therefore extremely important to reduce the mortality. Inhospital guidelines of these topics are implemented nationwide in Denmark. However, the prehospital stage among patients diagnosed with peptic ulcer has not been investigated.

Purpose

The primary purpose of this study was to investigate the prehospital level of triage, given by the dispatch personnel in the emergency medical communication center, among patients diagnosed with peptic ulcer, and compare this with that of other time-critical conditions with high mortalities. The secondary purpose was to study the mortality among these conditions.

Methods

We studied a group of 8,658 patients making an emergency call in the Central Denmark Region in a three-year period, who were hospitalized

Results

The percentage of level A triage (the most acute level of triage) among patients diagnosed with peptic ulcer was 63.26% (95% CI: 57.12-69.91). Thise was higher among patients diagnosed with respiratory failure; 69.73% (95% CI: 67.85-71.62), stroke; 89.22% (95% CI: 87.67-90.78), trauma; 83.81% (95% CI: 81.86-86.16), cardiac chest pain; 93.22 (95% CI: 91.99-94.45), and cardiac arrest; 92.93% (95% CI: 90.52-93.95). Adjustment for age, sex, total number of hospital contacts in the period, Charlson Comorbidity Index Score, and time of day of call did not change the results considerably. The percentage of level E triage (the least acute level of triage) among patients diagnosed with peptic ulcer was 6.47% (95% CI: 3.28-9.65). This was lower among all the compared conditions. The 30-day mortality among patients diagnosed with peptic ulcer was 7.83% (95% CI: 4.52-11.13). This was only exceeded by that seen in respiratory failure, stroke, and cardiac arrest.

Discussion

The results indicate that patients diagnosed with peptic ulcer do not receive the right rapid prehospital response needed. This suggests that these patients are undertriage at the level of dispatch. The main objective of the emergency medical communication center is dispatch the right level of triage in order to keep the degree of undertriage at the lowest level. Future studies should therefore explore the actual content of the conversation between patients diagnosed with peptic ulcer and the dispatch personnel to identify risk factors for undertriage. 

Conclusion

Patients diagnosed with peptic ulcer is less likely to receive the most acute prehospital level of triage and more likely to receive the least acute prehospital level of triage compared to other severe, time-critical conditions. 


Stud. Med. Kasper BONNESEN (Aarhus N, Denmark), M.d. Kristian FRIESGAARD, Professor, Dr. Med. Lone NIKOLAJSEN
08:30 - 17:40 #11849 - Preparedness and cooperation of emergency services in CBRN incidents involving children - proposing solutions in Poland.
Preparedness and cooperation of emergency services in CBRN incidents involving children - proposing solutions in Poland.

Study/ Objectives:

Proposed solutions of support and medical care for children in CBRN incidents is an activity that aims to increase the knowledge and skills of Emergency Medical Services and Fire Department rescuers and hospital’s clinic and non-clinic personel during such events. In the face of current threats, this is a very important task for every country, including Poland, to be prepared to rescue the pediatric population.

Background:

Recent years have shown that incidents involving weapons of mass destruction are becoming more and more dangerous. These hazards can affect all communities and different populations. A large group in developed countries (including Poland) are children. If CBRN happens, the pediatric population is particularly vulnerable to these types of attacks. Non-medical and medical rescue should be different from that for adults. This is due to the unique needs of pediatric patients and the capabilities of the rescue system (knowledge and skills of rescuers, service and infrastructure cooperation).

Methods:

We have analyzed the procedures, recommendations, infrastructure, personnel and equipment that relate to the provision of assistance to pediatric patients in CBRN events. On the basis of the best solutions of the various emergency services (Emergency Medical System, The State Fire Department, Polish Armed Forces), we have proposed a new model of assistance dedicated to pediatric patients. The proposal of solutions has been tested during the simulation of CBRN events involving children.

Results:

The developed response model of the rescue system in Poland for CBRN incidents involving pediatric patients includes the unique needs of pediatric patients (anatomical, physiological, psychological, social), lifeguards, decontamination, transport, service collaboration and communication both with the child and between the emergency services. Verification in practice has shown the effectiveness of our model of action.

Conclusions:

It is very important for each country to develop guidelines for helping children in CBRN incidents. This makes it possible to increase the chances of saving as many pediatric victims as possible. Thanks to our CBRN pediatric rescue model, it will be easier in Poland to cooperate with services in such situations. This will help reach the goal to save many children's lives.


Katarzyna DLUGOSZ (Kraków, Poland), Arkadiusz TRZOS
08:30 - 17:40 #11282 - Preseptal cellulitis: An eye emergency.
Preseptal cellulitis: An eye emergency.

INTRODUCTION: Pre- and postseptal sellulitis, although both of an infectious etiology and involving periocular tissues, are very different entities with different morbidities. Preseptal sellulitis (periorbital cellulitis) is an infection of the eyelids and periocular tissues that is anterior to the orbital septum. In this study we present to a case of preseptal cellulitis in ED.
CASE: 66- year-old female patient admitted to the ED with complaints of swelling, redness and pain on the right side of face and jaw. She had comorbid diseases including COPD, DM, CHF hypertension and hypothyroidism. In history she suffered swelling on the neck, ear pain and swallowing a week. In addition to these edema expanding to right side of face, redness and pain had developed a day. CBC samples revealed WBC:17,500, CRP:14,9 mg/dl. As radiological evaluation orbital CT showed density on the right preseptal area (Preseptal cellulitis). The ultrasonography of submental area was normal. After first treatment she was interned to infectious diseases clinic with prediagnosed preseptal sellulitis.
CONCLUSION: Orbital and periorbital infections exist in a spectrum of increasing severity: preseptal (periorbital), postseptal (orbital) cellulitis, orbital abscess, and cavernous sinus thrombosis, from least to most severe. Preseptal cellulitis is generally benign and may be treated in the outpatient setting. CT scan differentiates the two conditions. Differentiation of preseptal and postseptal cellulitis is essential. A misdiagnosis can result in significiant neurologic disability and death.


Mehmet UNALDI (Istanbul, Turkey), Soner ISIK, Didem AY, Kurtulus AÇIKSARI, Onur INCEALTIN, Vehbi OZAYDIN, Hatice ERYIGIT
08:30 - 17:40 #11673 - Preventable mortality in patients at low risk of death requiring prehospital ambulance care: structured judgment case note review.
Preventable mortality in patients at low risk of death requiring prehospital ambulance care: structured judgment case note review.

Background

Reviewing patient records for quality of care can help to identify deaths that could have been avoided. Any failures identified can inform measures to improve the quality of patient care. Mortality reviews are increasingly being conducted in hospitals but the evidence for their validity in pre-hospital ambulance settings is limited. We aimed to review the records for avoidable deaths relating to care provided by emergency ambulance services.

Methods

Ethical approval was sought and gained to link ambulance call, dispatch and clinical data with hospital and mortality data from patients attended by one UK ambulance service for records over a period of 6 months in 2015. The anonymised dataset was used for analysis. Patients who died within 3 days of the initial ambulance call were selected for case review. Cases were stratified according to age group (age 0-2, 3-10, 11-20, 21-30, 31-40, 41-50, 51-60, 61-70, 71-80, 81-90, and 91-120 years), dispatch code classification and urgency (Red1 - Green4) to ensure maximum variation. The number of calls within each group, and the number of deaths (within 3 days of a call) within each group was calculated. The death rate for each group was determined and groups were sorted by this rate (lowest first), selecting 6 patients from those with the lowest mortality rate in each group. A structured judgement case note review method with 5 reviewers (GP, nurse, 2 paramedics and a medically qualified health service manager) was used to assess in detail anonymised patient records for quality of care and avoidable mortality relating to the care provided by one ambulance trust.

Results

In total, 153 records were selected from 150037 where the patient had been subsequently transported to hospital or died. These represented patients from different age, condition and urgency groups with the lowest risk of death. Most patients selected for review (81%; 124/153) were transported to hospital. At initial assessment 10% (16/153) of cases showed strong or probable evidence of avoidability and 2% (3/153) possible evidence of avoidability based on lack of care provision according to current national UK guidance. Evidence of avoidability was more likely in those patients that were not transported to hospital (38%; 11/29). A further assessment was made in light of the diagnosis of death which reduced the number of cases showing strong or probably evidence of avoidability to 7% (11/153).

Conclusion

Structured judgment cases reviews can be used to assess avoidable mortality in prehospital ambulance care and to inform deficiencies and improvements in care processes. This requires access to ambulance records linked to hospital and mortality data to ensure that accurate assessments are made in light of the final diagnosis and cause of death. 


Aloysius Niroshan SIRIWARDENA, Joseph AKANUWE, Annabel CRUM, Joanne COSTER, Richard JACQUES, Janette TURNER (Sheffield, United Kingdom)
08:30 - 17:40 #11356 - Preventive Effect of Motorcycle Helmet on Mortality and Intracranial Injury in Severe Trauma.
Preventive Effect of Motorcycle Helmet on Mortality and Intracranial Injury in Severe Trauma.

Introduction

Traumatic brain injury following motorcycle crash is related to severe mortality, functional disability and high healthcare costs. Higher speed of motorcycle might cause greater potential for injury. Helmet is the crucial protective equipment for motorcyclists. However studies comparing the interaction effects of helmets and speed of motorcycle are limited. This study aimed to evaluate the protective effects of motorcycle helmet on clinical outcomes and compare the effects across high- and low-speed motorcycle crash.

 

Methods

This is a cross-sectional observational study using a nationwide, prospective registry of severe trauma patients treated by EMS providers in Korea. The study population was all severe trauma patients who injured by a motorcycle crash between from January 2013 and December 2013. The primary outcome of the study was intracranial injury. The secondary outcome was in-hospital mortality and the tertiary outcome was intensive care unit admission. Multivariable logistic regression analysis was performed to calculate adjusted odds ratios of helmet use for the study outcomes. The interaction model with an interaction term between helmet use and speed of motorcycle was performed to determine variability of the preventive effect on helmet use according to different speed of motorcycle.

 

Results

Among 495 eligible patients, 105 (21.2%) patients wore helmets. 256 (51.7%) patients had intracranial injury. The proportion of high-speed of motorcycle crash was higher in patients with intracranial injury (47.3% vs. 26.8%, p <0.01). The motorcycle helmeted group was less likely to have intracranial injury (adjusted ORs 0.53 [0.33–0.84]) and be admitted to ICU (adjusted ORs 0.47 [0.29-0.75]).There was a significant preventive effect of motorcycle helmet on intracranial injury when the speed was less than 30 km/h (adjusted ORs 0.50 [0.27–0.91]).

 

Conclusion

Wearing helmets among severe trauma patients injured from motorcycle crashes has preventive effects on intracranial injury and ICU admission. The preventive effects were significant in low-speed motorcycle crashes. 


Sola KIM (Hwaseong, Republic of Korea), Yu Jin KIM, Jeong Ho PARK, Young Sun RO, So Yeon Joyce KONG
08:30 - 17:40 #11067 - Primary brain tumour- atypical Emergency Department(ED) presentations.
Primary brain tumour- atypical Emergency Department(ED) presentations.

Introduction

We use a case series of 3 patients with primary brain tumour to illustrate atypical presentations to the ED.

Cases

Case 1- 46 year old healthy male presented fall from a bicycle. With detailed history-taking there was no reason for the accident, and he described 5 days history of headache, nausea and vomiting so a CT was requested. CT brain showed 6.5x3.7 primary mass lesion in the right parietal lobe with intralesional haemorrhage and surrounding oedema with significant mass effect with left midline shift of 11.2cm.The patient was treated with Dexamethasone and he was admitted on neurosurgical team.

Case 2- 46 year old healthy male presented with a 1 week history of behavior change, referred to ED as a likely new onset psychiatric presentation. More detailed history-taking revealed urinary incontinence and headache. CT brain showed a genu mass lesion in keeping with lymphoma most likely, with differential butterfly glioma.  A later MRI brain confirmed to be  Primary CNS lymphoma.The patient was treated with Dexamethasone and his  case was discussed in MDT meeting in Neurooncology team .

Case 3- 54 year old lady known ethanol misuse, presented with a fall secondary to ethanol intoxication with head injury and loss of consciousness.A CT brain was performed as part of Head Injury protocol which  showed an incidental finding 5.5 mass in the right frontal lobe crossing the midline in the right parietal and left temporal lobes. MRI brain showed high grade glial series tumour.The patient was admitted on Medical team where she had CT-CAp which was negative and she was treated with Dexamethasone. her case was also discussed in MDT meeting in Neurooncology.

Discussion

Brain tumours classically present to ED with seizures, or sometimes with headache as primary presenting complaint. It is important to remember more subtle presentations such as an apparent accident (collapse beforehand), behavioral change, new-onset incontinence. We also must have in mind that the findings can be incidental, like in the 3rdcase in which the CT brain was performed as part of the head injury protocol.

Discussion with senior ED doctors gleaned advice to always ask questions such as “has anything else strange happened lately”, in order to pick up subtle neurological symptoms that may point to space-occupying lesions.


Dr Nicoleta CRETU (Leicester, United Kingdom), Blake SYKES, Ffion DAVIES
08:30 - 17:40 #11947 - Profile of the affections of the elderly Tunisian patients in the medical emergency deparetment of military hospital of Tunis.
Profile of the affections of the elderly Tunisian patients in the medical emergency deparetment of military hospital of Tunis.

Introduction: Ageing is characterized by a decrease in functional reserves, unmasked during acute situations in patients often exhibiting comorbidities. Emergency units are one of the main access roads to the hospital for the elderly. Their management in emergencies is difficult because of varied motives for consultation, lack of information, semiological atypia and a risk connected to polymedication.

Purpose:Describe the profile of the affections of Tunisian elderly patient in the medical emergencies.

Methods: In this prospective and descriptive study conducted in the emergency department, we included all patients aged more than 65 years admitted to emergency medical unit during January 2017. We excluded patients consulting for trauma or for a surgical pathology.

Results: During the study period, 100 patients were included, 53 % were masculin. Average age was 74,8 years (extremes 65-90), the sex-ratio was 1,1. 40 % of our patients were dependent on a third person. 80 % of the patients had medical histories and 68 % of them had more than three pathological antecedent. The motives for consultation was respiratory signs (47 %), chest pain (26 %), neurological signs (12 %), digestive and urinary signs (9%) and no specific symptoms (6 %). The main found affections were pleuropulmonary disease (31 %), cardiovascular disease (26 %), infectious (22 %), neurological (11 %), metabolic (9 %) and abdominal (4 %). severe clinical presentation were noted in 5 % of cases. the average length of stay was 2,2 days (extremes 1-6 days) and 74 % of the patients had a length of stay of 72 hours. The rate of death was 3 %, whereas 78 % of the patients had a favorable evolution and 13 % were transferred in specialized department.  

conclusion: the affections of elderly subject are numerous and complex. In Tunisia, they are dominated by pleuropulmonary and cardiovascular diseases. a geriatric reasoning will permit the differentiation between aging, chronic and acute pathology that should be pursued because profitable in terms of diagnosis and treatment.

 

    


Mansouri SALWA (Tunis, Tunisia), Hamami RIM, Ben Lassoued MAHDI, Lamine KHALED
08:30 - 17:40 #11568 - PROGNOSTIC FACTORS AND STRATEGIES OF FLOW MANAGEMENT IN SEPIS CASES.
PROGNOSTIC FACTORS AND STRATEGIES OF FLOW MANAGEMENT IN SEPIS CASES.

INTRODUCTION. Sepsis is a clinical condition of disseminated and uncontrolled inflammation associated with an infectious outbreak.The organization of patient flow through the health system, ensuring ICU beds is critical.OBJECTIVES. Evaluate the association of the prioritization of Vacancies in ICU with the mortality,morbidity and hospital stay time of the patients;the strategy of prioritizing vacancies in the access of patients in severe sepsis or septic shock to ICU beds;the strategy of prioritization of vacancies in the delay to access of patients in severe sepsis or septic shock to ICU beds and the strategy of prioritization of vacancies in the mortality of patients in severe sepsis or septic shock to ICU beds;The Quick SOFA prognostic index in patients with severe sepsis or septic shock admitted to U.E.-HCFMRP-USP.Methodology:This is a retrospective cohort based on administrative data obtained from January 01,2010 to December 31,2016.We used Student t tests, Analysis of Variance or non-parametric equivalents, chi-square or Fisher´s exact test and Receiver Operating Curves for univariate analysis.Multivariate logistic regression with binary or categorical outcome and multivariate Poisson regression as appropriate for the multivariate analysis.A p< 0.05 or the exclusion of the unit from the confidence interval signaled statistical significance.Results:Patients who received higher priority for ICU access(priority 1-5826;62,5%)were younger (55;12-100-p< 0,01),had less comorbidities(Charlson 0,3583;61,5%,p< 0,01) and less severity(Quick SOFA 0,2170;37,2%-p< 0,01;SOFA< 10%-1782;0,5%-p< 0,01).They were admitted in greater proportion (2097;35,9%-p< 0,01) and had faster access to ICU (1081;52,5%-p< 0,01),presenting lower mortality (1853;31,8%- p< 0,01).The odds ratio to receive priority 1,higher value of the Charlson class OR 0,53; 0,49-0,57, the Quick SOFA (Severity)-OR 0,45;0,43-0,48 and the presence of Sepsis condition-OR 0,20-0,17;0,23 were independently associated with a lower chance of being classified as priority 1.Sepsis was more associated to lower chance of receiving priority 1(0,2; IC 95%-0,17;0,23).It persisted as an independent factor for total in-hospital mortality(2,7;IC 95%- 2,32;3,17) and for the mortality of patients admitted to the ICU(2,38;IC 95%-1,82;3,11).The prioritization of vacancies facilitated the access of the septic patients to the ICU.There was no delay in ICU admission for septic patients who received priority 1 (0,43; IC 95%-0,35;0,53).The Quick SOFA prognostic index had low accuracy in patients with severe sepsis or septic shock admitted to U.E.-HCFMRP-USP (AUROC=0,5646,IC95%-0,52991;0,59930-p< 0,001).Conclusions:Sepsis presented a high mortality even when admission to the ICU was guaranteed. Flow management strategies were effective in securing access in ICU.REFERENCE:Neves FF, Pazin-Filho A.Management of resources in intensive care:application Of an information system for row organization.2016;7(2):730-41


Hudson PIRES (Uberaba, Brazil), Fábio NEVES, Antonio PAZIN-FILHO
08:30 - 17:40 #11343 - Prognostic Factors of Pneumococcal Meningitis in Emergency Resuscitation.
Prognostic Factors of Pneumococcal Meningitis in Emergency Resuscitation.

 Introduction: Streptococcus pneumoniae is the most commonly encountered germ in adult bacterial meningitis. The prognosis of this condition remains very severe despite recent advances in the development of new antibiotics and in symptomatic management in intensive care of the most severe patients.

Purpose: The objective of this study was to analyze the epidemiological, clinical, paraclinical, therapeutic and evolutionary profile of this condition and to determine the predictive factors of death.

 Materials and methods: This work is a prospective study carried out in the emergency department of the ERU Ibn Rochd Hospital in Casablanca. It includes 37 adult patients admitted between January 2012 and September 2016 for confirmed pneumococcal bacterial meningitis. Inclusion criteria: patients over 15 years of age with severe pneumococcal meningitis (PNP). Patients under 15 years of age were excluded. All other bacterial meningitis. Meningitis has clinical features in favor of meningitis with PNO, but the germ has not been isolated in the CSF study. Epidemiological, clinical, biological, radiological and evolutionary characteristics were analyzed, according to a global descriptive study and a univariate analytical study aiming at assessing the association between two variables, a variable is considered statistically significant for a value p≤ 0.05.

 Results This study showed an average age of 42.97 ± 14.99 years with a male predominance, as well as the presence of risk factors in 97.29% of patients. Febrile meningeal syndrome (75.67%) and febrile consciousness disorders (62.16%) were the main symptomatic symptoms. Patients with pneumococcus susceptible to penicillin were isolated in the majority of cases (94.59%). A neutrophilic leukocytosis was observed in 89.18% of cases, and brain imaging showed abnormalities in (72.97%) of cases The therapeutic strategy was based on antibiotic therapy in all patients as well as resuscitation measures including intubation assisted ventilation in 75.67% of cases. The outcome was fatal in 45.94% of cases and 3 patients (8.10%) had sequelae after discharge. In our study the predictive factors of death are: advanced age,  A low GCS, hospitalization time> 48 hours, cerebral edema at the scanner, septic shock and the use of mechanical ventilation.

Conclusion: According to this work, mortality remains high, possibly due either to diagnostic delay or to the wide and unjustified use of the cerebral scan before lumbar puncture, Administration of the antibiotic


Mezgui OTHMAN (CASABLANCA, Morocco), Khaleq KHALED, Benseghir BASSAM
08:30 - 17:40 #11150 - Prognostic value of acute kidney injury after carbon monoxide intoxication based on the Kidney Disease Improving Global Outcomes (KDIGO) criteria.
Prognostic value of acute kidney injury after carbon monoxide intoxication based on the Kidney Disease Improving Global Outcomes (KDIGO) criteria.

Background: Acute kidney injury (AKI) occurs after carbon monoxide (CO) poisoning, but limited data were available. This study aimed to evaluate the incidence and prognostic value of the AKI in patients with acute CO poisoning

Methods: We conducted a retrospective cohort study using prospective registry of CO poisoning between January 2010 and December 2014. AKI was defined and classified according to the Kidney Disease Improving Global Outcomes (KDIGO) criteria, and multivariate logistic regression analysis was used to determine the association between AKI and poor outcome. Poor outcome was as persistent neurological complications and 28-day mortality.

Results: A total of 661 patients were finally included in this study, and AKI occurred in 57 (8.6%), 44 (77.2%) of whom were classified as KDOGO stage 1; 7 (12.3%) as KDIGO 2, and 6 (10.5%) as KDIGO 3.  Five of 57 patients (8.8%) in AKI groupincluding the 3 patients treated with continuous renal replacement therapy, did not recover from AKI. The development of AKI in CO poisoning was independently associated with poor outcome (odds ratio, 39.71; 95% confidence interval, 4.03–390.99; P = 0.002).

Conclusions: AKI occurred in about one tenth of patients with CO poisoning, and most patients in KDIGO AKI stage 3 (5/6, 83.3%) had impaired renal function during hospitalization. The presence of AKI was associated with poor outcome.


Soo-Han CHO (Seoul, Republic of Korea), Youn-Jung KIM, Won Young KIM
08:30 - 17:40 #11376 - Prognostic value of distortion of the terminal portion of the QRS complex in ST-segment elevation myocardial infarction.
Prognostic value of distortion of the terminal portion of the QRS complex in ST-segment elevation myocardial infarction.

Background:

The distortion of terminal portion of the QRS complex (DisQRS) is defined as positive T waves in leads with ST-segment elevation (ST+) and emergence of the J point at > 0.5 of the R wave in leads with a qR configuration or disappearance of the S wave in leads with an Rs configuration in two or more consecutive leads. It was independently associated with increased hospital mortality in patients undergoing reperfusion therapy for ST-segment elevation myocardial infarction (STEMI).

The purpose of this study was to analyze admission electrocardiogram in patients of STEMI based on DisQRS and its correlations to: occurrence of complications, successful thrombolysis and early mortality.

 

Methods:

This prospective study was enrolled   over a period of 36 months. To be included in this analysis, patients with STEMI and admitted within 12 h from the onset of symptoms with positive T waves in leads demonstrating ST+ and lack of right or left complete branch block or ventricular pacing. Qualifying patients were divided into two subgroups (DisQRS+ and DisQRS-) based on the presence or absence of DisQRS on the admission electrocardiogram.

 

Results:

A total of 264 STEMI patients were included. Mean age was 57 ± 12 years. The pain-to-door time was less than 3 hours in 63.8% of cases.  DisQRS+ was observed in 50.8% of patients. Thrombolysis represented the coronary reperfusion approach in 86% of STEMI. The successful thrombolysis rate was 70%. The occurrence of cardiac arrest was observed in 7.2% of patients mainly in the form of a threatening cardiac dysrhythmias. The death in the vital emergency room was 2.3%.

Multivariable analysis confirmed that DisQRS was independently associated with the threatening cardiac dysrhythmias (adjusted odds ratio=2.096; p=0.035) and the occurrence of cardiac arrest (adjusted odds ratio=2.245; p=0.014).

 

Discussions:

The distortion of the terminal portion of the QRS complex appears as a simple electrocardiographic tool for the initial assessment of the severity of the ST-segment elevation myocardial infarction. It represents an independent predictor factor of the threatening cardiac dysrhythmias and the occurrence of cardiac arrest.


Sarra JOUINI (Tunis, Tunisia), Mohamed MEZGHANNI, Rym HAMED, Hana HEDHLI, Mohamed KILANI, Abir WAHABI, Hela BEN TURKIA, Chokri HAMOUDA
08:30 - 17:40 #11336 - Prognostic value of leuco-glycemic index in st segment elevation myocardial infarction.
Prognostic value of leuco-glycemic index in st segment elevation myocardial infarction.

Introduction

Several biological markers are used to predict poor outcomes in st segment elevation myocardial infarction (STEMI). Glycemia and white blood count are known as predictive factors of major cardiac events occurrence in STEMI. What about the composite score: leuco-glycemic index (LGI) ?

The aim of our study was to evaluate the prognosis value of leuco-glycemic index in patients admitted to the emergency department (ED) with STEMI.

Methods

Prospective observational study over eight years. Inclusion of patients admitted to the ED with STEMI. Retrospective analysis of LGI (LGI = glycemia (mg/dl) * white blood count (elements/mm3) / 1000). The final endpoints were major cardiac events (MCE) (severe heart rhythm disorder, cardiogenic shock, acute heart failure, cardiac arrest) during the first 24 hours and death at six months.

Results

The study evaluated 410 patients of 811 patients. Mean age = 59 +/- 12 years. Men  n(%) : 342 (83).  Mean LGI =  2553 +/- 1763. Thrombolysis  n(%) : 291 (71).

The LGI area under the ROC curve for the MCE and death at 6 months were respectively: 0,681 ; p<0,001 ; IC 95% [0.595-0.767] et 0.712 ; p=0.002 ; IC 95% [0.581-0.843].

The best prognostic cut-off value for LGI was 2100. In univariate analysis,  LGI > 2100 was associated to  2.2 threshold risk of MCE (p=0.001 ; IC 95% [1.386-3.528] and 4.4 risk of death (p=0.005 ; IC 95% [1.497-12.839]).

Conclusions

LGI is a good prognostic score. It can predict poor outcomes during the acute period and after six months. 


Hanène GHAZALI (Ben Arous, Tunisia), Ines CHERMITI, Anware YAHMADI, Hedia GNENA, Morsi ELLOUZ, Ihsane HENANE, Saoussen CHIBOUB, Sami SOUISSI
08:30 - 17:40 #10909 - Prolonged cardiopulmonary resuscitation and thrombolytic therapy for sudden cardiac arrest in patient with acute pulmonary embolism.
Prolonged cardiopulmonary resuscitation and thrombolytic therapy for sudden cardiac arrest in patient with acute pulmonary embolism.

Background:


Acute pulmonary embolism (PE) is one of non-cardiac causes of cardiac arrest (CA), having a poor prognosis, with reported mortality ranging from 65% to 95%. Bedside diagnosis of acute PE in the Emergency Department can be challenging, especially in a cardiac arrest setting. Echocardiography could have a great clinical impact in patients with cardiac arrest, who can receive specific treatments for CA resulting from PE, including administration of fibrinolytics, surgical embolectomy and percutaneous mechanical thrombectomy.

Case:


A 46-year-old healthy man came to the hospital because of retrosternal chest pain and palpitations. The electrocardiogram showed ventricular tachycardia and pharmacological cardioversion was attempted with amiodarone without reestablishing sinus rhythm. Due to progressive haemodynamic instability, electrical cardioversion was attempted. Immediately after that, he developed CA with pulseless electrical activity, requiring advanced cardiopulmonary life support with mechanical chest compression device. In order to diagnose the cause of CA, we performed a focused echocardiography that revealed marked right ventricular dilatation and abnormal interventricular septal wall motion on parasternal short-axis view. With the diagnosis of PE, alteplase infusion (100 mg) was begun immediately. Return of spontaneous circulation was achieved. The total duration of cardiopulmonary resuscitation (CPR) was 60 min.

After the patient was stabilized, a CT scan demonstrated extensive bilateral pulmonary embolism in most segmental arteries. He was admitted to the intensive care unit. Upon reinterrogation, we discovered that he had been diagnosed a week before of meniscal tear root, and was in bed-rest prior to surgery. 6 weeks later the patient was discharged from the hospital on low molecular weight heparin, with no neurologic deficits.

Conclusions


- Because of unspecific clinical presentation of PE, it is important to obtain information about predisposing factors that may support the diagnosis, such as previous PE or deep vein thrombosis, surgery or immobilisation, active cancer, oral contraceptive use or long-distance flights.

- Echocardiography is an additional diagnostic tool to identify PE if it can be performed without interrupting chest compression, or during rhythm check.

- CA due to PE commonly presents as pulseless electrical activity. Ongoing CPR is not a contraindication of fibrinolysis. Once a fibrinolytic drug is administered, CPR has to continue for at least 60-90 min before terminating resuscitation attempts. Survival with good neurological outcome have been reported in cases requiring over 100 min of CPR.


Ángel CABALLERO (Barcelona, Spain), Marta MAGALDI, Antonio LÓPEZ, Mireia CHANZÁ, José María GÓMEZ, Jaume FONTANALS
08:30 - 17:40 #11268 - Proteinuria and edema.
Proteinuria and edema.

Female 38 years allergic to ampicillin, clinical history of hypothyroidism in treatment with levothyroxine and a family history  of diabetes mellitus with secondary chronic kidney disease in her mother.

Came to the emergency department  for 1 month with generalized edema predominant in the lower extremities, asthenia, oligoaunuria, presence of foam in the urine, arthralgia and hematuria 
that the patient initially confused with metrorrhagia despite having had normal menstruation weeks before. At the beginning of the clinic she consulted by similar clinic; an urine test was performed and showed  total protein>400; red cells>100, white cells>100. At that time, was treated as a urinary infection.

On emergency presents: Tª: 35ºC; FC: 60lpm; TA:155/68mmHg. Normocolored and normohydrated. Conscious and oriented, no neurological deficit. Rhythmic cardiac auscultation;
respiratory auscultation with preserved vesicular murmur; and normal abdominal examination. Bilateral edema in lower extremities.

An electrocardiogram and a chest-x-ray were performed, without alterations. Venous gasometry showed a metabolc alkalosis. Blood test: hemoglobin: 9,25; PT:12,6%; urea:88; creatinine:1,35mg/dl; total protein:50,9; albumin:22,7g/l;Na: 136; K:5,9. Urine test: proteins>400; red cells15-30/ field and leukocytes 30-50/field.

She was admited to nephrology where started with furosemide and ciprofloxacin. Control blood test were performed with renal function worsening. A renal biopsy was performed showing a  Lupus nephritis;  an inmunological study was performed too.

Treatment with corticoid bolus , mycophenolate 1g every 12 hours and a first dose of rituximab were started and creatinine levels improved with persistent proteinuria.  At discharge diagnoses were: systemic lupus erythematous, lupic glomerulonephrytis and Secondary nephrotic syndrome. And she continued in treatment with mycophenolate, prednisone and rituximab.

After discharge, she continues to undergo nephrology controls with proteinuria still in the nephrotic range despite treatment months later.

Edema is a frequent cause of emergency consultations, and when linked with proteinuria, as is the case of our patient, we must always include the nephrotic syndrome in our differential diagnosis, since up to 30 percent of adults with this syndrome have associated Systemic diseases such as diabetes mellitus, amyloidosis or systemic lupus erythematosus, diseases whose diagnosis can go undetected without a correct orientation in the emergency room.


Maria Esperanza RIUTORT THOMAS, Carme PUJOL, German FERMÍN, Karina VALDEZ, Maria Del Carmen RODRIGUEZ, Julio OLSEN, Claudina REVOL (Palma de Mallorca, Spain)
08:30 - 17:40 #11482 - PULMONARY CRYPTOCOCCUS INFECTION PRESENTED WITH MULTIPLE NODULES OF RIGHT LUNG.
PULMONARY CRYPTOCOCCUS INFECTION PRESENTED WITH MULTIPLE NODULES OF RIGHT LUNG.

Introduction: Pulmonary cryptococcosis is an opportunity infection commonly occurred in the immunocompromised patients. However pulmonary cryptococcosis in the immunocompetent was reported up to 35% and this case tend to show confined and localized radiologic findings than in immunocompromised patient.

 

Case report: Our patient, a 68 year-old woman, housewife, has past history of rheumatic arthritis on Prednisolone and Methotrexate treatment. She presented to our emergency department (ED) with complaint of intermittent epigastric discomfort, headache and chills for two days. She denied traumatic injury or symptoms of urinary/respiratory tract infection. The pain was over epigastric area without radiation or migration. The headache was over the bilateral temporal area.

There are coarse breathing sound over the right lung without obvious heart murmur in the initial physical examination, otherwise was unremarkable. Electrocardiogram show normal sinus rhythm with right bundle branch block. The laboratory data found no leukocytosis or elevated cardiac enzyme. The laboratory data revealed mild elevated C-reactive protein (0.31 mg/dl).

Chest radiograph (figure 1) showed multiple nodules over the right lung field. Chest computed tomography (figure 2-A, 2-B) showed multi-focal consolidations and/or nodular lesions of the right lung.

Because of the tentative diagnosis of pulmonary infection or suspicious malignancy, she was admitted to our Division of Chest for antibiotics treatment.

After admission, CSF analysis was performed according to the neurologist’s advice due to poor medication response of the intermittent headache. CSF analysis found positive Cryptococcus antigen(1:512) and follow up blood exam also found positive Cryptococcus antigen(1:1024). Under the impression of cryptococcus meningitis and pulmonary cryptococcosis, amphotericin B was prescribed for the infection. Her headache improved after treatment and discharge 34 days after admission. The follow up chest radiograph show below(Figure 3).

 

Discussion: Disseminated cryptococcosis is a systemic mycosis that predominantly affects immunocompromised patients. The risk factors for this infection include HIV/acquired immune deficiency syndrome, connective tissue disease, diabetes mellitus, chronic kidney disease, liver cirrhosis, long-term steroid use, exogenous immunosuppression, and solid-organ transplant. C. neoformans and C. gattii are the main causative agents of cryptococcosis.

Usually, the inhalation of Cryptococcus causes focal pneumonitis, and the infection is generally detected as single or multiple pulmonary nodules. Disseminated cryptococcosis most frequently infects the lung and central nervous system but can also infect the skin, prostate, and bones.

The diagnostic tools that can be used to detect cryptococcosis include histology, fungal cultures, the serum cryptococcal antigen test, and radiography.


Chang JER-RUEY (CHIAYI, Taiwan)
08:30 - 17:40 #10937 - Pyometra presented with sepsis and abdominal pain in the elderly.
Pyometra presented with sepsis and abdominal pain in the elderly.

Introduction
Pyometra, a condition of pus accumulation in the uterine cavity, is an uncommon gynecologic problem, which is mainly seen in postmenopausal women. Pyometra is commonly idiopathic, and the sufferers are usually older and debilitated. Only a few patients with pyometra present gynecologic symptoms such as vaginal discharge or vaginal bleeding.
Most patients only display non-specific symptoms such as abdominal pain, fever, and leukocytosis. For these patients, the correct diagnosis is usually not made until operation for the pyometra. For those cases with non-specific symptoms, abdominal computed tomography (CT) is the usual imaging study of choice. Reported here is a case of pyometra with initial presentation of fever and abdominal pain.

Case report
A 91-year-old female with a past medical history of diabetes mellitus presented with fever and abdominal pain 12 hours prior to admission. Patient denied vaginal discharge or vaginal bleeding recently. Initial vital signs were temperature 38.7℃, pulse rate 121/min, respiratory rate 22/min, blood pressure 99/59 mmHg, room air SpO2 96%. Physical examination revealed suprapubic tenderness without peritoneal signs. Chest X-ray revealed no obvious subphrenic free air or widening mediastinum. ECG revealed sinus tachycardia. Laboratory data revealed WBC: 24320/μL, Seg: 86.2%, creatinine: 1.42 mg/dl, lactate: 60 mg/dL, CRP: 13.82 mg/dL, glucose 203 mg/dL.
Abdominal CT with/without contrast was arranged for survey of infectious focus. The abdominal CT result revealed pyometra with air-containing abscess formation 7.1 x 8.2 cm in size. No intrauterine device was detected inside the uterus. Gynecologist was consulted and operation (dilatation and drainage) was arranged. In both blood and pus cultures Enterococcus faecalis was isolated. Pathology report revealed negative for malignancy.

Discussion
CT plays a role in evaluating patients with abdominal pain or a fever of unknown origin. Familiarity with the appearance of pyometra in a CT is helpful for early diagnosis and the reduction of mortality. Pyometra appears on the CT as a fluid-distended uterus, which should be carefully differentiated from a pelvic abscess. Pyometra is an uncommon condition, but the incidence of associated malignancy is considerable, and the risk of spontaneous perforation is higher than previously thought. Dilatation and drainage is the treatment of choice, and regular monitoring after initial treatment is warranted to detect persistent and recurrent disease.


Jiun-Jia CHEN (Taichung City, Taiwan)
08:30 - 17:40 #11930 - Pyomyositis in sternocleidomastoid and sternohyod muscles.
Pyomyositis in sternocleidomastoid and sternohyod muscles.

Case report

A 50-year-old man presented to our Department with no previous medical history, who is dedicated to gardening. The patient reports a 1-week history of neck pain in the left lateral area and in the last 3 days appears a progressive tumor in the left supraclavicular area, associating redness, febrile sensation and chills. No associated respiratory symptoms or dysphagia. No recent trauma or previous infection. Before admission, he was treated with anti-inflammatory therapy without benefit.
A physical examination showed fever, pain on palpation and swelling over the left supraclavicular area. Neurological, respiratory, and cardiovascular examinations were normal.
Laboratory tests documented an increased C-reactive protein concentration, and he had leukocytosis and neutrophilia. A computed tomography (CT) was performed, showing inflammation of his sternocleidomastoid and sternohyod muscles. For this reason, intravenous antibiotic treatment was started, and drainage was necessary. Owing to a positive blood culture with staphylococo aureus, cloxacillin was added to his therapy.
During his hospitalization, our patient’s clinical condition progressively improved. The length of therapy was 4 weeks. A few months later our patient was symptom free.

Discussion

Pyomyositis is an acute bacterial infection of skeletal muscle that results in localized abscess formation. This infection was thought to be endemic to tropical countries, however, pyomyositis is increasingly recognized in temperate climates and is frequently associated with an immunosuppressive condition. Intensive exercise and local trauma have been suggested as risk factors, but only a third of patients had evidence of these risk factors. Pyomosytis occurring infrequently and to a lesser extent in the neck muscles. Clinical manifestations are varied so it's very important to make an early and correct diagnosis. Diagnosis can be delayed because the affected muscle is deeply situated and local signs are not apparent, that can result in increased morbidity and a significant mortality rate.
Imaging is the best modality to define the features and the extent of muscle infection. The CT is the most sensitive technique and currently accessible for the diagnosis of Pyomyositis.
If the disease is recognized early, antibiotic therapy alone is usually sufficient. Abscess formation, however, requires appropriate drainage.
The most common pathogen is Staphylococcus aureus, so initial therapy should include a broad-spectrum agent with adequate coverage, and therapy should subsequently be modified depending on results of blood culture. The therapy is initially administered intravenously and generally lasts 3–4 weeks.
Our patient was not immune-compromised, the only risk factor to consider is the potential muscular stress as well as the risk of skin lesions in relation to his profession. Also, he lived in a temperate climate, so that confirming that pyomyositis is not an exclusive pathology of tropical countries.


Maria Del Carmen RODRIGUEZ CASIMIRO, Diana DIZ GONZALEZ (Malaga, Spain), Maria Del Carmen CASIMIRO VAZQUEZ, Aurora CABO LOPEZ, Angelica CANAS BARRANCO
08:30 - 17:40 #11028 - Quality Improvement Project : 3-in-1 Block For The Patients With Hip Fractures in OLOL Drogheda Emergency Department.
Quality Improvement Project : 3-in-1 Block For The Patients With Hip Fractures in OLOL Drogheda Emergency Department.

TITLE : Quality Improvement Project : 3-in-1 Block For The Patients With Hip Fractures in  Emergency Department 

INTRODUCTION Hip fractures are a common presentation to emergency departments and are known to have high morbidity and mortality. Patients with this injury are commonly elderly and a large percentage have significant co-morbidities and are often taking numerous medications. As per the first round of audit of management of hip fracture in our emergency dept, there was poor compliance to guidelines for management of hip fractures with a prolonged time to analgesia in this patient population. 54% of the audit sample waited 4 hours or longer before they received analgesia between Oct 2015-Feb 2016. OLOL Drogheda has large patient volumes presenting to the ED with transfers from Navan, Cavan and Dundalk. 

Literature confirms that 3 in 1 nerve block has superior analgesic effect than IV opioids used alone and is safer with lesser side effects compared to opioids alone.  We carried out a quality improvement project to ensure efficiency and proficiency in our ED medical staff for performance of nerve blockage.

METHODS We carried out an online survey among Emergency Medicine and Orthopaedic NCHDs to measure their anatomical and practical knowledge and confidence about giving 3-in-1 nerve block to the patients with a hip fracture. Survey results have shown that there were limited knowledge about pre-procedure controls such as monitoring and obtaining informed consent, and lack of confidence among the NCHDs. Following that, we arranged a classroom teaching about relevant clinical anatomy, basic ultrasound techniques, hands-on imaging on a live model and practical sessions on a rooster flesh. Hard copies of up-to-date literature summaries, local anaesthetic calculation formulas, local anaesthetic systemic toxicity protocols were given to the NCHDs and placed in resuscitation room and tagged with ultrasound device.

RESULTS We have noticed improvement in offering analgesia to patients presenting with suspected hip fracture to ED and increased confidence among NCHDs to perform nerve block in patients with confirmed hip fracture.

CONCLUSION  We are performing the second round of the audit after educating the medical and nursing staff about compliance with guidelines for management of patients with hip fracture. We are introducing a local protocol with a multidisciplinary agreement for same highlighting the effective analgesia achieved with the 3 in 1 nerve block and aim to ensure that the NCHDs in the ED and orthopaedics are trained efficiently for the 3 in 1 block.


Canberk MESELI, Farah MUSTAFA (Drogheda, Ireland), Niall O'CONNOR, Conor KELLY
08:30 - 17:40 #10173 - Quality in Emergency Medicine:Performing Extended FAST (eFAST) ultrasound in trauma bay in a regional district Hospital of Greece.12 Months Experience.
Quality in Emergency Medicine:Performing Extended FAST (eFAST) ultrasound in trauma bay in a regional district Hospital of Greece.12 Months Experience.

Introduction: Focus assessment ultrasound in trauma (FAST) is the basilar  procedure on trauma triage. Performing the Extended FAST (e-FAST)  is the evolution in the ultrasound diagnosis on trauma  that permits diagnosis in the two major cavities of the body ,abdomen and chest, allows for the examination of both lungs by adding bilateral anterior thoracic sonography to the FAST exam and is ruling the surgical definitive care decision.

Objective: To determine the necessity to perform eFAST in our Institution in Trauma Bay and evaluating  data thru Radiological Board  Diagnosis .

Methods/Materials : Retrospective study of consecutive trauma patients presenting  in ED undergone thru eFAST diagnosis  in 12 months (2016) recording  demographic  data , patern of injury, injury cause, ISS, outcome and diagnosis.

Results: All patients were managed thru ATLS/APLS/DSTC algorithm from certified surgeon. Eligible were with eFAST diagnosis  87 trauma patients (♂62/♀25),Median age 46,4 (4-84) mostly reported and registered with minor trauma (ISS<16).The patter of injury caused was most from motor vehicle accidents (MCA) 33,03% (n=29) following ground falls in 20,68 (n=18) .Dismissed in 48,27% (n=42),admitted 31,03% (n=27) and transferred 13,72% (n=12) ,thru EMS, with severe trauma (ISS>16) to the proper Trauma Service mostly with Trauma Brain Injuries under mechanical ventilation . Diagnosis ,from board Radiologists, in  all patients for the classical Fast ultrasound and in 35 % (n=30) computerized tomography. One false negative eFAST case confirmed.

Conclusions: In our district Hospital with no Trauma Team service performing eFAST in Trauma bay is beneficiary in life time keeping for the definitive surgical care . In ED with an experienced operator  permits diagnosis and  decisions, even in multiple MCA, rapidly to define the decisive surgical  care.

References:

1.  American Institute of Ultrasound in Medicine, American College of Emergency Physicians. AIUM practice guideline for the performance of the focused assessment with sonography for trauma (FAST) examination. J Ultrasound Med. 2014 Nov. 33 (11):2047-56. [Medline].

2.  Montoya J, Stawicki SP, Evans DC, Bahner DP, Sparks S, Sharpe RP, et al. From FAST to E-FAST: an overview of the evolution of ultrasound-based traumatic injury assessment. Eur J Trauma Emerg Surg. 2015 Mar 14. [Medline].

3.  Soult MC, Weireter LJ, Britt RC, Collins JN, Novosel TJ, Reed SF, et al. Can routine trauma bay chest x-ray be bypassed with an extended focused assessment with sonography for trauma examination?. Am Surg. 2015 Apr. 81 (4):336-40. [Medline].

4. Wilkerson RG, Stone MB. Sensitivity of bedside ultrasound and supine anteroposterior chest radiographs for the identification of pneumothorax after blunt trauma.Acad Emer Med. 2010 Jan;17(1):11-7.


5.Alrajhi K, Woo MY, Vaillancourt C. Test Characteristics of Ultrasonography for the Detection of Pneumothorax: A Systematic Review and Meta-analysis. Chest. 2012 Mar;141(3):703-8.


Vasileios KALDIS (ATHENS, Greece), Theodoros ZAROKOSTAS, Ioannis SKLIRIS, Vasiliki VASILAKOPOULOY, Christos PASPALIARIS, Ioannis MITRAKOS, Ioannis POYLOS, Demetrios GIANNAKOPOYLOS
08:30 - 17:40 #11680 - Quality of the dispatcher-assisted bystander resuscitation from emergency call center.
Quality of the dispatcher-assisted bystander resuscitation from emergency call center.

Introduction and objective

The aim of the study was to evaluate the capacity of untrained bystanders to follow correctly the instructions given by an Emergency Medical Service Coordination Center, in order to identify an OHCA, follow a CPR sequence, perform CPR maneuvers and evaluate times and quality.

Methods

The sample included 34 volunteer university students with no previous experience in Basic Life Support (BLS). In an isolated room, the compliance with instructions for identifying cardiac arrest (CA) and the quality of the CPR maneuvers for 3 minutes on a Laerdal skill reporter manikin were assessed. The instructions were given by EMSCC (FPUS 061 in Galicia) following the European Resuscitation Council (ERC) recommendations.

Results

The following of instructions was 5.9% for evaluation of consciousness, 17.6% for breathing; 92.1% managed to carry out thoracic compressions, with a mean depth of 23.4 mm and a mean frequency of 87 compressions per minute. The time from the call until the start of compressions was, on average, 132 seconds.

Conclusions

Despite the dispatcher-assisted bystander resuscitation is a recommendation to improve the untrained bystander CPR, in our study, according to the quality parameters of the international reccommendations on life support, the CPR provided was less efective than a CPR performed by a trained bystanders.


Miguel FREIRE-TELLADO, Antonio IGLESIAS VAZQUEZ (SANTIAGO, Spain), Marta FERNANDEZ-LOPEZ, Pilar PAVON-PRIETO, Ruben NAVARRO-PATON, Daniel VAZQUEZ-LOPEZ, Ivan LOPEZ, Olga DOSIL-DIAZ
08:30 - 17:40 #11818 - Quantitative Electroencephalogram (QEEG) as a diagnostic and prognostic tool of Traumatic Brain Injury patients. A prospective study on Romanian Emergency department patients.
Quantitative Electroencephalogram (QEEG) as a diagnostic and prognostic tool of Traumatic Brain Injury patients. A prospective study on Romanian Emergency department patients.

BACKGROUND AND AIM

Traumatic Brain Injury (TBI) is defined as an alteration of brain function, or other evidence of brain pathology, caused by an external force. TBI is considered the “silent epidemic”, as problems resulting from TBI are often not immediately visible and TBI patients are not very vociferous.

The most frequently used severity markers of TBI are: computer tomography (CT), Glasgow Coma Scale (GCS) on admission, the duration of coma state or the one of post-traumatic amnesia, yet these have a poor sensibility as prognostic factors of the patient’s long term evolution.

The EEG is a physiologic measure of the cerebral function that has been used to assess coma and prognosticate survival and global outcome after TBI. Numerous studies have shown that EEG can identify functional cerebral anomalies prior to these being visible as structural lesions on CT scan in patients with minor TBI.

The aim of this study is the early identification of moderate to severe TBI patients (GCS 8-12), to improve the long-term outcome.

METHOD

The study is designed as a prospective observational one and 60 moderate-severe TBI patients will be included in the study during their first emergency department visit. An QEEG assessment (32-channel EEG caps) will be performed on day 10, 30 and 90 from the traumatic event. The recordings are made with the patient having their eyes opened and closed and performing cognitive tasks. EEG recordings will be taken during the recognition phase while the participants will be asked to determine whether the images were old or new. 10 seconds frames will be evaluated through QEEG.

The study is designed for adult patients with no previous history of neurological or psychiatric conditions and moderate-severe TBI, without any other associated trauma.

 

RESULTS

Cluj-Napoca Emergency Department assesses over 60.000 patients per year. The study protocol is undergoing approval by the local Ethics Committee and will be implemented starting with November 2017.

 

DISCUSSION

This study will evaluate the role of quantitative electroencephalogram as early biomarkers of cognitive impairment in patients with moderate-severe TBI. QEEG, a useful tool for assessing the severity of moderate-severe TBI, could enable a fast-tracking protocol for this group of patients, to minimize the impact on the quality of life and the social and economic burden of this condition.


Lacan SORIN MIHAI, Golea ADELA (Cluj Napoca, Romania), Muresan EUGENIA MARIA
08:30 - 17:40 #11398 - Quick sequential (sepsis-related) organ failure assessment (qSOFA) score in infected patients in emegencies department.
Quick sequential (sepsis-related) organ failure assessment (qSOFA) score in infected patients in emegencies department.

Objective:
The study aim was to assess the diagnostic and prognosic value of  quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) in infected patients in emergencies.
Patients and methods:
Descriptive retrospective study including old patients, aged more than 18 years, who were admitted to the emergency department with proven infection during twenty three months (january 2015 and november 2016).
Results:
Ninety six patients were included. The average age was 69 years with 48 patients were males. Twenty nine percent of patients had hypertension (HTA), 24% active cancer, 16% diabetes and 34 % had more than three past history. Thirty two percent of patients had positive qSOFA score on admission (≥ 2 criteria). The average length of stay was 9 days. The occurrence of complications in patients with positive qSOFA score at admission was 58.1% versus 16.9% in patients with negative qSOFA score (p=0.000). Thirty two percent of patients with positive qSOFA score were admitted  to intensive care unit (ICU) versus 6% with negative qSOFA score (p˂ 0.01).
Conclusion:
The positivity of qSOFA  score at admission may be considered as a significant prognostic factor in infected patients presenting to the emergency department.


Saloua AMRI, Imene MEKKI (Tunis, Tunisia), Mohamed EL AHMED, Hafida MACHET, Alexandre CREPPY
08:30 - 17:40 #11571 - Radiation and increasing use of computer tomography in Emergency Department.
Radiation and increasing use of computer tomography in Emergency Department.

Background

Computer tomography (CT) is widely used in all developed countries. The number of CT examinations in Emergency Departments (EDs) is increasing continuously. CT examination is based on ionizing radiation, which may cause well known health hazards. Because of its potential negative effects, we should try to minimize radiation exposure needed in CT imaging. Through development of CT scanners (from traditional reconstruction to iterative construction), the reduction of radiation dose has become possible. On the other hand, the increasing use of CT leads to higher cumulative doses of ionizing radiation in subjects visiting EDs. One of the most common time-limited diagnostic challenges in the ED is a suspected acute ischemic stroke (AIS). Its rapid diagnosis and initiation of intravenous thrombolytic therapy is of most importance. To obtain the diagnosis of AIS, a cranial CT taken without delay is essential. Also patients with suspected pulmonary embolism, acute abdomen and major trauma are often undergoing CT examinations.

Patients and methods

Kanta-Häme Central Hospital has a catchment population of 175 000. The ED is an active clinic of a secondary hospital taking care of emergency cases like ischemic stroke, heart problems, intoxications, acute abdomen and traumas. This is a single-centre study to reveal the evolving role of CT in the ED. Our aim was to reveal the numbers of emergent CT studies over last years, to quantify the mean CT examination dependent radiation dose, and finally to analyse the total radiation of patients studied in the ED. In this preliminary study we calculated the mean number of monthly CT scans of six consecutive months at the beginning and at the end of the study period. Then we multiplied it by the mean dose of CT examinations taken in the ED. Radiation dose is expressed as milli-Sievert (mSv).

Results

From January 2015 to March 2017, the mean number of monthly CT examinations increased from 424 to 546, which indicates a 28.7% increase. This is equivalent of 1.2 % monthly increase of CT scans. The mean radiation dose was 6.63 mSv. So, without any change of CT scanners i.e. by using examinations with traditional reconstruction, the increase of CT examinations had increased the total radiation dose/month in the ED from 2811.1 mSv to 3620.0 mSv. This increase of 808.9 mSV in monthly CT examinations is equivalent with the background radiation of about 270 years for our ED patients/month. We are continuing this study not only by using radiation doses given by CT scanners, but we also aim to measure direct radiation of two different generation CT scanners by using phantom models.


Jussi VATANEN (Hämeenlinna, Finland), Ville HÄLLBERG, Ari PALOMÄKI
08:30 - 17:40 #10994 - Rapid diagnosis protocol of acute dyspnea in over 65 years old patients presenting to the Emergency Department.
Rapid diagnosis protocol of acute dyspnea in over 65 years old patients presenting to the Emergency Department.

Introduction: Diagnosis of acute onset dyspnea is difficult, particularly in the elderly. Our study’s main objective was to assess the superiority in terms of time and accuracy of a rapid diagnostic protocol (near patient care – NPC®) based on a pleuro-pulmonary echography (PPE) and point of care (POC) arterial blood gases (ABG) (epoc® System - AlereTM) in patients over 65 years old admitted for acute dyspnea in an emergency department (ED).

 

Material and method: Monocentric observational trial of routine care in patients >65 with acute dyspnoea over 8 randomly assigned 5-day periods (1 December 2015 until 31 March 2016). This protocol was implemented on ED admission with a focused clinical exam, a chest X-ray, Boston and Geneva scores, ABG and PPE. The overall time to diagnosis of NPC® was compared to the standard one from a previous patient cohort. Accuracy of diagnosis was evaluated at the end of the hospital stay and compared between the two diagnostic methods.

 

Results: 81 patients were included. The average time to diagnosis was 79,119 min (± 48,11) for NPC® while it was 224,153 min (±131,90) for the standard method. The average difference of diagnostic time between the two methods was 145 min (p < 0,001) and statistically significant. Accuracy of diagnosis with the NPC® method was 93,8% (IC 95[86,2-98%]).

 

Conclusion: This rapid diagnostic protocol (NPC®) relied on a global assessment (clinical biological and imaging) and lead to accurate diagnosis significantly faster. Patients over 65 years old presenting to ED for acute dyspnea could benefit earlier from accurately targeted management.


Laurence BOIRON (Marseille), Soreya GOUMIDI, Thibaut MARKARIAN, Alexie GARDON
08:30 - 17:40 #11584 - Rapid sequence intubation (RSI) in an UK emergency department.
Rapid sequence intubation (RSI) in an UK emergency department.

Introduction:

The provision of safe and rapid anaesthesia in the Emergency Department is vital in a select group of critically unwell patients. A 2011 census showed that 0.12% (1/8000) attendances required rapid sequence induction. (1) 80% of RSI’s in this census were undertaken by anaesthetists and 20% by EM physicians.

The Royal College of Emergency Physicians (RCEM) has recognised the importance of EM physicians being able to provide emergency anaesthesia, making RSI a core skill for higher trainees.(2)

Anaesthesia in the Emergency Department at Addenbrookes is unique in that approximately 90% of intubations are undertaken by emergency physicians. Hence the onus is on us to ensure the care we deliver is both safe and excellent. 

Methadology: 

Data collection from 2005 - 2012 using the Royal College of Emergency Medicine airway audit tool

Results:


100% Successful Intubation with no surgical airway. 78.82% first pass success rate (85.2% since 2008). Complication rate of 18.3% (number of patient with at least one complication). 87.5% of the Intubation were performed by emergency physicians. 82% of the intubations were performed by the emrgency medicne registrar and 11% were performed by the mergency medicne Consultant. 

Conclusion:


7 years of data from a large emergency department shows that rapid sequence intubation can be safely performed by emergency physicians. The success and complication rates are in keeping with the internationally published data. There were no surgical airway performed. 

References:


1 Rapid sequence induction of anaesthesia in UK emergency departments: a national census. Jonathan Benger et al Med J 2011;28:217-220 doi:10.1136/emj.2009.085423

2 RCEM Curriculum: http://www.rcem.ac.uk/Training-Exams/Curriculum 


David LEVERTON, Vazeer AHMED, Wayne KARK (Cambridge , United Kingdom), Matthew PEREIRA, Maria SMITH, Adrian BOYLE
08:30 - 17:40 #11458 - Rare CNS Manifestation Of Cytomegalovirus In Immunocompromised Patient: A Case Report.
Rare CNS Manifestation Of Cytomegalovirus In Immunocompromised Patient: A Case Report.

Hi

HERE BY SENDING AN ABSTRACT FOR e POSTER ON  RARE CNS MANIFESTATION OF CYTOMEGALOVIRUS IN IMMUNOCOMPROMISED PATIENT: A CASE REPORT


Ashraf PUNNORATH (Al Khor, Qatar)
08:30 - 17:40 #11681 - Realization of the electrocardiogram by the nursing auxiliary: Is a transfer of skills possible?
Realization of the electrocardiogram by the nursing auxiliary: Is a transfer of skills possible?

Context: Performing an electrocardiagram (ECG) is a task for the Emergency nurse (EN).That is done several times daily at Emergency Departments, and requires specific training. At 11% of the Emergency Departments in France, that is done by the nursing auxiliary (NA). Our study aims at evaluating the transfer of skills from EN to NA in realizing ECG. For that we determined their training level, whether they had differing practices, and whether a short training course would enable them to be more efficient in positioning the electrodes.

Methods and material: We conducted a prospective study of pre-test/post-test type from June to September 2016 at the Emergency Department (ED) for adults at the Chartres Hospital in France. We studied the positioning of precordial electrodes by EN and NA before and after a training course. That short training course emphasized recommendations on the practical realization of an ECG.

Results: A questionnaire evaluating the degree of training was filled by 24 NA and 44 EN. For 92% of them they had either no previous training or a training dating from 11 years ago on average (2-31). We studied their positioning of electrodes (in 116 ECG with 12 derivations in 10 ECG with 18 derivations) prior to new training; in 87% of cases an NA was operating, and EN in 13% of the cases. The mean distance between the correct position and the actual one was 41 mm (0-200) (in fact 33mm for the standard derivations and 50mm for the right-hand and posterior derivations).
The distance between the correct position and the actual one was significantly greater with women (V3, V4, V5), overweight patients (V1 to V6),
and with a NA operating compared to an EN (V2,V5) (p<0.05);
We studied 154 ECG (126 ECG with 12 derivations et 28 ECG with 18 derivations) after a training course. 78% were realized by an NA and 22% by an EN.
The mean distance between the correct position and the actual one was 16mm (0-70). After that training those distances were not significantly different for AS operating compared to EN (except for V8, less well positioned by EN's).

Conclusion: A short training course for electrode positioning induces a better practice for both NA and EN's in performing ECG. Under adequate and regular training, ECG can be realized by NA. However, that transfer of skills must be controlled by a precise protocol.


Alexandre HENNIART, Eric REVUE (Paris)
08:30 - 17:40 #10593 - Recommended Sites for Reliable Monitoring of Oxygen Saturation via Pulse Oximeter.
Recommended Sites for Reliable Monitoring of Oxygen Saturation via Pulse Oximeter.

Introduction

Measurement of arterial oxygen saturation using pulse oximeter is a non-invasive technique that is widely accepted as a standard practice. There is an increased demand of continuous and instantaneous monitoring of arterial oxygenation at hospital and out of hospital settings. This study focuses on identifying the best site for placement of pulse oximeter probe to measure oxygen saturation. The study also aims to compare the accuracy and reliability of portable finger pulse oximeters with fixed gain hospital based pulse oximeter. 

Methodology

Twenty-three healthy male volunteers aged 20 to 40 years old were recruited in this study. Cold pressor test was done to stimulate vasoactivity and 460 measurements of SpO2 level were obtained throughout the study. The results were analyzed  with ANOVA with p < 0.05 was considered to be significant. Bland-Altman plot was used to determine the bias and the internal consistency of each measurement sites of SpO2 level throughout the test was identified via Cronbach-Alpha (α).

Results

The highest average SpO2 mean value was measured from the earlobe using ear sensor.  Thus, differences of the mean SpO2 level measured from different sites were statistically significant (F(10,253) = 2.077, p <0.05). Based on post-hoc test, the significant differences were between the level estimated at the ear with both right and left index and little fingers. Cold pressor test also revealed good internal consistency with no significant difference of means for SpO2 level at different time point using the ear sensor (F(3,92) = 0.829, p > 0.05; α = 0.89), right thumb (F(3,92) = 0.42, p > 0.05; α = 0.86), right middle finger (F(3,92) = 0.137, p > 0.05; α = 0.96) and right ring finger (F(3,92) = 0.016, p >0.05; α = 0.97). Comparison between the hospital based pulse oximeter with the portable finger pulse oximeter via Bland-Altman plot analyses indicated a low bias with 0.85% for the thumb (95% CI: 0.18 to 1.52), 1.01% for right middle finger (95% CI: 0.43 to 1.59) and 1.07% for right ring finger (95% CI: 0.50 to 1.65).

Discussion & conclusion

The differences or bias between measurements at different sites in this study may not be clinically significant. However, the result from this study provides evidence for standardization of probe placement sites in order to gain reliable SpO2 level via pulse oximeter. The best site for cutaneous oxygen saturation measurement is at the earlobe using ear sensor. Portable finger pulse oximeter that is readily available in the market is a reliable tool for SpO2 estimation. However, accuracy of the measurement as compared to the standard (hospital based pulse oximeter) is highly dependent on the site of measurement. The right thumb, middle and ring fingers are the recommended sites. These sites are less affected by low temperature. Therefore, standardization of placement of finger sensors is strongly suggested either in hospital or out of hospital settings.

 

 

 


Juliana NORSHAM (Kuala Lumpur, Malaysia), Sahar AZMANI, Huda AINUL, Idrose ALZAMANI, Amirfaiz SYED, Iqmaliza NUR, Abdul Rahman HAYATI
08:30 - 17:40 #10920 - Recurrent abdominal pain and usefulness of bedside ultrasound in the emergency department.
Recurrent abdominal pain and usefulness of bedside ultrasound in the emergency department.

Purpose: Abdominal pain is a common symptom in emergency room (ER), covering 10% of the assists. The delay in diagnosis and treatment adversely affects the patient's prognosis.Transabdominal ultrasonography is most commonly used to obtain images of hepatobiliary, urogenital, and pelvic structures. However, improvements in ultrasound technology and increasing familiarity with ultrasonographic findings in a variety of gastrointestinal disorders, as Crohn's disease (CD), are broadening its applications, and it is an aspect to be considered by emergency physicians (EP) in patients with recurrent abdominal pain. We present a case of CD, diagnosed at ER, through the use of ultrasound scanning by EP.

Material & Methods: a patient with abdominal pain, with a final diagnosis of an CD

Results: 36 year old male, was admitted to the ER for the third time by abdominal pain. Emergency analytical were unremarkable, as in the preceding cases. Because of the pain the emergency physician underwent an ultrasound scan observing area terminal ileum same transmural thickening with luminal narrowing and decreased peristalsis, involvement of the mesenteric lymph nodes and multiple underlying fat, suspecting CD. We entered the patient performing CT abdomen and ileo-colonoscopy confirmed the diagnosis.

Conclusion: Bedside ultrasound of the patient by the EP could be an useful tool in cases with abdominial pain whose clinical data and laboratory are unclear. Suspicion of CD, the sensitivity of ultrasound is nearly 90%, especially if ileal location, as in the case presented; being the specific data and the transmural segment thickening, and the presence of fistulae or abscesses. Stenosis exists ultrasound specificity is greater than 95%. Due to its great advantages such as low cost, accessibility, not irradiated and non-invasive ultrasound should be considered in the diagnosis and monitoring of all CD, therefore EP must be trained to diagnose sonographically acute complications of this disease.


Margarita ALGABA MONTES (Sevilla, Spain), Alberto Ángel OVIEDO GARCÍA, Francisco LUQUE SÁNCHEZ
08:30 - 17:40 #11643 - Recurrent Deep Venous Thrombosis while on Therapeutic Low Molecular Weight Heparin.
Recurrent Deep Venous Thrombosis while on Therapeutic Low Molecular Weight Heparin.

Background

Patients who suffer venous thromboembolisms (VTEs) while on anticoagulation is a poorly understood cohort, whose management guidelines are based on scant evidence. The incidence of VTE reccurence among patients on anticoagulation is roughly 5-7%. CHEST Guidelines on Antithrombotic Therapy for VTE advise if a patient suffers a VTE on oral anticoagulants they should be switched to LMWH. If a patient suffers a VTE on LMWH then the dose should be increased by 20-25%. This is based on Grade 2C evidence, citing only one retrospective cohort study.

This case also involves the use of an emergency physician performed ultrasound (EPPU). It is an underutilised modality as it is time consuming, requires a skilled senior physician and radiologist confirmation as a follow up. However, a meta-analysis of EPPU with over 2000 patients found 96.1% sensitivity and 96.8% specificity.

Case Report

We present the case of a 44 year old woman who presented on a Sunday with acute onset left leg pain and swelling. She had tenderness to the posterior of her left leg, 4cm leg circumference difference and tenderness along her left femoral vein. At the time she was already prescribed and compliant to tinzaparin 18000iu.

Her past history included a left sided illeofemoral DVT in 2004, an IVC thrombosis and a right sided popliteal DVT in 2008. She then commenced lifelong anticoagulation with warfarin and received an IVC filter and right sided internal and common iliac stents. In 2015 her stents clotted and she was commenced on lifelong therapeutic tinzaparin. Her thrombophilia screen under haematology was negative for any underlying condition.

Access to U/S over the weekend is extremely limited, usually patients are discharged on LMWH and an U/S is done during the week as an outpatient. In this case the suspicion of a proximal DVT must be established, as 50% develop a PE and the patient is already high risk. 

EPPU was preformed, which demonstrated non-compressibility of the left common iliac vein. This was instrumental in acquiring a departmental ultrasound which confirmed a proximal DVT.

This patient was admitted and a CT Peripheral Venogram found complete thrombosis of the intrahepatic IVC, both distal renal veins and left internal and external iliac veins. These findings warranted an urgent catheter thrombolysis and IVC filter removal. 

Recommendations

This unusual case highlights the value of an objective physical exam, bearing in mind up to 5-7% of patients on anticoagulation for VTEs can develop a recurrence. Current guidelines recommend dose escalation in the event of proven recurrence, therefore investigation is justified. In this patient’s case, urgent thrombolysis was warranted. EPPU, despite its shortcomings, has a high sensitivity and specificity and can be instrumental in the expedited care of select cases.


Amir ALSAFFAR (Galway, Ireland), Mustafa MEHMOOD
08:30 - 17:40 #11645 - Recurrent Deep Venous Thrombosis while on Therapeutic Low Molecular Weight Heparin.
Recurrent Deep Venous Thrombosis while on Therapeutic Low Molecular Weight Heparin.

Background

Patients who suffer venous thromboembolisms (VTEs) while on anticoagulation is a poorly understood cohort, whose management guidelines are based on scant evidence. The incidence of VTE reccurence among patients on anticoagulation is roughly 5-7%. CHEST Guidelines on Antithrombotic Therapy for VTE advise if a patient suffers a VTE on oral anticoagulants they should be switched to LMWH. If a patient suffers a VTE on LMWH then the dose should be increased by 20-25%. This is based on Grade 2C evidence, citing only one retrospective cohort study.

This case also involves the use of an emergency physician performed ultrasound (EPPU). It is an underutilised modality as it is time consuming, requires a skilled senior physician and radiologist confirmation as a follow up. However, a meta-analysis of EPPU with over 2000 patients found 96.1% sensitivity and 96.8% specificity.

Case Report

We present the case of a 44 year old woman who presented on a Sunday with acute onset left leg pain and swelling. She had tenderness to the posterior of her left leg, 4cm leg circumference difference and tenderness along her left femoral vein. At the time she was already prescribed and compliant to tinzaparin 18000iu.

Her past history included a left sided illeofemoral DVT in 2004, an IVC thrombosis and a right sided popliteal DVT in 2008. She then commenced lifelong anticoagulation with warfarin and received an IVC filter and right sided internal and common iliac stents. In 2015 her stents clotted and she was commenced on lifelong therapeutic tinzaparin. Her thrombophilia screen under haematology was negative for any underlying condition.

Access to U/S over the weekend is extremely limited, usually patients are discharged on LMWH and an U/S is done during the week as an outpatient. In this case the suspicion of a proximal DVT must be established, as 50% develop a PE and the patient is already high risk. 

EPPU was preformed, which demonstrated non-compressibility of the left common iliac vein. This was instrumental in acquiring a departmental ultrasound which confirmed a proximal DVT.

This patient was admitted and a CT Peripheral Venogram found complete thrombosis of the intrahepatic IVC, both distal renal veins and left internal and external iliac veins. These findings warranted an urgent catheter thrombolysis and IVC filter removal. 

Recommendations

This unusual case highlights the value of an objective physical exam, bearing in mind up to 5-7% of patients on anticoagulation for VTEs can develop a recurrence. Current guidelines recommend dose escalation in the event of proven recurrence, therefore investigation is justified. In this patient’s case, urgent thrombolysis was warranted. EPPU, despite its shortcomings, has a high sensitivity and specificity and can be instrumental in the expedited care of select cases.


Amir ALSAFFAR (Galway, Ireland), Mustafa MEHMOOD
08:30 - 17:40 #10911 - Respiratory distress secondary to a hemorrhagic cyst on goitre compression.
Respiratory distress secondary to a hemorrhagic cyst on goitre compression.


Patient 78 years, presenting as main antecedents; Evolutionary neoplasia of the prostate without secondary sites under hormone therapy, under Arixtra for a segmental pulmonary embolism diagnosed shortly, is admitted to the emergency department for the price of a charge of an acute installation dyspnea for 48 hours in an apyretic context. Clinical examination of the patient was dyspneic with both dysphonia and wheezing. Auscultation found sibilant at the apex. The saturation was 96% in ambient atmosphere, the hemodynamics were stable. There was no alteration of the general condition, nor cervical tumor syndrome, nor peripheral adenopathy. The biological evaluation found a leucocytosis with 12100 / mm3 predominant neutrophil isolated polynuclear cells without deglobulation. The CRP was at 2.7 mg / L). Blood ionogram, renal function and liver function tests and normal. The chest x-ray of the face (Fig. 1A) revealed an enlargement of the mediastinum with deflection and tracheal compression. Despite the rapid introduction of IV corticosteroid therapy associated with antihistamine, the patient requests a respiratory distress requiring an orotracheal intubation. The cervicothoracic CT performed after intubation resulted in a 6 cm × 11.5 cm thyroid goiter extending up to the hull height and a bulky recent hematoma of more than 6 cm x 7 cm in diameter compressing the trachea (Fig.1 B) in the axial plane and 7.8 cm in the sagittal plane (Fig.1.C).

The respiratory symptoms of cervico-thoracic goitres are frequent and predominate over other compressive signs. A retrospective study of 117 patients operated on a retrosternal goitre noted preoperative dyspnea in 39% of cases, whereas dysphagia was present only in 16% of cases (1). Intrathyroid hematomas are very rare, but only the three cases have been reported in the literature. Two cases of spontaneous hematomas of the thyroid compliments of compressive syndrome were treated by emergency surgery (2). The placement of an endotracheal prosthesis is a good alternative to emergency surgery, considered to be random and dangerous. Our patient benefits from a hemityroid from left to D2. The postoperative follow-up was simple. The histology confirms the presence of an encapsulated macro-nodule of 8 cm × 6 cm × 4 cm with haemorrhagic remnants, necrotic without signs of malignancy

(1)Ayache S, Mardyla N, Tramier B, Strunski V. Clinical signs and correlation with radiological extent in a series of 117 retrosternal goitre. Rev Laryngol Otol Rhinol 2006;127:229–37.

(2)Chang CC, Chou YH, Tiu CM, Chiou HJ, Wang HK, Chiou SY, et al. Spontaneous rupture with pseudoaneurysm formation in a nodular goiter presenting as a large neck mass. J Clin Ultrasound 2007; 35:518–20.


Hakim SLIMANI, Charles Eric LAVOIGNET, Luc SENGLER (Belfort)
08:30 - 17:40 #11120 - Resuscitation team in hospital system - our experiences.
Resuscitation team in hospital system - our experiences.

BACKGROUND: Basic life support (BLS) is a level of medical care which is used for persons of life-threatening illnesses or injuries until they can be given advanced life support which  can be provided by trained medical personnel. Every hospital in health care system should have professional team for providing resuscitation services. Resuscitation team should be involved in training medical and nursing staff  as well as other health care professionals.                                                                                                             

AIM: Aim of this is paper is to show steps in implementation of resuscitation team in hospital system.

 

METHODES: Pub Med database was searched with the aim of finding appropriate studies and articles. This paper will show comparing pre test and final test  during the education of basic life support. Descriptive methods will be used to show analysis of efficiency of resuscitation team in 2016.

 

RESULTS: During two and a half years at University Hospital Centre Zagreb 1600 health care workers were included in basic life support course. Results of final test were usually better for 20% than pre test which gave us direct confirmation of increasing knowledge  about basic life support. Resuscitation team in 2016. has 48 interventions with average time of arrival of 5 minutes.

 

CONCLUSION: Providing education of basic life support for nurses and other health care workers assured results in higher level of knowledge. Implementation of resuscitation team give systematic approach of providing resuscitation services and improving quality and patient safety in hospital. Increasing of knowledge of resuscitation should be  primary goal for every hospital management.

 


Adriano FRIGANOVIC (Zagreb, Croatia), Marija KADOVIC
08:30 - 17:40 #11125 - RETROSPECTIVE ANALYSE OF THE PATIENTS WITH SUBCARACNOID HEMORRHAGE.
RETROSPECTIVE ANALYSE OF THE PATIENTS WITH SUBCARACNOID HEMORRHAGE.

In this study, the  demographic data of the  subarachnoid hemorrhage patients who applied  to Emergency department were researched.

 The patients with subarachnoid hemorrhage applying to the emergency department between November the first, 2011 - November the third, 2016 were retrospectively reviewed from the hospital automation system and the patient files. 67 patients were found reasonable  to study in accordance with the criteria. The patients were examined according to their sexes,their ages,their seasonal distribution, the application types to the emergency, the emergency vital and examination findings, their affected brain regions,  the laboratory values of cases, the discharge-hospitalization status, and their mortality conditions.

 The obtained data were statistically evaluated. % 52,2 of the patients were male. The mean age was 55,82 ± 14,74 years. About three-quarters of the patients had consciousness changes,  %82.1 of them  had headache complaints,  %80,3 of them were found to have used anticoagulants,  %27,7 of them were found to have used cigarettes and that of %6.2 of them were found to have used alcohol. More than half of the patients didn't have any examination findings. CRP, WBC, neutrophil and lymphocyte counts were found  increased but Na, K and Cl values were found acceptable. %89,6 of the patients were taken to the hospital by the  ambulances and  % 85,1 of those patients were discharged from the hospital after the treatment was completed, and the mortality rate was found to be %3. No similar detailed studies have been found in the literature. This study has similar and different parameters with the ones in the literature. It is believed that the studies to be carried out will contribute the literature and lead to clarify this study. 


Sefa BAKAR (Edirne, Turkey), Ömer SALT, Mustafa SAYHAN
08:30 - 17:40 #11041 - Retrospective Analysis of the Patients who were Hospitalized from Emergency Department with the Diagnosis of Acute Pyelonephritis.
Retrospective Analysis of the Patients who were Hospitalized from Emergency Department with the Diagnosis of Acute Pyelonephritis.

In this study we examined the demographic data of patients who were admitted to the emergency department and diagnosed with acute pyelonephritis. The acute pyelonephritis cases were determined retrospectively from the hospital automation system and patient files between May 1, 2012 - May 1, 2016. 241 case records were reached. Demographic characteristics such as; distribution by season, complaints of arrival, family history, laboratory values, imaging examinations, and the type of treatment and hospital outcome were examined. %54.4 of the patients were female. The mean age of the patients was 66.00 ± 19.61 years. Dysuria was present in %47.1 of the patients, fever in %75.9, trembling in %45.6, flank pain in 50.2%, nausea in %36.5 and vomiting in %33.6. On physical examination, 57.3% of the patients had costovertebral angle sensitivity, %39.6 had dehydration, %34 had weakness, and 20.7% had hypotension. %34.9 of patients were on antibiotic treatment before admission , genitourinary system operation in %25.7, and %17 had urinary catether.. The total mortality rate was %1.2. Predisposing factors for acute pyelonephritis should be carefully questioned, hydration therapy is essential, and sepsis and septic shock patients should be cautious in terms of mortality. Considering that the patient does not have an unnecessary urinary catheter and compliance with the sterilization rules in the procedures performed will reduce the number of patients.


Sibel BAKIRCIVI, Ömer SALT (EDIRNE, Turkey), Mustafa SAYHAN
08:30 - 17:40 #10715 - Reversible cerebral vasoconstriction syndrome of the basilar artery: usefulness of basi-parallel anatomical scanning MRI.
Reversible cerebral vasoconstriction syndrome of the basilar artery: usefulness of basi-parallel anatomical scanning MRI.

Introduction:

Headache is one of the most common primary complaints presenting to the emergency departments. A subset of these headaches is described as thunderclap headaches (TCH), a hyperacute and severe headache with its reaching maximum intensity within one minute. The differential of TCH is broad and includes intracranial aneurysm, subarachnoid hemorrhage (SAH), cerebral venous thrombosis, caudocervical artery dissection, ischemic stroke, pituitary apoplexy, and intracranial infection. Another cause that has gained increased recognition in recent years is reversible cerebral vasoconstriction syndrome (RCVS). Up to this point the diagnosis of RCVS can only be confirmed by follow-up imaging demonstrating resolution of the blood vessels’ irregularities. Therefore, it is difficult to diagnose RCVS in the acute stage using initial neuroimaging such as computed tomography (CT) and magnetic resonance imaging (MRI). We report the diagnosis, and temporal course of RCVS by observing the outer appearance of the intracranial basilar artery in basi-parallel-anatomical-scanning (BPAS) in addition to MR angiography.

 

Case:

A 41-year-old previously healthy male was admitted to the emergency department for recurrent episodes of severe occipital headaches. His initial computed tomography and magnetic resonance imaging (MRI) of the brain were all normal as well as a normal cerebrospinal fluid analysis. Magnetic resonance (MR) angiography showed multisegmental luminal stenosis of the basilar artery. Basi-parallel anatomical scanning (BPAS)-MRI, illustrating the outer contour of the vertebrobasilar artery, showed multisegmental stenosis which was same appearance as on MR angiography. Thus, a presumed diagnosis of reversible cerebral vasoconstriction syndrome (RCVS) was considered. The patient was treated with oral lomerizine. Repeat MR angiography and BPAS-MRI 2 months later was entirely normal in keeping with the diagnosis of the RCVS.

 

Conclusion:

RCVS should be considered in the differential diagnosis when approaching patients with thunderclap headaches. Early and correct diagnosis is utmost important to make appropriate management and prognostic prediction. At this time, the goal in the evaluation is to rule out other causes such as SAH, primary central nervous system vasculitis and dissection, which overlap considerably with RCVS. Although its application is limited to the vertebrobasilar system, BPAS-MRI may have a supplementary role to MR angiography in the diagnosis of RCVS of basilar artery.


Yamamoto AKITAKA, Akitaka YAMAMOTO (Yokkaichi Mie, Japan), Ohmori YUKINARI, Akihiro SHINDO
08:30 - 17:40 #10961 - Reversible splenial lesion of the corpus callosum secondary to pneumonia.
Reversible splenial lesion of the corpus callosum secondary to pneumonia.

Introduction:  Reversible splenial lesion with transient alteration in intensity on MRI has been described in a handful of cases in the world.  It is also known as mild encephalitis/encephalopathy with a reversible isolated splenium of corpus callosum lesion.We aim to report  in this study  the finding in patient with completely reversible splenial lesion after pneumonia, mimicking acute infarction.  

Case Report: 48-year-old man was admitted to the ED, suffering from weakness and uneven walking increasingly for 3 days. Vital signs of him were tension:151/89 mm-Hg; beat:106/min;  fever:38,3°C. He had been diagnosed with pneumonia before admission.On neurological examination, he was alert and sound. The cranial nerves were intact. Muscle strength and tone were normal. Deep tendon reflexes were within normal limits, and no pathological  reflexes were observed. The coordination and sensory systems were normal. Brain  MRI  showed  focal lesion with hyperintensity in diffusion weighted image (DWI) and mild  restricted diffusion patern in apparent diffusion coefficient (ADC) on splenium of  corpus callosum but  radiological findings and anatomic localization were not for ischemic lesions.There was no enhancement in gadolonium-DTPA-enhanced  T1-weighted images. He was diagnosed splenium of corpus callosun encephalitis and interned to infectious diseases clinic.

Conclusion:  A transient lesion of the SCC(Splenial Corpus Callosum) is a significant but nonspesific finding. It is probably due to edematous and/or inflammatory changes of the SCC. It may be the only detectable change in patients with good prognosis, indicating a clinically mild form of encephalitis/encephalopathy. Transient intramyelinic edema or inflammatory infiltrate is the possible mechanism and further studies enrolling more related cases will be needed to confirm our finding. This case highlights the importance of exploring different aetiologies of splenial lesions to avoid misdiagnoses with more commonly seen conditions such as CVA (Cerebrovascular accident).

 


Mehmet UNALDI (Istanbul, Turkey), Ismet DOGAN, Didem AY, Ersen GUNDUZ, Soner ISIK, Kurtulus AÇIKSARI
08:30 - 17:40 #11911 - Review of Instruments Used in Hazard Vulnerability Analysis of Hospitals.
Review of Instruments Used in Hazard Vulnerability Analysis of Hospitals.

Study/Objective:

To perform a qualitative comparison of instruments used for hazard vulnerability analysis of hospitals.

Background

Analysis of hazard vulnerability is the process by which a hospital determines the relative priority of each potential threat to the organization when allocating resources for disaster preparation and mitigation. While all hospitals in the United States are required to perform a hazard vulnerability analysis annually and use their findings to guide planning efforts, no officially sanctioned instrument exists for this task. Thus, a variety of tools exist in the public domain to assist hospitals in analysis of hazard vulnerability.

Methods

Purpose: Describe the instruments used for hazard vulnerability analysis at acute-care hospitals

Format:Systematic review of HVA instruments, specifically a search of PubMed, DisasterLit, NLM Specialized Information Services, MedlinePlus, ASPR TRACIE, grey literature from 2000 to present

Inclusion Criteria: English language hazard vulnerability instrument, Applicable to acute-care hospital

Results

Overview: 496 total documents retrieved from databases reviewed, additional grey literature search, total of three (3) instruments identified:

  • Modified Kaiser Permanente Medical Center Hazard and Vulnerability Analysis Tool, Kaiser Permanente 2017
  • Community Hazard Vulnerability Assessment, Children’s Hospital Colorado 2013
  • Hospital Risk Assessment, Bonnie Henry, Brian Schwartz 2006

All instruments use rating scales to estimate probability and impact. Of the available instruments, two are Excel worksheets, the other is an analytic process with a risk matrix to interpret results. All instruments customizable to include site-specific threats. Risk is calculated using a different formula in each worksheet.

 

Limitations

Search strategy, English language

Conclusions

HVA instruments available to emergency planners are very limited in number. The reviewed instruments calculate risk in different ways. It is of concern that the hazard vulnerability analysis of hospitals in the United States may be skewed solely by the specific instrument chosen to perform the analysis, yet none of these instruments are validated. Our hope is that this review of available instruments will lead to further research into best practices result in the standardization of the hazard vulnerability analysis of hospitals in the United States.

Recommendations include the development and promotion of standardized instrument or set of instruments, instrument validation and improvement, and data tracking.


Doug ROMNEY (Boston, USA), Meg FEMINO, Ritu SARIN, Amalia VOSKANYAN, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #10890 - Revisiting white blood cell count as a diagnostic marker of infection in the Emergency Department.
Revisiting white blood cell count as a diagnostic marker of infection in the Emergency Department.

Introduction: Diagnosis of infections in the Emergency Department (ED) is based on a cluster of clinical and paraclinical arguments. The blood cell count is an affordable exam widely realized in this situation. However, neutrophilia alone is usually taken into account, whereas it is an unspecific marker and others elements of the white blood cell count seem more effective. The aim of the present study was to explore and analyze the efficiency of white blood cell count in positive diagnosis and severity diagnosis of several bacterial infections in the ED.

Methods: We present here a retrospective and monocentric study conducted in the ED of a urban teaching hospital in France (from September 2015 to February 2016). All patients with a diagnosis of prostatitis, pyelonephritis, appendicitis, cholecystitis, sigmoiditis or pneumonia where included. The elements of white blood cell counts and the C-reactive protein level were compared to those of a control group (non-infected patients).

Results: A total of 466 infected patients and 466 non-infected ones were included for statistical analysis. In the infected group, 135 patients had sepsis and 13 were in septic shock. The elements of the white blood cell count and the C-reactive protein level were all significantly altered in the infected group (p<0.001). The modifications seemed to increase with the severity level, especially for the eosinophil, basophil and lymphocyte counts that were significantly lower in sepsis (p<0.05). Neutrophilia was the most sensitive marker of the white blood cell count and had the widest area under curve (79.6%). Eosinopenia under 10/mm3 and lymphopenia under 700/mm3 offered specificity over 94% and positive likelihood ratio of 6.3 and 3.9 respectively. Performances of these two markers (mostly eosinopenia) were increased in urinary and biliary tract infections. Monocytosis over 1000/mm3 had a specificity of 88.4% and a positive likelihood ratio of 3.9. Combinations of white blood cell markers between them, with fever or with elevation of CRP level showed specificity over 97%.

Conclusion: Thorough analysis of the white blood cell count (each line) is a helpful ans simple tool for the diagnosis of sepsis in the ED. Eosinopenia is a cheap and forgotten marker of acute infection and other elements could also help physicians in their daily practices.


Sylvie CHABRIER, Charles-Eric LAVOIGNET, Joffrey BIDOIRE, Elena Laura LEMAITRE (STRASBOURG), Sarah UGÉ, Philippe KAUFFMANN, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11179 - Rib fractures: Elderly patients receive lower standards of care than younger patients.
Rib fractures: Elderly patients receive lower standards of care than younger patients.

Background

Rib fractures represent a significant proportion of trauma seen in Emergency Departments. There is often associated lung injury with contusion or haemopneumothorax. Analgesia and respiratory support represent the cornerstones of management. There is an increasing frailty burden in healthcare. Elderly patients have previously been shown to receive poorer head injury care than younger patients. This audit examined whether this is the case with rib fractures too.

Methods

Retrospective audit of all adult patients with rib fractures from primary traumatic events, who were admitted for active treatment to a district general hospital over a 6-month period (July-Dec 2015). Patients were identified through TARN, WebPACS imaging system and emergency department software database, cross-referenced then imaging and notes reviewed. Demographics and characteristics of injury were recorded, along with markers of care such as level of trauma call, maximum imaging, critical care and analgesia such as epidural or patient-controlled-analgesia use, and outcomes including length of stay (LOS) and 30-day mortality.

Results

43 patients identified for inclusion after review of 2461 imaging reports and 58 sets of notes. 15 (35%) not captured by TARN. 17 (40%) were low-energy mechanism (fall<2m). Median age 67 (range 32-96).  Median of 5 fractures (range 1-22). 8 had flail chest (19%). Median hospital LOS 6 days (range 1-25). Median Charlson Comorbidity Index was 4 (range 0-11). Median ISS peaked at 16.5 in age 51-60 but was still 9 at age 81-90 and 6 at 91-100. Overall 30-day mortality was 11.6%. Hospital trauma call decreased from 75% in age group 51-60 to 0% in age 91-100, with increase in ‘no trauma call’ from 25% to 100%. Full Trauma CT decreased 88% to 25% across these age groups, with 75% age 91-100 having only chest XR as maximum imaging. Primary critical care admission decreased from 50% age 61-70 to 0% age 91-100.  Elderly patients were less likely to receive advanced analgesia. Median LOS increased with age. 30-day mortality was 43% in age 81-90 and 50% 91-100, with no other patients dying.

Conclusions

Elderly patients receive less aggressive and lower standard care and have higher mortality and LOS despite less severe injuries. Earlier recognition of these injuries may facilitate improved care pathways and outcomes. Hospitals should have a lower threshold for hospital trauma call and trauma scan in elderly patients.


Neil ROBERTS, Ruth CREAMER (Truro, United Kingdom), Jonathan ABELES, James BUTLER, Emma HARRISON, Julia GIBB, Rebecca NORMAN, Jonathan OUTLAW, Laura SHEPHERD, Ben WARRICK
08:30 - 17:40 #11190 - Rib fractures: The challenge of creating a pathway of care at a district general hospital with no thoracic surgeon.
Rib fractures: The challenge of creating a pathway of care at a district general hospital with no thoracic surgeon.

Background

Rib fractures are commonly seen in Emergency Departments (ED). Analgesia and respiratory support represent cornerstones of management. With ongoing centralisation of specialties such as cardiothoracics, limitations on critical care capacity, and deskilling of non-critical care nurses at management of epidurals and chest drains, identifying an appropriate route through the hospital for these patients is an ongoing challenge. This audit examined current practice with the aim of creating a unifying pathway.

Methods

Retrospective audit of all adult patients with rib fractures from primary traumatic events, admitted for active treatment to a district general hospital over 6 months. Patients were identified through TARN, WebPACS imaging system and ED software database, cross-referenced then imaging and notes reviewed. Demographics, severity and characteristics of injury were recorded, along with pathway through the hospital, respiratory support and analgesic requirements, and outcomes including length of stay (LOS) and 30-day mortality.

Results

43 patients identified for inclusion after review of 2461 imaging reports and 58 sets of notes. Median age 67 (range 32-96).  Median of 5 fractures (range 1-22). 21 had pneumothorax (49%). 15 had haemothorax (35%). 11 received chest drain (26%). 8 had flail chest (19%). Median hospital LOS 6 days (range 1-25), with median ICU LOS 3 days (range 1-7). Median time in ED 339 minutes, longer than median individual specialty admissions (219-275.5 minutes). 19 (56%) patients did not receive tertiary survey. 12 patients went to Clinical Decisions Unit (28%), 11 to Critical Care (25%), 11 to Medicine (25%), 4 to general surgery (9%), 5 to orthopaedics (12%). 3 patients deteriorated and required Critical Care admission. 34 patients met cardiothoracic referral criteria but just 10 were discussed, with 3 undergoing transfer for rib fixation. No patients required invasive ventilation. 1 patient received non-invasive ventilation, with 3 patients receiving high-flow humidified nasal oxygen. Overall 30-day mortality was 11.6%. 2 patients received epidurals, 16 received patient controlled opioid analgesia. Regional trauma network guidance suggests, according to severity of chest injury, that there should have been 20 epidurals and 18 PCAs.

Conclusions

Patients with rib fractures currently follow varied pathways through the hospital. Poor tertiary survey rates increase likelihood of missed injury. There is significant under-referral to cardiothoracics, and significant under-analgesia. Implementing a pathway including early stratification to Critical Care according to a validated risk score, planned initial care on CDU by ED including performance of tertiary survey, patients not requiring care on surgical wards or Critical Care to be admitted under the respiratory physicians with multidisciplinary trauma service support, and PCA training for CDU and respiratory ward, should address the problems identified in this audit.


Neil ROBERTS, Ruth CREAMER (Truro, United Kingdom), Jonathan ABELES, James BUTLER, Emma HARRISON, Julia GIBB, Rebecca NORMAN, Jonathan OUTLAW, Laura SHEPHERD, Ben WARRICK
08:30 - 17:40 #11207 - Rib fractures: The challenge of implementing an analgesic protocol in a district general hospital with no thoracic surgical ward.
Rib fractures: The challenge of implementing an analgesic protocol in a district general hospital with no thoracic surgical ward.

Background

Rib fractures are frequently seen in Emergency Departments (ED). These patients form a unique challenge at hospitals with no thoracic surgeon. They suffer respiratory complications which general surgeons are not comfortable managing, but require advanced analgesia which respiratory teams are not comfortable managing. At our hospital, thoracic epidurals are currently managed on Critical Care, and patient controlled analgesia (PCA) only on Critical Care or surgical wards. A reactive approach currently decides analgesic method. This audit examined current practice against a proposed protocol using a validated ‘Chest Injury Score’ to prospectively stratify analgesia based on risk of deterioration.

Methods

Retrospective audit of adult patients with rib fractures from trauma, admitted for active treatment to a district general hospital over a 6-month period. Patients identified through TARN, WebPACS imaging system and ED software database, cross-referenced then imaging and notes reviewed. Demographics, severity and characteristics of injury were recorded, along with pathway through hospital, respiratory support and analgesic requirements, and outcomes including length of stay (LOS) and 30-day mortality.

Results

43 patients identified after review of 2461 imaging reports and 58 sets of notes. Median age 67 (range 32-96). Median 5 fractures (range 1-22). 8 had flail chest (19%). 40 (93%) had unilateral injury. Median hospital LOS 6 days (range 1-25), with median ICU LOS 3 days (range 1-7). 30-day mortality was 11.6%. 12 patients went to Clinical Decisions Unit (28%), 11 Critical Care (25%), 11 Medicine (25%), 4 general surgery (9%) and 5 to orthopaedics (12%). 3 patients deteriorated with poorly controlled pain and respiratory failure on the ward and required Critical Care admission. 10 patients (23%) received Acute Pain service referrals, with 5 receiving advanced interventions as a result. 2 patients received epidurals, 16 received PCA opioid. 20 patients had chest injury score>20, indicative of need for epidural under the new pathway, with 18 scoring 11-20 indicative of need for PCA.  14 (33%) patients had contraindications to neuraxial analgesia (spinal fracture, intracranial bleed, anticoagulation). Of these, 4 received PCAs and 2 deteriorated and were palliated.

Conclusions

At our hospital, this group of patients is significantly under-analgesed according to regional trauma network guidance. Changing the current ‘reactive’ analgesic protocol to one based around a risk score will lead to significant increases in advanced analgesia and require significant resource investment. The base ward outside Critical Care will need to be PCA competent in order to deliver this service. Ongoing audit of outcomes will be required to justify this investment. Given the high prevalence of contraindications to epidural, and predominantly unilateral injury pattern, techniques such as serratus anterior or paravertebral catheters may play a role in the future.


Neil ROBERTS, Ruth CREAMER (Truro, United Kingdom), Jonathan ABELES, James BUTLER, Julia GIBB, Emma HARRISON, Rebecca NORMAN, Jonathan OUTLAW, Laura SHEPHERD, Ben WARRICK
08:30 - 17:40 #10925 - Right flank pain and usefulness of bedside ultrasound in emergency department.
Right flank pain and usefulness of bedside ultrasound in emergency department.

Purpose: Bedside emergency renal ultrasonography performed and interpreted by emergency physicians with limited training and experience is increasing in use and gaining acceptance. Emergency renal ultrasonography concentrates on the focused presence or absence of hydronephrosis as is often seen in patients with acute flank pain secondary to renal colic. ED visit rates for urolithiasis increased from 178 to 340 visits per 100,000 individuals from 1992 to 2009. Therefore, it is a common condition in the ED. In many patients, bedside renal ultrasound may obviate the need for further diagnostic workup and speed the diagnosis and treatment of an emergency patient. We present a case of patient admited at ED with right flank pain and hematuria, the tipical presentation of renal colic.

Material & Methods: renal calculi are the most common cause of flank pain and hematuria, it is prudent to also closely examine the kidneys on bedside emergency ultrasound for abnormal findings beyond the mere presence or absence of hydronephrosis.

Results: 53 year old male, was admitted to the ER by right flank pain and hematuria. Bedside emergency ultrasound initially performed to look for hydronephrosis, showed a large right renal mass, and prompted further workup with CT of abdomen and pelvis. While ultrasound is less sensitive than CT for detecting renal masses, it is a convenient imaging modality with many potential benefits for the inicial ED workup of flank pain and hematuria.

Conclusion: emergency ultrasound helped to identify a renal mass in a patient who presented with hematuria and left flank pain, initially thought to be renal colic on clinical evaluation. Like most renal tumors, this patients symptoms overlapped with the typical presentation of renal calculi. It was the findings on clinical emergency ultrasound, that helped to identify the correct diagnosis and prompted the appropriate consultations to urologist, with a final diagnostic of Renal Cell Carcinoma.


Alberto Ángel OVIEDO GARCÍA (DOS HERMANAS (SEVILLA), Spain), Francisco LUQUE SÁNCHEZ, Margarita ALGABA MONTES
08:30 - 17:40 #11600 - Risk factors for sepsis-associated delirium.
Risk factors for sepsis-associated delirium.

[Purpose]

The aim of this study was to investigate risk factors for sepsis-associated delirium (SAD).

[Methods]

From 2013 to 2016, we randomized 201 adult patients with sepsis under ventilation to receive sedation strategy with or without dexmedetomidine at 8 ICUs in Japan. We performed a nested cohort study of the RCT. 183 patients were included (86 delirium group and 97 non-delirium group). Delirium screening occurred daily using confusion assessment method for the ICU (CAM-ICU). Outcomes included 28-day mortality, ventilator-free day, length of ICU stay, self extubation and re-intubation. Multivariable analysis was performed to identify variables independently associated with SAD.

[Results]

There were no significant between-group differences in 28-day mortality, self extubation and re-intubation. The ventilator-free day was significantly shorter in the delirium group (median; 18 d vs. 22 d, p<0.001; delirium group vs. non-delirium group). The ICU length of stay was significantly longer in the delirium group (median; 11 d vs. 6 d, p<0.001). Multivariable analyses revealed renal replacement therapy (RRT) (OR 3.5, 95% CI 1.4-9.6), high-dose midazolam (OR 7.8, 95% CI 2.0-39.9) and high-dose phentanil (OR 5.4, 95% CI 2.0-16.6) as independent predictors for SAD (adjusted for APACHEⅡ score, shock, noradrenalin, dopamine, DIC, dexmedetomidine, propofol).

[Conclusion]

Among patients with septic shock under ventilation, SAD is associated with shorter ventilator-free day and longer ICU length of stay. RRT and high-dose midazolam or phentanil may be independent risk factors for SAD.


Tomonori YAMAMOTO (Shijyonawate, Japan), Maiko ESAKI, Shinyama NAOKI, Shinichiro KAGA, Noda TOMOHIRO, Kenichiro UCHIDA, Tetsuro Nishimura TETSURO, Yasumitsu MIZOBATA
08:30 - 17:40 #10895 - Risk factors of pain underdocumentation and oligoanalgesia in an emergency department: a retrospective cohort study.
Risk factors of pain underdocumentation and oligoanalgesia in an emergency department: a retrospective cohort study.

Introduction

Pain is a leading complaint in all emergency departments (ED).  An inappropriate pain evaluation and documentation may lead to undertreatment.  The objectives of this study were (1) to evaluate whether pain was appropriately documented; (2) to identify risk factors for underdocumentation; (3) to evaluate whether pain was appropriately treated when documented.

Methods

Retrospective cohort study in the adult ED of a primary and tertiary care teaching hospital admitting each year 64’000 patients.  All patients > 16 years triaged with a complaint requiring pain evaluation accordingly to our triage system (Swiss Emergency Triage Scale) were eligible.  Demographic data as well as data on pain documentation and treatment, triage, ED trajectory were extracted from the electronic patient records.  Univariate and multivariate analyses were performed to identify predictors of pain underdocumentation and oligoanalgesia.

Results

During a 1-year period, 31'942 (49.5% of all admitted patients) adult patients where triaged with a presenting complaint requiring pain evaluation.  Pain was not documented in 13'591 patients (42.5%).  In multivariate analyses, risk factors for non-documentation of pain during ED stay were:  male gender (adjusted Odds Ratio (OR) 1.08 ; 95% CI 1.03-1.14),  foreigners (OR 1.08 ; 95% CI 1.0-1.15), non-French speakers (OR 1.26 ; 95% CI 1.15-1.30), unemployment (OR 1.44 ; 95% CI 1.33-1.55), asylum seekers (OR 1.77 ; 95% CI 1.35-2.33), admission by their own means (OR 1.63 ; 95% CI 1.53-1.74), no prehospital analgesia (OR 2.11 ; 95% CI 1.80-2.47),  lowest severity emergency level (OR 1.28 ; 95% CI 1.04-1.58) as well as traumatic (OR 2.32 ; 95% CI 2.16-2.50), dermatological (OR 2.87 ; 95% CI 2.57-3.21) or ophthalmological triage complaints (OR 26.79 ; 95% CI 21.12-33.99).

Among the 18'351 (57.5%) patients having their pain documented, only 3'272 (17.8%) had their pain treated during their ED stay.  Risk factors associated with undertreatment were:  pain intensity < 5/10 (OR: 3.89 ; 95% CI 3.56-4.25), admission by ambulance (OR 1.14 ; 95% CI 1.02-1.27), no prehospital analgesia (OR 1.47 ; 95% CI 1.22-1.77), lowest severity emergency level (OR 1.78 ; 95% CI 1.16-2.74) as well as admission for chest pain (OR 2.72 ; 95% CI 2.16-3.43), headaches (OR 1.94 ; 95% CI 1.57-2.40) or ophthalmological complaints (OR 8.34 ; 95% CI 2.03-34.37).

Conclusion

Underdocumentation of pain and oligoanalgesia are common in our ED.  Different social characteristics as well as specific triage complaints are associated with an increased risk of non-documentation during the ED stay.  These could be specifically targeted by interventions aiming at better pain documentation and management.


Marie ARZEL (Geneva, Switzerland), Majd RAMLAWI, Pierre-Alexandre POLETTI, Josette SIMON, François SARASIN, Olivier RUTSCHMANN
08:30 - 17:40 #10953 - Risk Management in the Emergency Department.
Risk Management in the Emergency Department.

INTRODUCTION   

Risk Management should be a part of day to day activities ie part of the departments quality management programme. The practical application of risk management starts from the entry of the patient in to the Emergency department (ED) and requires an effective patient processing system which includes an effective triage system and monitoring of waiting times. Staffing should reflect the case mix, workload, ED size, design, adequate equipment for case load, real time monitoring of emergency department activities and troubleshooting by Senior Medical and Nursing staff. Senior staff review of ECG, X-ray and pathology results is part of this process. 

OBJECTIVE

This study was carried out at George Eliot Hospital, Nuneaton to recognise the areas of risk in a medium sized ED, looking after nearly 70000 new patients per year, and prepare protocols to eliminate risk.

METHODS

Areas of risk were recognised during departmental meetings, feedback from doctors and nurses, various audits and review of complaints from patients.

RESULTS   

Patients were registered on arrival and were asked to wait for triage, which was carried out by a Senior Nurse and the patient was informed of the waiting time.

Waiting times to see the doctor by patients was reduced by increasing the number of doctors on the floor and increasing the number of Senior doctors in the ED.

Four hours protected teaching time was given to junior doctors, which improved their knowledge and improved their interaction with the patients.

Multiple audits were carried out to improve the outcome of patient management.

All complaints were regularly reviewed and changes were made so that similar problems did not occur again.

DISCUSSION

Risk management must begin for a patient as soon as they enter the department. A key step in reducing the incidence of adverse events is to identify the patients at highest risk. There is a risk associated with the surroundings and it is important to recognise these risk factors, acting on these immediately to reduce the risk of litigation and improve patient care.

Error is not the same as negligence. In Tort Law medical negligence is defined as failure to meet the standard of practice of an average qualified physician practicing in the speciality in question. There have been tremendous advances in medicine over the last several decades during which time litigation has also increased. These highly publicised advances may have raised the expectations of the public. Risk management strategies should focus first on the reduction of medical injury which is responsible for the majority of malpractice claims.

It is impossible to eradicate the risk factors but a reduction of risk was certainly possible.


Mohammad ANSARI, Pankaj KUMAR (BIRMINGHAM, United Kingdom), Ahmad ISMAIL
08:30 - 17:40 #11769 - Role of a Poison Centre in the management of suspected rabies infections.
Role of a Poison Centre in the management of suspected rabies infections.

Backgroung: Post-exposure prophylaxis (PEP) in suspected rabies human exposures must be applied according to the international guidelines and requires prompt administration of vaccine alone or combined with human rabies immunoglobulin (HRIG): incorrect PEP can be related to a 100% fatality rate. During the last years, Pavia Poison Control Centre (Pavia-PCC) registered an increase of specialistic advise request for the clinical management of potential rabid patients and/or for vaccine/HRIG supplies. Even if Italy is declared free from urban rabies since 1973, sporadic cases of infected animals (north-east) as well as human rabies imported with fatal outcome have been identified. Objective: To evaluate the cases for which the Pavia-PCC provided advice for rabies. Methods: All human cases of suspected rabies (animals bite or scratch from suspected rabid animanl) were retrospectively analized (2007-2015) to evaluate in a real emergency field (i) the applicability of the routinely adopted risk criteria, (ii) the adherence to national/international guidelines, (iii) the role of a National Reference Centre. Risk assessmnent was performed considering type of animal, geographic area and grade of cutaneous lesion. Results: 161 patients were included, mean age 31±23,29 years (4 months-85 years; 48,5% male). Sixtheen cases (10%) regarded travellers bitten in endemic areas (Asia, 43%; dogs in 57%) or patients bitten in Italy by an imported suspected animal. According to the adopted risk assessment criteria, patients were divided in four groups, for which the treatment has been assessed. Group-A (risk only for lesion, n=87): treated 5% (vaccine 3 cases, vaccine+HRIG 1 case); group-B (risk for lesion + geographical area, n=6): treated 33% (vaccine 1 case, vaccine+HRIG 1 case);  group-C (risk for lesion + geographical area + animal, n=16): treated 81% (vaccine 3 cases, vaccine+HRIG 13 cases);  group-D (risk only for lesion + animal, n=43): treated 32% (vaccine 7 cases, vaccine+HRIG 7 cases). No acute ADR to vaccine or HRIG administrations have been registered. No cases of human conclamate rabies were diagnosed. Conclusion: Data evidenced a important different clinical approach and management in emergency setting. In particular, cases at risck only for lesion/wound caractheristc are overtreated in 4,6%; on the contrary, cases at high risk for rabies (group-C) are undetreated in about 20% of cases. Actual international and national guidelines should be updated, also considering the constant surveillance of veterinarians, and applied/discussed in every single suspecrted cases. A critical revision of procedures for the emergency treatment of potentially rabies affected patient presenting in ED is required.


Marta CREVANI, Sara DI GIULIO, Valeria Margherita PETROLINI, Mara GARBI, Davide LONATI (PAVIA, Italy), Eleonora BUSCAGLIA, Carlo Alessandro LOCATELLI
08:30 - 17:40 #11472 - Role of C Reactive Protein as a prognostic biomarker in Community Acquired Pneumonia in emergency department.
Role of C Reactive Protein as a prognostic biomarker in Community Acquired Pneumonia in emergency department.

Introduction : 

Despite several studies, role of CRP levels as a predictor of prognosis in the course of Community Acquired Pneumonia (CAP) remains somewhat undefined. Purpose of the present study was to analyze relationship between CRP levels and existing predictive scores in terms of final outcome of the disease.

Methods :

This is a prospective and descriptive study in which CRP was measured in all patients admitted to emergency department with a recently diagnosed community acquired pneumonia which is confirmed clinically and radiological from January 2017 to March 2017. For all patients the Fine’s score, CURB65 and SOFA score were calculated. CRP levels were divided into intervals: a correlation is established between this intervals and the severity of the CAP:  evaluated by different preexisting scores and patient’s intra hospital and 30 days mortality.

Results :

A total of 53 patients were included.75, 5% were male and 24, 5% female. The mean age was 67 ± 15 years. The mean level of CRP was 208 mg/L. CRP levels at admission were higher in patients with severe CAP (CRP levels were more than 200 mg/L in 61, 5% of patients with grade 5 of the Fine‘s score). Non-survivors had highest CRP levels (CRP>200 mg/L in 58, 3% of dead patients). This study showed a significant positive correlation between patient serum CRP level and mortality (p=0.03) and a significant positive correlation between patient serum CRP level and their score on CURB-65 (p=0.016) and Fine’s score (p=0.014) in scoring system.

Conclusion :

CRP has a significant prognostic value in community acquired pneumonia and can be used as a marker of severity.


Rim HAMAMI (Tunis, Tunisia), Olfa DJEBBI, Houda NASRI, Saloua MANSOURI, Bassem CHATBRI, Ines GUERBOUJ, Ghofrane BEN JRAD, Khaled LAMINE
08:30 - 17:40 #10640 - Role of CT coronary Angiogram In Patients With Chest Pain.
Role of CT coronary Angiogram In Patients With Chest Pain.

Introduction

The routine evaluation of acute chest pain in most centres involves use of serial electrocardiography (ECG) and cardiac biomarkers mainly cardiac troponins. The primary goal of this evaluation is to rule out acute coronary syndrome (ACS). Although this strategy is successful at identifying high-risk individuals, many patients are still misdiagnosed.This raises the question of safety in discharging patients with chest pain from the ED. Improved diagnostic accuracy and risk stratification is needed, especially in younger patients.

Aims :

The aim of this study is to evaluate the role of CT coronary angiogram in assessment of low risk patients presenting to the ED with possible coronary artery disease.

Methodology

Retropective observatinal study conduted from 2015-2016.

Case notes of about 120 patients, who had presented to the ED with chest pain of suspected ischaemic origin, with TIMI scores of 0 -- 1 were analysed . All these patients had ECGs done in ED and were admitted for serial troponin assays. Once having negative ECGs and cardiac troponin assays, subsequently received CT coronary angiograms. According to these, patients with NICE IHD scores between 10-60% were decided suitable for CTCA. High sensitivity troponin assays were used.


Results :

  • 5 patients had incomplete case notes hence excluded. 76 males (63.33%) and 44 females (36.67%).

  • 106 patients had normal ECGs while 9 had nonspeci c changes and hence assumed suitable for  admission.

  • 114 patients were troponin negative and one patient was troponin positive and got referred to medical team.

  • Out of 115, 74 (64%) patients had normal CT coronary angiogram results and were discharged from emergency department.

  • 41 out of 115 patients, (35%), had abnormal CTCA results.

  • 7 out of 115 patients, (6%), had minor disease.

  • 11 patients, (9.5%), had multiple plaques identi ed in the CT angiogram results but did not

    have any signi cant stenosis.

  • 17 out of 115, (14.7%), patients were found to have significant coronary artery disease and

    were referred to cardiology for follow up. 

  • 6 patients, (5%), patients were found to have other diagnosis.

    Conclusions

  • 9.5% patients were identified as having multiple plaque disease and these patients may require preventive management.

  • 15% patients were identifed to have signifcant coronary artery disease and these patients may well be at risk of a major cardiac event, and this may be preventable with early intervention.

  • Patients identified as having normal CT angiograms can be safely discharged from the ED . Hence, CTCA use, clarifies the diagnosis in patients with chest pain.

  • Recommendations

    • CT coronary angiography should be used early in the risk stratification of patients presenting to the ED

    • Early outpatient CTCA is safe after careful ED assesment , However, if clinical concerns exist then an inpatient CTCA should be obtained.

    • Emergency departments need to have well documented protocol, which should be agreed by radiology and cardiology teams .


Rashid KHAN (Birmingham, United Kingdom), Hamid ILYAS, Obaidullah ZAFAR, Ola ERINFOLAMI
08:30 - 17:40 #9889 - Roles of HIF-1α, VEGF and NF-κB in ischemic preconditioning-mediated neuroprotection of hippocampal CA1 pyramidal neurons against a subsequent transient cerebral ischemia.
Roles of HIF-1α, VEGF and NF-κB in ischemic preconditioning-mediated neuroprotection of hippocampal CA1 pyramidal neurons against a subsequent transient cerebral ischemia.

Purpose: Ischemic preconditioning (IPC) provides neuroprotection against subsequent severe ischemic insults by specific mechanisms.

Methods: We tested the hypothesis that IPC attenuates post-ischemic neuronal death in the gerbil hippocampal CA1 region (CA1) throughout hypoxia inducible factor-1α (HIF-1α) and its associated factors such as vascular endothelial growth factor (VEGF) and nuclear factor-kappa B (NF-κB).

Results: Lethal ischemia (LI) without IPC increased expressions of HIF-1α, VEGF and p-IκB-α (/and translocation of NF-κB p65 into nucleus) in CA1 pyramidal neurons at 12 h and/or 1 day post-LI, thereafter, their expressions were decreased in the CA1 pyramidal neurons with time and newly expressed in non-pyramidal cells (pericytes), and the CA1 pyramidal neurons were dead at 5 days post-LI, and, at this point in time, their immunoreactivities were newly expressed in pericytes. In animals with IPC subjected to LI (IPC/LI)-group), CA1 pyramidal neurons were well protected, and expressions of HIF-1α, VEGF and p-IκB-α (/and translocation of NF-κB p65 into nucleus) were significantly increased compared to the sham-group and maintained after LI. Whereas, treatment with 2ME2 (a HIF-1α inhibitor) into the IPC/LI-group did not preserve the IPC-mediated increases of HIF-1α, VEGF and p-IκB-α (/and translocation of NF-κB p65 into nucleus) expressions and did not show IPC-mediated neuroprotection.

Conclusions: In brief, IPC protected CA1 pyramidal neurons from LI by upregulation of HIF-1α, VEGF and p-IκB-α expressions. This study suggests that IPC increases HIF-1α expression in CA1 pyramidal neurons, which enhances VEGF expression and NF-κB activation and that IPC may be a strategy for a therapeutic intervention of cerebral ischemic injury.


Jun Hwi CHO, Chan Woo PARK (Chuncheonsi, Republic of Korea), Yoon Sung KIM, Joong Bum MOON, Taek Geun OHK, Myoung Chul SHIN, Ki Joong KIM, Ka Eul KIM, Moo Ho WON
08:30 - 17:40 #11434 - Round off decision-making: Why do triage nurses tend to categorize to the average patient with STEMI?
Round off decision-making: Why do triage nurses tend to categorize to the average patient with STEMI?

 

 

Abstract: By definition, patients with suspected ST Elevation Myocardial Infraction should be classified with high priority triage level in the Emergency Department (ED). Yet, half of these patients were given a low priority score, especially average classification (P3).

Aim: To identify significant factors in the triage process that result in P3 assignment for patients with ST Elevation Myocardial Infraction Diagnosis.

Methods. A retrospective-archive study was conducted at the Rambam Health Care Campus ED in the north of Israel from January 2015 to December 2016. We collected and measured patient’s characteristics, ED setting variables and hospitalization characteristics.

Results. The results show several key factors that affect the decision to assign P3 in the triage process. Analysis of the socio-demographic characteristics show that females (0R=1.96, P=0.05) and Arab ethnicity (0R=2.19, P=0.01) are significant when P3 is assigned. Number of cardiac events (P=0.02) was found to be the only noteworthy cardiologic comorbidity out of all that were reviewed.

A connection was observed between patient classified as average urgency and poor treatment outcome, namely regarding the variables time to physician, total time in the ED, Door to balloon time and mortality rates.

Conclusions. This research provides considerable data in identifying factors that affect the decision to classify chest pain patient as P3 and classification of P3 in the triage process altogether. Thus, demonstrating the extreme risk involve in the average classification during the triage process. 


Saban MOR (Zychron Yaakov, Israel), Lev ZARETSKY
08:30 - 17:40 #11956 - RTS : a system that calculates severity of patients use it in prehospital base for Air medical transport in Greece.
RTS : a system that calculates severity of patients use it in prehospital base for Air medical transport in Greece.

INTRODUCTION

The Revised Trauma Score is a physiological scoring system, with high inter-rater reliability and demonstrated accuracy in predicting death. It is scored from the first set of data obtained on the patient, and consists of Glasgow Coma Scale, Systolic Blood Pressure and Respiratory Rate.

Values for the RTS are in the range 0 to 7.8408. The RTS is heavily weighted towards the Glasgow Coma Scale to compensate for major head injury without multisystem injury or major physiological changesThe RTS correlates well with the probability of survival/death :

HYPOTHESIS:

The severity of the Aeromedical transferring incidents also varies, and it is also assumed that the final outcome of the Aerodynamic incident justified(?). the all try Is RTS reliable to predict the final outcome of these cases?

METHOD :

We calculate the rts for more than 2300 cases that aeromedical transported to the main Hospitals in Athens

The results are shown in shapes below: 

1. Distribution of RTS among the all of cases

2. Distribution of RTS per final outcome (death/survive/same

3. Distribution of RTS per outcome (death/survive/same)

CONCLUSIONS:

  1. RTS is a scoring system easily established, easily calculated, easily repeated
  2. although planed for trauma patients is reliable to predict death for all the patients
  3. It is questionable if rts is good enough to predict the patient & the final outcome in prehospital state

Evaggelos PAPANIKOLAOU, Vasilis KEKERIS, Spyros PAPANIKOLAOU (ATHENS, Greece), Spiros DIMITROPOULOS
08:30 - 17:40 #9946 - Rufinamide pretreatment attenuates ischemia-reperfusion injury in the gerbil hippocampus.
Rufinamide pretreatment attenuates ischemia-reperfusion injury in the gerbil hippocampus.

Objectives: Rufinamide, a voltage-gated sodium channel (VGSC) blocker, is widely used for the clinical treatment of seizures associated with Lennox-Gastaut syndrome. Previous studies have demonstrated that VGSC blockers have neuroprotective properties against ischemic damage following experimental cerebral ischemia. However, protective effects of rufinamide against cerebral ischemic insults have not been addressed. Therefore, in the present study, we firstly examined neuroprotective effects of rufinamide using a gerbil model of transient global cerebral ischemia.

Methods: Gerbils were established by the occlusion of common carotid arteries for 5 min. The gerbils were divided into vehicle-treated sham-operated group, vehicle-treated ischemia-operated group, 50 and 100 mg/kg rufinamide-treated sham-operated groups, and 50 and 100 mg/kg rufinamide-treated ischemia-operated groups. Rufinamide was administrated intraperitoneally once daily for 3 days before ischemic surgery. To examine neuroprotective effects of rufinamide, we carried out cresyl violet staining, neuronal nuclear antigen immunohistochemistry and Fluoro-Jade B histofluorescence staining. In addition, we examined gliosis using immunohistochemistry for glial fibrillary acidic protein (a marker for astrocytes) and ionized calcium-binding adapter molecule 1 (a marker for microglia).

Results: We found that pre-treatment with 100 mg/kg of rufinamide effectively protected pyramidal neurons in the hippocampal cornus ammonis 1 (CA1) area after transient global cerebral ischemia. In addition, pre-treatment with 100 mg/kg of rufinamide significantly attenuated activations of astrocytes and microglia in the ischemic CA1 area.

Conclusion: These findings suggest that rufinamide can display neuroprotective effect against cerebral ischemic insults and that its neuroprotective effect may involve the attenuation of ischemia-induced glial activation.


Jun Hwi CHO, Taek Geun OHK, Chan Woo PARK, Myoung Chul SHIN, Moo Ho WON, Joong Bum MOON (Chuncheonsi, Republic of Korea)
08:30 - 17:40 #9930 - SAFE ER.
SAFE ER.

SAFE ER

Getting Employees Involved
in Patient Safety

Patient safety initiatives are often related to changes in habits and work procedures. Changes, even related to patient safety issues, can be difficult to manage, especially if initiatives forcing employees to work more or different than they are used to or if the initiatives be accompanied by more documentation work load added to the primary patient process.

If employees are not engaged and not convinced about the necessity to think and work different they possibly see the entire initiative as "another change coming from the ivory tower”. As a result there is a high chance that the main goals will not be achieved. 

With the “SAFE ER” project we tried to inspire employees by involving them in the process to become safety a part of the day-to-day business of everybody. We asked employees to describe unsafe situations, habits or working processes they have been confronted with. Than we made photos with the employees to illustrate the dangerous or unsafe situation. All photos have been made 

The photos are presented on the ward in context with a quote, extra information about the specific safety related issue, protocols we are using to avoid the specific unsafe situation and statements from employees how they try to work safe. 

With the “SAFE ER” project we try to combine different factors to establish a safety culture in our emergency department:

Awareness:

By demonstrating possible dangerous/unsafe situations in the work environment with employees the level of abstraction is low

Role modeling and involvement:

Employees take initiative to show possible unsafe situations. By adopting to work safe on the photo and there statements they are stimulating others to do so

Understanding and conviction:

By using photos, even sometimes in an ironic way, we getting the point across of why working in a safer way makes sense

Developing knowledge and skills:

Bringing the photos in context with extra information about the specific safety related problem we can stimulate a learning effect without external pressure

“Safety is something
that happens between your ears,
not something you hold in your hands.”

Jeff Cooper


Alexander LECQ VAN DER (Leiden, The Netherlands), Christian HERINGHAUS
08:30 - 17:40 #11515 - Saturday night fever....
Saturday night fever....

The substance abuse is a frequent cause of admission to the Emergency Department posing many diagnostic and therapeutic problems, including those related to the onset of potentially fatal cardiac arrhythmias. In this study, the authors report their experience regarding the treatment of electrocardiographic abnormalities related to drug abuse with electrolyte abnormalities
In our retrospective study we have treated 100 patients (mean age 32 years, 87 males, 13 females) for drug abuse  with antidotal (where possible) or support, therapy monitoring, and electrolyte profile in order to prevent potentially fatal cardiac complications. All patients with severe cardiac complications (paroxysmal atrial fibrillation and ventricular tachycardia, total 11 patients) had a concomitant hypokalaemia (mean, 2.8 mEq / L, range 2.6 to 3.1 mEq / L),  in 4 patients hypomagnesemia (<1.4 mEq / L) was observed. These cases suggest a possible association between drug overdose and potentially fatal arrhythmias such as torsades de pointes, especially if associated with hypokalemia and hypomagnesemia.


Giorgio RICCI, Massimo ZANNONI (VERONA, Italy), Chiara BOVO, Lucia ANTOLINI, Gianni TURCATO, Mariano BELLONI
08:30 - 17:40 #10882 - SCREENING FOR HEALTH FRAGILITY IN THE EMERGENCY DEPARTMENT.
SCREENING FOR HEALTH FRAGILITY IN THE EMERGENCY DEPARTMENT.

Background : The consensus conference of December 5, 2003 suggests screening for health fragility in the emergency room, for patients aged 75 and over. The Triage Risk Screening Tool score (TRST) is one of the recommended tools. The objective of our study was to determine whether the elderly, 75 years and over, considered fragile based on the TRST score, are evaluated by the Mobile Geriatrics Unit (MGU) during intake at the emergency department of our Hospital Center.

Methods : We performed a prospective, analytical, descriptive and observational study, focused on a single site over a month (July 2015) during which all patients over 75 years were included after obtaining their agreement or that of the accompanying person. We did not make a declaration to the National Commission of Informatics and Civil Liberties (CNIL). The conditional probability of having a record of an MGU referral and review, with a TRST score greater than or equal to 2 was calculated. The agreement between the number of MGU reviews and the TRST score was tested using the kappa coefficient.

Discussion: 376 patients aged 75 years and over were included in the study. The fragility rate based on the TRST score was 93.8%. MGU evaluated only 14.6% of these patients at the emergency department. The conditional probability of having a record of an MGU referral and review, with a TRST score greater than or equal to 2 was 15.6%. The agreement between the number of MGU reviews and the TRST score was at best negative for a TRST score greater than or equal to 1.

Conclusion: To optimize the care for the frail elderly patient in the emergency department, the TRST score should be integrated in the screening process, for patients 75 and over. This integration would help raise awareness of the fragility of the elderly patient, and push toward increased consultation with the MGU.


Younes OUYACHCHI (LILLE), Essi TRONOU, Philippe PAMART, Marie TROCMET, Eric WIEL
08:30 - 17:40 #11784 - Seeing beyond the seizure: Myocarditis-induced status epilepticus.
Seeing beyond the seizure: Myocarditis-induced status epilepticus.

Status epilepticus is a relatively more common disease in patients with known seizure disorder. We present a 30-year old female patient with known seizure disorder who presented to the emergency department after having generalized tonic-clonic seizures. The patient failed to respond to the anticonvulsants and presumed to have status epilepticus. As per the relatives, the patient was said to be experiencing fevers, myalgia, malaise, and rhinorrhea for the last three days and skipped her routine anti-seizure medication.  The first differential diagnosis concluded by the treating physician was status epilepticus. The precipitating event was deemed to be medication noncompliance and the inflammatory response of the flu-like illness.  As part of diagnostic workup for the fever and flu-like symptoms, cardiac troponins were sent which came back elevated at 10,1 ng/ml. Other than mild sinus tachycardia, the patient did not have any physical examination signs suggestive of a cardiac disease and the sinus tachycardia could easily be attributed to status epilepticus. This case represents the importance of keeping a broad differential diagnosis and acknowledging the fact that more than one pathology can coexist in one patient.  In our case, the persistent nature of the seizures was merely a symptom of another ongoing process rather than disease itself.


Ceral Efe ARACI, Asiye Muminat GUNGOR, Hanife YENIGUN, Salahi ENGIN (Antalya, Turkey)
08:30 - 17:40 #10993 - Septic embolism after respiratory infection.
Septic embolism after respiratory infection.

Personal history: NAMC. Pilates teacher. Familial hypercholesterolemia.

Current disease: Case started about 14 days ago of dry cough, fever of up to 39º C of afternoon predominance, general malaise and arthralgia, which relates to flu episode. Since the 9th day of the begining, lumbalgia with mechanical characteristics is accentuated. 3 days ago begins with pain and inflammation at the left acromio-clavicular joint that is valued in the emergency room with diagnosis of cellulitis and begins treatment with Amoxicillin 1 gr. / Clavulanic 62.5 mg along with ibuprofen 6oo mg without clear improvement.

In the last hours, erythema begins in the right sternum-clavicular joint as well as in the sacral region with persistence of fever, greater deterioration of general condition and unquantified weight loss.

Physical examination: TA 119/72. FC 105 bpm. Temp. 37.7 ° C.

CyO. Mucocutaneous pallor. Well hydrated. Bad general state. Tachypnoid with broken speech. No neurological focal. No meningeal signs.

ACR: rhythmic and regular tachycardia without blows or extratons. MVC without added noise.

Abdomen soft and depressible. No masses or megalias or hernias are palpable. Diffuse discomfort to deep palpation in the left flank-hypochondrium without signs of peritoneal irritation. Preserved peristalsis.

Articular: Arthritis in left acromio-clavicular joint and right sternum-clavicular joint. Palpation discomfort on a column at the level of lumbo-sacral transition without accurate localization on spinous processes. Lassegue right doubtful.

Supplementary tests:

- Rx thorax: Increased bronchovascular weave in both bases. Small occupation costodiaphragmatic sinuses.

- Lumbar sacral column: Rectification of physiological curvature.

- Blood test: Hb 9.7 gr / dL, Leukocytes 27.52x103 (neutrophils 93.4%), GOT 187, GPT 157, total bilirubin 0.6 mg / dl. PCR 289. Procalcitonin 1.66 ng / ml.

- Lumbar MRI: Recumbent lumbar spine. Spondylitis L5-S1 with inflammatory changes perivertebrales and abscess of 17x32 cm in left iliac muscle.

- TAC abdomen: Spondylitis L5-S1. Abscesses in right gluteus and left piriformis muscle.

- Echocardiography: No alterations. No vegetation is visible.

- Blood culture positive for Streptococcus pneumoniae.

Evolution:

During plant admission, the patient presented fast and good progression with antibiotic parenteral treatment with ceftriaxone 2 gr. and cloxacillin 1 gr. started in the emergency room with remission of abscesses and was discharged in 2 weeks with complete remission.

Conclusions:

Streptococcus pneumoniae is a common causal agent of pneumonia and bacteremia. The presence of arthritis due to it is considered infrequent but as a result of this case and reviewing the literature seems to present with some frequency in the context of primary respiratory infection without it is certain that in the majority of the patients a certain factor of immunocompromiso is described that in this case was not evident.


David NUÑEZ CASTILLO (SPAIN, Spain), Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO
08:30 - 17:40 #11918 - Septic shock after acute pancreatitis caused by leptospirosis.
Septic shock after acute pancreatitis caused by leptospirosis.

We report on the case of a 34-year old man referring to Emergency. The patient reports, in the last 15 days, asthenia, anorexia and a loss of weight of 4 kg, with repeated dizziness. In the last 3 days come cutaneomucous jaundice, vomiting and diarrhea. The patient has not traveled recently and has no obvious infection.Reception records his temperature at 33,6° Celsius, a symmetrical low blood pressure (at 75/40) on both arms,a regular tachycardia with 135 beats per mn, with blood saturation at 97 %, a running pulse, blotches at the knees and diffuse bruises. The patient is conscious with a Glasgow coma score rated at 15.During medical examination chest auscultation is normal, the abdomen is soft but painful in the right upper quadrant. No hepatosplenomegaly. Hydroaeric noises at normal level, no sign of liver insufficiencies or portal high blood pressure. Presence of melena at rectal touch.
The biological results show:
 -a lactic acidosis : PH = 7,30, Lactates = 3,90,
 - a major inflammatory syndrome : major hyperleucocytosis at 29,10 G/L  and  PNN 27,5 and  CRP = 82 mg/L.
- a major acute renal failure : creatinine = 627 µmol/L, urea = 75,4 mmol/L with no ionic problems
- perturbed liver functions : ASAT and ALAT = 4N (186 et 168), GGT normal, PAL slightly up at 144, Bilirubine conjugated at 24N (420),  lipasemia at 42 N.
-a perturbed hemostasis balance: major thrombopenia at 27 G/L,TCA = 0,82, TP = 90 %.
Emergency concluded to a diagnosis  of septic shock due to an acute pancreatitis complicated by multivisceral failure. A scan of abdomen and pelvis is performed, and concludes to an acute pancreatitis Balthazar C. As no argument for a biliary, tumoral, alcoholic or medicinal origin was found, and similarly no area of necrosis was found with the scan, which could explain the sepsis, the pancreatitis was probably due to original infection
Supplementary samples were realized. Only  the blood PCR for leptospirosis did give a positive result (Leptospira interrogans).
That is an  anthropozoonosis in warm and humid countries but it is found everywhere. It is due to a bacteria of type leptospira.
Rodents (rats and mice) are reservoirs of the disease, but also most of domestic and wild mammals. Contamination occurs by contact with urine, or water and ground soiled by urine of infected animals, with a transcutaneous or mucous  passage of leptospira. Sewage workers, miners, farmers are professions at risk, but swimming in fresh water is also risky.
Classically, the clinical picture has three phases:
1) Silent incubation for  10 days,2) Pré-icteric phase for 5 days :  high fever,  flu syndrome , skin rash, meningeal syndrome 3) Icteric phase for about 15 days. Liver injury , renal damage, meningeal suffering with lymphocyte meningitis, lung damage, haemorrhagic syndrome, but the symptoms are extemely polymorphic.The diagnosis rests on PCR ADN search on blood, urine et LCR.Hemocultures are rarely positive.Treatment rests on antibiotherapy,


Alexandre HENNIART, Frederic DELÉPINE, Eric REVUE (Paris)
08:30 - 17:40 #11283 - Serious life threatening multi-focal infection caused by Panton-Valentine Leukocidin producing Staphylococcus Aureus (PVL-MSSA) in a child.
Serious life threatening multi-focal infection caused by Panton-Valentine Leukocidin producing Staphylococcus Aureus (PVL-MSSA) in a child.

Primary pyomyositis in children is prevalent in the tropics and increasingly being recognised from temperate regions. Staphylococcus aureus remains the principle causative organism worldwide. Panton-Valentine Leukocidin (PVL) is a toxin produced by some strains of Staphylococcus aureus (< 2%) and can be expressed by both methicillin resistant (MRSA) and methicillin sensitive (MSSA) strains. PVL strain can however cause serious life threatening multifocal infections.

A healthy 13-year-old boy, who was a keen rugby player, attended the Emergency Department (ED) with a 5-day history of non- traumatic severe, worsening right-sided groin pain which radiated to the right iliac fossa and to the right lower extremity. Additionally, the patient complained of general malaise, anorexia and night sweats. On examination, he was unable to weight bear, and pain increased on active and passive movement, particularly on rotation at the hip.

Magnetic Resonance (MR) imaging demonstrated abscesses within the right iliac muscle and the right gluteal compartment. The patient was referred to Orthopedics and had an uneventful incision and drainage of the abscesses. Overnight, he rapidly deteriorated with an oxygen saturation of 80% on room air. A Computed Tomography Pulmonary Angiogram (CTPA) showed bi-basal consolidation in keeping with bilateral pneumonia and acute respiratory distress syndrome. A transthoracic echocardiogram showed evidence of a small pericardial effusion, but no evidence of endocarditis. Blood cultures had consistently grown PVL-MSSA (Methicillin Sensitive Staphylococcus Aureus). On second look procedure, pus was washed out from the right rectus femoris muscle and the ipsilateral hip joint. An isotope bone scan demonstrated no foci of infection. A third look procedure found that the patient had developed changes suggestive of osteomyelitis of the right iliac bone. A fourth look procedure found no pus in the muscles or joint. MR imaging revealed changes in the articular margin of the sacrum, in keeping with progressive osteomyelitis in the sacroiliac joint. Mild osteomyelitic changes were noted in the adjoining sacrum. A fifth look found no additional pus. The patient was discharged home after 41 days of stay in the hospital with oral antibiotics.

PVL-MSSA can cause cellulitis, abscesses, boils and carbuncles. The infection risks include close contact sports such as wrestling and rugby and sharing contaminated towels or razors. Personal hygiene measures should be advised, including hand-washing, not sharing towels and bath water, and using appropriate dressings over wounds especially in someone who is involved in contact sports. Early involvement of a microbiologist is advised in treating PVL-MSSA.

Reference: Shiekh HQ, Aqil A, Kirby A, Hossain FS (2015) Panton Valentine Leukocidin osteomyelitis in children: a growing threat. British Journal of Hospital Medicine, 76 (1). 18-24. ISSN 1750-8460.


Neda IRENJI (Swansea, United Kingdom), Nisha MALLYA, Suresh PILLAI
08:30 - 17:40 #11513 - Serotonin syndrome, a potential life threatening syndrome. A case report.
Serotonin syndrome, a potential life threatening syndrome. A case report.

A potentially life threatening syndrome, serotonin syndrome is precipitated by the over-activation of both central and peripheral postsynaptic 5HT-1A and 5HT-2A receptors due to use of serotoninergic drugs and substances. This syndrome is consistent with a combination of autonomic and neuromuscular hyperactivity and mental status changes. Serotonin syndrome may occur via serotoninergic drugs overdose, serotoninergic drug alone, illicit substance abuse or as a result of complex drug interaction in between two serotoninergic drugs that have different mechanisms. A multitude of drugs and illicit substances combinations can result in serotonin syndrome. 

A 33 years old male patient, with no known pathological conditions but known as a user of steroids and anabolic substances is admitted in the Emergency Department of County Emergency Hospital of Oradea for repeated seizures and post - seizure status. This is a case report from our Emergency Department. 


Ionut BOJOR (Baia Mare, Romania), Dacian JUCA, Monica SABAU, Remus MITRE
08:30 - 17:40 #11483 - Severe intentional iron intoxication: successful early treatment.
Severe intentional iron intoxication: successful early treatment.

Case report:

A 18 year old woman was brought to the emergency department after intentionally ingesting 60 tablets of Fero- Grad 500 (Ferrous sulfate with 105mg of elemental iron per tablet) 5 hours earlier. She had been feeling nauseous with abdominal pain and had vomited a black substance twice. She was asymptomatic on presentation, had normal hemodynamic parameters and clinical examination. Lab tests showed a microcytic anemia with a hemoglobin(Hb) of 9.1g/dl and mild leukocytosis. Serum iron was elevated to 463 mcg/dl at 5 hours post ingestion.Abdominal radiography (AXR) showed multiple radiopaque tablets in the stomach.Deferoxamine was started at 15mg/kg/hour, 1g was given in total. She didn’t receive activated charcoal. Remaining tablets were extracted via endoscopy .Protonpump inhibitors and gastric lavage with polyethylene glycol were started. She was admitted to the critical care unit for further treatment. Serum iron levels normalized the day after admission.

Discussion:

80% of the intentional ingestions are reported in young females who often take large doses. The intoxication is typically divided into 5 stages with the first one presenting as gastrointestinal (GI) irritation followed by an asymptomatic latent stage. Following stages correspond with progressive systemic deterioration and death. The latent stage is an interval at 6-24 hour post ingestion where GI symptoms resolve and may appear falsely reassuring. It is critical to differentiate in this stage from asymptomatic patients with low dose ingestion. Serum iron concentration between 4-6 hours post ingestion is useful to confirm the diagnosis and estimate the severity of the intoxication, although low iron levels do not exclude toxicity. AXR should be taken with significant symptoms or intoxications with >40mg/kg of elemental iron. Visualization of radiopaque tablets indicate a risk for progressive toxicity and can be used to guide GI decontamination. Endoscopy can initially remove large iron loads. The risk of gastric lavage and whole bowel irrigation following endoscopy outweigh the limited benefit, but it should be considered for patients with a significant number of pills in the GI tract. Activated charcoal should not be used due to its limited absorption of the elementary iron and strong coloring of the gastric mucosa making endoscopy more complicated. Deferoxamine, a specific chelating agent, is indicated in the presence of a radiopaque tablet on AXR, severe GI symptoms, high anion gap metabolic acidosis and peak serum iron concentration >500mcg/dl. 

Conclusion:

Iron intoxications should not be underestimated given wide public availability and potention severe toxicity. A asymptomatic gap may be present between initial GI irritation and further systemic deterioration. The presence of radiopaque tablets are used to guide GI decontamination. Activated charcoal is best avoided. Deferoxamine is a specific antidote that chelates excess iron and thus reduces further toxicity.


Maarten MICHILS (Brussels, Belgium), Evert VERHOEVEN
08:30 - 17:40 #11685 - Severe serotonin syndrome and death of 20-year-old male patient caused by lobar pneumonia and 3,4-Methylenedioxymethamphetamine ( MDMA) use.
Severe serotonin syndrome and death of 20-year-old male patient caused by lobar pneumonia and 3,4-Methylenedioxymethamphetamine ( MDMA) use.

Serotonin syndrome is a rare life-threatening condition  that may occur following use serotonergic medications or drugs and is well described in a literature. Even less often serotonin syndrome is diagnosed in young previously healthy patients.

We present the case of 20 - year – old male patient with no previous history of serious illness and usage serotonergic drugs, who developed serotonin syndrome after single use MDMA in combination with marijuana and simultaneously diagnosed lobar pneumonia with fulminant sepsis.

 Patient admitted in Riga East clinical university hospital Emergency department in critical condition with severe hyperthermia (over 42⁰C) and shock. Patient’s grandmother was awaken early in the morning  by his scream, find a patient awake , psychomotor agitated, with no verbal contact available. Upon ambulance arrival, patient had clonic seizures with no reaction to irritation. Information given by relatives was poor – patient came home after party last evening with no symptoms of any illness and felt healthy before.

Prehospitally patient underwent external cooling, rehydratation and was intubated with following ventilation. 10 mg Diazepamum was administered intravenously.

Upon arriving blood pressure was 71/43 mmHg, HR 130 BPM, SpO2 92%.   Laboratory finding : leucocytosis 15,88 10e9/L, K+ 8.92 mmol/L, Glu 3.08 mmol/L ,CK-MB 574,68 U/L, LDH  976,57 U/L, Troponin T-HS 922,3 ng/L, creatinine  194,68 mkmol/L, ALAT 96,42 U/L, ASAT 449,13 U/l; Blood gases: pH 7,124, pCO2 70,3 mmHg, pO2 -82,8 mmHg, HIV negative; Ethanol negative.  Streptoccocus Pneumoniae antigene express test was positive.

CT scan of thorax showed pneumonia of upper lobe of right lung; CT scan of brain showed initial cerebral edema. Based on this finding, sepsis caused by pneumonia and multiorgan failure was treated firstly. 55 minutes after admission, cardiac arrest ( ventricular fibrillation) occurred. 60 minutes CPR was without effect and patient died.

Toxicological test results received after patient’s death – MDMA (Extasy), Marijuana and Ethylenglycol found in urine sample.

Autopsy performed the next day showed petechial spots on the surface of epicardium, liver, spleen and lungs; erythrocytes extravasation and lymphocytic infiltration were results of increased permeability of blood vessels as a result of drug overdose. Also regions with acute ischemic zones in myocardium were found. Pneumonia was found in the upper lobe of the right lung in the stage of red hepatization.

Conclusion : Hyperacute manifestations, non-specific symptoms, pneumonia and the rarity of serotonin syndrome decelerated the ability to determine correct preliminary diagnosis and start specific therapy.  Express drug tests would be useful in cases with unclear anamnesis and typical presentation of serotonin syndrome.

 


Olga SALUKA (Riga, Latvia), Alona VIKENTJEVA, Andrejs OLESIKS, Aleksejs VISNAKOVS
08:30 - 17:40 #11729 - Severe symptomatic hyponatremia; serum sodium level 89.8 mmol/l in a child using tacrolimus following renal transplantation.
Severe symptomatic hyponatremia; serum sodium level 89.8 mmol/l in a child using tacrolimus following renal transplantation.

Background and Objective: Although Tacrolimus (TCL) is known to be nephrotoxic, it is a very commonly used immunosuppressive agent in renal transplantation. It is also known that renal transplant patients treated with tacrolimus have a predisposition to a severe hyponatremia. Here we report a 15-year-old girl using TCL following renal transplantation presented to the emergency department (ED) with the lowest serum sodium in the literature.  

Case report: The patient was admitted to the ED because of womiting, weakness, reduced urine output, syncope and confusion. The patient underwent renal transplantation 4 months ago. The post-transplant immunosuppression treatment consisted of TCL, prednisolone and mycophenolate mofetil. On initial physical examination, his body temperature was 36.9°C, pulse rate was 80 beats/min, respiratory rate was 28 breaths/min and blood pressure was 107/51 mm Hg. She had confusion and the Glasgow coma scale was 13 (E3V5M5).  Biochemical tets were revealed that sodium 89.8 mmol/l, chloride 76 mmol/l potassium 2.7 mmol/l, calcium 7.1 mg/dl, glucose 176 mg/dl, bicarbonate 19 mmol/l, uric acid 11.4 mg/dl, urine sodium 68 mmol/l, blood urea 240 mg/dl, creatinine 6.5 mg/dl and TCL level 9.5 ng/ml (range 5-20 ng/ml). Initially, she received a bolus of IV normal saline (20 ml/kg) and was ordered 3% hypertonic saline for the first four hours at a rate not to exceed a rise in serum sodium of 2 mmol/l/hour. First 4 hours the serum sodium had increased to 97 mmol/l. While within  72 hours of intravenous therapy, the serum sodium level increased to 131 mmol/l, blood urea and creatinine were decreased to 33 mg/dl and 1.6 mg/dl respectively. Although there was a significant improvement  in kidney function tests and hyponatremia no improvement was observed during her monitorization in neurological symptoms.  Magnetic resonance imaging (MRI) was performed and an axial T2-weighted MRI showed high-intensity abnormalities localized in the pons that is evaluated as a central pontine myelinolysis.

Conclusion: Since all other potential causes of hyponatremia were excluded , TCL associated hyponatremia was thought  in this patient.  This case highlights  that using TCL in renal transplant patients may cause severe hyponatremia despite of normal TCL level.


Mehmet Arda KILINÇ, Dr Ali YURTSEVEN (İzmir, Turkey), Caner TURAN, Sevgin TANER, Bulent KARAPINAR, Eylem Ulas SAZ
08:30 - 17:40 #11253 - Sharp force injuries in Scotland between 2001 and 2013: Sociodemographic characteristics of injuries related to all-cause, alcohol and assault.
Sharp force injuries in Scotland between 2001 and 2013: Sociodemographic characteristics of injuries related to all-cause, alcohol and assault.

Background:The number of weapons offences related to knives in Scotland has fallen since 2001. This study determined the incidence of sharp force injury (SFI) affecting patients over 15 years of age admitted to hospital in Scotland between 2001 and 2013. It aimed to examine whether the trends in assault-related SFI mirror those seen in criminal justice and, further, sought to explore the key sociodemographic determinants of SFI related to any cause, assault and alcohol.

Method:All inpatient hospital events with ICD-10 (international Classification of Disease-10) codes related to SFI recorded between 2001-2013 were retrieved from the Information and Statistics Division (ISD) of the NHS (National Health Service). Annual incidence rates by age, gender, geographical region and Scottish Index of Multiple Deprivation (SIMD) quintile were calculated using midyear population estimates. Injuries with supplementary ICD-10 codes for assault and/or alcohol use were also analysed. A Poisson regression analysis model incorporated the variables age, gender, time (year), geographical region and deprivation quintile to calculate relative risk.

Results:Between 2001 and 2013, 168,389 patients (128,924 male; 39,417 female) over the age of 15 years old had a diagnosis of penetrating SFI at the time of discharge or transfer from hospital. 18,278 patients had SFIs related to assault and 20,942 had concomitant alcohol-related diagnoses.

The incidence of all-cause SFI was highest among young and elderly male patients, resident in areas of deprivation and from the West of Scotland. Assault-related SFI had a similar pattern of incidence with the exception of with the exception of the over 75 age category where the incidence was low. Alcohol-related SFI were more evenly spaced across the lifespan but again did not affect the over 75s. While the incidence of all-cause SFI did not change markedly over the time studied, the incidence of assault-related injury showed a downward trend from 2009 onwards (0.39/1000 population to 0.19/1000 population) driven by a decrease in assault-related SFI among younger age groups.

The major determinants of all-cause SFI were younger or older age, male gender, deprivation and residence in the West of Scotland. For assault-related SFI major determinants were being young, male, deprived and resident in the West of Scotland and for alcohol-related SFI were being young, male, deprived and from the North of Scotland. All relative risk values for these categories were statistically significant.

Conclusions:The incidence of non-fatal assault-related SFI decreased in Scotland between 2001 and 2013, especially among younger age groups, mirroring the downward trend in weapons offences in this age group. However, the risk of sustaining an assault-related non-fatal SFI remains higher among those who are young, male, and socially deprived. Public health efforts need to maintain efforts in targeting these sectors of society to reduce this inequality gap.


Fiona MACFIE (Glasgow, United Kingdom), Alex MCMAHON, David CONWAY, Christine GOODALL
08:30 - 17:40 #10958 - Should i let them go? Study on the voluntary discharge of patients who attempted suicide visited emergency department.
Should i let them go? Study on the voluntary discharge of patients who attempted suicide visited emergency department.

Introduction: The purpose of this study was to analyze the characteristics and factors of voluntary discharged patients after suicide attempt and analyze the effectiveness of follow - up measures.

Method: Total 504 adult patients aged 19 years and over, who visited a local emergency medical center from September 1, 2013 to December 31, 2015 were enrolled in this study. We retrospectively reviewed the records. we analyzed the relationship with voluntary discharge group (VDG) among basic characteristics, suicidal attempt variables, outcome variables related to suicide attempts, and treatment related variables comparing with normal discharge group (NDG). Statistical analysis was performed using the R program. Chi-square test, univariate and multivariate logistic regression analysis were used as statistical methods.

Result: Of the total 504 suicide attempts, three hundred eleven (61.7%) patients were VDG and 193 (38.2%) were NDG. Among total 311 patients of VDG, 211 (67.8%) were female and 100 (32.2%) were male. There were statistically significant differences between VDG and NDG in terms of age, education level, marital status, physical health status, drinking status, presence of psychiatric history, suicide attempt method, suicide attempt acknowledgment, medical lethality, suicide attempt plan in future, psychiatric consultation, case management service agreement and intervention, and connection to community service, post-discharge psychiatric treatment, and place of discharge (emergency room or ward) (p <0.05). The multivariate logistic regression analysis about voluntary discharge showed that the odds ratio (95% confidence interval) of age, no response group in referent to college graduation or more group, no response group of physical status in referent to healthy group, low group of medical lethality in referent to high group were 0.99 (0.97-1), 3.47 (1.54-8.13), 2.54 (1.43-4.57) and 1.92 (1.11-3.35) respectively (p <0.05).The ratio of the patients who agreed to case management service in NDG were 68.4% (132/193), more than twice as likely as 34.1% (106/311) in VDG (p<0.05). The proportion of patients who completed the community service linkage were 18.7% (36/193) in NDG, compared with 7.7% (24/311) in VDG (p<0.05). In addition, the ratio of the patients who visited psychiatric outpatient department in NDG were 57.0% (110/193), more than four times as likely as 14.5% (45/311) in VDG (p<0.05).

Conclusion: Over sixty percent of suicide attempters discharged against medical advice. Even though case management services were effective in prevention and reducing voluntary discharge of suicide attempters and increasing the outreach rate of community and psychiatric outpatients. However, at least 80% of total suicide attempters were still unidentified whether they were linked community service. Afterward, further various aspects of national supportive measures besides strengthening case management service should be considered.


Heejun SHIN (Bucheon city, Republic of Korea), Hojung KIM, Shingyeom KIM, Heeju OH, Sunjin CHOI
08:30 - 17:40 #11230 - Should we always use ultrasound for central venous line?
Should we always use ultrasound for central venous line?

Purpose: To demonstrate the utility of ultrasound when a femoral central venous line is required.

Cannulation of a central venous line is required in critically ill patients in the emergency room, and should be a basic skill for emergency physicians (EP). Its main indications include the need for rapid fluid resuscitation, central administration of drugs, and hemodynamic monitoring in critically ill patients. Like any invasive procedure, it has a risk of complications, according to the literatura, it can be very variable, ranging from 5% -19%, amongst those risks are infections, thrombosis, injury of the greater vessels, bruising, arrhythmias, etc. There are already many studies confirming that the use of ultrasound guidance for central venous line (CVL) insertion in the Emergency Department reduces the rate of complications.

 

Materials and Methods: Case study of the diagnosis of a pseudoaneurysm of the femoral artery, which occurred after several failed attempts to insert a central venous catheter, without ultrasound, only following the classic guides for anatomical reference. The equipment used was a Sonosite M-Turbo, HLF38x linear probe 6-13 MHz.

 

Results: 72 year old female, in clinical situation of hemodynamic instability, with suspected urinary sepsis, which required the insertion of a CVL for hemodynamic monitoring and administration of fluids and drugs. The EP decided a femoral approach and, after several attempts, he could cannulate the vein, but within a few hours the patient has a swelling at the puncture site. Another colleague trained in point of care ultrasound, performed an ultrasound scan showing a large pseudoaneurysm of the femoral artery, due to accidental puncture of the artery during the previous blind procedure. After consulting with the vascular surgery service, it was decided a surgical repair was urgently required.

 

Conclusions: The current scientific literature shows that ultrasound decreases the overall incidence of complications when accessing VCL, even being the use of this technology mandatory in many Western countries, to avoid complications, such as in the case presented. According to current recommendations of the American College of EP and other international scientific societies, the basic skills of emergency physicians must include ecoguided central venous access; but in Spain we are still far from that all emergency physicians we are trained in the use of ultrasound in critical situations.


Francisco LUQUE SÁNCHEZ (Seville, Spain), Margarita ALGABA-MONTES, Alberto Ángel OVIEDO-GARCÍA
08:30 - 17:40 #10827 - Show Business For Ugly People - Using Drama Techniques To Improve Staff Experience.
Show Business For Ugly People - Using Drama Techniques To Improve Staff Experience.

Emergency Medicine is recognised as a stressful career. In the UK the NHS has been under extreme pressure particularly over the last 2 winters.  The Royal College of Emergency Medicine has highlighted the effect of this on their staff working in these conditions.

This talk describes a project, which is a narrative enquiry, undertaken by myself and Kerry Wykes (ED Matron) looking at staff experience and tactics to improve it.

In Part 1  we looked at the Karpman Triangle. This is a social model conceived by Steven Karpman ; a student of transactional analysis.The Triangle maps conflicted or drama intense relationship transactions. It looks at the connection between personal responsibility and power in conflict and the destructive and shifting roles people play. It identifies that individuals may adopt the role of either  victim, persecutor or rescuer in stressful situations. These roles are all dysfunctional.

We introduced this concept to staff via small group workshops. It was also presented via daily departmental ten minute sessions. This was done using a style of presentation termed PechaKucha.

In Part 2 we looked to see if we could get staff to change their behaviour and responses. To do this we attempted to recreate the experience of playing these roles and then reflect on what had happened, could we change this and the outcome of doing so.

To do this we used a style of theatre called Forum Theatre. This was developed by a Brazilian called Augusto Boal and was created as a forum to teach people how to change their lives.

In a Forum Theatre performance several scenes are acted out in which a character or is presented with a problem which appears insoluble and the scene ends unresolved. Following this another performer facilitates a discussion amongst the audience about what they have seen and any suggestions to improve the outcome. This also applies group dynamics to problem solving. The scenes are then re-run and audience members are invited to come on stage and ‘try out ‘some of their suggestions.

In our project a group of ED staff worked with masters students from the Royal Central School of Speech and Drama. We chose a multi –disciplinary team involving doctors, nurses, receptionists and domestic staff.

Over 3 days we used a variety of techniques to develop scenarios in which the main protagonist played the role of either  victim, persecutor or rescuer. These were all in ED settings and based on the staff’s own experience.

These were performed as a forum theatre production to an audience consisting of ED staff .We were able to facilitate the audience to reflect upon playing these roles and the outcome of this and also to experiment with ways in which they could change their responses and behaviour and see if that could produce a more positive outcome.

Feedback forms were presented to staff to establish if they felt that this experience had been beneficial.

 


Dr Heidi EDMUNDSON (London, )
08:30 - 17:40 #10143 - Single avr subtle st-elevation as an indication for an emergency pci.
Single avr subtle st-elevation as an indication for an emergency pci.

      Patients presenting with ST-elevation myocardial infarction (STEMI) represent 30% of all acute coronary syndromes (ACS) admitted to the hospital. According to the ACC/AHA guideline's for STEMI, acute STEMI is considered in:

     -new ST-elevation at the J point at least in two contiguous leads of ≥1,5 mm (0,15 mV) in leads V2-V3 in women, ≥ 2 mm (0,2 mV) in men ≥ 40 years, ≥ 2,5 mm (0,25 mV)  in men < 40 years and/or of ≥ 1 mm (0,1 mV) in other contiguous chest leads or the limb leads

     - acute MI with a RBBB

     - new LBBB

However, the simple referral ECG criteria for PCI have led to potential failure in identifying the STEMI equivalents. STEMI equivalents do not present with the classical ECG changes but represent acutely occluded coronary artery. They are often associated with the poorer outcome and a worse prognosis. Common STEMI equivalents are:

     - lead aVR ST-elevation : Left Main Coronary (Left Main Stem) occlusion

     - LBBB with Sgarbossa criteria

     - isolated posterior MI

     - De Winter ST/T wave complexes

     - hyperacute T waves.

Our case is a 55 year old man, who suddenly felt severe dyspnea while driving on the highway, compelling him to stay aside. EMS were dispatched, escorted by an emergency physician (the author). Upon arrival, patient presented with dyspnea (RR 20/ minute), worsening in supine position. He had a history of arterial hypertension with no regular medication. On auscultation, normal vesicular breathing sounds were heard. Initial BP was 199/110 mmHg, and ECG showed a sinus rhythm with frequent PVC's and subtle aVR ST-elevation. However, the patient had no other complaints (no chest pain). Tensiomin (ACI) 25 mg s.l. was given for control of hypertension and patient's BP came down to 150/90 mmHg, and breathing became quiet (eupnea). After stabilisation, the patient was transported for urgent coronary angiography, which proved LMS (Left Main Stem) occlusion and (LCx) left circumflex artery occlusion.  Subsequently, patient was referred for CABG.

Conclusion: Acute occlusion of the LMS is an infrequent but lethal form of AMI. As it causes extensive myocardial necrosis, LMS occlusion results in severe hemodynamic deterioration, frequently resulting in rapid fatal consequences. In-hospital mortality rate for this condition is very high, ranging from 83 to 94 % , regardless of the method of management.

Evidence suggests that ST-elevation in lead aVR, with or without minor ST elevation in V1 , and/or  inferolatral ST depression, is an independent marker of acute left main stem occlusion. It is sometimes difficult to identify those patients and they may not present to the primary PCI or even cardiology service due to the lack of classical clinical symptoms and ECG findings. If such ECG changes of LMS occlusion are missed, timely intervention may be delayed and chances for survival may be reduced. Therefore,  prompt recognition and early reperfusion have a vital importance.


Iryna DOMORATSKA, Iryna DOMORATSKA (Trencin, Slovakia)
08:30 - 17:40 #11608 - Sledging - have fun or have trauma?
Sledging - have fun or have trauma?

BACKGROUND:

Sledging is a very expected amusement for children in winter time in our country, but usually the finality of this activity is painful or even dramatic.

OBJECTIVE:

The aim of this study was to surprise the high incidence of trauma in the winter time, to describe the characteristics of the injury and the sledging environment that leads to childhood injuries.

MATERIAL AND METHODS:

A retrospective study of the pediatric emergency care unit database was performed. The study group consisted of 62 patients with age under 18 years, who were admitted to the emergency care unit of the Emergency Hospital for Children "St Mary" in Iasi, Romania, due to winter season 2016-2017, with sledging related injuries.

 

RESULTS:

In the group of 62 patients admitted in the emergency care unit, the average age was 12 (between 6 years old and 17 years old), with a predominance of male ( 72,5%) and  rural provenience ( 80%). The period of admittance was grouped in 14 days: 3 in December, 8 in January and 3 in February. Common mechanisms of injuries were collisions with stationary objects (tree, wall- 45,1%), falls ( 48,3%), and collision with motor vehicles ( 6,4%). 13 patients (20,9%)  have multiple injuries ( politrauma or policontusions), 49 have isolated injuries. The majority was bone fractures (26 cases, 17 on lower limb and 9 on upper limb), 10 cases with contusions (16,1%), 7 cranial or facial trauma (11,2%), 6 wounds (9,6%). We notice 6 cases with thigh-bone fracture. 40 children were hospitalized (4 in intensive care unit), 22 cases were resolved in emergency room. In all cases the outcome was favorable, there were no deaths. 

CONCLUSIONS:

Even our city is not a mountain town, and last winter there was only 3 weeks with snowy days, we have a lot of sledging injuries, moderate or severe. So the sledging remains a fun activity, we suggest that sledging should be performed in designated, obstacle-free areas and that children should always be supervised by adults.


Carmen OLARU, Valentin OLARU (Iasi, Romania)
08:30 - 17:40 #11175 - Small bowel faeces sign: when the clinical and radiological picture may not match.
Small bowel faeces sign: when the clinical and radiological picture may not match.

Small bowel obstruction and renal colic are crucial differential diagnoses for the emergency department (ED) doctor when a patient presents with abdominal pain. Both require prompt assessment, diagnosis and treatment, however, the typical clinical manifestations are completely distinct.

We report on a 66 year old woman who re-presented to the ED with vomiting and abdominal pain. Only six hours previously, she had been diagnosed with a simple urinary tract infection when her urine had tested positive for blood and leucocytes. An ultrasound of her renal tract was organised on the basis that the doctor who initially assessed her may have missed a renal calculus. While drinking water in preparation for the ultrasound scan, the patient began to vomit copious amounts of bilious fluid. An abdominal film was taken, which appeared to reveal a normal gas pattern. The ultrasound scan was also performed and confirmed the initial diagnosis – there was a right-sided renal calculus.

The blood results were unremarkable and the imaging was not consistent with a bowel obstruction that might explain her bilious vomiting. Additional information was required.

On further questioning the patient, she had opened her bowels normally the day before and had been eating and drinking that day. She had previously been well, having undertaken only minor diagnostic laparoscopic surgery forty years ago. On examination, her abdomen was not noticeably distended and remained generally tender but more so in the flank areas. At this late point in the presentation, she was displaying only two of the four cardinal signs of bowel obstruction: abdominal tenderness and vomiting, without absolute constipation or abdominal distension.

Clinically, the ED team had low suspicion of a bowel obstruction. Nevertheless, a computerised tomography (CT) scan of the abdomen and pelvis was performed in order to exclude the possibility. On review of the CT images and report, our attention was drawn to the small bowel faeces sign – an important but relatively rare radiological feature of small bowel obstruction. Identified only on 8% of CT scans performed where small bowel obstruction is suspected, there is a particularly strong indication of acute obstruction where distal collapse of the bowel is also demonstrated. The patient was subsequently referred to the surgical team for urgent treatment.

We cannot possibly predict whether or not this patient would have been diagnosed with bowel obstruction in a timely fashion on clinical grounds alone. However, it is possible that the recognition of this radiological sign in an otherwise atypical presentation may have saved this patient’s life. This case highlights the importance of CT as a diagnostic tool to support prompt life-saving treatment. We hope this case is of particular interest to the senior house officer working in the ED in the management of atypical cases of abdominal pain.


Trisha GUPTA, Thillainayagam SRIRAM (London, United Kingdom)
08:30 - 17:40 #11881 - Smoking habits and anti-CCP antibodies in patients with rheumatoid arthritis.
Smoking habits and anti-CCP antibodies in patients with rheumatoid arthritis.

Background:

Anti-cyclic citrullinated peptide (anti-CCP) antibodies show high specificity for rheumatoid arthritis (RA). The aim of the study was to investigate the correlation between smoking and high levels of anti-CCP antibodies in patients with RA. The secondary objectives were to evaluate the association between smoking and the disease activity and, respectively, radiological progression.

Methods:

The retrospective study included 147 patients diagnosed with RA in the Rheumatology Department based on the American College of Rheumatology (ACR) criteria. Anti-CCP antibodies were measured by enzyme-linked immunosorbent assay (ELISA) in the serum. The smoking habits of the patients were also assessed.

The other variables we evaluated were: the onset of the disease, the family history, C reactive protein (CRP) and erythrocyte sedimentation rate (ESR) levels, hand and wrist imaging. Disease activity was measured using DAS28 (Disease Activity Score based on evaluation of 28 joints). The present and past treatment of patients was reviewed.

Results:

The mean value of the anti-CCP antibodies was higher in smokers than in non-smokers (306 U/ml I vs. 289 U/ml) but the difference was not statistically significant (p>0.05). However, the study shows that smokers have a 2.33 fold higher risk of developing a form of RA with positive anti-CCP antibodies than non-smokers (p<0.05; r=0.15).

Smokers were more likely to develop a severe disease. There were no significant differences between the radiological progression of disease in smokers and non-smokers. However, smokers required switching to other therapies more often than non-smokers. Smokers were also more likely to require novel therapeutic agents such as biological therapies earlier in their treatment.

Conclusions:  This research study showed that there is no statistically significant increase in the level of anti-CCP antibodies in smokers as compared to non-smokers. However, smokers were more likely to develop RA with positive anti-CCP antibodies. The disease was more severe in smokers than in non-smokers.


Chirea GABRIELA (Bucharest, Romania), Sarbu ISABELA
08:30 - 17:40 #11459 - Snap project: a novel emergency department model of care utilising a senior medical access physician.
Snap project: a novel emergency department model of care utilising a senior medical access physician.

ED overcrowding is a widepread problem. Northern ED is the busiest in Victoria, and is chronically overcrowded. Northern ED performs poorly in terms of measurable ED performance (eg length of stay, time to bed request), when compared with other Victorian EDs of similar size.

Literature review reveals a variety of processes introduced to reduce overcrowding, including physician triage, fast track areas, senior streaming, and nursing flow coordinators. Each process targets patient throughput (or flow), which, in contrast to access block, is amenable to direct influence by ED processes. Literature review did not uncover any studies whereby a Physician was primarily responsible for patient flow.

The SMAP project is a prospective pre and post-interventional study to be conducted in the Northern Hospital ED. The intervention will involve one additional Emergency Physician shift per day, and the project will compare two distinct models of care with a pre-intervention control period. The second model involves an Emergency Physician being responsible for patient flow. The project will deliver evidence to support the most effective use of the additional staff resource.

The project will involve prospective collection of performance data across two consecutive phases of six weeks duration each, commencing February 6th, 2017, together with the review of data obtained from the period of twelve weeks prior to project implementation. 


Peter BAILEY (Melbourne, Australia, Australia)
08:30 - 17:40 #11795 - Socio Demographic and Other Related Predictors of General Disaster Preparedness Beliefs Based on The Health Belief Model in Yalova, Turkey.
Socio Demographic and Other Related Predictors of General Disaster Preparedness Beliefs Based on The Health Belief Model in Yalova, Turkey.

Introduction: Sociodemographic and disaster related factors such as ever experienced a disaster and had any emergency/disaster education have the potential to affect emergency preparedness beliefs and related behaviors. A better understanding of these factors will play a key role in disaster mitigation. The purpose of this study was to examine the predictors of general disaster preparedness beliefs.

Methods: The questionnaire consisted of validated scales assessing general disaster preparedness beliefs using the Health Belief Model and was administered to a convenience sample of 973 people in Yalova, Turkey. Multiple linear regression was used to test the association between the Health Belief Model scales, total general disaster preparedness belief score (computed by summing up all the HBM scales) and associated factors. This study (Project Number: 2015/BAP/125) was supported by Research Fund of the Yalova University.

Results: Educational status, having a disaster kit, number of children, and having any emergency/disaster education were significant determinants of general disaster preparedness belief score. Significant predictors of perceived susceptibility and perceived benefit were; educational status, number of children and having disaster kit. For perceived severity, significant determinants were; gender and number of children, whereas for perceived barriers, it was educational status, having a disaster kit, number of children, and having any emergency/disaster education. In the case of cues to action, having a disaster kit was the only significant determinant whereas for self-efficacy, gender, educational status, number of children and having any emergency/disaster education were the significant determinants.

Conclusion: Our findings showed that educational status, number of children, having a disaster kit and having any emergency/disaster education influenced general disaster preparedness beliefs. These predictors should be the focus of attention when planning programmes aimed at achieving higher levels of general disaster preparedness beliefs.


Ebru INAL, Kerim Hakan ALTINTAS (Ankara, Turkey)
08:30 - 17:40 #10862 - Solving shortage with a temporary ‘emergency’ physician – challenges and advantages.
Solving shortage with a temporary ‘emergency’ physician – challenges and advantages.

Background: Staffing emergency departments creates unique challenges due to the mandate to provide care 24 hours a day and the inability to restrict patient demand for services. Previous studies have shown a shortage of emergency physicians in many countries, and are asking for alternative staffing models. This study explores the challenges and advantages by outsourcing shifts to a group of known temporary ‘emergency’ physicians.

Methods: The study is a prolonged 6-months ethnographic study. Fieldwork consisted of app 700 hours of participant observations in an emergency department, 25 in-depth interviews with nurses, physicians, secretaries and the management of the department, and four focus groups with four nurses in each group. Written material such as work schedules was analyzed too. The empirical material was generated in autumn 2015 and spring 2016 in a medium-sized regional hospital located in Denmark.

Results: The emergency department is outsourcing shifts to a group of consultants in internal medicine. Because of their daily work in medical departments, these consultants are mainly working in the emergency department at weekends, where only one emergency physician staffs the emergency department. In 2015, the consultants covered 61% of the day shifts and 53% of the evening/nightshifts at weekends. In average, they covered 1.4 shifts per month. Outsourcing the shifts to a known temporary ‘emergency’ physician have advantages: 1) they are a known resource, 2) they become familiar with the department, and 3) the collaboration with the department, they come from, becomes easier, when they are at duty. However, there are challenges too: 1) lack of knowledge about surgery in terms of treatment and supervision, 2) lack of experience of how to coordinate the work within an emergency department, 3) the collaboration with the nurses changes, and 4) the emergency department cannot control how the temporary physicians solves the tasks.

Conclusion: The emergency department solves the shortage of emergency physicians with a group of temporary physicians, who acts ‘emergency’ physicians once a month. This solution to staff problems results in both advantages and challenges. Moreover, the use of temporary physicians could result in a lower quality of patient treatment at weekends.


Iben DUVALD (Aarhus C, Denmark)
08:30 - 17:40 #11865 - Spastic form of pulmonary embolism.
Spastic form of pulmonary embolism.

INTRODUCTION :

Pulmonary embolism in his spastic form is very rare. Multiple pathophysiological mechanisms are associated and several hypotheses may explain the occurrence of bronchospasm in pulmonary embolism. The role of mediators released during platelet aggregation remains the most discussed.

OBSERVATION :

We report a case of a woman aged 83,with medical history of  diabetes and hypertension who presented to the ED for  progressively worsening dyspnea since two months. On examination : patient was awake with GCS : 15,  tachypnaeic, with no signs of struggle, the oximetry pulse on air was = 87%, and the cardiopulmonary auscultation was normal. Blood pressure was = 120/70 mmHg;  pulse = 98 bpm. Furthermore,  we noticed turgid jugular veins, hepato jugular reflux, with no edema of the lower limbs. A point-of care sample gazometry showed a high alveolo-arterial gradient and hypoxemia. The T-waves were flat in the the anterior leads on electrocardiogram. The Chest X-rays showed a cardiomegaly with atelectasis. The Echocardiography  noticed dilated right cavities, PAH 50, grade 4, tricuspid regurgitation, LVEF 65%. The diagnosis of pulmonary embolism were considered after evaluating the probability ( Wells score = 3; Geneva Modified = 8) and we completed by a angio-computerized chest tomography  wich concluded to an endoluminal defect at the upper and left lobar bronchus. Cardiomegaly at the expense of the right heart chambers with (VD / VG) ratio> 1. Immediate oxygenotherapy with curative effective  anticoagulation was initiated. Evolution was marked by recurrent iterative episodes of bronchospasms with sudden carbonarcosis. Ulterior evolution was favorable after non invasive ventilation , continuous B2  mimetics inhaled and corticosteroids.

CONCLUSION :

Very rare cases of spastic pulmonary embolism  have been reported in the literature. However, the pathophysiological mechanism is not completely understood and several hypotheses have been advanced.


Imen MEKKI (Tunis, Tunisia), Hamed RYM, Hana HEDHLI, Wided DEROUICHE, Héla BEN TURKIA, Yasmine WALHA, Abderrahim ACHOURI, Chokri HAMOUDA
08:30 - 17:40 #11641 - Spinal cord compression, infrequent but lethal.
Spinal cord compression, infrequent but lethal.

Introduction: neurological urgencies are between 2.6% and 14% of medical emergencies. Despite the rarity of acute spinal cord compression, this pathology is a neurological emergency, a cause of disability and a vital risk, whose diagnosis is based on an adequate and meticulous medical history with detailed anamnesis and complete neurological examination, pillars that define the patient's clinical prognosis. The following is a case report about this disease.

Medical history: a 70-year-old man, on treatment with apixaban for paroxysmal atrial flutter. He went to the hospital emergency department due to stabbing pain in the central region of the thorax, as well as dysarthria of 20 hours of evolution, showing a decrease in strength in the left hemibody with difficulty in ambulation, requiring bladder catheterization due to urinary retention. Physical examination reveals mucocutaneous pallor and left hemibody claudication, without any other neurological alteration. Analytically, there is intense hematuria, a Polymerase Chain Reaction (PCR) of 4.98 mg/dL and leukocytosis with neutrophilia. After cranial Computed Axial Tomography (CAT), a hyperdensal image was observed in the posterior region of bilateral ventricular atrium, probably in relation to minimal intraventricular hemorrhage, and the thoracic spine CAT discloses a higher density image at the spinal cord level, in the anterior region at the height of tenth and eleventh thoracic vertebrae, of epidural appearance, suggestive of epidural hematoma. The patient is reevaluated at 8 hours, evidencing clinical worsening, with paresis of lower extremities and hypoesthesia of these, as same as involved the territory of twelfth thoracic and first lumbar vertebrae, so that he enters in Neurosurgery, being verified by nuclear magnetic resonance (NMR) extrinsic spinal cord compression.

Conclusions: acute spinal cord compression is a rare cause of consultation in hospital emergencies, being multiple etiology and manifestations, and may be masked with a banal clinic. At times it implies an irreversible neurological damage for the patient, its consequent deterioration of the quality of life and, in some case, a vital risk according to the location of the lesion. That is why you need an early diagnosis in order to perform a quick treatment. Given the suspicion of this pathology is essential to carry out an adequate and exhaustive anamnesis, affecting the onset and progression of symptoms. The detailed neurological examination confirms the diagnosis of presumption, which is based on the imaging tests, being the choice of NMR, since it allows a better evaluation as to the spinal affectation.


Diego DEL BARRIO MASEGOSA, Alicia Fabiana SALVATIERRA MALDONADO, Hider CABRERA MARTÍNEZ, Fernando JUANES TORANZO, Horacio RODRÍGUEZ GARCÍA, Isaac CORDÓN DORADO, Carolina RICARDO JIMÉNEZ (Ávila, Spain)
08:30 - 17:40 #11630 - Spinal epidural hematoma.
Spinal epidural hematoma.

Case report:

Female 81 years old. With known pathological antecedents of: arterial hypertension. DM. Hypercholesterolemia. Anticoagulated atrial fibrillation. Mild to moderate mitral insufficiency. Moderate aortic insufficiency. Cognitive impairment. Tonsillectomy and bilateral phakectomy.

Direct anamnesis difficult by situation based on the patient, although it refers cervical pain of three days of evolution. They warn from the address to PA by BP of 170/110, indicate Ramipril and upon arrival they aim BP 140/90 mmHg and hypotonia upper left limb so they refer to the ER.

Physical examination: 

Vital signs: blood pressure: 140/95 mmHg, heart rate: 75 lpm Glucose: 195 mg / dl

Aware. Well moisturized and perfused. Eupneic. Neurological exploration: senile pupils. Fluent and coherent language. Canned cranial pairs. Engine system: generalized hypotonia, tetraparesis with pyramidalism (RCP bilateral extensor on hallus erectus), with predominant involvement of upper extremities. Sensitivity: perceives tactile and nociceptive stimuli in the trunk and extremities.

Investigations:

Glucose: 195 mg / dl. K: 2.9 mg / dl. Hematuria. Thromboplastin time 60.1 s. Prothrombin activity 15% INR 4.98. Thromboplastin time 56.1s. TTPA (ratio). 1.76.

CT scan: normal.

Contrast cervical MRI: Large posterior epidural collection up to 8 mm thick on both sides, extending from the vertebral body height from C2 to D3. It presents content with different signal intensities at T2 and homogeneously isointense at T1. This involvement causes a significant compromise of space in the canal, reducing the anteroposterior diameter of the marrow throughout this section, with minimal alteration of its signal intensity.

Evolution and conclusions: 

Started with progressive deterioration of the level of consciousness and desaturation, it is commented with the ICU that dismisses admission for not being subsidiary of invasive procedures. Exitus vitae.

With correct anamnesis and the complete physical examination is fundamental to obtain a good diagnostic approach and to be able to choose the correct complementary tests to arrive at a definitive diagnosis. Spontaneous epidural hematoma is a rare clinical entity that must be kept in patients who are anticoagulated, associated with poor control of therapeutic levels.


Carolina RICARDO JIMÉNEZ (Ávila, Spain), Ana Maria CHUCHÓN, Angel MACIAS LOPEZ, Maria MARTIN SANCHEZ, Miguel OTERO SOLER, Ruth SANTIAGO
08:30 - 17:40 #10893 - Spinal fractures with Diffuse Idiopathic Skeletal Hyperostosis in the ED.
Spinal fractures with Diffuse Idiopathic Skeletal Hyperostosis in the ED.

Introduction: Fracture of the spine in patients with Diffuse Idiopathic Skeletal Hyperostosis (DISH) is a rare condition that can be difficult to diagnose in the Emergency Department (ED). The main objective of our study was to profile patients at risk. Secondary objectives were to evaluate initial care and distance fate.

Methods: We present here a retrospective monocentric and observational study on the analysis of patients who, in a context of DISH, had spinal fracture. This study was conducted in a teaching hospital (regional trauma center), over a six years period (2010-2015).

Results: During the study period, a total of 909 patients had spinal fracture in our ED, 35 (3.9%) of them had spinal fractures on DISH. The sex ratio was 2.2 with an average age of 76.3±10.8 years. The majority of cases were reported as falls (74%), and patients were most likely to be consulted for spinal pain. Moreover, a total of 40 fractures on DISH were identified, some patients (n=5) had multiples locations. The location of the fractures was mostly dorsal (60% dorsal, 20% lumbar and 20% cervical). Five patients had a neurological complication. The radiographic study was able to make diagnosis of fracture in only 3 of the 10 radiographic performed, while the spinal CT scan was able to confirm the diagnosis in all cases. Finally, 22 patients required surgical treatment (stabilization surgery), 8 required a conservative treatment (orthopedic) and 5 of them had a functional treatment. The short-term complications were predominantly infectious, pulmonary (27%) and urinary (9%) in the surgical treatment group; complications were neurological (40%) in case of functional treatment chosen.

Conclusion: Because of the difficulty of visualizing these fractures on standard radiography, it is necessary to have a high level of suspicion when a trauma occurs in a context of DISH and to systematically realize a CT scan. Because of their high instability, these spinal fractures must be treated with stabilization surgery. There is no place for functional treatment, potentially responsible of serious neurological complications. Any spinal trauma occuring in a patient with DISH should benefit of a CT scan.


Fanny SCHWEITZER, Philippe KAUFFMANN, Carmen HAMMANN, Céline RENFER, Sarah UGÉ (Strasbourg), Claude GERONIMUS, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11066 - Spondylodiscitis – A clinical challenge in the Emergency department.
Spondylodiscitis – A clinical challenge in the Emergency department.

Spondylodiscitis is rare but its incidence is increasing and early diagnosis is challenging. The presence of other source of infection, absent neurology and prevalence of back pain in the general population can lead to diagnostic delays. We present a case of 78 years old male who was brought to our Emergency department by ambulance with neck pain was later diagnosed with Discitis at two different levels in his spine. The clinical and diagnostic challenges are very evident in this case especially the dilemmas in the Emergency department. The main learning points are that high index of suspicion for Spondylodiscitis and its inclusion in differential diagnosis for neck and back pain are the keys to early diagnosis thereby reducing morbidity and mortality.

Attached is the Abstract of the case report.


Gnana K SINGARAVADIVEL (Southend on sea, United Kingdom), Dalip KUMAR
08:30 - 17:40 #11908 - Spontaneous hematoma of the adrenal gland.
Spontaneous hematoma of the adrenal gland.

Introduction:

Adrenal hemorrhage (AH) is an uncommon condition with frequently nonspecific presentation varying from acute onset to accidental discover of an asymptomatic adrenal mass. Most of these cases are seen on inpatients acutely ill and hospitalized for other health issues. Undiagnosed in time, adrenal insufficiency may occur leading even to death if specific treatment is not established.

Case report:

A 73 years man admitted to the Emergency Department (ED) for abdominal pain with acute onset. He had a history of diabetes, Myocardial infarction with coronary bypass, gastric ulcer and a bladder cancer discovered six years ago undergoing a curative treatment. The patient described a pulsatile severe pain in his right hypochondrium estimated to 08 out of 10 on verbal rating scale. The patient had nausea but no fever and no history of recent trauma was identified. The patient was conscious at initial physical examination, anxious but no mental confusion. Hemodynamic outputs were correct : blood pressure of 120/70 mmHg, regular pulse rate of 90 min-1, breathing rate up to  22 min-1 and his temperature was 37.2°C.  The abdominal examination showed no sensitivity or abdominal guarding. Laboratory data of the patient showed no disorders. The hepato-biliary, pancreatic and renal functions were at the standards. Us Troponines and ECG were corrects.The abdominal CT scan performed at the ED showed an hematoma of the right adrenal gland of 4*2cm and the patient was admitted in the urology department for further investigations and treatment.

Conclusion:

Adrenal hemorrhage is a rare and unusual condition that ED physicians often forget to consider. AH is generally associated with trauma, infection, or bleeding diathesis. Few isolated cases of similar idiopathic adrenal hemorrhage were described in the literature and nearly all of them were postoperatively diagnosed as such. Though rare, signs of adrenal hemorrhage may include an asymptomatic adrenal mass and should be considered in the differential diagnosis of acute abdominal pain.


Bassem CHATBRI (Tunis, Tunisia), Rim HAMAMI, Mounir HAGUI, Saloua MANSOURI, Ines GUERBOUJ, Ghofrane BEN JRAD, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11708 - Spontaneous Hemopneumothorax : A Case Report.
Spontaneous Hemopneumothorax : A Case Report.

Spontaneous Hemopneumothorax : A Case Report

*Noha Ahmed Elgendy,** Mohammed Bakoush

*Emergency department  **cardiothoracic surgery department

(Monfya University Hospitals)

CASE PRESENTATION:Male patient 33 years old smoker with no past medical history referred from secondary healthcare facility complaining of chest pain and shortness of breath.He was referred to emergency department and initial evaluation was performed the patient presented with hemodynamic instability.During examination the airway was patent and secured HR140, BP70/40capillary refill time4 sec the patient was disoriented and confused.Chest examination reviled decrease chest expansion and air entry on the right side with oxygen saturation80% on high flow oxygen15liters.The patient started to be resuscitated with 2 liters warmed lactated ringer.Chest radiography showed a right massive pleural effusion with pnumothorax causing shifting to the mediastinum to the left side ant nearly total lung collapse.The patient was hemodynamically to be sent for immediatd(CT).A chest tube was inserted and drained about80mls blood on insertion and within5minuets the bleeding increased to1200.O negative blood started to be transfused and the patient was transported to operation room immediately,during transportation to operation room table the patient arrested with pulse less electrical activity rhythm,CPR initiated for tow cycles and ROSC after them.Right thoracotomy was performed.Post-operative recovery was uneventful and he was  admitted to ICU and extubated10 hours later.Stay in ICU was for four days and he discharged home well on ninth  post-operative day.

 DISCUSSION:spontaneous hemopneumothorax is a uncommon disease; previous reports state that it occurs in about 0.5%–12% of spontaneous pneumothorax patients.The mechanisms of spontaneous hemopneumothorax is the rupture of the vascularized bullae and underlying lung parenchyme.which was confirmed by the cardiothoracic sergons in this patient.So he had hemopneumothorax that was caused by the rupture of the vascularized bullae.the smoking index of the patient was 26 pack-year smoking history.The clinical feature of Spontaneous hemopneumothorax  is dramatic because of the hypovolemic shock by a rapid progress of symptoms.The goals of treatment include hemostasis and reexpansion of the lung. Setting up two large bore branulas and fluid with blood resuscitation accordingly and high flow oxygen using non rebreather reservoir, chest tube should be inserted under  a sterile technique to evacuate the haemothorax are the golden keys in management of the patient. Drainage should be assessed hourly for decision for surgical intervention 

CONCLUSION:Bleeding of a vascularized bullae in young adults should be list of differential diagnosis for a spontaneous haemopneumothorax.Early thoracotomy is preferred to control the bleeding in hemodynamicaly unstable patients 


Noha ELGENDY, Noha ELGENDY (Shibeen Elokm, Egypt)
08:30 - 17:40 #11558 - Spontaneous massive hemoperitoneum as initial presentation of gastrointestinal stromal tumor.
Spontaneous massive hemoperitoneum as initial presentation of gastrointestinal stromal tumor.

Introduction :

Acute abdominal pain is called the "surprise box" of emergency medicine. The etiologies are multiple but some causes are rare . Spontaneous hemoperitoneum (SH) is a rare, but lifethreatening condition of non traumatic etiology. Occasionally, such lesions may be the initial sign of Gastrointestinal stromal tumor in patients without any other clinical manifestations of the disease.

Case Report :

It is a 47-year-old patient with a medical history of hypertension. Admitted to the emergency department for diffuse abdominal pain with vomiting without transit disorders. The admission examination finds an apyretic patient in good general condition with a mucocutaneous pallor.Vital signs were pulse rate of 100 beats/minute, respiratory rate of 20 breaths/minute, and blood pressure of 100/65 mmHg. The abdomen was moderately distended having diffuse tenderness . His hemogram showed haemoglobin of 8.3 g/dl . An abdominal ultrasound performed showed a mid-abundance ascites with normal-sized liver and free bile duct. The patient was initially admitted to the gastroenterology department where he rapidly impaired his hemodynamic status. An abdominal angioscanner was requested which showed an appearance in favor of a Gastrointestinal stromal tumor with large hemoperitoneum and peritoneal carcinosis. The patient was transfused urgently . A guided scanno biopsy finds a morphological and immunophenotypic aspect in line with a Gastrointestinal stromal tumor (GIST) patient placed under Glivec and transferred secondarily in surgery departement to supplement management.

Conclusion :

In front of any abdominal pain with deglobulisation the emergency doctor must always evoke the hemoperitoneum so as not to miss a diagnosis that may involve the patient's prognosis.


Ines GUERBOUJ, Rim HAMAMI (Tunis, Tunisia), Mohamed GHANEM, Mehdi BELLASSOUED, Ghofrane BEN JRAD, Mounir HAGUI, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11929 - Spontaneous pneumomediastinum and subcutaneous emphysema due to cough and sore throat that began three weeks ago in 17 years old female.
Spontaneous pneumomediastinum and subcutaneous emphysema due to cough and sore throat that began three weeks ago in 17 years old female.

Spontaneous pneumomediastinum(SPM) is rare in younger ages and an average age of 17.5 to 25 years. SPM is self-limiting and benign in nature, and it usually occurs in young without any trigger events or diseases. A pressure gradient exists between the peripheral pulmonary alveoli and the hilum, and increased intraalveolar pressure causes rupture of the terminal alveoli. Alveolar rupture allows air to extend along the pulmonary vasculature towards the hilum, the peribronchial spaces, and subsequently, into the mediastinum. The most common symptoms at pre-sentation are the acute onset of pleuritic or retrosternal chest pain and dyspnea. Because of its low incidence and its mild intensity, the diagnosis can be easily missed.

A 17 years old woman presented to our Emergency Department with complaints of cough and sore throat for three weeks and was given medication by primary care physician. But she had worsening of dyspnea, continuous and progressive chest pain radiating to the her neck for last two days. The physical examination was significant for diffuse neck and chest subcutaneous emphysema. Cardiac monitoring revealed sinus tachycardia with a rate of 122/min, and her respiratory rate is 32/min, fever 37.2 °C and systemic blood pressure of 126/73 mm Hg. No rales were noted on the lungs. Laboratory datas were normal. Chest x-ray showed mediastinum emphysema with air extending to the tissue of the neck. Chest CT revealed marked air accumulation around the aorta, trachea, and pericardium. Her esophagography and endoscopy was normal. The patient was followed conservatively and fully recovered over the next 5 days.

SPM developed in this patient with no underlying lung disease, presumably from air leakage secondary to the excessive elevation of intrathoracic pressure due to cough. Pneumomediastinum is an uncommon disease arising most frequently and remains largely underdiagnosed clinically, especially in young, healthy patients. 

In most previous reports, the vital signs and general appearance of patients were normal, reflecting the benign course of SPM. Typically, SPM presents in young adults, and the incidence is low, in most emergency department referrals. Treatment for SPM is not specific, and it involves careful observation, bed rest, oxygen inhalation, and treatment with an-algesics. Sometimes, antibiotic prophylaxis is used to prevent the development of mediastinitis. 

In conclusion, SPM is a rare self-limited condition with a benign natural course in young healthy adolescents. SPM should be considered in the diagnosis of adolescents with pleuritic chest pain. Careful interpretation of initial chest X-rays is important for avoiding unnecessary investigations. CT scanning is important to diagnosing clinically suspected cases when chest X-ray is normal or equivocal. If there are no clues for esophageal perforation, urgent esophagography is not recommended.


Volkan ÜLKER (ISTANBUL, Turkey), Hilal HOCAGİL, Abdullah Cüneyt HOCAGİL
08:30 - 17:40 #11075 - Spontaneous rupture of renal angiomyolipoma resulting in wunderlich’s syndrome.
Spontaneous rupture of renal angiomyolipoma resulting in wunderlich’s syndrome.

Introduction :

Renal angiomyolipoma (AML) is an uncommon tumor with usual asymptomatic benign evolution. However some enlarging AMLs with ruptured micro-aneurysms can evolve into an abrupt life-threatening situation by the bias of a hypovolemic shock.

 

Case report :

We report a case of 54-year old woman with no medical history admitted to the emergency department with flank pain. On examination, patient was conscious afebrile with respected vital signs: blood pressure = 120/90 mmHg ,regular pulse rate = 77bpm and oxymetry = 99%  on air. The abdomen was soft and painless on palpation. Whereas we noticed left lumbar constriction with a visual pain scale evaluated of 6/10. The diagnosis of left nephritic colic was initially considered and the protocol of analgesia initiated with secondary use of intravenous titrated morphine. Evolution was marked by an abrupt haemodynamic deterioration ( Blood pressure = 60/40 mmHg and tachycardia = 130 bpm)  with useless morphine to release pain. Blood sample arterial gaz showed hyperlactatemia. A computerized abdominal tomography was performed after stabilization and showed a left polar renal angiomyolipoma with ruptured vascular aneurysm complicated by a large retroperitoneal hematoma. Patient was transferred to urology ward for further chirurgical treatement.

Conclusion :

Renal angiomyolipoma is an uncommon usual benign tumor wich is revealed in 10 % of cases by haemorragic shock known as wunderlich’s syndrome. Enlarged AMLs can devolped micro and macro aneurysms that can rupture. Complications are rare but can rapidely evolve to life-threatening  situations especially heamorrhage.


Hamed RYM (Tunis, Tunisia), Maroua MABROUK, Mohamed KILANI, Hana HEDHLI, Abderrahim ACHOURI, Yasmine WALHA, Chokri HAMOUDA
08:30 - 17:40 #11649 - Spontaneous upper limb necrotising myositis: a diagnostic challenge in the emergency department.
Spontaneous upper limb necrotising myositis: a diagnostic challenge in the emergency department.

BACKGROUND

Necrotising soft tissue infections is a life-threatening infection that manifests itself with a sudden onset and rapid spread. There are several predisposing factors and the infection characteristically arises from a skin break or burn.

 

CASE

An 80-year-old male presented with a 1 day history of diarrhoea and vomiting associated with a worsening non-traumatic left arm pain. His past medical history was significant for myelodysplastic syndrome, thrombocytopenia and ischaemic heart disease.

He was haemodynamically stable apart from a temperature of 38.5˚C. Examination of the left upper limb revealed non-tender mild diffuse erythema with a non-pitting oedema and a small blister in the antecubital fossa. There was no neurovascular compromise and he had full range of movement of all joints.

Compartment syndrome was initially considered as patient’s analgesic requirements increased and an X-ray remarkably showed subcutaneous emphysema down the entire length of the left arm.

The patient’s condition rapidly deteriorated with signs of septic shock. The left arm was now more prominently discoloured with multiple blisters ranging from 1-5cm, some of which broke down leaking a clear straw coloured fluid. The diagnosis of necrotising fasciitis became apparent and the patient was aggressively resuscitated with intravenous fluid replacement and antibiotic therapy whilst awaiting surgical debridement. At surgery, the infection was found to have spread to the mediastinum and further intervention was withdrawn. The patient passed away later on.

Clostridium septicum, one of the organisms responsible for clostridium myonecrosis, was identified on microscopy and culture.

 

DISCUSSION

Spontaneous necrotising myositis involving the upper extremities, is a rare form of necrotising soft tissue infection. It can result in fulminant tissue destruction, overt sepsis and carries a high mortality rate ranging from 67-100%.

Clostridium septicum can be found as part of normal gut flora in humans and favours anaerobic conditions. Previous studies have been suggestive of colon cancer being a predisposing risk factor for spontaneous myositis with subsequent myonecrosis. In our case, the final diagnosis was spontaneous upper limb necrotising myositis assumed to be secondary to gut translocation of Clostridium septicum on a background of gastroenteritis and myelodysplastic syndrome.

The problem establishing the diagnosis was the low index of suspicion, if at all, and the rarity of the condition.

Early medical treatment with intravenous broad-spectrum antibiotics should be initiated. Surgical debridement remains the only treatment of choice to prevent further tissues spreading, whilst limb amputation might be indispensable.

 

CONCLUSION

Necrotising myositis of the upper limb is a rare and rapidly progressing soft tissue infection.  Diagnosis of this potentially fatal condition requires prompt investigation and subsequent early surgical intervention to ensure survival.


Sujit KUMARASINGHE, Abdo SATTOUT (Liverpool, UK, United Kingdom)
08:30 - 17:40 #10878 - SPSP deteriorating patient care: 12 months in ED.
SPSP deteriorating patient care: 12 months in ED.

Aim: To assess current quality of care given to the most unwell patients in the emergency department (ED), with focus on those requiring admission to the intensive care unit (ICU) or those dying in the ED. 

Method: In both situations, data from each patient was collected via Trakcare, using a standardised data collection sheet, which included a care quality question, followed by highlighting any potential issues with their care. This was a retrospective data collection by junior staff in the ED and discussed with the lead consultant on a monthly basis. 

Results: In the 12 month period, there were a total of 111 deaths in the ED in RAH. All had their Trakcare death questionnaire filled out. 39 were discussed with the PF, and the remaining 72 deaths had certificates issued, accurate and all cards scanned onto portal.

ICU admissions began to be recorded in the ED from April ’16. In 7 months, there have been 48 admission to ICU in the RAH. Of these, there are still 4 (8.3%) with notes outstanding.

Conclusions: From the data, a number of positive conclusions have been drawn. Primarily, the introduction of Trakcare and the death questionnaire has made a positive impact.There were 4 patients with community DNACPR in place who received CPR or were inappropriately brought to the ED.

With regards to the ICU admissions, the data collected has highlighted a number of positives, as well as potential areas for improvement or change.


Nora GONZALEZ (Paisley, United Kingdom), Chris REID, Struan GRAY, Andrew MERRIMAN, Euan MCMILLAN
08:30 - 17:40 #11686 - Steroid Therapy causing DKA.
Steroid Therapy causing DKA.

Steroid Therapy causing DKA

Introduction: Diabetic Keto Acidosis (DKA) is one of the life threatening conditions among Emergency Department (ED) visits.  Especially DKA in non diabetic young individuals is very difficult to diagnose  at the earliest during initial presentation in ED. Steroid therapy is known to cause rise in blood sugar levels.

Case Description:  32 years old male came to ED with features of Bell’s Palsy and discharged with high dose of oral steroids. He had no pre-existing co-morbidity. On 5th day after discharge, he developed abdominal pain, vomiting, presented to ED with severe dehydration, His blood sugars were 430 mg/dl, ketones 3+ in urine, acetone + in blood,  ABG with Ph 7.13 and bicarbonate of 9 mMol/l, WBC of 14300 with neutrophilic  predominance. He was diagnosed as DKA and treated in ICU with 0.9% Saline IV infusion, Insulin infusion and antibiotics. His HbA1C was within normal limits during hospital stay. After 4 days of hospital stay, he improved and was discharged. After discharge he was closely followed up for the next 6 months, his blood sugars and HbA1C were within normal limits always.

Discussion:  Steroid therapy is an unavoidable cause of hyperglycemia in some conditions such as Bell’s Palsy, Nephrotic Syndrome and Chronic urticaria. In this particular case the patient did not have Diabetes before but still he developed DKA with steroid therapy. There is a risk of life threatening hyperglycemia in patients who are being treated with high dose of steroids for multiple reasons. To avoid this unpleasant side effect before turning into a life threatening condition, close monitor of blood glucose levels in specific intervals will always be of great help.

 

 


Gopikrishna DUVVADA (doha, Qatar), Ramkumar SWAMINATHANE, Suresh THIRUMOORTHY KUMAR
08:30 - 17:40 #11198 - Stevens Johnson’s Syndrome - Unusual history.
Stevens Johnson’s Syndrome - Unusual history.

TITLE OF PAPER

Stevens Johnson’s Syndrome - Unusual history.

 

INTRODUCTION

Stevens Johnson’s Syndrome is a form of erythema multiforme and a variant of toxic epidermal necrolysis. The condition has an approximate incidence of 2 to 7 cases per million people per year. There is no universally accepted criterion to make a diagnosis of Stevens Johnson syndrome/Toxic epidermal necrolysis. Diagnosis at presentation in Emergency Departments is based on history with clinical signs and symptoms. An unusual condition with an unusual history can make the Physicians miss out on a few important pointers for making a diagnosis of Stevens Johnson’s Syndrome.

 

METHODS

We present a case of Stevens Johnson Syndrome with an unusual history.

 

RESULTS

A 56 years old male patient presented with complaints of fever, malaise, sore throat and conjunctivitis.

Symptomatic for two days; whereas conjunctivitis was reasoned with accidentally rubbing fingers into his eyes while cutting chilies the day before.

Examination showed an elevated temperature, inflamed conjunctivae bilaterally, tonsillitis, with oral mucosal ulcerations. However, no skin rash was witnessed. Apart from an elevated CRP, investigations were all normal.

He was referred for Physician’s review with a provisional diagnosis of tonsillitis. Diagnosis was made after ophthalmologist’s report. Patient was intubated on worsening of breathing difficulty along with appearance of lip swelling and skin ulceration. Extubation was done after symptom resolution nearly 5 weeks later.

 

CONCLUSION

Ocular involvement (most commonly severe conjunctivitis) is reported in approximately 80% of Stevens Johnson Syndrome cases. Fever, Malaise and mucosal ulcerations - the common Emergency Department presentations - are non specific.

Whenever an unusual condition presents in an unusual fashion, the differentials must be scrutinized for anything being overseen. This responsibility lies with the Primary treating physicians.

Since a diagnosis still remains sans a universally accepted criterion, Stevens Johnson Syndrome will continue challenging Physicians’ diagnostic skills.


Muneeb SHAHID, Canberk MESELI, Farah MUSTAFA (Drogheda, Ireland)
08:30 - 17:40 #10429 - Strategies to reduce door to needle time for Stroke Telemedicine.
Strategies to reduce door to needle time for Stroke Telemedicine.

Introduction:


Intravenous Recombinant Tissue Plasminogen Activator (rTPA) is an established treatment for Hyperacute stroke. Rapid thrombolysis, or brief “Door to Needle” time is important as it is associated with a significantly improved number needed to treat and there is a lower possibility of intracerebral haemorrhage.

However, Neurology or Stroke specialist physicians are not available 24hours in all hospitals, hence we have developed a telestroke model, Telestroke conferencing has been shown to be cost-effective2.

We have a telestroke model and aimed to reduce thrombolysis time by better management of the processes involved in telestroke services. We have divided the overall process into 4 phases:


    - Phase 1, Door to CT (target 10mins)
    - Phase 2, CT to telestroke registration (target 15mins)
    - Phase 3, Telestroke conferencing registration to approval of rTPA (target 20mins)
    - Phase 4, Approval of rTPA to administration of rTPA (target 15mins)


We conducted an audit of our practice with view to persistent and continual improvement in our processes and “Door to Needle” time.


Methods:


We performed a Retrospective audit of all thrombolysed patients at Khoo Teck Puat Hospital Emergency Department in 2016. The audit studied the average and median times within each discrete phase. Cases which were significant outliers were highlighted and discussed at our stroke workgroup on a regular basis (monthly or bimonthly). Causes of outliers were tackled subsequently, and processes were thus continually improved.


Results for phase 1: On average this phase lasted 13.6mins, median 10.5mins
Results for phase 2: On average this phase lasted 13.4mins, median 11.5mins
Results for phase 3: On average this phase lasted 18.4mins, median 16.5mins
Results for phase 4: On average this phase lasted 21.1mins, median 15mins

This translated to a decrease in overall time to thrombolysis, see attached graph.



Discussion:

We found that stratifying our activities into 4 general component parts helped us to reduce our door to needle time. The inherent delays in telestroke services versus onsite neurology/stroke service need to be mitigated through robust processes. Having stratified our overall process into the 4 main activities involved, we were better able to monitor and manage any delays to thrombolysis.

References

1) BMJ 2014;348:g3429 doi: 10.1136/bmj.g3429 (Published 30 May 2014)

2) Neurology October 25, 2011 vol. 77 no. 17 1590-1598


Sanjay PATEL (Singapore, Singapore), Jasmyn DE LEON, Sok Keng TAN
08:30 - 17:40 #11176 - Stroke In Childhood.
Stroke In Childhood.

INTRODUCTION= Stroke is a focal cerebral damage caused by sudden obstruction or rupture of cerebral arteries or veins, and results in various neurological deficits. Even though it is seen more commonly in adult population, its incidence is 8–10.7/100 000 children/year in childhood. We hereby would like to present a 12-year-old pediatric stroke case who applied to emergency service on foot with superficial complaints.

CASE = A 12-year-old male child was brought to our hospital by his family with the complaints of headache, numbness in the right arm and leg, nausea and vomiting. In his history, the patient who applied on foot, expressed that his complaints started 1.5 hour ago with numbness in the right leg and realized he can’t flex his thigh to abdomen, followed by numbness in the right arm and headache. Moreover, finally vomiting for 2 two times had alerted his family to seek medical help. The physical examination revealed a good general condition, full consciousness and orientation, a Glashow coma scale of 15. Blood pressure was 110/60 mmhg and pulse rate was 86 beats/minutes. There was loss of skeletal muscle strength in the lower right extremity (4/5 ). With stable vital signs on admission, the patient at first underwent a computed cranial tomographic examination which revealed no pathology. Upon a second evaluation a further diffusion-weightedcranial magnetic resonance (MR) examination was decided to perform, which revealed acute restricted diffusion in the posterolateral left cerebral hemisphere. The patient’s neurological deficits were decided due to a cerebral infarction and 0,4mg enoxaparin sodium was administered, followed by transfer to another center because of the absence of pediatric neurology clinic in our hospital. In the referral center, the patient received 0, 4mg subcutaneous enoxaparin sodium treatment twice daily and a complementary physical rehabilitation, which resulted in a complete resolution of the neurological deficits. The genetic examination revealed FACTOR V mutation at nucleotide position at1691. MTHFR (methyltetrahidrofolat reductase) enzyme was found to be heterozygous at nucleotide positions 677 and 1298. Moreover, PAI gene analysis demonstrated heterozygous positivity.

RESULT=Cerebrovascular diseases, albeit very rare, can be encountered in pediatric age group. Since these patients might be admitted to emergency departments with relatively faint complaints rather than an ultimate hemiplegia, a more meticulous neurological examination should be performed in pediatric age groups, placing more emphasize on relatively faint complaints and we should not hesitate to carry out further examinations like diffusion-weighted cranial MR. 


Hacı Mehmet ÇALIŞKAN, Burak ÇELIK (İstanbul, Turkey), Süleyman ERSOY
08:30 - 17:40 #10493 - Structure rupture: a deadly surprise.
Structure rupture: a deadly surprise.

Objectives: We describe a novel case presenting to the Emergency Department with some interesting learning points.

Case Presentation: An 86 year old with vascular dementia presented to the Emergency Department with generalised abdominal pain radiating to the back with associated dyspnoea, pallor and diaphoresis. She denied nausea and vomiting and had not undergone any recent instrumentation. On examination, she was haemodynamically stable with new onset atrial fibrillation and a tender abdomen throughout. Her aorta measured 2.4cm on bedside ultrasound and family members, upon arriving at the hospital, reported a change in the patients’ voice. 

Results: The working diagnosis was ischaemic bowel vs. aortic dissection and thus, an abdominal CT was requested. Chest radiography was performed prior to the CT which showed unexpected extensive surgical emphysema which was not apparent on physical examination. A CT thorax was  thus performed revealing extensive pneumomediastinum and a distal oesophageal rupture. Unfortunately, the patient was not a candidate for surgical repair and passed away.

Conclusion: Spontaneous oesophageal rupture is a rare, but important, cause of acute abdominal pain. In this case, the occurrence in the absence of vomiting or trauma was identified following a change in the patients' voice the incidental discovery of surgical emphysema on a routine chest radiograph, which prompted further imaging of the thorax. Thus, chest radiography is a cheap, simple and easily accessible investigation that can prove invaluable in the diagnosis of spontaneous oesophageal rupture and would guide the need for a computed tomography scan of the thorax to also be performed.

Learning Points:

•Spontaneous oesophageal rupture is a rare, but important, cause of abdominal pain.
•Symptoms of oesophageal rupture can be highly variable and the condition can occur even in the absence of a history of vomiting or recent instrumentation.
•Chest radiography is a cheap, simple and easily accessible investigation that can prove invaluable in the diagnosis of spontaneous oesophageal rupture and would guide the need for a CT thorax.
A change in the voice of a patient may prove to be an important diagnostic clue to investigate the chest more closely.

Sarah WINFIELD (Liverpool, United Kingdom), Rehman RAJ
08:30 - 17:40 #10942 - Subgroup analysis of the extended efficacy and safety of low-dose methoxyflurane analgesia in adult patients from the STOP! study with acute pain due to fractures, dislocations and other injuries.
Subgroup analysis of the extended efficacy and safety of low-dose methoxyflurane analgesia in adult patients from the STOP! study with acute pain due to fractures, dislocations and other injuries.

Background

STOP!1,2 a randomised, double-blind, placebo-controlled UK study of low-dose methoxyflurane analgesia in 300 patients ≥12 years presenting to the ED with acute pain due to minor trauma. We present a post hoc analysis of pain relief beyond 20 min after the start of treatment, inhaler use and safety in two subgroups from STOP!: adults with dislocations/fractures, and adults with ‘other’ injuries (mainly sprains, soft tissue injury and muscular pain).

 

Methods

Patients were randomised 1:1 to methoxyflurane (3mL) or placebo (normal saline), self-administered via a Penthrox® inhaler. Patients could cover the diluter hole in the mouthpiece to inhale a higher concentration of study medication. A second inhaler and/or rescue medication were provided if requested. Visual analogue scale (VAS) pain intensity was assessed at 5, 10, 15, 20 and 30 min, then every 30 min until discharge (data are presented for time points where n≥2). Adverse events (AEs) were recorded from enrolment until discharge, and at safety follow-up (Day 14±2).

 

Results

The dislocation/fracture subgroup included 21 males and 18 females, mean age 37 years (N=36 for fractures and N=3 for dislocations). Mean decreases in VAS pain intensity of ‑41.3, -41.5, -56.0 and -47.0mm (from a baseline mean of 67.5mm) were observed with methoxyflurane at 20, 30, 60 and 90 min. Mean decreases of ‑24.0, -22.2 and -40.5mm (from a baseline mean of 67.3mm) were observed with placebo at 20, 30 and 60 min. 35.0% of methoxyflurane patients and 21.1% of placebo patients requested a second inhaler, after a median time of 50.0 and 59.0 min, respectively. 30.0% of methoxyflurane patients and 42.1% of placebo patients covered the diluter hole. 

 

The ‘other’ injury subgroup included 56 males and 52 females, mean age 36 years. Mean decreases in VAS pain intensity of -29.8, -35.4, -26.1 and ‑35.6mm (from baseline mean of 64.3mm) were observed with methoxyflurane at 20, 30, 60 and 90 min. Mean decreases of ‑14.5, -14.5 and -19.8mm (from baseline mean of 66.3mm) were observed with placebo at 20, 30 and 60 min. 18.9% of methoxyflurane patients and 10.9% of placebo patients requested a second inhaler, after a median time of 53.5 and 41.5 min, respectively. 35.8% of methoxyflurane patients and 47.3% of placebo patients covered the diluter hole.

 

AEs (mostly mild, transient dizziness/headache) were reported by 35% of methoxyflurane and 37% of placebo patients in the dislocation/fracture subgroup, and 68% of methoxyflurane and 46% of placebo patients in the ‘other’ injury subgroup; none caused withdrawal.

 

Conclusions

The results show the reduction in pain intensity with low-dose methoxyflurane analgesia is maintained for the duration of use in adult patients with fractures, dislocations and other minor trauma injuries.

 

References

  1. Coffey F et al. Emerg Med J 2014;31:613-8.
  2. Coffey F et al. Adv Ther 2016;33:2012-31.

 

Acknowledgements

Study sponsor:Medical Developments International(MDI)

®PENTHROX is a registered trademark of MDI.


Patrick DISSMANN (Detmold, Germany), Frank COFFEY, Kazim MIRZA, Mark LOMAX
08:30 - 17:40 #11885 - Success rate of pneumatic reduction of intussusception with and without sedation.
Success rate of pneumatic reduction of intussusception with and without sedation.

Background: Pneumatic reduction of ileocolic intussusception is often performed without sedation. The aim of this study was to evaluate the success rate of pneumatic reduction of intussusception with and without sedation.

Methods: We conducted a retrospective cohort study in Israel in two tertiary care centers using a similar protocol for pneumatic reduction of intussusception. In one center, patients had pneumatic reduction of intussusception under propofol-based sedation, while in the other, patients had pneumatic reduction of intussusception without any sedation. We included Children aged 3 months to 8 years who were diagnosed with ileocolic intussusception between January 1, 2008 and July 31, 2015. Primary outcome measure was adjusted odds ratio for reduction success. We used multivariable regression to account for possible confounders (age, gender, number of cases of intussusception prior to the study period, time period from the beginning of symptoms to emergency department admission (<12 h, >12 h), and time period from emergency department admission to the beginning of pneumatic reduction of intussusception). Secondary outcome measures were the proportion of bowel perforations during the procedure, and the proportion of early (within 48 h) recurrence of intussusception.

Results: 124 and 90 patients were included in the sedation and non-sedation cohorts. The demographics, time variables (symptoms duration and time from ED admission to procedure) and clinical variables (vital signs, blood gases test results) were comparable between both groups. Success rate of pneumatic reduction were 89.5% and 83.3% for the sedation group and non-sedation group, respectively, with adjusted odds ratio of 1.2, 95% CI 1.1-5.3.  Bowel perforations occurred in 0 non-sedated patients and 3 sedated patients. All perforation cases occurred in young infants (<6 months of age) with symptoms duration > 12h. Rates of early recurrence of intussusception of sedated patients and non-sedated patients were 5.1% (6/117) and 1.3% (1/79), respectively (P = 0.15, RR = 3.9, 95% CI: 0.47 to 31.81). None of the sedated children required intubation or PICU admission due to sedation related adverse events.

Conclusions: The findings suggest that the pneumatic reduction of intussusception under propofol-based sedation had a slightly higher success rate than the pneumatic reduction of intussusception without sedation. Although the rate of bowel perforation and early recurrence didn’t differ significantly, the safety of this practice should be evaluated in further studies. 


Ori DEVIR, Oren FELDMAN (Ramat Gan, Israel), Giora WEISER, Uri BALLA, Eran KOZER, Itai SHAVIT
08:30 - 17:40 #11754 - Successful use of extracorporeal membrane oxygenation in a patient with silicone embolism: case report.
Successful use of extracorporeal membrane oxygenation in a patient with silicone embolism: case report.

Introduction: Silicone embolism (SE) is dependent on a high clinical suspicion based on refractory respiratory insufficiency, cutaneous petechiae, and cognitive dysfunction which develop in the first few days. SE is associated with a high mortality due to acute right ventricular failure and hypoxia. Extracorporeal membrane oxygenation (ECMO) has shown to be life-saving procedure in patients with respiratory failure and high probability of death with conventional treatment. Herein, we describe the successful use of veno-arterial (V-A) ECMO in patient with silicone embolism.

Case presentation: A 65-year-old woman was admitted to Emergency department (ED) with burning sensation of the left eye and edema of upper left eyelid. Shortly after admission she developed left sided numbness and progressive global respiratory insufficiency. She was intubated and mechanically ventilated. Emergency echocardiography (ECHO) revealed dilated right ventricule and pulmonary hypertension, perserved left ventricule function, with extensive echo contrast in the left atrium and ventricule of unknown origin. Multislice computed tomography (MSCT) pulmonary angiography, aortography and brain angiography were unremarkable. Past medical history revealed that, 3 years earlier, the patient had undergone gamma-knife and endoresection with instilation of silicone oil because of left eye melanoma. As well, one year earlier, she was treated in an other hospital for acute respiratory insufficiency with signs of cor pulmonale on the ECHO, and multiple ground-glass opac ities on the lung MSCT. At the time she fully recovered.

While in ED, despite maximal ventilatory support, oxygen saturation deteriorated and blood gas analysis showed even more profund acidosis, without hemodynamic instability. Decision of implementing periferal V-A ECMO was then made. While preparating for ECMO, the patient developed pulseless electrical activity therefore resuscitation was carried out following two adrenaline boluses. ECMO circulation was succesusfully placed and return of spontaneous circulation occured. Finally, respiratory function was stabilised. The next day patient developed petechial hemorrhages. Bearing in mind the initial presentation, past history of silicone oil use and the echo-contrast of unknown origin, these findings were suggestive for silicone emoblism. In the following days, the patient developed motoric weakness of all extremities. Control brain MSCT confirmed ischemic lesion in the right frontal lobe and left parietal lobe, both without signs of haemorrhage. Five days later, V-A ECMO was discontinued and the patient showed clinical improvement.

Conclusion: Veno-arterial ECMO is highly invasive and associated with numerous potential complications. However, for some patients who don´t respond to all traditional resuscitative strategies, it could be a life-saving method bypassing pulmonary involment of the circulation. As shown in our case report, ECMO can be a bridge to recovery.


Lea MIKLIC (Zagreb, Croatia), Tena TRBOJEVIC, Ivan GORNIK
08:30 - 17:40 #11335 - Sudden drop.
Sudden drop.

45-year-old Woman with no relevant medical history arrives at the Emergency Department complaining of epigastric and left flank abdominal pain. The pain began less than twenty-four hours ago and has increased in intensity interfering with nocturnal rest. She denies any other symptomatology. 

On physical examination, the patient is alert and lucid. She is afebrile and presents cutaneous pallor. Blood pressure 120/80 mmHg with a heart rate of 100 bpm. She seems eupneic, with basal Sat O2 99%. On abdominal palpation, she refers diffuse abdominal tenderness mostly located in the umbilical region but no signs of abdominal guarding. 

Analytics shows Hemoglobin 8.1 g/dl, 23700 Leukocytes with 20500 PMNn. The rest is under normal limits. 

Given the wellbeing of the patient, we request an urgent ultrasound. The radiologist alerts about a sudden deterioration of the patient, who presents plenty of abdominal fluid suggestive of hemoperitoneum. The radiologist is unable to find out where the bleeding comes from using the ultrasound. 

The patient is immediately transferred to the resuscitation room while ICU team and General Surgeons are alerted, proceeding to stabilization of the patient, orotracheal intubation, and urgent laparotomy.  

A central retroperitoneal hematoma with two litters of hemoperitoneum is found but the bleeding spot is not visualized. After aortic clamping above celiac artery and clipping of splenic artery, the bleeding ceases. A splenectomy is performed after evidencing a spleen rupture. 

Clinical diagnosis: massive hemoperitoneum due to spontaneous splenic rupture.

After one month admitted in the Hospital, with complications that interned her into the ICU, the patient was discharged and followed up in General Surgery external consult. 

Conclusions: 

Spontaneous rupture of the spleen is a rare entity, of which there are few cases described in the medical literature. The etiopathogenic mechanism is unknown. It is more frequent and can occur in all those pathologies with splenomegaly associated.  

It should be suspected in those patients with epigastric pain and pain in the left hypochondriac region, radiated to the scapula and left shoulder who develop sudden hypovolemic shock. Abdominal ultrasound is very sensitive and is the first test to be performed. However, the abdominal CT is the method of choice, since it allows to visualize the type and magnitude of the splenic lesion. Splenectomy is the treatment of choice.


Isabel FERNÁNDEZ-MARÍN (Madrid, Spain), Víctor SÁNCHEZ ALEMANY, Ana Belén CARLAVILLA MARTINEZ, Carlos RUBIO CHACON, María Lorena CASTRO ARIAS, Susana BORRUEL NACENTA, Luis YUBERO SALGADO
08:30 - 17:40 #11394 - Sudden onset head and neck pain: Vertebral artery dissection. A case report.
Sudden onset head and neck pain: Vertebral artery dissection. A case report.

Background: Strokes due to cerebral artery dissection is a common condition in young adult patients but may occur at any age. The incidence of such dissections is 2.6 in 100000, whereas the ratio in dissection of vertebral arteries is less than 1 in 100000.

Case: A thirty-one-year-old man was admitted to the emergency department with severe head and neck pain that started suddenly the night before and dizziness, weakness in the right arm and leg, and syncope in the morning hours. He did not have any chronic disease, drug use or trauma history. At the time of presentation, his vitals noted as fever: 36.7 ºC, pulse rate:102/min, respiration rate:24/min and BP: 180/110 mmHg. His general appearance was severe, he was sleepy but showing occasional agitation attacks with no orientation and no co-operation, IR + /+, Pupils were isochoric, eyes were left-fixed. Nuchal stiffness was absent and his GCS was 12. Brain CT showed no hemorrhage, whereas Brain angio CT revealed a compatible appearance with dissection in the left vertebral artery. Diffusion Brain MR also showed diffusion restriction in the left cerebellar hemisphere (Figure 1,2). The patient was hospitalized and followed up in the intensive care unit.

Discussion: Vertebral artery dissection (VAD) generally occurs as a result of trauma involving some degree of cervical distortion although it may occur spontaneously as well. Connective tissue diseases such as Marfan or Ehler-Danlos syndrome, fibromuscular dysplasia, cystic medial necrosis, hypertension, smoking and oral contraceptive use may also be associated with vertebral artery dissections. The clinical picture often begins with a sudden, severe craniocervical localized headache, and then signs related to ischemic changes of the brain stem are added. CT or MR angiography is usually adequate for diagnosis and for vessel cerebral angiography is not needed generally. The most frequent radiologic findings are vertebral artery stenosis, string of pearls sign, arterial dilatation and occlusion, pseudoaneurysm, double lumen finding, intimal wing sign. Narrowing of a long segment of the artery, which is thought to be characteristic of dissection, is referred to as the “string sign” or, when there is focal narrowing with a distal site of dilatation, as the string of pearls sign. These two characteristic signs demonstrate dynamic changes at follow-up angiography, that is, resolution of the stenosis or progression to complete occlusion. Anticoagulation therapy is used for treatment in cases who don’t have any accompanying bleeding or intracranial dissection and any other contraindication. The prognosis in early diagnosed cases is more satisfying.

Conclusion: VAD is one of the common causes of ischemic stroke in young patients and should be remembered in patients with acute onset of headache and neck pain with neurological deficit in emergency departments.


Oğuz EROĞLU, Sinan Oğuzhan ÖZHAN, Ertan CÖMERTPAY, Sevilay VURAL, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #11221 - Sudden pain relief in acute renal colic : what should we suspect?
Sudden pain relief in acute renal colic : what should we suspect?

Introduction

Spontaneous rupture of the upper urinary tract is a rare event. It may be life threatening situation if not diagnosed rapidly. In this topic, we report the case of a patient presenting to the emergency department (ED) with severe pain due to renal colic and sudden pain relief.

 

Observation

A 47-year-old man with no medical history presented to the ED complaining of rapid onset of severe left flank pain with macroscopic haematuria. The physical exam was difficult because of the intensity of the pain. Analgesia was started with acetaminophen and non-steroid anti-inflammatory. Intravenous morphine titration was prescribed at an increasing dose. A sudden pain relief was observed and the patient felt better. The visual analogue scale decreased from 85 mm to 22 mm in two minutes.

Ultrasonography was performed promptly and showed left perirenal fluid with ureterohydronephrosis related to an upper ureteral rupture.

The patient was transferred to the urology department and a left percutaneous nephrostomy was performed.

 

Conclusion

Sudden and rapid pain relief during the management of acute renal colic may reveal a severe complication: rupture of upper urinary tract. Monitoring of pain levels is important to consider.


Ines CHERMITI, Hanène GHAZALI (Ben Arous, Tunisia), Anware YAHMADI, Rihab DIMASSI, Siwar JERBI, Najla EL HANI, Monia NGACH, Sami SOUISSI
08:30 - 17:40 #11816 - Superficial venous thrombosis. More important than it seems.
Superficial venous thrombosis. More important than it seems.

Background:

Venous thromboembolism (VTE)  is a common problem seen in the emergency department (ED).For the associated implications, an early and acute diagnosis is necessary.Superfical venous thrombosis (SVT) has received increased attetntion as more physicians are recognizing the potential morbidity of untreated disease. We are faced with the problem that sometimes SVT is more extensive than physical examination suggest with the added risk involved. The degree and extent of thrombosis in patients with SVT are characteristically underestimated and such patients have coexistence of,and/ot rapid progression to systemic venous thromboembolism.

Patient & method:

We present the case of a 72 year old female with no medical history of interest  with pain and localized redness in midle thigh without signs of proximal extension in physical examination.No dyspnea.No paralysis or inmovilization, no active cancer, no collateral circulation, no leg swollen and no other symptoms. (low risk DVT).
After bedside ultrasound we found a thrombous in the saphenous vein in midle thigh that extends proximally over than 15 centimeters to a common femoral vein.

Conclusion:

Beside ultrasound provides a readily available, rapid non invasive imaging modality that complement clinical evaluation.The utility of bedside ultrasound has been proven for multiple purposes but is not yet completely integrated in the physical examination of patientes in the ED. It provides rapid and real time information who allow us  the accute diagnosis of  pathologies as SVT and assist in patient care, clinical decisions and also provides ED efficiency. In patients with SVT beside ultrasound  exploration of the venous system of the affected limb is very useful because it provides information to guide management. The exploration should not be limited to the superficial venous system and should be extended to the  proximal deep venous system of the affected leg.


Jaldún CHEHAYEB MORÁN (Valladolid, Spain), Carlos DEL POZO VEGAS, Marina Isabel REVILLA MARTÍNEZ, Marta CELORRIO SAN MIGUEL, Armen HAMBARDZUMYAN, Enrique Antonio SERRANO LACOUTURE, Susana DE FRANCISCO ANDRES, José Vicente ESTEBAN VELASCO, Sonia DEL AMO DIEGO, German FERNÁNDEZ BAYÓN
08:30 - 17:40 #10972 - Surprise, it's a baby.
Surprise, it's a baby.

•Personal history:

A 21-year-old woman with no previous history of interest, comes to the emergency room for intermittent abdominal pain of about 2 hours of evolution, which is becoming more intense and frequent. They were having lunch with the family, but the intense pain makes them go to the emergency room. Now, she is asymptomatic.

Deny urinary clinic. Does not present changes in bowel habit.

Deny gestation. She refers to presenting her menstruations with variability in intensity and duration (sometimes 1 day another 3-4 days, less intense than usual). She indicates its existence every month, although she does not know precise dates. Relates the irregularity with the use of emergency contraception with a postcoital pill on 3 occasions in the last 6-7 months.

Deny has a fever. No other referred clinic.

• Exploration:

TA 115/75. FC 98 bpm. FR 10 RPM. Temperature 36.7 ° C. Thin. Conscious and oriented. Good general condition. Well moisturized and perfused.

ACR: Regular rhythmic tones around 95 bpm without blows. Vesicular murmur preserved without added sounds.

Abdomen distended, with skin to tension, impresses of advanced gestation although it is not very voluminous, even palpates mass of at least 40 cms and with mobility, compatible with baby so it is re-interrogated to the patient on the possibility of pregnancy but she continues to deny it.

•Evolution:

However, by high suspicion of advanced pregnancy, Gynecology is contacted on guard, which, after initial evaluation and presentation of birthing dynamics, goes into the parlor, producing a natural baby birth to term in just 30 minutes (weight 2.750 gr, Test Apgar at the born 9).

• Conclusions:

Clinical history is a fundamental process in medicine, although on many occasions due to lack of knowledge of the patient, inability to report the facts or expressly not to indicate the truth, can be altered and difficult diagnosis even in very evident.


David NUÑEZ CASTILLO (SPAIN, Spain), Pilar VALVERDE VALLEJO, Jorge PALACIOS CASTILLO
08:30 - 17:40 #11905 - Survey of psychiatric disorders (axis I) in traumatic patients referred to trauma centers related to Iran University of Medical Sciences, 2014.
Survey of psychiatric disorders (axis I) in traumatic patients referred to trauma centers related to Iran University of Medical Sciences, 2014.

Introduction: Traumatic injuries are the most common cause of Emergency Department visits. According to previuos studies near to 36% of ED visits are belong to trauma. There are several studies about post traumatic psychiatric disorders but to our knowledge there is not any study about association between psychiatric disorders and occurance of trauma.

Materials and Methods: This observational cross-sectional study was performed in three trauma centers related to Iran University of Medical Sciences. The statistical population were trauma patients who were victims of motor vehicle collisions. Sample size was 90 trauma patients and we matched 90 healthy volunteers to compare psychiatric disorders. SCID questionarrie was applied in order to find disorders.

Results: Anxiety disorder, bipolar disorders (B II D), alcohol and drug dependence were more common in trauma victims whereas obsessive-compulsive disorder were significantly higher in healthy volunteers.

Conclusion: Considering the high prevalence of psychiatric disorders in trauma patients, we recommend that before confirming lisence of driving all candidate undego screening interview and who suffered from major mood disorders refer to psychologist. It process can decrease motor vehicle crashes. 


Rezai MAHDI, Dr Neda ASHAYERI (Tehran, Islamic Republic of Iran), Reza MOSADEGH
08:30 - 17:40 #11038 - Survival of symptomatic or ruptured abdominal aortic aneurysms in an Emergency Department (Open vs Endovascular Repair).
Survival of symptomatic or ruptured abdominal aortic aneurysms in an Emergency Department (Open vs Endovascular Repair).

Introduction:

Abdominal aortic aneurysm (AAA) is a life-threatening condition in Emergency Departments. In addition to an early diagnosis, it is important to determine which surgical treatment is most effective in each patient (Open versus Endovascular repair) in an effort to reduce the morbidity and mortality of these patients.

We analyse the results in our center since the implementation of a new protocol of emergent endovascular repair in ruptured or symptomatic AAA.

 

Patients and Methods:

We retrospectively analyzed all consecutive patients with symptomatic or ruptured AAA treated from 25/06/2015 to 25/11/2016.

Demographic and clinical data were collected from each patient, as well as type of treatment and in-hospital mortality.

 

Results:

During the period of study, 18 patients were admited at our center, 6 with the diagnosis of symptomatic AAA and 12 with ruptured AAA. All of them were male with a mean age 80,1 years. Cardiovascular risk factors were high blood pressure (84,5%); ischemic heart disease (47%); dyslipemia (37%); chronic obstructive pulmonary disease (32%); and diabetes mellitus (16%).

3 patients were not treated (2 because of impossibility to treat and 1 because of pre-operative death). 5 patients underwent open surgery and 10 underwent endovascular repair. Global mortality rate was 13,3%. It is important to point out that mortality under open repair was 40% whereas with endovascular repair it was 0%.

 

Conclusions:

Survival of patients with symptomatic or ruptured AAA treated with endovascular repair is greater than with open surgery (100% vs. 60%). In our center, endovascular repair has become the first treatment option as long as the anatomy of the aneurysm allows it.

This work is limited by the low number of patients. Prospective studies with larger number of patients must be carried out in order to confirm these results.

 

 


Jaime FONTANALS, Angel CABALLERO (Barcelona, Spain), Marta MAGALDI, Julia MARTINEZ-OCÓN, Ana RUIZ, María José CARRETERO, Purificación MATUTE
08:30 - 17:40 #11868 - Sweet pussycat.
Sweet pussycat.

- Reason for referral: Pruritus both eyes, fever and preauricular adenopathy.

- Previous medical history: No known drug allergies. Pathological antecedents for Lyme disease in 2014.

- Patient profile: A 32-year-old woman was derived from Ophthalmology by preauricular adenopathy, which had increased in size in relation to papillary conjunctivitis. This conjunctivitis was still present after a month of evolution, without improvement with symptomatic treatment. This day the patient was derived to the emergency room by general discomfort, low-grade fever, systemic clinic, in treatment with ibuprofen without improvement. No cough or expectoration, no odynophagia, no abdominal pain

-  Physical examination:

Conscious and oriented, isocoric and normoreactive pupils. Cranial pairs without alterations. No epidermal lesions. Normal cardiac auscultation. Preserved vesicular murmur. Abdomen without alterations. Preauricular painful adenopathy extending to the mandibular arch. Edema and erythema upper eyelid. Hyperemic pharynx.

- Routine investigations:

            + ECG: Normal

            + Chest X ray: Normal

            + Blood count: Normal. Basic biochemistry: Normal. Coagulation: Normal. ESR: 24 mm/hr. Urinalysis: Normal. Serologies of hepatitis, HIV, syphilis, Rickettsia Conorii, Bartonella Henselae.

- Evolution: In the following days, we had the results of the serologies. All were normal except for IgG Bartonella Henselae (1/512), which indicated recent infection, IgM Bartonella negative, IgG Rickettsia conorii positive (1/160), IgM Rickettsia conorii negative. The patient said to us that she had a cat. It had scratched the patient two months ago.- Diagnostic orientation: Cat scratch disease.

- Treatment: We prescribed doxycycline as a treatment, 100 mg each 12 hours during 14 days, and Ketotifen 1 drop twice daily for 15 days and dexamethasone with gentamicin 1 drop 3 times a day for 5 days.

- Evolution after the treatment: The patient improved of the symptomatology.


Juan Ortega Pérez, MERITXELL VIDAL BORRÀS, ELISA ALBACAR RIBA, (Palma de Mallorca, Spain)
08:30 - 17:40 #11121 - Syncope as presentation of Lymphoma.
Syncope as presentation of Lymphoma.

Objetive: To recognize atypical symptomatology for diagnosis of lymphoma

 Method: Patient of18 years without relevant medical history consulting for vasovagal syncope. Several previous simlares episodes. important job stress, fatigue and catarrhal syndrome. No toxics. Physical examination nondescript except scratching lesions in extremities due to pruritus for months. Radiography of chest demonstrating large mass in the left hemithorax in relation to mediastinal widening anterosuperiror makes rim silhouette with heart and windpipe moves to the right is performed. In blood test:  leukocytosis. Tac thoraco-abdominal lymphadenopathy and bilateral supraclavicular large mediastinal mass that includes left and imprint superaaorticos trunks and main bronchus. Embryogenic tumor suspected.

 Results: After hospitalization and specific studies is diagnoses of Hodgkin's disease nodular sclerosis type IIB with Bulky mediastinal mass. Syncope would be in relation to low spending by compression of vessels.

 Discusion: Hodgkin's lymphoma is a highly curable disease; however, atypical presentations may mimic other diseases. Often there are no clues from history, physical examination, or imaging studies to differentiate Hodgkin's lymphoma from other diseases causing mediastnal masses. Moreover, histological workup by CT-guided core needle biopsy may be nondiagnostic. Therefore, it is important to be vigilant in pursuing further workup if an initial biopsy of a mediastinal mass only reveals granulomatous change


Rocio BORDALLO ARAGON, Ana PEREZ TORNERO, Rocio RODRIGUEZ BARRIOS (MALAGA, Spain)
08:30 - 17:40 #11381 - Syncope patients admitted to the emergency department with normal electrocardiogram.
Syncope patients admitted to the emergency department with normal electrocardiogram.

Introduction

Syncope is a challenging presentation for the emergency physician. Various clinical risk scores and clinical decision rules are designed to identify the population at highest risk for adverse events especially cardio-vascular causes. The electrocardiogram (ECG) is one of the most important key clinical variables used to evaluate the patient and decide whether hospitalization is required or ambulatory management is safe.

The aim of our study was to evaluate patients admitted to the emergency department (ED) for syncope with normal initial ECG.

 

Methods

Prospective observational study over three years. Inclusion of adult patients admitted to the ED for syncope with normal initial ECG. Interpretation of ECG was performed separately by two senior doctors.  Analysis of demographic and clinical characteristics. EGSYS score was calculated for all patients. Follow-up over one year.

 

Results

Inclusion of 138 patients. Mean age 46 ± 18 years. Eighty percents (n=110) of patients were aged less than 60 years. Sex-ratio=1.6. Comorbidities n(%): hypertension 35(25) and hypertension 24(17). EGSYS score ≥ 3 was observed in 37 patients (27%). Early discharge was decided in 76 patients (55%). Causes n(%): Reflex 51(37), orthostatic hypotension 23(17), cardiac cause 19(14) and unexplained 45(33). Ten patients (7%) had a new episode of syncope during follow-up and three died (2%).

Conclusion

Usually, absence of ECG abnormalities during the evaluation of syncope patients is reassuring the ED physician. The ECG, even if normal, should be integrated in decision making algorithms. Our study demonstrated that 14% of patients with normal ECG at admission had cardiac causes of syncope.


Hanène GHAZALI, Ines CHERMITI (Ben Arous, Tunisia), Morsi ELLOUZ, Anware YAHMADI, Ahlem AZOUZI, Mohamed MGUIDICHE, Siwar JERBI, Sami SOUISSI
08:30 - 17:40 #11208 - Tackling the death squad: major trauma after medical cardiac arrest.
Tackling the death squad: major trauma after medical cardiac arrest.

Case 1

A 75-year old male suffered a witnessed out-of-hospital cardiac arrest (OHCA) whilst cycling. Bystander cardiopulmonary resuscitation (CPR) was started and Advanced Life Support was continued by the Emergency Medical Services (EMS). After 20 minutes of CPR, the patient had return of spontaneous circulation (ROSC). As the initial electrocardiogram (ECG) showed an inferolateral ST-elevation myocardial infarction (STEMI) and non-sustained ventricular tachycardia (VT), heparin and acetylsalicylic acid were administered. A CT-scan showed a subarachnoidal haemorrhage, a left sided haemopneumothorax, flail chest due to multiple rib fractures and active haemorrhage of the left kidney and the left deep femoral artery. A balloon angioplasty without stenting of the left descending artery was performed, as stenting would require antiplatelet therapy. During the procedure, a thoracostomy was performed for the haemopneumothorax. Massive transfusion was initiated at the end of this procedure due to increasing haemodynamic instability. Subsequently, angiographic coiling of the kidney, intercostal arteries and deep femoral artery was performed. The patient died two weeks later due to post-anoxic encephalopathy.  

Case 2

A 67-year old male was involved in a frontal collision whilst driving his car. As he was in cardiac arrest, bystander CPR was initiated which was continued by the EMS. The patient had ROSC after 45 minutes. The ECG showed no ST-wave abnormalities. CT-scan showed multiple rib fractures and blood around the liver and spleen. The patient was transferred to the intensive care unit without surgery as he remained hemodynamically stable. A coronary angiography was performed one week later diagnosing 3-vessel disease after previous coronary artery bypass graft. A bare metal stent was placed in the right coronary artery.  The patient was discharged after 3 weeks and was neurologically intact.

Discussion

As elderly people remain more active, the chances of a medical cardiac arrest leading to trauma increases. In patients with OHCA with associated major trauma the possibility of a cardiac cause of the arrest should therefore always be considered. Antiplatelet therapy should not be given prehospitally, even if a STEMI is present, as traumatic coagulopathy is the most important cause of death in major trauma. If a medical cardiac arrest is suspected, a cardiologist should be included in the trauma team to enable early multidisciplinary management. Whenever possible, a CT scan should be performed before coronarography as this adds valuable information whilst deciding about the therapy. In the first patient, a coronarography was performed because of ST elevation and non-sustained VT. In the second case, an elective coronarography was performed because of a non-STEMI. Anticoagulation therapy was started after admission at the intensive care unit. If no coronarography is performed, serial troponin level measurement and the ECG should be monitored continuously.


Michiel D'HONDT (Antwerp, Belgium), Philip VERDONCK, Koen MONSIEURS
08:30 - 17:40 #11476 - Tako-tsubo Cardiomyopathy in a Patient with nephritic colic:.
Tako-tsubo Cardiomyopathy in a Patient with nephritic colic:.

Introduction :

Tako-tsubo cardiomyopathy (TTC) is an important differential diagnosis of acute coronary occlusive myocardial infarction that should be understood by all clinicians Although TTC is frequently clinically indistinguishable from acute coronary syndrome; it is readily differentiated with coronary angiography. TTC is frequently precipitated by physical or emotional stress, and after an acute phase during which the patient may be significantly haemodynamically compromised, there is rapid recovery and an excellent prognosis. We report a case of clinical presentation of acute coronary syndrome whose path physiological mechanism is not or not mainly due to atherosclerotic lesions.

Case Report : 

This is a 48-year-old patient who initially consults our emergencies for right flank pain that had lasted for weeks but became exacerbated in the previous few hours. He was treated as renal colic. The patient received analgesic treatment without improvement. The patient presented secondary a continuous chest pain and dyspnea . The electrocardiograms showed a lateral and inferior myocardial infarction. The anti-ischemic treatment was administered. The coronary angioplasty was normal. The patient was hospitalized in Invasive Cardiology Department. Blood examination revealed elevated cardiac enzymes: troponin I 4.57ng/mL (normal < 0.05 ng/mL).The echocardiography returned normal. Cardiac magnetic resonance imaging (CMRI) was normal. The patient still retains pain in the right flank, with Hematuria. An uroscanner was performed and showed an obstructive lumbar ureteral lithiasis. The patient was hospitalized in urology department and an ureteroscopy was performed. His symptoms relieved spontaneously without returning. The diagnostic of Tako-tsubo cardiomyopathie due to an acute and intense pain was made.

Conclusion :

Takotsubo cardiomyopathy (TCM) is a unique type of cardiomyopathy characterized by left ventricular systolic dysfunction in association with stressful conditions. Patients with this condition usually present with chest pain and dyspnea , and the presentation can mimic acute coronary syndrome.


Ines GUERBOUJ, Rim HAMAMI (Tunis, Tunisia), Olfa DJEBBI, Mehdi BELLASSOUED, Mounir HAGUI, Ghofrane BEN JRAD, Khaled LAMINE
08:30 - 17:40 #11914 - Takotsubo syndrome.
Takotsubo syndrome.

The late dinner turned into fight for life of three people. A man chocking resulted into asphyxia, cyanosis, loss of consciousness and gasping. Gordon maneuver was successful and the patient has had no consequences. After this stressful event, wife and neighbour (postmenopausal women with cardiac disorders) were feeling chest pain. They were given first aid according current recommendations. Wife of the chocking man was transported to the hospital as unspecified angina pectoris. Neighbour was left home despite ECG showing acute coronary syndrome. EP on the scene described ECG as physiological and recommended sedatives. However, she sought out help after the pain had been persisting whole night. In the morning, she was transferred by husband to a doctor who, according to ECG (nonspecific changes in the repolarization) and elevated serum troponin (137,1 ng/L) confirmed acute coronary syndrome. She was hospitalized 8 days in ICU next to the wife of the chocking man. Neighbour was discharged home as Takotsubo Cardiomyopathy in acute stage with ejection fraction of 25%. She remained home for next 6 months. Takotsubo Cardiomyopathy, also known as broken-heart syndrome, occurs after sudden heavy stressful situation mostly in postmenopausal women. Rare syndrome is expected to be caused by catecholamines. The damage of left ventricle is reversible within 4 – 6 weeks. Incidence is 1 – 2 % of patients with ACS symptoms. In pre-hospital settings it is not distinguishable from ACS.

kadlecik2@gmail.com


Jozef KADLEČÍK, Dobiáš VILIAM (Bratislava, Slovakia), Alena DUDEKOVÁ, Táňa BULÍKOVÁ
08:30 - 17:40 #11201 - Tension what!! A case of tension pneumoperitoneum.
Tension what!! A case of tension pneumoperitoneum.

Tension what!! A case of tension pneumoperitoneum

 

Introduction: Patient presenting with gastrointestinal symptoms, are frequently encountered by clinicians in the hospital and indeed the emergency department, where timely diagnosis of pathologies, may have a profound effect on prognosis. The aim of this write-up, is to present a case of delayed diagnosis of a perforated duodenum, leading to patient mortality.

Methods: We collated and obtained the clinical history, laboratory result and radiological investigations.

Results: An 84 year old lady presented to the emergency department with generalised fatigue, myalgia and abdominal discomfort. She was reviewed and assessed by the medical team, who commenced her on antibiotic treatment based on a presumptive diagnosis of bronchopneumonia. Following her admission, her abdominal symptoms worsened which was thought to be due to one of the antibiotics – clarithromycin, that she is being treated with. Clarithromycin was subsequently held. Despite the intervention, she continued to deteriorate clinically and had episodes of haematemesis prompting an urgent OGD. An OGD performed showed a duodenal ulcer.
Despite optimising her treatment, she continues to disimprove clinically. Subsequently, an urgent CT abdomen performed, revealed a perforated duodenum with associated tension pneumoperitoneum.

Pneumoperitoneum is a well-known consequence of gastrointestinal perforation, mechanical ventilation, and abdominal operations. Free intraperitoneal gas is usually a marker of underlying disease and does not in itself pose a hazard to a patient. Tension pneumoperitoneum, on the other hand, is a rare complication in which intraperitoneal gas, under pressure, causes hemodynamic and ventilatory compromise, necessitating urgent intervention (1). In this case, this patient’s symptoms was initially thought and treated as non-specific abdominal discomfort likely related to medication and in retrospect, her symptoms was likely a result of a tension pneumoperitoneum.

Conclusion: This is an unfortunate case, which highlights the importance of a careful and thorough approach when confronted with unclear and sometimes vague signs and symptoms, which patients may present with.

Reference:

Stephanie Y. Chan et al – Tension pneumoperitoneum: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1307551/pdf/westjmed00347-0063.pdf (1)


Adedayo OLAWUNI, Farah MUSTAFA (Drogheda, Ireland), Canberk MESELI, Conor KELLY
08:30 - 17:40 #11740 - The Development Tendency of Emergency Medicine in China.
The Development Tendency of Emergency Medicine in China.

Emergency department (ED) enlargement of 3A hospitals (the top class hospitals in China, possessed more medical resources and better medical teams) became a trend with its development in China during the past 30 years. The mean number of ED visits per year at 2012 (147.4±67.0 thousand) increased than that of 2000 (91.0±59.8 thousand) in 3A hospitals. The gross area, the number of beds also increased, and ED got more attention and more doctors and nurses devoted to the emergency medicine. However, there came some new problems such as ED overcrowding.

With the development of living standard, economic and traffic standard, medical service provided by the low grade hospitals could not meet the need of the patients and it had become more and more convenient for patients to get better medical service in a bigger city. So the need is increased, while the beds is not sufficient. Also effected by the performance inspection systems of hospitals, it had become harder for emergency patients to be admitted to the inpatient wards. To solve this problem and to make sure the security of the badly ill patients, EDs were forced to develop their own inpatient wards and EICUs were established which might be an unique compartment of the Chinese EDs. ED doctors got into a dilemma between ED overcrowding and access block, who also faced more medical disputes and complains during the development. This dilemma leaves the patient waiting for prolonged periods on an ED bed. So in addition to emergency medicine, the Chinese emergency physician needs to have good knowledge in allied specialties, such as critical care and respiratory medicine.

In conclusion, ED expanding was the result of emergency medicine development, but the enlargement of ED should be more rational. We should improve our doctors’ medical skills, optimize the health system, pay more attention to preventive medicine and push hard for health-care reform instead of forcing ED enlargement to satisfy the need for ED.


Zhong WANG (, China)
08:30 - 17:40 #11308 - The Ambulatory Cardiology Unit; an alternative unscheduled care provider.
The Ambulatory Cardiology Unit; an alternative unscheduled care provider.

A recent report from the Kings fund [1] on the status of emergency care in England shows that not only are more patients attending the Emergency Department (ED), but that admissions to inpatient beds from the ED have also increased. Rising admission rates leads to “exit block” from the ED, with fewer inpatient beds available for further admissions. This can lead to overcrowding in the ED, with a knock-on effect on waiting times, contributing to an unsafe environment. [2]

In 2015, the Belfast Trust piloted an Ambulatory Cardiology Unit (ACU). This was based within a Cardiology ward with access to the Cardiac Investigation department, but on a site remote from the ED. The unit consisted of a 4 bedded bay staffed by 1 Cardiologist and 2 Cardiology Nurse Practitioners, and aimed to divert patients with certain cardiology conditions from in-patient admission to rapid assessment within the next few days. We offered access to the ACU as an alternative unscheduled care provider to the ED for patients known to the service.

We have outcome data on patients seen over 1 year. We followed patients up to see if there was an unscheduled care attendance, an emergency admission or mortality at 30 days and 6 months. We found that only 2.9% of patients seen (n=946) presented to hospital with the same condition that they were originally referred with and that 50% of these patients presented to the ACU rather than the ED. Only 1.7% of patients were re-admitted with the same complaint and only 0.2% died from the same complaint (end-stage heart failure).

This service has proved to be safe and effective and has the potential to provide an alternative method for provision of unscheduled care for patients already known to the service. this service provides the ED with an alternative to in-patient admission and also may reduce ED attendances.


Jill BYRNE (belfast, United Kingdom)
08:30 - 17:40 #11393 - The association between scapula fracture and trauma severity in thoracic trauma patients.
The association between scapula fracture and trauma severity in thoracic trauma patients.

Background & Aim: The use of computed tomography (CT) is increasing in trauma patients due to the defensive medical practice and technological facilities. The aim of this study is to detect the correlation between trauma severity and scapula fractures, to determine accompanying injuries and to evaluate the results of conservative approach to scapula fractures.

Patients & Methods: This study has been conducted by analyzing the charts and the medical records of the patients admitted to the emergency department with blunt thoracic trauma during a period of four years. The patients were divided into two groups; group 1: thoracic trauma with scapula fractures and group 2: thoracic trauma without scapula fractures. Age, sex, mechanism of the trauma, type of trauma, physical examination findings, trauma scores and accompanying injuries were evaluated. The diagnostic techniques and co-existence of other system injuries were investigated. Group 2 were evaluated according to their Injury severity score (ISS <9 and ISS ≥ 9). Obtained data were evaluated with 95% CI and p<0.05 was accepted as statistically significant.

Results & discussion: Only 3.7 % (n=77) of 2059 cases admitted to emergency department with thoracic injuries had scapula fractures (group 1) and 96.3 % (n=1982) were without scapula fractures (group 2). No statistically significant differences were detected among age and sex between two groups. Motor vehicle accidents were the most common cause of the injuries. Injury severity score (ISS) was higher in group 1. (Group 1: 18.8±13.2; Group 2: 6.3±8.5; p<0.001). The risk of scapula fracture incidence was detected as 11.3 % in cases with ISS score ≥ 9. In group 1, the number of cases with ISS score <15 was 41 (61.1 %). The most common associating injury in group 1 was rib fracture (44.2 %). The odds ratio of rib fracture in group 1 was 2.4 (%95 CI: 1.5-3.7). The odds ratios of subcutaneous emphysema and non-complicated pneumothorax were 1.9 (%95 CI: 0.9-4.4) and 1.2 (% 95 CI: 0.6-2.5) respectively (Table 1). When the trauma types were analyzed among groups; the percentage of head and facial injuries accompanied to thoracic trauma was 36.4 in group 1. Most of the cases with scapula fracture (90.9 %) were assessed with computed tomography (CT). In 97.4 % of all patients with scapula fracture, conservative treatment was successful in the follow-up.

Conclusion: Scapula fractures are associated with high ISS but also can be seen in low severity thoracic injuries as well. Conservative treatment will be enough in most of cases. Rib fractures are the most common accompanying injury to thoracic traumas although our results were found less than the statistics reported in the literature. But our study has an advantage in detecting the real incidence of blunt thoracic traumas and accompanying injuries due to high diagnostic accuracy of CT.

                                                      


Hatice ALGAN KAYA, Turgut DENIZ, Nesimi GÜNAL, Oğuz EROĞLU, Figen COŞKUN (ISTANBUL, Turkey)
08:30 - 17:40 #10106 - The association between the type of drugs substances used and severity of head injury following road accidents or unexpected events.
The association between the type of drugs substances used and severity of head injury following road accidents or unexpected events.

 

ABSTRACT

Background: psychotropic drugs and psychoactive substances can increase the likelihood of head injuries due to road accidents or unexpected events, there is very less knowledge about the severity of head injury due to consuming these agents. Hence, the present study aimed to assess the relation between the severity of head trauma and the type of drugs used including opiates, cannabis, methamphetamines and benzodiazepines.

Methods: Seventy five patients with moderate to severe head trauma were included into the present cross-sectional study. The severity of injuries was scaled based on the Injury Severity Score (ISS) and Glasgow Coma scale (GCS). Urine sample was screened for drugs and substances using the immunochromatography assay.

Results:  With respect to the type of drug used, 32.0% of cases had no history of drug or substance abuse, whereas 45.3% used one of the substances studies as benzodiazepines in 8%, cannabis or marijuana in 9.3% and opiates in 28%. Also, 22.6% used a combination of these drugs. The severity of injury based on GCS score was independent to the type of drug or substances misused (p = 0.780). Similarly, no difference was found in the mean ISS score as another score for assessing severity of injury and type of drugs used (p = 0.208). Using the multivariable linear regression models, there was no relationship between the type of drug used and brain injury severity in head trauma patients adjusted for gender, age, and injured site.

Conclusion: About two-third of patients with brain trauma due to road accidents or unexpected events had recent history of drugs or substance consuming. The severity of brain injury may be independent to the type drug or substance misused. 


Mohammad Davood SHARIFI (Mashhad, Islamic Republic of Iran), Raheleh FARAMARZI, Elham MASOUMZADEH, Hamideh FEIZ
08:30 - 17:40 #11114 - The Diagnostic Benefit of Mediastinal Width Measurement on Antero-posterior Chest Radiographs for each BMI with Stanford Type A Acute Aortic Dissection.
The Diagnostic Benefit of Mediastinal Width Measurement on Antero-posterior Chest Radiographs for each BMI with Stanford Type A Acute Aortic Dissection.

INTRODUCTION

The 80 mm upper limit for normal mediastinal width (MW) on antero-posterior (AP) chest radiographs was advocated in the 1970s. Despite its relatively poor diagnostic accuracy due to strong effects by patient’s physique, MW has been the most commonly used criterion for acute aortic dissection. We assumed that MW would be reliable if it was paired with body mass index (BMI). The aim of this study was to clarify the diagnostic accuracy of MW for Stanford type A acute aortic dissection (A-AAD) paired with BMI.

METHODS

Between April 2011 and March 2016, the medical charts of patients diagnosed with A-AAD who had an AP chest radiograph and an enhanced CT scan on admission to our hospital and whose body weight and height at the time were recorded were reviewed. Patients were divided into the A-AAD group (n=72) and the control group (n=60) who suffered from mild trauma without any torso trauma. Patients who had a past medical history of aortic disease or thoracic surgery were excluded. Two cardiologists measured the diameters on chest radiographs. The clinical data and the study group were blinded. MW was defined as the maximal distance from the right lateral border to the left lateral border of the superior mediastinum at the level of the aortic knob. MWs of two groups were analyzed retrospectively using the Mann-Whitney U test, on BMI < 25 compared to >= 25.

RESULT

The median MW was 100.7mm (90.5-109.9) in the A-AAD group and 78.7mm (69.1-86.3) in the control group (p<0.001). In BMI < 25, median MW was 99.7mm (90.2-108.1), 71.8mm (64.7-82.4), and in BMI >= 25, it was 105.6mm (95.8-111.9), 82.7mm (78.9-88.2), respectively. According to the receiver operating characteristic curve analysis, MW was a beneficial parameter for the diagnosis of A-AAD, with area under the curve of 0.896. The optimal cutoff values in balancing high sensitivity and specificity were MW=88.2mm (sensitivity and specificity: 83.3%). The area under the curve was 0.924 in BMI < 25, and 0.845 in BMI >= 25. The optimal cutoff values were MW=81.4mm and 95.1mm, respectively.

CONCLUSION

On AP chest radiographs, MW is a useful screening tool for A-AAD, especially showing higher diagnostic accuracy in BMI < 25, but it is relatively favorable as well as in BMI >= 25.


Shota KIKUTA (Yes, Japan), Satoshi ISHIHARA, Keisuke MAEDA, Motoaki ONAKA, Shinichi NAKAYAMA, Nobuaki IGARASHI
08:30 - 17:40 #11258 - The effect of continuous aging population in the operation of the emergency department. (IRD) (Systematic Review).
The effect of continuous aging population in the operation of the emergency department. (IRD) (Systematic Review).

Background: The continuous aging population and declining birth rates bring continuous growth of health needs and health costs. With the new data most health systems of the Members, there will have to undergo significant changes both in the production system - distribution, but also in the funding of the system. This study aimed to investigate the effect of continuing population aging in the efficient and effective operation of the IRD, and the identification and analysis of relevant research relating to the topic.

Methods: This is a systematic review of research articles on the subject matter. The search was conducted in the period covering March to April 2016, the PubMed database, Cochrane library, Willey online library, Google Scholar, with the keywords "Aging population and ICT», «elderly patient and A & E.» «Older people and emergency department »the investigations accession criteria relate to the past 15 years and is written in Greek and English.

Results: identified 97 published articles of which nine met the criteria for inclusion in this systematic review and were mostly cross-sectional quantitative surveys. Through the analysis of the articles, it was found that the use of ICT by the elderly are largely affected both from the operation of the IRD and the wider hospital completeness and availability of beds. Moreover elderly beyond the frequent use of emergency care and ambulance service, require higher health costs and more time in the ED hospitalization. It was also apparent the phenomenon of frequent revisits at the hospital.

Discussion: Through the analysis of the survey, the need for continued systematic monitoring of the emergency department was clearly demonstrated both from the scientific community and by the political leaders who in order to continually reassess the impact of population aging in both ICT and health systems they will have to promptly make the necessary reforms needed to contain health costs, but also simultaneous qualitative and dignified patient care Tues. To age.


Andri EFSTATHIOU (Limassol, Cyprus), Eleni JELASTOPULU, Dafni KAITELIDOU, Mikaella SYMEOU, George CHARALAMPOUS
08:30 - 17:40 #9856 - The effect of fluid therapy on hemodynamic and venous blood gas parameters in patients with septic shock.
The effect of fluid therapy on hemodynamic and venous blood gas parameters in patients with septic shock.

Background: Hemodynamics and venous blood gas (VBG) may be used to guide fluid therapy in
septic shock patients. However, the influence of fluid therapy on hemodynamic and blood gas pa-
rameters is not fully understood. In this study, we aimed to investigate the effect of fluid therapy on
hemodynamic and VBG parameters.
Methods: This cross-sectional study was conducted from January to April 2016. All patients with
diagnosis of severe sepsis were enrolled in the study. Systolic blood pressure (SBP), diastolic blood
pressure (DBP), mean arterial pressure (MAP), central venous pressure (CVP) shock index, VBG
parameters, serum sodium (Na) and chloride (Cl) levels, anion gap, and oxygen saturation (O2sat)
were assessed before fluid resuscitation, after resuscitation, and after fluid challenge test.
Results:
A total of 100 patients were included (mean age were 72.54 ± 12.77 years, 66% male).
Fluid therapy significantly increased DBP (df: 2; F= 4.17; p = 0.017), MAP (df: 2; F= 6.06; p= 0.003),
and CVP (df: 2; F= 27.54; p < 0.001), while the shock index was significantly reduced After fluid
challenge test (df: 2; F= 7.6; p= 0.001). In addition, fluid therapy had no effect on pH (p= 0.90), HCO3
(p= 0.23), base excess (p= 0.13), SCVO2 (p= 0.73), O2sat (p= 0.73), anion gap (p= 0.96), serum Na
level (p= 0.71), and serum Cl level (p= 0.64).
Conclusion: Administration of fluid therapy in septic shock patients had no significant effect on SBP,
heart rate, or blood gas parameters. Future studies on a larger sample of patients should confirm
these findings and correlate them to clinical outcomes

Sahar MIRBAHA (tehran, Islamic Republic of Iran), Alireza BARATLOO, Alaleh ROOHIPOUR
08:30 - 17:40 #11505 - The effect of heat on those exposed to hot and humid environment and their awareness regarding heat related illness.
The effect of heat on those exposed to hot and humid environment and their awareness regarding heat related illness.

Abstract

Introduction

Qatar is a peninsula in the Arabian Gulf with  hot dry climate and low annual rainfall. Increasing heat waves particularly in urban areas where construction is most prevalent highlights a need for heat exposure assessment of those exposed to hot environment. Heat related illness (HRI) affects those individuals who work or excercise in a hot environment where their body is unable to dissipate excess internal heat. The workers at risk of HRI include outdoor workers and those work in hot environment.

Objectives

The aim of the study was to assess the awareness regarding heat related illness among workers exposed to hot and humid environment and the clinical and biochemical effects of heat on these individuals. 

Methods

All individuals coming to emergency department (ED) Alkhor Hospital, Hamad Medical corporation, Qatar during summer 2016 with features of HRI  were included in the study. All participants data were included in a database reporting their age, socio demographic information, nature of work, history of illness, individual preventive measures, hours and duration of work and heat related symptoms experienced during work. They were evaluated in detail including physical examination and blood investigations. Data were analyzed using SPSS 22.

Results

A total of 174 patients were included in the study. All patients were males. Eighty percent were from Bangladesh, India and Nepal as they constitute a major workforce in Qatar. 127 patients (73%) were diagnosed as heat cramps (HC) and 47 (27%) as heat exhaustion (HE). The mean meteorological temperature when patients came to the ED with heat cramps and heat exhaustion was 42.2 0C and 42.47 0C and mean humidity was 49.27 % and 54.28 % respectively. Nearly 86% of the individuals were working outdoor and 79.3% were taking break in between. 93% of the patients drank fluids during their work. Only 37% of them had some basic knowledge regarding HRI. 38% of the patients started developing their symptoms after working for more than 6 hours. The commonest complaint at the time of presentation to ED was muscle cramps (73%) followed by dizziness (68%) sweating (40%) and vomiting (29%). Among our study population ALT ( normal 0-30) was elevated slightly in 48% of patients and AST (normal 0-31) in 28%. Creatinine was higher than normal values ( Normal 53-97 ) in 57.6% of patients and 63% of them had heat muscle cramps. The mean creatinine was 136 in patients with heat cramps and 108 in heat exhaustion. Hyponatremia (Normal 135-145 ) was found in 17.4% of participants.The mean sodium was 144 in heat cramps and 138 in heat exhaustion. There was hypokalemia (normal 3.6-5.1) in 18.6%. Creatine phosphokinase (normal 39-308)  and myoglobin (normal 10-92) were elevated more in heat cramps compared to heat exhaustion. The mean level of CPK was 475 in heat cramps and 241 in heat exhaustion. Myoglobin was elevated in 79.5% of heat cramps and 20.5% of heat exhaustion. There was no mortality.


Firjeeth PARAMBA (Doha, Qatar, Qatar), Hany EBEID, Joost BIERENS, Francesco DELLA CORTE, Osama MOHAMMAD, Vamanjore NAUSHAD, Nishan PURAYIL
08:30 - 17:40 #11379 - The effect of high altitude on central blood pressure and arterial stiffness.
The effect of high altitude on central blood pressure and arterial stiffness.

  1. Central arterial systolic blood pressure (SBP) and arterial stiffness are known to be better

  2. 23  predictors of adverse cardiovascular outcomes than brachial SBP. The effect of progressive

  3. 24  high altitude (HA) on these parameters has not been examined.

  4. 25  Ninety healthy adults were included. Central BP and the augmentation index (AI) were

  5. 26  measured at the level of the brachial artery (Uscom BP+ device) at

  6. 27  4600m and 5140m. The average age of the subjects (70% men) were 32.2±8.7 years.

  7. 28  Compared with central arterial pressures, brachial SBP (+8.1±6.4 mmHg; p<0.0001) and

  8. 29  pulse pressure (+10.9±6.6 mmHg; p<0.0001) were significantly higher and brachial DBP

  9. 30  was lower (-2.8±1.6 mmHg; P<0.0001). Compared <200m, HA led to a significant

  10. 31  increase in brachial and central SBP. Central SBP correlated with AI (r=0.50; 95% CI:

  11. 32  0.41 to 0.58: p<0.0001) and age (r=0.32; 21to 0.41: p<0.001). AI positively correlated with

  12. 33  age (r=0.39; p<0.001) and inversely with subject height (r=-0.22; p<0.0001) weight (r=-

  13. 34  0.19; p=0.006) and heart rate (r=-0.49: p<0.0001). There was no relationship between

  14. 35  acute mountain sickness scores (LLS) and AI or central BP. The independent predictors of

  15. 36  central SBP were male sex (coefficient, t 4.7; P<0.0001), age (t=3.6; p=0.004) and AI

  16. 37  (t=7.5; p<0.0001; overall r2 =0.40; p<0.0001). Subject height (t=2.4; p=0.02), age (7.4;

  17. 38  p<0.0001) and heart rate (t=11.4; P<0.0001) were the only independent predictors of AI

  18. 39  (overall r2=0.43; p<0.0001). Central BP and AI significantly increase at HA. This rise was

  19. 40  influenced by subject-related factors and heart rate but not independently by altitude, LLS

  20. 41  or SpO2. 


Phylip SCOTT (Bristol, UK, )
08:30 - 17:40 #11876 - The effect of sleep apnea on type 2 diabetes and arterial hypertension.
The effect of sleep apnea on type 2 diabetes and arterial hypertension.

Background

The main objectives of this study were to compare the effect of the association between obstructive sleep apnea(OSA) and type 2 diabetes and Blood Pressure.

Methods

An observational, analitical, cross-sectional study was performed on 310 patients with known medical history of type 2 Diabetes. Moreover, the patients were asked to complete the Epworth Sleepiness Scale (which evaluates daytime sleepiness) which were questioned regarding other symptoms related to sleep (snoring, awakenings with choking sensation, respiratory pauses related by the partner).

Results

This study revealed a higher prevalence of OSA in patients with type 2 diabetes. The screening of OSA was performed with a portable device. This study was designed to evaluate the effect of sleep apnea on glycemic control. We found that patients with sleep apnea had greater HbAlc values compared with patients without sleep apnea (9.8% vs. 6.5%, p=0.03).

We demonstrated that each increase of the desaturation index with one episode/hour of sleep was associated with 0.31% increase in HbA1c.

Another objective of this study was to investigate the effect of OSA on blood pressure. Compared with non-OSA subjects, a higher percent of patients with OSA presented high blood pressure values (44.6% of OSA patients and 30.1% of nonOSA patients, p=0.02). These results were confirmed by blood pressure ambulatory monitoring.

Conclusion

Compared with patient without OSA, patients with sleep apnea had significantly higher levels of HbA1c, equivalent with poorer glycemic control. Among parameters evaluated during sleep study, oxygen desaturation index was associated with HbA1c values among patients with type 2 diabetes. No difference was observed regarding blood pressure between patients with and without OSA.


Chirea GABRIELA (Bucharest, Romania), Madalina DUMITRU
08:30 - 17:40 #9904 - The Effects of Physiotherapy in Patients With Chronic Neck Pain. Literature Review.
The Effects of Physiotherapy in Patients With Chronic Neck Pain. Literature Review.

Chronic neck pain is one of most frequent musculoskeletal disorders in adults. It not only disrupts a person's quality of life with very high economic costs. The effects of physiotherapy in this problem are still unclear.The purpose of this study was to review the literature on the effects of physiotherapy in subjects with chronic neck pain.Five bibliographic databases (MEDLINE, EMBASE, CINAHL, Cochrane Library, PEDro) and 90 studies on the effects of physiotherapy in chronic neck pain were review. Adults over 18 years, protocols of electrotherapy, manual therapy, and specific exercises for neck pain were the inclusion criteria. The variable that was taken into account after primary treatment was pain.The study results showed that physiotherapy protocols for neck pain vary from combined monotherapy to authentication protocols. Reduce pain is visible but after physiotherapy protocols combined effects of electrotherapy with specific exercises or manual therapy as satisfactory.The review showed that physiotherapy has satisfactory effects in chronic neck pain but there is not a specific protocol for a particular problem.


Enkeleda SINAJ (Tirana, Albania), Vjollca NDREU, Fatjona KAMBERI, Ermir SINAJ, Yllka THEMELI
08:30 - 17:40 #11579 - The Elder Patient with Suspected Acute Coronary Syndromes in the Emergency Department.
The Elder Patient with Suspected Acute Coronary Syndromes in the Emergency Department.

Background: Elder patients who develop acute coronary syndromes (ACS) have an increased risk of mortality and recurrent myocardial infarction (MI) compared with younger patients.

 The aim of this study is to evaluate the prognostic impact of age in patients with ACS admitted to the emergency department (ED).

Methods: A prospective observational study conducted in ED. Patients were included if they were 18 years or older and were suspected of having ACS, primarily indicated by symptoms considered to be anginal equivalents, ordering of a 12-lead ECG or cardiac biomarkers. Elder was defined as age 75 years or older. We individualized 2 groups: G1 (Elder patients); G2 (Younger patients)

 Results: One hundred seventy three patients were included. Of these, 26 patients (15%) were classified as elders and 147 (85 %) as youngers. Elder patients had a significantly higher proportion of Man (81% VS 66%) and those with hypertension (65% VS 50%), a past history of CAD (12% VS 7%), ST segment depression in ECG (81% VS 74%) but were less likely to be diabetes. Elder patients were significantly more likely to die within 30 days (31% VS 0, 6%; p < 0,001), but there were no differences in the rates of angina recurrence and myocardial infraction respectively between the 2 groups (p= 0, 06; p=0, 41).

Discussion: Ischemic heart disease is a significant problem for the elder population. Among patients who present to the ED with suspected ACS, age should be considered in decision making.


Badra BAHRI (Tunis, Tunisia), Hana HEDHLI, Rym HAMED, Maroua MABROUK, Nader BEN OTHMEN, Wided DEROUICH, Aymen ZOUBLI, Chokri HAMOUDA
08:30 - 17:40 #11909 - The Emergency department of “Hippocration” hospital: performance, lessons and challenges.
The Emergency department of “Hippocration” hospital: performance, lessons and challenges.

 

The question: the current situation of the emergency care in Greece as well as the economic crisis result a different model of emergency care in the country compare to other EU countries, the need to measure, compare and interpret the results under certain criteria. The main criteria could be the overall cost- effectiveness as well as OPIs (operations’ performance indicators) in order to figure out the strengths and weaknesses, within the given operations’ environment, as well as to understand the specific qualities (structure, personnel, procedures of the case).

Methodology:

A wide and concrete basis of statistic data of 2015, 2016 and 2017 that covers all the range of information, has been organized, presented and interpreted. DEA analysis has been used to verify the data and reach quantitative results on productivity, cost and basic OPIs. A first phase of interpretation of the results took place and the main axes of strengths and weaknesses have been addressed.

A second phase of PESTEL and SWOT analysis followed in order to describe the environment and its potential impact on the department, in order to identify the interaction between external environment and the specific qualities of the personnel and the structure, towards goal setting for the near and mid- term future.

Results

A rich set of economic and performance indicators have been extracted by the study, that cover several qualitative and quantitative aspects, all related to the functionality and the potential dynamic of the ER department.

Discussion

The case mix of “Hippocration” ER is related to all the range of incidents and severity of “Heart” problems and also a wide range of surgical and pathological problems. 

Considering the resources devoted (personnel, room, equipment) and the resources absorbed (consumables, drugs) it is clear that the overall volume of services produced is enormous and the productivity can be considered as rather high.  The result of the medical interventions provided (death, successful surgical operation, etc) are assessed also as satisfactory.

Regarding basic OPIs (like waiting times -WT) the results seem interesting since the average, as well as the maximum and minimum time are reasonable; even more the comparison of these WT to other foreign hospitals’ average are proven clearly satisfactory.

Conclusions

Further to the aforementioned interpretation (which will be presented in detail) the targets to be set have been clarified and the actions to be taken can better evident in order to be adopted.  At the same time the barriers that do exist, and should be overcome, are also clearer. This helps to re-organize part of the procedures and the roles.

A big challenge and some people been on board create a good momentum for actions to be taken towards changing interventions.


George CHARALAMPOUS, Anastasia BALASOPOULOU (Athens, Greece), Panos XENOS, Michael CHOUZOURIS
08:30 - 17:40 #11760 - The emergency nursing interest group.
The emergency nursing interest group.

The Emergency Nursing INterest Group

The National Clinical Programme for Emergency Medicine (EMP) was established in 2010. Emergency care in Ireland is currently provided by approximately 1800 providers to 1.3 million patients annually through a network of 28 Emergency Departments (EDs) and 11 Injury Units (IUs. The strategic vsion of the EMP is that all patietns shoudl receive the same standard of high quality emergency care regardless of where in the country they present for treatment.  The Report of the National Clinical Programme for Emergency Medicine (Health Service Executive, 2012) outlines a comprehensive strategic blueprint for emergency care and is the first of it's kind to be developed in Ireland. 

The Emergency Nursing Interest Group was established in 2010 to offer a collective informed view of emergency nursing to the EMP. ENIG offers lead clinical Emergency Nursing staff an opportunity to guide, shape and influence emergency nursing in ireland, currently and inot the future.

The aim of ENIG is to seek and develop constructive critical opinion and expertise on a wide range of key nursing issues in relation to the delivery of quality, safe, timely and cost efficient care to patients who require these services.

The objectives of ENIG are;

- To provide a forum for nurses to be involved in the future strategic development of emergency nursing services development in relation to the EMP.

- To seek ED nurses views with regard to furure resource planning, nursing developments e.g. role of the advanced nurse practitioner in EDs, nurse prescribing of medicineal products and ionising radiation, develop0ing specialised emergency nursing skill sets and responding to change e.g. responsive rostering

- To assist in the preparation and development of discrete pieces of nursing related work required by the EMP

- To support nurses in the implementation of the EMP model of care and programme quality improvement initiatives

- To manages interfaces between the National Clinical Programmes, the Integrated Care Programmes and other nursing fora

to manage interfaces with hospital groups

- Advising and supporting the implementation of healthcare policy relevant to emergency care settings

ENIG is an inclusive rather than exclusive group and with the right emotional committment, skill mix and experience. ENIG will continue to be a key instrument into the furture to ensure that the strategic vision and blueprint of the EMP Report is realised in a relevant way across all Emergency Care settings in Ireland.


Fiona MCDAID (Dublin, Ireland)
08:30 - 17:40 #11000 - The frequency of cardiac incidence in young adults patients complaining by chest pain.
The frequency of cardiac incidence in young adults patients complaining by chest pain.

Introduction:Chest pain is a common symptom among patients contacting the emergency medical services. While it is important to correctly diagnose chest pain patients because of the high-risk nature of some potentially life-threatening disorders it is not feasible to admit every chest pain patient for cardiac work-up due to resource constraints.

The aim of this study is to identify the final diagnosis of patients that are presenting with chest pain in emergency-department and to identify the severity of this diagnosis or if it is justified to underappreciate this symptoms in young patients.

 

Material and Methods:

We used retrospective medical study based on the statistical data from Sibiu Clinical Hospital database. For processing the database and obtaining the final data Microsoft Excel has been used.

We analyzed 127962 cases who have presented in Emergency Department during the period between 01.01.2015-31.12.2016 out of which 7225 have been complaining about chest pain.

Results and Discussions:

From statistical report it is shown that 38.93% were young patients (19-50 years old) and 61.07% patients were over 50 years old. We were interested to examinate how is chest pain distributed in youngs, so we divided them in 3 categories: Category 1(19-30 years) represent 34.55% , category 2 (31-40 years) represent 28.72% , category 3 (41-50 years) represent 36.72%.  In first category was prevalent intercostal nerve syndrome 30.66%, spasmophiliacs 17.49%, neurovegetative dystonia 15.95% and pneumonia 14.61% , while all types of angina represent barely 4.63%. From this group 3.29% patients were hospitalized. In second category was prevalent intercostal nerve syndrome 33.42%, neurovegetative dystonia 15.35%, pneumonia 12.62% and spasmophiliacs 12.25%, while prevalance of angina growed at 9.03% and also high blood pressure growed at 4.83%. From this group 5.57% patients were hospitalized. In third category statistics changed so the prevalent complain was angina 23.81%, intercostal nerve syndrome 19.94% and high blood pressure 17.81%. The hospitalized patients were 13.65%.

Acut coronary syndrome has a bigger prevalence in third category 1.65% than first two ones 0.12%.

Conclusions:

Further investigation about hospitalized patients will be relieved and also what risk factors have each cardiac disorder.

It is easy to see that life threatening disorders have a lower prevalence than non cardiac chest pain disorders, but also is important to indentificate correct chest pain semiotics to be able to deal with life threatening conditions in emergency triage.


Diana Paraschiva LOLOIU, Iris Codruța MD MUREȘAN, Gabriel BOBEȘ, Daniela MD TARAN, Francesca Iulia PĂIUȘ, Bianca Mariana BĂILĂ (Sibiu, Romania), Sorina Madalina PODARIU, Dumitru PAMFILOIU, Anamaria TELEBUȘ
08:30 - 17:40 #10561 - The hidden guilty.
The hidden guilty.

Introduction:

Patient male, 75 years old who preented to Emergency department after having been seen at the Rheumathologist clinic the same day. The rheumatholgist sent the patient to be assessed in our department because the patient was complaining of dyspnoea and central chest disconfort for the last 7 days. The patient had been discharged from internal medicine a month ago due to long term temperature and monoarthritis on the third finger of the left hand (metacarpophalangeal). He was sent home with the diagnosis of suspected septic monoarthritis and urinary tract infection. Medical doctors came to this conclussion after a month of admission and the following complementary tests: Full blood test with ESR of 125 seconds as the only abnormality; Normal abdominal ultrasound; Negative lyme disease test, Normal ECG and Normal Chest X ray and normal urinary test.

Background:

- Hypertension

- Alergic to Non steroidal antiinflamatory drugs.

- Medication: Amlodipine 10 mg per day, Losartan/ Hydrochlorotyazide, Omeprazole, Paracetamol and metamizol.

At the Emergency department:

The patient stayed he was having minimal exertion shortness of breath for the last week, orthopnoea and central chest non specific disconfort. He was still having some temeprature and rigors at night and malais.

On examination:

- PA: 95/45 mmHg

- HR: 125 bpm

-RR: 22 rpm

- Temperature: 37.5

- Cardiac examination: Rhythmic, Diastolic Aortic murmur. Normal pulmonary ausciltation. Jugular ingurgitation.

- Rest of examination was unremarkable.

Complemetary test:

- EKG: Synus Tachycardia.

Clinical decisions and results:

We are in front of a patient with the background described above who presented to us with slight signs of hypoperfusion and pericardial effusion in the context of unknown febrile setting a month ago. With the backgroung in one hand and the clinical presentation today in the other, we transferred the patient to our resusitation room and carried out an Echocardiogrphy which showed a moderate pericardial efussion without signs of tamponade.

A CT- Angiogram of the pulmonary arteries was performed to rule out a Pulmonary embolism and have a look to the main aortic root. The CT angiogram showed: Huge pseudoaneurism in the aortic arc and the ethiology was suspected as Mycotic (infectious aneurism) and confirmed the moderate pericardial effusion.

With that results, the patient was trasnsferred to our intensive car unit and a cardiothoracic ward later on due to the high risk of rupture.

The patient had an Aortic valve replacement  and aortic arc reconstruction at Clinica Ruber in Madrid 24 hours later to our diagnosis. He fully recovered and discharged a week later.

Learning points and discussion:

- The hidden guilty was an uncommon finding: Mycotic aneurism.

- Given the history and the extremely high ESR, how far should we investigate or patients with an unknown focal temperature?

- How useful is the "by the bed" Ultrasound in critical patients?


 


David MATEO SANCHEZ, David MATEO SANCHEZ (Ciudad Real, Spain), Miguel Angel RIENDA, Beatriz BALLESTER, Miguel Angel CARDENETE, Maria Jose PACHECO, Hasania ABDEL-HADI, Rosa Maria MUÑIZ ALONSO
08:30 - 17:40 #10859 - The Hunckback Of Palma.
The Hunckback Of Palma.

A 48-year-old male with a history of rheumatoid arthritis treated with prednisone 10 mg / day, who came to the emergency department due to sudden left subscapular tumor with rapid progression.

He went to external rheumatology consultations two weeks before for back pain after making an effort (he reported having erected a 80kgs stone with a coworker), for which was performed a XRAY that showed ribs fracture of 4º to 8º right posterior costal arches and from 3rd to 8th left posterior costal arches, some with an image suggestive of consolidation process / fracture callus.


In an emergency, stable hemodynamically, afebrile, there is evident deformity in the left dorsal area, indurated, painful, occupying the entire left scapular region and that limits the arches of movements of the left upper limb. Blood analysis without alterations. A thoracic CT is reported as a large hematoma adjacent to the left costal wall in relation to costal fractures of the left costal wall / posterior arches from the 3rd to the 8th rib, which measures approximately 10 x 4 cm from maximum axial diameters, fractures Of the posterior costal arches 4th to 8th.


Evaluated by thoracic surgeon who decides to enter for debridement of left subscapular hematoma in the operating room, procedure performed without complications. Pro evolution post procedure, being discharge at 48 hours.

Conclusion:

Consumption of steroids (0.5% of the general population and 1.7% in women over 55 years) is a clear risk factor for the development of osteoporosis. Prolonged treatment with these drugs increases the risk of fractures with doses as 5mg / day, so it is recommended in this group of patients to prevent osteoporosis (daily physical activity, diet with dairy, solar exposure 10 minutes / day, supplements Calcium and vitamin D).

However, the most common complications of costal fractures are pneumothorax and hemothorax, in our case we have not found a literature on this in costal fractures.


German FERMIN GAMERO, Julio OLSEN TRIULZI (Palma de Mallorca, Islas Baleares, Spain), Edwin PUERTO LARA, Carmen OCEJO, Bernardino COMAS DIAZ, Pere RULL BERTRAN
08:30 - 17:40 #11536 - The impact of a pneumatic tube system on haemolysis in the emergency department.
The impact of a pneumatic tube system on haemolysis in the emergency department.

Background. Haemolysis of serum samples is an important issue in clinical practice. In our emergency department (ED), even 15-25% of samples are affected. Parameters most influenced by haemolysis are potassium (K), lactate dehydrogenase (LDH) and aspartate aminotransferase (AST). The ED needs high-quality laboratory diagnostics as well as quick results to make accurate clinical decisions. We planned a prospective study to evaluate the role of the pneumatic tube system (PTS) for transport of the samples from the ED to the lab in the development of haemolysis.

Methods. In the first part of the study, we compared haemolysis in hand-carried versus PTS transported samples in 50 ED patients. Therefore, two 4,9 mL S-Monovette serum gel tubes were drawn through an 18 or 20-gauge intravenous catheter by the aspiration or vacuum technique and randomised for manual and PTS transport. In the second part of the study, we calculated the difference in haemolysis between samples with and without a 15-minute clotting time prior to PTS transport in another group of 50 patients. We analysed every pair of these samples at the same time on the same analyser within 45 minutes after blood collection.

Results. In the first part of the study, there was 1 mild and 1 moderate haemolytic sample when the serum tubes were hand-carried to the lab. For the PTS transported samples, 4 cases of mild, 6 cases of moderate and 1 case of severe haemolysis occurred. There was a statistically significant difference in haemolysis index (p=0,0012) between the 2 samples in this group. The internationally acceptable difference in result for K, LDH and AST was exceeded in 12 (24%), 24 (48%) and 7 (14%) patients respectively.

In the second part of the study, there were 3 cases of mild and 4 of moderate haemolysis in the immediate PTS transported samples while in the samples that were PTS transported after 15 minutes (of clotting), 3 cases of mild, 2 of moderate and 1 of severe haemolysis occurred. Moreover, in 5 patients the first sample exceeded the internationally acceptable differences for K. The same occurred for 3 patients with the second sample. There was no statistically significant difference in haemolysis index (p=0,2579) between the 2 samples in this group.

Discussion and conclusion. PTS transported blood samples of ED patients are more subject to haemolysis then hand-carried samples. Our study did not demonstrate any benefit of a 15-minute break after sampling before using the PTS. Additional factors that could lead to haemolysis should be studied in blood samples of ED patients to achieve the most reliable test results as soon as possible.  


Yvonne GOOSSENS (Antwerp, Belgium), Laura HEIREMAN, Christa DREEZEN, Boris MAHIEU, Jan STROOBANTS
08:30 - 17:40 #10594 - The impact of mock code drills on the code blue response times.
The impact of mock code drills on the code blue response times.

TITLE PAGE

Title of the article

English: The impact of mock code drills on the code blue response times

Author:

Dr Hany Shahin, MRCEM, FAAEM, EUSEM, EBCEM.

Department(s) and institution(s)

Department of Emergency Medicine, King Abdul Aziz Hospital, Al-Ahsa

 

Corresponding Author:

Name:      Hany Shahin

Address:  Department of Emergency Medicine 213

    King Abdul Aziz Hospital

    Al-Ahsa city, postal code 31982

    Po box 2477, Saudi Arabia

Phone numbers: 0096613-5339999 Ext 36894

Mobile number : 00966502036871

Facsimile numbers:  009663-5910001

E-mail address:  drhani_shahin@yahoo.com

Disclaimers/Disclosure - None

Number of Authors: One

Number of Words: abstract - 236

                                Text - 3408

Number of Tables: Two

Number of Figures: None

Number of References: Twenty five (25)


 

Abstract

 

Objectives:

To evaluate the impact of mock code drills on the time to chest compressions, first dose of epinephrine, and first defibrillation in cardiac arrest.

Methods:

Quasi experimental prospective study was conducted at the King Abdulaziz Hospital. All patients with cardiac arrest were included before and after the implementation of mock code drills. The pre-intervention data were obtained from 1 Jan 2013 to 31 Dec 2013. Intervention (mock code drills) were conducted from 1Jan 2014–28 Feb 2014. The post-intervention data was collected prospectively from 1 Mar 2014 to 28 Feb 2015. The outcome measures were mean time from collapse to chest compression, time from collapse to administration of first dose of epinephrine, and time from collapse to first defibrillation.

Results:

There was a reduction in time from collapse to chest compression from 0.52 minutes [95% CI (-2.1- 1.2)] to 0.37 minutes [95% CI (.15- .58)], time from collapse to administration of first dose of epinephrine from 2.85 minutes [95% CI (1.9-3.8)] to 1.74 minutes [95% CI (1.24-2.30), and time from collapse to first defibrillation remained 1 minute after the intervention.

Student t test revealed statistically significant differences in time to start of chest compressions (p=0.02), and the time to epinephrine administration (p=0.01), while there was no statistically significant difference in administration of defibrillation post-training (p=0.93).

 

Conclusion:

There is a significant improvement in time to first compression and first dose of epinephrine following mock code drills.

 

 


Hany SHAHIN (Lincoln, )
08:30 - 17:40 #11525 - The impact of paramedic provision of pre-hospital intranasal diamorphine on pain scores in paediatric patients with severe pain.
The impact of paramedic provision of pre-hospital intranasal diamorphine on pain scores in paediatric patients with severe pain.

Background; Rapid, safe, and effective analgesia for paediatric patients with severe pain has become standardised in the majority of emergency departments (ED) over the last 2 decades with the introduction of Intranasal Diamorphine (IND).  This route of opiate delivery is as efficacious as the intravenous route and is preferred by children, their parents and health providers.

However, most health systems preclude utilization of IND in the pre-hospital arena by non-physicians, as diamorphine remains a tightly controlled drug, and children with severe pain often suffer from sub-standard analgesia before arrival in the ED.

The Bailiwick of Jersey, whilst a UK dependency, is a separate jurisdiction, and unlike in the UK, registered paramedics may carry and administer IND.

Our study objectives were to introduce and evaluate the efficacy, safety and satisfaction of pre-hospital paramedic delivery of IND in children with severe pain.

Methods; All Jersey paramedics were trained in the use of a standardised patient group direction for the administration of IND (0.1mg/kg) to children (aged 1-16 years) with severe pain due to trauma, who met strict safety inclusion and exclusion criteria, pre-hospital.  Over the 14-month study period children (aged 3-16) underwent validated visual pain score assessment (Wong-Baker FACES) at Time Zero (baseline pre-IND), Time D (>5 minutes post-IND) and Time ED (ED arrival post-IND). All patients underwent non-invasive monitoring for adverse events and patient/parent/paramedic satisfaction scores were measured. 

Results; 14 children met the inclusion criteria over the study period.  The median pain scores were Time Zero = 8 (range 6-10), Time D = 5 (range 2-8), and Time ED = 0 (range 0-6).  The median of differences between Time Zero and Time ED pain score were both statistically (Wilcoxon Signed Rank Test p = 0.001; 95% CI = 4.93-7.36) and clinically significant. There were no serious adverse events and 100% patient/parent/paramedic satisfaction scores.

Discussion; The pre-hospital paramedic provision of IND is safe, and highly effective in reducing severe pain in children and correlates with best practice in the ED. It is well-tolerated by children and their parents, and is both quick and simple to administer by paramedics. Other health jurisdictions should consider lobbying their local law-makers to allow inclusion of this valuable ‘anti-pain weapon’ in their pre-hospital armoury.


Jason HAMON, John MCINERNEY (Jersey, United Kingdom), Vishal PATEL, Sebastian MCNEILLY
08:30 - 17:40 #11500 - The impact of Patient and Public Involvement (PPI) in developing new prehospital quality and performance indicators.
The impact of Patient and Public Involvement (PPI) in developing new prehospital quality and performance indicators.

Background The Pre-hospital Outcomes for Evidence Based Evaluation (PhOEBE) project is working to develop new ways of measuring the quality, performance and impact of ambulance service pre-hospital care. PPI input at all stages of a research project, from initial conception to dissemination, is a prerequisite of good quality research. We aimed to maximise PPI input in this five-year research programme and identify optimal and innovative ways to involve patients and the public in large research studies.

Methods of involvement

PPI were involved in the following ways:

i) Designing and developing the research project; two PPI representatives were co-applicants on the research proposal.

ii) Collaborating with and guiding researchers to focus on meaningful and relevant issues, through the PPI reference group. The group considered PPI issues relevant to the project and advised the research team. PPI members also sat on the project management and steering groups.

iii) Guiding researchers on the best methods of PPI involvement in a multi-stage consensus study.

iv) Designing and co-producing a PPI led consensus event; PPI representatives felt a Delphi study considering technical concepts and language was not an appropriate method of involving PPI. Instead they advocated a face-to-face format which the PPI reference group co-designed and co-facilitated.

v) The PPI reference group were concerned that traditional scholarly outputs would not reach the general public and important messages would be lost. PPI were instrumental in the development and dissemination of an animation which communicates the main messages from the research and is accessible for the general public.

Results

By embedding PPI within our project we were able to prioritise a set of ambulance outcome and performance measures, which reflect not only the preferences of professionals involved in prehospital ambulance care but are important to patient and the public representatives. PPI representatives prioritised issues such as pain management, safety of non-transport decisions, getting the right response first time and new methods of measuring response times and were instrumental in developing ways to communicate these to the general public.

The PPI group were instrumental in the conception and development of a new and innovative method of research dissemination, through the means of a short visual animation. The animation now ensures key messages from this study are accessible to the general public. The PhOEBE animation [https://www.youtube.com/watch?v=Qu7T90_DwV4]

Implications

We identified and utilised a range of methods for involving PPI in large research projects, including new methods of dissemination and the development of a face-to-face PPI consensus event. Patients and the public are well placed to help researchers identify and prioritise quality and performance measures and can maximise dissemination activities, thereby increasing the impact of, and demystifying research for a lay audience. 


Andy IRVING (Sheffield, United Kingdom), Joanne COSTER, Janette TURNER, Andrea BROADWAY-PARKINSON, Maggie MARSH, Dan FALL
08:30 - 17:40 #11864 - The impact of post-disaster public health surveillance on hospital admissions for vector borne and diarrheal disease in Visakhapatnam, India.
The impact of post-disaster public health surveillance on hospital admissions for vector borne and diarrheal disease in Visakhapatnam, India.

Study/Objective:

This study aims to 1) quantify hospital admissions for vector borne and diarrheal diseases and 2) calculate crude morbidity and mortality rates in patients admitted for vector borne and diarrheal diseases at a public tertiary care hospital in Visakhapatnam, India during the 2013, 2014, and 2015 monsoon seasons.

Background:

Cyclone HudHud devastated the coastal city of Visakhapatnam on October 12th, 2014. Anticipating an increase in endemic vector borne and diarrheal diseases following the cyclone, medical teams were deployed throughout Visakhapatnam and the surrounding villages to conduct door-to-door public health surveillance. Community based public health surveillance offers the following benefits:

  • Facilitates early diagnosis and treatment
    • Decreases the number of patients presenting to the hospital emergently
    • Encourages health seeking behavior
    • May decrease morbidity and mortality of cases admitted to the hospital
    • May decrease hospital surge after disaster

Methods:

A retrospective chart review is being conducted at King George Hospital, Visakhapatnam, India. All patients admitted to the hospital and treated for malaria, dengue, or diarrheal diseases from October 19th, 2014 to January 31st, 2015, along with records spanning the same time period 2013-2014 and 2015-2016 will be included in the study. Patient demographic, diagnosis, duration of hospital stay, outcome data will be collected and managed using the web based data collection tool REDCap.

Results:

The study is in progress; data collection and analysis will be completed by August 31st, 2017.

Discussion:

We expect that the utilization of community based surveillance methods in the aftermath of the cyclone may have resulted in lower hospital admission rates for vector-borne and diarrheal diseases as compared to the 2013 and 2015 monsoon seasons, when no such measures were applied.  Public health surveillance methods, including syndromic based diagnosis and treatment are an important mitigation measure not only following disaster, but in the regular monsoon season as well. 


Sravani ALLURI (Boston, USA), Srihari CATTAMANCHI, Amalia VOSKANYAN, Ritu SARIN, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11424 - The impact of raising communities’ disease awareness on the acute stroke patients, an experience of Kaohsiung City.
The impact of raising communities’ disease awareness on the acute stroke patients, an experience of Kaohsiung City.

Objectives:

The previous study has revealed the prenotification by EMS alone just shorten the time of door-to-diagnosis, but not of door-to-drug. Patients' hesitation may contribute the long lapse of CT-to-drug delivery. Therefor, we promoted awareness-raising activities in communities, and joint with the prenotication protocol by EMS, to reduce the onset-to-ED time and door-to-drug time.

Methods:

The survey of communities’ stroke awareness was performed by nursing staffs of local pubic health centers of city government with a 4-problem questionnaire in 2013 and 2014. The questionnaire asked the community people about the stroke warning signs. Meanwhile, we collected the timelines of emergency departments from the citywide stroke registry, required by Department of Health of Kaohsiung City Government. Another observed outcomes were the percentages of ambulance utilization, onset-to-ED <2.5hrs and the door-to-drug <1hr. Yearly parameters were compared with t test and Chi square test.

Results:

There were 2955 and 1183 people respond to the questionnaire in 2013 and 2014, respectively. The mean score of questionnaire was 1.69 in 2013, and improved to 1.97 one year later (p<0.01). The numbers of stroke cases were 2969 in 2013, and 3323 in 2014. The progress of ambulance utilization, from 32.52% to 33.25% (p<0.01), and onset-to-ED < 2.5 hours, from 26.15% to 38.15% (p <0.01) were noted. And the rate of door-to-drug < 1hr has been improved from 37.29% to 61.04% (p=0.02).

Conclusion:

Raising stroke awareness in communities would improve the understanding the stroke warning signs and current thrombolytic therapy. And raising stroke awareness would make patients less ignorance the warning signs, and accept the thrombolytic therapy with less hesitance after disease onset.

Reference:

  1. Hung SC, Kung CT, Lee WH, Cheng HH, Liou CW, et al. (2015) Effects of Pre-Arrival Hospital Notification by Emergency Medicine Service System on Acute Stroke Patients: A New Experience in Kaohsiung City. Emerg Med (Los Angel) 5:284.
  2. Anne Hickey, Deirdre Holly, Hannah McGee, Ronan Conroy and Emer Shelley. Knowledge of stroke risk factors and warning signs in Ireland: development and application of the Stroke Awareness Questionnaire 2012 International Journal of Stroke, 7(4): 298–306
  3. Lin CB, Peterson ED, Smith EE, Saver JL, Liang L, Xian Y, Olson DM, Shah BR, Hernandez AF, Schwamm LH et al: Emergency medical service hospital prenotification is associated with improved evaluation and treatment of acute ischemic stroke. Circulation Cardiovascular quality and outcomes 2012, 5(4):514-522.
  4. McKinney JS, Mylavarapu K, Lane J, Roberts V, Ohman-Strickland P, Merlin MA: Hospital Prenotification of Stroke Patients by Emergency Medical Services Improves Stroke Time Targets. Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association 2011.

Shih-Chiang HUNG (Kaohsiung City, Taiwan), Chia-Te KUNG, Chia-Wei LIOU, Hung-Yi CHUANG
08:30 - 17:40 #10913 - The impact of the clinical pathway in the management of closed chest trauma known as "e;benign"e;.
The impact of the clinical pathway in the management of closed chest trauma known as "e;benign"e;.

Introduction: Thoracic trauma is a frequent reason for consultation with a complex pathophysiology in their analyzes and their evolutions. Concerning the so-called "benign" traumatisms, the question arises of the risk of injury, the assessment of the benefit and the future of patients.

Material and methods: This work is a retrospective study, monocentric over 15 months (11-2009 / 01-2011). His objective was to analyze the modalities of evaluation of so-called minor chest trauma using a clinical path developed in the form of decision algorithms.

Results: We collected 540 files. The sex ratio was 1.75. The average age of 60 +/- 14 years. Falls and AVP are the main causes of survival. 52% of patients had extra-thoracic lesions, 91.5% had chest radiographs and 27% had CT scans. ECG performed in 92% of cases with a troponin dose in 9% of cases. Cardiothoracic ultrasound was performed in 25% of cases. The filling of the clinical paths was adequately filled in 25.23% of the cases

Discussion: The observed attitudes of prize in charge, vary from one doctor to another: only 25% of the clinical paths are fully followed in your entirety. Among the objects, the least filled we find the measurement of the respiratory rate and the evaluation of the pain. However, even if not written in the path, reasoning and decision tree regarding the strategy of complementary examinations as well as patient orientation and sufferings in 94.5% of cases. The paper support with its manual filling may be unused to the completeness of the filling of this path and the arrival of the computer tool will bring, we think, tangible solutions. Moreover, it appeared to us that the cardio-thoracic ultrasound should have more place in the price in charge of the minor traumatism of thoracic.

Conclusion: There is little consensual attitude to the price in charge of benign trauma, in terms of clinical evaluation, indication of complementary examinations, becoming, having such a working tool allows a Simplification of Companies in charge of patients, a clarification of actions and paraclinical explorations in order to optimize human and material resources by reducing the variability of the practices.


Hakim SLIMANI, Philippe KAUFFMANN, Pascal BILBAULT (Strasbourg)
08:30 - 17:40 #11183 - The importance of acute assessment in a case of life-threatening emphysematous pyelonephritis.
The importance of acute assessment in a case of life-threatening emphysematous pyelonephritis.

Emphysematous pyelonephritis is a rare, life threatening acute suppuration of the kidney, characterised by the presence of air in the renal parenchyma, sometimes extending to the surrounding tissue. E. Coli and Klebsiella are the most common causative organisms, but the exact pathogenesis is poorly understood. It carries a high mortality, cited up to 50% and therefore requires prompt diagnosis and management.  A 52-year old woman presented to A+E with a two day history of severe left-sided abdominal pain, rigors, vomiting and increased urinary frequency.  Her past medical history was significant for non-insulin dependent Type 2 diabetes mellitus, a well-established risk factor that is present in 90% of cases. On examination, she had marked left flank tenderness, tachycardia and pyrexia. Bloods showed raised inflammatory markers with a severe AKI.  A CT KUB carried out in A&E showed air bubbles in the parenchyma and calyceal system of the left kidney, which confirmed emphysematous pyelonephritis. As there was no obstruction, the decision was made to manage conservatively.  She was started on intravenous empiric metronidazole and tazocin, aggressive fluid resuscitation and close monitoring of her blood glucose. On day 3, initial blood cultures grew ESBL and tazocin was switched to meropenem and amikacin. A repeat CT scan on day 4 showed complete resolution of the parenchymal gas. Nonetheless, she continued to have recurrent pain and pyrexia. She stayed in hospital for a total of 16 days, with conservative management alone significantly improving her AKI and pyelonephritis. She was discharged with analgesia for residual loin tenderness.   As portrayed in this case, young diabetic women are predisposed to developing emphysematous pyelonephritis. Nephrectomy remains the treatment of choice in most patients, whilst nephrostomy drainage is required in patients with urinary obstruction. Systematic reviews have indicated that antibiotic therapy with nephrostomy carries a reduced mortality risk in comparison to antibiotic therapy with emergency nephrectomy, though there are currently no guidelines available to optimally manage the condition. Prompt CT diagnosis and targeted antibiotic therapy in the initial assessment of this patient were crucial in preventing her from having to undergo an invasive surgical procedure.

 

 


Ree'thee BHATT, Joseph BUTLER (Milton Keynes, United Kingdom)
08:30 - 17:40 #11345 - The importance of early diagnosis and treatment of infectious diseases of the central nervous system.
The importance of early diagnosis and treatment of infectious diseases of the central nervous system.

Varicella zoster virus is responsible for both chickenpox and herpes zoster. The last one occurs on patients over 50 years of age or in states of inmunosuppression. Herpes zoster clinical curse is bening and self-limited most of the time, sometimes it can lead to serious situations that are cause of important morbimortality.

It has been described a clinical presentation of encephalitis associated to herpes zoster exceptionally. Microbiology diagnosis methods had prove the presence of herpes zoster virus on the blood vessels, causing cerebral vasculitis.

We present the case of an 85 year old woman, with no medical history or medication, that comes to the emergency room with feverish feeling and cough with sputum. At the physical examination the vital sings where normal. She was conscious and oriented, with mucosa cutaneous pallor and presence of vesicles grouped in left thorax. Rest of the physical examination was normal.

Blood, urine test and thoracic x-ray were performed, and all were normal. 

She was discharged with the diagnosis of respiratory infection and cutaneous herpes zoster and she was given azithromycin and famciclovir. The next day she presented fever, headache, and mild agitation, so she came back to the emergency room and on the neurological examination she had slight neck rigidity, bradypsychic and nominal dysphasia.

A cranial CT was performed ruling out stroke. Lumbar puncture is performed, which later confirmed meningeolin-optic syndrome.

On suspicion of meningitis we start treatment with acyclovir, cefotaxime and azithromycin. On the second day at the ER the patient presented with dysphasia, right hemianopsia and hemiplegia, and cranial CT was performed with perfusion and angiography.

The MRI angiography showed areas of focal segmental stenosis at the left middle cerebral artery without vascular occlusion. Suspicious on vasculitis due to herpes zoster was made, so we increased the dose of acyclovir and started prednisolone. After 72 hours with the treatment she was without neurological symptoms.

The diagnosis and early treatment of infectious diseases of the CNS is determinant for the prognosis of the patient. The delay of the diagnosis and treatment results in an increase in mortality and irreversible sequel. Therefore, given the minimum suspicion of infection of the CNS, we must discard it, a lumbar puncture should be made, especially if we consider its ease of implementation and the enormous diagnostic yield that provides us.

Vasculitis of the central nervous system is not common, of unknown etiology and potentially serious. Is characterized by inflammation of the vessel wall, which leads either to occlusion or to develop aneurysms that can lead to ischemic and hemorrhagic strokes. Other entities should be considered such as metabolic, demyelinating, and infectious as well as other vasculopathies because they have similar clinical and imaging manifestations.

Bibliography

Wareham DW, Breuer J. Herpes zoster. BMJ 2007; 334:1211.


Noelia SANTOS (Mortera, Spain), Maria Del Pilar CARLOS GONZALEZ, Valentina ACOSTA RAMON, Marta PASTRANA FRANCO, Marta BÁSCONES GARCÍA
08:30 - 17:40 #11801 - The incidence of acute myocardial infarction in patients presenting in Sibiu Emergency Room.
The incidence of acute myocardial infarction in patients presenting in Sibiu Emergency Room.

INTRODUCTION:

Heart disease (coronary artery disease, ischemic heart disease and acute myocardial infarction) is the main cause of morbidity and mortality in Romania, mainly in people over 60 years of age. Lately, the number of young people who die of acute myocardial infarction has increased, without showing any previous signs or suffering.

I proposed to follow the incidence of acute myocardial infarction (IMA) among the patients who presented at the UPU-SMURD of Sibiu County Emergency Clinical Hospital, between 01.01.2014-31.12-2016.

 

MATERIALS AND METHODS

We performed a retrospective observational study based on a number of 190864 observation sheets of the patients presented at UPU-SMURD Sibiu, between 01.01.2014-31.12.2016. Of these, 331 (0.17%) were diagnosed with IMA.

The gender distribution was: 226 men (68.28%) and 105 women (31.72%).

237 (71.60%) patients were from urban and 94 (28.40%) from rural areas.

We considered the following age groups:

31-40 years - 4 (1.21%) male patients, urban environment,

41-50 years - 36 (10.88%) patients, (29 males, 7 females),

51-60 years - 63 (19.03%) patients, (53 males, 10 females),

61-70 years - 87 (26.28%) patients, (66 men, 21 women),

71-80 years - 91 (27.49%) patients, (50 men, 41 women),

81-90 years - 44 (13.30%) patients (20 males, 24 females),

> 90 years - 6 (1.81%) patients, (1 male, 5 female).

The annual distribution of IMA during the study period was as follows:

In 2014 there were 122 patients (36.86% of the total); 46 were women (37.7%) and men 76 (62.30%); 86 (70.50%) came from urban areas and 36 (29.50%) from rural areas.

In the year 2015 there were 112 patients (33.84% of the total), 40 were women (35.71%) and 72 males (64.29%); 82 (73.21%) came from urban areas and 30 (26.79%) from rural areas.

In 2016 there were 97 patients (29.30% of the total), 19 were women (19.59%) and 78 (80.41%) men; 69 (71.13%) came from urban areas and 28 (28.87%) from rural areas.

 

CONCLUSIONS

Patients with IMA represent 0.17% of all patients present during the study at UPU-SMURD Sibiu.

IMA is more common in urban patients (71.60%) and in patients over 60 years (68.88%).

In the 31-70 age group, IMA is more common in male sex (77.89%), in the age group 71-80 years there is a tendency to be equalized between the two sexes, because over 80 years is more frequent to feminine sex.

The study does not find IMA in women under 40 years of age.


Virgiliu Cezar BOLOGA (SIBIU, Romania)
08:30 - 17:40 #11844 - The incidence of allergic cutaneous eruptions or the infectious etiology among adults.
The incidence of allergic cutaneous eruptions or the infectious etiology among adults.

INTRODUCTION

Considering the large number of allergic diseases among the population, we have proposed to track the number of people who have presented for skin rash (allergic or infectious etiology) at UPU-SMURD Sibiu during 2014-2016.

MATERIALS AND METHODS

This retrospective observational study is performed on a total of 190,864 patients, presented at Sibiu UPU-SMURD Sibiu County Emergency Clinical Hospital, between 01.01.2014-31.12.2016. Of these, 606 had rash, being diagnosed as: 392 allergoderm, 123 allergic reaction (post-medication and bee sting), 69 urticaria and 23 infectious disease.

RESULTSOf the 190864 patients presented during the study at UPU-SMURD Sibiu, 606 had rash (0.31%).The annual distribution was the following: 2014 - 323 (53.30%), 2015 - 148 (24.42%) and 2016 - 135 (22.28%) cases.Of these, 436 (71.94%) were women and 170 (28.06%) were men; 356 patients (58.74%) came from urban areas and 250 (41.26%) from rural areas.Depending on the season, the spring was 160 (26.40%), summer - 144 (23.76%), autumn - 131 (21.61%) and winter 171 (28.23%) of patients with rash.During the study, there were 392 patients diagnosed with allergoderma, representing 64.68% of the total.Allergic reaction, diagnosed during the study in 123 patients, represents 20.29% of the total.Urticaria was diagnosed during the study in 69 patients, representing 11.38% of the total.Skin eruptions with infectious etiology were diagnosed in 22 patients (3.65% of total).During the study, patients with rash were divided into age groups as follows: 146 (24.1%) - 18-29 years, 117 (19.30%) - 30-39 years, 104 (17.16% ) - 40-49 years, 80 (13.20%) - 50-59 years, and 159 (26.24%)> 60 years.Of the patients with rash, 28 (4.62%) require hospitalization in the Allergology Section, one patient (0.17%) is hospitalized in the Infectious Diseases Section and the remaining 577 (95.21%) leave with recommendations. CONCLUSIONSDuring the three years of the study, the number of patients who presented themselves at UPU-SMURD Sibiu for rash was low, accounting for 0.31% of the total.The patients considered in the study were diagnosed, approximately 50% in 2014, the remainder, in equal proportions, in the following years.Skin manifestations are more common in women (71.94%) and in urban areas (58.74%).The seasonal incidence of skin rashes is relatively constant, slightly higher in the winter and slightly lower in the autumn.During the study, allergodermia was the most common, and rash of infectious etiology was the most rare.Half of the patients included in the study fall into age groups:> 60 years (26.24%) and 18-29 (24.1%).Only 4.79% of patients with rash require hospitalization.


Virgiliu Cezar BOLOGA, Ramona GANEA (SIBIU, Romania)
08:30 - 17:40 #11807 - The incidence of carbon monoxide intoxications in Sibiu Emergency Room.
The incidence of carbon monoxide intoxications in Sibiu Emergency Room.

INTRODUCTION:

Carbon monoxide poisoning is one of the most common unintended poisoning due to improvisations on heating systems.

MATERIALS AND METHODS

We performed a retrospective observational study based on a number of 190864 observation sheets of the patients presented at UPU-SMURD Sibiu, between 01.01.2014-31.12.2016. Of these, 75 (0.04%) were diagnosed with carbon monoxide intoxication.

Distribution by gender was 32 males (42.67%) and 43 women (57.33%).

57 (76%) of patients came from urban areas and 18 (24%) from rural areas.

The annual distribution during the study was the following: 2014 - 26 (34.67%) cases (12 men, 14 women), 2015-28 (37.33%) cases (9 men, 19 women) and 2016-21 (28%) cases (11 males, 10 women).

The CO intoxication occurred as follows: during the spring 16 (21.33%), in the summer months, 4 (5.34%), in the autumn 16 (21.33%), and in the winter months 39 (52%) In the winter months.

Distribution by age group was as follows:

18-30 years - 21 cases (8 males, 13 females),

31-40 years - 18 cases (7 males, 11 women),

41-50 years - 13 cases (6 men, 7 women),

51-60 years - 9 cases (5 males, 4 females),

> 60 years - 14 cases (6 males, 8 women).

It is worth mentioning that there are situations in which patients come, two or three, of the same family.

Of the patients with CO intoxication, only 15 (20%) required hospitalization in the Medical Section, the rest left with recommendation.

 

CONCLUSIONS

The number of patients with CO intoxication represents 0.04% of the number of patients who presented themselves during the study at UPU-SMURD Sibiu.

Annual distribution of cases is relatively constant and all groups are interested in age.

CO intoxications are more common in urban areas (76%).

Gender distribution shows a slightly higher frequency of CO intoxications in women (57.33%).

Most CO intoxications occur in the winter months (52%), and the lowest in the summer months (5.34%), the rest is evenly distributed in the spring and autumn months.

Only 20% of patients with CO intoxication required hospitalization.

 

 


Virgiliu Cezar BOLOGA (SIBIU, Romania)
08:30 - 17:40 #11863 - The incidence of pancreatitis in the emergency department.
The incidence of pancreatitis in the emergency department.

BACKGROUND

Pancreatitis is a severe disease which requires immediate diagnosis and treatment. Without emergency intervention, it can lead to death.

MATERIALS AND METHODS

This study was performed through a retrospective observational method, on a number of 190864 patients admitted to the Emergency Department of Sibiu County Clinical Emergency Hospital between 01.01.2014-31.12.2016, out of which 297 patients were diagnosed with pancreatitis.

RESULTS

Out of 190864 patients presented at the Emergency Department of SMURD Sibiu during this period of time, 297 were diagnosed with pancreatitis(0.16%).

The acute forms (252) represents 84.85% with the following annual distribution: 89cases(35.32%) in 2014, 96 cases(38.10%) in 2015 and 67 cases(26.59%) in 2016; 87 were women(34.52%) and 165 were men(65.48%); 151 patients(59.62%) came from the urban setting and 101 patients(40.08%) came from the rural setting.

The distribution of age groups during the study was: 20-29 years-7 patients(2.78%), 30-39 years-17 patients(6.75%), 40-49 years-54 patients(21.43%), 50-59 years-39 patients(15.48%), over 60 years-135 patients(53.57%).

Out of those with acute pancreatitis, 102(40.48%) received treatment in the Gastroenterology Department, 128(50.79%) in the Surgery Department, 1(0.40%) in the Nephrology Department and 1(0.40%) in the Nutrition and Dietetics Department; 7 patients(2.78%) were discharged with a referral letter and 13(5.16%) refused hospitalization.

Chronic forms of pancreatitis(45cases) represent 15.15% distributed per years as: 16 cases(35.56%) in 2014, 15 cases(33.33%) in 2015 and 14 cases(31.11%) in 2016.

Out of those with chronic pancreatitis 8(17.78%) were women and 37(82.22%) were men; 31 patients(68.89%) came from the urban setting and 14(31.11%) came from the rural setting.

The distribution of age groups in the period of the study was: 20-29 years-2 patients(4.44%), 30-39 years-5 patients(11.11%), 40-49 years-10 patients(22.22%), 50-59 years-15 patients(33.33%), over 60 years: 13 patients(28.89%).

Patients with chronic pancreatitis received treatment in: Gastroenterology Department 19(42.22%), Surgery Department 4(8.89%), Cardiology Department 1(2.22%); 14 patients(31.11%) were discharged with a referral letter and 7(15.56%) refused hospitalization.

CONCLUSIONS

The number of patients diagnosed with acute pancreatitis was constant between the years 2014 and 2015 but it went down in 2016.

The number of patients with chronic pancreatitis was stable during the study.

Pancreatitis was more frequent in men and in urban setting.

Most patients with acute pancreatitis were admitted in the Surgery Department followed by the Gastroenterology Department. The patients with chronic pancreatitis were treated mainly in the Gastroenterology Department.


Virgiliu Cezar BOLOGA, Andreea-Liliana BOCAI (Sibiu, Romania), Dr Iulia Francesca PAIUS, Lucian CALUTIU
08:30 - 17:40 #10938 - The influence of a pesticide poisoning pattern by prohibition of paraquat sales.
The influence of a pesticide poisoning pattern by prohibition of paraquat sales.

Introduction: Korea represents high suicide rate by poisoning. Especially, since a lot of died by high concentrated paraquat which has extremely high fatality rate, paraquat sales were prohibited in 2012. We investigated to find out how the prohibition of sales affected occurrence of pesticide poisoned patients and what kinds of influences did it have for severity and death rate. Subjects and Method: By targeting patients who visited emergency room by pesticide poisoning from 2010 to 2014, we researched insecticides poisoned patients and herbicidal poisoned patients grouped into 10 categories. Before and after 2012, we compared A term(2010, 2011) and B term(2013, 2014)'s pesticide occurrence, especially distribution of herbicide occurrence and compared hospitalization rate, hospitalization period, length of stay in ICU(Intensive Care Unit), severity, and death rate. Result: The number of insecticide patients was 218(37.0%) and the number of herbicide patients was 371(63.0%) who visited emergency room in five years and the rate was similar every year. In case of paraquat, there was 29.8% decrease by 104 people for A term and 31 people for B term and increase of double for glyphosate, glufosinate, and other herbicides. The death rate was decresed but hospitalization was increased. There weren't any difference of rate in ICU admission, intubation and ventilator therapy. Conclusion: By prohibition of using paraquat, the death rate by pesticide poisoning was decreased. However, patients who poisoned by other herbicides were increased, so hospitalization rate increased and there weren't any difference at patient's severity rates.


Soohyung CHO, Soohyung CHO (Gwangju, Republic of Korea), Yongjin PARK
08:30 - 17:40 #10737 - The influence of emergency physicians on medical negligence claims in the Emergency Department, a retrospective cohort study.
The influence of emergency physicians on medical negligence claims in the Emergency Department, a retrospective cohort study.

ABSTRACT

Introduction. Several studies state the efficacy of specialty trained emergency physicians. In this study we aim to investigate the impact of the introduction of emergency physicians on quality of care as measured by medical negligence claims in Dutch Emergency Departments (ED).

 

Methods. We performed a multi-centre retrospective cohort study on negligence claims in five Dutch EDs. A Poisson regression model was used to compare medical negligence claims before and after the introduction of emergency physicians.

 

Results. A significant reduction of 31,4% (p <0,01) in negligence claims was seen after emergency physicians were introduced in the ED. This reduction was even more pronounced when emergency physicians were present 24/7 (37.8%, p 0,04).

 

Conclusion. Despite an increase in overall ED patient throughput and despite a growing claim culture in The Netherlands, the number of medical negligence claims filed after an ED visit was significantly reduced when emergency physicians were introduced in the ED. 


Luuk WANSINK (Amsterdam, The Netherlands), Maybritt I. KUYPERS, Tom BOEIJE, Crispijn L. VAN DEN BRAND, Manon M.j. DE WAAL, Ewoud TER AVEST, Joris HOLKENBORG
08:30 - 17:40 #11492 - The influence of the teacher in the acquisition of knowledge and skills related to cardiopulmonary resuscitation in schoolchildren. Anxos Project.
The influence of the teacher in the acquisition of knowledge and skills related to cardiopulmonary resuscitation in schoolchildren. Anxos Project.

Objective. To describe the influence of the teacher in the acquisition of knowledge and skills in schoolchildren.


Methods: Participants 777 students, including Year 1 at Secondary School and Years 3 and 5 at Primary School and their corresponding 12 Physical Education teachers from four different Galician schools.

Firstly, the teachers received their appropriate training course, followed by the subsequent two- hour course for the students, dealing with the sequence of basic life support and the Heimlich manoeuvre with feedback. Subsequently, students’ skills and general knowledge were assessed with the software Wireless Skillreporter® without feedback.

Results: Several differences were observed among the teachers of the same year when protecting, appreciating consciousness, asking for help, opening airway, and calling the EMS (p<0,005). In addition, the parameters for the rate of compression (p<0,05) provided by the Wireless Skillreporter® software among students of different teachers who taught in the same year were different.

Conclusions: It is very important to stress during training on the relevant aspect of the sequence of basic life support. Furthermore, a good explanation of the non-modifiable parameter by gender, weight or size, becomes basic to achieve good results. 


Maria PICHEL LOPEZ, Luis SANCHEZ SANTOS (Santiago de Compostela (A Coruña), Spain), Roberto BARCALA-FURELOS, Santiago MARTÍNEZ-ISASI, David VAZQUEZ-SANTASMARIÑAS, Antonio RODRIGUEZ NUÑEZ, Felipe FERNÁNDEZ-MÉNDEZ, Cristina VARELA CASAL, Noelia VIGO-RIVAS, Antonio IGLESIAS VAZQUEZ
08:30 - 17:40 #10111 - The Interaction Effect between Transport Time Interval and Scene Time Interval on Good Neurological Recovery after Out-of-hospital Cardiac Arrest Patients without Prehospital Return of Spontaneous Circulation.
The Interaction Effect between Transport Time Interval and Scene Time Interval on Good Neurological Recovery after Out-of-hospital Cardiac Arrest Patients without Prehospital Return of Spontaneous Circulation.

Aim: The aim of this study was to examine whether the effect of longer transport time interval (TTI) on neurologic outcomes of OHCA patients without prehospital ROSC differed by scene time interval (STI).

Methods: We used a Korean national OHCA database from 2012 to 2015. We included adult OHCA patients with presumed cardiac etiology. We excluded patients whose arrest was witnessed by EMS or if prehospital ROSC was achieved. The primary exposure was TTI, which was categorized into short (1-5 min), intermediate (6-10 min), and long (11 min or longer). Scene time interval (STI) was categorized into short (1-5 min), and long (6 min). The primary outcome was good neurological recovery at discharge (cerebral performance category 1 or 2). Multivariable logistic regression analysis was performed to evaluate the effect of TTI on outcome. The final model with an interaction term was evaluated to compare the effects across STI.

Results: Among 108,253 patients, 58,904 patients were analyzed. 23,081 (39%) patients were belonging to short TTI group, 21,010 (36%) patients were belonging to intermediate TTI group, and 14,813 (25%) patients were belonging to long TTI group. Good neurological recovery was highest in the short TTI group (3.4%) compared to intermediate TTI group (2.4%) or the long TTI group (1.5%). When referencing short TTI group, adjusted OR of TTI for good neurological recovery was 0.59 (0.46-0.74) for intermediate TTI, and 0.53 (0.38-.073) for long TTI. In the interaction model, adjusted OR of TTI for good neurological recovery was different between short STI group (aOR (95% CI): 0.38 (0.25-0.56) in intermediate TTI group, 0.33 (0.19-0.57) in long TTI group) and long STI group (aOR (95% CI) 0.76 (0.56-2.02) in intermediate TTI group and 0.70 (0.60-0.81) in long STI group).

Conclusion: We found that longer transport time interval adversely affect to good neurologic recovery of OHCA patients without prehospital ROSC, and that negative effect was intensified if patients received insufficient resuscitation at scene.


Park JEONG HO (Seoul, Republic of Korea), Kim YU JIN, Kim SOLA, Ro YOUNG SUN, Shin SANG DO, Kong SO YEON
08:30 - 17:40 #11744 - The interest and previous experience in humanitarian work of emergency medicine residents in the Philippines.
The interest and previous experience in humanitarian work of emergency medicine residents in the Philippines.

INTRODUCTION

The Philippines is on the top 5 list of the countries that are most frequently affected by disasters. In November 2013, the typhoon Haiyan yielded a total of 16 million people affected and 6300 deaths. Future generations of Filipino emergency medicine physicians should be particularly acquainted with humanitarian aid work. This study aimed to explore the interest, previous experience and future intentions of Filipino emergency medicine (EM) residents.

METHODS

From November 2015 to April 2016 an electronic survey was sent to all the EM residents enrolled in the 12 EM training programs in the Philippines. The questionnaire explored participants’ previous humanitarian experience, existing humanitarian work opportunities in their respective training programs, participants' interest to engage in humanitarian work after completion of their training and related motivations and concerns. Frequencies were used to describe participants’ characteristics. Confidentiality of information was ensured and no financial incentive for participants was offered. The Institutional Review Board considered the study to be exempt from approval.

RESULTS

Ten of the 12 EM training programs in the Philippines (83%) participated in the study; all the 131 EM residents enrolled in those programs were contacted and 63 completed the survey (RR 48.09%). A total of 48% were males and the median age was 31. A total of 42.9% had experience working with humanitarian organizations (mostly with the Philippine National Red Cross and local NGOs). The majority of respondents (71.4%) had the opportunity to participate in humanitarian work within their training programs. For half of the respondents (55.6%) there was no prior training available. A total of 82.6% either agreed or strongly agreed to the statement "I would like my current training program to provide more opportunities to participate in humanitarian work”. Overall, 53 respondents (84.2%) considered participating in an humanitarian aid mission after their training and 38 (60%) considered a career in the humanitarian field. The top 3 motivations of those considering humanitarian work were: desire to help others and save lives, personal/professional development as an emergency physician and desire for a new experience. Safety and security were the most frequently cited concerns. Living conditions and negative impact on their personal income were the 2nd and 3rd most frequently chosen issues.

CONCLUSIONS

Compared with doctors in training in other countries, Filipino EM residents engaged much more in humanitarian work, mostly with local organizations. Humanitarian work opportunities were well-represented across EM training programs even if few of them offered prior training. Residents’ interest to work in the humanitarian field after their training was high; altruism and personal growth were the most stated motivations while safety and security represented the main concerns.


Natasha REYES, Luca RAGAZZONI (Novara, Italy), Alba RIPOLL GALLARDO, Francesco DELLA CORTE
08:30 - 17:40 #11749 - The introduction of injury units in Ireland.
The introduction of injury units in Ireland.

The report of the National Clinical Programme for Emergency Medicine  published in 2012 was the first strategy to improve safety, quality, access and value in Emergency Medicine in Ireland. In 2009 Ireland had 41 24 hour Emergency deaprtments, a relatively large number for a population of 4.5million. This relatively large number of EDs led to numerous challenges in governance and the maintenance of an appropriately skilled workforce. The Report proposed 3 type of unitsehich would form an Emergency Care Network; Type A - 24 hour 7 day Emergency Department, Type B - 12 hour 7 day Local Emergency Department, Type C - 12 hour 7 day Injury Unit. This abstract focuses on the introduction of Injury Units (IUs).

The IUs aim to provide unscheduled care for patients with non-life threatening or non-limb threatening injuries, as conveniently as possible, while ensuring patient safety and equitable standards of care within the Emergency Care Network. These units are open to new patients from 08:00-20:00 hours. IUs are generally in Model 2 hospitals, although there are some standalone units. Model 2 hospitals deliver scheduled care, except for the IU which does not require referral by a primary care physician to be seen.

The IUs operate within a defines criteria for patietns over 5 years of age. Protocols are in place to manange patients who present with complaints outside the defined criteria to re-direct them to the most appropriate facility.

The introduction of the IUs has been positively received by those who have used them as the turn-around time is much shorter than in EDs, generally leaa than 2 hours. Currently the IUs are staffed by a mix of registered Nurses, Advanced Nurse Practitioners and doctors, though there are plans to have IU predominatly Advanced Nurse Practitioners led. It is anticipated that further IUs will be developed in the coming years as the delivery of healthcare is restructured.


Fiona MCDAID, Fiona MCDAID (Dublin, Ireland)
08:30 - 17:40 #10914 - The non-operative treatment of a fracture of the humeral glenum associated with an anterior dislocation of the shoulder. About a case.
The non-operative treatment of a fracture of the humeral glenum associated with an anterior dislocation of the shoulder. About a case.


A 45-year-old man with no notable medical history is admitted to the ER for the management of right shoulder trauma following a mechanical fall on the stairs. The patient had a total and painful functional impotence of the shoulder and with clinical examination a characteristic aspect of antero-inferior glenohumeral dislocation without signs of root pain. The frontal radiograph showed a fracture of the glenoid cavity of the Goss-Ideberg scapula type I.b with a lower luxation (Figure 1.A). The dislocation was easily reduced by external manipulation according to the Kocher technique, under analgesia with satisfactory radiographic control (Fig.1.B). CT with reconstruction (Fig.1.C / D) revealed a fracture especially at the expense of the antero-inferior part of the glenoid cavity. The treatment was orthopedic with immobilization elbow to the body for 15 days associated with early proprioceptive rehabilitation. The trend remains favorable at 12 months. The anterior dislocations of the shoulder associated with the fractures of the glenoid cavity have an incidence reported between 5% and 50% according to the series (1). Fractures of the flap of the Goss-Ideberg type I scapula which occur during a lateral impact of the arm in adduction are to be differentiated from the glenoid displacements which occur during the previous dislocations with an abduction and rotation mechanism lateral. Optimal treatment is controversial, but surgical repair is generally preferable in order to avoid recurrent instability. However, it is unclear whether a fracture of the glenoid rim predisposes instability to justify surgical repair from the outset. The data in the literature are based on the size and displacement of the glenoid fragment. Maquieira et al (2) reported encouraging results in a series of 26 cases of anterior dislocations of the shoulder associated with a glenoid margin fracture (a fragment> 5 mm and a displacement> 2 mm) all treated orthopedically Of satisfactory post-reduction radiographs with a well-centered scapulo-humeral joint. Our patient did not show any dislocation and regained a preserved joint amplitude.

1- Sugaya H, Moriishi J, Dohi M, Kon Y, Tsuchiya A. glénoïdien jante morphologie récurrente instabilité scapulo - humérale antérieure. J Bone Joint Surg [Am] 2003; 85-A: 878 -84

2- Maquieira G. J, Espinosa. N,Gerber.C, Eid. K. Non-operative treatment of large anterior glenoid rim fractures after traumatic anterior dislocation of the shoulder. J Bone Joint Surg [Br] 2007;89-B:1347-51


Hakim SLIMANI, Abdellah BEN AOUMAR (Belfort), Luc SENGLER
08:30 - 17:40 #9855 - The Prevalence of Personality Disorders in Nurses; Role of the Workplace Environment.
The Prevalence of Personality Disorders in Nurses; Role of the Workplace Environment.

Introduction: Personality disorder is a multi-factorial condition in which workplace stress plays
a significant role. Scarcity of information regarding the role of workplace stress in onset of
personality disorder among nurses led to designing the present study, aiming to evaluate the
prevalence of personality disorders in nurses working in different hospital departments and
assess factors affecting its onset.
Methods: The present study is a cross-sectional one, in which the personality disorders of nurses
working in various hospital departments were evaluated based on Minnesota Multiphasic
Personality Inventory-2 (MMPI-2) test. When the questionnaires were filled, data were entered
to MMPI-2 test’s special software and the final result was interpreted based on the opinion of a
clinical psychologist. Finally, multivariate logistic regression model was used for assessment of
independent effect of the mentioned factors on prevalence of personality disorders in nurses.
Results:In the present study, data from 206 nurses, in 2 groups ofemergency and other units
(mean age 32.5 ± 6.9 years),were gathered. Overall,54.3%(38)of the non-emergency nurses
versus 45.7% (32) of emergency nursesshowed symptoms of personality disorders. Multivariate
logistic regression analysis showed that history of a serious accident or trauma increased the
odds of detecting personality disorders up to 3.8 times (OR = 3.84; 95%CI: 1.33 - 11.06; p =
0.01) and an unpleasant incident in the past year increased it up to 2.2 times(OR = 2.23; 95%CI:
1.18 – 4.22; p = 0.01)in both groups.
Conclusion:The present study showed that there is no significant difference between emergency
departmentand other units of hospitalregarding prevalence of personality disordersin
nurses.Overall,somatization, hysteria, and pollyannish were the most common personality
disorders among the studied nurses.

Sahar MIRBAHA (tehran, Islamic Republic of Iran), Alireza BARATLOO, Alaleh ROOHIPOUR
08:30 - 17:40 #11325 - The prognostic value of high-sensitivity cardiac troponin in early diagnosis and risk stratification of acute coronary syndrome.
The prognostic value of high-sensitivity cardiac troponin in early diagnosis and risk stratification of acute coronary syndrome.

Background

Acute coronary syndrome (ACS) remains one of the major causes of mortality and morbidity worldwide, despite large knowledge gathered also in the past years about diagnosis and management. Emergency department's care of patients with possible ACS is complex and challenging. Current ESC and ACC/AHA guidelines recommend risk stratification using various published risk scores and clinical assessment. It allows for an appropriate therapeutic strategy and an effective allocation of various resources.

Materials and Methods

Search of PubMed, Google scholar, J-STAGE for relevant publications and other official documents on the subject. Articles since year 2009 which met basic thematic criteria were included for analysis.

Results

The review of studies and standards showed several key points. A major role in early diagnosis of ACS and further prognosis and risk stratification have cardiac biomarkers. Studies have shown cardiac troponin (cTnI and cTnT) to be the most sensitive and specific biomarkers for miocardial injury. While the high sensitivity and specificity of troponin may have improved diagnostic accuracy for ACS in the emergency department and hospital,there may be a delay of several hours in elevation of the biomarkers depending on the time between symptom onset and presentations. This causes a delay in diagnosis and further outcome.

Discussion

With advances in technology, a new chapter in troponin assays is opening. Based on their analytic capabilities, the high-sensitivity assays allow for earlier and faster recognition of ACS patients and gives clinicians a path to more quickly diagnose. As previously mentioned, they are extremely sensitive, detecting concentrations of the same proteins that conventional assays are aimed at detecting, just in much lower concentrations.

However, high-sensitivity TnT values were associated with high physical activity, age, presence of anemia, tachyarrythmias, pulmonary embolism, sepsis and less with ECG left ventricle hypertrophy signs, showing decreased specificity for myocardial injury. High-sensitivity Tn assays specificity will be determined when its values will be established. That way high-sensitivity biomarkers create new challenges in research and increasing responsibility to assign each test in clinical context.

Also, elevated values and changes in values over time of troponin correlate with risk of adverse cardiac events in the next weeks after ACS.

Conclusion

Testing high sensitivity cardiac biomarkers along with clinical tools for risk stratification creates a better separation of risk profile and consequently improves risk prediction of cardiac events.


Victoria MELNICOV (Chisinau, Moldova), Gheorghe CIOBANU
08:30 - 17:40 #11436 - THE PROTECTIVE EFFECT OF CARNOSINE ON HEPATIC ISCHEMIA-REPERFUSION DAMAGE.
THE PROTECTIVE EFFECT OF CARNOSINE ON HEPATIC ISCHEMIA-REPERFUSION DAMAGE.

 

Aim: This study was performed to investigate the antioxidant effects of carnosine in rats exposed to hepatic ischemia-reperfusion (I/R) injury by biochemical and histopathological evaluation.

Material and Methods: Twenty-four Sprague-Dawley male rats weighed 200-250 g were used to investigate the antioxidant effects of carnosine on the liver. Rats were randomly divided into 3 groups, each consisting eight rats; sham (control) group (G1), hepatic ischemia-reperfusion group (G2), and hepatic ischemia-reperfusion group treated with 100 mg/kg carnosine (G3). Rats in the control group underwent only laparotomy and catheterization. Other groups received 2 h reperfusion following 1 h hepatic ischemia by hepatic artery clamping after laparotomy. Rats in the treatment group received an intraperitoneal (IP) injection of 100 mg/kg carnosine 60 min before the hepatic artery clamping. Rats were monitored for blood pressure, heart rate and fluid intake. At the end of the reperfusion, blood samples for aspartate transaminase (AST), alanine transaminase (ALT) and liver tissue samples for tissue malondialdehyde (MDA), glutathione catalase (GSH) and catalase (CAT) as well as for histopathologic examination were taken.

Results: Significantly decreased serum AST, ALT, and MDA levels and significantly increased GSH and CAT levels were found in the treatment group compared to group exposed to only I/R injury. In regards to histopathological changes in the liver, less injury was seen in rates received carnosine.

Conclusion: Considering the significant biochemical and histological effects of carnosine, we concluded that carnosine may be effective in preventing the oxidative damage on liver tissue due to ischemia-reperfusion injury.     

  


Sabiha SAHIN (Eskisehir, Turkey), Ufuk UYLAS, Varol SAHINTURK, Ozkan ALATAS
08:30 - 17:40 #10998 - The quick Sepsis Organ Failure Assessment criteria (qSOFA) at triage in patients presenting to the emergency department (ED): Relation to outcome.
The quick Sepsis Organ Failure Assessment criteria (qSOFA) at triage in patients presenting to the emergency department (ED): Relation to outcome.

The quick Sepsis Organ Failure Assessment criteria (qSOFA) at triage in patients presenting to the emergency department (ED): Relation to outcome.

Myrto Bolanaki, Anna Slagman, Martin Möckel

Department of Emergency and Acute Medicine (CVK, CCM),

Charité -Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin

 

Introduction

The Third International Consensus Definitions for Sepsis introduced the qSOFA score to be used in the ER to identify patients with suspected infection who are at higher risk of poor outcome.  Data on the frequency of an elevated qSOFA-score in the ED and the association with the development of sepsis are limited.

 

Objective

To estimate the frequency of patients presenting to the ED with at least 1 qSOFA point according to the triage documentation at admission and the association of an elevated qSOFA-score and the development of sepsis within the first 96 hours.

 

Methods

The screening population consisted on all adult non- trauma patients who presented in the ED of two large tertiary hospitals in Berlin between 11th Nov 2016 and 17th Nov 2016. The qSOFA criteria were assessed in the initial triage documentation: SBP≤100 mmHg, respiratory rate ≥22 breaths per min, or altered mentation (Glasgow coma scale<15). Exclusion criteria were: 1. acute coronary syndrome; 2. pregnant women; 3.suspected stroke. All electronically documented routine data were retrieved from the hospital information system (HIS).  Sepsis was defined according to the Third International Consensus Definitions for Sepsis.

 

Results

Of 1,112 screened patients, 7.6% (n=85) had an elevated qSOFA score and no exclusion criterion. Of these patients, 91.8% (n= 78) presented with 1 qSOFA point, 7.1%(n=6) with 2 qSOFA points , and 1,2% (n=1) with 3 qSOFA points (see figure). Sepsis was coded in 8.2% (n=7 out of 85), while the outcome of 8.2% (n=7) remained unknown since they were transferred to another clinic.

 

Conclusions

In our study, we were able to demonstrate that patients with suspected organ dysfunction on the basis of qSOFA criteria present frequently to the ED (7.6 %).   8.2% of these developed a sepsis within 96 hours after ED presentation. Most of the patients had only one qSOFA point.


Myrto BOLANAKI (Berlin, Germany)
08:30 - 17:40 #11897 - The relation between Type 2 Diabetes and Obstructive Sleep Apnea in Obese patients.
The relation between Type 2 Diabetes and Obstructive Sleep Apnea in Obese patients.

Background

Nowadays, the prevalence of diabetes and obesity has reached epidemic proportions. Although it is a fact that diet and reduced physical activity along with stress and genetic predisposition are the main causes of Diabetes, recently, obstructive sleep apnea(OSA) is seen as a risk factor for obesity, insulin resistance, type 2 diabetes mellitus and metabolic syndrome. The observed association have important clinical, epidemiological and public health implications.

Methods

A number of 310 patients with type 2 diabetes and a BMI > 27kg/m were included in a descriptive, cross-sectional study. First, every patient completed Epworth Sleepiness Scale, for the screening of OSA. In those patients with a score over 10 points, a polysomnography was performed, which is considered the gold standard for the diagnosis of sleep disorders.

Results

Based on symptoms and sleep study, 42.3% of the study participants (179 patients) were diagnosed with sleep apnea and in all cases sleep apnea was obstructive. Regarding the severity, only 23.6% had “severe” sleep apnea (AHI >30 events/hour of sleep). Also, OSA was more common in male patients compared with females (37.2% vs. 26.8%, p= 0.04). Considering age groups, 48.7% of cases were present in younger patients (below 50 years of age), a surprising result if we think that in general population, prevalence of OSA increases with age.

Conclusions

The main conclusion of this study is the high prevalence of undiagnosed symptomatic sleep apnea in obese patients with type 2 diabetes: 22.3%, higher in males than in females. In 8 diagnosed cases, it was a moderate or severe form of OSA, requiring treatment in order to increase quality of life and prevent OSA complications. Factors identified as predictor of OSA were: age, male sex, higher BMI, larger waist circumference, cardiovascular disease and alteration of diabetes control.

 


Chirea GABRIELA (Bucharest, Romania), Madalina DUMITRU
08:30 - 17:40 #11969 - The relationship between meteorological parameters and pneumonia.
The relationship between meteorological parameters and pneumonia.

In this study, we aimed to evaluate the relationshipbetween pneumonia and sociodemographic characteristics, tam kan sayımı parameters , meteorological parameters (temperature, humidity, precipitation, airborne particles, sulfur dioksit (SO2), carbonmonoksit (CO), nitritdioksit (NO2), nitrit oksit (NO), Nitric oksit (NOX)] in patients with the diagnosis of pneumonia in the emergency department.

Our study was performed retrospectively with patients over 65 years of age who were diagnosed with pneumonia. The meteorological variables in the days of diagnosing pneumonia were compared with the meteorological variables in the days without diagnosis of pneumonia. The sociodemographic characteristics, CBC and meteorological parameters (temperature, humidity, precipitation, airborne particles, SO2, CO, NO2, NO, NOX of the patients were investigated.

The mean age of 2606 patients was 77.7 ± 7.6 years and 53.2% were male. The most common lesion in imaging was lober pneumonia (45.3%). Patients' CURB 65 score was generally stage 1 or 2. 61.1% of patients had COPD and 38.7% of asthma. While the association of hemoglobin, leukocyte, lymphocyte, neutrophil, RDW, NLR and PLR levels with CURB 65 was significant (p <0.005); MPV and platelet levels were not associated with CURB 65 (p> 0.05). Although hemoglobin, leukocyte, lymphocyte, neutrophil, RDW, NLR and PLR levels were associated with hospitalization status (p <0.005); there was no correlation between MPV and platelet levels in admission (p> 0.05). When the temperature was high and low, the number of days consulted due to pneumonia was related to low air temperature (p <0,05). There was no relationship between the number of days referred for pneumonia and temperature when the temperature was moderate (p> 0,05). When the humidity was high, normal and low, the number of days admiting due to pneumonia was correlated with high humidity (p <0,05). In the periods when sea level pressures were high, the number of days referred for pneumonia was related to high pressure ratios (p <0,05). During the periods when PM10, NO, NO2, NOX and CO levels were high, the number of days referred for pneumonia was increased (p <0,05). There was no correlation between PM2,5 and SO2 levels and the number of days referred for pneumonia (p> 0,05) . On rainy days, the number of days referred to the hospital due to pneumonia was significantly higher (p <0.05). It was determined that temperature, NOX, NO2, CO value 4 days before and humidity and sea level pressures 2 days ago affected the number of patients admitted to the hospital due to pneumonia (p <0.05). Factors at other time periods were not associated with the number of patients admitted to the hospital due to pneumonia (p> 0.05).

As a result, climatic (temperature, humidity, pressure levels, rain, etc.) and environmental factors (airborne particles, CO, NO, NOX) were found to be effective on the number of patients admitted to the hospital due to pneumonia.


Suleyman Serdar TASCI, Cemil KAVALCI, Afsin Emre KAYIPMAZ (Ankara, Turkey)
08:30 - 17:40 #11153 - The retrospective analysis of the risk factors associated with ST Elevation Myocardial Infarction for romanian patients – our 5 year experience.
The retrospective analysis of the risk factors associated with ST Elevation Myocardial Infarction for romanian patients – our 5 year experience.

Background.

                Cardiovascular disease (CVD) remains the most common cause of death worldwide, with the 2013 Global Burden of Disease (GBD) study estimating that CVD caused 17.3 million deaths globally and  accounted for 31.5% of all deaths. CVD causes more than 50% of deaths in women in 29 countries, mostly in Central and Eastern Europe. In nine countries CVD causes more than 50% of deaths in men: Azerbaijan, Belarus, Bulgaria, Georgia, Montenegro, Romania, FYR Macedonia, Romania, Ukraine and Uzbekistan. In the las report for Romania between 1997 and 2009 the Romanian Registry for ST segment elevation myocardial infarction (RO-STEMI) included 19510 patients.

            Aim of our study was to investigate the demographic data and risk factors for ST-segment elevation myocardial infarction in Romanian patients in order to make some preliminary conclusions comparing the results in our clinic  during 5 years to the reported tendency in Europe.

Participants and methods.

            We included in this study, 250 patients presented, evaluated and treated to Emergency Clinic Hospital between January 2012 – January 2017, and we collected the demographic data (e.g. age, gender, region, etc.) and risk factors (e.g. diabetes, hypertension, obesity, smoking etc.). For AMI  we used the rapid test (e.g. GEM PREMIER 3500, SAMSUNG, SIEMENS, CONCILE, DPU-414 THERMAL PRINTER, URILYZER 100,GEM PREMIER 4000) and exhaustive analysis was made by the laboratory using different types of machines and technology (e.g. CELLTAC-F, VITROS_FS5.15, ACL TOP 500 etc.) to confirm the diagnosis. The data were statistically processed by SPSS ver. 20.

Results.

            In our study, we included 250 patients with cardiovascular / coronary disease. We notice that the ratio between men vs. women was 65.2% vs. 34,8%; in 2013 this ratio was modified (55,55% vs 44,45%). The age of the patients varied between 18 – 93 years. We observed for this five year that the age of oncet have decreased, 52,8% of patients have the age under 65 years. The most frequent risk factors remains smoking, hypertension, dyslipidemia and diabetes.

Conclusion.

            For our study we observed a trend increase in patients with hypertension and dyslipidaemia. Also, the age of onset is  decreasing year by year which should become an important signal for new prevention programs and studies.

 

Acknowledgements.

No potential conflict of interest relevant to this study. 


Oana Andrada ALEXIU (BUCHAREST, Romania), Amal Antonia ARNAOUTE, Bogdan Mihai OPRITA, Luisa Corina SIMION
08:30 - 17:40 #11299 - THE REVENGE OF A DEAD FISH.
THE REVENGE OF A DEAD FISH.

INTRODUCTION: Clinical presentation mimicking Aortic Dissection with hemodynamic compromise can be diverse with other pathological entities. Here we outline the importance of physical examination, targeted history taking and radiology in order to reach upto the root cause to describe the mechanics of fish bone migration.

CASE REPORT: A 53 year old male patient was brought with complain of left sided chest pain radiating to back was referred from private hospital with suspicion of Aortic dissection. On route patient had one episode of convulsion, vomiting followed by slurring of speech and breathlessness. On arrival, patient was conscious, tachycardic, hypotensive and tachypneic. On examination, air entry bilaterally equal, bilateral rhonchi present. Glasgow Coma Scale (GCS): E3V4M5, pupils: 2mm bilaterally equal reacting to light. Left upper and lower limb weakness was found. Electrocardiography showed sinus tachycardia, echocardiography was normal. Arterial Blood Gas showed compensated lactic acidosis. Troponin I was negative. Computed Tomography (CT) brain showed subtle hypodensity seen in right thalamus and right basal ganglia. Post imaging GCS dropped to E1V2M4, was electively intubated and put on ventilatory support. Post intubation Ryle’s tube was inserted which revealed around 500 ml of coffee ground colored aspirate. Chest X ray showed Ryle’s tube pushed towards right side. Magnetic Resonance Imaging of brain showed fresh left medullary, bilateral cerebellar, right thalamic and bilateral posterior cerebral artery infarcts. Upper gastrointestinal endoscopy showed mucosal erosion, loculated erythema and black patchy area in upper esophagus. Left upper limb distal pulse was feeble as compared to all other limbs. Contrast CT Thorax was considered suggestive of large pseudo aneurysm in poster superior mediastinum communicating with left subclavian artery with cardiothoracic esophageal perforation with changes of mediastinitis and foreign body in situ. A retrospective history revealed that patient had ingested fish bone twenty days back associated with throat pain which got relieved after two days. Patient underwent surgical repair and fish bone was removed.

CONCLUSION: Fish bones have a tendency to stuck in the pharynx and mucosal layer of the gastrointestinal tract due to their linear shape and sharp edges, and can then cause serious complications such as esophageal perforation, mediastinal abscess and left subclavian aneurysm. Penetration and extra luminal migration of ingested foreign bodies may cause severe vascular and suppurative complications, which left untreated can be fatal.


Dr Ketan PATEL (Ahmedabad, India), Anjali PATEL, Rignesh PATEL, Sakshi SEHGAL
08:30 - 17:40 #11240 - The role of EMS accessibility constraints on time to patient contact and failure to achieve return of spontaneous circulation after out-of-hospital cardiac arrest: a French multicenter prospective cohort.
The role of EMS accessibility constraints on time to patient contact and failure to achieve return of spontaneous circulation after out-of-hospital cardiac arrest: a French multicenter prospective cohort.

Background

Shorter emergency mobile services’ response times are associated with higher rates of return of spontaneous circulation in out-of-hospital cardiac arrest. Emergency mobile services’ response times are yet partially measured, as the time interval between the ambulance stop and patient contact (patient access time interval) remains little studied. Accessibility constraints may alter the walking path after the ambulance stops, therefore delaying patient access time interval. This supplementary time could lead to lower rates of return of spontaneous circulation in out-of-hospital cardiac arrests.

We aimed to compare the emergency mobile services’ patient access time interval upon the presence of accessibility constraints, and to evaluate its impact on the rate of return of spontaneous circulation in patients suffering from out-of-hospital cardiac arrest.

 

Methods

This was a multicenter prospective cohort study, involving major patients suffering from out-of-hospital cardiac arrest and undergoing advanced life support by physician-staffed emergency mobile services of a French urban area. Clinical data were collected according to the Utstein style. Accessibility data and time intervals were collected and measured using a population-based registry. All data were prospectively collected. We conducted a mixed multivariate logistic regression on the rate of return of spontaneous circulation.

 

Results

120 out-of-hospital cardiac arrests occurred during the study period (July 1st – December 31st 2016) in the district. 50% underwent advanced life support by emergency mobile services teams (n=60). A return of spontaneous circulation was obtained in 43% (n=26). Accessibility constraints were frequent (53%, n=58). Median patient access time interval was 2±1 min, and was higher in case of presence of accessibility constraints (3.3±2.0min vs. 1.8±1.1min, p<0.001). After mixed multivariate logistic analysis, time to patient contact was associated with lower rates of return of spontaneous circulation (p=0.03).

 

Discussion

Patient access time interval of emergency mobile services was linked to poorer outcomes in out-of-hospital cardiac arrests occurring in urban areas. It was longer when accessibility constraints were present. Our data suggest the need for corrective measures in urgent prehospital care (i.e. systematic data collection, typology and cartography of accessibility constraints).


Thierry DA CUNHA, Elise BRAMI, Jean MARTY, Charlotte CHOLLET-XÉMARD, Eric LECARPENTIER, Matthieu HEIDET (Créteil)
08:30 - 17:40 #11858 - The role of EMS responders in identifying human trafficking during the post-conflict period and mass gathering events.
The role of EMS responders in identifying human trafficking during the post-conflict period and mass gathering events.

BACKGROUND:

Human trafficking is a $150 billion industry worldwide with an estimated 20.9 million victims globally. During post-conflict periods, survivors are vulnerable to exploitation by traffickers. During mass gathering events, trafficking is at a high due to the chaotic event and accompanying increased demand. Trafficking activity may thus go unnoticed during large events such as the Olympics. Approximately one third of human trafficking victims are treated by medical providers. EMS responders are an ideal group to undergo training which could identify this vulnerable population. In the United States the Department of Homeland Security has initiated the Blue Campaign. The goal of Campaign Blue is prevention and protection. Once identified, assistance can be given to the victims, and the traffickers may be brought to justice.

METHODS:

An observational case-control study with EMS responders in the United States comparing 100 random EMS responders who did not undergo human trafficking identification training, with 100 EMS responders who have undergone training with the Department of Homeland Security Blue Campaign.

EMS responders include first responders, emergency medical technicians as well as paramedics. These groups are surveyed with the following questions:

1. Was human traffic training offered to the individual, specifically Campaign Blue. If not, was any other form of human trafficking identification training given, if so what training was received?

2. If training was given, does the responder have an increased awareness in identifying a trafficking victim?

3. Has the responder ever identified a trafficking victim?

4. If yes, what was done after the victim was identified?

RESULTS:

Study is underway. We hope to show that EMS responders who underwent training to identify human trafficking victims have more awareness, consequently enabling them to effectively identify a trafficked victim and respond appropriately.

DISCUSSION:

Human trafficking is overlooked in disaster response, and the purpose of this study is to show the importance of training EMS responders to increase awareness and knowledge in identifying potential trafficked victims. EMS responders may be the first contact of these victims during the post-conflict period as well as during mass gathering events. EMS responders are thus a vital cog in the recognition and identification of victims and it is important they receive training from initiatives such as Campaign Blue. 


Sneha CHECKO (Boston, USA), Brad NEWBURY, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11277 - The Role of fist pacing in witnessed asystolic cardiac arrest in patient with hemodynamically unstable bradycardia.
The Role of fist pacing in witnessed asystolic cardiac arrest in patient with hemodynamically unstable bradycardia.

Introduction :Bradycardic patients present unique challenges for the emergency department physician. In complete heart block a patient is at immediate danger of impendingasystole and requires immediate preparation for pacing.there is little evidence supporting fist or percussion pacing in cardiac arrest.Case report :In 3rd April 2017 ,at 22:35 A 54 –year old male patient presented to Alexandria Main University Hospital Emergency Department by  one of his relatives after being  disturbed level of consciousness for the last 7 hours . He had a history of hypertension and heavy smoker .On ED assessment: The airway was at risk ,  breathing : bilateral equal air entry with fine basal crepitation,respiratory rate : 35  breaths/min , oxygen saturation(poor signal),circulation : blood pressure 70/40 bilateral equalheart rate 20 beat/min , capillary refill time 4 second , The Glasgow Coma Scale was 12 ,random blood glucose 200 . exposure :congested neck veins with mild bilateral lower limb edema Arterial blood gases: 7.35-18-71-9.9-99% on mask oxygen. 12 lead electrocardiogarpy showed complete heart block with rate of 20 beat per min.Resuscitation with six doses of 0.5 atropine with no response, after the first two doses the patient was planned for emergency Trans venous pacing (No immediate availability of transcutaneous pacing). During preparation, the dopamine infusion was started at 10 mic / kg/min still no response .patient was intubated on persistent shock, Central venous Cather was inserted (Right internal jugular), and central venous pressure was measured (33-34).His monitored rhythm becomes asystole, patient stopped breathing and had no central pulse instead of start CPR started fist pacing rate (60 / min) for 1.5 min The patient had peripheral pulse and was taking during fist pacing .then recovered . After 4 min the patient developed second attack of a systole cardiac arrest after 2 min of fist pacing was recovered. Trans venous pacing (left subclavian sheath) was inserted (rate 70 ) . the patient self-extubated and adrenaline was weaned after successful trans venous pacing. The follow up assessment :the airway :patent ,clear, secure , respiration 32 breath / min  , oxygen saturation 98% with blood pressure 120/70  bilateral equal heart rate :70 beats /min capillary refill time 3 second ,arterial blood gases :7.45-23-159-16-99%.the laboratory data  were unremarkable. The patient admitted to the CCU and the Trans venous pacing was removed 2 day later.coronary angiography was performed, it revealed the presence of a systolic narrowing (myocardial bridging) of the left anterior descending artery,There was a stenosis of the right coronary artery. Discussion:Recent studies have demonstrated that the artrioventricular conduction blocks, sudden death can be of  a complication of  myocardial  bridges . Complete heart block is the most serious type of AV heart block,Percussion pacing an almost forgotten procedure for hemodynamically unstable bradycardias.


Dr Muhammad ABDULHALEEM HAMADA, Mostafa Yousry Shaban SOWAILAM, Sara Mohamed Kamal El-Din ELTAYEB (alexandria, Egypt), Salah Mohamed ELTAHAN
08:30 - 17:40 #11926 - The secret is in the heart.
The secret is in the heart.

- Reason for referral: Loss of right arm force, dysarthria and bradypsychia during two minutes.

- Previous medical history: Intolerance to aspirin and Non-Steroidal Anti-Inflammatory Drug. Pathological antecedents for Migraine with aura

- Patient profile: A 49-year-old woman. While the patience was eating she began a clinic of dysarthria and loss of strength and sensitivity from the right arm during two minutes, in addition the inability to speak. No headache, no loss of consciousness, no abdominal pain, no cough or expectoration.

-  Physical examination:

No fever. Hemodynamically stable.

Conscious and oriented, isocoric and normoreactive pupils. Cranial pairs without alterations. Equal strength and sensitivity in all extremities. Normal cardiac auscultation. Preserved vesicular murmur. Abdomen without alterations.

- Routine investigations:

            + ECG: Normal

            + Chest X ray: Normal

            + Blood count: Normal. Basic biochemistry: Normal. Coagulation: Normal. Urinalysis: Normal.

            + Cerebral CT scan without alterations

- Differential diagnosis in the emergency room: transient ischemic attack vs epileptic seizure.- Evolution: We called the neurologist to to request his assessment. He did a Neurosonology of supra aortic trunks that was normal. The neurologist follows the patient in an appointment in the following days because the patient did not want to be admitted to the hospital.

The electroencephalogram and the echocardiogram were normal. The right – left short circuit study showed the presence of massive signal passage  suggestive of fibrodysplasia ossificans progressiva

- Diagnostic orientation: Patent Foramen Ovale (PFO). This diagnostic could explain the symptoms that had the patient in the first day.

- Treatment: The neurologist prescribed clopidogrel 75 mg, a pill in a day.

- Evolution after the treatment: The patient improved of the symptomatology. She has not presented any clinical signs of paralysis during the last 6 months.


Juan Ortega Pérez, MERITXELL VIDAL BORRÀS, ELISA ALBACAR RIBA, (Palma de Mallorca, Spain)
08:30 - 17:40 #11248 - The social media researches in emergency medicine journals: a literature review and trend analysis.
The social media researches in emergency medicine journals: a literature review and trend analysis.

Background:

Social media (SoMe) is a rapid growing filed in the past ten years with wide application on networking, information exchange, education, and trend analysis. The application of SoMe in emergency medicine (EM) researches are not studied.

This study aims to evaluate the application and impact of SoMe in EM researches.

 

Methods:

Design: This study was an observational study.

Setting: All of the data were collected from SciVerse Scopus database.

Type of participants: All of the articles published in EM journals (2015 Journal Citation Reports) indexed with key words of Facebook, Twitter, Google, Blogger, YouTube, Instagram, Reddit, Tumblr, Weibo, Pinterest, blogging, webcast, webcasting, webcasts, podcast, podcasts, podcasting, web 2.0, social media, social networks, and social networkingwere enrolled.

Data Collection: A computerized literature search was conducted in November 3, 2016. Two emergency physicians reviewed the publication independently to exclude articles not focus on SoMe and classified the SoMe related publications according to the research fields. We collected data on publications including publication year, journal, document type, author’s name, affiliation, and country for further analyze.

Data Analysis: The demographic data were analyzed by descriptive statistics. Linear regression was used for trend analysis.

 

Results:

A total of 861 publications were retrieved from initial search, 762 publications were excluded due to the study focuses were not on SoMe. A total of 99 publications were enrolled for further analysis. The publication number increase from 1 in 2004 to 28, 18 in 2015, 2016 respectively. The increasing trends of publications number were 1.73 (95%CI 1.00-2.46). The leading SoMe research fields were education (69), research/publication (7), EMS (5). The major application were physician education (70), collecting data (12), patient education (6). The leading journals publish SoMe related articles were Annals of Emergency Medicine (22), Emergency Medicine Australasia (17), Academic Emergency Medicine (11), and Emergency Medicine Journal (11). The leading countries were the United States (52), Australia (15), Canada (12).

 

Conclusions:

The SoMe EM researches were increasing in the past 10 years. Education is the major application and research field which reflect the leading role of free open access medication education (FOAMed) in EM. The U.S. is the hub of SoMe EM researches. Applying SoMe in more diverse EM subspecialty indicated future research directions. 


Ching-Hsing LEE, Pei-Chen JUAN (Taoyuan, Taiwan)
08:30 - 17:40 #11001 - The status of early protein intake in septic patients and evaluation on the correlation between protein intake and clinical consequences.
The status of early protein intake in septic patients and evaluation on the correlation between protein intake and clinical consequences.

Background & Aims
Systemic inflammatory response developing in septic patients causes the facilitation of catabolism and amplified proteolysis through stress hormones as well as inflammatory mediators, and thus causes consequences such as delayed wound healing, increased days of infection, and the increase of inpatient days as well as mortality. The A.S.P.E.N. guidelines suggested the daily allowance of protein to be 1.2~2.0g/kg in critically ill patients including septic patients, but a study has lately reported that high protein intake can be harmful in early sepsis. The present study investigated the status of early protein intake in early sepsis at a tertiary general hospital and analyzed the correlation between protein intake and clinical consequences.

Methods
A retrospective cohort observational study was performed using electronic medical records from June 2012 to July 2015. The study subjects were early sepsis patients aged 18 to 80 who stayed in the surgical ICU for more than 3 days and fasted for more than 4 days. The status of 7-day protein intake included in intravenous nutrition was investigated, and the subjects were categorized into two groups according to the protein intake on the 4th day after the diagnosis of sepsis. Based on these two groups, the association with mortality, length of ICU hospital stay, the total length of hospital stay, and duration of mechanical ventilation was examined.
Results
In the entire cohort group of 60, the median protein intake on the 4th day after the diagnosis of sepsis was 0.98 g/kg, and the average length of ICU stay, entire length of hospital stay, duration of mechanical ventilation, and mortality were 8.2(3~60), 48 days (9~127), 9.5 days (0~77), and 25%, respectively. As a result of logistic regression analysis including the protein intake group, mortality had no association with sex, age, weight, BMI, calorie intake, and entire length of hospital stay, as a result of linear regression analysis. Protein intake also had no association with age, body weight, BMI, and calorie intake.
Conclusions
The protein intake in early sepsis was lower than the daily protein allowance recommended by ASPEN, and this study showed no significant variation in length of ICU stay, entire hospital stay, duration of mechanical ventilation, and mortality according to the protein intake in early sepsis.


Jung-Won HWANG, Inae SONG (Seoung Nam si, Republic of Korea)
08:30 - 17:40 #11470 - The suicide in the elderly: the emergency room as the last ring in a chain that should be broken before.
The suicide in the elderly: the emergency room as the last ring in a chain that should be broken before.

Suicide in older adults is a phenomenon often underestimated, while in fact in young people attempted suicide predominate, in the elderly completed suicide is prevalent, with a higher rate in male. In elderly depression is the primary risk factor for suicide, anyway the presence of other diseases, psycho-social factors and bereavement are also associated. Clinicians often under-diagnose and under-treat these conditions among older adults, in part because of non-traditional presentations and in part because diagnosis can be complicated by concurrent cognitive impairment.

A 89-year-old patient, known for COPD, incipient cognitive decline, depression, a recent hospitalization for a pulmonary septic shock (6 weeks before) is brought to our emergency room because of deteriorating general conditions. The same morning the patient didn’t open the door to home-care nurse. When finally the home-care staff opened the door, the physician found the patient partially confused and asthenic and decided to bring him to our ED.

The patient reported the absence of any respiratory, urinary, or abdominal symptoms. We found the patient in decayed general conditions, oriented in space, partially oriented in time, no other abnormalities during neurological evaluation were observed. Vital signs: blood pressure 110/65 mmHg, heart rate 85/minute, O2 saturation 97%. Cardiac and abdominal examination were normal. At chest auscultation we observed some crackles at the two bases. Patient home treatment included: aspirin 100 mg, mirtazapine 30 mg, inhaled steroids, anticholinergic and LABA.

Laboratory tests showed mild CRP elevation without leukocytosis. Chest radiography highlighted a possible left posterior-basal infiltrate and minimum bilateral pleural effusions.

Only after a long exchange the patient reported that the night before he took 7 tablets of zolpidem 10 mg for suicidal purpose. Suicidal ideation has been already reported during last hospital admission, for this reason a psychiatric consultant introduced treatment with mirtazapine.  On supplementary questioning, the patient revealed multiple recent stressors, including functional impairment, loneliness and fear of becoming a burden to his family.

The patient was evaluated by the ED’s physician and geriatrician and admitted to a psychiatric clinic.

Regardless of screening practices, clinicians should be aware of suicide risk factors among elderly. Suicide prevention for older adults poses unique challenges because these individuals are more likely to employ advance planning and less likely to ask for help. For this reason the role of general practitioner in the assessment and management of suicide risk is mandatory. However, there remains a need to improve the identification of suicidal ideation among older adults and systematic screening protocols may be beneficial. In our emergency department we started a closed collaboration with geriatricians who have the tools to investigate and evaluate properly all this aspects


Angelica VACCARO (Fort De France, Martinique), Clara GIRARDI, Emanuela ZAMPROGNO
08:30 - 17:40 #11519 - The tell-tale heart.
The tell-tale heart.

To describe an uncommon side effect of quetiapine abuse in 45 year-old woman

 who assumed 13 tablets of quetiapine for suicidal purpose

A 45 year-old woman, guest of a private clinic, was brought to our ED after taking, about an hour before, 13 tablets of quetiapine 100 mg.

At the admission GCS was 14, with rhythmic heart activity, no chest pain. Vital parameters were normal. The first ECG performed, 5 minutes after the arrival, was normal.

15 minutes later, the patient complained of retrosternal pain with mild dyspnoea. A second ECG showed a three millimeters ST elevation in DII,  DIII and aVF.

A NaHCO3 infusion was established (150 mEq in 30 minutes + continuing infusion) until a serum  pH of 7,50 was reached, with a rapid improvement of clinical conditions, and ECG normalization 90 minutes later. The patient was subjected to gastric lavage, and serum alkalinization  was mantained for 12 hours without signs of cardio-or neurotoxicity during clinical observation.

In quetiapine overdose ECG abnormalities, such as  QRS  or QTc  prolongation, are very uncommon. Six to seven percent of patient may experience tachycardia.

Quetiapine is an atypical antipsychotic approved by the FDA to have minimal effects on the QT interval at therapeutic doses. The lengthening of the QT interval in association with overdose of quetiapine has already been described; in other cases has been described only a lengthening of the PR interval, ST depression or mild supraventricular tachycardia. However, to the best of our knowledge, ST-segment elevation has never been described. Despite the threatening aspect of the ECG, the absence of  hyperkinetic or hypokinetic arrhythmias in the case we observed, seems to confirm the value of literature related less elevated arrhythmic risk of quetiapine than those of the first generation

In this case report we also want to point out how these changes have completely normalized without the use of cardiac-specific drugs, but only with sodium bicarbonate infusion.


Giorgio RICCI, Gianni TURCATO, Massimo ZANNONI (VERONA, Italy), Chiara BOVO, Lucia ANTOLINI
08:30 - 17:40 #11948 - The trend of legislation in Individual states in the United States on the use and availability of Naloxone to combat deaths from opioid overdose.
The trend of legislation in Individual states in the United States on the use and availability of Naloxone to combat deaths from opioid overdose.

Background

Opioids are an increasing public health threat and have become a leading cause of non-injury death in the United States of America. Approximately 1 in 8 of those dying in the 15-30 age group are dying from opioid overdose.  The Centers for Disease Control reports that there were 33,000 deaths from heroin and prescription opioids in 2015, more than any year on record.  Nearly half of all opioid overdose deaths involve a prescription opioid.  The United States and Canada are among the highest prescribers of opiates in the world. The current opiate crisis has been labelled a "clear and present danger" to the population of the United states and been declared a public health emergency by some. Prescription opioid sales have been rising consistently since the year 2000 and with the addition of very potent illicit opiates such as fentanyl and carfentanyl onto the streets there is a growing threat to first responders themselves who risk absorbing such substances through contact with powders. Canada has introduced a very successful take home naloxone program which is estimated to have saved 7,000 lives in recent years. A multifactorial legislative policy and systems-level harm reduction strategies and interventions based approach in Canada is yielding dividends. Naloxone is on the WHO list of essential medicines and acts by reversing the effects of opioid overdose with minimal side effects.

Objectives

To look at how legislation has changed, for naloxone overdose prevention, throughout states in the United States of America.

Methods

A literature and legislative review was conducted for information regarding opioid policy and legislative strategies using databases such as pubmed, ebscohost, CINHAL, google scholar and reference scanning of the literature.  Articles were excluded based on relevancy, non-English text.

The Policy Surveillance Program an online database, a legal mapping tool was used to track legislation for naloxone from the year 2000-2016.

RESULTS

In 2001 New Mexico was the single state which had a naloxone access law, this had changed to 46 states by 2016.

In the year 2016,

- In 15 of the 46 States a lay individual could be found criminally liable for possessing naloxone without a prescription.

- 41 states authorized prescription of naloxone to 3rd parties, however 3 of these states required the individual to participate in a naloxone program.

- 40 States allowed prescription by standing order

- in 32 States prescribers have immunity from criminal prosecution for prescribing, dispensing or distributing naloxone to a layperson

Conclusion

Considerable work is required by Physicians to lobby their legislative assemblies to introduce legislation facilitating wider access to naloxone among lay/community first responders and law enforcement officials to save lives in these "diamond" minutes.


Michael MOLLOY, Sukhshant ATTI (Boston, MA, USA), Maryam ARSHI, Ritu SARIN, Amalia VOSKANYAN, Gregory CIOTTONE
08:30 - 17:40 #11144 - The trend of smoking epidemic.
The trend of smoking epidemic.

Introduction: Smoking is a common risk factor for the four main noncommunicable diseases: cardiovascular disease, cancer, diabetes and respiratory diseases.

Objectives: To recognize the trend of smoking epidemic.

Materials/Methods: This study is a scientific literature review.

Results: Smoking kills every year around  6 million people worldwide. Most of the deceased persons had actively consumed tobacco, but among the deceased were also 600,000 non-smokers exposed to tobacco smoke. The regions with the highest proportion of deaths attributable to tobacco are the Americas and Europe where tobacco has been consumed for longer. WHO estimates that the mortality attributable to tobacco in the Region is 14% in adults aged 30 years and over (15% in men and 14% in women). In addition to the catastrophic consequences for health and the direct and indirect costs of treating diseases, smoking leads to enormous economic costs not only for smokers, but for society as a whole. Some of these costs are reflected in the fact that one in four smokers will die of working age, while many survive will see their income reduced due to the loss of days of work due to illness or disability. The impact of tobacco on the environment has not been recognized to the same extent. However, this impact occurs at many stages of the environmental tobacco life cycle. The tobacco control programs with the greatest impact are those that include interventions in the population aimed at discouraging young people from starting to smoke and at the same time supporting current smokers to stop smoking. It is important that countries ensure the full and coordinated implementation of all provisions of the WHO Framework Convention on Tobacco Control.

Conclusion: In summary, for tobacco control programs to have greater impact, interventions are needed in the population not only to discourage young people from starting to smoke, but also to encourage current smokers to quit smoking. Although the ultimate goal of ending the smoking epidemic is that young people do not start smoking, the heavy burden of mortality due to tobacco in the first half of this century can only be avoided if those who are currently smoking quit smoking. According to WHO and other scientific bodies, there is insufficient scientific knowledge to assess the differences in the risk associated with new tobacco products and products already known in terms of composition, exposure, toxicity or harm.


Llambi SUBASHI, Brunilda SUBASHI (Vlore, Albania), Denada SELFO, Rozeta LUÇI, Glodiana SINANAJ, Erilda RUCI, Adela HAXHIRAJ, Erion PANAJOTI
08:30 - 17:40 #11337 - the two faces of MDMA; multiorgan dysfunction versus mild agitation.
the two faces of MDMA; multiorgan dysfunction versus mild agitation.

The Two Faces of MDMA: Multi-organ Dysfunction versus Mild Agitation

 

This case focuses on two extremes of presentation following MDMA use, in two teenage girls, both with exposure to the same drug batch and dosage.

Both girls had used 10 crystals of MDMA prior to presentation.

Case A presented with mild agitation and extremes of emotions, displayed by crying followed by laughing and euphoria. All medical observations were within normal limits and she was discharged following a period of observation.

 

Case B presented with a GCS of 6, temperature of 42.1 degrees, blood glucose of 1.1, bicarbonate of 10.1 and initial agitation, which progressed to generalised tonic-clonic seizures.

At presentation, she was treated acutely for the malignant hyperthermia with cold intravenous fluids and ice packs. She was then intubated, ventilated and given midazolam to terminate the seizures. Her blood glucose was corrected with a bolus of IV dextrose and her bicarbonate corrected with a sodium bicarbonate infusion.

Further investigations revealed an initial creatinine kinase of 19,664 and she was noted to have rhabdomyolysis with myoglobin present in her urine.  An initial CT showed mild oedema.

She was transferred to PICU for continued care, where her CK rose to 86,361{max}, her creatinine reached 283 and ALT 2278. She had veno-venous hemofiltration for her renal failure, received multiple blood products for her liver failure and remained intubated for 10 days. Echocardiogram showed a structurally normal heart with dilated IVC and an EEG showed diffuse slowing indicative of widespread cortical dysfunction possibly due to recent sedation. An MRI scan showed:  improvement in swelling from previous CT scan with some cerebellar cortical signal changes likely due to hyperpyrexia/MDMA. 

Upon extubation, she had normal gross neurological function with no apparent expressive or receptive aphasia; however she demonstrated some mild weakness to dorsiflexion bilaterally but worse on the left and some cerebellar signs including dysdidokinesia, intention tremor bilaterally, past pointing, horizontal gaze nystagmus and ataxic gait.

MDMA is a potent and selective serotonin neurotoxin, whose use is fast becoming more popular in adolescents, hence the importance of highlighting its long term and possible fatal effects.

Many cases have been reported in relation to MDMA use with toxicity and side effects, however with this case, we aim to discuss hyperpyrexia and the extensive multi organ involvement, following the use of MDMA and how its presentation can differ in each individual.

References

 BMC Pharmacol Toxicol. 2016 Jun 28;17(1):28. doi: 10.1186/s40360-016-0070-0.


Fiona WRIGHT (Cambridge, United Kingdom), Olajumoke OSOFISAN, Nickolaos CHOLIDIS, Soe THAN
08:30 - 17:40 #11173 - The use and prescription of oxygen in the Emergency department.
The use and prescription of oxygen in the Emergency department.

Introduction: Oxygen is the most commonly used medicine in the emergency department and can be lifesaving in treatment of hypoxaemia. As per the British Thoracic Society (BTS) guidelines, oxygen should be prescribed to achieve a target saturation of 94% - 98% for all acutely ill patients or 88% - 92% for those with hypercapnoeic respiratory failure1.

However, careless use of oxygen by incorrect administration, over oxygenation or failure to monitor the patient on oxygen can be life threatening. These problems can be avoided by doctors correctly prescribing oxygen.

Objectives: To assess the use of oxygen and it's prescription in patients coming to the emergency department resuscitation room.

Methods: This is a prospecive study carried out initially in November 2015 and re-audited in November 2016 for two week periods in the emergency department of Our Lady of Lourdes Hospital; to assess the number of patients prescribed oxygen. Inclusion criteria were all adult patients brought to the resuscitation room requiring oxygen

In the first cycle, 40 patients were audited (17 males and 23 females). Majority of the patients presented with acute exacerbations of COPD. Other presenting conditions were acute abdomen, cardiac chest pain, trauma, gastrointestinal bleeding, anaphylaxis and CVA. 

Following this, education sessions were given prior to conducting the second cycle. During these education sessions, the dangers of inadvertent oxygen therapy and the importance of correctly prescribing oxygen were emphasised.

With a possible change in practice, the second cycle of the audit was conducted with 40 patients (20 males and 20 females). They presented with mainly respiratory issues as well as gastrointestinal, cardiac, neurological, trauma and general medical complaints.

The results of the two cycles of the audit were compared and then both were compared to the gold standard as set by the BTS in 20081.

Results: 1st cycle: 35% of patients were administered oxygen inappropriately with only 2.5% of patients prescribed oxygen. 

2nd cycle: 40% of paients were administered oxygen inappropriately. There was an improvement in the intervention following appropriate education with 20% of patients prescribed oxygen. The results showed an increase in oxygen prescription between the 2 arms of the study, however an unacceptable number of patients continue to receive oxygen unnecessarily. The standard for oxygen prescription is much below that outlined by the BTS in which 100% of patients receiving oxygen should be prescribed oxygen prior to treatment or after initial treatment in emergency settings.

Conclusion: Our study showed improvement in current practices of prescribing oxygen with appropriate educational interventions. Further audit required in preparation for the review of the BTS 2008 guidelines due in 2017.

References: 1. O'Driscoll BR, Howard LS, Davison AG 2008. Guideline for emergency oxygen use in adult patients. British Thoracic Society Emergency Oxygen Guideline Group.


John Paul OFFIAH (Dublin, Ireland), Zachery TAN, Sanjay KUMAR, Conor KELLY, Conor EGLESTON
08:30 - 17:40 #11516 - The use of sodium thiosulfate in sodium hypochlorite ingestion.
The use of sodium thiosulfate in sodium hypochlorite ingestion.

To study the effectiveness of sodium thiosulfate in the ingestion of caustic were evaluated 100 patients admitted at Emergency Department by ingestion of sodium hypochlorite solution from January 2009 to August 2016.

In 68 subjects the contact occurred by accident, while in the remaining 32 the exposure to the substance was found to be associated with suicidal intent.

All patients were subjected to supportive therapy and endoscopic examination performed at admission and after 12 and 36 hours after ingestion.

In subjects in which the ingestion of the substance was accidental, the amount of sodium hypochlorite was found to be 10-30 ml and at a rate not exceeding 5%. In cases of intentional exposure, the patients ingested 50-100 ml of hypochlorite, in 27 at a concentration of 5% and of 15% in 5 cases.

75 patients underwent only supportive care, decision given the small amount of the substance allegedly ingested. Of these, at endoscopy performed, 13 had gastric and esophageal lesions from mild to severe, 9 significant edema of the mucosa and esophageal stenosis, 3 patients were perforated. In 25 subjects sodium thiosulfate in oral suspension was administered, presumably at the same dosage of sodium hypochlorite ingestion: in 17 cases, intervention was timely and was achieved within 30 minutes of ingestion, in 8 cases between 30 and 90 minutes ingestion. Endoscopy examination subsequently carried out in 17 cases in which the administration of sodium thiosulfate was within 30 minutes, the local symptoms was very low: the patients complained only moderate pain on swallowing and chestburn. Above all, at the follow up controls, performed until six months after the event, there were no significant sequelae. As for the 8 patients who received the antidote from 30 to 90 minutes, in 5 the amount of sodium hypochlorite was found to be ingested 50-80 ml of 5%: in these cases discrete erythema of the oropharyngeal mucosa and oesophageal or mild edema of the upper portion of the esophagus was detected and required medical supportive therapy, in 3 cases the amount of sodium hypochlorite ingested was greater than 100 ml of 15% and this required the placing of a stent in emergency temporary and a follow-up endoscopic surgery of esophageal dilatation. 


Giorgio RICCI, Massimo ZANNONI (VERONA, Italy), Gianni TURCATO, Lucia ANTOLINI, Chiara BOVO
08:30 - 17:40 #11323 - The usefulness of point of care testing analysis in the Emergency Department.
The usefulness of point of care testing analysis in the Emergency Department.

In the last few years, for emergency medicine, more and more the medical decisions, regarding admission, discharge and medication are based on lab results. Point of care testing (POCT) in the Emergency Department (ED) is becoming a need for the doctors.  

POCT instruments are used every day in our ED for biomarkers determination, such as cardiac biomarkers (CK-MB, troponine I, NTproBNP etc.), sepsis biomarkers (presepsin), blood gas analysis (PaO2, PaCO2, pH etc.) and also for blood tests – blood cell count, biochemistry and urine tests (toxicology).

Methods & Discussions

We made a comparison between the blood test results obtained from 200 patients on POCT instruments (biochemistry) and the blood tests obtained in the Central Laboratory of the hospital.

Conclusion

The final result was a little difference between the 2 lab tests, but with no statistically significance.  

Acknowledgements.

No potential conflict of interest relevant to this study. 


Dr Mihai TOMA (Bucharest, Romania, Romania), Caius Bogdan TEUSDEA
08:30 - 17:40 #11417 - The utility of qSOFA criteria in the risk-prediction of patients presenting to the emergency department with suspected sepsis: a pilot prospective observational study.
The utility of qSOFA criteria in the risk-prediction of patients presenting to the emergency department with suspected sepsis: a pilot prospective observational study.

Background: The 2016 definitions of sepsis suggested use of the quick Sepsis-related Organ Failure Assessment (qSOFA) score as a physiological bedside test for identifying patients with suspected infection at high risk of poor outcomes. However, there remains uncertainty about the suitability of using qSOFA for the risk-stratification of Emergency Department (ED) patients.

Objective: We aim to prospectively validate qSOFA among ED patients, and compare its risk-prediction performance to that of the already established Systemic Inflammatory Response Syndrome (SIRS) and National Early Warning Score (NEWS) criteria.

Methods: We prospectively screened all patients attending the ED for suspected infection, over nine 8-hour shifts. Presenting physiology was recorded for risk scoring. The qSOFA, SIRS and NEWS were compared in their ability to predict poor patient outcomes, defined as 72-hour mortality or ICU admission.

Results: 79 patients were enrolled in the study, only 6 of which had poor outcomes. For predicting poor patient outcome, a qSOFA≥2 had a sensitivity of 0.67 and a specificity of 0.89, compared to 0.83 and 0.40 for SIRS≥2, and 1.00 and 0.44 for NEWS≥3.

Conclusions: qSOFA is a higher specificity sepsis risk-prediction tool than SIRS and NEWS, but comes at the cost of a reduced sensitivity. The potential clinical risk of this reduced sensitivity suggests that qSOFA has limited utility as a bedside sepsis risk-prediction tool in the ED. Low sample size and few observed outcome events limit the generalisability of our results.


Hugo GALE (Reigate, United Kingdom), Deepankar DATTA, Timothy WALSH
08:30 - 17:40 #11961 - The value of systolic time intervals (STI) in the diagnosis of heart failure (IC) in patients admitted to emergency for acute dyspnea.
The value of systolic time intervals (STI) in the diagnosis of heart failure (IC) in patients admitted to emergency for acute dyspnea.

Purpose :Diagnosis of AHFin dyspneic patients is a frequent challenge for ED physicians. Measurement of STIs could be a useful method for the distinction between dyspneic patients with and without AHF and can measure non-invasively. We evaluate the diagnostic performance of STIs to detect AHF in acute dyspneic patients.

 

Methods :In this prospective cohort study , all dyspneic non traumatic patients  aged ≥ 18 years were included. We exclude acute coronary syndrome, pericardial effusion, serious arrhythmia, pace maker and severe mitral valve disease. AHF is defined on the basis of clinical findings, NT pro-BNP >1200 pg/ml and echocardiographic criteria. For each patient demographic and clinical data were collected at ED admission and phonoelectrocardiography was performed to measure the pre-ejection period ( PEP) and the left ventricular ejection time ( LVET ) . Comparison between patients with AHF (AHF group ) and patients without AHF ( non AHF group) was done using standard tests. Discrimination of the different STIs was assessed by the area under ROC curves.

Results: 658 patients were included (402 AHF group and 256 non AHF group). The LVET and the PEP/ LVET ratio are increased in the AHF group while the LVET is decreased with a statistically significant difference (p <0.001). The AUC for PEP, LVET and PEP/LVET ratio was respectively 0.74, 0.72 and 0.78. The sensitivity and specificity of the PEP/LVET for a threshold of 40 are respectively 64% and 82%. For patients with a NT pro-BNP value in the gray zone (n = 107), the PEP/LVET ratio increases the discriminative value of NT pro- BNP alone from 1.8 to 3.6. Conclusion:Measurement of STIs obtained by a non-invasive method in patients presenting to the ED with acute dyspnea had a good diagnostic performance for the detection of AHF especially when the NT pro-BNP values are in the gray zone.


Kaouthar BELTAIEF, Noussaiba AZAIEZ, Nader BEN OTHMEN (Monastir, Tunisia), Zied EZZINA, Malek ECHEIKH, Med Amine MSOLLI, Med Hbib GRISSA, Wahid BOUIDA
08:30 - 17:40 #10910 - The White Plan: assessment of the level of training and knowledge of staff.
The White Plan: assessment of the level of training and knowledge of staff.

Introduction: The goal of a white hospital plan is to reconfigure the facility and ensure a rapid reorganization, enabling the provision of care to be expanded and adapted to meet a unique and exceptional demand, All personal and technical means. We sought to clarify the level of training and knowledge of staff in this study.

Material and method: We carried out a one-time, single-center survey. Four services were selected for their strong involvement in case of unexpected influx; The emergency department, multi-purpose resuscitation, SSPI and the operating room. All staff present on a randomly selected day were asked to answer a questionnaire. The answers to the questions were dichotomous closed type yes or no.

Results: A total of 153 people were surveyed (38% IDE, 10% senior doctor, 17% administrative agent, 8.5% students) .19% were under 30 years of age, 53% White of the HNFC1, 20% had already participated in exercises, 29% had received training in this area (48% via CESU2). In case of triggering 59% are aware of their mission (22% for the SSPI staff versus 85% of the emergencies). For the criterion "knowledge of the White Plan", there is a total lack of knowledge of students (interns and FDI students) compared to other categories (69% versus 31%, p = 0.05). For the criterion "level of training" it is noted that people under 30 years are significantly less trained (7% versus 34%).

Discussion: The overall level of knowledge and training in our sample seems encouraging, probably biased by the profile of the chosen staff. Our study highlighted a lack of knowledge particularly among hospital students and young nurses. Initial training seems to be completely overlooked in this area (84% want further training), giving way to often anxiogenic ideas.

Conclusion: Information and training efforts should be continued, in particular towards the youngest staff, with, of course, more regular and sustained implementation of simulation exercises, thus making it possible to validate the procedures and to make them available Adapted patches in real time.

1-HNFC: Hospital Nord Franche Comté /2-CESU: Center for Emergency Education


Hakim SLIMANI, Charles Eric LAVOIGNET, Luc SENGLER (Belfort)
08:30 - 17:40 #11809 - Thermography as a diagnostic tool for deep vein thrombosis in non-traumatic swollen lower extremity, a cross sectional study.
Thermography as a diagnostic tool for deep vein thrombosis in non-traumatic swollen lower extremity, a cross sectional study.

Background

Lately the advancement of thermography, has made it possible to measure temperature of the surface area of the body and not only for a single spot. This opens for the possibility to use surface temperature clinically for diagnosing.

Today a lot of patients are sent home without a diagnosis when DVT is ruled out. DVTs affects the blood flow locally and therefore should be detectable with thermography. Therefor thermography may be able to diagnose patients who otherwise would be send home without a diagnosis.

Objective

The aim is to investigate the thermographic differences that evolve during episodes of deep vein thrombosis (DVT) in the lower extremity.

We hypothesize that there is a significant difference for the maximum temperature differences between the affected leg and the unaffected leg depending on the cause for the swelling.

The null hypothesis being there is no significant difference for the maximum temperature differences between the affected leg for DVTs. 

Methods

The study was conducted from October to April 2017 at the emergency departments of Odense University Hospital and the Hospital of South West Jutland in Denmark

The participants recruited were patients presenting with unilateral swelling of the lower extremity. To be eligible for this study participants had to be at least 18 years old and be willing and able to sign a consent form. The patient also had to be assigned a room with controlled temperature of 22±2C° .

A standardized thermal image was taken for each region (upper leg, knee, lower leg, ankle and foot) bilaterally and from both an anterior and posterior angel (except the foot). The outcome was the final diagnoses set by the attending.

Using the unaffected leg as baseline, a temperature gradient (delta t) for the maximum temperature between the legs was calculated for each region. A t-test for DVT where conducted, using the unknown causes for unilateral swelling as baseline.

Results

We screened 116 patients, 5 refused to participate and 11 were excluded due to uncontrolled room temperature. One patient was excluded due to language barrier and 99 patients were included. Fifty-four (55%) were women and the median age was 61.5 (24-96) years. Thirty-five patients had an unknown cause of swelling. Twenty-five had a DVT, 16 erysipelas, six a Baker’ cysts, three arthritis, 12 thrombophlebitis, one tendinitis and one a diabetic foot ulceration.   

The anterior angle of the foot showed a significant negative difference in the mean delta t for DVTs compared to the baseline -1.22 (-2.41;-0.03). The posterior angle show a positive difference in the mean for the knee 0.79 (0.21;1.36), lower leg 0.88 (0.04;1.72) and ankle 1.64 (0.62;2.65) compared to the baseline.  

Conclusion

For the posterior angle of the knee, lower leg and ankle DVTs shows a significant increase in temperature compared to the unilateral leg, compared to people with unknown cause for swelling. A significant decrease was found for anterior angle of the foot.


Morten LORENTZEN (Odense C, Denmark), Nadia Hejgaard BENDIXEN, Mikkel BRABRAND
08:30 - 17:40 #10603 - Thoracic Intestinal Obstruction , Rare Case Presented in ED.
Thoracic Intestinal Obstruction , Rare Case Presented in ED.

           The abdomen is the normal container for intestine but in special situation the intestine can be passing to thoracic cavity through diaphragmatic hernia. In this abstract we will describe a case of iatrogenic diaphragmatic hernia for colon interposition which had obstruction and dilatation as infrequent case presented in emergency department (ED). Late complication after 20 years .


Dr Islam ELROBAA (Al wakra, Qatar), Rana ELSAYED, Muayad AHMAD, Mowahib OSMAN, Hani ALDULIMI
08:30 - 17:40 #11569 - Thoracic Intestinal Obstruction, Rare Case Presented in ED.
Thoracic Intestinal Obstruction, Rare Case Presented in ED.

The abdomen is the normal container for intestine but in special situation the intestine can be passing to thoracic cavity through diaphragmatic hernia. In this abstract we will describe a case of iatrogenic diaphragmatic hernia for colon interposition which had obstruction and dilatation as infrequent case presented in emergency department (ED). Late complication after 20 years. This case showed male patient young 22 years old presented as second visit with left upper abdominal pain and repeated vomiting  he had normal blood investigation. he had also mild cough and the Doctor found the unilateral wheezy chest on left side only and the chest x ray showed huge mass on left lung . The patient denies any chest infection ,TB, pneumonia or trauma but he had surgical history of colon interposition from 20 years back . The CT chest showed bowel dilated and obstruction which confirmed by upper GIT endoscopy. this case is rare case and infrequent presentation in ED . Regarding to evidence based practice, there is retrospective study at NCBI web site. Esophageal replacement with colon interposition in children:  M M Stone, E W Fonkalsrud, G H Mahour, J J Weitzman, and H Takiff. During a 21-year period, 39 colon interposition operations were performed on 37 children at the UCLA Medical Center and the Children's Hospital of Los Angeles. Only one case had distal stricture in colono esophageal anastomosis like our case and presented as late complication but in this case we report also obstruction with dilatation as result of the distal stricture. Emergency physician should be aware for un expected case presented  during  his work by routine exam and deferential diagnosis.  This case is infrequent case for intestinal obstruction in thoracic cavity may be present again in same or different situation.


Dr Islam ELROBAA (Al wakra, Qatar)
08:30 - 17:40 #9843 - Thoracic park.
Thoracic park.

Meet the killers of Thoracic park ; A review of the utility of point of care / Bed side ultrasound (including bed side Echo) in diagnosis of major life threatening conditions in patients presenting with cardio-respiratory symptoms ie arrest, Chest pain, Dyspnea.

Presentation involves multiple videos and case series as well as a review of ultrasound modalities that can be used (Lung, Echo, Vascular, etc)


Dr Pourya POURYAHYA (Melbourne, Australia)
08:30 - 17:40 #11598 - Thoracic ultrasound in differentiating dyspnoea in the emergency department.
Thoracic ultrasound in differentiating dyspnoea in the emergency department.

Background:

Acute dyspnoea is a common presentation to the emergency department (ED) and its differentiation can be challenging. Traditionally, chest x-ray (CXR) and clinical examination is used to aid provisional diagnosis. Ultrasound (US) is being used currently in the ED routinely and its application is expanding. Lichtenstein et al (2008) introduced a BLUE (Bedside Lung Ultrasound in Emergency) protocol for differentiating lung pathologies, however, that study was performed in ICU only.

Objective:

To evaluate the role of bedside thoracic ultrasound in differentiating causes of acute dyspnoea in the emergency department.

Method:

We designed a prospective observational study at the ED of an urban tertiary hospital. A convenience sample of adult patients presenting to the ED with acute dyspnoea were included from October 2016 to January 2017. A total of 56 patients were included for this pilot study.

A protocol was developed for differentiating causes of acute dyspnoea by using bedside US. It was performed as per protocol described in previous studies i.e., eight zones were scanned (four on each side). US were done by senior emergency physicians (EP) with level 2 emergency US experience. The thoracic US artifacts noted were A-lines, B-lines, lung sliding, lung point, alveolar consolidation and pleural effusion. Combined with focused echo and DVT scanning was used to diagnose possible pulmonary embolism. The results were recorded as either possible diagnosis of pulmonary oedema, pneumonia, pneumothorax, pleural effusion, pulmonary embolism, COPD/asthma or inconclusive (possible non-lung pathology).

The EP performing the US was blinded to history, examination and clinical impression of the attending EP. Findings of the US were recorded on a proforma and were kept blinded to the attending EP. All patients had a routine CXR and were treated accordingly by the attending EP and later by the admitting medical team who were also blinded to the US findings. An independent radiologist blinded to the US findings later reported all CXRs. Results of the US were retrospectively compared with CXR reports and the final diagnosis by the admitting medical team.

Results:

This study demonstrated the accuracy of thoracic US as follows: Pulmonary oedema (83.33% sensitivity, 95.24% specificity, 83.33% PPV and 95.24 NPV), pneumonia (50% sensitivity, 92.86% specificity, 66.67% PPV and 86.67% NPV), pneumothorax (100% sensitivity, 100% specificity, 100% PPV and 100% NPV), pleural effusion (85.71% sensitivity, 97.87% specificity, 85.71% PPV and 97.87% NPV), pulmonary embolism (50% sensitivity, 98% specificity, 66.67% PPV and 96.08% NPV) and COPD/asthma (50% sensitivity, 87.50% specificity, 83.33% PPV and 58.33% NPV).

Conclusion:

The results showed that bedside thoracic ultrasound in the ED can aid in the diagnosis in presentations with acute dyspnoea. We propose to extend this study in ED with larger sample size in order to validate our current results from this pilot study.


Muhammad Saif REHMAN (Abu Dhabi, United Arab Emirates), M Azam MAJEED, Asif NAVEED
08:30 - 17:40 #11957 - Thrombolyis in paediatric stroke - time for a change?
Thrombolyis in paediatric stroke - time for a change?

Abstract:

Stroke in children is a rare occurrence but with lasting and often life long morbidity.The vast majority of children with stroke were managed conservatively but recent guidelines do consider thrombolysis as the primary management strategy. We report a case of a right sided middle cerebral artery stroke in a 15year old female patient who successfully underwent thrombolysis. This case highlights the importance of early recognition and management of stroke in childhood.

Background:
The incidence of stroke in children can be up to 13 /100 000 children / year in the United Kingdom. Recognition of paediatric stroke can be particularly challenging as it can mimic several other conditions. The presenting symptoms and sings can be variable depending on the age.

Case:
A fifteen year old female patient presented to the Emergency Department with sudden onset of slurred speech, left sided facial palsy and weakness in her left arm.
She was previously healthy with no significant past medical history and no family history of note. She was on oral contraceptive pill for heavy periods.
She underwent an urgent CT brain which was consistent with right sided middle artery cerebral infarct. She was thrombolysed with Alteplase by the adult team within three hours of initial presentation.
She was subsequently transferred to a paediatric tertiary care unit for embolectomy but the thrombus had resolved on the MRI the same evening.
Her symptoms improved within 24hours with only some residual altered sensation on her dorsal hand and minimal reduction of power (4+/5) in her left wrist. She was discharged home on Aspirin 75mg once daily and with the advise to stop the oral contraceptive pill.
On follow up, her symptoms were fully resolved with no obvious other risk factor identified.

Conclusions
Stroke in childhood remains a neglected topic despite it being in the top ten causes of childhood death. The use of thrombolytic agent in children used to be an area of discussion with no RCT completed to support hyper acute thrombolysis.

Recent changes in paediatric stroke guideline advocate thrombolysis in paediatric population. Rivikin et al published a guideline which emphasises the importance of early recognition and prompt management of children with stroke in the Emergency Department.
The recommendation is to ensure neuroprotective measures and an urgent MRI brain to confirm the diagnosis. A treatment with tPA ( tissue plasminogen activator ) is recommended if there is evidence of vascular occlusion. Contraindications are time of symptom onset more than four and a half hours, age less than two years, intracranial haemorrhage etc.

The British Royal Colleague of Paediatrics are about to release the updated paediatric stroke guideline. The guideline reportedly recommends thrombolysis in children above the age of eight - an approach similar to Rivikin et al.

This case highlights a positive outcome of prompt adult approach in childhood. Early recognition of paediatric stroke is paramount to ensure timely management of patients. The delivery of such care requires appropriate infrastructure and awareness within the multidisciplinary team.


Anusha PONNAMPALAM (Nottingham, United Kingdom), Ahmed KAMAL, Manish PRASAD
08:30 - 17:40 #11618 - Time course of clinical and echocardiographic parameters during rTPA infusion in patients with pulmonary embolism at intermediate-high risk.
Time course of clinical and echocardiographic parameters during rTPA infusion in patients with pulmonary embolism at intermediate-high risk.

Background 

Patients with pulmonary embolism (PE) at high risk of adverse short-term event could benefit from thrombolytic therapy, however dose and mode of administration in PE patients varies among studies and data about efficacy in the first hours of treatment are lacking. 

Aim of the study 

This study aims to investigate in patients with intermediate-high risk PE the acute response during 2 hours i.v. infusion of 1 mg/kg rTPA in terms of changes in clinical and echocardiographic parameters. In particular we investigated whether these parameters significantly differ from baseline after 1 and 2 hours of 1 mg/kg rTPA infusion. 

Methods 

Consecutive adult patients with intermediate-high risk pulmonary embolism were considered for the study. Patients without contraindication to thrombolytic treatment and who gave written informed consent were included. Immediately before of the thrombolysis, and at 1, 2 and 24 hours, we measured systolic arterial pressure (SAP), heart rate (HR), oxygen saturation (SO2%), and right diastolic ventricle dimension (RVD), tricuspid annular plane systolic excursion (TAPSE) and right ventricle-right atrium (RA-RV) pressure gradient in apical four chamber view by echocardiography. Mean values were computed at each time and compared by general linear model for repeated measures (SPSS 19).   

Results 

From January 2016 to January 2017, eleven consecutive patients, 46% females, aged 71±17 years, were included. As shown in the table, mean values of all clinical and echocardiographic variables improved significantly at 24 hours (p<0.05 for all). However, each variables showed different time course. The only variable that significantly changed at 1 hour during rTPA infusion was the RA-RV gradient. The mean of this variable significantly decreased at 1 hour in comparison to baseline values, but did not further changed at 2 hour and 24 hours. SAP significantly increased at 2 hour and remained stable at 24 hours. TAPSE significantly improved at 2 hour and further increased at 24 hours in comparison to 1 hour values.   

Conclusion 

In PE patients at intermediate-high risk of adverse events, clinical and echocardiographic parameters changed with different patterns during rTPA infusion. RA-RV gradient improved already after 1 hour, earlier than the other echocardiographic parameters.  


Simone VANNI (Florence, Italy), Cosimo CAVIGLIOLI, Giulia SILVESTRI, Gabriele VIVIANI, Sofia ESPINOZA, Michele BAIONI, Roberto FEDERICO, Andrea PAVELLINI, Peiman NAZERIAN, Stefano GRIFONI
08:30 - 17:40 #11893 - Timing of Repeated head computerized tomography and its impact on the management of patients with moderate and severe traumatic brain injury (TBIS).
Timing of Repeated head computerized tomography and its impact on the management of patients with moderate and severe traumatic brain injury (TBIS).

The purpose of this prospective study over 100 patients who were admitted to surgical emergency unit was to define the indications, the timing and the frequency of repeated head computerized tomography (CT) scan in patients with moderate and severe traumatic brain injuries (TBIs) and to verify its impact on the management of those patients. we found that Performing an initial early CT brain within 2 hours interval from onset of trauma had a significance in comparison to 4 hours and 6 hours interval, none of the follow up CTs done upon improvement of GCS show any changes, more than half of patients who show new changes or progression of lesions in their follow up CT did it due to deteriorated GCS, the follow up CT done routinely showed progression or new changes in around 70 % of the patients and affected the management in 60% of patients, the majority of the follow up CT at which medical management was done (n=40) was arranged at 12 hours interval from the initial CT done (30%) followed by those arranged at 6 hours (25%) and at 4 hours (22%), while follow up CT at which surgical intervention was done (n=21) was those arranged at 4 hours interval from the initial CT done (28%) followed by those arranged at 12 hours (24%) and 24 hours (24%).


Sara BASHA (alexandria, Egypt)
08:30 - 17:40 #10552 - To determine the analgesic efficacy of intravenous paracetamol versus ketorolac and morphine for the treatment of acute renal colic.
To determine the analgesic efficacy of intravenous paracetamol versus ketorolac and morphine for the treatment of acute renal colic.

 

Abstract

Objective: To determine the analgesic efficacy of intravenous paracetamol versus ketorolac and morphine for the treatment of acute renal colic.

Methods : This study was a double blind randomized clinical trial that prospectively  conducted in emergency department (ED) during September 2012 to August 2013. Totally 150 subjects were randomly assigned in a 1:1:1 ratio to one of the following treatment groups: (1) A single dose of 1 g intravenous paracetamol (apotel) in 100 ml normal saline during 15 min; (2) A single dose of 10 mg intravenous morphine sulfate in 100 ml normal saline during 15 min; (3) A single dose of 30 mg intravenous ketorolac in 100 ml normal saline during 15 min. The severity of pain was measured based on 100 mm visual analogue scale from 0 mm to 100 mm equaling no pain to worst pain , and a verbal 4 points scales of mild, moderate, sever and very sever, respectively, just before intervention and 30 minutes after that.

Results: The pain intensity score was 36.13 ± 27.64 Visual analogue 30 min after intervention, pain score decreased significantly within 30 min compared to baseline pain intensity (P < 0.001). The most frequent adverse effect among the participants was dry mouth, which was more seen in morphine group.

Discussion: Similar efficacies were obtained for three medications, which were used in current study. However, the results suggested that comparing to morphine and ketorolac, paracetamol had lower complications


Ashkan TABIB ZADEH (Bandar Abbas, Islamic Republic of Iran), Reza YAZDANI, Morteza SAEEDI, Shojaeddin NAMAZI, Tahere AMIRSHEKARI
08:30 - 17:40 #11967 - To ED or not to ED in Greece? (Emergency Departments in Greece a necessity to take place).
To ED or not to ED in Greece? (Emergency Departments in Greece a necessity to take place).

To ED or not to ED in Greece?

(Emergency Departments in Greece a necessity to take place)

 

EDs is a practice all over the world, but something “new” in Greece

This presentation trying to prove the “benefit” that everybody (patient, EMS, Hospitals, State), all over Greece,  can gain from the establishment of the EDs & the Emergency Medicine as a specialty.

METHOD:

We create a simulation state program  to calculate the all the needs that are going to be asked in order to take place the establishment of the EDs & the Emergency Medicine for the NHS on duty in Attica

We analyzed the prehospital calls that EMS handle the last decay (2006-2015), through the parameters :

  1. time that an ambulance was engaged in a case &
  2. the distance that the ambulance “runs” on order to transport the patient in the hospital

The main idea was: we count the present situation & we calculate the same things in the simulation state

SIMULATION STATE: EDs in 6-8 Hospitals in Attica 24/7/365 & and the hospitals fully equipped to handle any case

PRESENT STATE 

ATTIKO HOSP

GKN PEIREUS HOSP

GKNA GENNIMATAS HOSP

KAT HOSP

THRIASIO HOSP

Voyla HOSP

% reduction of the distance of transport to hospital (shape)

% reduction of the time of transport to hospital (shape)

CONCLUSIONS

  1. 30-50% sooner   the patient to the hospital
  2. 30-50% more ambulances availability for the EMS
  3. 30-50% less cost of operation of EMS
  4. 25-30% reduction in hospital on-call costs
  5. reducing over 50% of daily workload for on duty hospitals

 

WHAT is the answer? To ED or not to ED in Greece?


Spyros PAPANIKOLAOU (ATHENS, Greece), Evaggelos PAPANIKOLAOU, Konstantina DIMITRIOU, Vasilis KEKERIS
08:30 - 17:40 #11663 - Toxin or tick: a challenging case of rash and fever.
Toxin or tick: a challenging case of rash and fever.

Introduction: Toxic shock syndrome (TSS) and rickettsial disease mimics each other because of their resemblance in clinical manifestations. It is sometimes difficult to distinguish TSS from rickettsial disease, especially in patients who are from areas where rickettsial disease is endemic.

Case: A 19-year-old menstruating woman presented with confusion and fever. She recently traveled to an endemic area of scrub typhus nine days prior. She developed fatigue and fever four and two days prior, respectively. On the day of presentation, she was brought to the emergency department because of decreased level of consciousness. On examination, her Glasgow coma scale was E4V4M6, body temperature was 39.8 Celsius degree, blood pressure was 106/40 mmHg, pulse rate was 136 per minute and respiratory rate was 36 per minute with an O2 saturation of 98% on ambient air. There were diffuse macular erythema and oral ulceration. Also, eschar-like lesion was detected on her left heel. Blood test showed leukocytosis, thrombocytopenia with abnormal coagulation profile, elevated levels of aminotransferases and creatinine. Chest and abdominal computed tomography without contrast only showed mild splenomegaly. Despite of aggressive fluid resuscitation for worsening hypotension, however, her blood pressure deteriorated. Vasopressor was initiated. Her respiratory condition also worsen, and ended up with endotracheal intubation. At this moment, she was suspected with rickettsial disease or TSS. Minocycline, clindamycin and tazobactam/piperacillin were empirically initiated to cover both of rickettsia and TSS. On day two, desquamation on her hands and chest were observed. Blood culture grew methicillin-sensitive staphylococcus aureus. Polymerase chain reactions of serum and tissue from eschar for rickettsia were reported as negative. Treatment was changed to cefazolin monotherapy.  On day five, vasopressors were discontinued based on improved blood pressure. On day six, she was extubated. She was discharged on day 19 with complete recovery after the completion of two-week treatment with antibiotics.

Discussion: This case illustrates the importance of making appropriate differential diagnosis in patients with shock, rash and fever in emergency department settings. In our case, travel history to the endemic area and eschar-like lesion biased the physician’s diagnostic thinking process. Positive blood culture for staphylococcus aureus and negative results of polymerase chain reactions for rickettsial disease elucidated the correct diagnosis. Timely investigations based on differential diagnosis should be critical. Treatments for both of TSS and rickettsial disease should be initiated for patients with rash and fever who were exposed in endemic area of rickettsial disease, because both of TSS and rickettsial disease can mimic each other and cause life-threatening conditions without appropriate initial therapy.


Makiko SHIINOKI (Mibu, Japan), Yukinori HARADA, Rie OGAWA, Koji WAKE, Taro SHIMIZU
08:30 - 17:40 #11439 - Tracheal intubation time with video laryngoscope versus direct laryngoscopy in a pre-hospital setting.
Tracheal intubation time with video laryngoscope versus direct laryngoscopy in a pre-hospital setting.

Introduction

Nowadays, video-laryngoscopes are widely used to perform tracheal intubation (TI), specifically when TI is considered as difficult. Operating conditions at pre-hospital level are very specific, and as for emergency departments, it could be considered that all intubations are difficult intubations.

The main identified added-value of video-laryngoscopes is to increase TI success but no evidence indicates that its use affects time required for intubation. However at pre-hospital level, time is an important aspect to take into account.  

The objective of our survey was to compare TI time with a video-laryngoscope versus direct laryngoscopy, when performed by emergency practitioners in difficult conditions

Methodology

29 physicians and nurse anesthetists were included. They each performed a series of 8 TI with an adult manikin with the same difficult airway management scenario (immobilized cervical spine). They all used an Eschmann tracheal tube introducer. They were randomly assigned to one of the following groups:

-        Group 1: 2 direct laryngoscopies (DL) followed by 2 McGrathâ video laryngoscope (McG), 2 DL and 2 McG

-        Group 2: 2 McG followed by 2 DL, 2 McG and 2 DL

They filled in a questionnaire with following variables: age, gender, number of performed TI per year, number of difficult TI per year, if they heard about McG before, if they already used one. TI times were divided into exposure time (expT), intubation time (intT) and verification time (verT). Each TI attempt was recorded using a chronometer. Quantitative measures were compared using the Wilcoxon test, and qualitative measures using the Fisher exact test.

Results

Mean age was 42 years old (ranging from 26 years old to 56), with 55 % of male. 55% of them performed more than 10 TI per year, with 14% of more than 5 difficult TI per year. 62% already heard about McG, and 35% already used it. There were no differences between the 2 groups for these variables.

All TI were successful at first exposure. TI times varied from 14.44 sec (ExpT), 29.50 sec (IntT) and 38.39 sec (VerT) for the 1st TI to 6.50 sec (ExpT), 16.39 sec (IntT) 23.36 sec (VerT) for the 4th DL with no difference between the 2 groups.

For McGrath video-laryngoscopy, times varied from 14.48 sec (ExpT), 36.28 sec (IntT) and 44.43 sec (ExpT) for the 1st TI to 7.91 sec (ExpT), 31.87 sec (IntT) and 40.34 sec (VerT) for the 4th TI with no difference between the 2 groups.

Conclusion

There was no difference among the 2 groups concerning TI time whether starting with DL or McG. The 4th TI was shorter than 1st TI with DL and McG.

In this survey, use of McGrath does not reduce TI time in a difficult airway management scenario with a manikin. These findings correspond to what was already published. A large part (1/3) of participants already used McGrath, whether in their daily practice or on a simulation manikin, and this might affect results. Evaluation of video-laryngoscopy in real life conditions will be the next step. 


Margot CASSUTO (Garches), Armelle SEVERIN, Anna OZGULER, Rosine BONNET, Michel BAER, Thomas LOEB
08:30 - 17:40 #10132 - TRACHEAL TRAUMATIC INJURIE.
TRACHEAL TRAUMATIC INJURIE.

Background: Tracheal traumatic injuries fulfil 0.8-2% of thoracic injuries. Tracheal ruptures are   a result of tracheal compression between the sternum and vertebra. Site of the rupture is on the membranous part of the trachea, 2.5 cm above carina.  Although not life treating condition rapid progression and detrimental outcome may be expected.

Case:  5-year-old boy weighted 25 kg, was admitted for observation to the ICU with stable vital parameters.  Discrete facial emphysema was present and radiographically confirmed pneumo-mediastinum. Rupture of the trachea was suspected due to fall and hit in the neck on the handles of a scooter.

   During admission, rapid emphysema enlargement and spread to the neck, thorax and abdomen occurred, respiration became insufficient, SpO2 fall to 89, HR rise to 156bpm.The child was intubated, sedated with propofol 400mg/50ml/4ml/h and VCV was initiated (Vt180ml, RR 20/min and FiO2 0.5%). Ausultatory pneumothorax was suspected on the left side and pediatric surgeon placed thoracic tube and collar incision.  Child was stabilized and antibiotics and corticosteroids were started.   Next day, bronchoscopy revealed tracheal lesion with present cartilage fragments that confirms tracheal fracture. After 14 days the child was discharged in good condition.

Discussion:  literature is poor with this type of cases but most of the literature agrees that rupture of the trachea mainly heals spontaneously. Intubation as precousion is not suggested because additional widening of the rupture may happen and pneumomediastinum may expand. The question remains when to intubate?

Conclusion:  when tracheal rupture is suspected breathing may become endangered so precautions must be taken so rapid and difficult intubation must be considered. The collaboration between the surgeon, ORL specialist and intensivist are part of the multidisciplinary approach to this cases. Time frame of the collaboration is essential for the patients outcome.


Marija JOVANOVSKI-SRCEVA (Skopje, North Macedonia), Maja MOJSOVA, Anita KOKAREVA
08:30 - 17:40 #10665 - Training nurses in evacuation categorisation in a teaching and non-teaching hospital, differences?
Training nurses in evacuation categorisation in a teaching and non-teaching hospital, differences?

Background: In hospital disaster preparedness, evacuation and more specific on patient categorisation is an essential competence that nurses are not trained in. The purpose of this study was to set up and to evaluate a categorisation exercise. An effective and feasible training method for all types of departments was searched for.

Methods: After an introduction, the nurses were divided in two groups. Both groups were asked to categorise all present patients and to place them in evacuation order. An exercise evaluation and a comparison between groups and baseline (made by researchers) was performed. An adjustment of the exercise was made depending on type of department: patient characteristics (mobility) and duration of intervention (developing types of exercises 1 to 4).

Results: For the university hospital 93 wards, functional units, operating rooms, ED and critical care units participated. Type 1 exercises: 34/54, type 2 exercises: 29/48 (9 wards missing data) and type 3 exercises: 21/27 (OR 12/14, CCU 8/12, ER). The exercise was highly appreciated. Feasibility was realistic: done within 40 minutes. In type 2 exercises, the equal scores were 82,11%. The comparison resulted in a high correlation (r2 > 0.86). For the non-teaching hospital 24 wards, functional units, operating room and recovery participated. Type 1 exercises: 12/12, type 2 exercises: 10/12 and type 3 exercises: 2/6. The exercise was also well appreciated and the feasibility was realistic: done within 45 to 60 minutes (introduction + exercise). In type 2 exercises, the equal scores were 70,70 %. The comparison resulted in a good correlation (r2 > 0,71).

Conclusions: A short and practical exercise on categorisation for evacuation was highly appreciated by the majority of all participating nurses and units of both hospitals. Although categorisation for evacuation is not a routine skill of nurses, surprisingly high correlation factors were observed. This indicates that the categorisation system is easy to apply and has practical implications. Categorisation has another purpose and executer than triage in incident situations. Namely, prioritising for evacuation is done by nurses. Within hospitals, nursing professionals represent a large group and the nature of their activities means that they will play an important executive role in the evacuation or relocation of a ward or hospital. After all, nursing professionals know the patients in their department best, especially in terms of general everyday activities, mobility and diagnosis. The assessment of patient's need for care during an evacuation or relocation, however, is an uncommon activity. But this is exactly why nursing professionals are best placedto undertake this action. Consequently, the hospital's nursing department has a responsibility in the execution and the preparation of contingency plans within hospitals. However, the use of a patient classification could not be applied as a regular element within the entire organisation.

 


Christel HENDRICKX (Anvers, Belgium), Marc SABBE
08:30 - 17:40 #10919 - Tramadol poisoning: a retrospective study from a french control poison center.
Tramadol poisoning: a retrospective study from a french control poison center.

Introduction

Tramadol is a very prescribe analgesic (step 2), mostly since the withdrawal of the Marketing Authorization Application of dextropropoxyphen in 2011. Tramadol is a central analgesic endowed with opioid effects, due to his fixation on the µ-opioid-receptor, and also with a serotonin-agonist effect due to the serotonin and noradrenalin reuptake inhibition. The aim of the present study was to identify the clinical signs of tramadol poisoning.

Méthods

We present here a monocentric and retrospective study conducted in a teaching hospital. All patients with Tramadol-poisoning reported in our Poison Control Center during 9 years (2007-2016) were included for statistical analysis.

Résults

A total of 127 cases have been collected. Mean age was 28.6 years old and 33% were 18 years old or less. The sex-ratio was 0.34. The presumated ingested dose was between 12.5mg and 12,000mg (mean: 792mg) per os. The extended-release form was used in 55% of cases. 66% of patients presented symptoms of intoxication. We reported involontary poisonning in 69% of cases (risk perception default, misuse, therapeutic errors) and the average of assumed ingested dose was 374mg. Clinically, the symptoms were vertigo (25%), nausea (20%), vomiting (20%) and somnolence (7%). Voluntary poisoning was reported in 31% of cases, including 2 cases of tramadol toxicomania. Reported ingested dose were between 125mg and 12,000mg (mean: 1,870mg) and  symptoms were: tachycardia (17%), myosis (15%), bradypnea (7%), coma (5%), seizure (5%), skin rash (5%). 7 patients had a Poisoning Severity Score (PSS) equal to 2 (middle gravity), 1 patient had a PSS=3. Finally, 59 patients were hospitalised (including 2 in the intensive care unit), 3 required naloxone reversal, 3 others received anti-epileptic medication, and for one of them mechanical ventilation was required. Poisoning with tramadol mono-intoxication remains uncommon: 127 cases on the 354 cases of poly-drug abuse associated tramadol to other toxics during the study period. Most severe poisonings were in a suicidal intent, in the context of misuse, overdose or addiction. Recent other studies reported other adverse effects such as hypoglycaemia, hyponatremia, SIADH, and acute pancreatitis. Those were not observed in our cohort.

Conclusion

Tramadol poisoning are symptomatic in two third of cases. Opiate toxidrome (myosis, bradypnea, coma) or serotoninergic toxicity (seizure, tachycardia) are mostly reported in cases of voluntary poisoning. In cases of tramadol intoxication, hypoglycaemia and hyponatremia should also be sought.


Romain DALLA-POZZA, Christine TOURNOUD, Eric BAYLE, Sarah UGÉ (Strasbourg), Mihaela MIHALCEA-DANCIU, Céline RENFER, Pierrick LE BORGNE, Pascal BILBAULT
08:30 - 17:40 #11331 - Tranexamic acid use in major haemorrhage at a non-trauma centre: how and when are we using it?
Tranexamic acid use in major haemorrhage at a non-trauma centre: how and when are we using it?

Introduction

Since the results of the CRASH-2 trial were published in 2010, tranexamic acid (TXA) use has become increasingly common in cases of significant haemorrhage secondary to trauma. However, utilisation of this antifibrinolytic agent in cases of major bleeding resulting from other pathologies is less well documented. The present study aimed to review how TXA is being used in cases of major haemorrhage treated at a non-trauma unit District General Hospital.

 

Methods

We performed a retrospective review of all cases of major haemorrhage from September 2015 to September 2016 at a single UK District General Hospital. Cases were identified by activation of a ‘Massive Bleed Standard Operating Procedure’, records of which are kept by the hospital’s Haematology Department. Data on presenting complaint, admission specialty, medications given in the emergency department, and procedures performed was collected and analysed.

 

Results

32 patients were identified and included in the analysis. The average age was 57 years (range 21 – 93). The reasons for activation of the massive bleed procedure included: aneurysmal bleeding (44%), obstetric bleeding (22%), gastrointestinal bleeding (16%), surgical bleeding (6%), polytrauma (3%), cardiac arrest (3%), spontaneous tension pneumothorax (3%), and severe anaemia (3%). TXA was used in 25% of cases (8/32), which included 5 patients with upper gastrointestinal bleeding (4 peptic ulcers, 1 angiodysplasia), 1 retroperitoneal haemorrhage following biopsy of a para-aortic mass, 1 post-partum haemorrhage, and 1 case of disseminated intravascular coagulopathy secondary to an amniotic fluid embolus. In 7 of these 8 cases, TXA was administered within 3 hours of the bleed and the dose given was 1g.

 

Conclusion

This review demonstrates that it was not commonplace for TXA to be used in cases of major haemorrhage at our institution. When it was used, it was most often for cases of gastrointestinal bleeding followed by obstetric complications, and was given at an appropriate time and dose. Further work would be needed to ascertain the role of TXA across this broad range of emergency presentations. 


Joe BARRETT-LEE (Dudley, United Kingdom), Thomas CLARE
08:30 - 17:40 #11563 - Transection of trachea caused by sharp object injury and airway manage with emergency tracheostomy.
Transection of trachea caused by sharp object injury and airway manage with emergency tracheostomy.

We present a rare case of transection of trachea followed by self harm with sharp obejct in the neck. A 38 years old female was brought to the department of emergency medicine of a tertiary care hospital after self harm with sharp wire on the anterior aspect of the neck. She was in respiratory distress, dysphonia, skin on the anterior part of the neck move in and out with respiration. The gap within the tracheal rings were felt beneath the skin. Prompt airway managment was performed by emergency physician and emergency tracheostomy was done. Then emergency neck expolartion was performed and anterior tracheal laceration was found. The trachea was transected which was managed surgically in the opeartion thater. Prompt and timely identification and management of airway problem is crucial for the survival in such cases.


Qazi ZIA ULLAH (MUSCAT, Oman), Mohammad Faisal KHILJI, Ali TARIQ, Sara AZIZ
08:30 - 17:40 #10509 - Transfusion index determination of the packed red blood cells in hospital emergency departments.
Transfusion index determination of the packed red blood cells in hospital emergency departments.

Introduction: Uncontrolled or no indication prescribing of blood products can cause increases cost, infections, transfusions complications, improper disposal, reduce blood bank reserves and inappropriate distribution of blood products. The goal of this study was determination of packed cells transfusion indicators in emergency department.

Patients and Methods:A cross-sectional study was done in patients admitted to the emergency department of Rasoul-e-Akram hospital, Tehran, Iran. Checklist was completed for each patient and packed cell infusion indicators were determined based on indication infusion. The infusion indication, complete and no complete infusion number were recorded.

Results: One hundred eighty-two patients were participated (125m/57f). The mean of age was 49.91 ± 20.98 years. Six hundred sixty-eight units of packed cells were requested for patients. The most indication for packed cell unit request was pre operation (53.8%). In 54.9%, cases 4 packed cell units were asked for the patient. One hundred twenty-nine two units were used (19.31%). Transfusion Rate (T %), C/T Ratio and transfusion index (TI) were 37.91%, 5.17% and 0.70, respectively.

Conclusion: Based on the results achieved red blood cell transfusion index in the emergency department (two cases of transfusion and transfusion index) were within acceptable limits, while the C / T Ratio value obtained with standard values far and the situation was undesirable.


Nafiseh ANSARINEJAD, Farshad FARDAD, Bahareh ABBASI, Tayeb RAMIM (Tehran, Islamic Republic of Iran)
08:30 - 17:40 #10884 - Transient glenohumeral instability following emergency physician performed ultrasound guided interscalene brachial plexus block for posterior dislocation management.
Transient glenohumeral instability following emergency physician performed ultrasound guided interscalene brachial plexus block for posterior dislocation management.

We describe, to our knowledge, the first case report of transient glenohumeral instability attributable to interscalene brachial plexus block. The patient had posterior glenohumeral instability for 2 hours after successful reduction of a traumatic acute posterior shoulder dislocation using emergency physician performed ultrasound guided interscalene brachial plexus block with 1% lidocaine. Motor effects of interscalene block may have led to reduced muscle tone, causing this transient instability. With point-of-care ultrasound guided interscalene brachial plexus blocks increasingly being used by emergency physicians for management of glenohumeral dislocations, awareness of this potential complication is important to avoid premature orthopedic consultation before the block has worn off. Moreover, if available, using a short acting agent such as 3-choloprocaine may avoid this complication. 


Dharmesh SHUKLA (Doha, Qatar)
08:30 - 17:40 #11044 - Transportation of Patients with Helicopter in Iceland – a Whole Nation Study on Outcome and Costs.
Transportation of Patients with Helicopter in Iceland – a Whole Nation Study on Outcome and Costs.

Introduction: Landspitali University Hospital (LSH) is the main hospital in Iceland and most critically ill and injured patients are transported to LSH. The emergency helicopter, run by the lcelandic Coast Guard (ICG), is an important part of the pre-hospital transport services and serves injured and ill people at sea and in remote areas. The purpose of this study was to review all flights of the emergency helicopter in lceland in 2001-2012.

Methods: The study was a qualitative, retrospective study. Information was gathered from patient files at LSH and flight data from the lCG. The following scales were used: Revised Trauma Score (RTS), Injury Severity Score (ISS), Trauma and Injury Severity Score (TRISS), NACA score and Modified Early Warning Score (MEWS).

Results: In 2001-2012 the emergency helicopter transported 704 patients, 466 injured and 223 sick. Males were 502 (71%) and females 202 (29%). Mean age was 40.2 years. The most common diagnosis of injured patients were injuries to the head (20%) or pelvis and lower extremity (20%). RTS was 7.429 ± 1.321 and ISS was 10.5 ± 13.8. Probability of survival (TRISS) was 94,0%. The mean NACA score was 3.4 ± 1.2 for injured patients and 3.8 ± 1.0 for sick patients. The mean MEWS score was 1.5 ± 2.4.Treatment was required in 84% of transports, cardiac resuscitation 17 times and intubation 37 times.

Conclusion: Many patients requiring emergency transport with helicopter are severely injured or sick and most get treatment on board the helicopter. The causes of transport are very diverse. Further research is needed to evaluate the importance of the helicopter for patient survival. 


Auður Elva VIGNISDÓTTIR (Reykjavík, Iceland), Sigrún Helga LUND, Viðar MAGNÚSSON, Auðunn KRISTINSSON, Brynjólfur MOGENSEN
08:30 - 17:40 #11841 - Trauma Care in Tarragona (Catalonia).
Trauma Care in Tarragona (Catalonia).

Background:

The Servei Catala de Salut categorizes hospitals according to their portfolio of services: trauma care center (CAT) 3 and 3e as high technology hospitals, CAT 2A and 2B with capacity to treat severe trauma, 2B being a reference for the traumatic patient in the health region. A system of coordination between prehospital and hospital care was established using PTT code (polytrauma code), divided into 4 priorities (P), P0: physiological affection, P1: anatomical affection, P2: according to injury mechanism, P3: special considerations. A computerized network record was created for all the centers: TraumCat

 

Methods:

We included prospectively 146 patients with a priority 0 and 1 between January 1 2014 and December 31 2016. We collected demographic, clinical and mortality characteristics in relation to the severity according to scores of adult and pediatric patients and compared them with those from the registry . Our trauma team PPT code is multidisciplinary and led by emergency medics

 

Results:

In 97.1% of cases, PTT code was activated, with prehospital warning in 81.1%. 56.4% were priority 0, 69.9% men, mean age 49 ± 20.7 years, 66% Spanish nationality and 94% had closed traumatisms. Traffic accidents accounted for 55.5%, with Thursday being the day with the highest incidence. 42.8% had intubated and 84.2% had a cervical collar, 86.9% had AIS greater than 3, a median of 4, 67.1% had an ISS greater than 15 median of 20, while That NISS was greater than 15 in 74%, median of 25. The overall mortality was of 21.2%, early mortality of 8.2% and late mortality of 13.6%. Adjusting for AIS, ISS and NISS, mortality does not present a significant difference compared to the Catalan registry, although the severity in our cases is higher than the mean of the registry

 

Discution:

The mortality of severe trauma in our environment is comparable to  the rest of Catalonia and to international registries


Gilmar PUGNET (miami platja, Spain), Doina SOLTOIANU, Jesus GALVEZ, Carmen BOQUE, Mª Montserrat OLONA, Jorge Alexis GUZMAN, Albert MORENO
08:30 - 17:40 #11048 - Trauma System Development in a maturing health care system – The United Arab Emirates experience.
Trauma System Development in a maturing health care system – The United Arab Emirates experience.

Trauma has been identified globally as one of the top ten public health priorities because of its medical and economic impact. The absence of a recognised multi-centre trauma registry in the Middle East led to the establishment of the Abu Dhabi Trauma network with all its components.

In our paper, we will aim to describe the need for establishment of the trauma system of which the trauma registry forms the backbone. We will also talk about the burden of disease due to the clear lack of trauma co-ordination in the Emirates. We will look at when the project started and what models were looked at as comparative equivalents as what the expected impact was to health care provision.

We will subsequently share our results to the audience and describe the limitations of the project. Finally, we will discuss in details the lessons learned and the future direction of the project so that other healthcare systems can benefit from our work.


Saleh FARES, Omar GHAZANFAR (Abu Dhabi, United Arab Emirates)
08:30 - 17:40 #10874 - Traumatic Diaphragmatic Rupture in child : Case report and review of literature.
Traumatic Diaphragmatic Rupture in child : Case report and review of literature.

Introduction :

The incidence of traumatic diaphragmatic rupture (TDR) is high in the trauma patients, and the thoraco abdominal viscera are frequently involved. Early diagnosis and surgical treatments are needed.

Case report: prehospital EMS (SMUR) transported to our resuscitation room a 10-year-old male child due to severe car crash injury (the driver mother was unfortunately dead on the scene). The boy was in front of the vehicle on passage seat with his seatbelt fasten. On his arrival in the resuscitation room, the boy was unstable with agitation, Glasgow Coma Scale 15, BP 10/5 HR 110/mn RR 40/mn SpO2 90%, Pain Scale 5/10. FAST examination was negative for free fluid, but the orientation of the spleen was felt by the Emergency physician to be unusual and the possibility of a splenic injury could not be ruled out. Chest x-ray was concerning for an acute, traumatic DR. A body CT scan confirmed the diaphragmatic rupture with herniation of a portion of the stomach into the chest. Insertion of a Naso Gastric Tube (NGT).  The young patient was transferred in a pediatric Trauma Center to the operating room where laparoscopic examination of the diaphragm revealed a 4.2 cm laceration in the diaphragm at the diaphragmatic adjacent to the stomach. He underwent an immediate surgery of the diaphragmatic rupture with no further complication.

Discussion:Traumatic diaphragm rupture (TDR) is a rare complication of trauma in pediatric age and may be easily missed by the severity of associated injuries so that delayed emergent presentation can occur with increased rate of morbidity and mortality.

Review of literature: blunt TDR accumulates as a result of the increased motor vehicle crashes with a mortality also accumulated because of high incidence of associated injuries such as splenic rupture, rib fractures due to the high energy dissipation required to rupture the diaphragm. TDR damage may be caused by a direct injury, an increased pressure gradient and avulsion forces transmitted by the internal viscera to the diaphragm. TDR following blunt trauma remains rare in children. Herniation of the stomach, small and large intestines, kidneys, and spleen may follow the rupture acutely or years after the original injury. The classic physical signs of diaphragmatic herniation include unilateral breath sounds, and bowel sounds over the lung fields, not consistently present. Many victims simply demonstrate respiratory distress but 90 -95% diaphragmatic ruptures have other significant injuries (lacerations of the spleen, liver, kidney,long bone fractures or head trauma). In acute phase, right-sided TDR in children often remains unrecognized in 10-50% of cases. The initial radiograph and CT scan may not be helpful. The injury is usually missed in approximately 50% of cases.. Chest X-ray is important methods for the detection of diaphragmatic rupture and herniation in 25% to 50% of cases. Laparotomy is the surgical approach to acute diaphragmatic rupture. An open thoracotomy, is a convenient approach for repair if there is no associated strangulation or perforation injury of bowel.

 

Conclusion: TDR, though uncommon, does occur and should remain a diagnostic possibility in children and require surgical correction. High index of suspicion is needed especially in children with blunt thoraco-abdominal trauma with pleural effusion and persistent serous effluent in the chest tube. Serial radiographs and repeat CT scan after intercostal drainage, helps in early diagnosis of this serious injury.


Eric REVUE (Paris), Alexandre HENNIART, Feti ZERHOUNI, Akim SADDAR, Anne TASSIN
08:30 - 17:40 #10951 - Traumatic Diaphragmatic Rupture in child : Case report and review of literature.
Traumatic Diaphragmatic Rupture in child : Case report and review of literature.

Introduction :Traumatic diaphragm rupture (TDR) is a rare complication of trauma in pediatrics and may be easily missed by the severity of injuries sand presentation can occur with increased rate of morbidity and mortality.

Case report: prehospital EMS transported to our ED a 10-yo male child due to severe car crash injury (the mother was unfortunately dead on the scene). The boy was in front of the vehicle on passage seat. On his arrival in the resuscitation room, the boy was unstable with agitation, Glasgow Coma Scale 15, BP 10/5 HR 110/mn RR 40/mn SpO2 90%, Pain Scale 8/10. FAST examination was negative for free fluid, but the possibility of a splenic injury could not be ruled out. A body CT scan confirmed the diaphragmatic rupture with herniation of a portion of the stomach into the chest.The young patient was transferred in a pediatric Trauma Center where laparoscopic examination of the diaphragm revealed a 4.2 cm laceration in the diaphragm at the diaphragmatic adjacent to the stomach. He underwent an immediate surgery of the diaphragmatic rupture with no further complication.

 Discussion: In literature, blunt TDR accumulates as a result of the increased motor vehicle crashes. TDR damage may be caused by a direct injury, an increased pressure gradient and avulsion forces transmitted by the internal viscera to the diaphragm. The mortality also accumulated because of high incidence of associated injuries such as splenic rupture, rib fractures due to the high-energy dissipation required to rupture the diaphragm.TDR following blunt trauma remains rare in children. Herniation of the stomach, small and large intestines, kidneys, and spleen may follow the rupture acutely or years after the original injury.The classic physical signs of diaphragmatic herniation include unilateral breath sounds, and bowel sounds over the lung fields, not consistently present.Many victims simply demonstrate respiratory distress but 90-95% TDR have other significant injuries (lacerations of the spleen, liver, kidney, long bone fractures or head trauma). In acute phase, right-sided TDR in children often remains unrecognized in 10-50% of cases. The initial radiograph and CT scan may not be helpful. The injury is usually missed in approximately 50% of cases.. Chest X-ray is important methods for the detection of diaphragmatic rupture and herniation in 25% to 50% of cases. Laparotomy is the surgical approach to acute diaphragmatic rupture. An open thoracotomy, is a convenient approach for repair if there is no associated strangulation or perforation injury of bowel.

Conclusion: TDR, though uncommon, does occur and should remain a diagnostic possibility in children and require surgical correction. High index of suspicion is needed especially in children with blunt thoraco-abdominal trauma with pleural effusion and persistent serous effluent in the chest tube. Serial radiographs and repeat CT scan after intercostal drainage, helps in early diagnosis of this serious injury.


Eric REVUE (Paris), Alexandre HENNIART, Amine ABDALLAH, Feti ZERHOUNI, Akim SADDAR, Anne TASSIN
08:30 - 17:40 #9978 - Traumatic pelvic hemorrhage resulted from disrupted obturator artery without pelvic fracture.
Traumatic pelvic hemorrhage resulted from disrupted obturator artery without pelvic fracture.

Background 

Pelvic or retroperitoneal hemorrhage are often associated with pelvic fracture thus Advanced Trauma Life Support (ATLS) guidelines recommend a routine use of pelvic x-ray in the primary survey. We experienced a case of pelvic hemorrage without pelvic fracture, which is very rare but fatal, thus report this case. 

 

Case presentation 

The patient is a 36 year-old man who was brought to our emergency department after his pelvis and right thigh were caught between ground and the fallen crane at the construction site. Presenting symptoms were pain on the right sigh to pelvis and the left shoulder.  

His blood pressure was 148/82mmHg, pulse 78/min, respiratory rate of 16/min with an O2 saturation of 100% on room air. We conducted clinical practice according to ATLS guidelines and started from primary survey. His airway was clear, and chest exams were normal. There was no external hemorrhage. Chest and pelvic x-rays were normal. Focused abdominal sonography in trauma was negative. There were no findings of disability. On secondary survey, he had bruise from the pubic bone to the buttocks. There was no abnormality when reading the pelvic x-ray in detail again. 

We then took contrast enhanced computed tomography which revealed extraperitoneal hemorrhage with extravasation on right caudal side of bladder. There were no evident organ damages and pelvic or femur fractures. Because active bleeding in pelvis was sustained, we performed urgent angiography and found extravasation in the peripheral branch of right obturator artery. We performed embolization to the disrupted brunch, and hemodynamics remained stable after surgery. He was discharged from the hospital on the day 15. 

 

Clinical significance 

Hemorrhage from vascular disruption of the pelvis without pelvic fracture is rare, and there are only a few case reports of pelvic hemorrhage associated with mild pelvic fracture such as stable type or acetabular fracture. However, when a shock of unknown cause due to trauma of the pelvis is recognized, hemorrhage from vascular disruption of the pelvis should be considered even without evident pelvic fracture. 


Shotaro KAWAMURA (Nagoya, Japan)
08:30 - 17:40 #10849 - Traumatic Pneumothorax-Chest X-ray vs e-FAST.
Traumatic Pneumothorax-Chest X-ray vs e-FAST.

A case report of a 39 year old male presented to San Giovanni Bosco Hospital (Torino, Italy), Accident and Emergency department, where I had been doing my EUSEM (European Society of Emergency Medicine) fellowship,patient after being involved an early morning road traffic collision.He had skidded from his motorbike at high speed and had sustained a right sided chest injury.Auscultation revealed decreased air entry on the right;his vital signs showed a decreased SpO2 of 90%, heart rate of 88 and a blood pressure of 120/80 mmHg.Routine blood tests determined a Haemoglobin 169 g/L,He was given intravenous morphine. His supine plain chest x-ray showed a minimal right sided pneumothorax and right sided rib fractures. Extended focused ultrasonography of the chest (e-FAST) showed a right sided pneumothorax. To confirm, he had a CT chest which confirmed the pneumothorax with multiple rib fractures that were displaced. Treatment involved high flow oxygen and insertion of a chest drain. 

Diagnosis of pneumothorax has typically been done by plain chest x-ray (CXR);however, this method (as demonstrated in this case) has been shown to have low sensitivity in detecting intrapleural air in trauma patients especially in the supine position [3, 4]. CT remains the gold standard for diagnosis of pneumothorax [12]; however, in the unstable trauma patient, getting a CT scan is not always possible to do safely, and it takes precious time. Fortunately, bedside ultrasound can provide real-time information in only seconds and is a logical evolution from FAST (focused assessment with sonography) scans that are already incorporated into trauma assessments for screening of blood around the heart or abdominal organs.  Several early trials [5,6,7] have established the diagnostic signs of pneumothorax on ultrasound and showed a strong superiority in favour over chest x-ray [8].The low-frequency, curvilinear probe (2-5 MHz) has been used by most authors for the detection of anterior pneumothoraces[12].Pneumothorax is typically confirmed by the presence of a stratosphere sign, abolished lung sliding or lung pulsing, the absence of B lines, and the presence of lung point.

Lung point is thought to be a 100% specific sign for pneumothorax; though the sensitivity is less satisfactory by the fact that lung-point cannot be found in every patient [7].

 

Supine plain chest x-rays are not a reliable test for pneumothorax, while ultrasonography, due to its extensive accessibility in emergency departments, is demonstrating a significant degree of diagnostic accuracy in the determination of pneumothorax [10]. Because lung ultrasound remains a relatively novel diagnostic approach, the technique to identify and quantify pneumothorax size is still under investigation. However, a recent systematic review [11] showed a sensitivity 0.87 (95% CI: 0.81-0.92) and specificity of 0.99 (95% CI: 0.98-0.99) for the e-FAST technique in identification of pneumothorax.


Dr Dalip KUMAR (Southend, United Kingdom), Matthew OSBORNE, Roberta PETRINO, Fiammetta PAGNOZZI, Mohammad WATFA, Michele COVELLA
08:30 - 17:40 #11682 - Treatment of burns in the ED in a secondary peripheral hospital.
Treatment of burns in the ED in a secondary peripheral hospital.

   Burns are a common cause of injury resulting in visits to the Emergency Department and potential risks of permanent damage or life threat . The purpose of this abstract is to record burn patients that came to the ED of the General Hospital in Chania in years 2014-2016 and how they were treated. From the records kept we have selected all the patients diagnosed with burns and followed their treatment. Each year about 180-200 patients visited the ED. 49% were female and 51% were male. The cause of burn was thermal in the 97% of them. 41% were first degree 52% were second degree and only 1% was third degree. The majority of those patients (93%) after taking care of  their wound were given antibiotics and instructions for observation on the outpatient department. 2% was admitted in a surgical clinic or an ICU and 0.5% was sent to a third level hospital.0,5% of them had an inhalant burn and needed intubation.  35% of the burns regarded the upper body and 22% about the lower body. 13,8% of the patients had burns in more than one body parts. About the extension of the burns 73.9% of the patients had burns on >10% of their body and only 2% had burns over 20% of their body. Most of the burns were caused in the summer (80%).

   There is no significant difference between men and women and most of the burns were in the upper body while the reason was mostly direct contact with flame or hot water. About their treatment the majority was taken care of the wound, given antitetanic serum and instructions for observation. A small number of patients with severe injury had to be sent in hospitals with burn units.

  In conclusion, burn lesions in our hospital have a relatively low yet constant incidence. Among these cases, most individuals, after the appliance of general wound care measures, can be observedas outpatients. Nevertheless, since burn wounds can potentially make part of more complex life threatening lesions, and the transfer to a  specialised burn center due to bad weather or instable patient’s condition  is not always feasible, our hospital should always remain in a high level of awareness as well as standard of care of burn victims which, as shown by our retrospective study, demonstrate a vast as well as impredictable degree of severity and complexity of problems to face and resolve.


Eleni TSAKIRAKI, Paraskevi KARONA (Chania, Greece), Georgios PETRAKIS, Athina ANAGNOU, Spyridon KAVROCHORIANOS, Emmanouil CHARITAKIS, Athanasios KOURAKOS, Konstantina PAPADOPOULOU, Ioannis KOKKINOS, Alexandros PAPADOMICHELAKIS, Miltiadis KASTANAKIS
08:30 - 17:40 #11164 - Treatment of Pediatric Patient in an Israeli Defense Forces (IDF) Field Hospital.
Treatment of Pediatric Patient in an Israeli Defense Forces (IDF) Field Hospital.

Study/Objective
The IDF Medical Corps has decades of experience in treating patients in disaster areas. The hospital was
recognized as the leader in field medicine and disaster relief, and became the first field hospital to ever
achieve a Type 3 rating according to a World Health Organization (WHO) scale.
Background
Worldwide, children are impacted by natural disasters particularly in Developing countries. Children in
disasters are often the most affected segment of the population but also the most overlooked. They are
more dependent on others for survival. The impacts of hunger following natural disasters can be
tremendous, causing lifelong damage to children’s development. Natural disasters can be particularly
traumatic for young children.
Methods
Operating a field hospital for a population affected by natural disaster is a complex mission. However,
pediatric care has its own unique, challenging characteristics. This realization led us to set up a separate
special pediatric division which included: Pediatric emergency department, Pediatric ward, Pediatric
intensive care unit, Neonatal intensive care unit, and an Ambulatory clinic. The pediatric division provides
for the primary and secondary care for pediatric patients including: Emergency medical conditions, Trauma,
Diagnosis and treatment of common acute & chronic diseases. The pediatric special team comprised of
pediatric emergency medicine specialists, pediatricians, neonatologists, pediatric surgeons, pediatric
orthopedic surgeons, pediatric anesthetists, nurses, medics, psychologists, and medical clowns.
Results
More then 1,000 pediatric patients were treated by the pediatric teams in previous delegations, hundred of
them required surgery. We have implemented unique methods to treat children, protocols for triage,
procedural sedation and analgesia, electronic medical record, etc.
Conclusion
We have a duty to learn and share our experience with colleagues worldwide. We hope that our experience
will help to promote further knowledge regarding disaster medical response for children, and enhance the
development of efficient algorithms and procedures for better preparedness.


Eran MASHIACH (GYVATAIM, Israel)
08:30 - 17:40 #10978 - Treatment with i.v. antiepileptic drugs in acute epileptic seizures.
Treatment with i.v. antiepileptic drugs in acute epileptic seizures.

Background: Four intravenous (i.v.) medications are available in Finland; fosphenytoin, valproate, levetiracetam and lacosamide. They are mainly used for ongoing or threatening status epilepticus (SE) but also in other clinical situations. The use of fosphenytoin/phenytoin has decreased globally due to side-effects and the increasing use of newer anti-epileptic drugs (AEDs). In the present study we aimed at i)assessing the indications  for the use of i.v. AEDs in emergency room (ER) settings, ii)studying the selection and efficacy of a given i.v. AED for prolonged seizures iii) evaluating of the duration  of door-to-treatment and from treatment to response.

Material and methods: We searched the medical records and databases to identify patients treated with i.v. AEDs in ER in year 2015. We recorded the treatment indication and AED. For the patients with the use of i.v. AED due to ongoing or imminent SE we collected the information on response. Positive response was based on EEG recording or with a clinical resolution of the symptoms. In addition, the door-to-treatment delay was recorded.

Results: A total of 78 patients received i.v. AED during their hospitalization period. 38 % of patients received i.v. AED for prevention of seizures during other ongoing acute condition (e.g. gastrointestinal sickness) or after recurrent seizures not considered as SE or due to post-ictal symptoms without registered seizure activity. 62 % of the patients received i.v. AED due to an ongoing epileptic event. I.v. levetiracetam was the most common first line i.v. AED. It was administrated in 78% of the cases, and in 8% (3 cases) combined with another AED. In 65 % there was a positive response to levetiracetam.  I.v. lacosamide, valproate and fosphenytoin were administrated in 19%, 4% and 2% of the cases, respectively. 67 % of the patients had a positive response to lacosamide.  The median time to the first line i.v. AED in the hospital was 43 minutes (range 10 -1145 min), and a positive response to treatment was documented after a median of 195 minutes (45 – 1225 min).

Conclusions: Levetiracetam and lacosamide were the most common first line i.v. AEDs for treatment of acute epileptic events at our institution. The use of valproate and fosphenytoin was rare. Impaired consciousness after cessation of motor seizure activity was a common phenomenon, which can make resolution of epileptic discharges difficult to detect. EEG is a necessary tool for evaluation of response to medication and it should be available all times. In this study nearly 1/3 of the patients didn’t show response to the first line i.v. AED. Because delays in commencing effective treatment for prolonged seizures decrease the possibilities for the termination of the event, reducing the time lag from onset of symptoms to i.v. AED treatment is important. For this goal, administering the i.v. AED on field should be considered. More data is definitely needed for reliable comparison of different i.v. AEDs.


Teemu PÖYTÄKANGAS, Satu-Liisa PAUNIAHO (Tampere, Finland), Sirpa RAINESALO, Jukka PELTOLA
08:30 - 17:40 #11031 - Trends in maxillofacial trauma in Chile: update after one year of follow-up in 3 high complexity Emergency Units (Fonis SA15l20196 project).
Trends in maxillofacial trauma in Chile: update after one year of follow-up in 3 high complexity Emergency Units (Fonis SA15l20196 project).

INTRODUCTION:
The maxillofacial trauma corresponds to one of the traumatic pathologies classified as the third cause of death worldwide and the fourth in our country. It has been described that as a health problem involves high costs in its intervention, with individual and productive losses, with high variability in its presentation according to sociodemographic factors and the level of development of the environment in which it occurs. Establishing an accurate diagnosis in its behavior at the population level constitutes the basis for effective measures in its prevention and control.

 

OBJECTIVE

The present study provides updated evidence describing the epidemiological behavior of maxillofacial trauma in Chile, based on the casuistry collected in 3 high complexity Emergency Units.

 

METHODS:

Observational, multicenter, individual-based study, grounded on the exploration of the clinical series of records for a full year of observation (May 2016 to April 2017). We included all adults with spontaneous consultation for maxillofacial trauma at the Adult Emergency Units of 3 hospitals in Chile, with an area of inclfuence of 3,000,000 population. Each center had 24 hours, 7 days a week and professional specialists for its intervention (maxillofacial surgeons). Information about the diagnosis, treatment and etiology of maxillofacial trauma was extracted, along with the sex, age and date of care of the patients. Summary measures analyses were made by establishing differences by Chi Square and non-paired Wilcoxon. Data were exploited in Microsoft Excel and Stata 14.0® statistical softwares. The project was approved by the Ethical Scientific Committees of each participating center and the Faculty of Dentistry in charge of the study.

 

RESULTS:
Seasonal occurrence was established, preferably on Thursday, Saturday and Sunday. The media age was around 40 years, with interpersonal violence as the most frequent cause of injury followed by falls and traffic road ones. Men predominated in all age groups except in those over 60 years. Most injuries corresponded to soft tissue traumas mainly by contusions, whereas lesions in the hard tissues predominated in the middle third, with differences by gender (p <0.05).

 

CONCLUSIONS:
The behavior of maxillofacial trauma was presented with a similar profile to that reported in high-level income countries, with discrete higher predominance of men at older ages. The main mechanism was interpersonal violence, although characteristics of the local culture typical of the population that inhabits these localities in Chile are evident.


Fabiola WERLINGER (Santiago, Chile), Valentina DUARTE, Marcelo VILLALÓN, Eugenio BÁEZ, Joaquín JARAMILLO, Raúl ACEVEDO, Leonardo AGUILAR, Rodrigo AGUILERA, Diego ALCOCER, Mario ARRIOLA, Oscar BADILLO, Rene BRIONES, Hugo COOPER, Marcela DEL RÍO, Cristian DÍAZ, Roberto GARCÍA, Rodrigo GOYA, Jaime HENRÍQUEZ, Mauricio HERRERA, Felipe MERCHAN, Marco NASI, Roberto OSBEN, Juan PASTRIÁN, Roberto REQUENA, Alejandro RIVERA, Santiago RIVIELLO, Juan ROJAS, Constanza VIDAL, Esteban ARROYO, Gastón RODRÍGUEZ, Juan CORTÉS
08:30 - 17:40 #11632 - Triage III - a cluster-randomized trial on the effect of introducing a prognostic biomarker in emergency medicine.
Triage III - a cluster-randomized trial on the effect of introducing a prognostic biomarker in emergency medicine.

Background: In emergency medicine the demand for safe and fast risk stratification is pivotal as more and more acute patients with increasing age and complex medical history are presenting at the Emergency Departments (EDs). In recent years, several biomarkers that carry prognostic information about the patient’s health have been found. These prognostic biomarkers have the potential to aid in the clinical assessment and risk stratification of acutely admitted patients and could be a valuable addition to the triage process. One of these prognostic biomarkers is soluble urokinase plasminogen activator receptor (suPAR). The protein is primarily expressed on immunologically active cells and reflects the overall state of immune activation of an individual. High suPAR is associated with the presence and severity of a broad range of acute and chronic conditions and is strongly associated with short term mortality in patients presenting at the ED. On the contrary, patients with low suPAR levels have a good prognosis and a low risk of short term death. These abilities potentially makes suPAR an ideal biomarker for risk stratification of unselected patients.
We conducted the TRIAGE III trial to assess if the availability of suPAR as a prognostic biomarker could improve risk stratification and assessment of acutely admitted patients, potentially leading to reduced mortality, a lower rate of complications, and more rapid patient flow in the ED. The main outcome was all-cause mortality .
Method: The trial was designed as an open prospective cross-over parallel-group cluster-randomized trial. The suPAR analysis was included in the routine blood work of all acutely admitted patients during the interventional periods. Six interventional periods of three weeks each were compared to similar control periods without suPAR measurement. The suPAR level was measured and reported to ED doctors within two hours of arrival. Prior to the study the clinical staff was informed of the prognostic capacities of suPAR.
Results: Patients were included from January 11th 2016 to June 6th 2016, and follow-up was until April 6th 2017. All outcomes will be assessed after this date. The trial included approximately 9,000 patients in both interventional- and control arm. We have recently received outcome data and are still in the progress of analyses. Results will be ready and be presented at the 2017 EuSEM Congress.
Conclusion: The TRIAGE III trial is to the best of our knowledge the largest prospective and first interventional trial on the effect of introducing a prognostic biomarker in emergency medicine . The trial investigates the concept: Available prognostic information can change the patient’s prognosis. This concept is central in triage and several other clinical situations. The TRIAGE III trial will have major impact on the use of prognostic biomarkers in the EDs and may also influence future clinical organizing and decision-making in emergency medicine.


Martin SCHULTZ (Copenhagen, Denmark), Line Jee Hartmann RASMUSSEN, Jesper EUGEN-OLSEN, Birgitte Nybo JENSEN, Lars KØBER, Theis LANGE, Lars Simon RASMUSSEN, Lisbet RAVN, Kasper Karmark IVERSEN
08:30 - 17:40 #11285 - Tricky triple A (Aortic Abdominal Aneuvrism).
Tricky triple A (Aortic Abdominal Aneuvrism).

     It is widely recognized that the elderly patient presenting with abdominal pain in the emergency  department is a challenge both in terms of investigations and differential diagnosis for  the emergency doctor.I bring to your attention a patient without abdominal complaints, but in which the final diagnosis was surprising; the pacient  V.G., aged 74 years, male, known with hypertension and prostatic adenoma, he followed treatment with antihypertensive, without known allergies. He complains of sore legs  since 2-3 days and he took for this reason six tablets of  painkiller, then, in the context of low  blood pressure values 80/60 mmHg at home, the patient falls and hits his right hemithorax on the radiator. At addmision, the patient was conscious, he accuses pain in both legs and in the right hemitorax; AV=81 beats/min, BP=84/59 mmHg, glucose=148 mg/dl, SpO2=94%, temperature=36.3 degrees Celsius. The pathologycal changes from clinical examination are:an obese hyperstenic patient with spontaneous and superficial pain at palpation in the rigt hemithorax but without traumatic mark at this level and without obvious abdominal trauma; pain and trophic disorders in legs bilaterally; urinary catheter for prostate adenoma, macroscopic hematuria and bilateral testicular bruising.The results of  the paraclinic exams are following:PA chest X-ray-the lungs expand to the chest wall without fluidopneumotorax, no ribs fractures;FAST-ultrasound posttraumatic normal appearance. Laboratory examinations showed the following: leukocytosis (21.000/ul), lymphopenia, neutrophilia, Hb=8.2 g/dL, Hct=24.3%, RBC=2.6x106/ul; glucose=155 mg/dl, urea=94.97 mg/dl, creatinine=2.41 mg/dL; total bilirubin=1.58; increased lactate=25; the urinalysis-500 leukocytes/uL, PCR=25.9 mg/L. The patient received treatment with crystalloid solutions, parenteral nutrition with Nephrotec and antibiotics.An urologyc consultation conducted in another unit, revealed no acute urologic pathology, and made recommendations for conducting urinalysis and a nephrologyst consultation. Coming back to the ER, the patient showed a suffering face, marked fatigue, mild dyspnea, TA=98/57 mmHg. The nephrologist suspected  an acute kidney injury by prerenal mechanism and he performed another abdominal ultradound which reveals  a fluid collections, located subdiafragmatic on the right side.

Given the noticeably worsened clinical condition of the patient, the appereance of abdominal pain, periumbilical echymosis, persistence of hypotension despite fluid resuscitation, we decided to perform an abdomio-pelvic native CT scan. Examination reveals a subrenal aneuvrysm of abdominal aorta of 73/80/78mm, ruptured in retroperitoneum.The cardiovascular surgery consultation decided to transfer the patient in the operating room.

The patient survived the laborious surgery, but with a unfavourable postoperative evolution, characterized by a marked hemodynamic instability and despite multidisciplinary team effort, he died next day.


Pavel FLORINA (Targu Mures, Romania), Mates OANA
08:30 - 17:40 #11425 - Tricuspid valve rupture: How did the diagnosis come?
Tricuspid valve rupture: How did the diagnosis come?

 
A 44-year-old patient who suffered a traffic accident with frontal collision of a vehicle against a tree, on arrival of the emergency team, the patient presented enolic fetor, low blood pressure and complete atrioventricular block. Sedation with orotraqueal intubation was started, transcutaneous pacemaker was placed and he was transferred to hospital emergencies. The emergency team performed the first hospital evaluation: complementary tests are performed with initial diagnosis of multiple trauma with thoracic trauma and cardiac involvement, complementary tests were performed: chest X-ray shows bilateral pulmonary contusion, Focused Assessment with sonography in Trauma ( FAST) was performed and injuries were discarded in first determination. Pacemaker was placed by left femoral access and a central venous catether was placed. The monitoring showed CVP of 27 cmH2O, after verification of the waveform, the doctor in charge of the case, seeked explanation. She did reevaluate the patient again and an echocardiography was performed. We saw an unsual image with a severe tricuspid regurgitation compatible with rupture of the valve, discarding effusion pericardial or other mechanical complication. Pacemaker cable end position was checked, transesophageal ultrasound was performed confirming the diagnosis of tricuspid valve rupture. The patient was admitted to the ICU and after stabilization , a tricuspid valve repair was performed. The same patient after surgery reparation showed a CVP of 7 cmH2O. The evolution was excellent and he was discharged home.
Conclusions
In polytraumatized patients it is important not only the medical examination, also the monitoring, the proper interpretation and the reevaluation of the patient taking into account the results obtained. The monitoring must be of quality, in addition to having the patient monitored in an invasive way (if circumstances allowes), we must know how to interpret the results and adapt to the new situation so changing especially in polytraumatized and sedated patients while waiting for their transfer to the operating room or the ICU.


María Palma BENÍTEZ MORENO, Marta JIMÉNEZ PARRAS (SPAIN, Spain), María Teresa VALLE GIL, Eduardo ROSELL VERGARA
08:30 - 17:40 #11162 - True Cause of Acute Neck Pain: Differential Diagnosis Between Acute Calcific Prevertebral Tendinitis and Retropharyngeal Abscess in Emergency Room.
True Cause of Acute Neck Pain: Differential Diagnosis Between Acute Calcific Prevertebral Tendinitis and Retropharyngeal Abscess in Emergency Room.

Background: The neck pain, sore-throat, dysphagia or odynophagia are frequent noted on acute calcific prevertebral tendinitis (ACPT) that is similar to retropharyngeal abscess(RA) which usually is combined with the higher rate of severe sepsis and air way obstruction. These two diseases also have resembled radiological findings. We always confound these diseases at emergency room. Here we present one series about the precise differential diagnosis between these diseases by the radiologic finding.

Methods: The patients are collected from Jan. 2010 to Feb 2017. There are 17 patients with thickening retropharyngeal space included in this review study. The diagnosis was verified by the review of medical records. We separate these patients into retropharyngeal abscess and acute calcific prevertebral tendinitis and try to find out the practical approach in neck computer tomography(CT), symptoms and signs and laboratory finding. The radiologist take in charge to review the radiological findings again. Fisher’s Exact Test is used for statistics analysis.   

Results: Of this study 4 cases are acute calcific prevertebral tendinitis and retropharyngeal abscess has 13 cases. There is significance in statistics about the CT finding of peripheral infiltration, peripheral enhancement and calcification at prevertebral space. Among the retropharyngeal abscess group peripheral infiltration and peripheral enhancement are 100% (13/13) and 0% (0/4) in acute calcific prevertebral tendinitis group. 7.7% (1/13) of retropharyngeal abscess  and 75% (3/4) of acute calcific prevertebral tendinitis patients have prevertebral calcification. The clinical symptoms and signs such as Severe Inflammatory Response Syndrome(SIRS), neck pain, dysphagia or odynophagia are not significant in statistics.

Discussion: The neck soft tissue image show increasing thickness of prevertebral space, which can give us the hint about the occurrence of retropharyngeal lesion. In our study contrasted neck CT should have more important part in the diagnosis of acute calcific prevertebral tendinitis and retropharyngeal abscess. The symptoms and signs could not be distinct in the early stage of two diseases. The needle puncture should be retained until the differential diagnosis of retropharyngeal lesion is still disturbed.


Chia-Hsi CHEN (Chiayi, Taiwan, Taiwan), Ying-Chou LU, Tak-Yee WONG, Jui-Fang HUANG, Su-Lan WU
08:30 - 17:40 #10901 - TrueCPR improves performance of chest compressions in simulated cardiac arrest performed by novice physicians.
TrueCPR improves performance of chest compressions in simulated cardiac arrest performed by novice physicians.

OBJECTIVE: The quality of external chest compressions (CC)is a key element for improvemend outcome in cardiopulmonary resuscitaion (CPR). However, as many studies indicated, performance of CPR is higly variable. We sought to evaluate if chest compressions are more effective with the use of a TrueCPR feedback device compared to standard CC.

METHODS: 43 novice physicians performed chest compressions on Resusci Anne manikin (Laerdal, Stavanger, Norway) with feedback device (TrueCPR group) and with manual CC without any device (control group). We simulated a two-minute cardiac resuscitation situation during ambulance transport using CPR training manikin. Ambulance was on the move with fast 10km/h. Every candidate performed the same scenario twice in ranndomized order, once with TrueCPR and once with manual CPR. They have 30-min brak between scearios. The primary outcome measure was the percentage of correct chest-compressions relative to total chest-compressions.

RESULTS: TrueCPR compared to manual chest-compressions were more frequently correct (90% vs 53%, p<.001). Median CC rate was significanltu higher in the control group (132 [interuqairtile range, IQR; 117-143] per min) compared with TrueCPR group (107 [IQR; 102-110] per min; p<.001). Correct CC depth was archived byy 41.5% of subjects without device vs. 83.1% with device (p<.001). Overall, 95.3% of all participntas thought the TrueCPR device was healpful and 97.7% would use it if avaiable.

CONCLUSIONS: TrueCPR real time feedback device improves certain aspects of CC quality performed by novice physiscians.


Szarpak LUKASZ (Warsaw, Poland), Smereka JACEK, Dabrowski MAREK
08:30 - 17:40 #10240 - Two cases of rare cystic brain lesions diagnosed following computer tomography for suspected intracranial haemorrhage.
Two cases of rare cystic brain lesions diagnosed following computer tomography for suspected intracranial haemorrhage.

With the increasing availability of computer tomography (CT) and magnetic resonance imaging (MRI) in Emergency Departments the number of incidentally diagnosed brain lesions has increased. An understanding of the pathogenesis, natural history and potential treatments of these lesions is vital to inform management. Discussed here are the cases of two men who presented to the Emergency Department of a large Dublin teaching hospital. First, a 35-year-old male who presented to the Emergency Department with reduced consciousness and periorbital bruising following collapse. CT head revealed a large cystic lesion in the right middle cranial fossa causing significant mass effect and herniation. Secondly, a 70-year-old male who presented to the emergency department having been found collapsed overnight. During admission, his consciousness deteriorated and, following CT head, a small colloid cyst obstructing the foramen of Munro causing acute hydrocephalus was diagnosed. These cases highlight the increasing prevalence of incidentally diagnosed cystic lesions and the need for an understanding of their natural history in order to inform and guide management. Their clinical presentations are discussed, their images displayed and their radiological findings reviewed. Also discussed are the pathogenesis, prognosis and management of these pathologies as well as the literature surrounding incidentally diagnosed brain lesions.


Robertson LEAR (Dublin, Ireland)
08:30 - 17:40 #10591 - Ultrasound scan as the radiological modality for adult male patient suspected as acute appendicitis how it affects patient quality of care? Qatar experience.
Ultrasound scan as the radiological modality for adult male patient suspected as acute appendicitis how it affects patient quality of care? Qatar experience.

Background:

Acute appendicitis(AA) is a frequent cause for adult male abdominal pain. It represents around 52 per 100,000 patients presenting to emergency department each year. Acute appendectomy is the most frequent emergency operation; however, the rates of unnecessary appendectomies are as high as 15%.

The standard tool of diagnosis is the pathological confirmation after removal of the inflamed appendix. With certain clinical points in history and examination, the need for radiological modalities could be omitted, although this opinion is a controversy.

Some studies reported GCUS sensitivity 44-100%, up to 91%. however, the length of stay, as an independent factor, is different from hospital to hospital and is not well studied.

Design:

Retrospective data analysis collected for all adult male patient (> 15 years old) presented to Hamad General Hospital emergency department (HGH-ED), Qatar with suspected acute appendicitis by the initial treating physician. Data collected from August to September 2015. The length of stay (LOS) is defined in our study as the time from patient ED registration till the final radiological reporting of his diagnosis.

Results:

132  patients were enrolled in our study, 94 patients had gone for GCUS as their initial scan of choice by their attending physician. The rest of the patients, 12 gone for CT abdomen with contrast directly and 26 patients had no scan at all. The average age of patients was 26.9 years.

94  patients (71.2%) had their first scan as GCUS, 64 was confirmed as AA. The rest 30 patients, 12 was confirmed to have other conditions.

18  of GCUS patients (19.1%), who had negative results, had to go for CT scan to confirm the diagnosis, 12 had a confirmed CT findings of AA.

12  cases had CT scan as initial and only scan, 8 had a radiological evidence of AA while the rest had different diagnoses. 26 patients had no scan at all, 14 cases had a clinical diagnosis of acute appendicitis, only 7 confirmed by the available pathological reports.

The average LOS was 11.8, 7.5, 4.4, 12.8 hours for the CT only, GCUS only, No image and US+CT groups respectively.

Conclusion:

GCUS is still the modality of choice in adult male patients suspected to have AA among the treating physicians.  The study revealed that GCUS has a shorter LOS comparing to other modalities. however, 19% of the patients may require further evaluation by CT scan which almost doubles their LOS time.

Study Limitations:

We were not able to obtain all the pathological reports of the study to confirm AA after radiological reports. The main reasons behind the variability of LOS among groups like CT only or NO scan are not addressed in our study and need further investigations.


Sherif ALKAHKY, Mohamed QOTB, Amr Mohammed ELMOHEEN, Ramy Mostafa ABDELKADER, Awny Abdelsalam ELHADAD, Abdalrahman Ahmed ABOSLEMA, Dr Ziad ALHARIRI (Doha- Qatar, Qatar)
08:30 - 17:40 #10922 - Undergraduate teaching in point of care ultrasound to medical students.
Undergraduate teaching in point of care ultrasound to medical students.

Purpose: Assessing and training ultrasound to undergraduate students of 3rd year medical assigned to Valme Hospital, University of Sevilla.

Materials & Methods: descriptive study developed in February, March and April of 2012 by 50 medical students from 3rd year who studied the subject of Medical Pathology. They were divided into groups of 8, and each group was taught a Theoretical and practical 4-hour workshop , the contents was the protocol Focused Assessment With Sonography in Trauma (FAST) for detecting abdominal free-flowing liquid. The workshop was led by two emergency physicians with extensive training and experience in clinical ultrasound. After the theoretical explanation of each block, students practiced the basic plans using their peers as models for over 3 hours. Upon completion, students had to complete a questionnaire and they were asked, using a Linkert 5-point scale (very good = 5, ... very bad = 1), to evaluate the agreement or  disagreement about their experience with the workshop. Their knowledge did not evaluate ultrasound.

Results: 100% of students (50) evaluated the workshop as very good and teachers, and 98% (49) assessed equally the teaching methodology. The students were excited about the practical part of the workshop, 98% of them (49) agreed that the usefulness and clinical applicability of ultrasound and its inclusion in medical training programs at undergraduate level would be essential. 100% of students suggested implementing more workshops as performed and in turn, that the workshop had been conducted had more hours and more educational content.

Conclusions: The vast majority of students were very satisfied with the workshop and, according to them, it should include training in clinical ultrasound in the formal curriculum of the Faculty of Medicine of Seville, since they believe will help them in their future practice as doctors, regardless of the specialty they will choose in the future.


Margarita ALGABA MONTES (Sevilla, Spain), Alberto Ángel OVIEDO GARCÍA, Francisco LUQUE SÁNCHEZ
08:30 - 17:40 #11484 - Undertriage in less urgent paediatric patients: risk factors and determinants for hospitalization.
Undertriage in less urgent paediatric patients: risk factors and determinants for hospitalization.

Background and aims:

Triage aims to quickly identify and prioritize critically ill patients among an increasing number of patients visiting the emergency department (ED). The Manchester Triage System(MTS) has shown to have moderate sensitivity and specificity in paediatric emengency care. Although patients triaged to less urgent categories are deemed to have negligible pathology , this is not always the case. This study aims to assess hospitalization rate for lower triaged paediatric patients and identify determinants for hospitalization and risk factors for undertriage.

Methods:

This is a retrospective analysis of paediatric patients (<16years old) who visited the ED of a tertiary university hospital in December 2015 and were categorized as non-urgent or standard according to the MTS used by physicians. Undertriage was assessed by comparing the urgency categories according to MTS with an independent reference for true urgency based on vital signs, possible life-threatening diseases and resource utilization.

Results:

A total of 1099 patients were triaged in less urgent categories of whom 88 (8%) were hospitalized. There were statistically significant higher hospitalization rates if the presenting problem was dyspnoea ( OR=4.43) or fever of unknown origin(OR=2.65). Patients 0-3 months old were also hospitalized more frequently (OR = 12.35). Those triaged by a consultant had lower hospitalisation rates (7.2%) than those triaged by junior doctors (8.2%), but this difference was insignificant. Undertriage occurred in 232 (21%) patients, of which 95% had one urgency level lower than the reference standard. There was a significantly higher risk of undertriage if the initial complaint was dyspnoea  (OR = 1.99) or limb problems (OR = 5.86) and if the patient was in age groups 0-3months (OR = 3.90) or 8-16years (OR = 2.67).

Discussion:

This study indicates a higher hospitalisation rate (8%) compared to earlier studies. Age < 1year old, dyspnoea and fever of unknown origin were known determinants for hospitalisation, and have been confirmed by this study. Dyspnoea is both a significant risk factor for undertriage as well as a determinant for hospitalization. While undertriage could be expected in younger age groups, the significant level for undertriage for older children was not expected. This result was probably related to a higher incidence of traumatic fractures.


Evert VERHOEVEN, Bugra DONMEZ (Brussels, Belgium), Gerlant VANBERLAER, Ives HUBLOUE
08:30 - 17:40 #11450 - Undertriage in less urgent paediatric patients: risk factors and determinants for hospitalization.
Undertriage in less urgent paediatric patients: risk factors and determinants for hospitalization.

Background and aims:

Triage aims to quickly identify and prioritize critically ill patients among an increasing number of patients visiting the emergency department (ED). The Manchester Triage System(MTS) has shown to have moderate sensitivity and specificity in paediatric emengency care. Although patients triaged to less urgent categories are deemed to have negligible pathology , this is not always the case. This study aims to assess hospitalization rate for lower triaged paediatric patients and identify determinants for hospitalization and risk factors for undertriage.

Methods:

This is a retrospective analysis of paediatric patients (<16years old) who visited the ED of a tertiary university hospital in December 2015 and were categorized as non-urgent or standard according to the MTS used by physicians. Undertriage was assessed by comparing the urgency categories according to MTS with an independent reference for true urgency based on vital signs, possible life-threatening diseases and resource utilization.

Results:

A total of 1099 patients were triaged in less urgent categories of whom 88 (8%) were hospitalized. There were statistically significant higher hospitalization rates if the presenting problem was dyspnoea ( OR=4.43) or fever of unknown origin(OR=2.65). Patients 0-3 months old were also hospitalized more frequently (OR = 12.35). Those triaged by a consultant had lower hospitalisation rates (7.2%) than those triaged by junior doctors (8.2%), but this difference was insignificant. Undertriage occurred in 232 (21%) patients, of which 95% had one urgency level lower than the reference standard. There was a significantly higher risk of undertriage if the initial complaint was dyspnoea  (OR = 1.99) or limb problems (OR = 5.86) and if the patient was in age groups 0-3months (OR = 3.90) or 8-16years (OR = 2.67).

Discussion:

This study indicates a higher hospitalisation rate compared to earlier studies. Age < 1year old, dyspnoea and fever of unknown origin were known determinants for hospitalisation, and have been confirmed by this study. Dyspnoea is both a significant risk factor for undertriage as well as a determinant for hospitalization. While undertriage could be expected in younger age groups, the significant level for undertriage for older children was not expected. This result was probably related to a higher incidence of traumatic fractures.


Evert VERHOEVEN (Etterbeek, Belgium), Bugra DONMEZ, Gerlant VANBERLAER, Ives HUBLOUE
08:30 - 17:40 #11156 - Undesired bridge.
Undesired bridge.

A 68-year-old male with a history of treated pulmonary tuberculosis, past smoker and moderate drinker, comes to the Emergency Room referring hemoptysis non-related with a cough since 4 hours ago, with no other present symptomatology.

On Physical examination, blood pressure is 130/70 mmHg, Heart rate 80 bpm, Respiratory rate 18 bpm and afebrile, with no relevant findings.

Analytics present no alteration, Hemoglobin 13.1 gr/dl, Biochemistry and coagulation within normal parameters.

He presents an episode of vigorous hemoptysis with hemodynamic instability, without oxygen desaturation and with a good level of consciousness. Intravenous volume repletion is started, vascular CT is requested and the ICU is alerted.

In the thoracic CT, radiologists describe a penetrating 2.2 cm diameter ulcer in the descending thoracic aorta that connects with the middle third of the esophagus. The esophagus is dilated and occupied by dense material, suggestive of coagulated blood.
Due to the hemodynamic instability of the patient, we decide to admit him on the ICU. Digestive endoscopy is performed, with high suspicion of fistulization of thoracic aorta to the esophagus as a result.
The patient is studied by the vascular surgeons, who decide to perform urgent surgery for endovascular treatment with endoprostheses.

Clinical diagnosis: aortic-esophageal fistula secondary to penetrating aortic ulcer.

The patient progresses adequately during admission without complications, except for bronchoaspiration pneumonia, being discharged nineteen days after arrival.

Conclusions:

The aortic penetrating ulcer is defined as the ulceration of an aortic atherosclerotic plaque that may accompany the formation of aneurysms and even rupture in up to 40% of the cases.
The most common location is the intrathoracic descending aorta. Usually, presents with chest pain and the diagnosis is made by angiography. Fistulization to the esophagus is rare and has a high mortality rate associated.
Treatment is surgical, based on the placement of a stent. Antibiotics should be prescribed given the high rate of mediastinitis associated. 


Isabel FERNÁNDEZ-MARÍN (Madrid, Spain), Víctor SÁNCHEZ ALEMANY, María CUADRADO FERNÁNDEZ, Ana SÁNCHEZ MORLA, Luis YUBERO SALGADO, Elena MARTÍNEZ CHAMORRO, Ana Belén CARLAVILLA MARTINEZ
08:30 - 17:40 #11019 - Unexpected prehospital breech delivery in the presence of emergency teams and telephone guidance by the regulating medical doctor. Retrospective observational study.
Unexpected prehospital breech delivery in the presence of emergency teams and telephone guidance by the regulating medical doctor. Retrospective observational study.

Introduction: The unexpected breech childbirth (UBC) of a newborn in non-hospital settings is a situation that can be faced by any pre-hospital emergency team. In case of non-progression of the fetus, the emergency team contacts the regulating medical doctor - on duty in a dispatch center - to be guided in the actions to perform urgently. The purpose of this study was to describe from our cohort of out-of-hospital births, actions as suggested by phone and outcome in the short term of newborns after telephone guidance by the regulating medical doctor.

 

Material and Methods: Retrospective observational study approved by an Ethics Committee.  Included were the UBC with telephone recording from our call dispatch center in which a guiding by telephone was directed by the regulating doctor. Five doctors analyzed the recordings independently from a standardized procedure. Variables collected: location of UBC, term, parity, delays "call alert - birth", "release of the head of the fetus," suggested actions, neonatal data (sex, weight, Apgar score, survival). Statistical analysis was uni- and bivariate.

 

Results: Over a period of 3 years, 15 (2%) UBC / 858 out-of-hospital births took place of which 9 breech deliveries /15 were guided by a regulating doctor. These 9 breech deliveries (100%) were primiparous in 7 cases/9 and occurred at home in 6 cases /9. The median term of pregnancy was 31 weeks gestation IQR [27-36]. One newborn had a non-viable term. The median time period of "call alert - birth" was 43 min IQR [34-50]; the release time for the head of the fetus was 2 min IQR [1-5]. The regulating doctor's suggestions concerned in all the cases the issue of the head and the orientation of the back of the fetus. Seven newborns / 9 had an Apgar score

 

Discussion: If the guidance by phone of the UBC seemed rare and its usefulness real, the UBD required medical resuscitation in half the cases. Low birth weight suspected before the term should alert the regulating doctor to the release problem of the head of the fetus. This study allowed for the development of an algorithm to help in guiding UBC in non-hospital settings for our regulating doctors. This algorithm is being evaluated


Isabelle KLEIN (PARIS), Sabine LEMOINE, Frédérique BRICHE, Colette MONOD-BROCA, Guillaume BURLATON, Marylin FRANCHIN, Michel BIGNAND, Daniel JOST, Jean Pierre TOURTIER
08:30 - 17:40 #11950 - Unusual Cervical wound in emergencies: A case report.
Unusual Cervical wound in emergencies: A case report.

Cervical penetrating wounds are as often "dry" than a cause of haemorrhages or lesions in adjacent areas. Except the fact that this type of lesion is spectacular, experience shows that lesional diagnosis is based on two facts, the state of the vital functions and the region of the neck concerned.

Z.K. 29 years old, a builder, a smoker, had no medical history, was taken to the emergency room by the SAMU (emergency medical service) following a fall of 03 meters at his place of work: the surface on which the patient had received Lined with iron bars No. 14 used in the building, stowed in the chain and erected vertically. The point of impact was facial. A bar of iron No. 14 pierced from side to side the cephalic and cervical region of the patient during his fall. The inlet port was the left cheek towards the Zygomatic bone, and as the outlet port the right inferior-lateral part of the neck (photos). For the pickup, fire-fighters were forced to saw the iron bar on the spot and could not remove it from the patient. This process took place under water to avoid burns caused by the heat of metal friction and with damping ways to avoid the shaking of the saw which could cause deep trauma.

At admission, the patient was conscious with a GS 15. He emitted sounds but was unable to articulate well. Hemodynamic and respiratory states were stable, blood pressure was 140/80 mmHg, π  95 cy/mn,  RR 16 cy / min and a sat O2 about 98% at AA. The iron bar that pierced his head and neck measured one meter Of length, and the position in back supine, did not allows any CT scan nor MRI examination. Pulmonary auscultation was free and symmetrical and the ECG was free of abnormalities. The rate of haemoglobin was stable; the first point of Hb was 13.8 g / dl and the second at 2 hour intervals was 13.2 g / dl. After a resuscitation and close monitoring in the 10-hour emergency room, the patient was taken directly to the operating room, under the supervision of a multidisciplinary team. Initially intubated and sedated in rapid induction, a tracheotomy was performed by an ORL physician with extubation and a cardiovascular surgeon removed the bar in the anterior posterior direction by controlling the bleeding. The patient was admitted secondarily in intensive care with a definitive lesional assessment, a fracture of the zygomatic bone.

Cervical wounds cause haemorrhage in once every three cases. Once in three, they are associated with craniofacial, thoracic or abdominal lesions. Their potential gravity increases, depending on whether their cause is a weapon, a handgun or low energy. Mortality, in civilian or military, oscillates between 3 and 6% and seems mainly due to vascular lesions.

The management of a cervical wound must be adapted to its potential severity. Serious, life-threatening injuries must be recognized and dealt with promptly. When the lesion appear to be less severe, risk situations and pitfalls must be recognized.


Zied GUERMAZI (Trévenans), Nour El Houda NOUIRA MZAHMA, Elmoez BEN OTHMANE, Sana LAHMAR, Farah RIAHI, Monia BOUSSEN, Mamoun BEN CHEIKH
08:30 - 17:40 #11695 - Unusual etiology of lumbar pain.
Unusual etiology of lumbar pain.

BACKGROUND

Lumbar pain such as renal colic is a frequent reason for consultation in emergency departement. Althought, lithiasis origin is the main cause, sometimes it can revele other pathology. We report the observation of a patient with acute abdominal pain which remaind unexplained by numerous explorations, causing a significant psychosocial repercussion.

 

CLINICAL OBSERVATION

A previously well man , 32 years of age presented to the emergency room for left lumbar pain evolving for two weeks with haematuria. The patient had consulted two physicians before and renal colic was the retained diagnosis. The patient was treated with non-steroidal anti-inflammatory drugs and paracetamol but without clinical improvement. The pain was insidious in onset and had an intensity of 08/10 on verbal analog scale .Physical examination on admission showed a conscious anxious patient, blood pressure of 120/70 mmhg, regular pulse rate of 118 min-1, respiratory rate up to  25 min-1 and temperature of 37.2°C.  The abdominal examination was normal. The abdominal ultrasound requested to search for renal calculs was normal. The abdominal CT scan showed The nutcracker syndrome, and the patient was transferred to the vascular surgery departement for further treatment.

 

CONCLUSION                                                                                                                     

Left renal syndrome (Nutcracker Syndrome) is an entity that can be encountered by physicians in a variety of disciplines.Main signs are hematuria, abdominal pain, pelvic varices and left varicocele. The natural history of the Nutcracker Syndrome remains poorly known: diagnostic and therapeutic modalities are therefore uncertain, but highly disabled patients can benefit from surgical or endovascular treatment.


Bassem CHATBRI (Tunis, Tunisia), Olfa DJEBBI, Yousra GUETARI, Rim HAMMAMI, Mounir HAGUI, Mehdi BEN LASSOUED, Khaled LAMINE
08:30 - 17:40 #11756 - Unusual Gastroenteritis.
Unusual Gastroenteritis.

Introduction :

Abdominal pain is a common reason for consultation in the emergency, but the etiological diagnosis is not always obvious.

Case presentation : 

A 26 –year –old woman with dystyroid and frequent hysterical crises, presented in our emergency department with abdominal pain and transit disorder.She was conscious ,polypneic , she had a normal blood pressure, normal glycemia . Symptomatic treatment of gastroenteritis has been initiated.Evolution: aggravation of transit disorders, diarrhea and vomiting, and consequently hydro electrolytic disorder. Initial laboratory results were within normal limits except for TP 74%. A toxic cause was then suspected, and the patient admitted the ingestion of 20 mg colchicines (suicide attempt).Laboratory results were perturbed: hyperleucocytosis and low TP (23%) the second day, rhabdomyolysis the third day .sixth day: thrombocytopenia without hemorrhagic syndrome. The patient was hospitalised in the intensive care unit and treated symptomatically in the following days with favourable outcome. 

Conclusion : 

Colchicine poisoning is a rare and severe intoxication. Its severity as well as the mortality rate is related to the ingested dose. Its treatment remains symptomatic. The initial clinical picture may be misleading outside of an evocative context.

 


Yousra GUETARI (Tunis, Tunisia), Dhekra HAMDI, Mounir HAGUI, Ghofrane BEN JRAD, Ines GUERBOUJ, Olfa DJEBBI, Khaled LAMINE
08:30 - 17:40 #11668 - Unusual localization of vitamin k antagonist over coagulation : About two case report.
Unusual localization of vitamin k antagonist over coagulation : About two case report.

Introduction :

Nowadays, anticoagulation’s therapy belongs to the most commonly used forms of pharmacotherapy in modern medicine. Overcaogulation of vitamin k antagonist treatment represent the most frequent cause of iatrogenic observed in the emergency department (ED) ,it was asymptomatic in 15 % to 30 % of case .  Some localization is rare when we haven’t a traumatic incident, and the diagnosis is difficult in emergency conditions.

Case report 1

We report the case of 47 years old men treated by vitamin k antagonist therapy for valvular replacement , the medical history didn’t objective a use of new medication . Besides there weren’t any traumatic incident in the past . The patient addressed to the emergency because of hematuria and lombar pain .physical examination showed a conscious patient with blood pressure of 140 /90 mm Hg and a regular pulse rate of 78 bpm .The abdominal examination showed a lombair tenderness, the urine test objective an hematuria . Prothrombin Time and international Normalised ratio (INR) levels were indosable. Other bilogical analysis did not noticed anemia .Andominal Computerized tomography revealed uretral hematoma without signs of neither compression nor extravasation and retroperitonel hematoma of left kidney. Conservative treatment was attempted and the patient was admitted to the emergency ward for observation, analgesia and specific antagonisation by vitamin K. the outcome was favorable after clinical correction of the homeostasis disorder.

Case report 2

An 86 years old man with a history of COPD, hypertension, diabetes and atrial fibrillation, presented to the emergency department with a sudden onset non traumatic paraplegia evolving for 24 hours associated to a lambar pain and a disturbances in bowel and blodder functions. Physical examination showed a conscious patient with blood pressure of 125 /74 mmHg and a regular pulse rate of 68 . Neurological examination revealed paraplegia with L2 sensory level. Biological tests showed an international Normalized ratio (INR) high levels (8.25) . The diagnosis of spinal cord compression was made and therefore a medullar MRI was performed. It revealed an enlarged posterior epidural hematoma from D9 to D12 responsible for spinal cord compression with D11-D12 cord signal abnormalities. The patient was admitted to the emergency ward for specific antagonisation by vitamin K and then transferred to the neurosurgery department for further treatment.

Conclusion

Over coagulation is the most frequent cause of iatrogenic events in the ED. Various bleeding complications are commonly associated with VKA use and consequences may be potentially fatal .Some localizations can preserve the prognostic of the patient.


Houda NASRI (CHARTRES), Bassem CHATBRI, Yosra GUETARI, Rim HAMAMI, Olfa DJEBBI, Dkhera HAMDI, Khaled LAMINE
08:30 - 17:40 #11243 - Upgrade ergonomic and quality care in the field: the medical mobile workbench.
Upgrade ergonomic and quality care in the field: the medical mobile workbench.

Introduction: There is a big difference between patient care in a hospital and in the field. Contrary to common practice taking place in a health facility, the emergency services have to adapt themselves to the given environmental conditions.

Context: prehospital teams have to bring suitable response and perform a number of technical procedures. Beyond the intensive-care ambulance, few alternatives exist and more often than not, materials lie on the ground in conditions ill-suited for correct practice.

Objectives: improving working conditions of the practitioners in the field (ergonomics, security, efficiency, quality, hygiene standards) to meet hospital health & safety rules.

Methodology: In a multicentric observation period, 6 intensive-care ambulances in 4 departments, has permitted to collect data on recurrent problems met in prehospital practices: infusion pole, lighting, weather protection, ergonomics, hygiene, waste management and safety rules. By taking into account not only these specific needs but also the recommendations issued by the CLIN committee (on nosocomial infections),a foldable ergonomic medical equipment that is easy to carry and ready to use in a few seconds could make a difference.

Results: Neither in scientific and industrial literature regarding medical devices, nor in domestic and international patents databases, did we find any evidence of a device meeting prehospital specifics needs. Preliminary 2D maps, then a 1:1 scale model size were made in order to validate this medical equipment towards EMS professionals. After the approval of this concept then the filing of a patent implementation, a fully operational prototype was completed then tested in the field for a full operating year. This feedback gave rise to the drafting of detailed specifications then to the building of a new prototype in 3 copies.

Prospects: these prototypes will be available on mobile units for a new period of comparative tests (intervention with or without the prototype). A satisfaction survey will then be completed in order to objectively measure the relevance of this medical equipment then eventually for a general use.


Samuel MERCIER, Hugues LEFORT, Olga MAURIN, Dr Abdo KHOURY (Besançon), Hélène MERCIER-JUTTIER, Christophe LAMACHE, Isabelle KLEIN, Daniel JOST, Jean-Pierre TOURTIER
08:30 - 17:40 #11170 - Upgrading the Treatment of Pediatric Trauma in Israel.
Upgrading the Treatment of Pediatric Trauma in Israel.

Study/Objective

Advertising expert committee recommendations for program improvement and upgrading of childcare trauma cases treated in Israeli hospitals in cases of moderate and severe injuries.


Background

Israel established the national trauma care system in the 1990's. It included a trauma unit at hospitals, the combination of paramedics and intensive care ambulances, the Magen David Adom (MDA EMS), established the National Trauma Registry, constructed and reorganized the emergency medicine departments, Advanced Trauma Life Support (ATLS) courses for doctors, technological improvements significantly in intensive care units, reducing response times and more. These and others led to a reduction in mortality of the severely wounded and those in critical condition. However, children’s injuries are still the leading cause of significant mortality and morbidity of children older than 1-year. Therefore, pediatric trauma is a serious problem of public health and a perceived social and economic burden. Moreover, it causes premature death, disabilities, impaired quality of life, and a burden on society and the victims' families.


Methods

In Israel, most trauma therapists who are mostly general surgeons have not had enough experience with children. On the other hand, pediatricians have knowledge and experience in child care but not in trauma. This causes the existing gaps in child care, in both a prehospital compound and a hospital.


Results

The committee's recommendations relate to the initial treatment of pediatric trauma, including stabilization and transfer phase and the first "golden hour." Recommendations for treatment in hospitals according to their levels include: National centers (Level 1 Trauma center), regional centers (Level 2 Trauma center), recommendations for trauma staffing (personnel), recommendations for upgrading equipment and infrastructure, training programs and refreshing knowledge and skills, and the development a PATLS course (Pediatric Advanced Trauma Life Support).


Conclusion

Writing a summary report, which was accepted by the Ministry of Health and by the National Committee for Trauma and Emergency Medicine, as a national work program for improving and upgrading childcare trauma cases.


Eran MASHIACH (GYVATAIM, Israel), Waisman YEHEZKEL
08:30 - 17:40 #11928 - Upper extremity deep vein trombosis.
Upper extremity deep vein trombosis.

Case report:

The case is presented of a 41 year-old women with no medical history of interest, who goes to emergency room due to edema in upper right limb.
Physical examination shows edema, erythema, and increased diameter of the limb with respect to the contralateral one.The ultrasound does not show thrombosis, but ectasia of the axillary vein and the brachial vein at the proximal level, with slow flow, and are collapsible. In view of the findings, a CT scan of the chest is requested where thrombus is observed in the right venous brachiocephalic trunk, without any signs of compression. The patient is admitted to Vascular Surgery, and fibrinolysis and posterior recanalization are performed. It presents a good evolution, with gradual decrease of edema and without pain. At discharge, anticoagulation is prescribed, and will be reviewed in 2 months.We believe that upper-extremity deep venous thrombosis is a rare condition that must be considered in patients with oedema of the upper limbs. The key to a prompt diagnosis is to know the risk factors. Ultrasound is the standard approach.

Discussion: 

Upper-extremity deep venous thrombosis is less common than lower-extremity deep venous thrombosis. According to the literature, approximately 4–10% of all cases of venous thrombosis may involve the subclavian, axillary or brachial veins. However, upper-extremity deep venous thrombosis is associated with similar adverse consequences, so it is a rare condition that must be considered in patients with edema of the upper limbs.
Upper extremities deep venous thrombosis is classified as primary, approximately one-third of cases, which refers either to effort thrombosis or idiopathic, or secondary, due to the presence of overt predisposing causes. The onset of is usually characterized by arm swelling and pain, but may also be completely asymptomatic.
The imaging technique of choice for diagnosis is Doppler ultrasonography, but intravenous contrast CT allows a better assessment of the extent and the presence of associated locoregional lesions.
This entity has major clinical consequences including pulmonary embolism, recurrences, post-thrombotic syndrome, and death. Unfractionated or low molecular weight heparin, followed by an oral anticoagulant are the most common treatments, with strategy of management similar to that of deep vein thrombosis of the leg. Thrombolysis/thrombectomy and surgical decompression are often successful, but less frequently used. Randomized controlled trials are warranted to clarify the optimal management of upper extremity deep vein trombosis, and to identify patients at the highest risk of recurrence who might benefit from long-term anticoagulation.

 


Maria Del Carmen RODRIGUEZ CASIMIRO, Carmen A YAGO CALDERON (Malaga, Spain), Enrique CARO VAZQUEZ, Diana DIZ GONZALEZ, Miguel MARTINEZ IBANEZ, Juan A RIVERO GUERRERO, Valentina MORELL JIMENEZ
08:30 - 17:40 #10933 - Use of Hyperbaric Oxygen Therapy in Critically ill Patients.
Use of Hyperbaric Oxygen Therapy in Critically ill Patients.

Hyperbaric Medicine is a medical area that studies the physiological adaptations, recreational and professional activities in hyperbaric environments, as well as the prophylaxis and treatment of diseases due to unscheduled decompression.

Hyperbaric Oxygen Therapy (HBOT) is the scientific use of pure oxygen (100%) under high pressures (2 to 3 ATM) for the treatment of diseases. This increase in pressure and the use of pure oxygen results in a very significant increase in arterial oxygen pressure (about 2000mmHg) and tissue (400mmHg). It is a non-invasive therapy used in the treatment of decompression sickness of divers, depth workers and certain pathologies.

HBOT reverses tissue and cellular hypoxia, restores organic defense and increases phagocytic capacity over some bacteria (bactericidal and bacteriostatic effect). With the reversal of hypoxia, the stimulus for the formation of the essential collagen matrix for angiogenesis and healing occurs.

HBOT indications include critical patients, including: acute carbon monoxide poisoning, decompression sickness, gas gangrene, necrotizing fasciitis, and crush injury

We will describe the evolution of 3 critical patients from different pathologies who underwent HBOT, were treated at the Hyperbaric Medicine Center of Ribeirão Preto.

Case 1 - Abdominal Wall Fasciitis - male, 49 years old, postoperative colectomy (colostomy) right due to a Right Cervical Cancer. It evolved with septicemia, abdominal peritonitis and fasciitis in the abdominal wall. It was treated with: peritonostomy, antibiotic therapy and HBOT. After 40 sessions of HBOT there was a significant improvement of the condition, with closure of the abdominal wall and hospital discharge.

Case 2 - Fournier Syndrome - man, 7 months old. He started the picture with fever and red spot inter gluteus, which rapidly evolved to area with necrosis and septic shock. He underwent surgical debridement and started treatment with HBOT. After 30 sessions of HBOT presented excellent evolution, being referred to the plastic surgery service.

Case 3 - Hemorrhagic Cystitis - woman, 44 years old, cervical cancer. She underwent surgery, chemotherapy and brachytherapy. After 4 months of the end with brachytherapy presented cystitis hemorrhagic. It was treated with HBOT (10 sessions), with total regression of the clinic.

Conclusion: The evolution of patients treated with Hyperbaric Oxygen Therapy was significant. Hyperbaric Oxygen Therapy is indicated as adjuvant treatment and the expected effects are: direct antibacterial effect on anaerobes, reduction of tissue endotoxin activity due to high oxygen concentration, reduction of edema due to vasoconstriction and stimulation of neovascularization.


Rosemary DANIEL (ribeirão preto, Brazil), Santos LUIS, Matheus FERREIRA, Lelio PINTO, Melissa CESARIO, Rodrigo BRIGATO, Jussara AQUINO, Omar FERES, Deborah FERREIRA
08:30 - 17:40 #10947 - Use of low-dose of direct action anticoagulants (NOAC) in non-valvular atrial fibrillation (NVAF) and flutter (FL) patients at the emergency departments in Aragon (Spain).
Use of low-dose of direct action anticoagulants (NOAC) in non-valvular atrial fibrillation (NVAF) and flutter (FL) patients at the emergency departments in Aragon (Spain).

Objectives:

New oral anticoagulants’ efficacy has been demonstrated by multiple trials, in most of them priority is given to security of the drug rather than to its efficacy. All NOAC have a low-dose formulation in order to ensure the security aforementioned. Our aim is to analyse the low-dose NOAC percentage used in NVAF and FL patients, prescribed for the first time at the emergency departments of Aragon.

 

Material or patients and method:

SArA IV is an observational, descriptive, retrospective study included older than 14 years old patients who underwent AF or FL at the emergency department of the SALUD hospitals, during the period between July, 1 and December, 31 of the years 2012, 2013, 2014 and 2015. Data were obtained from the patient’s computerized medical history and were processed in ACCESS; SPSSv15.0 (chi-squared test) was used for descriptive analysis.

 

Results:

From the study population of 8900 patients, 5.959 (66%) of them initiated anticoagulation therapy at the emergency departments; NOAC were prescribed to 1.227 (20.6%). In the NOAC group, overall, low-dose NOAC formulation were prescribed to 344 patients (28%): Dabigatran was prescribed to 406 patients, 137 (33.7%) with low-dose of 110 mg; Rivaroxaban was prescribed to 564 patients, 152 (27%) with low-dose of 15 mg; and Apixaban to 257 patients, 55 (21.5%) with low-dose of 2.5 mg.

 

Conclusions:

Low – dose NOAC formulations were used in 28% of the patients who initiated anticoagulation with NOAC, similar figures to pivotal studies and below data of real life studies.

Dabigatran 110 mg is the most used low-dose NOAC formulation representing 33.7% of its prescriptions (unique NOAC whose low-dose formulation was studied in a single – arm trial independent of de pivotal study and has anticoagulation indication with efficacy tested).


Victoria ORTIZ BESCÓS, Isabel PÉREZ PAÑART, Román ROYO HERNÁNDEZ, Marta DEL PUEYO PARRA, María De La Peña LÓPEZ GALINDO (Zaragoza, Spain), Joaquín GÓMEZ BITRIÁN, Patricia ALBA ESTEBAN
08:30 - 17:40 #11836 - Use of Mindfulness for Resiliency to Disaster Response and for Self-Care in Deployment.
Use of Mindfulness for Resiliency to Disaster Response and for Self-Care in Deployment.

Study/Objective:

To review the literature of Mindfulness Based Stress Reduction (MBSR) interventions for disaster responders, as a component of pre-deployment resilience, and self-care during deployment, to help minimize risk of acute stress response, depression and post-traumatic stress disorder (PTSD)

Background:

‘Mindfulness’ is derived from Buddhist meditation practice. Mindfulness programs have been shown to improve clinicians’ perceived stress, anxiety and performance in medical practice. Mindfulness, specifically MBSR, an evidence based approach that uses mindfulness meditation, is demonstrated to be successful in treatment of PTSD in populations such as veterans.  Disaster responders, like the military, are a population potentially vulnerable to adverse psychological effects given the nature of disaster response: unexpected, sudden, devastating events. A quarter to one third of disaster responders report symptoms of anxiety, depression and PTSD, secondary to exposure to stressors of disaster response. Currently few evidence based resiliency strategies, for disaster responders, prior to deployment and during deployment, exist. Teaching MBSR practice to disaster responders, prior to deployment, and continuing meditation practice during deployment, has potential to decrease the adverse psychological consequences of disaster response.

Methods:

The authors performed a systematic review of peer reviewed literature indexed in PubMed, psycINFO, Web of Science and Google Scholar. Abstracts were limited to human studies, in English, and search terms MBSR, disaster responders, pre- deployment, acute stress response, depression and PTSD. Articles were also found by searching citations of retrieved articles.

Inclusion criteria:  articles dating after 1990’s, English text and good research design. 

Exclusion criteria:  poor research methodology, non-English text and poor research design.  A total of 600 articles were found and 55 were use based on inclusion criteria.

Results:

Literature exists showing that pre-deployment mindfulness training in military personnel improves perceived stress and stress response, and likely improved resilience to trauma of deployment.  No similar research was found for disaster responders.  Little has been researched about the utility of mindfulness practice during deployment, to improve adverse psychological consequences of disaster response.  A limitation encountered was that, few high quality Randomized Clinical Trials (RCTs) and studies exist, as conceptual mindfulness has limitations of its study within rigorous, scientific research methodology.

Conclusion:

More research is needed to explore the potential of mindfulness training on disaster medicine clinicians, prior to deployment and for self-care practice during deployment.  It is a tool with potential to mitigate detrimental psychological consequences of disaster response work. 


Sukhshant ATTI (Boston, MA, USA), Reem ALFALASI, Selwyn MAHON, Amalia VOSKANYAN, Ritu SARIN, Michael MOLLOY, Gregory CIOTTONE
08:30 - 17:40 #11588 - Use of noninvasive mechanical ventilation in patient with cardiogenic pulmonary edema and acute coronary syndrome – Case report - emergency departments in Croatia.
Use of noninvasive mechanical ventilation in patient with cardiogenic pulmonary edema and acute coronary syndrome – Case report - emergency departments in Croatia.

Introduction: Emergency medicine physicians evaluate and treat patients with acute respiratory insufficiency daily. Nowadays, the use of noninvasive ventilation has also spread in emergency departments and has become an indispensable in treating patients with acute respiratory insufficiency. Two main indications for noninvasive ventilation are cardiogenic pulmonary edema and exacerbation of chronic obstructive pulmonary disease. The success of the therapy depends on early onset with strict monitoring. Noninvasive ventilation is the form of mechanical support with positive pressure breathing through the upper respiratory tract using mask or other devices. The advantages are reduction of the need for invasive mechanical ventilation, shortening of hospitalization, lower mortality and significantly lower complication rates compared to invasive mechanical ventilation treatment as first choice therapy. 

The aim of this study was to describe advantage of early application of noninvasive mechanical ventilation in 88- year old patient with cardiogenic pulmonary edema and acute coronary sindrome who was admitted at emergency department. Although, noninvasive mechanical ventlation is not indicated in patient with acute coronary event, application of noninvasive ventilation at emergency department resulted in clinical improvement and favorable outcome of the patient. 

Conclusion: In this study, we have shown 88- year old patient with cardiogenic pulmonary edema and acute coronary sindrome in which early noninvasive ventilation has led to clinical improvement, shortering of the intensive care and the need for endotraheal intubation was avoided. Despite the contraindications for use of noninvasive ventilation in patients with acute coronary syndrome, the patient we presented has shown results in its improvement and stabilization by using noninvasive mechanical ventilation. The question is whether acute coronary syndrome accompanied by cardiogenic pulmonary edema is indeed a contraindication to the noninvasive ventilation, which is yet to be determined by further studies. Despite the wide application of noninvasive ventilation in emergency medicine centers around the world, the lack of valid guidelines for use is a basic issue. In our emergency department we started using noninvasive ventilation two years ago. Noninvasive ventilation is mostly used in intensive care units, and for the long time being, the emergency department personnel is not adequately educated in noninvasive ventilation. It provides numerous advantages over conventional treatment methods and invasive ventilation, so noninvansive mechanical ventilation should be found in the standard equipment od each hospital for treating patients with acute respiratory insufficiency. Noninvasive ventilation as a treatment for acute respiratory insufficiency is one of the greatest technical achievements of respiratory medicine in the last 20 years and should be routinely applied in emergency medicine centers. 


Klara POLDAN SKORUP (RIJEKA, Croatia), Dijana DUMIC, Ivana DATKOVIC, Vlatka SOTOSEK TOKMADZIC, Martina PAVLETIC PERSIC
08:30 - 17:40 #11142 - Use of novel software-based patient transfer system in the emergency department setting.
Use of novel software-based patient transfer system in the emergency department setting.

Crowding and EXIT block are common problems at emergency departments (EDs) worldwide. Patients that are ready for transportation either to a ward at the same hospital or at another institution often wait for a long time to be transported. This binds ED resources as these patients often require nursing care. Again, prolonged length of stay in ED causes increase in mortality and length of hospital stay.

 Prior to transportation, the nurses need to contact the ward where the responding nurse may be busy in patient care. This can prolong the waiting time even further. Due to the lack of compatibility of electronic medical records, information about destination’s occupancy is usually not known, and often several phone calls are needed to inquire occupancy. No reliable statistical data is available on the transfer process.

 In order to ease this communication problem, a company founded by IT-enthusiastic doctors has developed a software for patient transfer process. This program (Uoma) is used by both the sender (e.g. ED) and receiver (e.g. hospital ward). The receiving party maintains up to date information about their ward’s occupancy. Hence, the referring unit is aware of the real-time availability of beds. The sending party inserts data on patient’s current status (e.g. diagnosis, mobility, need for isolation, cognition, sender’s contact information) into a structured form, which acts as a checklist, thus reducing risk of human error and improving patient safety. After sending the data, the receiver gets instant notification from the software. The receiver can accept the patient to their ward, ask for additional time e.g. for organizing free beds or decline the transfer. In the latter case, other predefined wards will also receive a notification from the system and can accept the patient to their ward. Again, there is an in-patient chat for communication between organizations, which enables asynchronous communication instead of the system based on phone calls. This system is built on SaaS-principle (software-as-a-service) to make implementation of the software as easy as possible.

The first pilot in public healthcare started at the end of 2016 in Tampere University Hospital’s emergency department, Tampere Hatanpää Hospital and 4 surrounding health centers. Initial results are promising: the staff has adopted the system quickly, phone calls have decreased significantly, in-patient chat has been successful in providing extra info and checklist has unified the status reporting. There were occasional delays in answering to the transfer requests, most likely caused by novelty of the system. The phased deployment of software caused the need for using two simultaneous methods (old call-based and new software-based) which caused some negative feedback. However, the overall feedback has been very positive. The software has enabled remodeling the patient transfer process towards more efficient, safer and cost-effective way.


Taavi SAVIAUK, Anssi SEPPO, Miika PIHLAJA, Niku OKSALA, Satu-Liisa PAUNIAHO (Tampere, Finland)
08:30 - 17:40 #11730 - Use of simulation to teach procedural sedation in the emergency department.
Use of simulation to teach procedural sedation in the emergency department.

Introduction: Procedural sedation and analgesia is an integral component of the skill set of the modern Emergency Physician, employed to enable a broad range of medical procedures to be tolerated by patients without undue pain or suffering. It is practised on a daily basis, to varying degrees and using varying techniques and drugs, in all UK Type 1 Emergency Departments (which have resus room facilities). It is important to note that procedural sedation is a form of anaesthesia, covering a continuum from anxiolysis through to (but not including) general anaesthesia. For it to be practised both effectively and safely it is vital to approach procedural sedation broadly as one would general anaesthesia, with a similar process of planning, pre-assessment and checks. Objectives: To develop an infrastructure that delivers high quality sedation and has provision for training and teaching both ED medical and nursing staff built-in. Materials & Methods: Emergency Medicine Registrars working in areas of the Emergency Department where conscious sedation is performed (the resuscitation room) were the participants in the procedural sedation simulation training. Prior to the training session, the participants read the Royal College of Emergency Medicine (RCEM) Procedural Sedation in Adults Clinical Audit 2015-2016. Their theoretical knowledge and experience were both then assessed in the following categories: previous sedation experience, knowledge of drug pharmacokinetics, number of previous rapid sequence intubations, management of common sedation complications, knowledge of equipment and presedation assessment and familiarity with departmental protocols and policies. They were then allowed to demonstrate 3 supervised procedural sedations using a high fidelity mannequin (SimMan3G) and rate their experience. Mean participant rating of the educational session was 4.75 (1 = poor, 5 = excellent) Result: 10 Emergency Medicine Registrars participated in the training. Mean participant rating of the educational session was 4.80 (1 = poor, 5 = excellent) Conclusion: Simulation provides an effective method for teaching procedural sedation in the Emergency Department to eligible Emergency Medicine Registrars. Further objective theoretical testing of knowledge is planned for the future in the form of an online module for self-assessment. However simulation provides an excellent constructivist method to assess practical skills.


Sergio B SAWH (London, ), Samer ELKHODAIR, Anna BUCKLEY, Alexander SCHUELER
08:30 - 17:40 #11589 - Use of the sbar in handovers from the ambulance service to the emergency department.
Use of the sbar in handovers from the ambulance service to the emergency department.

Introduction

One of the main causes of adverse events is communication failure. Handover from the ambulance service to the Emergency Department carries an even higher risk than other handovers because the patient is transferred from one service to another and there is only one opportunity to exchange information. Gaps in communication and information loss from handovers could lead to a prolonged stay in the Emergency Department and reduced patient safety. One recommended way to improve the handover is the use of a structured approach. The SBAR (Situation, Background, Assessment, and Recommendation) is recommended by the WHO and is also incorporated in the Dutch nation-wide guidelines for ambulance personnel. In our experience, there is a lack of adherence to this guideline. The primary objective of this study is to evaluate how often the SBAR is used, and if so, whether the SBAR is used appropriately. The secondary objectives are to evaluate the influence of the use of the SBAR on the agreement between the probable diagnosis after handover and the final diagnosis, time of stay at the ED and the number of diagnostic tests used. This study is part of a larger project to improve handover, and after collection of the data there will be an intervention which consists of an e-learning and training to improve handover and use of the SBAR.

Methods

Data on handovers are collected through observations in 4 hospitals in Amsterdam, between February and May 2017. We will also review the patient records retrospectively. Data will be analyzed using SPSS version 24.

Results and Conclusion

Data from this study will be available in May.


Zwaan ESTHER (Amsterdam, The Netherlands), Holleman FRITS
08:30 - 17:40 #11518 - Usefulness of N-acetylcysteine in xenobiotic hepatotoxicity.
Usefulness of N-acetylcysteine in xenobiotic hepatotoxicity.

The Authors describe two case of hydrocarbons ingestion for suicidal purpose. The first case concerns a caucasic male, aged 19, arrived in ED at 8:44 am because of ingestion of 200 mL of turpentine almost 2 hours before with suicidal purpose.  Personal history was free from relevant pahologies or others events. Known abitual use of THC.

In ED the patients was sleepy (GCS 14), a little bit oppositive, but with nothing in particular at examination.

From the nasogastric tube positioned in ED was aspirated 110 mL of milky fluid with mucus and blood.

 

The patient was treated with PPI and H2 inhibitors, for gastric protection, and N-acetilcysteine 10 gr (150 mg/Kg) in the first 90’ and 3.5 gr every 4 hours for at least 3 days. Airways protection, in case of worsening of Glasgow Coma Scale, and monitoring hepatic and renal function and for acid-base balancing, in case of acid diarrhea, were also recommended.

 

The patient was trasferred in ICU for intensive monitoring and care. Here he result positive for assunction of THC and amfetamine.  At first chemistry sample, increasing in WBC (12500/mmc)  was the only evident find. The EKG revealed an incomplete Right Bundle Branch Block with PR 121 ms, QTc 419 ms.

 

24 h after , the patient, was transferred to psychiatry unit for ordinary follow up and further observation.

At 48 h control, chemistry was invariated and EKG was normal with PR 122 ms, QTc 414 ms. MOF signs were never observed

 

The second case concerns a girl who came to the ED with suggestive symptoms of vertebrobasilar stroke with stable vital signs . She was subjected to CT with negative results and admitted to Stroke Unit . 1 hour after the access , vital signs became unstable with signs of Multi Organ Failure , diarrhea, halitosis and hydrocarbons alithosis; chemistry revealed a complete anticoagulation. After a toxicological consulting, she was subjected to treatment with N-acetilcysteine and support therapy for 5 days, with a slow return to normal blood parameters and alert neurological status . She was transferred to Psychiatryc Department after 10 days. The systemic toxicity caused by ingestion of hydrocarbons varies depending on the compound , but generally causes ataxia , lethargy , headache, coma . Sensitization of the myocardium to catecholamines can cause cardiac arrhythmias , not observed in this case . Liver and kidney toxicity and bleeding disorders are normally observed . We suppose that the hepatic toxicity has been prevented , in this case , by the administration of N-acetylcysteine

Conclusions: although actually n-acetylcysteine therapeutic indications are quite limited, our experience suggests that n-acetylcysteine may be used in a wider number of cases preserving hepatic integrity and functionality in in those patients who ingested substances with potential hepatotoxic effect.


Giorgio RICCI, Massimo ZANNONI (VERONA, Italy), Gianni TURCATO, Chiara BOVO, Lucia ANTOLINI
08:30 - 17:40 #11941 - Usefulness of the brest score to predict acute congestive heart failure in emergency department.
Usefulness of the brest score to predict acute congestive heart failure in emergency department.

Dyspnea is among the leading causes of presentation to the emergency department (ED). There is an urgent need to develop simple tools to help physicians to recognize the diagnosis of acute congestive heart failure (ACHF) promptly.   

The aim of our study was to assess the usefulness of a simple score to determine an eventual AHCF for patients presenting to the ED with dyspnea.

 

Methods : We included all patients presenting to the emergency with dyspnea and for whom we performed  a transthoracic ultrasound and/or NTproBNP to confirm the diagnosis of ACHF.  We analyzed their epidemiologic data, outcome and classified them according to the BREST score to determine whether the score was reliable.  

 

Results : We included 88 patients (the study is still on). The mean age was 70.58 with a predominance of male gender 52.4%. Sixty five pourcent of our patients had a history of hypertension. A NYHA score of 3 and over was detected in 58.4% of our group. In 57.2% of the cases, patients presented acute respiratory distress  (SpO2<91%). According the BREST score : 4.8% of the patients had a low probability of AHF (<4),40.4% were with intermediate probability (4-8), 54.8% were with high probability of AHF (>9). Only 18,8% of patients were admitted to the cardiology department. Six patients died from cardiogenic shock.

Conclusions : BREST score is a good predicting score for acute congestive heart failure diagnosis as it uses simple items enabling the emergency physician to lauch the mangement process rapidly.


Sana LAHMAR, Zied GUERMAZI (Trévenans), Ahmed GUESMI, Wiem DEMNI, Ines BELGACEM, El Moez BEN OTHMANE, Nour El Houda NOUIRA, Maamoun BEN CHEIKH
08:30 - 17:40 #11384 - Usefulness of x-ray order for ankle trauma by the triage nurses.
Usefulness of x-ray order for ankle trauma by the triage nurses.

The aim was to determine the effect of nurse triage initiated x-ray using Ottawa Ankle Rules (OAR) in the management of ankle sprain. This monocentric, observational study was conducted in a before and after study implementation phases. Seventy patients were eligible in each group (35±17). Mean waiting time was reduced by 41 minutes (p<0.008) and the length of stay by 48 minutes (p<0.001). Triage nurse initiated radiography using OAR decreases significantly the length of stay for ankle sprain


Baboo Irwin MEWASING (PARIS), Eric BURGGRAFF, Veronique LEFRANC, Anouck MINTANDJIAN, Patrick RAY, Pascal DEBOST, Rachel VERBBRUGGHE, Maelle VALENTIAN
08:30 - 17:40 #11006 - Utility of capnography monitoring and cardiac-lung ultrasound during hemodynamically resuscitation in a critical care patient. Prospective observational study.
Utility of capnography monitoring and cardiac-lung ultrasound during hemodynamically resuscitation in a critical care patient. Prospective observational study.

Background: Emergency ultrasound is a bedside, point of care, focused diagnostic procedure with aim to complete the physical examination. Cardiopulmonary monitoring is a key component in the evaluation and management of critically ill patients. Monitoring of exhaled carbon dioxide (CO2) in nonintubated patients is challenging. Capnography is the only device that displays a waveform of CO2 levels throughout the respiratory cycle. Analysis of this waveform is key to avoiding therapeutic errors.

Objectives: The primary goal is to determine the utility of cardiac-lung ultrasound and capnography in noninvasive monitoring of critical ill patients.

Patients and Methods: The cross-sectional study at Emergency Department of Hospital del Vinalopo prospectively evaluated 75 patients between March 2015 to February 2017. The attending physician of emergency medicine evaluated the patients through cardiac-lung ultrasound and monitoring with capnography waveforms. Finally, data were compared and quantitative and categorical variables were worked out along with other statistical analysis through estimated indicators.

Results:

The first examination performed during 15 minutes of initial assessment detect in 80% P=0.005) causes of instability in no traumatic patients. The sensitivity was about 82.5% (95% CI) and positive predictive value of 88.2%. During correlation between B patterns (lung ultrasound waves) and capnography values we obtained high correlation index (r=0.56; p≤0.001). The combined evaluation permits isolation of mechanical airway in 35% of patients with cardiac assessment during first evaluation.

The combined use of cardiac ultrasound parameters (cardiac output, pressure estimation and left ventricular diastolic function) and determination of EtCO2 permits in 23% of patients the invasive management and identifications of early signs of ventricular claudication (r=0.84; p≤0.001).

Conclusions:  This study demonstrates that focused emergency ultrasound and capnography waveforms may be useful for the diagnosis of several acute complications or situations with a high rate of mortality in critically care. Further education and implementation of capnography should take place to improve the use of this monitoring device for critically ill patients in the ED.


Julio ARMAS CASTRO (Elche. Alicante, Spain), Blas GIMÉNEZ FERNÁNDEZ, Juan Carlos REAL LÓPEZ, Laura FERNÁNDEZ CALVO
08:30 - 17:40 #10915 - Utility of Computed Tomography in Hemodynamically Unstable Patients with Blunt Trauma: Experience at a Tertiary Care Center.
Utility of Computed Tomography in Hemodynamically Unstable Patients with Blunt Trauma: Experience at a Tertiary Care Center.

Background: Emergent exploratory laparotomy is recommended for hemodynamically unstable blunt trauma patients who are suspected of having hemoperitoneum. However, given the unreliability of ultrasonography and rapid scan speed of computed tomography (CT), preoperative CT may be beneficial even in hemodynamically unstable patients with blunt trauma. We aimed to assess the bleeding site and hospital course of blunt trauma patients with hemoperitoneum who underwent the ‘CT first protocol’.

Methods: We enrolled adult blunt trauma patients (age ≥ 18 years) who underwent whole body trauma CT before surgery from February 2012 to October 2016. Patients with hemoperitoneum on CT were included and assigned to the hemodynamically stable or unstable groups.

Results: Among 136 patients with hemoperitoneum, 98 (72.1%) had intraperitoneal injury; the liver (60.2%) was the most frequently damaged site, followed by the spleen (23.5%), and mesentery (23.5%). The rate of intraperitoneal organ injury did not differ between the hemodynamically stable (n=101) and unstable (n=35) groups (72.3% vs. 71.4%, P = 0.92), although the rate of documented active internal bleeding was markedly greater in the unstable group (29.7% vs. 62.9%, P < 0.001). In the unstable group, 15 (42.9%) patients underwent emergent operation, 3 patients underwent embolization, and the remaining were treated conservatively.

Conclusions: Among hemodynamically unstable patients with hemoperitoneum, 28.6% had no documented intraperitoneal injury and >50% were treated without emergent operation, which suggests that careful CT scans might help clinicians to select patients with intraperitoneal injury requiring emergency operation and having an active bleeding source.


Soo-Han CHO (Seoul, Republic of Korea), Youn-Jung KIM, Won Young KIM
08:30 - 17:40 #11497 - Utilization and trans-sectoral patterns of care for patients admitted to emergency departments in Germany (INDEED).
Utilization and trans-sectoral patterns of care for patients admitted to emergency departments in Germany (INDEED).

Background

Patient numbers in Emergency Departments are steadily increasing and an adaption of health care structures to actual patient demands is highly required to assure adequate treatment. Reliable data on influencing factors on ED utilization and characterization of ED patients with regards to urgency, severity, diagnosis and patient pathways before and after an ED visit are currently not available in Germany and many other European countries.

Methods

Clinical hospital data from 15 to 20 EDs in Germany will be linked to routine ambulatory health care data of the Association of Statutory Health Insurance Physicians (Kassenärztliche Vereinigung, KV). The overall aim of INDEED is to facilitate trans-sectoral and interdisciplinary health services research of emergency care in Germany.

The primary objective of the project is to assess the trans-sectoral utilization of health care services of patients 2 years prior and 1 year after treatment in an emergency department. Patterns of adequate, inadequate and potentially avoidable care will be examined. The secondary aim is to identify patient clusters with comparable needs of health care provision. For the clusters and for individual patients INDEED will examine health care needs and gaps as well as factors that influence emergency department visits, disease progression, comorbidity and mortality. 

Results

The INDEED project starts on 1st of May 2017. First steps will be the recruitment of eligible emergency departments with standardized electronic documentation of ED-processes as well as the development of a data flow and data protection concept. At the EUSEM congress, the protocol of the INDEED project, involved partners as well as data concepts could be presented.

Conclusions

INDEED will be the first project in Germany to combine nationwide ED-data with data of ambulatory care to describe actual trans-sectoral patterns of care for ED patients. INDEED will facilitate to identify health care gaps and inadequate resource allocation with the overall aim to develop interventions for the adaptation of health care provision to existing patient demands.


Pr Anna SLAGMAN, Felix GREINER, Felix WALCHER, Michael ERHART, Christian GÜNSTER, Liane SCHENK, Natalie BAIER, Cornelia HENSCHKE, Reinhard BUSSE, Drepper JOHANNES, Lüpkes CHRISTIAN, Röhrig RAINER, Theresa KELLER, Thomas REINHOLD, Stephanie ROLL, Thomas KEIL, Pr Möckel MARTIN (Berlin, Germany)
08:30 - 17:40 #11318 - Utilization of a UK emergency department by care home residents 10 years on: a retrospective observational follow-up study.
Utilization of a UK emergency department by care home residents 10 years on: a retrospective observational follow-up study.

Care home (CH) residents have approximately 40-50% more accident and emergency (A&E) attendances compared to the general population. Studies have shown that many of these care home (CH) attendances are potentially avoidable, and may be unnecessary, possibly causing more harm than benefit to the patient. This study aims to determine the utilisation of the emergency department (ED) at the Royal Alexandra hospital (Paisley, Scotland) by local CH residents between January 1st and December 31st 2016 and to compare the results with those of a similar study conducted in the same hospital in 2006. 441 CH residents had 729 presentations to the ED. This represents 1.05% of total annual ED attendances. The average age was 80 years (30-104 years). 453 of these attendances were female amounting to 62%, with 46.2% attending between 9am and 5pm. Mean attendance was 2.0 CH patients daily. 34% attended in the evening and 20% attended overnight. 78% of patients were transferred by ambulance and the most common reason for attendance was trauma (N=228, 31.3%). Of the 729 patients transferred to the ED, 2 died in the department. 61.7% (N=450) of patients were admitted, 38% (N=277) were discharged and 0.3% (N=2) died. Of the 450 patients admitted, 63 died, 12 were still in admission, and the remainder had been discharged. 271 patients had a Do Not Attempt CPR (DNACPR) on presentation and 81 were issued during admission. In 377 patients, a DNACPR order was not found. Previous studies have shown that many of these CH ED attendances are unnecessary and potentially harmful to patients. This study sought to contribute data on CH resident presentations to the ED, which may have a role in developing future guidelines to reduce ED transfer in this vulnerable cohort.

 


Elisha KHOO (Glasgow, United Kingdom), Moroke IGUE, Paul MCNAMARA, Monica WALLACE, Iain YOUNG
08:30 - 17:40 #10606 - Validation of the decision groups in the patients with dengue fever: a study during 2015 outbreak in Taiwan.
Validation of the decision groups in the patients with dengue fever: a study during 2015 outbreak in Taiwan.

Background:

Dengue fever (DF) is one of the most important mosquito-borne viral diseases in the tropics and sub-tropics. The management of DF is suggested to be divided into decision Group A, B and C by World Health Organization; however, its usefulness in predicting mortality is still unclear, and therefore we conducted this study to clarify this issue.

Methods:

We conducted a retrospective case-control study by recruiting DF patients from 2015 outbreak in the studied hospital in Taiwan. Demographic data, vital signs, clinical symptoms and signs, co-exiting morbidities, laboratory data, decision groups, and 30-day mortality rates were included for the analysis.

Results:

In total, 2,358 DF patients was recruited into this study with the overall 30-day mortality rate of 1.44% (34/2,358). The 30-day mortality rate in decision Group A, B, and C was 0% (0/1469), 0.5% (4/824), and 46.2% (30/65), respectively. Compared with Group A, there was a significantly higher mortality risk in Group C(odds ratio [OR]: 1475.0, 95% confidence interval [CI]: 194.3-11197.9) and a higher mortality trend in Group B (OR: 7.2, 95% CI: 0.8−64.5). The area under the curve of the variable of Group C was excellent (0.920, 95% CI: 0.850-0.990). The sensitivity, specificity, positive predictive value, and negative predictive value for predicting 30-day mortality in Group C was 85.3%, 98.8%, 50%, and 99.8%, respectively.

Discussion:

Decision Group C has a good predictive value for 30-day mortality in this study. Further studies including validation in other nations and difficulties of the classification of decision groups are warranted.

 


Wei-Ta HUANG (Tainan, Taiwan), Chien-Cheng HUANG
08:30 - 17:40 #11869 - Validity of the Canadian Triage Acuity Scale in a Tertiary Children's Hospital in Israel.
Validity of the Canadian Triage Acuity Scale in a Tertiary Children's Hospital in Israel.

Introduction: In 2015, the Israeli Ministry of Health issued national guidelines demanding the use of a five-level triage system in pediatric emergency departments (EDs). No studies to date have evaluated the performance of a triage scale in Israel. The present study aimed to evaluate the validity of the Pediatric Canadian Triage Acuity Scale (PedCTAS) in the ED of a tertiary children's hospital in Israel.                                           

Methods: A retrospective cohort study of all children visiting the pediatric ED between 1.1.2011 and 31.12.2015 was conducted. Primary outcome was the proportion of patients hospitalized in each triage level. Secondary outcomes included the proportion of patients admitted to ICU, ED length-of-stay and proportion of patients left without being seen (LWBS) in each triage level.

Results: A total of 83,605 patients were included in our study. Triage levels 1-5 included 533 (0.6%), 4428 (5.3%), 46 461 (55.6%), 28 510 (34.1%), and 3677 (4.4%) patients, respectively. A descending order of hospitalization proportion was demonstrated, with values of 70%, 50%, 28%, 15% and 12% for Ped-CTAS triage levels 1, 2, 3, 4 and 5 respectively. Admission proportions to ICU were 24.2, 3.05, 0.24, 0.05, and 0.05% for PedCTAS levels 1, 2, 3, 4, and 5, respectively. The proportions of LWBS were 0.001, 0.002, and 0.005% for triage levels 3, 4, and 5, respectively. LOS was shorter as the triage level increased from 2 to 5

Conclusion: Triage level was predictive of hospitalization, admission to the ICU, and proportions of LWBS and LOS in the ED. The findings suggest validity of the PedCTAS in this cohort.


Raviv ALLON, Oren FELDMAN (Ramat Gan, Israel), Anna KARMINSKY, Carmit SHTEINBERG, Ronit LEIBA, Itai SHAVIT
08:30 - 17:40 #11800 - Value of simplified acute physiology score in predicting mortality of severe community-acquired pneumonia patients.
Value of simplified acute physiology score in predicting mortality of severe community-acquired pneumonia patients.

Background:

Severe community-acquired pneumonia (SCAP) remains a leading infectious cause of death throughout the world. International guidelines recommend a severity-based approach to management in SCAP patients in emergency department .The aim of this study was to compare the performance characteristics of the most widely recommended severity scores for predicting mortality in severe community-acquired pneumonia.

Methods:

Retrospective study over 3-year period that included ICU-admitted patients with SCAP diagnosis. Pneumonia severity and ICU severity scoring indices including CURB65, the Pneumonia Severity Index (PSI) score, PICO score, Acute Physiology and Chronic Health Evaluation (APACHE) II score, simplified acute physiology score II (SAPS II)  and  Sequential Organ Failure Assessment (SOFA) score were calculated for each patient , and clinical variables were also recorded during the first 24h.

Results:

The cohort included forty-two SCAP patients with 70% in-hospital mortality. The mean age was 67 + 15 years with a sex ratio of 2. Medical history: hypertension (28,6%), diabetes (38%) tobacco (60%), COPD (50%), chronic respiratory failure (28%). patients had cumulated more than three comorbidities in 50 % of cases. The mean value of PSI was about 120+38, class IV-V: 76.2%, the CURB 65 score was greater than or equal to two in 76% of cases, the mean value of APACHE II score was 17+6, SAPS II score was 44+16, PICO score was 3+1 and  SOFA score was 4,5+3. Each severity score was correlated to the mortality with p<0.05. SAPS II has the highest sensitivity and specificity in predicting mortality in SCAP, followed by PSI and SOFA score. The areas under curve (AUC) were 0.97; 0.85; 0.82 and 0.76 for SAPS II, PSI, SOFA and PICO scores, respectively.

Conclusions:

SCAP remains a frequent condition of morbidity and mortality. Pneumonia severity scales are important to predict the prognosis in order to improve triage decisions and guide ICU admissions of patients with CAP whereas prognostic scores in ICU severity scales especially SAPS II were superior in predicting SCAP mortality.

 


Fatma HEBAIEB (Ariana, Tunisia), Eya HNIA, Salah SNOUDA, Raja FADHEL, Nawres BEDOUI, Ameni SGHAIER, Moez KADDOUR, Hassen BEN GHEZELA
08:30 - 17:40 #11958 - Value of systolic time intervals in the prediction of 30 days mortality after hospital discharge in Acute Heart Failure patients.
Value of systolic time intervals in the prediction of 30 days mortality after hospital discharge in Acute Heart Failure patients.

Background: Acute heart failure (AHF) is one of the leading causes of unscheduled hospitalization and is associated with frequent readmissions and substantial mortality. Simple and noninvasive measurements of systolic time intervals (STI) could be helpful to predict these complications in patients admitted to the emergency room (ER). The present study assessed the prognosis performance of STI in AHF patients. 

Patients and methods: We included all patients over 18 years old admitted to the ER for AHF. The diagnosis of AHF was determined on the basis of clinical examination, echocardiography, and brain natriuretic peptide value. Measurement of STI included the pre-ejection period (PEP), left ventricular ejection time (LVET), and systolic time ratio (STR=PEP/LVET). STI were determined by thoracic bio-impedance method, at admission in all included patients. Survival status data at 30 days was prospectively collected. The values of STI were compared between survivor and non survivors patients in order to determine their prognostic value. 

Results: A total of 500 AHF patients were included, with a mean age 68,41 ± 12 years, sex ratio (M / F) 1,04. Compared to survivors, Non survivors patients had higher STR (48.7 ±17 vs 43.2±11, p<0.01) values. LVET and PEP values were not significantly different between both groups. 

Conclusion: Only STR value could be considered as a meaningful non invasive method to predict mortality 30 days after hospital discharge in AHF patients.


Kaouthar BELTAIEF, Nader BEN OTHMEN (Monastir, Tunisia), Noussaiba AZAIEZ, Lassaad BOURAOUI, Adel SEKMA, Nasri BZOUIECH, Med Amine MSOLLI, Med Hbib GRISSA, Hamdi BOUBAKER, Wahid BOUIDA
08:30 - 17:40 #11837 - Vogt-koyanagi harada syndrome.
Vogt-koyanagi harada syndrome.

Vogt-Koyanagi-Harada Syndrome

Introduction:

Vogt-Koyanagi-Harada (VKH) disease is a multisystemic disorder characterized by granulomatous panuveitis with exudative retinal detachments that is often associated with neurologic and cutaneous manifestations. VKH disease occurs more commonly in patients with a genetic predisposition to the disease, including those from Asian, Middle Eastern, Hispanic, and Native American populations.

Case description:
We report a case of a 20 years old African male patient, previously healthy presented with a history of fever, productive cough, vomiting, bilateral eye redness and blurring of vision of 7-10 days duration.
Decreased hearing abilities for 10 days as well as History of gradual marked diminution of vision for 2 days. Patient denied any history of Eye Trauma or previous Ocular surgery.
On examination: afebrile, satiable vital signs, conscious, oriented.
Eye exam: revealed bilateral injected bulbar and palpebral conjunctivae
Pupils: mid dilated, sluggish reactive to light.
Slit lamp examination: revealed mild bilateral Corneal oedema.
Keratic precipitates on back of Cornea.
Fundus examination: bulbous exudative subtotal retinal detachment with engorged
Retinal veins and normal optic disc.
Patient was admitted under Ophthalmology care, started on medriatic cycloplegic eye drops, And Oral prednisone.
Patient was assessed by Rheumatologist, recommended to start immune suppressive
Medications.
Continued follow up with Ophthalmologist, with mild to moderate improvement.

Conclusion
We here discuss a case of Vogt- Koyanagi- Harada syndrome which is a rare disease and rare to find in Africans.
we here report this case to be considered in differential diagnosis of 'red Eye
Syndromes especially that preservation of vision is time related and misdiagnosis
Can lead to permanent loss of vision.


Zenab ABDEL RAHMAN (Doha, Qatar)
08:30 - 17:40 #10696 - Waveform Capnography in the Emergency Department Between Theory and Practice.
Waveform Capnography in the Emergency Department Between Theory and Practice.

Waveform Capnography in the Emergency Department Between Theory and Practice

Introduction:  Waveform capnography is slowly emerging as the standard of care in emergency medicine; it is a crucial element in monitoring quality of CPR (Cardio-Pulmonary Resuscitation), and the assessment of ROSC (Return of Spontaneous Circulation), according to ALS (Advanced Life Support) recommendation. There is not much data about the use of waveform capnography in Hamad General Hospital (HGH), the biggest Teaching University Hospital in Qatar.

Objectives: To evaluate the use of waveform capnography by Emergency Physician (EPs) in HGH, Qatar.

Method:  We conducted a survey for the EPs through an online questionnaire to evaluate their current practice and experience using waveform capnography in the ED.

Results: 93 out of 100 EPs responded to our survey, a third of them were fellows while participation from residents, registrars, and consultants were 13.98%, 27.96%, 24.73% respectively.  Although majority of responders (87.1%) are aware that waveform capnography is available in our department, only 10% are ‘always’ using it (more than 90% of the time). 31% ‘rarely’ use the device and spuriously 12.9% never use it.

80% of the participants stated that they use waveform capnography for confirming successful endotracheal intubation. 66% claims to monitor ongoing CPR and intubated patients with end tidal CO2. Two third of the responders considered omitting waveform capnography monitoring in these 3 clinical circumstances as substandard practice.  Interestingly, only half of the responders think it is compulsory during transfer of intubated patients and when undertaking procedural sedation.

Most of the participants think that lack of training and awareness of equipment availability is the major reasons for not using waveform capnography – this accounts for around 60% and 48% respectively.  Almost all responders think capnography training is important.  The preferred way seems to be a workshop or blended (online and workshop), while a lecture is rated as the least favourable.

Conclusion:  Although many EPs thought it is fundamental to use capnography in certain circumstances, it is not commonly used, and this is attributed to lack of awareness of availability and the lack of training.  According to our EPs some sort of education in the form of online and physical training is probably the best way to spread the knowledge about waveform capnography, and reap the benefit of its use in our department.

Recommendation: Based on these findings we are currently working on improving our orientation package for new doctors that includes the expected use of waveform capnography. We are also working on some Departmental in-house training modules for existing doctors, perhaps incorporating them in our airway management and mechanical ventilation workshops. We encourage all ED around the world to do the same if they are not already doing so.    

 

 

 

 


Mohammed ALHUSSEIN (DOHA, Qatar), Mohamed QOTB, Alhady YUSOF
08:30 - 17:40 #11503 - Wellens’ syndrome: particular form of acute coronary syndrome.
Wellens’ syndrome: particular form of acute coronary syndrome.

Introduction:

Wellens syndrome is a special electrocardiographic (ECG) entity of the acute coronary syndrome without ST segment elevation in relation to a critical stenosis of the proximal left anterior descending coronary artery (LAD). Patients with Wellens’ syndrome have a major risk of developing an anterior myocardial infarction. Therefore, it is essential to the emergency physician to be able to recognize the ECG criteria of this syndrome.

Case report :

A 53 year-old-male presented to the emergency department (ED) with retrosternal chest pain radiating to left arm since three days before ED admission. He had a 10 pack year smoking history and he had no family history of coronary artery disease.

He had normal physical examination findings. An ECG performed immediately revealed biphasic T-waves from leads V1 to V4. The basic laboratory tests including cardiac enzyme testing were unremarkable; a chest X-Ray scan showed no intrathoracic pathology. The diagnosis of Wellens’ syndrome was made. A dual anti-platelet (aspirin and clopidogrel) and anti-coagulant (subcutaneous low molecular-weight heparin) medication was given.

One hour after admission, the patient presented another episode of precordial pain.  An ECG performed showed disappearance of the biphasic T waves which became positive with ST segment depression in inferior and basal leads.

The patient was transferred to cardiac intensive care unit for emergency coronary angiography, which showed subocclusive stenosis of the proximal left anterior descending coronary artery. A stent was set up with good angiographic result.

Conclusion:

Accurate identification of patients with Wellens’ syndrome allows more rapid and appropriately aggressive management. It becomes imperative that the emergency physician recognize these patients to prevent prolonged stays in ED and inappropriate conservative therapy.

 


Hanen GHAZALI (Ben Arous, Tunisia), Ahmed SOUYAH, Aymen ZOUBLI, Anware YAHMADI, Rania JEBRI, Najla ELHENI, Sawsen CHIBOUB, Sami SOUISSI
08:30 - 17:40 #11647 - Wembley national stadium hyper-intensive cardiac resuscitation pathway.
Wembley national stadium hyper-intensive cardiac resuscitation pathway.

Coronary Heart Disease (CHD) is the leading cause of death worldwide, with heart disease leading to more than a quarter of all deaths in the UK. Most deaths from CHD are caused by a myocardial infarction (MI), and can present to hospitals every three minutes. Unfortunately in the UK Out-of-Hospital Cardiac Arrest (OHCA) has a poor survival rate (less than 1 in 10).

Studies have shown an increased incidence of OHCA in spectator sports compared to population measures. Sudden cardiac death (SCD) remains the leading cause of death in athletes during sporting activity. The importance of cardiac arrest in sport was highlighted recently by its inclusion in the European Resuscitation Council (ERC) 2015 Guidelines.

This review describes the cardiac resuscitation protocol that has been developed by the Football Association’s Pre-Hospital Emergency Medicine team at Wembley National Stadium, London. Wembley has implemented an integrated three-phase response to cardiac arrest in the stadium and on field-of-play:

Phase 1.  Immediate dispatch of rapid-response multi-disciplinary resuscitation team with early defibrillation & mechanical CPR

Phase 2. Advanced Resuscitation 'Pit Stop' in the Stadium medical facility resuscitation room.

Phase 3. Direct Transfer to ECMO Centre for Artificial Circulatory Support & Cardiac Intervention.

In addition to this, an established training programme is undertaken for response in the unique clinical areas of the stadium (Immediate Care in Event medicine - ICEM) and the sporting field-of-play (Emergency Care on Pitchside - ECOPS) to improve consistency and quality of protocol delivery and to address and manage human factors.

The implementation of this pathway has already produced successful outcomes.


Sam BOTCHEY (London, United Kingdom), Mike PATTERSON, Alex ROSENBERG, Mark CUTLER
08:30 - 17:40 #11498 - What are AIMS and what do their users think of them?
What are AIMS and what do their users think of them?

Background

Acute alcohol intoxication (AAI) is a common cause for emergency department (ED) attendance and places a substantial burden on emergency care services.

 

What are Alcohol Intoxication Management Services (AIMS)?

AIMS are designed to receive, treat, and monitor intoxicated patients who would normally use emergency care services. They are usually located close to night time economy (NTE) precincts characterised by excessive intoxication and are open at regular times when the number of people drinking to excess peaks (e.g. Friday and Saturday evenings).

 

The place of AIMS in the NTE is not yet well understood. For example, it is not known whether the care they offer is acceptable to users. The purpose of this study was to explore user perspectives of AIMS.

 

Method

We identified six AIMS with diverse structures and processes in cities across the UK to compare. We undertook 19 semi-structured telephone interviews with AIMS users in the UK to explore their experiences and perceptions of AIMS care. Interviews informed the development of a brief questionnaire for completion by users when exiting the service (current n>140). Items included self-reported reason for attendance and satisfaction.

 

Results

AIMS are diverse in form and configuration but share some common features. Housed in either fixed sites or mobile units, AIMS are often staffed by multiple agencies, including police, NHS paramedics and nurses, private hire medics and first aiders, faith-based volunteer groups, and substance misuse agencies.  Some AIMS are charity funded and volunteer led, while others involve collaboration between the local police, health and ambulance services.

 

Interviews with AIMS users revealed most perceived the staff and environment of AIMS to be appropriate for their level of need. In general, users reported feeling safe whilst in the service, despite some uncertainty in their recollection of who had made key decisions on their behalf (e.g. around attendance and discharge).  Just over half of survey respondents indicated their attendance was intoxication-related and over a third reported minor injury. High levels of satisfaction were reported across all aspects of care. The majority preferred to be treated in the AIMS, compared to treatment elsewhere or going home.

 

This presentation will report further characteristics of the AIMS and full analysis of interview and survey data.

 

Implications

AIMS offer an alternative to ED attendance that appear acceptable to users. However, there is marked variation in the services provided. The project will evaluate the effectiveness and cost effectiveness of AIMS involving observations and interviews with frontline staff and analysis of routine data and economic modelling which will estimate the likely effect of a national rollout. The findings of this evaluation will be relevant to many practitioners and organisations across the world who are exploring different ways to divert people with AAI away from emergency care services. 


Andy IRVING (Sheffield, United Kingdom), Penny BUKYX, Simon MOORE, Steve GOODACRE, Alicia O'CATHAIN, Yu-Chiao WANG
08:30 - 17:40 #11540 - What we do and What would PECARN do?
What we do and What would PECARN do?

Objective: The aim of our study is to determine head CT scan necessity in paediatric head trauma patients and to compare decisions of emergency medicine physicians (EMP) and PECARN scale suggestions on head CT scan necessity.

Methods: Our study was conducted retrospectively between 07/01/2014 and 12/31/2014 at Istanbul Dr Lutfi Kırdar Kartal Training and Research Hospital. All patients under the age of 13 with head injury because of fall were included.

Registry of all patients was analysed and PECARN scale was applied to each patient’s data. Suggestions of PECARN scale were noted. Head CT scans were reported by radiologist, if any head CT scan was performed. EMP’s decision and PECARN scale suggestions were compared. Patients who should had CT scan by PECARN scale suggestions but had no imaging were contacted and asked about any other reasons to seek medical care after the fall in question.

Patients with inadequate data, age older than 13, history of falling from a moving vehicle, Glasgow Coma Scale (GCS) 13 and under, diseases which cause altered mental status and in use of anti-coagulant drugs are excluded.

Results: When PECARN suggestion and EMP’s decisions of CT necessity compared; two applications showed concordance (p=0.055; p>0.05). Concordance analysis of two results are determined as 76.6% (Kappa coefficient: 0.766). EMP’s decisions had 88.76% sensitivity, 91.09% specificity, 78.22% positive predictive value, 95.74% negative predictive value and 90.48% accuracy.

Conclusion: In assessment of children with minor head injury EMP decision and PECARN scale were found coherent and sufficient. In patients with minor paediatric head injuries, majority of performed CT scans according to either PECARN scale suggestions or EMP decisions showed no intracranial pathology. There is a need for more specific methods to provide more accurate assessment. Instead of early decision of CT scan, observation of patient can reduce radiation exposure but cost effectivity of this approach should evaluate by further studies.


Gokhan EYUPOGLU (Bitlis, Turkey), Eren GOKDAG, Fatma Sari DOGAN, Ozlem GUNEYSEL
08:30 - 17:40 #11419 - What's up with my tongue, Doc?
What's up with my tongue, Doc?

What's up with my tongue, Doc?

The Emergency Hospitalary Deparments (EHD) often become major quick gateway of access for many healthcare system users in case of banal or commonplace pathology, and also a medical consultation looking forward a quick diagnosis. To deal with this situation, emergency physicians stand up as the first evaluator of this pathology, needing to be able to recognize between urgent conditions or potencially fatal pathology and what is not.
Oral symptons is a common complaint in EHD where the recognision of the pathology prevents from unnecessary further work up.
We present a representative number of cases with an abnormally colored tongue as unique symptom and reason for consultation.
Case 1: 67 years old patient active smoker, long term haemodialysis user who presents a blackish colored tongue with no other symptomatology. This is a black hairy tongue, a bening pathology due to a bacterial overgrowth wich affects the back of the tongue with papilomatosis structure with blackish colored in variable intensity and associated with bad oral hygiene, use of mouthwash
containing oxidising agents and any bismuth medications, as well as tobacco and other process with reduced tongue mobility.
Case 2: 71 years old patient with high blood pressure, atrial fibrillation with oral anticoagulation treatment with acenocoumarol and hyperlipaemia, presented to the EHD with a blackish tongue and reddish cervical spots with 12 hours of evolution. A tongue haematoma was identified as the result of a acenocoumarol overdosage and a secondary neck affectation due to haematoma evolution. It is a well-known fact that acenocoumarol has a narrow therapeutic range and spontaneus haemorrahge may be the first symptom of a acenocoumarol overdosage and in certain cases trigger severe situations.
Case 3: 38 years old patiente with immunosuppressive therapy for a Crohn's disease showing at the EHD a pink of color raspberry intense tongue since the day before. In anamnesis, a school-age daughter with Strep throat. Scarlatina, transmitted through contact with saliva, can vary tongue coloration, whitish at first, and evolve to a strawberry tongue, white coating on the tongue, or prominent red bumps on the back of the tongue.

Conclussions:
The Emergency Hospitalary Deparments should not be a quick diagnosis tools for banal pathology nor to advance processes with delayable diagnostic tests. In turn, medical expertise in this cases of uncommon but banal pathology is a key cornerstone to discern a severe process and a real emergency.


Alvaro MARTIN PEREZ (Badajoz, Spain), Concepción DE VERA GUILLEN, Rosario PEINADO CLEMENS, Miguel Angel RUIZ SANZ
08:30 - 17:40 #11924 - When diagnosis gets twisted.
When diagnosis gets twisted.

Introduction: Torticollis refers to congenital or aquired involuntary neck twisting and head secondary to contraction of the neck muscles combined with limited range of neck motion. It is an acute or chronic clinical finding in wide spectrum of disorders and could be seen in pediatric population at all ages. Diagnostic procedures are limitating. In case of  acquired torticollis, neuroimaging plays an important role.  We present a case of torticollis in preschool child caused by the expansive process in cervical spine.

Case presentiation:  A 6-year old girl was admitted to our Emergency department (ED) due to pain and neck stiffness. Symptoms occured acute, eleven days before admission, when she was examined for the first time in other clinic. Although a girl trains gimnastics, no acute trauma or cold draft preceded. Nonsteroidal anti – inflammatory medicaments were initially administered. Five days later her symptoms were still present with no active neck movement. At the time, she had cervical limphadenopathy and sore throat therefore antibiotic therapy was administered after taking nasopharyngeal culture which came positive for Streptococcus pyogenes. Three days later, mother noticed that girl had difficulty with speech and discrete tongue thickening and deviation. At the time of admission to ED, mild neck pain was present with active and passive neck movement. Heteroanamnesis revealed that girl had recently visited osteopath to reveal neck pain. Neurological exam, except from mentioned above, was normal. Neuroimaging of head and neck showed expansive collection in cervical spine between C2 and C5 with deviation of cervical medulla. Hemilaminectomy was performed and collection was evacuated. Pathohistological analysis of evacuated tissue was suggestive for organized hematoma or hemagioma. Three months after surgery the girl has no signs of recurrence.

Conclusion: Differential diagnosis of torticolis is wide.  Although rare, the process in cervical spine should be considered in etiology of aquired torticollis in children - especially in persistent or recurrent cases.


Tena TRBOJEVIC, Lea MIKLIC, Tena TRBOJEVIC (Zagreb, Croatia)
08:30 - 17:40 #11002 - When electrocardiogram reveals metabolic disorder.
When electrocardiogram reveals metabolic disorder.

Introduction:

Electrocardiogram is indicated in multiple situations. It reveals ischemia, hypertension, metabolic disorders etc...

Hypokalemia is a frequent electrolytic disorder leading to life-threatening imbalance. Emergency restitution treatment must be associated with a rigorous etiological investigation.

 

Observation:

We report the case of a 60-year-old smoking patient admitted to the emergency department for dizziness and weakness. He reported no significant medical history. Physical examination found: GCS 15, normal temperature, respiratory rate 14cpm, heart rate 77bpm, blood pressure 100/50 mmHg and blood sugar was 170mg/dl. Cardio-pulmonary and abdominal examinations were normal. There was no neurological sign. An ECG was performed revealing regular sinus rhythm at 62 bpm, diffuse and deep ST segment depression and prolonged QT intervals (600 ms) with the presence of a U wave. Based on these electric signs, hypokalemia was suspected and confirmed on point of care gazometry (kalemia: 1,8 mmol/L). It also revealed a metabolic alkalosis (pH=7.68, pCO2=73 mmHg and HCO3->60 mEq/L)Laboratory tests confirms the metabolic disorders: glycemia= 9.4 mmol/L, natremia=134mmol/L, kalemia=1.7 mmol/L, calcemia=2.43 mEq/L, Chloremia <50mEq/L and creatinine=400 mmol/L). The hepatic and pancreatic findings were normal.The treatment was initiated rapidly: hydration with 6 liters per day of isotonic saline solution and intravenous potassium replacement (1 g per hour via a central venous catheter). The progression was favorable with normalization of serum potassium, renal function and acid-base balance.The etiological investigations reveal pyloric stenosis confirmed by oeso-gastroduodenal transit (Digestive fibroscopy was refused by the patient). Pump proton inhibitors were prescribed.The patient was discharged home after 4 days with an appointment to follow up with a gastroenterologist.  

Conclusion:

Electric findings may reveal life-threatening metabolic disorders such as severe hypokalemia. Features such as deep ST segment depression should always be kept in mind thus hypokalemia vigorously be managed to achieve early recovery of patients with improved outcome.


Ines CHERMITI, Dorra RIDENE (Ben Arous, Tunisia), Hanène GHAZALI, Rihab DIMASSI, Monia NGACH, Lyna JEBRI, Najla EL HANI, Sami SOUISSI
08:30 - 17:40 #10988 - When pain and clinical do not match: a case of spontaneous gas gangrene involving retroperitoneum.
When pain and clinical do not match: a case of spontaneous gas gangrene involving retroperitoneum.

Background: Spontaneous gas gangrene is a type of Clostridial Myonecrosis usually determined by the hematogenous seeding to muscles of Clostridium Septicum from a gastrointestinal portal of entry. Chemotherapy, neutropenia and lymphoproliferative disorders are considered predisposing factors. Diagnosis is driven by fever, severe pain not linked to trauma and generally localized at an extremity, detection of air within soft tissues (x-ray, CT or MRI) and isolation of Clostridium Speticum in blood samples. Fatal outcome concerns 67-100% of patients, generally within 24 hours. Opportune treatment is based on surgical debridment and intravenous broad spectrum antibiotic therapy (e.g. Piperacillin-Tazobactam). Case report: A 54 years old woman presents to the ED complaining epigastric pain, nausea and fever (38 °C). In history bilateral salpingo-oophorectomy; recent quadrantectomy for breast cancer currently in treatment with chemotherapy;  migraine; hypothyroidism. The clinical exam reveals soft abdomen, sore and tenderness in right hypochondrium and epigastrium, no signs of peritonism, normal peristalsis, pain at the compression of the left calf. Subcutanoeus Enoxaparine 6000 UI and intravenous Phloroglucinol 40 mg, Paracetamol 1 g, Ketoprofen 2,5 mg,  Morphine 3 mg, Fentanil 0,05 mg are administered without benefits. Laboratories point out severe neutropenia (WBC 1860/mm3, 29% neutrophils), elevated CRP (4,8mg/dL), Troponin 268ng/L and GPT 35UI/L. No ischemic alterations at the EKG. Chest and abdomen x-rays show elevated left emidiaphragm, accentuation of bronchovascular markings and small air-fluid levels with coprostasis particularly in distal colon. The inconsistency between pain and clinical signs leads to hypothesize intestinal ischemia. IV broad spectrum antibiotic and antimicotic therapy, G-CSF stimulation and fluids integration are started. Angio-CT of the abdomen detects cecum saccate perforation and presence of air extended from right ileo-psoas to right thigh, involving omolateral external iliac and femoral veins. The patient is bringed urgently to the operating room to perform a right emicolectomy and right ileo-psoas and inferior extremity fasciotomy. Despite prompt treatment and transfer in ICU in less than 24 hours, patient's condition worsen to death. PCT 178 ng/mL and blood culture positive for C. Septicum confirm the diagnosis of spontaneous gas gangrene. Conclusion: As life-threatening muscular infection, spontaneous gas gangrene needs fast diagnosis and treatment. The absence of scores and algorithms helping in detecting nectrotizing soft tissue infections highlights the importance to maintain high the suspect of these diseases. This case underline the key-role of inconsistency between pain perception, regardless the localization, and clinical manifestation in generating this suspect, especially when predisposing factors are present.


Francesca MORI (MODENA, Italy), Marina BUDA, Brugioni LUCIO, Daniela VIVOLI, Francesca DENIEDERHAUSERN, Niki AMADORI
08:30 - 17:40 #11055 - Where is pain? I did not expect to find this!
Where is pain? I did not expect to find this!

PERSONAL HISTORY AND REASON FOR INQUIRY

We are facing a case of abdominal pain for three days of evolution in a young patient of 39 years without clinical history of interest. The pain is very localized at the level of the hemiabdomen right, being the differential diagnosis main colic renal versus acute appendicitis.    

 

PHYSICAL EXAMINATION

The patient presented with TA 130/70. FC: 100 lpm. Temperature of 37.5 and 98% basal O2 Sat. His general condition is good, complains of pain at the level of right hemiabdomen.

AC: Rhythmic and regular without murmurs or rods. AR: MVC. No pathologic noise. Abdomen: tenderness at the level of right flank, without defense or signs of peritoneal irritation. Slightly positive right PPR.

COMPLEMENTARY TESTS

-          Rx of abdomen: no pictures of lithiasis in the projection made.

-          Rx thorax: normal ICT without images of pneumothorax or pneumonia.

-          Analytics: parameters within normal limits except up to 130 CRP elevation.

-          Analysis of urine: normal.

 

EVOLUTION

The patient is kept in the viewing area in order to control the pain with medication and the possibility of performing Imaging tests in case of no improvement of the clinical picture. Since our first diagnostic suspicion is renal colic not complicated, it may be necessary to the realization of an echo of abdomen in case of not achieve pain control.

After administration of dexketoprofen + tramadol + diazepam IV continuous patient with pain and fever of 39 °, performing abdominal reassessment appears: pain mainly locates it at the level of the iliac Fossa right, presenting localized defense and signs of peritoneal irritation.

Face us the question of if we are actually to a renal colic or a picture of appendicitis evolved, deciding the realization of abdominal CT scan: acute diverticulitis at sigma with adjacent Phlegmonous area associated with pneumoperitoneum. Minimum amount of liquid in FID. Features normal cecal Appendix.

CONCLUSIONS

The location of pain level right hemiabdomen, absence of fever, and lift only the PCR as analytical result was completely against the diagnosis made later with the abdominal CT scan. It is the persistence of pain despite the analgesic treatment as well as the emergence of fever which leads us to re-evaluate the abdomen and request the test image that was conclusive for the further development of the pathology. The patient entered in the service of general surgery where after 48 hours of intravenous antibiotic treatment was surgical intervention by absence of good evolution. Resection of segment affected with anastomosis in the same Act by laparoscopy, presented the patient after that good evolution, was being discharged within 7 days of carried out intervention.


Jorge PALACIOS CASTILLO, Pilar VALVERDE VALLEJO, David NÚÑEZ CASTILLO (SPAIN, Spain)
08:30 - 17:40 #11087 - White blood cells level in Cerebrospinal Fluid as a predictor of viral etiology in aseptic meningitis.
White blood cells level in Cerebrospinal Fluid as a predictor of viral etiology in aseptic meningitis.

BACKGROUND

Meningitis is defined as an increase of white blood cells (WBC) in Cerebrospinal Fluid (CSF), which may underlie infectious or no infectious disease. Aseptic Meningitis is defined as no bacterial infection in CSF and could be caused by a viral infection, meningeal not infectious reaction, inflammatory process or other. Most frequent serological tests are not done during the admission in emergency department. Symptoms and neurological examination make the difference between meningitis and meningoencephalitis (in these cases should exist some neurological deficit). Antiviral treatment should be administrated as soon as possible, futhermore if the symptoms are unclear.

OBJECTIVES

Assessment of the level of WBC in cerebrospinal fluid (CSF) as a predictor of positive outcome of viral etiology in patients with aseptic meningitis.

MATERIAL AND METHODS

An Observational and analytical study was performed. Inclusion Criteria were defined as patients diagnosed with aseptic meningitis between 2014 and 2016 admitted in the emergency room and neurological services of Virgen de la Victoria Universitary Hospital. Demographics data were collected, level of WBC in CSF and results of  Polymerase Chain Reaction (PCR) of CSF (Herpes Simplex Virus 1 and 2, Varicella Zoster and Enterovirus). Data were analyzed with SPSS.

RESULTS

55 patients meeted criteria. Blood test, Chest X-ray, electrocardiogram, Brain CT scan  were performed with normal results in all patients. Lumbar punture and CSF test and cultures were negative o non sugestive of bacterial infection. Serology and PCR blood test was also negative to systemic viral infection in all patients. Viral PCR in CSF was positive in 10 patients, with mean of 452±348 leukocytes/mm3. Viral PCR in CSF was negative in 45 patients, with mean of 150±157 leukocytes/mm3.  (UMW, p= 0.016). ROC curve for WBC and positivity of the PCR was performed for viral agents, with the Area under the curve of 0.746 (p= 0.016) Cut-off  was calculated in 185 leukocytes/mm3, obtaining maximum values of sensitivity = 0,8 and specificity = 0,73..

CONCLUSION

The level of WBC in CSF could be useful to predict the positivity of the viral PCR in patients with aseptic meningitis and may challenge the decision to administer intravenous antivirals.

 


Enrique CARO-VÁZQUEZ (MALAGA, Spain), Alejandro GALLARDO-TUR, Blanca SÁNCHEZ MESA, Eduardo ROSELL-VERGARA
08:30 - 17:40 #11454 - Why are important glucemic parameters during the hospitalization?
Why are important glucemic parameters during the hospitalization?

OBJETIVES: The objective of our study was to evaluate the influence of different parameters of glycemic control during the hospitalization, on the long term mortality.

MATERIAL AND METHODS: This was a longitudinal analytical retrospective cohort study. Patients discharged from Internal Medicine with some diagnosis related to diabetes were recruited for 8 months. The dependent variable was total mortality. Patients were followed from discharge until December 31, 2015. Clinical, analytical and glycemic control variables (baseline glycemia, HbA1c, blood glucose values during admission, and hypoglycemia) were collected. The glycemic variability was expressed by the coefficient of variation (CV). Determination of the predictive factors of mortality was performed using Cox uni and multivariate regression.

RESULTS: 276 patients were included (52.9% male). The mean age ± SD was 77.6 ± 10.2 years. The follow-up duration was 2.9 (SD 2.1) years and during the same died 162 (58.7%) patients. Of these, 71 (25.7% of the total sample) died due to cardiovascular causes. In the multivariate analysis, independent predictors of mortality were age (χ2 = 22.5, HR = 1.055, 95% CI 1.031-1.081, p <0.001), CV ≥ 0.30 (χ2 = 15.1, HR = 2 , 95% CI 1.42-2.95, p <0.001), a history of heart disease (χ2 = 10.5, HR = 1.85, 95% CI 1.27-2.70, p = 0.001 ), glomerular filtration (χ2 = 8.1, HRFG <30 = 1.30, 95% CI 1-2, p = 0.045), antecedent of neurological disease (χ2 = 5.71, HR = 1.61; 95% CI 1.10-2.36, p = 0.017) and the initial O2 saturation (χ2 = 5.44, HR = 0.96, 95% CI 0.94-0.99, p = 0.02 ).

CONCLUSION: Our study concludes that measures of glycemic control during hospitalization provide relevant prognostic information on long-term mortality.


Marta JORDÁN DOMINGO, Daniel SÁENZ ABAD (ZARAGOZA, Spain), Jose Antonio GIMENO ORNA, Carmen LAHOZA PÉREZ, Ana AGUDO TABUENCA, Ana ILUNDAIN GONZÁLEZ
08:30 - 17:40 #11604 - Why catheter ablation is not the final step in paroxysmal supraventricular tachycardia?
Why catheter ablation is not the final step in paroxysmal supraventricular tachycardia?

Background:Paroxysmal supraventricular tachycardia (PSVT) is defined as an abnormal, rapid heart rate, originating above the ventricles.The episodes can last from a few minutes up to several hours and most people aren’t in need of long-term treatment due to the fact that medication and procedures,that may be necessary only when the episode occurs,but they don’t prevent the new episodes.The recomandations are radiofrequency ablation or pacing.

Methods:An analytical, retrospective study of 280 cases of PSVT ranging between the 01.01.2015 and the 31.12.2016, based on statistical data from the Clinical Emergency County Hospital of Sibiu.We divided them in two groups. The first comprises patients admitted to the ER for more than two times, while the second features patients accusing just one episode of PSVT.

Results: There are 29 patients in the first sample,representing 51% from the lot (143 cases of PSVT from the total of 280).The patients’ average age in this group is 58,ranging from 36 to 83 year-olds.Besides PSVT,the patients associated pathologies as follows:cardiac (65.5%-high blood pressure,ischemic heart disease,chronic pulmonary heart disease,mitral valve prolapse),other arrhythmias and modifications on the ECG(31.3%-AFib,sinus tachycardia,LBBB,WPW), endocrine disorders (17.24%-5 patients with hypothyroidism),respiratory(13.29%-chronic obstructive lung disease,bronchopneumonia,chronic bronchitis)and metabolic(3.4%-type II diabetes).Out of the 143 emergency cases, only 25 were admitted to the Department of Cardiology for further inquiries(17.48%).

In the second lot there are 137 patients, having presented to the emergency department just once.They represent 49% of the total number of cases (280). The patient's average age in this group is 59,ranging between 24 and 85.Besides PSVT,the patients were known with the following pathologies:cardiac(31.38%-high blood pressure,ischemic heart disease,acute pulmonary edema,mitral valve prolapse,aortocoronary bypass,Tetralogy of Fallot), other arrhythmias and modifications on the ECG (7.29%-AFib, left bundle branch block,right bundle branch block,WPW),respiratory disorders(7.29%), metabolic (5.1% - type II diabetes,hyperglycemia), endocrine disorders (1.45%-2 patients with hypothyroidism).Out of the total of 137 cases, 68 were admitted to the Department of Cardiology for further inquiries (49.63%).

Discussion:  

This study reveals that many of the patients presenting to the Emergency Department, for either primary or recurrent PSVT episodes, have chosen not to go for further inquiries, after conversion to sinus rhythm.This is especially related to the first lot of patients. Furthermore,a significant number of cases were associating hypothyroidism. In terms of age, there is a slight difference between the average age of the cases presented in literature and the data in our study, the latter averaging higher.Is age an impediment or the absence of an centre specialized on electrophysiology and catheter ablation?


Petruta-Ioana CIOROGARIU, Constantin-Cosmin PITURLEA (Sibiu, Romania), Victoria ARDELEANU, Gabriela Diana DENDRINOS, Sorin IFRIM, Iris MURESAN, Irina PRISACARIU, Constanta STOICA
08:30 - 17:40 #11045 - Why has the colour of the urine changed?
Why has the colour of the urine changed?

CASE REPORT: A 81-years-old woman with antecedent of hypertension, vascular type dementia, diabetes mellitus type 2 and with a history of long-term indwelling urinary catheter. She is presented to the Emergency Department (ED) because of 3-days history of purple urine in the urine tube and urine bag, with any other symptomatology.  On the admission, the woman is hemodynamically stable and without any alarm data in the exploration, except on a discrete dehydration and purple urine in the urine tube and urine bag.

DIFFERENTIAL DIAGNOSIS: Hematuria due to urinary tract infection (UTI), renal stone, neoplastic process, porphyria, urine discolouration secondary to medication (rifampicin, ibuprofen, phenytoin, phenazopyridine, propofol, L-dopa).

EVOLUTION: Urine examination showed the presence of bacteriuria and leukocyturia, so we requested urine culture and started empiric Cefuroxime (500mg / 12h for 7 days). The urine culture was reviewed in Primary Care confirming isolation of Proteus mirabilis sensitive to Cefuroxime and evidencing at that time persistence of purpuric staining of the urine tube with emission of urine with normal aspect (Figure 1). Replace the urine tube and drift at home.

FINAL DIAGNOSIS: Purple urine bag syndrome due to UTI by Proteus mirabilis.

DISCUSSION: Purple urine bag syndrome is a rare phenomenon (prevalence 8.3-8.8%), which occurs mainly in the elderly female population who have remained on a urinary catheter for a long time. Other risk factors include: alkaline urine (the most common cause is by UTI), chronic constipation, and a diet rich in tryptophan. Pathogenesis is associated with tryptophan`s metabolism as intestinal bacteria metabolise tryptophan in food to indole and later convert it to indican by the liver. Indican, in turn, is excreted and broken down in the urine into indirubin (red) and indigo (blue) in an alkaline environment by sulfatase or phosphatase-producing bacteria, such as Providencia stuartii, Providencia rettgeri, Proteus mirabilis, Klebsiella pneumoniae and Escherichia coli (Figure 2). These metabolites then concentrate in the plastic tubing and the catheter producing an intense purple colour, giving rise to the purple urine bag syndrome. This syndrome is benign and is associated with poor hygiene of the catheter along with UTI. Normally the colour of the urine is normalized with the replacement of the probe without being obligatory the antibiotic treatment in the absence of data of infection.


Marta JORDÁN DOMINGO, Daniel SÁENZ ABAD (ZARAGOZA, Spain), Carmen LAHOZA PÉREZ, Cristina BAQUER SAHÚN, Teresa ESCOLAR MARTÍNEZ-BERGANZA
08:30 - 17:40 #11802 - Why is this strong abdominal pain?
Why is this strong abdominal pain?

Reason of consultation: Abdominal pain.

Clinic history: A 39 year old man comes to emergency service for abdominal pain located in iliac and hypogastric graves of a 5 days of evolution. At first it was of low intensity and not continuous but during the following days it increased in intensity until it became continuous. In addition, the patient presents slight discomfort in the urinary tract without increased urinary frequency. Without fever or other associated symptoms.

Phsysical exploration: Constans vitals: 97/72, 91 beats pm, T: 36ºC, 12 breaths pm. GGC, conscious, oriented. Cardiopulmonary auscultation: anodine. Abdomen: A little distended, painful with predominance in hypogastric, tympanic, noises present. No masses or megalias. Negative percussion fist. Defended abdomen, looks like acute abdomen.

Diagnostic trial: In the presence of ascites of debut and acute renal failure of prerrenal origin with asscociated methabolic acidosis, it was decided enter into Internal Medicine. Intensive chemotherapy, strict monitoring, bladder catheterization and diuresis control are initiated. A diagnostic paracentesis is also performed. Acute infection is ruled out. During the admission CT abdomen and abdominal echo-doppler was negative, bladder catheter is removed but after 12 hours the patient suffer a deterioration of seric creatinine and ascites. Without liver disease, and the presence of urea and creatinine in the ascitic fluid, we suspect the existence of a communication between the urinary tract and the peritoneum. Then it is done interconsultation to urology, who request a cystogram and urinary tract CT scan that confirms the presence of a microperforation in the bladder.

Conclusions: Ascitic syndrome is a common pathology in the emergency room. Most cases are due to cirrhosis of enolic origin. In absence of cirrhosis, the most frequent causes are cardiac insufficiency, Budd Chiari syndrome, portal thrombosis, neoplasias, tuberculosis, inflammatory diseases (vasculitis, amyloidosis, lupus). The diagnosis Requires paracentesis to rule out SBP and the sero-cystic albumin gradient in order to know whether the fluid is portal-hypotension or not. When we have ruled out a liver disease we must remember other causes less frequent of ascites such as bladder rupture that can be traumatic, secondary to abdominal or pelvic surgery or spontaneous.The clinic varies from an acute abdomen to acute renal failure.

In this case, the formation of a bladder fistula where the urine passes from bladder to peritoneum produces what is known as uroperitoneum, and subsequent reabsorption of creatinine from the peritoneum to the blood producing high levels of creatinine. Therefore, the drainage of the ascitic fluid and the bladder catheterization rapidly improve the creatinine levels.

Uroperitoneum is a medical emergency. It is a diagnosis of exclusion when rule out other causes like liver disease. The presence of palpable bladder or urination spontaneous  not exclude it.


Ignacio GONZÁLEZ SUÁREZ (LAS PALMAS, Spain), Bárbara MARTÍN GINER
08:30 - 17:40 #11216 - Women particularities in chronic obstructive pulmonary disease exacerbations.
Women particularities in chronic obstructive pulmonary disease exacerbations.

Introduction

Approximately 20% of the smoking population worldwide are women. The chronic obstructive pulmonary disease (COPD) prevalence and the frequency of deaths due to COPD in women is increasing. Few studies describe whether there is gender-associated differences in COPD exacerbations patients.

 

Aim of the study

Describe women particularities in COPD exacerbations patients admitted to the emergency department (ED).

 

Methods

Prospective observational study over a period of four months. Inclusion of adult patients admitted to the ED for COPD exacerbations. Comparison of demographic, habits, comorbidities, quality of life (COPD Assessment Test (CAT)), clinical and biological characteristics and treatment in men and women. 

 

Results

Inclusion of 198 patients. Sex-ratio = 3.95 (men n=158 (80%)). Overall mean age 67 ± 12 years. Female patients were younger (63±13 vs 67±12; p=0.035) and less active smokers n(%) 14(35) vs 123(78); p<0.001. They were more exposed to wood smoke n(%) (16(40) vs 5(3); p<0.001). Men were less affected in daily life (CAT>10 n(%): 112(71) vs 33(82) but with no significant difference. Comorbidities men vs women n(%): hypertension 25(16) vs 14(35); p=0.01 and diabetes 19(12) vs 14(35); p=0.001. Oxygen saturation at room air were lower in women (%) (90±9 vs 93±6; p=0,08). Non-invasive ventilation was used in 30% in women and in only 16% of men (p=0.023). Two women were admitted to the intensive care units for mechanical ventilation (5%) and only 1% of patients in male group.

 

Conclusions

Women with COPD exacerbations are younger, exposed to other particles than tobacco and have more comorbidities than men. Rapid initial evaluation is required since exacerbations seem to be more severe in women.   

  


Ines CHERMITI, Soumaya MAHDHAOUI (tunis, Tunisia), Hanène GHAZALI, Manel KALLEL, Morsi ELLOUZ, Mahbouba CHKIR, Saoussen CHIBOUB, Sami SOUISSI
08:30 - 17:40 #11136 - Would tranexamic acid be useful for an isolated femoral fracture?
Would tranexamic acid be useful for an isolated femoral fracture?

Introduction: The bleeding caused by isolated femoral shaft fractures is estimated (in 1992) to be an average of 1300ml ie 25% of the blood mass1. No other study has referred to it since. The administration of tranexamic acid (Exacyl) might decrease bleeding and the need for transfusion for this kind of fracture. The objective of our study was to assess the loss of blood, the fall of haemoglobin rate, the rate of transfusion related and the use of Exacyl related to this kind of fracture.

 

Materials and methods: A multicenter retrospective observational study took place from January 1st 2015 to November 20th 2016. Approval was obtained from the local Ethics Committee. Inclusion criteria: adult victim of isolated femoral shaft fractures. Exclusion criteria: femoral shaft fracture on prosthesis, on pregnant women or associated with other hemorrhagic lesions. Data collected from hospital medical records: age, gender, hemoglobin rate respectively upon arrival at the hospital H0, in post-operative, on 3rd and 5th day (D) of hospitalization, pre-operative blood loss, pre-surgery delay, type and duration of the surgery, transfusion pre or post-operative, administration of iron or tranexamic acid, post-operative complications.

 

Results:  66 patients were included from 3 hospitals, 38 were men, average age of 45 + 28 years. 26% had benefitted from prehospital traction. The median rate of hemoglobin was 13.1 g/dl IQR [12.2-14.3] on admission, 10.3 IQR [9.6-11.3] post-operative, 9.8 IQR [8.8-10.7] at D3, and 9.4 IQR [8.7-10.7] at D 5. The average loss of hemoglobin was 2.6 +1.6 g/dl between H0 and post-operative, 3.2+ 2.1g/dl between H0 and D3, 3.3+2.2 g/dl between H0 and D5. Tranexamic acid was administered pre-operatively to 44% (29/66) of patients; 70% of patients lost between 50-300 ml, 23% between 300 -500 ml and 7% more than 500 ml; 39% of the patients received transfusions of 2 red blood cells on average. 9 patients received iron administration 3 of whom were transfused. The patients operated on between 6 - 12 hours after their arrival; the median duration of intervention was 120 minutes [83-138]. No thromboembolic complications were observed. In bivariate analysis, the decrease in hemoglobin was not correlated to the rate of transfusion, the rate of administration of tranexamic acid, the type of surgical intervention or its duration, or to the time delay before operation.

 

Discussion:  The isolated femoral shaft fractures were responsible for the loss of an average 3.3g/dl of hemoglobin at D5 and the transfusion of a third of the patients. The estimated blood loss is less than that found in 1992 but the transfusion rate is higher. Almost half of the patients received Exacyl, which confirms the interest of the subject. The study continues in other centers. 

 


Olga MAURIN (Marseille), Antoine LAMBLIN, Bertrand PRUNET, Daniel JOST, Julie TRICHEREAU, Emmanuel HORNEZ, Clément DERKENNE, Stéphane TRAVERS, Jean-Pierre TOURTIER
08:30 - 17:40 #11776 - Wound botulism in Italy (1979-2016).
Wound botulism in Italy (1979-2016).

Background. Wound botulism (WB) occurs mainly in traumatic wounds and in injecting drug users as the consequence of in situ growing and toxinogenesis of Clostridium botulinum spores. The clinical syndrome is indistinguishable from that of food-borne botulism except for the absence of gastrointestinal symptoms. Fever can be present. Although this form of botulism was firstly recognised in 1950, it remains the botulism manifestation mainly underdiagnosed and rare. An improvement in physician’s awareness is essential for an early diagnosis and prompt therapeutic measures. Objective. To evaluate the prevalence of WB in Italy and to evaluate the frequency of the signs and symptoms in WB.  Case series. In Italy, the first case of WB was recognised in 1976. From 1976 to 2016, a total of eight cases were reported to the national register. Except for one (occurred in a drug user), all cases were due to traumatic injuries. All patients were adults, only one female. Neurological symptoms appeared in average 10.3 days after the injury. Ptosis, mydriasis, diplopia, and dysphagia were reported. Three patients presented constipation and respiratory failure, two were fatal. Fever appeared in 2 cases. As therapeutic measures antibiotics were administered to 6 patients, while botulinum antitoxin to 5. Hyperbaric oxygen treatment was applied to two injuries. All cases were laboratory confirmed through the detection of botulinum toxins in serum or by the isolation of Clostridium botulinum in the infected wound. Six of the 7 cases were due to type B toxin. Conclusion. In Italy WB is mainly underdiagnosed because its rarity and the difficulties in the formulation of clinical suspicion. WB should be considered in patients presenting with typical symmetrical descending flaccid paralysis when epidemiological investigation suggests that foodborne botulism is unlikely and where there is history of injecting drugs (skin popping). The lack of clinical suspicion is probably the main reason for which in Italy only a case occurred in a drug user was recognised. In fact, in other Countries (e.g. USA, United Kingdom) the high amount of WB are due to the consumption of contaminated drug unlike by the traumatic injuries. Another aspect is that the onset of symptoms is gradual, subtle and can occur during post-operative phase in surgical ward (e.g. orthopaedics). A common error is the correlation of typical neurological symptomatology of botulism only to a history of consumption canned food and not to traumatic injuries or wounds.


Davide LONATI (PAVIA, Italy), Bruna AURICCHIO, Marta CREVANI, Azzurra SCHICCHI, Fabrizio ANNIBALLI, Sarah VECCHIO, Carlo Alessandro LOCATELLI
08:30 - 17:40 #11260 - «Investigate the factors affecting the efficient and effective operation of the Emergency department: a systematic Review».
«Investigate the factors affecting the efficient and effective operation of the Emergency department: a systematic Review».

Abstract

Background: A properly organized A&E Department must provide a high quality emergency care and contribute significantly to limiting mortality and morbidity.  The aim of this literature review was to investigate- the factors affecting the efficient and effective services of A&E department.

Methods: This is a systematic review of all research articles looking into the factors affecting the efficient and effective services of the A&E department. The literature review was performed between October and November, 2015 in the databases PubMed, Cochrane Library, Wiley online library and Google scholar. This systematic review is concered of studies that have taken place over the last 15 years and criteria for inclusion of the studies was the clear correlation of the studies on the factors affecting the operation of the A&E department.  furthermore, publications are in English or Greek.

Results: Out of the 116 published articles detected 19 of them met the inclusion criteria in this review and are mostly cross-sectional quantitative surveys. Through the studies it appeares that the main factors that seem to affect the efficient operation of the A&E, include the continued population aging, the economic crisis, globalization, the poor health systems, and inadequate primary health care systems internationally

Discussions: The scientific community acknowledges the vital importance of proper functioning and use of A&E department, both for patients and for a country’s health system, engaged in an ongoing investigation of this matter, in order for the proper organizing and functioning of A&E department, but especially on providing quality emergency care to the patients. 


Andri EFSTATHIOU (Limassol, Cyprus), Mikaella SYMEOU, Eleni JELASTOPULU, Dafni KAITELIDOU, George CHARALAMPOUS

"Sunday 24 September"

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PC7
08:30 - 12:30

Airway Workshop for inner-clinical Emergency Medicine

Pre-Course Directors: Christian HOHENSTEIN (PHYSICIAN) (Pre-Course Director, BAD BERKA, Germany), Sabine MERZ (senior consultant) (Pre-Course Director, Villingen-Schwenningen, Germany)
TRACK F KOKALI
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PC1b
09:00 - 13:30

Pre-Course Ultrasound Advanced

MC-2
13:00

"Sunday 24 September"

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A11
13:00 - 14:30

Trauma (Cutting Edge)

Moderators: Katrin HRUSKA (Emergency Physician) (Stockholm, Sweden), Pr Suzanne MASON (Professor of Emergency Medicine) (Sheffield, United Kingdom)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
13:00 - 14:30 Paediatric concussion - recent updates. Silvia BRESSAN (Moderator) (Speaker, Padova, Italy)
13:00 - 14:30 Transcranial doppler in traumatic brain injury : what's news? Karim TAZAROURTE (Chef de service) (Speaker, Lyon, France)
13:00 - 14:30 Top 10 news on paediatric trauma. Ross FISHER (Consultant Paediatric Surgeon) (Speaker, Sheffield)
Trianti Hall

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B11
13:00 - 14:30

Education (How To)
How to build up a local training program? Podium discussion

Moderators: Christoph DODT (Head of the Department) (München, Germany), Riccardo LETO (Emergency physician) (Genk, Belgium), Nikolas SBYRAKIS (Consultant Emergency Physician) (Heraklion, Greece)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
13:00 - 14:30 The Odyssey of a Speciality - Arriving at last to Ithaka? Helen ASKITOPOULOU (Chair Ethics Committee) (Speaker, Heraklion, Greece)
13:00 - 14:30 The Standardized Training for Emergency Medicine Residency in China. Jie WEI (Director) (Speaker, Wuhan,China, China)
13:00 - 14:30 Development of emergency medicine training in USA: Who, why, how and what? Judith TINTINALLI (Professor) (Speaker, Chapel Hill NC, USA)
13:00 - 14:30 Panel Discussion. Eric DRYVER (Consultant) (Speaker, Lund, Sweden), Ruth BROWN (Speaker) (Speaker, London), Christoph DODT (Head of the Department) (Speaker, München, Germany), Judith TINTINALLI (Professor) (Speaker, Chapel Hill NC, USA), Helen ASKITOPOULOU (Chair Ethics Committee) (Speaker, Heraklion, Greece), Jie WEI (Director) (Speaker, Wuhan,China, China)
Mitropoulos

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C11
13:00 - 14:30

Pulmonary (Game Changers)

Moderators: Panos AGOURIDAKIS (IRAKLION, Greece), Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Besançon, France)
Coordinator: Nikolas SBYRAKIS (Coordinator, Heraklion, Greece)
13:00 - 14:30 Diaphragmatic ultrasound in COPD exacerbation. Gianmaria CAMMAROTA (MD, PhD) (Speaker, Novara, Italy)
13:00 - 14:30 Case based discussion: NIV in the Emergency Department - When and how? Panos AGOURIDAKIS (Speaker, IRAKLION, Greece), Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Speaker, Besançon, France), Roberto COSENTINI (Head of Emergency Medicine) (Speaker, BERGAMO, Italy)
Banqueting Hall

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D11
13:00 - 14:30

FOAM in Europe
YEMD Session

Moderators: Martin FANDLER (Consultant) (Bamberg, Germany, Germany), Laura HOWARD (United Kingdom)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
13:00 - 14:30 acilci.net - how to build a non-english FOAM site. Haldun AKOGLU (Faculty Member) (Speaker, Istanbul, Turkey)
13:00 - 14:30 FOAM in germany, from zero to hero? New concepts in emergency medicine training. Martin FANDLER (Consultant) (Speaker, Bamberg, Germany, Germany)
13:00 - 14:30 #FOAMed and accountability - beyond traditional peer review. Laura HOWARD (Speaker, United Kingdom)
Skalkotas

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F11
13:00 - 14:30

Free Papers Session 1

Moderators: Mohammad Ashraf BUTT (Consultant in Emergency Medicine) (Cavan, Ireland), Anna SPITERI (Consultant) (Malta, Malta)
13:00 - 14:30 #10829 - OP001 Management of non-vital polytrauma patients in the Emergency Department: A retrospective study.
OP001 Management of non-vital polytrauma patients in the Emergency Department: A retrospective study.

Introduction:

Severe trauma remains a major issue for public healthcare worldwide. Management of these polytrauma patients is mostly performed in intensive care units (ICU) that provide mutlidisciplinary care. The radiological evaluation is a vital part of their management and is essentialy based on performing a whole-body computed tomography (WBCT). However, less attention has been paid to the management of non-vital polytrauma patients in the Emergency Departments (ED). The aim of the study was firstly to evaluate the management of non-vital polytrauma patients who had a WBCT in our ED. We also performed this study to find predicting factors of severity at hospital admission.

Methods:

We present here a retrospective and monocentric study. We reviewed the chart of all patients who had a WBCT (for trauma) in 2014. We collected epidemiological, clinical and biological parameters and all therapeutic measures during the ED stay. A long-term survival follow-up was also performed. All patients directly admitted to the ICU were excluded.

Results:

A total of 210 patients were included for statistical analysis and 64% (CI95% : [57.8-70.8]) of them had one or more lesion(s) in the WBCT (36% normal WBCT). The mean ISS score was 10.1±8.8. 42 patients (20% ; CI95%: [14.6-25.4]) underwent urgent surgical procedures or were admitted to the ICU. We have defined these patients (n=42) as severely injured trauma patients. The mean ISS score for these patients was 16,1±10.8 compared to others 8,5±7.5 in the remaining cohort (p<0.0001). The mortality rate predicted by the TRISS model was 3,1% compared to 1,5% in the whole cohort (p<0.0001). The average length of stay in the ED was 5,4±2.9  hours for the severely injured trauma patients versus 7,2±4.6  hours for the other patients of the study (p=0.003) and the average lenght of stay was 16,2±18.9 days for the severely injured group versus 3,1±6.4 days for the non-severely injured patients (p<0.0001). In multivariate analysis, heart rate (>100/min) and Vittel score (³2 criterias) were related to the probability of belonging to the severely injured trauma group (p=0.03). The 24-hour mortality rate was 0.5% in the ED and the 30-day mortality rate was 1.5%.

Conclusion:

The development of a specific network in the ED hosting non-vital but severly injured polytraumas remains crucial. The primary goal of this future network will be to meet technical and time requirements and establish new in-hospital triage algorithms based on clinical variables (such as heart rate), in order to detect these patients at an early stage and offer them priority care in our overcrowded EDs.


Luc BILGER (Strasbourg), Pierrick LE BORGNE, Florent BAICRY, Sarah UGÉ, Sophie COURAUD, Philippe KAUFFMANN, Etienne QUOIRIN, Pascal BILBAULT
13:00 - 14:30 #10838 - OP002 Predictive factors of intracranial bleeding after head trauma in patients under antiplatelet therapy admitted to emergency unit.
OP002 Predictive factors of intracranial bleeding after head trauma in patients under antiplatelet therapy admitted to emergency unit.

Introduction. Traumatic brain injury (TBI) is very common in emergency department. Most of them are the results of mild head injury defined by a Glasgow coma scale score greater or equal to 13. In case of head trauma under antiplatelet agent, guidelines of the French Society of Emergency Medicine required to perform a CT scan to detect brain lesions. In this indication, 90% of CT scan are normal. The utility of CT is still debate given controversial and scarce number of studies.

Methods. We used the RATED registry (Registry of patient with antithrombotic agents admitted to an Emergency Department, NCT02706080) to assess factors of cerebral bleeding related to antiplatelet agent after head trauma. RATED is a monocentric, ongoing (from January 2014), observational registry of consecutive patients under antithrombotic drugs admitted to an emergency department. For this study, only patients under antiplatelet drugs at admission, with a head trauma who benefit a CT scan, were considered. Those under anticoagulants drugs were excluded.

Results. From January 2014 to December 2015, 993 patients under antiplatelet agent were recruited. Of these, 293 (29.5%) underwent a CT scan for trauma brain injury. Intracranial bleeding was found in 26 patients (8.9%). After multivariate analysis, these patients were more likely to have a history of severe hemorrhage (OR = 8.47, 95%CI: 1.56-45.82), a dual antiplatelet therapy (OR = 6.46, 95%CI:1.46-28.44), headache or vomiting (OR = 4.27, 95%CI: 1.44-2.60) and less frequently a glasgow coma scale of 15 (OR = 0.11, 95%CI: 0.03-0.35) than those without intracranial bleeding. The predictive model derived from these variables had a specificity of 98.9% and a Negative predictive value of 92%. The area under curves of the ROC curve was 0.85 (95%CI: 0.77-0.93).

Conclusions. Our study showed that the absence of a history of severe hemorrhage, dual antiplatelet therapy, headache or vomiting, and normal Glasgow coma scale score seems to predict a normal CT scan after trauma brain injury under antiplatelet. This founding need to be confirmed by prospective studies.


Farès MOUSTAFA (Clermont-Ferrand), Jean ROUBIN, Alain BARRES, Bruno PEREIRA, Jennifer SAINT-DENIS, Coralie SERRANO, Christophe PERRIER, Julien RACONNAT, Jeannot SCHMIDT
13:00 - 14:30 #10979 - OP003 Fall-related injuries in the aged.
OP003 Fall-related injuries in the aged.

Background

Falls constitute a significant challenge in health care, particularly in the oldest age groups. We aimed to investigate the incidence of fall-related injuries among the older Finns.

Materials and methods

In this retrospective population-based study, we registered all consecutive emergency admissions due to fall-related injuries in a high-volume emergency department (ED) during a 2-year study period (January 2015 to December 2016). The catchment area of the study hospital exceeds 1 million inhabitants in tertiary care services, and it provides both primary and tertiary care ED services for a population of 226,696 inhabitants (10,991 aged 80 years or more). Patients were eligible for this study if they were 80 years or older. Patient demographics and diagnoses were retrieved from hospital records. The key factor under analysis was the incidence of fall related injuries.

Results

During the study period, 2,951 patients (median age 87, range 80-104; 73 % females) had 3,802 emergency admissions due to fall-related injuries (2.2% of all ED visits and 11% of all visits in this age group). The incidence of these injuries increased from 49/1,000/year in inhabitants aged 80-89 years to 87/1,000/year among those aged ≥90 years (p<0.001). The risk was also higher among females (p<0.001), the incidence was 60/1,000/year among females and 45/1,000/year among males. Typical injuries caused by falls included, fractured femur (21%), intracranial injury (19%, with intra-cranial hemorrhage in 5% of patients), open head wound (15%) and forearm fracture (7%). The number of injurious falls of all ED visits varied from 253-358 from month to month, with no association with time of year. Recurrent falls were registered in 39% of patients (range 1-5 falls). When single fallers and recurrent fallers were compared, older age and female gender were not associated with higher risk of recurrences (p>0.05). In community-dwellers, most injuries (64%) occurred in domestic setting. Ten percent of all patients were admitted to hospital from nursing homes.

Conclusions

The observed incidence of fall-related injuries is lower than in earlier reports. Nevertheless, these incidents cause a significant burden to emergency services. While the risk of single falls increased with age and was also higher among females, these risk factors were not associated with higher risk of fall recurrences.


Saara SOUKOLA, Satu-Liisa PAUNIAHO, Esa JÄMSEN, Sally JÄRVELÄ, Tuuli LÖFGREN, Mika UKKONEN (Tampere, Finland)
13:00 - 14:30 #11629 - OP004 The role of bedside US in detection of early expanding traumatic pneumothorax in-patient who require positive pressure ventilation.
OP004 The role of bedside US in detection of early expanding traumatic pneumothorax in-patient who require positive pressure ventilation.

 Introduction:

One of the most important factors for total morbidity and mortality in traumatized emergency patients is chest trauma; the complexity of injury in trauma patients makes it challenging to provide an optimal oxygenation while protecting the lung from further ventilator-induced injury to it. Ultrasound has a well-known established role in the diagnosis of a traumatic pneumothorax.

Case series: We are reported 46 patients with traumatic pneumothorax who require positive-pressure ventilation   recruited from Alexandria Main University Hospital Emergency Department who examined pre and post CT-Chest scanning by the same operator between November 2015 and September 2016.

Inclusion criteria: Any patient with either blunt or penetrating chest trauma regardless the age or gender who require positive-pressure ventilation.

Exclusion criteria: patients with open or tension pneumothorax.

The chest scanned (using the superficial probe 7.5 MHz type L7M-A of our CHISON device model ECO 2) at three lines and two views for each hemithorax as the following (1)anterior second through sixth intercostal spaces at the parasternal line, (2) anterior second through sixth intercostal spaces at the mid-clavicular line, (3) fourth through sixth intercostal spaces at the anterior axillary line,(4) fourth intercostal space at the mid-axillary line, (5) fourth intercostal space at the posterior axillary line, to assess for the presence of a sliding lung.

We analyzed 46 patients, 85% were men, with median age of 27 for the total number of patients. The results of ultrasound scanning of intubated patients’   pre CT scan in comparison to the result of ultrasound scanning after the CT scan of the chest to detect the behavior of traumatic pneumothorax. Six patient (13%) had expanding pneumothorax detected by CT chest and comforted by bedside US. One patient developed right tension pneumothorax after 6 hours, in which pre CT US scanning was Right minimal pneumothorax and Left minimal pneumothorax, post CT after 35 minute was Right mild pneumothorax and left minimal pneumothorax. Another patient developed massive left pneumothorax discovered accidental during CT abdomen, pre CT US scanning was Right mild pneumothorax and free left pneumothorax, post CT was Right mild pneumothorax and left minimal pneumothorax.                                                                                                                                                     

Conclusion: Bedside US lung could be used a predictive tool in detection of early expanding traumatic pneumothorax in-patient on positive-pressure ventilation.


Dr Muhammad ABDULHALEEM HAMADA (Egypt, United Kingdom), Sara Mohamed Kamal El-Din ELTAYEB
13:00 - 14:30 #11634 - OP005 Scand-Ankle – The effect of alcohol intervention regarding complications after acute ankle fracture surgery (RCT).
OP005 Scand-Ankle – The effect of alcohol intervention regarding complications after acute ankle fracture surgery (RCT).

M.D., PhD-student Egholm JWM1,2, PhD Pedersen B1,3, M.D. Oppedal K4, Professor M.D. Lauritzen JB5, M.D. Madsen BL6, Professor M.D. Tønnesen H1,3

1WHO-CC, Clin Health Promotion Centre, Bispebjerg-Frederiksberg Hospital, University of Copenhagen, Denmark; 2Orthopedic Dept, Hospital of Southern Jutland, University of Southern Denmark; 3Clin Health Promotion Centre, Dept Health Sciences, Lund University, Sweden; 4Alcohol and Drug Research Western Norway, Stavanger University Hospital, Norway; 5Dept Orthopaedic Surgery, Bispebjerg-Frederiksberg Hospital, University of Copenhagen, Denmark; 6Dept Orthopaedic Surgery, Hvidovre Hospital, University of Copenhagen, Denmark.

Introduction:

Patients with hazardous alcohol intake are overrepresented in emergency departments and surgical departments. In elective surgery, preoperative alcohol cessation interventions can reduce postoperative complications[1] but no studies have investigated the effect of alcohol cessation intervention at the time of surgery for acute fractures.

 

Purpose:

To evaluate the effect of the Gold Standard Programme for alcohol cessation intervention (GSP-A) for patients undergoing acute ankle fracture surgery regarding postoperative complications.

 

Methods

Our RCT design included a total number of 70 patients from Hvidovre and Bispebjerg Hospitals with an excessive intake of alcohol and an ankle fracture that required osteosynthesis. They were allocated to either standard care or a 6-weeks GSP-A aiming to complete alcohol abstinence peri- and postoperatively.

 

GPS-A involved a patient educating programme and weekly sessions at the orthopedic outpatient clinics. Furthermore, patients were provided with thiamine and B-vitamins, prophylaxis and treatment for alcohol withdrawal symptom and disulfiram to support abstinence.

 

Biochemical validation of alcohol intake was carried out. Follow-up took place after 6 weeks and 3, 6, 9 and 12 months.

 

The main outcomes were postoperative complications (requiring treatments), alcohol intake and cost-effectiveness.

 

Results:

In the GSP-A group 12 patients (34%) developed complications compared to 14 patients (42%) in the control group (p=1.0).

 

Interestingly, 14% in the control group versus 51 % in the in the GSP-A group had abstained completely from alcohol at 6 weeks follow up. (p=0.001).

 

Conclusion:

We found no statistically significant differences in the number of complications between the intervention and control group.

We are looking forward to evaluate the cost-effectiveness of the study to see if there is a difference between the two groups. Biochemical analysis is still ongoing.

However, the majority of the intervention group completely abstained from alcohol in the intervention period.

 

 

Contact information: julieweberegholm@gmail.com

 

 

 


[1] Tønnesen et al. Smoking and alcohol intervention before surgery: evidence for best practice. Br J Anaesth. 2009 Mar;102(3):297-306.

 


Julie Weber EGHOLM (Copenhagen, Denmark)
13:00 - 14:30 #11672 - OP006 Comparison of time to return to work for different injured body regions following moderate and severe trauma in Hong Kong.
OP006 Comparison of time to return to work for different injured body regions following moderate and severe trauma in Hong Kong.

Background

Head, neck, extremity, thorax and abdominal injuries are the main injury sites for trauma in Hong Kong. Return to work (RTW) status is an indicator of their outcome and an important element in their social reintegration. Besides physical recovery, RTW may be affected by the psychological characteristics of patients, available technologies that can assist their functional recovery and socioeconomic factors. Some of these are modifiable and may vary between injury sites.  The aim of this study was to compare the time to return to work (RTW) and time to reach Hong Kong norm of SF36 of patients who sustained moderate to severe injuries at these sites. This may help to identify the type of injury where research is most needed to bridge the gap between time to recovery and return to work.

Methods

This was a multicenter, prospective cohort study of patients entered into the trauma registry of the three regional trauma centres in Hong Kong. Patients were included if they were aged between 18 and 70, with an ISS³9 and were working or seeking employment before injury. Outcome measures included physical component summary (PCS) and mental component summary (MCS) scores in SF36 and their return to work status over 5 years. The Hong Kong norm for PCS is defined as >52.83 and that for MCS is >47.18.

Results

189 patients were recruited to the study from 1 January to 31 September 2010 (mean age 41.4 years; 80.4% male). 99 (52.4%) patients had head or neck injuries, 44 (23.3%) had extremity injuries, 39 (20.6%) had thoracic or abdominal injuries, and 7 (3.7%) had spinal or other body region injuries. 5-year mortality rate was highest in head injury patients (12/99, 12.1%, 95%CI 6.4-20.2%), followed by extremity injury (1/44, 2.3%, 95%CI 0.1-12.0%). There was no death in patients with injury in other parts of the body. For patients that are still alive at 5 year follow-up (n=87, 43 and 39 for head/neck, extremity and thorax/abdomen injuries respectively), Kaplan-Meier curves of time to RTW were different between the three principal injury sites (log-rank test p=0.041). Mean time to RTW for head/neck injury was 2.2 years (95%CI 1.6-2.8 years), 2.3 years (95%CI 1.5-3.1 years) for thoracic/abdominal injury and 3.6 years (95%CI 2.8-4.5 years) for extremity injury. However, Kaplan-Meier curves of time to reaching the Hong Kong normal PCS or MCS showed no significant difference between the three injury sites (log-rank test p=0.386 and 0.482 respectively; mean time to PCS>52.83 ranged from 3.3-4.0 years and mean time to MCS>47.18 ranged from 2.0-2.3 years).

Discussion

Among the factors that affect the RTW status besides health status, some of them are specific to extremity (limb) injuries. This may represent a specific group for targeted rehabilitation to shorten the time to RTW.

 

Funding

The study has been conducted with the support of the Health and Health Service Research Fund from Hong Kong government (HHSRF 07080261).


Dr Kevin Kei Ching HUNG (Hong Kong, Hong Kong), Yuk Ki LEUNG, Timothy H RAINER, Kai Yeung YUEN, Janice Hh YEUNG, Hiu F HO, Chak W KAM, Colin GRAHAM
13:00 - 14:30 #11790 - OP007 Is the use of collar in Whiplash Associated Disorders (WAD) more associated to a worse recover? A retrospective study.
OP007 Is the use of collar in Whiplash Associated Disorders (WAD) more associated to a worse recover? A retrospective study.

Background: whiplash Associated Disorders (WAD) are very frequent reasons for request of health care interventions in acute setting. They involve about 30-40% of people after a car accident, and they are a growing problem in terms of both health and insurance costs. The “gold standard” of WAD in acute management is not established and the application of cervical collar continues to represent a common practice, although it is known that it does not to improve the course of disease.

Aim: the goal of this study is to assess whether the use of cervical collar in patients with WAD is associated to a higher risk of readmission within 90 days from trauma and the likely onset of post-traumatic associated syndrome

Methods: we retrospectively evaluated all the patients observed in the Emergency Department (ED) of the University Hospital of Verona for WAD, according to the Quebec Task Force definition. We considered only the patients with isolated WAD within 48 hours from a car accident, excluding those with associated head trauma. At the ED evaluation time we registered for each patient: the demographic and clinical features; the time and mechanism of trauma; the grade of WAD and if the application of cervical collar was performed or not. Moreover, we excluded the patients in case of rx assessment of cervical spine fracture (WAD 4). We carried out a multivariate analysis to verify the impact of the cervical collar on the outcome adjusted for grade of WAD. Finally, we submitted our series of patients to propensity score matching, in order to reduce the bias of a retrospective study, and then we repeated the statistical analysis on the selected cohort of patients.       

Results: from January 2013 to December 2014 we observed 2156 patients with WAD (grade 0 to 3). In most of the cases (85.5% of the patients) a cervical collar was applied. An overall number of 162 patients (7.5%) had a readmission within 90 days from trauma and 154 (7.1%) out of them used a cervical collar (p = 0.001). Cervical immobilization resulted to be a significant risk factor for readmission both in univariate (OR 3.663, 95% IC 1.684-7.122) and in multivariate analysis (adjusted OR 3.561, 95% IC 1.255-7.349). After the propensity score matching we selected 482 patients equally divided (50% with and 50% without cervical collar). Even in the selected series readmission rate was higher in patients with cervical collar (10.4% vs 2.9%, p < 0.001). The risk was confirmed both in univariate (OR 3.869, 95% IC 1.640-9.127, p = 0.002) and in multivariate analysis (adjusted OR 3.878, 95% IC 1.643-9.153, p = 0.001).

Conclusion: the application of cervical collar in WAD appears to be an independent risk factor for the onset of post-traumatic associated syndrome. These results are not related with the grade of WAD and they have been confirmed even when propensity score matching was performed.


Giacomo ROSSETTINI, Gianni TURCATO, Massimo ZANNONI, Dr Antonio BONORA (VERONA, Italy), Alberto RIGATELLI, Giorgio RICCI
13:00 - 14:30 #11845 - OP008 Prognostic factors for severe blunt trauma patients according to chest injury severity. Analysis from the FIRST study.
OP008 Prognostic factors for severe blunt trauma patients according to chest injury severity. Analysis from the FIRST study.

INTRODUCTION: Severe blunt trauma is associated with a high risk of morbidity and mortality. The chest wall and vital organs inside the chest are commonly affected. The purpose of the present analysis was to determine whether the prognostic factors in patients with severe trauma were modified by the severity of the chest trauma.

METHODS: This is an ancillary analysis of the FIRST study, a multicenter cohort study on consecutive patients with severe blunt trauma requiring admission to intensive care units at university hospital trauma centers within the first 72 hours. The analysis was restricted to patients admitted directly to a university hospital trauma center. The main endpoint was the survival within the first 30 days after the trauma.

RESULTS: Of the 2,052 patients analyzed, 583 (28%) had a severe chest trauma (chest AIS > 3). The 30-day mortality was 22% in the chest AIS > 3 group and 17% in the chest AIS ≤ 3 group (p = 0.006). In bivariate analysis, only age and accident type comparing motorcycle/ bicycle crashes with motor vehicle crashes had a significant interaction term with chest trauma severity (p=0.003 and p=0.0015). In multivariate analysis, the interaction between age and severe chest trauma became non-significant (p= 0.12) after adjustment for the Glasgow Coma Scale (GCS) and/or head AIS whereas that between motorcycle/ bicycle crashes and severe chest trauma remained significant (p= 0.042) even after adjustment for GCS, heart rate, age, sex and head AIS. In the severe chest trauma group, motorcyclists/bicyclists had a higher mortality risk than did victims of motor vehicle crashes (SHR: 1.66; 95% CI, 1.08–2.55; p= 0.02), whereas in the non-severe chest trauma group, motorcyclists/bicyclists had the same mortality risk as victims of motor vehicle crashes (SHR: 0.97; 95% CI, 0.66–1.42; p= 0.87).

CONCLUSION:there is a surplus mortality risk among motorcyclists when they have severe chest trauma, contrary to the vehicle accident victims and pedestrians. This high-risk mortality group must be identified to establish preventive priorities and efficient management of existing injuries, in order to improve the outcome.


Riadh TFIFHA (Dijon), Abderrahmane BOURREDJEM, Claire BONITHON-KOPP, Marc FREYSZ
13:00 - 14:30 #11940 - OP009 Inhibition of potassium voltage-dependent channels and hydrogen disulfide production restores the blood pressure and improves the survival in anaphylactic shock in Wistar rat model.
OP009 Inhibition of potassium voltage-dependent channels and hydrogen disulfide production restores the blood pressure and improves the survival in anaphylactic shock in Wistar rat model.

Introduction:  Anaphylactic shock (AS) is a life-threatening condition in which blood circulation fails to meet oxygen demands of organs in the body. Restoring effective circulation is the major objective of treatment which can sometimes be resistant to conventional treatments available. We evaluated novel drugs targeting specific pharmacological pathways to define therapeutic alternatives or supplements to epinephrine. The role of potassium voltage-dependent channels (Kv) and hydrogen disulfide (H2S), a potent vasodilator, was not explored in AS.

Objectives: Our objective was to demonstrate that the inhibition of Kv with 4 aminopyridine (4-AP) alone or combined with the inhibition of the production of H2S with dl-propargylglycine (PEG) or betacyanoalanine (BCA) restores blood pressure and improves survival.

Methods: Rats were sensitized with ovalbumin (OVA, 1mg s.c), and AS was induced by i.v. injection of OVA (1mg) through jugular vein catheter. Experimental groups included NA=non-allergic rats (N=6); Controls=allergic rats (N=10); allergic rats treated with 4-AP (1 mg/kg) (N=10); epinephrine (EPI)=allergic rats treated with EPI (10 µg/kg) (N=10), allergic rats treated with PEG (N=10), allergic rats treated with BCA (N=10). Treatments were administered 1 minute after induction of AS. Mean arterial blood pressure (MAP), heart rate (HR) were measured through carotid artery catheter

Results: MAP, HR, and survival were measured for 60 minutes. MAP was normal in the NA group; severe hypotension and high mortality were observed in controls; normalization of MAP, HR, and increased survival were observed in 4-AP, DPG, BCA, 4-AP+DPG or BCA, and EPI groups. Survival time was: controls=22±3 min, EPI=59±1 min, 4-AP=60 min, DPG=49±5 min, BCA=44±7 min, 4-AP+DPG=58±2, 4-AP+BCA=60 min. All allergic 4-AP and 4-AP+BCA-treated rats survived after the induction of AS (p<0.05).

Conclusion: We demonstrated that the allergen-activation of Kv is a probably a new pathway involved in the vasodilation induce by AS in a rat model. It seems that H2S is a major mediator released during AS in endothelial and vascular smooth muscle cells and could play a role in the induction of AS. Inhibition of Kv alone or combined with the inhibition of H2S production improves significantly survival and restore blood pressure. 


Pr Abdelouahab BELLOU, Fayez Ebrahim ALSHAMSI (Al Ain, United Arab Emirates), Ibrahim ABDALLA, Suleiman ALHAMMADI, Dhanasekaran SUBRAMANIAN, Mohamed SHAFIULLAH, Elhadi ABURAWI, Abderrahim NEMMAR, Moufida ZERROUKI, Sirine BELLOU, Leila BELLOU, Seth ALPER, Elsadig KAZZAM
Kokkali
14:35

"Sunday 24 September"

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PH1 -S3
14:35 - 14:55

E-Poster Highlight Session 1 - Screen 3

14:35 - 14:40 #11367 - Errors in HEART score calculation for chest pain patients at the emergency department: frequency, circumstances and potential consequences.
Errors in HEART score calculation for chest pain patients at the emergency department: frequency, circumstances and potential consequences.

Background: The HEART score can accurately stratify the risk of major adverse cardiac events (MACE) in chest pain patients. We investigated the frequency, circumstances and potential consequences of errors in its calculation.

Methods: We performed a secondary analysis of a stepped wedge trial of chest pain patients presenting to nine Dutch emergency departments. We recalculated HEART scores for all patients by reevaluating the elements Age (A), Risk factors (R) and Troponin (T) and compared these new scores with those given by physicians in daily practice. We investigated which circumstances increased the probability of incorrect scoring and explored the potential consequences.

Results: The HEART score was incorrectly scored in 266 out of 1,752 patients (15.2%; 95% CI 13.5%-16.9%). Most errors occurred in the R (“Risk factors”) element (61%). Time of admission, and patient’s age or gender did not contribute to errors, but more errors were made in patients with higher scores. In 102 patients (5.8%, 95% CI 4.7%-6.9%) the incorrect HEART score resulted in incorrect risk categorization (too low or too high). Patients with an incorrectly calculated HEART score had a higher risk of MACE (odds ratio 1.85; 95% CI 1.37-2.50), which was largely related to more errors being made in patients with higher HEART scores.

Conclusion: Our results show that the HEART score was incorrectly calculated in 15% of patients, leading to inappropriate risk categorization in 5.8% which may have led to suboptimal clinical decision making and management. Actions should be taken to improve the score’s use in daily practice.


Marten RAS, Johannes REITSMA, Jacob SIX, Arno HOES, Judith POLDERVAART (Utrecht, The Netherlands)
14:40 - 14:45 #11679 - F.A.S.T.: Focus on Accelerating Sepsis Triage.
F.A.S.T.: Focus on Accelerating Sepsis Triage.

Background:
In Tuscany Triage System priority code is assigned by the triage nurse on the basis of symptoms and vital signs (BP, HR, SaO2, RR, T°). Overcrowding affect all the EDs with long times to medical evaluation. Septic patients may present with “normal” vital signs and aspecific symptoms receiving a low priority code. The challenge is to rapidly identify those that will develop sepsis and septic shock. Shock Index has been shown to be a strong predictor for these conditions. Lactate is proven to be useful to stratify prognosis in the Emergency Department and particularly among septic patients.

Methods:all patients with fever or history of fever in the previous 7 days were evaluated by symptoms and measurements of vital signs. Using Shock Index (SI = FC/PA) and lactate they will be stratified to Green priority (SI>0.7 and lactate<2 mmol/l), Yellow priority (SI>0,7 and 2<lactate<4 mmol/l) and Red priority (SI>0,7 and lactate>4 mmol/l. Lactate was obtained with i-Stat POC Abbott. We looked at the number of diagnosis of Sepsis, Severe Sepsis and Septic Shock obtained respect to the same period of the last year. We measured time to fluid administration, time to antibiotic administration, and time to diagnosis in 415 patients presenting in four different Emergency Departments (A,B,C,D – see in the results) from April, 1st 2016 to December, 31st 2016.

Results: overall data show median time from triage to fluid administration varying from 14 min in Center (B) to 60 min in Center (C). Median time to antibiotic administration varied from 42 min (BCenter) to 125 min (ACenter). Median time to diagnosis varied from 140 min in A Center to 260 min in the D Center. All Centers showed improvement in the number of sepsis diagnosis compared with same period of year 2015: +17,7%(A center),+42,6%(B center), +24,5%(C center), +68%(D center). The Center A showed an improvement in median time to fluid administration for patients with septic shock (55 min in 2015 to 5 min in 2016); and no difference in time to antibiotic administration in this subpopulation (55 min–2015 vs 60 min-2016). Patients with severe sepsis showed an improvement in time to fluid administration (60 min in 2015 vs 25 min 2016) and in time to antibiotic administration (122 min in 2015 vs 45 min 2016).

A- Livorno (1° level ED-70000 p/y)
B- Siena (University hospital-50000 p/y)
C- S. Maria Annunziata, Firenze (1° level ED-38000 p/y)
D- Cecina (Peripheral ED-30000 p/y)


Discussion:
The study was planned before the Sepsis-3 definition and measured the impact of a simplified triage on Sepsis pathway. If we use SIRS criteria (or even qSOFA criteria) a lot of patients will be recruited as potentially septic patients even if they were not. A simplified Triage taking into account SI and lactate levels can identify those patients at risk to develop Sepsis or Septic Shock and showed to be easy to apply even in small volume Centers. Data analysis is still ongoing so that we can offer further analysis at the Meeting


Alessio BERTINI (Pisa, Italy), Irene DI PACO, Germana RUGGIANO, Andrea CAMARRI, Paolo PENNATI, Gianfranco GIANNASI, Renzo CAMAJORI-TEDESCHINI
14:45 - 14:50 #11771 - Correlation between troponin level and magnitude of the ST depression in acute coronary syndrome.
Correlation between troponin level and magnitude of the ST depression in acute coronary syndrome.

Background:  Troponin is an independent prognostic factor that can identify patients with an increased likelihood of intracoronary thrombi. Because Troponin takes a finite time to appear, the electrocardiogram is a readily available tool for assessing these patients. The analysis of the magnitude of ST segment Depression (STD) in identified high-risk coronary patients is still not very well established. The aim of this study was to examine the relationship between the magnitude of STD and troponin values.

 Methods: Prospective observational study conducted over a period of 4 months (January-April 2016) in the emergency department.  We enrolled patients aged more than 18 years, presenting to the hospital alive with presumptive diagnosis of ACS and ST depression on the admission. Collection of epidemiological, clinical, therapeutic and biological parameters.

Results: sixty five patients were enrolled. The average age was 62 years with a sex ratio = 2.6. Cardiovascular risk factors were dominated by smoking (65%) followed by hypertension (50%), diabetes (34%) and coronary artery disease (34%). The median time of consultation was 12 hours. The analyses of the amplitude individualize 3 groups of patients: G1≤ 1mm = 29; G2 [1-2[= 26 andG3 ≥2 mm = 10. Troponin was positive in 51 patients (78%) of which 40 were positive to H6. Applying the Spearman correlation test, there was no correlation between the magnitude of ST segment depression and values of troponins (RHO =0.05; p = 0,69 in admission, RHO = 0.20; p=0.43 à H3).

Discussion: Although the presence of any ST-depression is an independent predictor factor in risk- stratifying patients with acute coronary syndrome, its quantitative analysis not improve identification of high risk patients

 


Nader BEN OTHMEN (Monastir, Tunisia), Hana HEDHLI, Sarra JOUINI, Mohamed KILANI, Ahmed SOUYEH, Abir WAHABI, Abderrahim ACHOURI, Chokri HAMOUDA
14:50 - 14:55 #11794 - COULD LABORAATORY PARAMETERS SUPPORT THE OUTCOME PREDICTION IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE?
COULD LABORAATORY PARAMETERS SUPPORT THE OUTCOME PREDICTION IN PATIENTS WITH ACUTE DECOMPENSATED HEART FAILURE?

Background

Acute decompensated heart failure (ADHF) is a severe clinical conditon charactirized by a rapid worsening of sign and symtoms of cardiac impairment and associated with high hospitalization rates and increased short-term mortality. Therefore the availability of reliable parameters to predict the outcome of patients with ADHF is a matter of great clinical relevance. A number of risk stratification models have been proposed by the combination of both clinical and laboratory parameters, but none of these has proved really helpful in accurately predicting short-term prognosis of ADHF patients.

 

Aim

To assess whether a set of laboratory parameters easily collected at the time of observation could help to predict the outcome of patients with ADHF.

 

Patients and Methods

In this retrospective study we enrolled all the patients observed for ADHF in the Emergency Department (ED) of the University Hospital of Verona from June 2013 to November 2015. Diagnosis of HF was consistent with ESC 2016 Guidelinesand patients were excluded in case of associated disease. A number of laboratory parameters, registered at the ED admission, were considered as categorical variables. The primary endpoint was the 30 and 90 days mortality. Categorical variables were compared with chi-square or Fisher's exact test and introduced in logistic regression model using backward stepwise selection. Multivariate model was then used to create a nomogram aimed to predict the mortality risk. The predictive performance of the nomogram was analyzed trough ROC curve analysis and AUC and further validated by means of bootstrap resampling. Finally Kaplan-Meier survival curves were constructed according to the different risk probabilities calculated by nomogram. Differences were compared with Log-Rank test with significance level p < 0.05.

 

Results

The study population consisted of 1031 patients. The overall 30 days mortality was 15% (155 pts), while 23.8% after 90 days (245 pts). The following laboratory parameters proved to be associated  to short-term mortality risk in univariate and confirmed as independent factors in multivariate analysis: chloride (OR 2.111, p = 0.001); sodium (OR 1604, p = 0.037); RDW (OR 1.197, p = 0.001); troponin (OR 1.005, p = 0.001); BNP (OR 1.193, p = 0.001). The cumulative score reached in the nomogram by the five parameters found to be predictive appeared directly related with the risk of 30 days mortality. The discriminatory ability of final model was validated by AUC (0.79) and further confirmed with a bias-corrected AUC in a 20000 sample bootstrap (0.78). Finally, as shown by Kaplan-Meier curves, higher risk probability calculated in the nomogram were associated even with higher 90 days mortality (Log-Rank test p < 0.001).       

 

Conclusion

Laboratory parameters collected at the ED observation time, when combined in a nomogram model, could have  a reliable prognostic impact and predict the short and middle-term mortality  in patients with ADHF. 


Gianni TURCATO, Dr Antonio BONORA (VERONA, Italy), Massimo ZANNONI, Alberto RIGATELLI, Giorgio RICCI
E-Poster Area

"Sunday 24 September"

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PH1 -S5
14:35 - 14:55

E-Poster Highlight Session 1 - Screen 5

14:35 - 14:40 #10613 - Mortality prediction in geriatric patients with dengue fever.
Mortality prediction in geriatric patients with dengue fever.

Background: Geriatric patients have high mortality for Dengue fever (DF). However, there has been no adequate predictive tool to predict mortality in this population.  

Objective: We aimed to develop a simple tool by combination of independent mortality predictors to predict mortality in geriatric patients with DF.

Methods: We conducted a retrospective case-control study in a tertiary medical center during the DF outbreak in Taiwan in 2015. All the geriatric patients (≥ 65 years) who visited the study hospital between September 1, 2015 and December 31, 2015 were recruited into this study. Variables including demographic data, vital signs, symptoms and signs, past history, living status, laboratory data, and outcome were included. We used univariate analysis first to identify variable with p < 0.1 and then recruited these variables for multivariate logistic regression analysis to investigate independent mortality predictors. Finally, we combined the independent mortality predictors to predict the mortality.

Results: In total, we recruited 627 geriatric patients with DF including 27 deaths and 600 survivals, which formed the mortality rate with 4.3%. After univariate and multivariate logistic regression analysis, severe coma (GCS ≤ 8; adjusted odds ratio [AOR]: 11.36; 95% confidence interval [CI]: 1.89–68.19), chronic bedridden (AOR: 10.46; 95% CI: 1.58–69.16), GOT > 1000 U/L (AOR: 96.08; 95% CI: 14.11–654.40) and serum creatinine > 2 mg/dL (AOR: 6.03; 95% CI: 1.50–24.24) were independent mortality predictors. When we combined the predictors together, we found that the sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) for patients with ≥ 1 predictor were 70.37%, 88.17%, 21.11%, and 98.51%, respectively. For patients with ≥ 2 predictors, the sensitivity, specificity, PPV, and NPV were 33.33%, 99.44%, 57.14%, and 98.51%, respectively.

Conclusions: We combined independent mortality predictors to predict mortality in geriatric DF and found that it had a good specificity and NPV. When geriatric patient with DF has none of the predictor, his/her survival opportunity is 98.51%. When geriatric patient with DF has ≥ 2 predictors, his/her mortality risk is 57.14%. The combination of mortality predictors could help us to make decision for geriatric patients in the future.


Feng-Kai CHAN (Tainan, Taiwan), Hung-Sheng HUANG, Chien-Cheng HUANG, Chien-Chin HSU
14:40 - 14:45 #11312 - Top-cited article on point-of-care ultrasound in emergency medicine: the research focus and evolution.
Top-cited article on point-of-care ultrasound in emergency medicine: the research focus and evolution.

Background:

Point-of-care ultrasound (POCUS) was increasingly applied in emergency medicine (EM) in the past decades. The evolution of application and research focus of POCUS was not studied. 

Methods :

  This study was an observational study. All articles and cited times were retrieved from Web of Science(WoS) database. The search term was “(Ultrasonography OR ultrasound OR sonography) AND (Point-of-Care Systems OR point-of-care OR POCUS OR bedside OR emergency)”.

  The articles were sorted by cited times in four time frames: overall since publication, average, recent 5 and 3 years. Two emergency physicians independently reviewed the top 100 most-cited articles in each group to determining their study focus. The country of origin, journal, publication year, field of POCUS, and cited times were recorded. The temporal trend of cited times of top cited articles classified by study focus were used to evaluate the evolution of research focus. The trend of POCUS-related publication numbers was analyzed by linear regression. The average cited times difference between four time frames were analyzed by Wilcoxon rank-sum test.

Result:

Total of 7860 POCUS-related articles were retrieved and the number increase from 8 in 1990 to 754 in 2016. The increasing rate of publication numbers was 27.3 (p-value < 0.001, 95% CI = 23.8 to 30.8).(Figure. 1) The distribution of numbers of cited times in each timeframe figures out the top-100 most cited articles contribute 12-14.3% total citations. Only 1% in all articles were cited more than 10 times in recent 3 years. In the other hand, the top-100 cited articles in this group were at least cited 29 times. The top-3 popular fields of application were thoracic, trauma, and cardio-vascular in time-frame of overall period. However, in group of recent 3-years or 5-years, thoracic, procedure guidance, and cardiovascular are top-3 field of applications.(Table 1) The distribution of annual cited times of each field of POCUS applications also revealed the most popular field evolved from trauma to thoracic ultrasound. (Figure 2)  More than three quarters of top-100 most cited articles were conducted by authors in United states, Italy, and France. Most of top-100 most cited articles were published on journals of critical care medicine and emergency medicine.

Discussion with conclusion:

POCUS is a rapid growing research field in EM. The research focus of POCUS study in EM evolve from trauma alone before early 2000 to a variety fields including thorax, procedure, and cardiovascular. (Figure 2) The list of top cited articles provided the developing milestone of POCUS in EM and a guide to facilitate EM physicians in future study.


Shao-Feng LIAO, Ching-Hsing LEE, Pai-Jung CHEN (Taipei, Taiwan)
14:45 - 14:50 #11440 - Acceptability of McGrath video laryngoscope in a pre-hospital setting.
Acceptability of McGrath video laryngoscope in a pre-hospital setting.

Introduction:

Use of video-laryngoscopes is now highly recommended in operating rooms. At pre-hospital level, where operating conditions are very specific, there are no recommendations and studies show that it could bring an added value for difficult airway management.

The objective of our survey was to evaluate the acceptability of a new tracheal intubation (TI) technique among pre-hospital healthcare professionals (nurses and doctors).

Material and Methods:

29 physicians and nurse anesthetists were recruited. They each performed a series of 8 TI with an adult manikin, using an Eschmann tracheal tube introducer. TI were performed, alternatively with direct laryngoscopy (DL) and McGrathâ video laryngoscope (McG) in a difficult airway management scenario (immobilized cervical spine). Four attempts were performed for each procedure.

They filled in a questionnaire with following: socio-demographic variables (age, gender), and questions about their daily practice: number of performed TI per year, number of difficult TI per year, if they already used a Fastrach, heard about McG and already used one. Finally, they were asked if they considered the McG as handy, if McG improved glottis vision, if it reduced traction forces, improved the position of the tube and facilitated TI on a scale from 0 (no) to 4 (yes). Data are presented as means and percentages.

Results:

Mean age was 42 years old (ranging from 26 years old to 56), with 55 % of male. 55% performed more than 10 TI per year, and 14% more than 5 difficult TI per year. 55% used a Fastrach. 62% already heard about McG and 35% already used one.

27 out of 29 participants (96.42%) reported McG use as handy (3 and 4 scores on the numeric scale), 25 (86.41%) participants stated that it improved glottis vision, 20 (71.43%) that it allowed reduction of traction forces, 13 (44.83%) that it improved tracheal tube positioning and 19 (65.55%) that it facilitated tracheal intubation.

Conclusion:

Pre-hospital professionals already used video-laryngoscopes in 1/3 of cases whether in their daily practice or during simulation sessions on manikins. They considered it as handy, with a better visualization of glottis and reduction of forces, but they were more divided when considering the improvement of positioning the tracheal tube and facilitating TI. 


Margot CASSUTO (Garches), Armelle SEVERIN, Anna OZGULER, Rosine BONNET, Michel BAER, Thomas LOEB
14:50 - 14:55 #11597 - Antibiotic Prophylaxis for Chest Drain Insertion in the context of Trauma.
Antibiotic Prophylaxis for Chest Drain Insertion in the context of Trauma.

Background/ Aim

Closed tube thoracostomy (TT) insertion for trauma patients is associated with an infectious complication rate for empyema, pneumonia and wound infection of 5.8-13%. The British Thoracic Guidelines (BTS) recommend prophylactic antibiotic use. However, implementation of this recommendation is variable.

Standard

BTS advises that antibiotic prophylaxis should be considered at TT insertion in the context of trauma.

Methods

A retrospective case review of all patients who received a TT in UHNM Emergency Department, over the 18 month period from April 2013 and September 2014 was conducted. In total, 84 patients (23 female, 61 male) with an average age of 47.9 years and ISS score of 20.1 were identified from data submitted by UHNM for TARN audit purposes. Their medical notes were requested and used for data collection.

Results

A ratio of 1:7.4 for penetrating vs bunt injury was found. In total, 22/84 patients (28.6%) developed an infectious complication attributable to TT. Of these, 12 had not received prophylactic antibiotics. Overall, the likelihood of acquisition of an infectious complication when given prophylactic antibiotics was associated with an odds ratio of 0.225 (CI 0.079-0.631) and a NNT of 3. Thus, support for the use of antibiotic prophylaxis for TT in the context of trauma was found, in concordance with BTS guidance.

Conclusion

As supporting evidence was found, guidance was produced, advocating prophylactic use of Co-Amoxiclav for patients requiring TT insertion due to trauma. This is currently, being proposed for inclusion in UHNM’s Emergency Medicine guidelines.


Sophie BURNAGE (Stoke-On-Trent, United Kingdom), Ruth KINSTON, Dave COOPER
E-Poster Area

"Sunday 24 September"

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PH1 -S1
14:35 - 14:55

E-Poster Highlight Session 1 - Screen 1

Moderators: Cornelia HÄRTEL (Medical Director of the ED, Consultant in EM, Director of Medical Education in EM) (STOCKHOLM, Sweden), Felix LORANG (Consultant) (Erfurt, Germany)
14:35 - 14:40 #11298 - Place of Simulation in the initial training of French emergency physicians: national observational and descriptive study.
Place of Simulation in the initial training of French emergency physicians: national observational and descriptive study.

Background: Simulation appears to be now an essential tool for the training of both technical and non-technical medical skills. It allows to respect the ethical statement: “Never the first time on a real patient”. Currently, integration of simulation in training programs is not harmonized between French Medicine Faculties. The corresponding framework remains to be defined in anticipation of the creation of the diploma of Emergency Medical Specialty planned for fall 2017.

Objective of the study: This investigation addressed the use of simulation in French initial formation in Emergency Medicine. It was intended as a first step toward establishing a simulation-based training program.

Material and Methods: This observational study was multicentric. A questionnaire was sent by email to all coordinators of Emergency Medicine initial formation in France. It included quantitative and qualitative items on general context, structure and the content of the simulation-based training. Data were compiled with Excel software (Microsoft Inc.)

Results: Twenty-five out of 29 university answered the questionnaire. Among those, 23 (92%) used simulation. 22 of them used High-Fidelity simulation and 21 procedural simulation.

The most involved application fields were cardiac arrest (22), shock state (21), chest pain, tachycardia (20), severe trauma and traumatic brain injury (17).

The most practiced technical procedures were intubation (22), difficult intubation (21), mechanical ventilation and intra-osseous access (18).

Median time was 2.5 days of simulation by year. In 12 centers (52%), the training staff had dedicated time and 15 centers (65%) benefited from remunerated staff. Finally, 12 centers (52%) were in agreement with the statement. “Never the first time on a real patient”.

Discussion and Conclusion: Simulation use in French Emergency Physicians initial training is heterogeneous. The main limitation of our study was the absence of response from 4 faculties. Generally, responding coordinators agreed on the main situations and techniques to be taught. As in other countries, promotion of simulation seems to be consensual. However, effective deployment remains difficult due to material investment, formation and availability of staff. This study could provide a basis for the establishment of a French national simulation-based training program.


Miléna ALLAIN, Vincent KUCZER, Céline LONGO, Eric BATARD, Philippe LE CONTE (Nantes)
14:40 - 14:45 #11496 - The value of tracheal and chest ultrasound in confirmation of endotracheal intubation in cases of cardiac arrest and polytrauma patients.
The value of tracheal and chest ultrasound in confirmation of endotracheal intubation in cases of cardiac arrest and polytrauma patients.

Background: Securing theairway by endotracheal intubation is a fundamental skill in emergency medicine. Unrecognized misplacement of enodotracheal tube can lead to morbidity and mortality with reported incidence of 2.9- 16.7 %.

Methods: the present study included 57 adult patients admitted to the emergency department at Alexandria main university hospital due to polytrauma or cardiac arrest. The value of tracheal and chest ultrasonography in confirmation of correct endotracheal intubation was evaluated and compared to the conventional method which included 5 points auscultation of the chest and epigastrium in addition to qauntitative waveform capnography. The sensitivity and specificity of the ultrasound using methods were calculatd. Moreover, the value of tracheal and chest ultrasonography in confirmation of endotracheal intubation without interruption of chest compressions in cases of cardiac arrest was noticed. Judgement of endotracheal tube position with capnography was done after tracing 5 subsequent normal waves of capnogram; mainstream capnography was used. Also, the time consumed to record the first capnography reading was reported and compared to the ultrasound using methods. Endotracheal tube placement confirmation by tracheal ultrasound was judged when 2 hyperechoic parallel lines replace the multiple reverbation artefacts at the site of the trachea by using a linear high frequency probe positioned horizontally just above the suprasternal notch. Tracheal ultrasound was done realtime as the tube was inserted. Pleural sliding sign was visualized by placing a linear high frequency probe in the second intercostal space midclavicular line, and fourth intercostal space midaxillary line on both sides of the chest. Finally, 5 points auscultation was done by bilateral auscultation at the midclavicular and midaxillary lines and epigastrium.

Results: There was correlation with significant kappa value of 0.8 between the novel techniques using ultrasound and capnography. Tracheal ultrasound had a sensitivity of 96.4% and specificity of 100%, while visualization of pleural sliding sign had a sensitivity of 92.86% and specificity of 96%  in confirmation of correct endotracheal tube placement when compared to capnography. The time consumed to confirm correct tracheal tube position was significantly shorter with tracheal ultrasound (19.7± 7.3) seconds,relative to capnography (182.2±166.7)seconds,5 points auscultation (73.2± 25.11)seconds, and visualization of pleural sliding bilaterally(35.4± 5.81)seconds, with significant p value of <0.001 for ultrasound using methods and 0.002 for 5 points auscultation.

Discussion: Airway ultrasound may be considered important in confirmation of correct endotracheal tube placement especially in cases of cardiac arrest where it may be more appropriate than capnography. There was no interruption of chest compressions on using tracheal ultrasound, but interruption might occur on using chest ultrasound and auscultation.


Asmaa ALKAFAFY (Alexandria, Egypt), Nagwa ELKOBBIA, Salah ELTAHAN, Moustafa ABDEL-AZIZ, Alaa-Eldin ABDALLAH
14:45 - 14:50 #11524 - Predictors of pediatric intensive care admission in patients with severe-moderate bronchiolitis.
Predictors of pediatric intensive care admission in patients with severe-moderate bronchiolitis.

Background: Bronchiolitis is a lower respiratory tract infection affecting principally the small airways. The disease is the most common cause of infant hospitalization during the winter months. Assessment of clinical severity is important in daily pediatric emergency department practice. The purpose of the study was to determine the clinical, laboratory and radiological predictors of the severity of bronchiolitis in children for the admission to the pediatric intensive care unit.

Methods: The patients were aged between 6 weeks and 24 months presenting to the pediatric emergency department of the Health Sciences University, Tepecik Teaching and Research Hospital with acute bronchiolitis between 01.01.2014 and 31.12.2015 were evaluated retrospectively. Vital signs and clinical findings were determined before interventions such as suctioning, antipyretic medication, oxygen support, and I.V. fluid. Clinical Severity Score (0–3 points: mild; 4–8: moderate; and 9–12 points: severe disease) based on respiratory rate, wheezing, retraction, and general condition is used routinely in the department. Children with severe bronchiolitis and those with moderate disease managed up to six hours in observation unit were included the study.  

Results: A total of 12 854 infants with bronchiolitis were evaluated; 925 of them (mean age: 6.2 ± 4.4 months, male/female: 587/338) included the study. Fifty-five patients (5.9%) were admitted to the pediatric intensive care unit; 19 of them were intubated and mechanically ventilated.  Six patients died (0.6%). Premature birth, underlying chronic disease, body temperature >38 °C, tachycardia (0-12 months> 160 / min, 12-24 months: 150 / min), tachypnea (1-12 months > 60 / min; 13-24 months > 50/min); oxygen saturation <90%, physical examination findings of significant dehydration (5% or more), nasal flaring, crackles in lung auscultation, pH <7.30 and presence of atelectasis in chest X-ray were found more frequently in the infants admitted to the pediatric intensive care unit (p <0.05). In the logistic regression analysis, oxygen saturation <90% (p: 0.001; OR: 4.648; 95%CI: 1.918-11.124), tachycardia (p: 0.001; OR: 4.619; 95%CI: 1.918-11.124), pH <7.30 (p: 0.003; OR: 6.773; 95%CI: 1.911-23.999), nasal flaring (p: 0.001; OR: 4.734; 95%CI: 1.942-11.537), and crackles in lung auscultation (p:0.009; OR: 3.150; 95%CI: 1.325-7.486) were the most significant parameters. 

Conclusion: Significant tachycardia, nasal flaring, crackles, low oxygen saturation, and acidosis were the most powerful predictors of intensive care unit need in patients with moderate-severe bronchiolitis.


Dr Murat ANIL (Izmir, Turkey), Ayse Berna ANIL, Fulya KAMIT CAN, Esin ALPAGUT GAFIL, Yuksel BICILIOGLU, Gamze GOKALP, Emel BERKSOY
14:50 - 14:55 #11129 - Under- and over-treatment of hypoxemia in a rwandan emergency department : baseline and training intervention results.
Under- and over-treatment of hypoxemia in a rwandan emergency department : baseline and training intervention results.

BACKGROUND:


The World Health organization (WHO) recognized oxygen as an essential medication. Recent studies have shown a correlation between, not only hypoxemia, but also hyperoxia and possible worse outcomes. As part of a study on the acute respiratory distress syndrome in a Rwandan referral hospital, we screened every adult patient with pulse oximeters for a 6 weeks period, we found that 12% of adult inpatients were hypoxemic (SpO2<90%); and 49% of these died. We observed that some patients received oxygen without titration and that there were few pulse oximeters available. We hypothesized that both under- and over-treatment of hypoxemia in adults would be prevalent in the emergency room of this Rwandan referral hospital, and that rational use of oxygen resources may improve through training and provision of pulse oximeters.

 

METHODS:

Over a five-week period in early 2017, we screened 845 patients in the Emergency Department (ED) of the University Teaching Hospital of Kigali (CHUK) for hypoxemia and oxygen therapy. Information on basic demographics and oxygen therapy, co-morbidities and vital status at discharge were collected. After completing baseline data collection, we provided pulse oximeters and conducted a didactic training on their use with target SpO2 of 90-95%. Training included a pre-test, post-test and skills assessment on oxygen titration and pulse oximeter use.

 

RESULTS:

During the baseline data collection, 182 of the 845 patients (21.5%) were either hypoxemic or on oxygen therapy; 23 (13%) of these were found to be hypoxemic (SpO2<90%): 14 without and 9 with oxygen therapy. 125 (69%) had oxygen saturations above our target value of SpO2≤95%. Only 6 (4%) of patients had documentation of therapeutic oxygen goals in their medical charts. The demographics, co-morbidities and outcome data revealed: 121 (67%) male patients; a median age of 34 years; 20 (11%) patients had a history of chronic pulmonary disease (asthma, tuberculosis, COPD) and that 57 (31%) patients passed away before hospital discharge. After completion of baseline data collection and intervention training, physician and nursing knowledge scores improved by 25% and 19%, respectively.  On the skills assessment after training, average scores were 92% for nurses and 85% for resident physicians.

 

DISCUSSION:

Of all patients present in this referral hospital ED, 21.5% of patients were hypoxemic and 81.3% of these were either under- (13%) or over- (69%) treated with oxygen. A brief didactic training session improved knowledge about oxygen therapy management. We will follow up to look at both knowledge retention and oxygen therapy outcomes at 4- and 12-weeks post-intervention.


Victor MORIAU (Brussels, Belgium), Tori SUTHERLAND, Jean-Louis VINCENT, Joseph NYONZIMA, Fabien GUÉRISSE, Elisabeth D. RIVIELLO
E-Poster Area

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PH1 -S2
14:35 - 14:55

E-Poster Highlight Session 1 - Screen 2

14:35 - 14:40 #9852 - Intravenous Caffeine Citrate versus Magnesium Sulphate for Pain Control of Acute Migraine Headache.
Intravenous Caffeine Citrate versus Magnesium Sulphate for Pain Control of Acute Migraine Headache.

Objective

The objective of this study is to compare intravenous caffeine citrate with magnesium sulphate for the treatment acute migraine.

Design

We conducted a prospective clinical trial.

Setting

This study was conducted from January until May 2016 in two educational medical centers of Shahid Beheshti University of Medical Sciences (Shohadaye Tajrish Hospital and Imam Hossein Hospital), Tehran, Iran

Subjects

The study included 70 patients who meet the migraine diagnosis criteria of the international headache society criteria. Depending on to which hospital visited, patients were allocated to receive 60 mg intravenous caffeine (n=35 patients) or 2 g intravenous magnesium sulphate (n=35 patients).

Methods

Patients were asked about their visual analog scale (VAS) pain score on admission. Patients with VAS pain score >4 were enrolled. After one and two hours of drug administration, patients were asked about their pain score according to VAS. Mann-Whitney U test and Wilcoxon test were used to analyze differences in VAS pain scores

Results

Both intravenous caffeine citrate and intravenous magnesium sulphate reduced VAS pain scores significantly but the Magnesium sulphate group showed better improvement than the Caffeine citrate group after one hour (P<0.001) and after two hours (P<0.001).

Conclusions

Our results suggest that 2 g intravenous magnesium sulphate is superior to intravenous caffeine citrate 60 mg for short term management of migraine headache. Further well designed randomized controlled studies are warranted to confirm these findings.


Alireza BARATLOO (Tehran, Islamic Republic of Iran), Alaleh ROOHIPOUR, Sahar MIRBAHA
14:40 - 14:45 #11185 - Cervical spine clearance in patients with unreliable clinical exam: delays and complications.
Cervical spine clearance in patients with unreliable clinical exam: delays and complications.

OBJECTIVE: To describe the timing of cervical spine clearance in blunt trauma patients with unreliable physical exam on presentation and identify complications potentially associated with delays in clearance.

PATIENTS AND METHODS: A prospective observational cohort study was carried out in an academic level 1 U.S. Trauma Center from November 2016 to March 2017. An institutional protocol allowing cervical spine clearance exclusively by CT of the cervical spine (CTCS) was in place prior to commencing this study. We included adult blunt trauma patients admitted with a cervical collar and an unreliable clinical exam (as defined by the NEXUS-criteria), who were eventually found to have no cervical spine injury. We excluded patients with cervical spine injuries requiring a collar as the treatment. The primary outcome was time from Emergency Department (ED) arrival to collar removal. Secondary outcomes included time from ED arrival to CTCS and in-hospital complications potentially related to the cervical collar.

RESULTS: A total of 43 patients were included. The median age was 58 years (interquartile range (IQR): 36-75), and 33 (76.7%) were males. 39 (90.7%) had associated injuries, mostly in the brain (25 [59.5%]) and chest (22 [51.2%]). The main reasons for an unreliable physical exam were a GCS≤13 (18.6%), distracting injuries (48.8%), cervical spine tenderness (16.3%), alcohol/drugs (9.3%), or a combination. The median time from ED arrival to CT-spine was 62 minutes (IQR: 44-91) and the median time to collar removal was 493 minutes (IQR: 306-1526). MRI was used to rule out injury in 2 (4.7%) with a CTCS suspicious for injury and an additional 5 (11.6%) patients for other reasons. A total of eleven (25.6%) patients developed complications before collar removal; 9 (20.9%) aspirated, 7 (16.3%) developed infections, and 5 (11.6%) had delirium. Patients with GCS ≤ 13 on admission had CT-spine performed earlier (median: 52 vs. 71 minutes, p=0.03), but their collar removed later (median: 1148 vs. 409 minutes, p<0.001) than patients with a GCS > 13. Additionally, patients with GCS ≤ 13 had a longer duration of hospital stay (median 6 vs. 4 days, p<0.001), but did not develop more complications before collar removal (38.9% vs. 16.0%, p=0.16) compared to patients with GCS > 13.

CONCLUSION: Even if CTCS confirms the absence of injury early on, there is a prolonged period of time before the collar is removed in patients with unreliable clinical exam, especially in patients with GCS ≤13. While waiting for clearance, patients develop complications, which may be related to the collar. Protocols should be developed for earlier collar removal to avoid associated morbidity.


Josefine Stokholm BAEKGAARD (Copenhagen, Denmark), Trine Grodum ESKESEN, Jacob STEINMETZ, Lars S. RASMUSSEN, David R KING, George C VELMAHOS
14:45 - 14:50 #11547 - Health planning and migratory phenomena: are we already late?
Health planning and migratory phenomena: are we already late?

The number of world-wide migrants has risen from 150 million in 2000 to 214 million in 2010, and projections for the coming years confirm the trend. By the year 2050, 405 million people will be migrants. In 2014, the total number of regular immigrants in Italy was over 5 million, with an impact on the resident population of 8.2%. The irregular immigrants in Italy are 500-700,000 and tending to lower. In the years 2015 and 2016, our team tried to answer two questions: Are irregular foreigners subject to more illnesses than Italians? Do irregular foreign citizens expose us to the risk of illness above those we are usually exposed to?

In 2015, the 19% of accesses to Emergency Department of Verona were foreigners, in 2016 the percentage increased to 20.5%. The number further increases if we consider only gynecological (35%) and pediatric (23%) accesses. Patients are mainly from Romania (6601) followed by Morocco (3124) and Sri Lanka (3031). Other numerically important nationalities are Nigeria, Moldova and Albania. The access priority assigned to the triage is similar to that of Italian patients, with a slight decrease in yellow codes, and an increase in white codes, which is not significant. Discharges are similar to those of Italian patients (77% vs. 78%), but a significant amount (40% ) of foreign patients are hospitalized in gynecology and pediatrics.

The most common causes of hospitalization are respiratory diseases, gastrointestinal disorders, skin diseases, mostly from precarious living conditions. Compared to Italians, immigrants are generally young and healthy. They become ill after arrival in Italy, due to the change in dietary habits. Among the major disorders: diabetes, gastrointestinal disorders, hypertension: diabetes affects mainly the Romans and Senegalese, while the Ukrainians, especially women, are affected by high blood pressure.

Study data shows that most of those arriving in Italy are in good health. Once in Italy, the state of health is reduced, for the many risk factors related to generally poor living conditions. Foreigners are reluctant to adhere to screening and diagnostic screening programs - hence the higher vulnerability to age-related pathologies.

Conclusions:

1. Immigrants, when arriving in Italy, are generally healthy. The migrant is strong, young and more stable psychologically.

2. Health problems (from discomfort, injury at work) are largely attributable to uncertain integration policies, difficulties in access to services and communication, endangering the "health heritage" the immigrant is carrying.

There are 196 nationalities belonging to the new residents: complexity of cultures, uses, relational modalities that insist on our territory and are the forerunners of changes in the daily life of collective life: considering these new factors, we need a serious health planning for the next years. 


Lucia ANTOLINI (VERONA, Italy), Chiara BOVO, Roberto CASTELLO, Massimo ZANNONI, Giorgio RICCI
14:50 - 14:55 #11570 - Comparison of the prophylactic effects of N-acetylcysteine and normal saline in contrast nephropathy.
Comparison of the prophylactic effects of N-acetylcysteine and normal saline in contrast nephropathy.

Aim: N-acetylcysteine (NAC) was compared with Normal Saline (NS) in terms of efficacy for the prevention of contrast-induced nephropathy on ED patients in this study. Patients with mild renal function loss were studied.

Material and Methods: Patients were randomly divided into two groups; “High dose NAC” and “Saline”. In first group (High dose NAC), 150 mg/kg NAC (Asist© - Nacosel©) was administered intravenously in 30 – 60 minutes with 2 – 4 mL/kg/hr – 0.9% NaCl immediately before contrast agent application. After contrast (Omnipque© 300 mg/100 ml) imaging 50 mg/kg NAC was administered in 2 – 4 hours with 1-2 mL/kg/hour – 0.9% NaCl intravenously. In second group (saline) 6-8 mL/kg/h 0.9% NaCl was administered intravenously in 60 – 120 minutes immediately before contrast agent application. After contrast imaging 3 – 4 mL/kg/h 0.9% NaCl (up to 2000 cc) was administered intravenously in 4 – 6 hours. Serum creatin levels checked immediately before and after 24 and 72 hours contrast agent application. Increase of creatinin value %25 or more than 0,5 mg/dL compared with value on admission to ED was considered to be development of contrast-induced nephropathy. The creatinin levels checked on ED admission (Before contrast agent application), 24th and 72nd hours after contrast agent application. Results divided into three groups according to changes on their creatinin levels; “Decrease on creatinin levels %25 or more”, “no change on creatinin levels” and “Increase on creatinin levels %25 or more than 0,5 mg/dL”.

 Results: None of the patients in the first group were observed nephropathy. Furthermore, the

creatinin levels were in normal range on 72nd hours after contrast agent application in high dose NAC group whose first creatinin levels were 1,2 – 1,8.

 Conclusion: The result of study, for preventing of contrast inducing nephropathy; high dose NAC application is more effective and usable than NS, in patients with mildly impaired renal function on ED.


Omer Faruk AYDIN (Istanbul, Turkey), Eren GOKDAG, Ozlem GUNEYSEL
E-Poster Area

"Sunday 24 September"

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PH1- S4
14:35 - 14:55

E-Poster Highlight Session 1 - Screen 4

14:35 - 14:40 #11715 - Evaluation of the relevance of qSOFA for the management of severe sepsis in elderly patients in Emergency department.
Evaluation of the relevance of qSOFA for the management of severe sepsis in elderly patients in Emergency department.

Introduction :

Early detection and management of sepsis has  significantly improved its prognosis. Actually it is recommanded to use predictive score as  qSOFA (Quick Sepsis-related organ failure assessment), which is a score that evaluates 3 clinical datas: Upper function disorders ,  Respiratory Rate ≥22 C / min and  Systolic blood pressure ≤ 100mm hg in order to detect patients with a major septic risk. However, elderly subjects have particular status and are more sensitive to the dysregulation of their homeostasis. They are more likely to have high qSOFA outside severe sepsis.

The objective of this study  is to study the relevance of qSOFA in the prediction of severe sepsis in a population older than 65 years.

Methods :

Prospective observational study carried out in our Emergency department over a period of 2years.We used Data from our local register RESSUS. The subgroup of elderly patients : age ≥65 was particularly studied. The demographic, clinical, and evolution features of these patients were noted, including orientation and final diagnosis.

Results :

216 patients were included in our local registry, and 121 patients over 65 years old  (55) are included in this studywe had  63 men, a sex ratio of 1.08. The mean age was 75 years (min 65 years and max 97 years), 42% were diabetics (n = 51), 58% had hypertension ( n = 70), 11 patients were known to have chronic respiratory insufficiency (9%) and 24% have chronic renal failure (n = 30). 25% of patients with glasgow Coma scale <14, 54 patients had a RR≥22 (44.7%) and 33% had a SBP≤100mmhg (n = 41). Thus, 15.7% of the patients presented a qSOFA≥2 (n = 19); A correlation between qSOFA> 2 and SOFA> 2 is significant P = 0.014. A sensitivity of 78% was retained. Of the 19 patients with qSOFA ≥2, 4 had a SOFA <2 or a false positive rate of 21%.

Conclusion

Our study shows that in elderly subjects qSOFA is more specific than sensitive despite its ease of use and the opportunity it offers for rapid therapeutic initiation. The use of SOFA score remains more relevant and more predictive of severity for this age group.

 

 


Ali OUSJI (Sousse, Tunisia), Asma ZORGATI, Lotfi BOUKADIDA, Houda BEN SALAH, Ines OUAZ, Riadh BOUKEF
14:40 - 14:45 #11725 - Assessment of the management of wake-up strokes in our emergency department.
Assessment of the management of wake-up strokes in our emergency department.

Introduction:

Wake-up strokes are defined as an acute neurologic deficit when waking up. They represent 25% of all ischemic strokes. the exact time of symptom onset remains unspecified, so there is a problem in therapeutic decision. Studies propose different protocols for management  of ordinary ischemic strokes. Academic societies considered as arbitrary schedule the last time on which the patient has been seen having a normal mobility. Recommandations considered MRI imaging essential for therapeutic decision.

The objective is to study the clinical, the management and the evolutionary characteristics   of wake-up strokes in order to propose a particular thrombolysis protocol for wake up strokes.

Patients and methods:

 observational  study conducted in our emergency department  over a period of 17 months ( October 2015  ==> February 2017), we used the data concerning the subgroup wake-up stroke from our local registry. We noted clinical, radiologic, therapeutic and evolutionary characteristics of these patients and in particular the orientation and the short-term prognosis.

Results: 

In our registry 519 patients presenting a stroke have been included of wich 60 were "wake-up strokes" (21,6%).  Women represent 53% (n=32), sex ratio=0,53. The average age is 61 year (31 to 95 years), 41%(n=25) are diabetic, 71% (n=43) are hypertensive and 30% (n=18) have had a history of stroke (AVC or AIT). 76%  of the patients (n=46) have come to the emergency department by their own against 19%  transferred by an ambulance and only 5% (n=3) via SAMU. The initial NHISS score was > 10 for 9 patients (15%). Considering the last schedule with a normal mobility, 20% of patients (n=12) came on time allowing the thrombolysis alert to be triggered, but only one patient has benefited of the thrombolysis because the schedule remained uncertain for the majority of other patients and the RMI was not available. A CT scan was done within an average time of 2h38mn +/- 15 mn, the average ASPECT score was 7 and signs of constituted stroke was observed in 7 cases (11%). The decision was to return at home with a external follow-up for 42 patients (70%). The rate of hospitalization in neurology department was 28%, one patient was transferred in an intensive care unit.

The only patient thrombolyzed was a 43 years old man , having a deficit of his left hemicorps with a NHISS score of 10. the exact time of symptom onset was uncertain and the last time from a normal mobility was 5 hours. The alert for thrombolysis was triggered and an MRI was made urgently allowing to make the thrombolysis with succes (NHISS score = 2 after 24 hours).

Conclusion:

Patients waking up with stroke symptoms represent a group of stroke patients who are currently excluded from intravenous thrombolysis . We suggests that a relevant proportion of patients with wake-up strokes might benefit from reperfusion treatment and be promising candidates for intravenous thrombolysis. Their prognosis can be more better.

 

 


Rim YOUSSEF, Asma ZORGATI, Sana MABSOUT, Rabaa SABBEGH, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
14:45 - 14:50 #11742 - The use of complementary exams for the positive diagnosis of acute appendicitis: gender difference.
The use of complementary exams for the positive diagnosis of acute appendicitis: gender difference.

INTRODUCTION: The acute appendicitis (AA) is currently the most common abdominal emergency. It should be evoked for any acute abdominal pain, especially when the symptoms predominate in the sub-mesocolic stage.The positive diagnosis remains in some cases difficult especially in the case of feminal gender because of the multiple differential diagnoses mainly the gynecological and urinary pathologies.This leads to the use of more complementary examinations more than male case.The objective of this study was to determine whether if  there was a difference in the diagnostic and the use of complementary examinations between men and women in the acute appendicitis case. MATERIAL AND METHOD : It was a prospective study carried out from April 2014 to February 2017.It included 400 patients who consulted into the emergency department for abdominal pain for which the acute appendicitis diagnostic is likely. Biological analyzes , an abdominal ultrasound and sometimes an abdominal CT were request. The diagnosis of acute appendicitis was confirmed by an histological exam.RESULTS:  In our study, there was a slight male predominance with (52.8% male and 47.3% female). The middle age was 32 ± 29 years. The abdominal ultrasound was performed in 83% of both men and women. It had the same sensitivity (97%) but a better specificity for the female genus (76% versus 68%). The abdominal CT was performed in 68 of the patients, which represented 18% of cases in men and 14% of cases in women but there was no significant difference (p not significant). The CT has allowed the diagnosis of AA in 93% of the cases in men and 96% of the cases in women without any significant differences.CONCLUSION :Unexpectedly the presence of several differential diagnoses to women did not influence the prescription of complementary examinations in the diagnosis of acute appendicitis, thus there was not any statistical differences between both sexes at complementary examinations requested. 


Ikhlass BEN AICHA, Asma ZORGATI, Wael CHABAANE, Rabiaa KADDACHI, Chawki JEBALI, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
14:50 - 14:55 #11371 - Safety of a one-hour rule-out high-sensitive Troponin T protocol in patients with chest pain at the emergency department to exclude short-term major adverse cardiac events.
Safety of a one-hour rule-out high-sensitive Troponin T protocol in patients with chest pain at the emergency department to exclude short-term major adverse cardiac events.

Background: Reichlin et al. has validated a one-hour protocol, in which a serial measurement of troponin is performed one hour after the first, showing a safe rule-out for acute coronary syndrome (ACS). This protocol has been implemented in international guidelines. Our aim was to assess safety of this protocol when implemented in daily practice.

Methods: Patients with acute chest pain presenting to the ED of our hospital were included (May 2013 - October 2014, the Netherlands). Patients with a first troponin ≥ 0.012 ug/l and/or age >75 years were excluded. Hs-cTnT was measured at presentation (T0) and 1-1.5 hours after T0 (T1). Primary endpoint was the 6-week occurrence of major adverse cardiac events (MACE), defined as unstable angina (UA), acute myocardial infarction (AMI), percutaneous coronary intervention (PCI), significant stenosis managed conservatively, coronary artery bypass grafting (CABG) and death.

Results: Of the 374 analyzed patients, 16 patients (4.1%) developed 35 MACE, of which 19 UAs, 1 AMI (complication of PCI), 11 PCIs, and 4 significant stenoses treated conservatively. Of these 16 patients with endpoints, three patients (0.8%) were primarily discharged with non-cardiac chest pain, but returned within six weeks with unstable angina. Importantly, no patients experienced an AMI or died during follow-up.

Conclusion: No AMIs or deaths occurred after we introduced our one-hour hs-cTnT protocol to rule-out ACS in chest pain patients, but other MACE such as unstable angina occurred. We deem the protocol safe to be implemented in the ED in the Netherlands. 


Emma RÖTTGER, Sabrine DE VRIES-SPITHOVEN, Johannes REITSMA, Sander LIMBURG, Clara VAN OFWEGEN-HANEKAMP, Arno HOES, Judith POLDERVAART (Utrecht, The Netherlands)
E-Poster Area
15:00

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A12
15:00 - 16:30

Pulmonary (Cutting Edge)

Moderators: Panos AGOURIDAKIS (IRAKLION, Greece), Roberto COSENTINI (Head of Emergency Medicine) (BERGAMO, Italy)
Coordinator: Nikolas SBYRAKIS (Coordinator, Heraklion, Greece)
15:00 - 16:30 POCUS in dyspnoea: What does the probe add to the stethoscope? Dr Nicolas LIM (Consultant Emergency Medicine) (Speaker, Singapore, Singapore)
15:00 - 16:30 Asthma and COPD: Latest guidelines and practical tools for the Emergency Physician. Michael RADEOS (Speaker, USA)
15:00 - 16:30 Invasive Mechanical Ventilation: an update for the emergency physician. Helen ASKITOPOULOU (Chair Ethics Committee) (Speaker, Heraklion, Greece)
Trianti Hall

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B12
15:00 - 16:30

Trauma (How To)

Moderators: Anil CHOPRA (Canada), Burak KATIPOGLU (Faculty) (Ankara, Turkey)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
15:00 - 16:30 Paediatric trauma is different. Ross FISHER (Consultant Paediatric Surgeon) (Speaker, Sheffield)
15:00 - 16:30 Are we failing the frail falling? Katrin HRUSKA (Emergency Physician) (Speaker, Stockholm, Sweden)
15:00 - 16:30 How can I manage an urgent invasive procedure for a patient taking oral anticoagulants? Karim TAZAROURTE (Chef de service) (Speaker, Lyon, France)
Mitropoulos

"Sunday 24 September"

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C12
15:00 - 16:30

Education (Game Changers)
LIVE SCENARIOS! TEST YOUR DIAGNOSTIC SKILLS!

Moderators: Eric DRYVER (Consultant) (Lund, Sweden), Gregor PROSEN (EM Consultant) (MARIBOR, Slovenia)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
Speakers: Eric DRYVER (Consultant) (Speaker, Lund, Sweden), Caroline HÅRD AF SEGERSTAD (Senior consultant) (Speaker, Ystad, Sweden), Gregor PROSEN (EM Consultant) (Speaker, MARIBOR, Slovenia)
Scenario based training as the future European education perspective
Banqueting Hall

"Sunday 24 September"

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D12
15:00 - 16:30

YEMD - MSF

Moderators: Luca CARENZO (SIMULATION COMPETITION ONLY) (NOVARA, Italy), Aposotolos VEIZIS (Greece)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
15:00 - 16:30 Who is MSF. Aposotolos VEIZIS (Speaker, Greece)
15:00 - 16:30 What about Emergency Medicine in MSF. Victor ILLANES (Speaker, France)
15:00 - 16:30 How can I get involved. Luca CARENZO (SIMULATION COMPETITION ONLY) (Speaker, NOVARA, Italy)
Skalkotas

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E12
15:00 - 16:30

Disaster Medicine I
How to prepare doctors to face the new threats

Moderators: Pr Francesco DELLA CORTE (Head of Emergency Department) (Novara, Italy), Dr Abdo KHOURY (PROFESSEUR ASSOCIE) (Besançon, France)
Coordinator: Dr Abdo KHOURY (Coordinator, Besançon, France)
15:00 - 16:30 Damage control Ground Zero. Vitor Manuel LOPES FERNANDES ALMEIDA (doctor) (Speaker, viseu, Portugal)
15:00 - 16:30 Damage control resuscitation. Benoît VIVIEN (Adjoint du Chef de Service du SAMU de Paris, Responsable du SAMU Pédiatrique Régional IDF) (Speaker, Paris, France)
15:00 - 16:30 Training of Emergency Medical Teams. Luca RAGAZZONI (Scientific Coordinator) (Speaker, Novara, Italy)
MC-3

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F12
15:00 - 16:30

Free Papers Session 2

Moderators: Dr Thomas BEATTIE (Senior lecturer) (Edinburgh, United Kingdom), Anna SPITERI (Consultant) (Malta, Malta)
15:00 - 16:30 #10087 - OP010 Significance of the thrombo-inflammatory status-based novel prognostic score as a useful predictor for in-hospital mortality of patients with type B acute aortic dissection.
OP010 Significance of the thrombo-inflammatory status-based novel prognostic score as a useful predictor for in-hospital mortality of patients with type B acute aortic dissection.

Background: Inflammation and thrombosis are involved in the progression of acute aortic dissection (AAD). The aim of this study was to assess the prognostic significance of the Simplified Thrombo-Inflammatory Prognostic Score (sTIPS) in patients with early phase type B AAD.

Methods: We retrospectively reviewed 491 patients with type B AAD between November 2012 and September 2015. sTIPS was calculated using data obtained at the time of admission, and patients were assigned a score of 0, 1, or 2. Kaplan-Meier curves and multivariable Cox regression analyses were used to investigate the associations between the score and hospital survival.

Results: Of 491 type B AAD patients included in this analysis, 24 patients (4.9%) died while hospitalized. Compared to those with lower sTIPS, patients with higher sTIPS had higher rates of in-hospital mortality (P = 0.001). Kaplan-Meier analysis also showed that cumulative mortality was significantly higher in patients with higher sTIPS (P = 0.001). Multivariable Cox regression analysis further revealed that scores of 2 or 1 (versus 0) were strong predictors of in-hospital mortality (sTIPS 2: hazard ratio: 5.620, 95%; confidence interval [CI]: 1.320-16.167; P = 0.017; sTIPS 1: hazard ratio: 2.012, 95%; CI: 1.254-3.204; P = 0.043) after controlling for all of the confounding factors. Subgroup analysis showed sTIPS was also positively associated with the hazard of in-hospital mortality in patients with different therapies.

Conclusions: sTIPS was a useful tool for risk-stratifying type B AAD patients at admission for outcomes such as in-hospital mortality in the early phase.


Wan ZHI (Chengdu, China), Li DONGZE
15:00 - 16:30 #10839 - OP011 Impact of Beta-blockers on the clinical diagnosis of patients with pulmonary embolism.
OP011 Impact of Beta-blockers on the clinical diagnosis of patients with pulmonary embolism.

Introduction. The morbidity and mortality of patients with pulmonary embolism is high with 8 to 23 deaths per 100,000. In order to make the diagnosis, the emergency physician uses clinical scores that involve the presence or absence of a tachycardia. The objective of our study was to assess the impact of beta-blockers on the heart rate of patient with a pulmonary embolism.

Methods. We performed a retrospective, observational, monocentric study from June 2014 to May 2015. All consecutive patients admitted to our department with an objectived pulmonary embolism were included.

Results. Among the 117 patients included, more than a quarter was under beta-blocker (n = 31). The mean age was 68+/-17 years. Patients with beta-blockers were older than those without (respectively, 76+/-11 vs. 66+/-18 years, p = 0.03). The mean heart rate was lower in patient with beta-blockers than in those without (76.714 vs. 90.719 bpm, p <0.001, respectively). Moreover, regarding the heart rate item in the revised Geneva score, those with beta-blockers were more likely to have a heart rate < 75 bpm (42% vs. 19%, p = 0.015, respectively) and less likely > 95 bpm (13% vs. 41%, p = 0.04, respectively) than those without. However, for the sPESI score, there was no difference between the mean score of those with and without beta-blockers (respectively, 1.2+/-0.9 vs. 0.9+/-0.8, p = 0.104). Interestingly, regarding the heart rate item of sPESI score, none of the patient with beta-blocker had a heart rate > 110 bpm whereas 9 (10.5%) of those without beta-blocker had it (p = 0.11).

Conclusions. Our study showed that 26.5% of PE patient admitted in an emergency department were under beta-blockers. Moreover, PE patient with beta-blockers had a lower mean heart rate than those without. This could have an impact on the different scores used by emergency physicians to diagnose PE. Thus, 42% of PE patients with beta-blockers did not obtain the point assigned to tachycardia in the revised Geneva score. This could therefore have an impact on emergency physician diagnosis which could underestimated the PE score of some patient with beta-blocker. This results should be validated by multicentric and prospective studies.


Farès MOUSTAFA (Clermont-Ferrand), Bertrand DESMARIE, Nicolas DUBLANCHET, Coralie SERRANO, Simone HEUSER, Nadine BREUIL, Jeannot SCHMIDT
15:00 - 16:30 #10885 - OP012 A real life study of patients under direct oral anticoagulants admitted to an emergency department and their bleeding events.
OP012 A real life study of patients under direct oral anticoagulants admitted to an emergency department and their bleeding events.

Introduction. The use of direct oral anticoagulants (DOACs) is increasing due to an easier used and a decreased bleeding risk. The objective of our study was to describe the clinical characteristics of patients under DOACs, the type of hemorrhage and their management.

Methods. We performed a retrospective, monocentric and descriptive study on patients under DOACs and admitted to our emergency department between January 2014 and June 2015. We used the RATED registry (Registry of patient with antithrombotic agents admitted to an Emergency Department, NCT02706080) which is a monocentric, ongoing (from January 2014), observational registry of consecutive patients under antithrombotic drugs admitted to an emergency department.

Results. Of the 357 patients under DOACs included, 51 (14.3%) were under apixaban, 109 (30.5%) under dabigatran and 197 (55.2%) under rivaroxaban. Atrial fibrillation was the most frequent indication for DOACs (79.3%) with an average CHA2DS2-VASc score of 3.9 ± 1.8. The mean age was 73 ± 15 years with 78 ± 12 years for apixaban, 74 ± 13 years for dabigatran and 71 ± 16 years for rivaroxaban. Our cohort identified 211 (59%) prescribing errors related to the combination of a treatment which could increase the bleeding risk (33.6%), a dose not adapted to the age of the patient (28.0%), a dosage not adapted to creatinine clearance level (15.9%) or an additional treatment with antiplatelet agent for more than 1 year (13.3%). Of the 357 patients under DOACs, 64 patients (17.9%) were admitted for hemorrhage with 23 major bleeding (6.4%). Bleeding occurred in 8 patients (15.7%) under apixaban, in 13 under dabigatran (11.9%), in 43 (21.8%) under rivaroxaban with, respectively, 2-5-16 major bleeding. The management of those with major bleeding (n=23) was transfusion for 9 (39%) of them (5 under rivaroxaban, 3 under dabigatran and 1 under apixaban), reversion by prothrombin complex concentrate for 1 (4.3%) under rivaroxaban or by FEIBA for 4 (17.4%) under rivaroxaban.

Conclusions. Our study showed that more than half of patients under DOACs admitted to the emergency department had a prescription error and that only 1 major bleeding over 5 were treated with a reversal agent. Even if DOACs are easier to use, clinicians must be aware of interaction and contraindication, and must improve the management of major bleeding.


Farès MOUSTAFA (Clermont-Ferrand), Joel CHEDJIEU, Alain BARRES, Jennifer SAINT-DENIS, Jean ROUBIN, Nicolas DUBLANCHET, Julien RACONNAT, Jeannot SCHMIDT
15:00 - 16:30 #10899 - OP013 Importance of delay for management of STEMI: does the helicopter HEMS is better than ground transport with MICU ambulance? Analyze of the French region Centre Registry of Acute Coronary (CRAC) model.
OP013 Importance of delay for management of STEMI: does the helicopter HEMS is better than ground transport with MICU ambulance? Analyze of the French region Centre Registry of Acute Coronary (CRAC) model.

Introduction: In the treatment of ST-segment–elevation myocardial infarction (STEMI), faster times to reperfusion result in better outcomes. Primary prehospital Helicopter Emergency Medical Service (HEMS) interventions may play a role in reperfusion therapy. We analyzed data from our Cardiologic Regional Interventional Observatory Registry involving patients with STEMI aimed at the evaluation of the potential benefit of HEMS interventions as compared with EMS ground transport with MICU (Mobile Intensive care Unit).

Materials and Methods:Retrospective multicentric study conducted from January 2014 to January 2015. All successive patients with STEMI eligible for percutaneous coronary intervention (PCI) were included. Access times were computed allowing the estimation of dispatch French System (SAMU) delay from emergency the phone call to admission to one of the 6 cath labs using standard data collection from the French region Centre Registry of Acute Coronary (CRAC). We analyze pre admission transport time (FMC-DTB) according to  distance between FMC to cath lab location and mode of transport (HEMS vs MICU)

Results: During the study period, 1699 patients with STEMI were included in the Registry.In the overall population, Mean age was 63,2 y-o, sex ratio male was 2,7. The mean time from the emergency phone call to the dispatch center (Number 15 or 112) to the ECG as the First Medical Contact (FMC) is 1h40 mn. Of these patients 82 % were transferred for primary PCI, 2% fibrinolytic therapy, 7% secondary angioplasty.The mean response time FMC to Door-to Balloon (DTB) time was longer using the helicopter HEMS (2h20 mn) than road transport with MICU ambulances (2h:06 min).For short distances (25-74 km) the median delay using road transport was shorter (1h: 54 min) whereas this time by air transport (2h: 12 min).The median transport delay gain was shorter (15 min) for distances over 75 km by using HEMS.

Discussion: In many European countries, patients with STEMI , guidelines have called for device activation within 90 minutes of initial presentation. Our results offer important insights of the impact of transfer time and mode of transport on achievement of guideline goals for D2D time in the treatment of STEMI patients as HEMS transport did not offer D2D time advantages for STEMI patients better than ambulances for short distances. Several explanations: (1) time for air transportation, (2) cases with more complexity (3) distance .In our study for patients with STEMI,  benefits of air transportation with HEMS are not significant for short (< 50 km) or long (> 75 km) distances and may encourage the dispatch center to use the MICU ambulances for a rapid access to PCI .

Conclusions In our CRAC registry for management of STEMI, strategy of decision was associated with longer DTB times with HEMS versus MICU ambulances.Our findings suggest the need for evaluation and continued systems improvement of the use of effective resources for transport of STEMI to the PCI.

 


Eric REVUE (Paris), Christophe SAINT ETIENNE, Pierre MARCOLLET, Stephan CHASSAING, Philippe DEQUENNE, Wael YAFI, Gautier S., Christophe LAURE, Gregoire RANGÉ
15:00 - 16:30 #10949 - OP014 The Clinical epidemiology and prognosis in patients with non-specific chest pain.
OP014 The Clinical epidemiology and prognosis in patients with non-specific chest pain.

 Background

The purpose of this study was to assess the prognosis for patients with suspected acute coronary syndrome (ACS) after the implementation of high sensitivity troponins (hstn). The first objective was to investigate if there had been a change in the incidence of  patients  diagnosed with ischemic heart disease and non-specific chest pain(NSCP) after the implementation of hsTn. The second objective was to determine the mortality in the NSCP group before and after hsTn and the third objective  to evaluate the prognosis and mortality in patients discharged with the diagnosis ACS, stable angina pectoris (SAP), other heart related conditions (OHC) and NSCP after hstn implementation.

 Method

This study is a register based prospective multicentre cohort study. All patients aged 18 and older in the region of southern Denmark with an acute contact to the emergency department or cardiology department in 2013 and who had at least one troponin measurement were included. Depending on their discharge diagnosis and the Troponin value, the patients were stratified into 4 groups, consisting of

a)      Patients with myocardial infarction and elevated Troponin measurement.

b)      Patients with other serious heart disease than ACS

c)      Patients with clinical assessed stable SAP and normal troponin

d)     Patients with normal troponin and without acute heart disease, who were discharged without an explanatory diagnosis of the chest pain, NSCP.

 Patients arewere identified by their troponin measurements from the biochemical system. Endpoint during follow up was obtained from the National Patient Registry and Civil Registration System. Endpoints were readmission with myocardial infarction, ventricular fibrillation/cardiac arrest and all-cause death. Endpoints were reported for one year follow up or until emigration.

 Results

6037 patients were eligible for final analyses. The group consisted of 2 513 patients before and 3 491 after the hstn implementation. Comparing the diagnosis before and after hstn, there was a relative increase in MI of 25% and OHC with 9%, NSCP and SAP decreased with 6% and 43% respectively. The 12 months-mortality for NSCP was 3.4% before hstn and 2% after. No significant difference was shown between in mortality before and after hstn. The prognosis for the four groups after implantation of hstn showed that MI had the highest risk of future MI with 4% event rate during one year. NSCP had 5 times lower risk of future MI compared to the MI group. No significant differences  in mortality was shown when comparing the MI group with the NSCP, OHC or SAP groups.

 Conclusion

The number of NSCP patients decreased after the hstn implementation and had a low risk for future cardiac events No significant differences in mortality was shown comparing the mortality rate in this group before and after hstn implementation. The risk of future MI is significantly lower in NSCP than in the MI group


Nivethitha ILANGKOVAN, Pr Christian Backer MOGENSEN (Aabenraa, Denmark), Axel DIEDERICHSEN, Annmarie LASSEN, Hans MICKLEY
15:00 - 16:30 #10981 - OP015 Anticoagulation at emergency department – can we do better?
OP015 Anticoagulation at emergency department – can we do better?

Background

 

Atrial fibrillation (AF) increases the risk for stroke and other thromboembolic complications. Properly carried out anticoagulation (AC) is the most important treatment for AF patients in stroke prevention, and it has been found to prevent up to 60-70 % of strokes. In clinical practice, the need for anticoagulation in AF is estimated by using CHA2DS2VASc and HAS-BLED scores. CHA2DS2VASc score assesses the thromboembolic risk and HAS-BLED score the risk for bleeding.

According to recent national and international studies, anticoagulation is underused among AF patients. In particular, the Finnish FinFib study showed that as many as 29% of high risk patients did not receive anticoagulation (1). Therefore, we wanted to examine how well the AF treatment is carried out at Tampere University Emergency Department (ED).

 

Materials and methods

 

From 1 October 2014 to 30 November 2014 all patients with AF or atrial flutter (ICD-10 code I48) at ED were identified from hospital records. We collected the following data: age, gender, what type of AC was used and whether the diagnosis was new or previously existing. We also investigated if the CHA2DS2VASc and HAS-BLED scores were calculated during the patients stay. Additionally, we counted both scores for all the patients, regardless of whether they were calculated during the ED visit. For this purpose, we collected data on all patients with any type of risk factors. Finally, we investigated whether the bridge therapy was started with warfarin, and furthermore, what were the INR values of all the patients on warfarin therapy.

 

Results

 

A total of 470 patients with 537 unique ED visits were included in the study. Patients had a mean age of 70 years (range 21 -100 yrs). Out of the unique ED visits, CHA2DS2VASc and HAS-BLED scores were calculated in 19% and 3% of the cases. 87% of all the high-risk and 72% of new high-risk AF patients had AC therapy when leaving the ED. 57% of the patients on warfarin had an INR in therapeutic range (2.0-3.0). Furthermore, only 53% of patients with newly diagnosed AF referred to cardioversion had received bridging AC therapy with small molecular heparin (LMWH).

 

Discussion:

 

We found that although CHA2DS2VASc and HAS-BLED scores were calculated in a minority of the cases, relevant AC therapy for high-risk patients was well executed. However, over every fourth of the high-risk patients with new onset AF did not receive AC therapy when leaving the ED. Furthermore, only half of the patients who began warfarin therapy were prescribed to use bridge therapy with LMWH. Based on these results, we have developed a standardized treatment protocol for AF patients. This protocol includes evaluation of the optimal treatment (rhythm or rate control) and execution of suitable AC treatment for each patient. We have also developed a special program to our ED’s patient data system in which the CHA2DS2VASc and HAS-BLED scores shall be filled in for each patient.


Eveliina PÄIVÄ (Tampere, Finland), Jussi POHJONEN, Hannu PÄIVÄ, Satu-Liisa PAUNIAHO
15:00 - 16:30 #10985 - OP016 Interobserver variability of the HEART score.
OP016 Interobserver variability of the HEART score.

Introduction: The HEART score is a validated risk score for chest pain patients presenting at the Emergency department (ED). The HEART score  consists of five elements; history, ECG, age, risk factors and troponin. All of the elements are scored zero, one or two points, depending on the severity of the abnormality. Two of its elements, history and ECG, are subjective for interpretation by the ED physician. Little is known about the interobserver variability of history and ECG scoring and how this influences the interobserver variability of the final HEART score. The purpose of this study is to assess if the HEART score can be calculated reliably by different physicians.

Methods: For this study data from 125 patients was used. Each patient was scored by two cardiologists, two emergency physicians and two residents. Each physician scored the history and ECG of the 125 cases independently and blinded for the other elements of the HEART score. Interobserver agreement was measured by calculation of the intraclass correlation coefficient (ICC), using R statistics.

Results: Mean HEART score was 4.7 (95% CI 0.7-8.7). The analysis of the separate components yielded an ICC of 0.617 (range 0.0-1.0) for the history and an ICC of 0.512 for the ECG. On top of that, the agreement of the total HEART score between physicians was even higher, with an ICC for the HEART score of 0.888. The ICC for the total HEART score was 0.887 for the cardiologists, 0.882 for the emergency physicians and 0.986 for the residents.

Conclusion:  This study shows a very high ICC between different physicians at the ED, demonstrating a very high interobserver reliability of the HEART score. This supports the use of the HEART score by  several physicians. 


Simone GOPAL, Barbra BACKUS (Rotterdam, The Netherlands), Hans KELDER, Ron KUSTERS
15:00 - 16:30 #11058 - OP017 The randomized controlled trial: Comparison of success rate of standard and modified valsalva maneuvers to terminate supraventricular tachycardia.
OP017 The randomized controlled trial: Comparison of success rate of standard and modified valsalva maneuvers to terminate supraventricular tachycardia.

Abstract

Purpose: The purpose of the study is to detect whether using modified valsalva maneuver (VM) be more effective than standard VM in terminating SVT. 

Material and Method:This prospective randomized control trial, was conducted in an emergency department with patients who diagnosed SVT between 01.12.2015 - 31.12.2016. Participants were divided into two groups, randomly as standard VM or modified VM, as the first treatment with two-dimensional permutation blocks; in the order of arrival of the patients. The randomization was performed by envelope method. In both groups; the determined procedure for standard or modified VM were repeated up to three times in unresponsive patients. In both groups; if the maneuver is unsuccessful after three attempts, rescue medication with anti-arrhythmic treatment used. The primary outcome was defined to compare the success rate of achieving sinus rhythm after standard VM and modified VM.

Results: Totally, 56 patients were included randomly to this study; 28 were assigned to the standard VM, and 28 were assigned to the modified VM. Three of 28 patients(10.7%) in VM group and 12 of 28 patients(42.9%) in modified VM group were returned to sinus rhythm after intervention (p=0.007). Number of patients who need rescue treatment was lower in modified VM group, 16 (57.1 %) of 28, than in standard VM group, 25 (89.3%) of 28 (p=0.007).

Conclusion: Modified VM therapy is more effective than standard VM for terminating of SVT. It also indirectly reduces the need for anti-arrhythmic medication and indirectly causes fewer side effects. Therefore, we believe that modified VM can be considered as a first line treatment option in management of SVT according to results of this and previously studies. 


Seref Kerem CORBACIOGLU, Emine EMEKTAR, Yunsur CEVIK, Halit AYTAR (Ankara, Turkey), Mehmet Veysel ONCUL, Sedat AKKAN, Huseyin UZUNOSMAOGLU
15:00 - 16:30 #11619 - OP018 Multicentre, prospective validation of the Troponin-only Manchester Acute Coronary Syndromes decision aid using a single point of care troponin test in the Emergency Department.
OP018 Multicentre, prospective validation of the Troponin-only Manchester Acute Coronary Syndromes decision aid using a single point of care troponin test in the Emergency Department.

Background

Chest pain is the most common reason for emergency hospital admission, although the majority could be avoided with improved diagnostic technology. The Troponin-only Manchester Acute Coronary Syndromes (T-MACS) decision aid ‘rules in’ and ‘rules out’ acute myocardial infarction (AMI) with one blood test at the time of arrival in the Emergency Department (ED). T-MACS estimates the probability of AMI using basic data about a patient’s symptoms, signs, electrocardiogram and a single concentration of high sensitivity cardiac troponin (hs-cTn), a central laboratory assay.

Successful validation with a point of care (POC) cardiac troponin (cTn) assay would reduce turnaround time, helping to unburden crowded EDs. We aimed to prospectively validate T-MACS with a contemporary POC cTn assay.

Methods 

In this multi-centre prospective diagnostic accuracy study nested within the Bedside Evaluation of Sensitive Troponin (BEST) programme, we recruited patients with suspected cardiac chest pain presenting to nine EDs. Patients with another medical condition requiring hospital admission and those whose symptoms peaked >12h ago were excluded. Ethical approval was obtained and all participants provided written informed consent. 

Blood samples drawn on arrival were analysed for cTnI using the POC i-Stat assay (Abbott Point of Care, New Jersey, 99th percentile 80ng/L, LoD 20ng/L). The primary outcome was a diagnosis of AMI, which was defined in accordance with the Third Universal Definition based on central laboratory cTn analysis. To provide an adequate reference standard, the protocol required that all patients also undergo serial central laboratory cTn testing over at least 3 hours (for high sensitivity assays) or at least 6 hours (contemporary assays). 

T-MACS was computed using the original reported formula. We calculated sensitivity, specificity, positive and negative predictive values and positive and negative likelihood ratios.

Results 

A total of 622 patients were included in this analysis, of which 78 (12.5%) had AMI. Key results are summarised in Table 1. With a single POC cTn test, T-MACS would have ‘ruled out’ 41.6% (n=259) patients with a sensitivity of 97.4% (95% CI 91.0–99.7%) and a negative predictive value of 99.2% (95% CI 97.0–99.8%). Two AMIs were missed based on serial laboratory cTn concentrations. One patient did not receive a clinical diagnosis of AMI, received no treatment, did not undergo further investigation and had no adverse events within 30 days.

T-MACS would have ‘ruled in’ 7.1% (n=44) patients with a specificity of 99.2% (95% CI 98.0–99.8%) and a positive predictive value of 90.9% (95% CI 78.5–96.5%).

Conclusions

To our knowledge this is the first successful validation of a single test ‘rule out strategy’ using a POC cTn assay. Its use could enable almost immediate reassurance and discharge for >40% of patients with suspected cardiac chest pain.


Pr Richard BODY (Manchester, ), Malak AL MASHALI, Sarah DOUGLAS, Garry MCDOWELL
Kokkali
16:40

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A13
16:40 - 18:10

Education (Cutting Edge) decision making
How to help our Stone Age minds to make good decisions?

Moderators: Eric DRYVER (Consultant) (Lund, Sweden), Senad TABAKOVIC (Medical director emergency department) (Zürich, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
16:40 - 18:10 Creating evidence to improve safety and effectiveness of ED patient care. Ian STIELL (Physician) (Speaker, Ottawa, Canada)
16:40 - 18:10 Decision-making through the lense of quantum physics. Eric DRYVER (Consultant) (Speaker, Lund, Sweden)
16:40 - 18:10 Can big data replace gut feeling? Catherine CHRONAKI (Secretary General) (Speaker, Brussels, Belgium)
Trianti Hall

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B13
16:40 - 18:10

Thrombosis (How To)

Moderators: Pr Cem OKTAY (FACULTY) (ANTALYA, Turkey), Karim TAZAROURTE (Chef de service) (Lyon, France)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
16:40 - 18:10 Update on the management of anticoagulant-related bleeding. Anil CHOPRA (Speaker, Canada)
16:40 - 18:10 Cutting edge controversies in the management of pulmonary embolism. Anil CHOPRA (Speaker, Canada)
16:40 - 18:10 Ultrasound and venous thromboembolism. Eleni SALAKIDOU (Delegate) (Speaker, Heraklion, Greece)
Mitropoulos

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C13
16:40 - 18:10

Trauma (Game Changers)

Moderators: Silvia BRESSAN (Moderator) (Padova, Italy), Karim TAZAROURTE (Chef de service) (Lyon, France)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
16:40 - 18:10 Challenges in managing head injuries in patients who are anticoagulated. Pr Suzanne MASON (Professor of Emergency Medicine) (Speaker, Sheffield, United Kingdom)
16:40 - 18:10 Top ten trauma papers. Judith TINTINALLI (Professor) (Speaker, Chapel Hill NC, USA)
16:40 - 18:10 It's the end of the world as we know it: should we stop immobilizing all trauma patients? Demetrios PYRROS (Speaker, Greece)
Banqueting Hall

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D13
16:40 - 18:10

YEMD - Toxicology
Drugs & Alcohol

Moderators: Martin FANDLER (Consultant) (Bamberg, Germany, Germany), Dr Pieter Jan VAN ASBROECK (Consultant in Emergency Medicine) (Genk, Belgium)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
16:40 - 18:10 Chemical warfare and terrorism. Bulut DEMIREL (Clinical Development Fellow) (Speaker, Glasgow)
16:40 - 18:10 Toxic ECGs. Dr Pieter Jan VAN ASBROECK (Consultant in Emergency Medicine) (Speaker, Genk, Belgium)
16:40 - 18:10 Emergency Sedation of the agitated intoxicated patient. Martin FANDLER (Consultant) (Speaker, Bamberg, Germany, Germany)
Skalkotas

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E13
16:40 - 18:10

Disaster Medicine II - (Game changers)

Moderators: Vitor Manuel LOPES FERNANDES ALMEIDA (doctor) (viseu, Portugal), Benoît VIVIEN (Adjoint du Chef de Service du SAMU de Paris, Responsable du SAMU Pédiatrique Régional IDF) (Paris, France)
Coordinator: Dr Abdo KHOURY (Coordinator, Besançon, France)
16:40 - 18:10 Humanitarian opportunities for young doctors. Luca RAGAZZONI (Scientific Coordinator) (Speaker, Novara, Italy)
16:40 - 18:10 Triage in MCI: still needed? Benoît VIVIEN (Adjoint du Chef de Service du SAMU de Paris, Responsable du SAMU Pédiatrique Régional IDF) (Speaker, Paris, France)
16:40 - 18:10 Education in disaster medicine: the TDMT experience. Marta CAVIGLIA (PhD Candidate) (Speaker, Novara, Italy)
MC-3

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F13
16:40 - 18:10

Free Papers Session 3

Moderators: Dr Thomas BEATTIE (Senior lecturer) (Edinburgh, United Kingdom), Mohammad Ashraf BUTT (Consultant in Emergency Medicine) (Cavan, Ireland)
16:40 - 18:10 #11025 - OP020 Clinical decision rule to improve the adequacy of CT scan for syncope in the emergency department.
OP020 Clinical decision rule to improve the adequacy of CT scan for syncope in the emergency department.

BACKGROUND: In the last two decades we have observed a dramatically increase of the CT scans use at the emergency department (ED). As a result, there has been growing concern around the increase of medical radiation exposure and cancer. The positive rate of head CT in non-trauma patients presenting to the ED is low. Currently, indications for imaging are based on the individual experience of the emergency physician, which contributes to overuse and variability in imaging indication. In adult patients with syncope, without cranioencephalic trauma and with no alarm signs, there is variability and inadequacy in deciding to request a CT scan. The aim of this study is to ascertain the predictors of a positive head CT scan in patients with syncope and demonstrate the feasibility of clinical decision rule (CDR) to improve the adequacy.

METHODS: A systematic search for evidence was made based on a PICO question (Haynes pyramid). After the search PubMed and Embase (2005-2014) was consulted. Four reviewers reviewed all citations and select eligible ones for inclusion. Two authors independently appraised the quality of the studies and their degree of recommendation (GRADE). All disagreements among reviewers were discussed and resolved by a third independent reviewer. After the systematic review CDR was developed and included in the Electronic Clinical Record System at the Emergency department. We retro/prospectively reviewed all ED syncope patients 6 months before and after implementing the CDR. Medical records were assessed for analyzing the adequacy of the CDR and a telephone call was made after 30 days from discharge, in order to ensure that a related event had not occurred.

REUSLTS: The CDR has 5 items (alarm signs) and if any of them was present the CT scan should be performed. The items were: abrupt/severe headache after vigorous exercise, neurological focus, alteration of the level of consciousness, meningism and hypertension emergency. Both in the pre and post-implantation groups, 10% of the syncope had alarm signs. From patients with alarm signs, 10% had a positive CT result. In the cases that did not show alarm signs (90%) an evident differentiation was detected resulting in the Pre-CDR group being 46% unsuitable indications, compared to 7.6% after the CDR implantation, which shows that the goal of adapting CT indications was achieved. None of the patients that were discharged from the emergency department without a CT scan had a new event related with the syncope (CDR had a safety of 100%). Finally, a cost analysis was carried out. We found a reduction of total expenditure of CT scan from 50% to 20% post-intervention, which accounts a total of 85,848 euros savings annually.

DISCUSSION: We can conclude that, the implementation of the CDR for the indication of a CT scan, being the reason of the consultation the syncope at the emergency department, is safe and increases the adequacy reducing not only the costs but also the medical radiation exposure.


Aitor GARCÍA DE VICUÑA, Eunate ARANA-ARRI (Berango, Spain), Ana SANTORCUATO, Sara DE BENITO, Rafael VILLORIA, Jennifer BARREDO, Josu MENDIOLA, Iraide EXPOSITO, Iñaki GUTIERREZ-IBARLUZEA
16:40 - 18:10 #11622 - OP021 Predicting good outcome after in-hospital cardiac arrest -validation of the GO-FAR score.
OP021 Predicting good outcome after in-hospital cardiac arrest -validation of the GO-FAR score.

Background

Approximately 2300 in-hospital cardiac arrests (IHCA) occur annually in Sweden and the prognosis for those affected is poor with 29% survival to hospital discharge. A do-not-attempt-resuscitation (DNAR) order is issued when it is against the wishes of the patient that cardiopulmonary resuscitation (CPR) is performed, or when CPR is considered medically futile; that is when the chances of good quality survival are minimal. Emergency physicians are required to address the question of futility in the emergency department, but scientific support to fulfill this task is sparse. The Good Outcome Following Attempted Resuscitation (GO-FAR) score was developed in 2013 and has not been validated on a population basis outside the index population. The GO-FAR score is a summed score consisting of 13 prearrest variables with values ranging from -15 to 11 points reflecting the likelihood of good neurological survival at discharge measured as CPC 1 (patient is alert, able to work and lead a normal life, may have minor psychologic or neurologic deficits). A prearrest prediction tool for good outcome after IHCA would substantially contribute to daily clinical practice and reduce barriers for discussing DNAR orders. 

Methods

This validation study is based on a retrospective cohort of adult IHCA in Stockholm County 2013 to 2014 identified through the Swedish Cardiopulmonary Resuscitation Registry (SCRR). SCRR provides patient and event characteristics, personal identification numbers and CPC score at discharge. Data for the GO-FAR variables was obtained from manual review of hospital electronic patient records. The model performance was evaluated by quantifying discrimination and calibration, calculating the area under the receiver operating curve (AUROC) and evaluating the calibration plot with calibration-in-the-large and calibration slope.

Results

The final cohort included 717 patients with a 30-day survival of 27.5% and survival with good outcome at discharge of 22.3%. 61.9% were male, mean age was 72 years (SD 14 years) and 22.1% presented with ventricular fibrillation or ventricular tachycardia. In complete case analysis (526 cases) AUROC was 0.82 (95% CI 0.78 to 0.86) indicating good discrimination. The calibration slope was 1.38 (95% CI 1.08 to 1.68) and calibration-in-the-large -0.84 (95% CI -1.05 to -0.63) indicating that the GO-FAR score systematically underestimates the probability of good neurological survival.

Conclusion

The GO-FAR score shows satisfactory discrimination but dissatisfactory calibration in a cohort representing a Swedish population. It has the ability to distinguish a patient with good outcome from a patient with adverse outcome, but good outcome is systematically underestimated. Recalibration of the GO-FAR score is suggested before taken into clinical practice in Sweden.


Eva PISCATOR (Stockholm, Sweden), Samuel BRUCHFELD, Ulf HAMMAR, Sara EL GHARBI, Katarina GÖRANSSON, Johan HERLITZ, Mark EBELL, Therese DJÄRV
16:40 - 18:10 #11722 - OP021b The Copenhagen Triage Algorithm is superior to a traditional triage algorithm - A cluster-randomized study.
OP021b The Copenhagen Triage Algorithm is superior to a traditional triage algorithm - A cluster-randomized study.

Background

Triage systems have been implemented in most emergency departments (EDs) worldwide to minimize crowding and treatment delays that may adversely affect outcomes in acutely admitted patients. Triage systems are designed firstly to identify patients in need of immediate care, and second to provide risk stratification and ensure the optimal distribution of resources.

However, pre-existing triage systems are time consuming, supported by limited evidence, and could potentially be of more harmful than beneficial.

This trial prospectively compared a new simplified triage system with emphasis on clinical judgement with a traditional triage system with focus on clinical endpoints.

Methods

The Copenhagen Triage Algorithm (CTA) study was a large prospective, two-center, cluster-randomized, parallel, cross-over, open trial comparing CTA to a traditional triage system, Danish Emergency Process Triage (DEPT), which is a local adaptation of the internationally used ADAPT system.

All patients ≥17 years admitted to the ED in two large hospitals in a 10-month period were randomly cluster allocated to either CTA or DEPT triage with subsequent crossover. Based on vital signs and a subsequent clinical assessment by the ED nurse, CTA stratifies patients into 5 acuity levels. 

The study had a non-inferiority design with 30-day all-cause mortality as the primary endpoint. The non-inferiority margin was set at 0.5%. As a secondary endpoint, the study aimed to assess if CTA was superior in predicting 30-day mortality as assessed by C-statistics.

Results

A total of 45,977 patient visits were included. Of these 23,415 (50.9%) visits were triaged using CTA and 22,562 (49.1%) visits using DEPT.  Patients were well matched on baseline characteristics. The non-inferiority criteria was met, with the 30-day mortality among patients triaged with CTA and DEPT at 3.35% and 3.28%, respectively (p=0.68), a difference of 0.07% (95% CI: -0.26-0.40). Comparable results were observed for mortality at 48 hours (0.63% and 0.68%, p=0.58 using CTA and DEPT, respectively) and at 90 days (6.18 % and 6.36 %, p=0.41 using CTA and DEPT, respectively).

The triage level of patients in the CTA group was significantly lower (P<0.001) and CTA was superior in predicting 30-day mortality with an AUC of 0.670 (95% CI 0.650-0.690) compared to 0.638 for DEPT (95% CI 0.618-0.659) (P=0.03). Still there was no significant increase in mortality among low risk patients. A sensitivity analysis including vital signs, age, and sex showed no added risk among patients in the CTA arm for mortality at 48 hours (HR 1.07, 95% CI 0.97-1.18), 7 days (HR 0.98, 95% CI. 0.98-0.99), 30 days (HR 0.98, 95% CI 0.89-1.08) or 90 days (HR 1.03, 95% CI 0.96-1.1).

Conclusion

A new triage system based on vital signs and a clinical assessment by an ED nurse was non-inferior to a traditional triage algorithm with regards to mortality and superior at predicting 30-day mortality. 


Rasmus Bo HASSELBALCH, Mia PRIES-HEJE, Martin SCHULTZ (Copenhagen, Denmark), Louis LIND PLESNER, Lisbet RAVN, Morten LIND, Rasmus GREIBE, Birgitte NYBO JENSEN, Thomas HØI-HANSEN, Nicholas CARLSON, Christian TORP-PEDERSEN, Lars S. RASMUSSEN, Kasper IVERSEN
16:40 - 18:10 #10536 - OP022 Straddle compared with conventional chest compressions in manikin model.
OP022 Straddle compared with conventional chest compressions in manikin model.

Terapat Chantawong*, Pilaiwan Sawangwong*, Warawut Khangmak*, Chaiyaporn Yuksen MD,  Yuwares Sittichanbuncha ,MD. Department of Emergency Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

 Backgrounds: Out of hospital cardiac arrest (OHCA) is one of the main causes of death in Thailand. Chest compression in narrow space may occur in ambulance or aircraft. Straddle chest compression is one of the technique to help the stability of chest compression.

Objective:  To compare the quality of chest compressions and exhaustion of healthcare provider between straddle chest compression and conventional chest compression in manikin model.

Methodology: This is an experimental study randomization into two different group, by using the SNOSE and block of four randomization by dividing them into group A (Straddle chest compression) and group B (conventional chest compression). Each participants were performed maximum 4 minutes hands only compression, quality parameters were recorded: compression rate and depth. The blood pressure, heart rate and respiratory rate of each participant were recorded both before and after chest compression.

Result: 124 participants (mean age 25.8 years and 27.6 percent are male, 40), the rate of chest compressions in conventional CPR and straddle CPR (126.2±17.1 and 127.0±21.0, p = 0.811), the average depth (43.8±9.6) and 43.4±9.0), p = 0.830). The blood pressure, heart rate and respiratory rate before and after chest compression in both method was no clinical significantly. 
  
Conclusion: The quality of straddle chest compression was as good as conventional chest compression. The exhaustion of healthcare provider between Straddle and conventional chest compression was no clinical significantly.


Terapat CHANTAWONG, Chaiyaporn YUKSEN, Terapat CHANTAWONG (Bangkok, Thailand)
16:40 - 18:10 #10592 - OP023 Traumatic cardiac arrest in Sweden 1990-2015 - a population-based national cohort study.
OP023 Traumatic cardiac arrest in Sweden 1990-2015 - a population-based national cohort study.

Background: Trauma is a main cause of death among young adults worldwide. Patients experiencing a traumatic cardiac arrest (TCA) certainly have poor prognosis but population-based studies are sparse.

Aim: Primarily to describe characteristics and 30-day survival following a TCA as compared with a medical out-of-hospital cardiac arrest (medical CA).

 Material and methods: A cohort study based on data from the nationwide, prospective population-based Swedish Registry for Cardiopulmonary Resuscitation (SRCR) between 1990 -2015. The definition of  a TCA in the SRCR is, a patient who is unresponsive with apnoea where cardiopulmonary resuscitation and/or defibrillation have been initiated and in whom the Emergency Medical Services (EMS) reported trauma as the aetiology. Outcome was overall 30-day survival. Descriptive statistics as well as multivariable logistic regression models were used.

Results: In all, between 1990-2015, 1 710 (2,4%) cases had a TCA and 69 123 had a medical CA. Overall 30-day survival gradually increased over the years and was in total among TCAs 3,8% compared to 8.0% following a medical CA (p<0.01). Factors associated with a higher 30-day survival were bystander witnessed TCA and having a shockable initial rhythm (adjusted OR 2.65, 95% C.I. 1.13–6.21 and OR 9.38 (4.44-19.85, respectively) while those given adrenaline had a poorer survival (adjusted OR 0.40, 95% C.I. 0.19 - 0.83).

 Conclusion: Even if the prevalence of TCAs is low and survival is poorer than in medical CAs, many affected individuals are young. Therefore, resuscitation in TCAs should not be seen as futile, but rather an area considered for improvements.  


Therese DJARV (Stockholm, Sweden)
16:40 - 18:10 #11103 - OP024 Outcome Determinants in Pediatric Out of Hospital Cardiac Arrests Post 2010.
OP024 Outcome Determinants in Pediatric Out of Hospital Cardiac Arrests Post 2010.

Objective:

To determine which factors had the most impact on outcomes after pediatric out-of-hospital cardiac arrest (POHCA) now that protocol guidelines have become more aligned with those for adults, including emphasis on quality CPR.

Methods:

In an EMS jurisdiction using a comprehensive Utstein-style database, all POHCA cases over the previous 5 calendar years (1/1/12 through 12/31/16) -- since implementation of the latest international guidelines -- were analyzed to identify current predictors for return of spontaneous circulation (ROSC), hospital admission (HA) and survival to successful hospital discharge (SURV). Logistic regression models of traditional predictors were performed using JMP 12.0 for Mac.

 

Results:

Of 133 consecutive POCHA cases studied (61 % male), the interquartile range (IQR) for response intervals was 16 to 47 minutes (range: 0-490). As traditionally predicted, shorter times from arrest to EMS arrival were associated significantly with ROSC, HA and SURV (all p<0.0001) whereas witnessed arrest cases (only 13%) were not (p=NS). Still, in 95% of cases, the arrest was identified by a bystander prior to EMS arrival and, contrary to previous studies, chest compressions were performed by bystanders in 59% of cases. While the earlier CPR was provided by EMS personnel was itself significantly associated with ROSC, HA and SURV (all P<0.0001), some form of treatment before EMS arrival was provided in 54% of cases and such actions were strongly associated with ROSC, HA and SURV (p<0.0001 for all) whereas AED placement (50% of cases) was not.

  

Conclusion:

Whereas witnessed arrests and AED placement were not identified as contributing factors in this subpopulation of arrests, 1) shorter elapsed intervals from the moment of arrest to EMS arrival, 2) performance of CPR prior to EMS arrival and, in fact, 3) any treatment provided before EMS arrival, resulted in significantly higher rates of ROSC, hospital admission and survival beyond hospital discharge.


Paul BANERJEE (Orlando, USA), Paul PEPE, Amninder SINGH, Latha GANTI
16:40 - 18:10 #11196 - OP025 Evolution of the survival of non-traumatic out-of-hospital cardiac arrests due to ventricular fibrillations over a 10 years’ period.
OP025 Evolution of the survival of non-traumatic out-of-hospital cardiac arrests due to ventricular fibrillations over a 10 years’ period.

Goal: The aim of this study was to assess the survival of victims of out-of-hospital cardiac arrests due to ventricular fibrillations of three successive cohorts over a 10 years’ period.

Materials and methods: This was a retrospective observational study that compared three successive cohorts. The study was approved by an ethics committee. Inclusion criteria were: non-traumatic out-of-hospital cardiac arrests due to ventricular fibrillations shocked by an automated external defibrillator, and having benefited from prehospital advanced life support by a team managed by an emergency physician. Collected variables were: the period of occurrence of the cardiac arrest (1st period = P1 - September 2005 to March 2007, 2nd period = P2 - June 2011 to December 2012, 3rd period = P3 - June 2014 to December 2015), the patient’s age and gender, the location of the cardiac arrest, the presence of a witness, the initiation of chest compressions by a bystander, the number of external electric shocks delivered by the automated external defibrillator, and the number of adrenaline injections administered by the advanced life support team. The primary endpoint was the hospital discharge. The secondary endpoint was the admission to the hospital with a palpable pulse. We used a logistic regression model to estimate the relationship between hospital discharge and the variables that were collected. We show the median [interquartile range] or the rate (%) according to the quantitative or qualitative nature of variables.

Results: A total of 2,648 patients (843 for P1, 830 for P2, 975 for P3) were included (62 years-old [51–74]; 1,608 (60.7%) men). Patients admitted to the hospital with a pulse during P1, P2, P3 were respectively 361 (43%), 464 (56%), 555 (57%) (p < 0.001). Patients discharged from the hospital during P1, P2, P3 were respectively 101 (12%), 166 (20%), 204 (22%) (p <0.001). In the multivariate analysis, factors associated with hospital discharge were: being a woman, a younger age, the occurrence of the cardiac arrest in a public area, and chest compressions by a witness. The rate of witnesses who performed chest compressions increased considerably over time (28% of cases for P1, 50% for P2, and 67% for P3). Adjusted odds-ratio associated with hospital admission were respectively: 1 for P1, 2.3 [1.8–3.0] for P2, and 1.8 [1.4–2.3] for P3.

Discussion: The survival of out-of-hospital cardiac arrests due to ventricular fibrillations shocked by an automated external defibrillator has improved over the past ten years. The increase of the rate of victims who benefited from chest compressions provided by a witness is one of the explanatory factors.

Conclusion: Efforts undertaken to improve the chain of survival, especially the early recognition of out-of-hospital cardiac arrests, an early cardiopulmonary resuscitation, and an early defibrillation must be continued.


Romain KEDZIEREWICZ (Brignoles), Daniel JOST, Guillaume JOLY, Wulfran BOUGOUIN, Eloi MARIJON, Florence DUMAS, Alain CARIOU, Michel BIGAND, Xavier JOUVEN, Jean-Pierre TOURTIER
16:40 - 18:10 #11200 - OP026 Factors associated with the recurrence of ventricular fibrillations in the case of out-of-hospital cardiac arrests - preliminary results of a retrospective observational study.
OP026 Factors associated with the recurrence of ventricular fibrillations in the case of out-of-hospital cardiac arrests - preliminary results of a retrospective observational study.

Background: In the case of out-of-hospital cardiac arrests, 50% of ventricular fibrillations reoccur at least one time, mainly after the resumption of chest compressions. The aim of this study was to identify factors associated with the time between the resumption of chest compressions and the recurrence of the ventricular fibrillation (“CC-VF”). 

Materials and methods: We conducted a retrospective observational study. Collected variables were: patients’ age and gender, the presumed origin of the cardiac arrest, its location, the presence of a witness, the initiation of chest compressions by a bystander. We extracted from automated external defibrillators the rate of chest compressions, the time and length of each chest compressions’ interruption, the time between external electric shocks and the resumption of chest compressions (“EES-CC”), and “CC-VF”. Inclusion criteria were: out-of-hospital cardiac arrests, being over 18 years-old, one or more recurrences of a ventricular fibrillation shocked by an automated external defibrillator of basic life support teams. We performed a univariate analysis followed by a multinomial regression on repeating data; only variables associated with “CC-VF” with p < 0.2 in the univariate analysis were included in the multivariate analysis. We show the median [interquartile range] or the rate (%) according to the quantitative or qualitative nature of variables.

Results: Between 2010 and 2013, we recruited 266 patients (62 years-old [51.5–76]; 212 (80%) men) for a total of 1,047 episodes of recurrent ventricular fibrillations. A witness was present in 129 (48%) cases and performed chest compressions in 57 (21%) cases. The number of external electric shocks by automated external defibrillator ranged from 1 to 19. Concerning recurrences of ventricular fibrillations, 342 (32.7%) episodes occurred before the resumption of chest compressions, 129 (12.3%) were concomitant of the resumption of chest compressions, 170 (16.2%) occurred between 2.5 and 10 s after the resumption of chest compressions, and 406 occurred more than 10 s after the resumption of chest compressions. In the univariate analysis, factors associated with a shorter “CC-VF” were: being a male, an older age, a presumed cardiac origin of the cardiac arrest, the presence of a witness, a longer “EES-CC”, faster chest compressions’ rates, and greater chest compressions’ ratios. In the multivariate analysis, an older age and a faster rate of chest compressions were associated with a shorter “CC-VF”. A longer time between the first alert to the dispatch center and the initiation of chest compressions was associated with a longer “CC-VF”.

Discussion: This is the first study to identify factors associated with the time between the resumption of chest compressions and the recurrence of a ventricular fibrillation. If preliminary results presented above are confirmed, new approaches could be suggested to deal with the recurrence of ventricular fibrillations.


Romain KEDZIEREWICZ (Brignoles), Daniel JOST, Vivien HONG TUAN HA, Julie TRICHEREAU, Pascal DANG MINH, Sarah MENETRE, Vincent THOMAS, Jean-Pierre TOURTIER
16:40 - 18:10 #11605 - OP027 Variations in occurrence of out-of-hospital cardiac arrest in time in the Czech and Slovak republics.
OP027 Variations in occurrence of out-of-hospital cardiac arrest in time in the Czech and Slovak republics.

Background: Circadian variation in occurrence of out-of-hospital cardiac arrest (OHCA) is an observation which has been reported from several parts of the world. Mostly, diurnal variation was shown exhibiting low incidence of OHCA at night and a two daytime peaks, in the morning and late afternoon. However, this variation can be related to geographical regions and the validity of the results is extremely dependent on the quality of the data collection. Therefore we have analyzed the Czech and Slovak data from the EuReCa ONE study to investigate whether there is any local significant variation of OCHA events treated by Emergency Medical Services (EMS) in time and if so, whether it depends on geographic variables.

Methods: In an international clinical study EuReCa ONE (European Registry of Cardiac Arrest), data on all EMS treated OHCA events were collected from the entire territory of the Slovak Republic (5421352 inhabitants) and several administrative regions of the Czech Republic (4350000 inhabitants) in the period from 1.10.2014 to 31.10.2014. Data were processed and analyzed for circadian and infradian variability.

Results: For the selected period, a total of 659 cases of confirmed resuscitated OHCA events was reported. Significant circadian variation was observed, with very low occurrence in the night (approximately 2% of all episodes each hour) followed by three peaks in the daytime, in the 9th, 16th and 20th hour (8.2, 6.4 and 7.4 % of all episodes, respectively, p<0.05). During the week, OHCA events were the most frequent on Fridays while the least common on Tuesdays (16.8 versus 12.1 % of all events, p=0.019). In the Czech Republic, OHCA was more frequent at weekends than in Slovakia (31.2 versus 22.4 % of all episodes, p=0.013). The lowest thirty-day survival or survival to hospital discharge was observed in OHCA events that occurred on Tuesdays, while highest in episodes that occurred on Thursdays (6.2 versus 20.6 %, p=0.011). Time dependent variation of survival patterns were We did not found any differences between the Czech and Slovak republics in survival variation.

Discussion: In the selected regions and time interval we have identified a marked circadian and infradian variability of OHCA events occurrence and of their survival as well. While the variability of the events in time was partly country-dependent, survival was not. Further investigation of this phenomenon may lead to a better understanding of the circumstances leading to cardiac arrest and improve prevention of this cardiovascular catastrophe.

References: Gräsner JT et al. EuReCa ONE-27 Nations, ONE Europe, ONE Registry: Aprospective one month analysis of out-of-hospital cardiac arrest outcomes in 27 countries in Europe. Resuscitation 2016;105:188-95.


Skulec ROMAN (Kladno, Czech Republic), Trenkler STEFAN, Dobias VILIAM, Franek ONDREJ, Havlikova EVA, Knor JIRI, Mokrejs PETR, Smrzova EVA, Svitak ROMAN, Truhlar ANATOLIJ, Grasner JAN-THORSTEN
Kokkali
18:15

"Sunday 24 September"

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A14
18:15 - 19:00

EUSEM 2017 Opening Ceremony

18:15 - 19:00 Welcome Addresses. Roberta PETRINO (Head of department) (Keynote Speaker, Italie, Italy), Panos AGOURIDAKIS (Keynote Speaker, IRAKLION, Greece), Christoph DODT (Head of the Department) (Keynote Speaker, München, Germany)
18:15 - 19:00 Official Opening of the Congress.
Dr Andreas XANTHOS, Minister of Health & Social Welfare of Greece
18:15 - 19:00 Opening Lecture with Narration Traumatic Injuries in Homer’s Iliad.
The Emergence of Emergency Medicine in Greek Antiquity? Helen ASKITOPOULOU, on behalf of HeSEM
Nantia SPILIOTOPOULOU, narration of Homer’s verses
18:15 - 19:00 Recital - Songs from Greece & the Mediterranean.
Savina YANNATOU, voice & Kostas GRIGOREAS, classical guitar
Trianti Hall
Monday 25 September
08:30

"Monday 25 September"

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A20
08:30 - 09:00

Keynote Lecture 1

Moderator: Senad TABAKOVIC (Medical director emergency department) (Zürich, Switzerland)
08:30 - 09:00 Pitfalls in the management of older patients. Pr Christian NICKEL (Vice Chair ED Basel) (Speaker, Basel, Switzerland)
Trianti Hall
09:00

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SIM CUP
09:00 - 17:30

SIM CUP

Coordinators: Guillem Bouilleau (France), François Lecomte (France), Youri Yordanov (France)
Faculty: Cindy Bouzin (France), Lucie Desmond (France), Mohamed El Ouali (France), Sébastien Faucher (France), Christelle Hermand ( France), Laura Ribardière (France), Lucie Marchais (France)
Jury: Pier Luigi Ingrassia (Italy), Felix Lorang (Germany), Mohamed Mouhaoui, Carl Ogereau (France)
Foyer Skalkotas
09:10

"Monday 25 September"

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A21
09:10 - 10:40

Pre-hospital (Cutting Edge)

Moderators: Pr Christian NICKEL (Vice Chair ED Basel) (Basel, Switzerland), Dr Jana SEBLOVA (Emergency Physician) (PRAGUE, Czech Republic)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
09:10 - 09:40 OHCA: Only the dispatcher can save lives!? Ondrej FRANEK (Speaker, Czech Republic)
09:40 - 10:10 Air support - Helicopter intervention in special situations. Carmen Diana CIMPOESU (Prof. Head of ED) (Speaker, IASI, Romania)
10:10 - 10:40 Airway Mangement - prehospital life-hacks you definitely need to know! Christian HOHENSTEIN (PHYSICIAN) (Speaker, BAD BERKA, Germany)
Trianti Hall

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B21
09:10 - 10:40

Digitalisation in the ED
"Rage against the machine, the digital revolution in the ED"

Moderators: Catherine CHRONAKI (Secretary General) (Brussels, Belgium), Tiziana MARGARIA STEFFEN (Ireland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
09:10 - 09:40 Digitalisation in the ED, the role of patient summary. Catherine CHRONAKI (Secretary General) (Speaker, Brussels, Belgium)
09:40 - 10:10 Digitalised health departments as part of a digitalised health community. Simon DE LUSIGNAN (EUSEM 2017) (Speaker, Guildford, United Kingdom)
10:10 - 10:40 Panel discussion. Roberta PETRINO (Head of department) (Speaker, Italie, Italy), Catherine CHRONAKI (Secretary General) (Speaker, Brussels, Belgium), Simon DE LUSIGNAN (EUSEM 2017) (Speaker, Guildford, United Kingdom), Tiziana MARGARIA STEFFEN (Speaker, Ireland)
Mitropoulos

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C21
09:10 - 10:40

Geriatric (Game Changers)

Moderators: Pr Abdelouahab BELLOU (Director of Institute) (Guangzhou, China), Simon. P. MOOIJAART (Internist-geriatrician) (LEIDEN, The Netherlands)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
09:10 - 09:40 Evidence-based medicine in older patients: why and how is it different from what you know. Simon. P. MOOIJAART (Internist-geriatrician) (Speaker, LEIDEN, The Netherlands)
09:40 - 10:10 Approach to the acutely presenting older patient. Jacinta A. LUCKE (Emergency Phycisian) (Speaker, Haarlem, The Netherlands)
10:10 - 10:40 Geriatric Emergency Medicine – our new bread and butter. Pr Suzanne MASON (Professor of Emergency Medicine) (Speaker, Sheffield, United Kingdom)
Banqueting Hall

"Monday 25 September"

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D21
09:10 - 10:40

YEMD - Violence in the ED

Moderators: Dr Monika BRODMANN MAEDER (Senior Consultant, Head of Education and Mountain Emergency Medicine) (Bern, Switzerland), Basak YILMAZ (Faculty) (BURDUR, Turkey)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
09:10 - 09:30 The Hague Protocol: 'A succesful method for detecting Child Maltreatment at the Emergency Department'. Hester DIDERICH-LOLKES DE BEER (policy officer family maltreatment) (Speaker, THE HAGUE, The Netherlands)
09:30 - 09:50 Acute Behavioural Disturbance (ABD). Blair GRAHAM (Research Fellow) (Speaker, Plymouth, United Kingdom)
09:50 - 10:10 Role of self protection and team training. Dr Monika BRODMANN MAEDER (Senior Consultant, Head of Education and Mountain Emergency Medicine) (Speaker, Bern, Switzerland)
10:10 - 10:30 Interpersonal violence/ assaults towards healthcare professionals. Basak YILMAZ (Faculty) (Speaker, BURDUR, Turkey)
Skalkotas

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E21
09:10 - 10:40

Paediatric
Telephone triage / Toxicology update

Moderators: Borja GOMEZ (Pediatric Emergency Physician) (Barakaldo, Spain), Henriette MOLL (paediatrician) (rotterdam, The Netherlands)
Coordinator: Henriette MOLL (Coordinator, rotterdam, The Netherlands)
09:10 - 09:40 Improvement areas in the management of childhood poisoning exposures. Santiago MINTEGI (Section Head. Pediatric Emergency Department) (Speaker, Bilbao, Spain)
09:40 - 10:10 Recognizing the sick child: the role of vital signs in triage. Joany ZACHARIASSE (PhD-student) (Speaker, Rotterdam, The Netherlands)
10:10 - 10:40 How risky is it to get up in the morning? Ian MACONOCHIE (Speaker, United Kingdom)
MC-3

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F21
09:10 - 10:40

Free Papers Session 4

Moderators: Youri YORDANOV (Médecin) (Paris, France), Anastasia ZIGOURA (Greece)
09:10 - 09:20 #10110 - OP028 Comparing outcomes between ICU patients referred directly from A&E, and those referred within 48 hours of admission to hospital.
OP028 Comparing outcomes between ICU patients referred directly from A&E, and those referred within 48 hours of admission to hospital.

Objective

To compare mortality, length of stay and cause for admission in adult emergency department (ED) patients at the Royal Infirmary of Edinburgh with a delay in intensive care unit (ICU) admission of up to 48h with a group of patients admitted directly from the ED to the ICU.


Background

There had been no study of the differences in patient cohort, or patient outcome between patients being referred directly for critical care support, or those being admitted from a ward within 48 hours. We aimed to identify a cohort of patients who had not been referred in ED, but who required critical care support early on during their hospital admission, and therefore may have benefitted from an earlier referral to ICU.

 

Sample & method:

We performed a retrospective cohort study in a 900-bed university teaching hospital over a 3 month period analysing data for all ITU admissions over the time period. One hundred and twenty-four adult emergency department patients admitted to the intensive care unit either directly from the emergency department (direct group) or within 48h of ward admission (delayed group) were identified.  The main outcome measures investigated were mortality, length of hospital stay and cause for admission to ITU. Exclusions included those transferred to the hospital directly to a ward, those who were admitted from recovery or theatres, and those assessed in the Primary Assessment Area.

 

Findings: 

  1. Mortality in the delayed group was 8% lower than the direct group (34% vs 26%).
  2. Length of hospital stay was 11.5 days longer in the delayed group compared with the direct group (25 days vs 13.5 days).
  3. Of the patients in the delayed group, 59% of the cohort presented with sepsis.

Conclusions

Our study showed that patients in the delayed group had a lower mortality compared with the direct group which we hypothesize to be secondary to a less critically ill patient cohort. We noted an almost double length of hospital stay in the delayed group, which holds significant implications for increased morbidity in that cohort. Of these delayed patients requiring ITU care, we noted that over half presented with sepsis. These results raised the question of whether our sepsis identifiers in the ED are being utilised appropriately and/or are clinically effective. There are two sepsis tools used: Systemic Inflammatory Response Syndrome  (SIRS) criteria “ and “Quick Sepsis Organ Failure Assessment” (qSOFA).

We performed further work to assess whether the sepsis tools of SIRS criteria and qSOFA would have helped identify the delayed patients with sepsis earlier. It identified that 60% of patients scored positive based on the SIRS criteria, but only 10% of patients scored positive based on the qSOFA criteria. It highlights that while there is a strong evidence base for qSOFA in risk stratification, it may be a poor indicator of the presence of sepsis in these patients and therefore should not be the sole sepsis screening tool within the department. 


Laura ELLIOTT (Holyhead, United Kingdom), Kate EASTERFORD
09:20 - 09:30 #11316 - OP029 OXYGEN THERAPYIN EMERGENCY DEPARTMENT: IS IT OVERUSED?
OP029 OXYGEN THERAPYIN EMERGENCY DEPARTMENT: IS IT OVERUSED?

Background: Though oxygen is one of the oldest drugs available, it is still the most inappropriately administered drug. It is a very commonly used therapeutic agent and is the treatment for hypoxaemia. There has been increasing criticism of the unrestricted use of O2 therapy over the past few years, and it is still controversial. This has led to over utilization of this very expensive resource.

Methodology:This was a cross sectional observational study done in the Emergency Department (ED) of a large tertiary care hospitals in South India. All patients who were administered oxygen over a 3 week period in April 2016 were included in the study. Details of oxygen administration and outcome were analyzed. Oxygen administered without hypoxia was considered as inappropriate.A basic cost analysis was also done. This study was approved by the ethics committee of Christian Medical College, Vellore and patient confidentiality was maintained using unique identifiers.

 

Results: 15.4 % (363/2356) of the patients presenting to the ED were administered oxygen. The mean age was 50.2 ± 17 years. There was a male predominance (66.4%). Majority (67.2%) were triaged as priority 1 patients. The common reasons for initiation of oxygen therapy were dyspnea (56.7%), low sensorium (14.0%), intubated elsewhere (11.0%), polytrauma (7.2%) and seizures (4.4%).The mean duration of Oxygen therapy was 7.3 ± 4.6 hours. 36.6% of patients were administered oxygen inappropriately. This resulted in wastage of 1376 euros in three weeks through treatment cost. 65.3% were admitted, 20.1% were discharged stable from ED and 11.8% left against medical advice. ED mortality rate was 2.8% and an additional 11.6% expired during hospitalization.

Conclusion:Oxygen is inappropriately administered in 1/3 of patients presenting to ED and increases the treatment cost for patients. Oxygen therapy should be strictly regulated to minimize its wastage.


Paul KUNDAVARAM (Vellore, India), Acharya HARSHDEEP, Kumar SATISH, Selva BAGYALAKSHMI
09:30 - 09:40 #11763 - OP030 Sepsis-induced myocardial dysfunction: is it reversible?
OP030 Sepsis-induced myocardial dysfunction: is it reversible?

Background: Sepsis-induced myocardial dysfunction (SIMD) is established in about 50% of septic patients; aim of this study was to assess if SIMD is a reversible condition by mean of strain echocardiography.

Methods: Unselected patients affected by severe sepsis and septic shock admitted consecutively to a High Dependency Unit from the Emergency Department between October 2012 and December 2016 were prospectively enrolled. An echocardiogram was performed within 24 hours from the diagnosis of sepsis (ECHO1). LVEF was calculated using LV volumes derived by LV planimetry by manual tracing (Simpson’s rule) and was considered normal if >55%. The global longitudinal strain (GLS) was evaluated from apical LV views, with a commercially available system (Philips Q-LAB ver. 8.1) and was considered normal if <-14%; RV systolic function was evaluated through Tricuspidal Annular Systolic Posterior Excursion (TAPSE). In a consecutive group of survivors we repeated an echocardiogram 3 months after hospital discharge (ECHO2).

Results: Among 177 patients who underwent an echocardiogram within 24 h from sepsis diagnosis, 127 (72%) survived at 28 days and 44 patients (35% of survivors) accepted to repeat an echocardiographic evaluation after three months and they represent our study population; no significant differences were found between participants and non participants in term of LV (LVEF: 54 ±14% vs 50 ±15%; GLS -12.9 ±3.7 vs -11.8 ±3.4, tutti p=NS) and RV systolic function (TAPSE: 2.1 ±0.5 vs 1.9 ±0.5, p=NS). ECHO1 showed an LV systolic dysfunction in 26 (59%) and RV systolic dysfunction in 9 (21%); at ECHO2 LV systolic function returned to normal values in 13 patients and RV systolic function in 7, but a new systolic dysfunction was appreciated in 2 patients for LV and in 7 for RV. Considering LVEF analysis, the prevalence of LV dysfunction at ECHO1 was 49% and dropped to 23% at ECHO2; according to GLS it fell from 59% to 29% p=0.010 between ECHO1 and ECHO2, p <0.001 between evaluation by mean of GLS or by LVEF). Overall 50% of patients presented at ECHO2 a mono- or biventricular systolic dysfunction: patients with persistent dysfunction did not have a higher prevalence of coronary heart disease (14 vs 9%) or, during the acute phase, they did not develop more frequently a septic shock (29 vs 20%) or needed high-dosage vasopressors (11 vs 9%, all p=NS). Biomarkers levels in the acute phase were comparable between patients with reversible or irreversible dysfunction (Troponine: 0.43 ±1.57 vs 0.83 ±1.61 microgr/L; NTproBNP 6615 ±6501 vs 7501 ±12785 pg/mL).

Conclusions

SIMD has a significant incidence and it persists beyond the acute phase of the septic process in a relevant proportion of patients, but we did not find any useful parameter to predict SIMD reversibility; strain echocardiography was superior to conventional methods in identifying systolic dysfunction. 


Valerio Teodoro STEFANONE, Eugenio FERRARO (Firenze, Italy), Chiara DONNINI, Vittorio PALMIERI, Francesca INNOCENTI, Riccardo PINI
09:40 - 09:50 #11765 - OP031 Sepsis-induced myocardial dysfunction: which role for cardiac biomarkers in diagnostic and prognostic assessment?
OP031 Sepsis-induced myocardial dysfunction: which role for cardiac biomarkers in diagnostic and prognostic assessment?

Background: Left (LV) or right (RV) systolic ventricular dysfunction has been found in about 50% of septic patients. The aims of this study were:  1) to evaluate biomarkers’ diagnostic accuracy in identifying patients who develop SIMD; 2) to evaluate prognostic significance of biomarkers.

Methods: In 177 patients diagnosed with severe sepsis/septic shock and admitted in our ED-High Dependency Unit between August 2012 and December 2016; an echocardiogram was performed within 24 hours from admission. We evaluated LV systolic function using Global Longitudinal Strain (GLS) and Ejection Fraction (EF) measurement and RV systolic function with Tricuspidal Annular Plane Systolic Excursion (TAPSE). We divided our population in two subgroups:  patients who had a mono- or biventricular systolic dysfunction (D+) and those who hadn’t (D-). We referred to a GLS > -14% for LV systolic dysfunction and TAPSE <16 mm for RV systolic dysfunction. Biomarkers’ levels were measured both at the time of admission (T0) and after 24 hours (T1), considering them both as continue and dichotomized values (TnI: ≤0.1 or > 0.1 µg/L; NTproBNP: > or ≤ 6000 pg/mL). Day-7 and day-28 mortality were our primary end-point.

Results: Most frequent comorbidities were diabetes (27%), hypertension (55%) and neoplastic disease (31%); lung was the most common primary infection site (54%). One hundred twenty-seven patients (72%) showed an LV dysfunction and 54 (30%) a RV dysfunction; overall D+ group included 136 patients.

TnI T0 and TnI T1 levels were significantly higher in D+ patients compared with D- subjects (T0: 0.78 ±2.43 vs 0.15 ±0.29; T1: 1.00 ±2.60 vs. 0.19 ±0.48). T0 NTproBNP value was significantly higher in D+ than in D- patients (18292 ±34019 vs 9329 ±15616); dichotomized values did not show a significant different distribution between D+ and D- patients. ROC analysis showed an area under the curve (AUC)= 0.64 for T0

TnI,0.67 for T1 TnI, 0.60 for T0 NTproBNP and 0.65 for T1 NTproBNP.

Day-28 mortality was 28% (n=50). Biomarkers’ values did not show any significant association with an

increased mortality rate at univariate analysis; a more compromised value of GLS, TAPSE and EF was significantly associated with an increased day-7 and day-28 mortality; ; after adjustment for age and SOFA, an increased GLS was associated with an increased day-7 mortality (RR 1.18, IC 95% 1.04-1.35, p=0.010) while abnormal TAPSE and GLS were associated with increased day-28 mortality rate (respectively, RR 0.30, IC 95% 0.12-0.72, p=0.007 and RR 1.11, IC95% 1.01-1.25, p=0.041) while EF did not demonstrated any prognostic significance in a similar multivariable model.

Conclusion: SIMD has a significant incidence and is associated with an increased mortality rate; the levels of biomarkers, commonly considered as a result of myocardial damage, are higher in patients who present ventricular systolic dysfunction than in others but the prognostic discrimination ability is poor.


Valerio Teodoro STEFANONE, Eugenio FERRARO (Firenze, Italy), Chiara DONNINI, Vittorio PALMIERI, Francesca INNOCENTI, Riccardo PINI
09:50 - 10:00 #11768 - OP032 Echocardiographic assessment of fluid-responsiveness: a preliminary experience in a High-Dependency Unit.
OP032 Echocardiographic assessment of fluid-responsiveness: a preliminary experience in a High-Dependency Unit.

Background: Aim of this study was to examine the feasibility and diagnostic accuracy of VCCI and velocity time integral variation after passive leg raising (PLR) in an unselected population of critically ill patients admitted to a sub-intensive clinical setting.

Methods: This is a prospective, observational, pilot study. Unselected critical patients admitted in an Emergency Department High-Dependency Unit (ED-HDU) were evaluated by transthoracic echocardiography to measure vena cava collapsibility index (VCCI) and aortic velocity (AoV)  variation during PLR. Conventional LV and RV diastolic dimensions and systolic function (LV ejection fraction, EF, and Tricuspid Annulus Systolic Posterior Excursion, TAPSE) were measured. According to VCCI, patients were considered fluid-responders when the value was ≥40%. According to AoV variation after PLR, a positive hemodynamic response was defined as an increase in AoV ≥ 10%. Whenever possible, both VCCI and AoV variation during PLR were evaluated. According to echocardiographic evaluation, three therapeutic options were considered: no intervention, administration of fluids or diuretics. Any change in the therapeutic strategy by the treating physician in the following 12 hours was annotated into the clinical records.

Results: we enrolled 53 patients, mean age 73±14 years; the two most frequent reasons for ED-HDU admission were sepsis (75%) and COPD re-exacerbation (8%); in 5 (10%) patients echocardiographic evaluation was not feasible. VCCI was feasible in 35 (66%) patients, while PLR could be performed in 33 (62%). Eighteen patients were managed according to VCCI: 13 were non FR, while 5 were FR and were treated with fluid boluses. In the following 12 hours, in 4 non FR patients and in 3 FR patients therapeutic strategy was modified (7/18, 39%). Thirty-one patients were treated according to PLR: among 18 FR patients, 16 received a fluid bolus while 13 non FR did not receive fluids and this therapeutic strategy was maintained in all but one FR patient in the following  12 hours (1/31, 3%, p=0.002). In the group of patients managed by PLR 18 also underwent VCCI evaluation which was discordant with PLR in 3 patients. Finally we compared LV and RV dimensions and systolic function between patients in whom VCCI correctly identified FR (n=26) or it did not (n=10): presence of LV dilatation  (LV diastolic diameter >55mm; 10% in both groups), RV dilatation (At least 2 of the three conventional RV diameter over normal limits; 62% in patients correctly identified vs 46% in patients not correctly identified), LV systolic dysfunction (LVEF <50%; 44% vs 33%) and RV systolic dysfunction (TAPSE

 Conclusions: we confirmed a poor diagnostic accuracy for VCCI independent to LV and RV dimensions and systolic function; VTI variation during PLR showed a very good diagnostic performance.   


Caterina SAVINELLI, Federico MEO (Torino, Italy), Salvatori MATTIA, Alessandro COPPA, Francesca INNOCENTI, Riccardo PINI
10:00 - 10:10 #11772 - OP033 MEWS and lactate dosage variation: which is the best time-interval for the prognostic assessment of septic patients?
OP033 MEWS and lactate dosage variation: which is the best time-interval for the prognostic assessment of septic patients?

Introduction: The aim of this study was to compare the prognostic value of MEWS (Modified Early warning System) score and lactate dosage absolute value and trend over 2, 6 and 24 hours after admission, in order to identify the most appropriate timing to evaluate score’s evolution.

Methods: In the period November 2011-December 2016, 269 patients enrolled in a prospective study aiming to find reliable biomarkers for an early sepsis diagnosis. Patients admitted to our High-Dependency Unit from the Emergency Department with a diagnosis of severe sepsis/septic shock were eligible. At ED-admission (T0), after 2 hours (T2), 6 hours (T6) and 24 hours (T24) from the initial diagnosis, we evaluated lactate and MEWS score; score differences over 2-hour (ΔMEWS-2H), 6-hour (ΔMEWS-6H) and 24-hour time interval (ΔMEWS-24H)were calculated. Lactate absolute values (analyzed as continuous values and ≤ or >2 meq/L) and lactate clearance (dichotomized as ≤ or >10%) were evaluated at the same time intervals. The primary end-point was in-hospital mortality.

Results: Mean age of the study population was 74±14 year, 59% male gender; main comorbidities were arterial hypertension (61%), diabetes (33%), neoplasia (22%) and chronic kidney disease (24%). The most frequent infection source was respiratory (45%) and 41% of patients developed a septic shock. Overall in-hospital mortality was 26%. Mews score was significantly higher in non-survivors compared with survivors at all evaluations (T0: 4.3±2.1 vs 3.6±2.0, p=0.028; T2: 4.1±1.6 vs 2.9±1.7, p<0.001; T6: 4.3±2.1 vs 2.6±1.7, p<0.001; T24: 3.9±2.6 vs 2.3±1.7, p<0.001); repeated measures analysis confirmed a significant difference within subjects (p<0.001) and between survivors and non survivors, with a continuous decrease in the first group and a flat trend in the second one. Score variation was negligible in non survivors (T2: -0.15±1.51 vs -0.71±2.03, p=0.062; T6: -0.19±2.15 vs 0.97±2.01, p=0.023; T24: 0.11±2.61 vs -1.31±2.01, p<0.001); after dichotomization of the score variation on the basis of the median value of this study population (≤ or >-1), only at 24-hour evaluation a variation>-1 was significantly more frequent among non survivors (60 vs 34%, p=0.004). Lactate dosage was significantly higher in survivors at all evaluations except for T2 (T0: 3.8±3.9 vs 2.7±2.5, p=0.043; T2: 3.5±3.8 vs 2.4±2.6, p=0.067; T6: 3.4±3.8 vs 1.7±1,3, p=0.003; T24 4.1±5.7 vs 1.4±0.9, p=0.002); a value>2 meq/L was significantly more frequent among non-survivors only at T24 (43 vs 19%, p=0.001). A lactate clearance >10% was significantly more frequent among survivors at T6 (71 vs 48%, p=0.006) and tendentially at T24 (67 vs 50%, p=0.053), not significant at T2 (59 vs 47%, p=.208).

Conclusions: Vital signs aggregated into MEWS score and lactate dosage were significantly worst in non-survivors compared with survivors at the moment of sepsis diagnosis; a 2-hour interval appears too short to allow a prognostic evaluation. 


Chiara DONNINI, Federico MEO (Torino, Italy), Camilla TOZZI, Maria Luisa RALLI, Michela ZARI, Irene GIACOMELLI, Francesca INNOCENTI, Riccardo PINI
10:10 - 10:20 #11774 - OP034 SOFA score variation: which is the best time-interval for the prognostic assessment of septic patients?
OP034 SOFA score variation: which is the best time-interval for the prognostic assessment of septic patients?

Introduction: The aim of this study was to compare the prognostic value of score trend at 6 and at 24 hours after admission, in order to identify the most appropriate timing to evaluate score’s evolution.

Methods :In the period November 2011-December 2016, 269 patients enrolled in a prospective study aiming to find reliable biomarkers for an early sepsis diagnosis. Patients admitted to our High-Dependency Unit from the Emergency Department with a diagnosis of severe sepsis/septic shock were eligible. Exclusion criteria included presence of severe cognitive impairment inducing associated with immobilization syndrome lasting from more than three months; age

Results: Mean age of the study population was 74±14 year, 59% male gender; main comorbidities were arterial hypertension (61%), diabetes (33%), neoplasia (22%) and chronic kidney disease (24%). The most frequent infection source was respiratory (45%) and 41% of patients developed a septic shock. Overall in-hospital mortality was 26%. SOFA score was significantly higher non-survivors compared with survivors at all the evaluations (T0: 6.1±2.7 vs 5.0±2.7, p=0.013; T6: 7.8±3.1 vs 6.1±2.9, p<0.001; T24: 8.5±3.5 vs 5.3±2.6, p<0.001). Discriminative analysis by ROC curves showed an improving prognostic stratification ability in following evaluations (T0: area under curve, AUC, 0.62, 95%CI 0.54-0.70, p=0.007; T6 AUC 0.67, 95%CI 0.59-0.775, p<0.001; T24 AUC 0.77, 95%CI 0.70-0.85, p<0.001). Based on ROC curve analysis, we identified the value 3.5 as that having a good sensitivity a specificity (98 and 74%): a SOFA score lower than 3.5 was significantly more frequent among survivors at all evaluation points (T0: 32 vs 17%, p=0.039; T6: 21 vs 6%, p=0.022; T24 26 vs 2%, p=0.001). ΔSOFA-T6 (1.8± 2.3 vs 1.1± 2.0, p=0.025) and ΔSOFA-24H (2.5±3.3 vs 0.3±1.9, p<0.001) were significantly higher in non-survivors compared with survivors. A ΔSOFA value at either evaluation point >1 (median value in our study population) was significantly more frequent among non-survivors (T6: 57 vs 35%, p=0.006; T24: 61 vs 28%, p<0.001). Patients with a SOFA score >3.5 and a score variation >1 showed a significantly higher mortality rate at either T6 and T24 evaluation, compared with patients who presented only one of the previous values or neither (T6: 57% vs 38% vs 6%, p=0.003; T24: 61% vs 37% vs 2%, p<0.001).

Conclusions: Prognostic value of SOFA score was modest at the moment of sepsis diagnosis; at a 6-hour interval, useful prognostic information could be obtained both from absolute score values and score variation, which were further confirmed at the 24-hour evaluation.


Chiara DONNINI, Federico MEO (Torino, Italy), Camilla TOZZI, Maria Luisa RALLI, Michela ZARI, Irene GIACOMELLI, Francesca INNOCENTI, Riccardo PINI
10:20 - 10:30 #10116 - OP035 Spanish Pediatric residents: Variability In Education and Research In Pediatric Emergency Medicine.
OP035 Spanish Pediatric residents: Variability In Education and Research In Pediatric Emergency Medicine.

OBJECTIVE

To analyze the education in pediatric emergency medicine (PEM) given to pediatric residents and the research carried out by them in Spain.

 

METHODS

Descriptive cross-sectional study based on web surveys. First survey, regarding characteristics of PEM education and research in the Emergency Department (ED), was distributed to the directors of pediatric EDs included in the Spanish Society of Pediatric Emergencies. Respondents were asked to distribute a second survey to their residents and pediatric assistants. Only EDs with more than 30% of respondents were included for the descriptive analysis of all the variables.

Main outcome variables were the level of satisfaction within resident education (on a scale from 0 to 10) and the number of papers published in a peer-reviewed journal in the last 5 years. Multivariate analysis was made to assess associated factors between them.

 

RESULTS

First survey was sent to 83 directors and 42 (50.6%) answered it. In 33 (78.6%) EDs more than 30% of respondents fulfilled the second survey, including finally 376 (92.8%) for analysis (196, 52.1%, fulfilled by residents).

Median value of resident’s satisfaction with PEM training in each hospital ranked from 5 to 9. Factors associated with higher values were having education quality indicators, closer supervision of clinical practice and a structured evaluation of resident’s PEM skills when finishing the working shift or the rotation in the ED period.

In the previous 5 years, the average of research training activities by ED was 1 (IQR 0-3), with 11 EDs (33.3%) having no activity. Around 50% of respondents considered that research was not adequately supported at their EDs.

Level of resident’s satisfaction with research in PEM in each hospital are shown in figure 1. Sixty-eight respondents (18.1%) had published at least one paper on a peer-reviewed journal (residents, 17, 25%). Associated factors with having a paper published were the existence of a research director in the ED, having research quality indicators, self-perception of residents that the research was supported in the ED and having performed any research training activity in the previous 5 years.

Those residents with at least one paper published rated higher their education [mean= 8 (CI95% 7.34-8.66) vs those with no publications, 7.1 (CI95% 6.87-7.33)]

 

 

CONCLUSION

Significant variability in PEM education and the research was noted among Spanish pediatric residents. An adequate organization of the EDs seems to be essential to improve education and research. 


Dr Roberto VELASCO (Laguna de Duero, Spain), Santiago MINTEGI, Group For Study Of Education And Research Of Riseu .
10:30 - 10:40 #11675 - OP036 Comparison of two protocols of intravenous insulintherapy in the management of diabetic ketoacidosis.
OP036 Comparison of two protocols of intravenous insulintherapy in the management of diabetic ketoacidosis.

Background:

Diabetic ketoacidosis (DKA) is an acute and potential life-threatening complication of diabetes mellitus. The mainstay in the treatment of DKA involves the administration of regular insulin. However, the route and the dose of insulin remains controversial. This study was designed to compare the safety and the efficiency of two protocols of intravenous insulin (IV): Protocol (A) Intravenous bolus of regular insulin 0,1UI/Kg followed by a continuous IV infusion at the dose of 0,1UI/Kg/H; Protocol (B) a continuous IV infusion of regular insulin at the dose of 0,14UI/Kg/H without bolus.

 

Methods:

Prospective randomized study of patients aged more than 18 years with moderate to severe DKA hospitalized in the emergency department. Patients were devised into two groups: Group (A) received protocol (A) and Group (B) received protocol (B). Standardization of:1) the fluid therapy with normal saline and 5% dextrose 2)the potassium replacement. Data on glucose level, pH, serum bicarbonate, anion gap, intravenous fluid administration, and length of stay were collected. Outcomes data were: time to recovery, time to glucose control (<250mg/l), insulin dose to recovery, occurrence of complications: hypoglycemia, hypokalemia, recurrence of DKA.

Results:

We enrolled 164 consecutive DKA patients. Exclusion of 39 patients. The mean age = 39 +/- 18 years, sex ratio =0.97. DKA occurs more in type 1 diabetes n=87(47.6%) than in type 2 n= 64(39%) and was inaugural in 22 patients (13.4%). There were no differences between the two groups in clinical and biochemical data Group (A) versus Group (B) : mean age (37+/-17 vs. 37+/-17 years; p=0.95),sex ratio(0.84 vs. 0.88),Blood glucose level  (30.2+/-9.9 vs. 32.5+/-11.9 mmol/l; p=0.27), pH(7.14+/-0.13 vs. 7.15+/-0.12; p=0.7), anion gap (28.63+/ 5.74 vs. 28.9+/-7.21; p=0.8) ; also in outcomes data Group(A) vs. Group(B): time to recovery (17.6+/-13 vs. 17.4+/-21.5 hours; p=0.9), insulin dose to recovery (76.5+/-55.1 vs. 74.9+/-35.3 UI; p=0.8) length of stay in intensive care unit (28.3+/-18.2 vs. 32.4+/-20.3 hours; p=0.3),complications : hypoglycemia(n= 4 vs. 10; p=0.12 ) , hypokalemia (n= 32 vs. 31; p=0.33) , recurrence of DKA (n=1 vs. 7; p=0.31) .

 

Discussion:

 These two protocols of IV insulin infusion were safe and had a comparable efficiency without majoring the risk of complications.

 


Asma ALOUI, Sarra JOUINI, Rym HAMED, Hana HEDHLI, Alaa ZAMMITI, Aymen ZOUBLI, Badra BAHRI, Chokri HAMOUDA, Fatma HEBAIEB (Ariana, Tunisia)
Kokkali
10:45

"Monday 25 September"

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PH2 - S4
10:45 - 11:05

E-Poster Highlight Session 2 - Screen 4

10:45 - 10:50 #11280 - Effect of DVT and Rivaroxaban on clot microstructure and strength: An observational pilot study.
Effect of DVT and Rivaroxaban on clot microstructure and strength: An observational pilot study.

Introduction

Acute vascular disease such as deep vein thrombosis (DVT) requires oral anticoagulants to prevent progression to potentially fatal pulmonary embolism and recurrence. Approximately 1 in 1000 people are diagnosed with a DVT every year, with an annual population death from venous thromboembolism (VTE) being 0.1%. Traditionally the oral anticoagulant used is Warfarin but this is increasingly becoming superseded by direct oral anticoagulants (DOAC) as these are thought to improve the anticoagulant effect and reduce need for monitoring. Therapeutic efficacy monitoring of DOACs such as Rivaroxaban is problematic as no reliable test is currently available. A novel rheological biomarker developed at Abertawe Bro Morgannwg University Health Board/Swansea University, has focused on the measurement and quantification of clot microstructure as a biomarker of vascular disease and its treatment. Fractal dimension (df) has been shown to be a highly sensitive marker of changes in clot structure, quantifying acute vascular disease with both anticoagulation and antiplatelet therapy. This study aimed to investigate if df could quantity changes in clot microstructure in patients taking Rivaroxaban.

Methods

The prospective observational pilot study recruited patients being investigated for a DVT. Baseline blood samples were collected measuring df and standard markers. Upon diagnosis, a DVT and non-DVT group were created. The DVT group had three sample points in total, the baseline/pre-treatment sample and two additional sample points to measure the two different doses of Rivaroxaban. Sample points were at approximately 20 days with a dose of 15mg BD Rivaroxaban and finally at approximately 60 days following 20mg OD Rivaroxaban. The recruitment followed a strict inclusion and exclusion criteria with full ethical approval.

Results and Discussion

40 DVT patients (mean age 64 years [SD 14.8]; 23 male, 17 female) were recruited. Mean df on admission was 1.72 (SD 0.059). Rivaroxaban therapy reduced df to 1.69 (SD 0.051) after approximately 20 days, and subsequently increased to 1.71 (SD 0.061) at approximately 60 days. The non-DVT group of 178 patients (mean age 61 [SD 16.6]; 67 male, 111 female) had a mean df of 1.71 (SD 0.055). Despite the absence of significance in the differences in mean df at the three DVT timepoints, the trend observed suggests a measured and quantifiable reduction in clot strength associated with DOAC. Interestingly and of equal importance, analysis suggests a potentially gender based and personalised response to the DOAC. No difference between the DVT and non-DVT group suggests first time DVT may not be due to systemic clot microstructure changes. Furthermore, given the large potential difference in clot mass that changes in df represent, further studies with greater numbers are required to elucidate the effect of df during DOAC therapy in thrombotic disorders and its relationship to haemostasis and clot strength.


Vanessa Jane EVANS (Swansea, United Kingdom), Christopher Julian Charles JOHNS, Keith MORRIS, Lindsay D'SILVA, Matthew LAWRENCE, Phylip Rhodri WILLIAMS, Phillip Adrian EVANS
10:50 - 10:55 #11560 - Low-dose intravenous ketamine for treatment of acute migraine in the emergency department: a randomized placebo-controlled trial.
Low-dose intravenous ketamine for treatment of acute migraine in the emergency department: a randomized placebo-controlled trial.

Background: Migraine is a primary headache disorder that presents in the emergency department (ED). Trials show that low-dose ketamine (0.1-0.5 mg/kg) provides analgesia for acute pain in the ED, but headache patients have been excluded from these studies. We sought to investigate analgesic efficacy of ketamine for treatment of acute migraine.

Objective: To evaluate and compare analgesic efficacy and safety of low-dose ketamine to saline placebo for treatment of acute migraine in the ED.

Methods: This prospective, randomized, double-blinded, placebo-controlled trial evaluated patients aged 18 to 65 in the ED with acute migraine. Patients were randomized to receive 0.2 mg/kg ketamine or normal saline intravenously. Subjects were assessed at baseline and at 30 and 60 minutes post-treatment for Numeric Pain Rating (NRS) scores, categorical pain, functional disability, side effects, and adverse events. The primary outcome was reduction in NRS score at 30 minutes. Secondary outcomes include categorical pain and functional disability improvement, rescue medication request, patient satisfaction, and adverse events. Side effects were evaluated using the Side Effects Rating Scale for Dissociative Anesthetics (SERSDA) model. 

Results: 35 subjects were enrolled (ketamine=17, placebo=18). The average subject was 35 years old (SD=12), Caucasian (66%) and female (77%). There were no statistically significant differences in demographics except age (ketamine=39 vs placebo=31, p=0.032). There was no statistically significant difference in NRS score reduction between arms. Median NRS score reductions at 30 minutes for ketamine and placebo arms were 1 [interquartile range (IQR: 0,3.00)] and 2 (IQR: 0,3.75) (p=0.590), respectively. Categorical pain and functional disability each improved at 30 minutes in 6 (35%) ketamine subjects, while 9 (50%) placebo subjects improved in categorical pain and 7 (39%) in functional disability. Rescue medication was requested at 30 minutes with similar frequencies in ketamine and placebo arms (71% vs 78%, p=0.820). Treatment satisfaction was similar in both arms (69% vs 65%, p=0.909).  Ketamine subjects had significantly higher SERSDA scores at 30 and 60 minutes for generalized discomfort with median scores of 4 [(IQR: 2,4) vs 2 (IQR: 0,3) in placebo arm, p=0.032] and 3 [(IQR: 2,4) vs 1 [(IQR: 0,2) in placebo arm, p=0.007], respectively. Ketamine subjects had significantly higher SERSDA scores for fatigue at 60 minutes with a median score of 2 [(IQR: 1,4) vs 0.5 (IQR: 0,1.75) in placebo arm, p=0.040]. All other differences in SERDA scores were statistically insignificant. No serious adverse events occurred.

Conclusions: IV ketamine at 0.2 mg/kg did not produce a greater reduction in NRS pain score compared to placebo for treatment of acute migraine in the ED. Generalized discomfort was significantly greater in the ketamine arm at 30 and 60 minutes, as well as fatigue at 60 minutes, but no other side effects showed significant difference.


Ashley ETCHISON (Roanoke, USA), Lia MANFREDI, Moiz MOHAMMNED, Vu PHAN, Kelley B. MCALLISTER PHARMD, MBA, BCPS, Meredith RAY PHD, MPH, Corey HEITZ MD, MS
10:55 - 11:00 #11755 - A mathematical model to improve emergency department performance.
A mathematical model to improve emergency department performance.

Background: Emergency department (ED) overcrowding is a common problem in many countries and impacts on patient safety, quality of care, staff morale and cost. In England, many hospitals regularly fail to meet the national performance target of admitting or discharging 95% of patients attending ED within 4 hours. Existing evidence shows that factors external to ED (e.g. bed capacity within the hospital) can limit ED performance against this target. Our objective was to assess, for a UK hospital, the relative extent to which different external factors hinder performance against the 4-hour target and identify the scope for improving performance by reducing the time associated with key processes in the ED.

Methods: This study was conducted by a multidisciplinary embedded research team at University College London Hospitals (UCLH). Staff within the ED and related departments were interviewed and shadowed to identify key processes and flows of patients through ED and factors external to ED that were hindering performance. This informed the development of a mathematical model, based on a queuing network, that related the external factors to measures of ED performance (e.g. the 4 hour target). The model was used to determine the time evolution of the system (i.e. number of patients in each step of the ED process at any given time) and to measure performance against the 4-hour target under different scenarios of interest.

Results: The following external factors of interest were identified: patient arrival rates (number of patients arriving, and at what time during the day); delays due to unavailability of hospital beds for patient admission; delays due to unavailability of specialist clinicians from the main hospital to visit ED patients. The mathematical model was parametrised using data routinely collected in the ED and expert clinical input, and the impact on ED performance of these external factors and of reducing the time associated with key ED processes were quantified. For instance, we determined the extent to which delays accessing specialist clinicians and/or hospital beds currently limit ED performance and quantified performance gains attainable by shifting specialist/bed requests earlier in the patient journey. We studied the relationship between ED delays due to bed unavailability and the current pattern of inpatient discharges from the hospital during the day and used the model to quantify the gain in performance achievable by shifting inpatient discharges to earlier in the day.

Conclusion: The mathematical model enabled a better understanding of reasonable expectations for ED performance at UCLH given external factors that cannot be controlled by ED staff. The model results are being used to help ED staff prioritise interventions aimed at reducing the effects of overcrowding in the department. The study suggests that an improved synergy between different areas of the hospital could potentially lead to substantial gains in ED performance.


Luca GRIECO, Sonya CROWE, Martin UTLEY, Cecilia VINDROLA, Victoria WOOD, Naomi FULOP, Harriet WALTON, Samer ELKHODAIR (London, United Kingdom)
11:00 - 11:05 #11781 - The effect of neutrophil/lymphocyte ratio to the prognosis and the duration of hospitalization in adult patients diagnosed with ileus in the emergency room.
The effect of neutrophil/lymphocyte ratio to the prognosis and the duration of hospitalization in adult patients diagnosed with ileus in the emergency room.

Objective: Ileus usually presents with acute abdomen and patients with ileus frequently need operation and hospitalization. High white blood cells (WBC) levels are associated with acute abdomen. The purpose of this study is to analyze the relationship between Neutrophil/Lymphocyte ratio and the time of hospitalization and the prognosis of the disease.

Material and Methods: The patients who applied to the Emergency Medicine Department of University of Health Sciences Ümraniye Research and Education Hospital between January 1st 2013 and December 31st 2015 with abdominal pain, diagnosed with ileus and hospitalized were scanned retropectively. The leukocyte, hemoglobin, neutrophile and lymphocyte counts, the time of hospitalization, the imaging technique used for diagnosis, the presence of malignity, and mortality rate were recorded. The relationship between NLR and the duration of hospitalization and the rate of mortality were studied in the patients who were diagnosed with ileus. 

Results: 251 patients were included in this study. 143 (57%) were male. WBC levels were studied in patient's presentation to the ED. The median WBC value of the deceased patients were 13 (9.07-15.90), and it was 10.90 (8.74-13.77) in patietns who survived which was statistically insignificant (p=0.201). Mean NLR of the patients who passed was 11.65 (3.29 - 18.83), and it was 5.21 (3.30 - 8.38) for patients who survived which was statistically significant (p=0.03, Man-Whitney U Test). A multiple linear regression was calculated to predict mortality. Age and NLR were significant predictors of mortality (p=0.014 and p=0.045, respectively). (Table 1) Clinical utility of NLR is shown in (Table 2).  In our study, the NLR was significantly higher in deceased patients (p=0.03). 

Discussion: Leukocyte level usually increases in the patients with acute abdomen but it is not specific and can be effected from other inflammatory diseases (1).Neutrophile and lymphocyte values in peripheral blood sample show variability in systemic imflammatory conditions (2). In recent studies, NLR is found useful for evaluating the degree of  the imflammatory response (3). In our study, the NLR was significantly higher in deceased patients (p=0.03). Also, mortality and duration of hospital stay was correlated. These results show correlation with other studies in the literature.

Conclusions:  NLR is a cheap and widely accessible laboratory test and can be used for predicting mortality in patients with ileus. More randomised studies in larger populations are needed for getting stronger evidence.


Selma ATAY, Serkan Emre EROGLU (ISTANBUL, Turkey), Gokhan ISAT, Muzaffer Mehmet ISLAM, Gökhan AKSEL
E-Poster Area

"Monday 25 September"

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PH2 - S5
10:45 - 11:05

E-Poster Highlight Session 2 - Screen 5

10:45 - 10:50 #10486 - Comparison of intranasal ketamine versus intravenous morphine in pain relief of patient with bone fracture: A double-blind, randomized clinical tria.
Comparison of intranasal ketamine versus intravenous morphine in pain relief of patient with bone fracture: A double-blind, randomized clinical tria.

Background: Bone fractures are one of the three most important complications during accidents that fixation
and pain control are the most important management for these complications. The aim of this study was to
compare the effect of intranasal ketamine versus intravenous morphine in the treatment of pain in patients
with bone fractures.
Materials and Methods: In this double-blind clinical trial, 104 patients with bone fractures recruited from
the emergency department (ED) from 2015 to 2016 were randomly divided into two groups. Patients in the
ketamine group received 1mg/kg intranasal ketamine and patients in the morphine group received 0.1mg/kg
intravenous morphine. Then the severity of pain, hemodynamic parameters and side effects in the both
groups were measured for each 5 minutes.
Results: Results showed that the mean of pain score at different time intervals (from first 5 minutes until 20)
in the ketamine group were lower than the morphine group, of which in the 5th minute, in morphine group
was 5.19 and in ketamine group was 3.51 (P<0.001). Moreover, the analgesic effect of ketamine was started
faster, which was 2.36 min, hence in the ketamine group was 5.09 min (P=0.0034). Finally, we found that the
complications such as nausea and vomiting were significantly lower in patients receiving intranasal ketamine
(9.6% vs. 44.2%, P<0.001, and 3.8 % vs. 32.7 %, P<0.001).
Conclusion: Considering the results of our study and others’ experiences with intranasal ketamine, and its
benefits, including needle-free drug delivery, ease of use, non-opioid nature and ready access properties, this
novel medicine delivery method merits further research in patients with acute pain due to limb fracture.
Early application of low doses of ketamine following trauma-induced pain such as limb fracture may provide
acute pain relief and reduce the probability of chronic pain and merits further study.


Somayeh GHARIBI (Ahvaz, Islamic Republic of Iran), Kambiz MASOUMI, Arash FOROUZAN, Motamed HASAN
10:50 - 10:55 #11293 - Resuscitation training for parents of high-risk neonates: experience of an Italian Surgical and Medical Department of Neonatology (DNMC) in a tertiary-care children’s hospital.
Resuscitation training for parents of high-risk neonates: experience of an Italian Surgical and Medical Department of Neonatology (DNMC) in a tertiary-care children’s hospital.

Background

Cardiopulmonary arrest is rare in children, but the survival rate is poor (0-27%). Training parents is of pivotal importance, especially for babies with high risk of cardiopulmonary arrest due to prematurity, congenital heart defects or chronic pulmonary disease. Our project aims to teach parents of high-risk babies admitted to our NICU on cardiopulmonary resuscitation (CPR) and foreign body ingestion maneuvers, before their infant's discharge.

Methods

Parents of high-risk babies, defined as prematurity, severe congenital heart defects, chronic pulmonary disease (including pulmonary hypoplasia due to congenital diaphragmatic hernia), gastrointestinal anomaly (including esophageal atresia), apnea spell, and need for tracheostomy, discharged from the DNMC of the Bambino Gesù Children’s Hospital between February and November 2016 were educated to perform CPR and foreign body ingestion maneuvres by certified instructors, following ILCOR 2015 guidelines, during weekly 2-hour courses. In a group of parents of babies with tracheostomy, home ventilation, airway management and tracheostomy care were also explained.  Parents completed a questionnaire to test attitudes towards CPR before and after training. The questionnaire was proposed again, by telephone call, 3 to 6 months after the course.

Results

Over the 10 month-period, 135 caregivers (71 mothers, 48 fathers, 9 grandmothers/grandfathers, 7 uncles/aunts) of 97 high-risk neonates were educated. Babies were affected by prematurity (62%), congenital heart defects (41%), chronic pulmonary disease (32%), gastrointestinal malformations (12%), apnea (10%), tracheostomy (6%). Parents were highly motivated to learn CPR. Among them, only 15% had previously performed a CPR course.  During the practical sessions, parents demonstrated good performances, in particular to heart massage with adequate depth and rate of the compressions faced to the foreign body ingestion maneuvres. The correct questionnaire rate was 30% and 85% before and after the course, respectively. In a subset of 60 parents, the survey was proposed again, by phone, 3 to 6 months later (average 4.5 months) to test skill retention. The prevalence of  correct answers decreased from 85% to 65%.

Conclusion

Based on our results, and consistently with other reports in the literature, a program of CPR for parents of babies with high risk of cardiopulmonary arrest should be planned in Neonatology and Neonatal Intensive Care Unit when the baby is going to be discharged home. Considering the decrease of the right answers to the delayed questionnaire, further evaluation should be done to establish the best interval for CPR training repetition.


Maia DE LUCA, Massimiliano GRAZIANI, Michela MASSOUD, Annabella BRAGUGLIA, Valentina FERRO, Nicola PIROZZI, Emanuela TIOZZO, Antonino REALE, Alberto VILLANI, Paolo ROSSI, Andrea DOTTA, Pietro BAGOLAN, Maria Antonietta BARBIERI, Francesco Paolo ROSSI, Anna Maria MUSOLINO (Rome, Italy)
10:55 - 11:00 #11485 - The prognostic value of early lactate clearance to predict short-term mortality in critically ill patients.
The prognostic value of early lactate clearance to predict short-term mortality in critically ill patients.

Introduction: Hyperlactatemia has been found to be a risk factor for mortality in critically ill patients. Until now, no definitive research has been carried out into whether serial measurements or lactate clearance over time can be used as a prognostic marker in a clinically unwell population in the emergency department (ED).

Objective: To evaluate the predictive value of lactate clearance and to determine the optimal cut-off value for predicting short-term mortality in critically patients admitted in ED.Methods:  A prospective observational study was performed over 10 months. Inclusion of adult patients whose blood level of lactate was measured. Serial lactate levels in ED admission and 6 hours later were measured. Lactate clearance, percent decrease in lactate level in 6 h ((lactate admission – lactate 6 hours) x 100/lactate admission) was calculated. The main outcome measure was 7-day mortality.

Results: Inclusion of 170 patients. Mean age was 59 ± 21 years. Sex ratio = 1.53. The overall mortality at the seven day was 22%. The median admission lactate was 3 mmol/L [2,5]. Survivors compared with nonsurvivors had a lactate clearance of 30.2 ±69.9 vs. 21.8 ±40.6%, respectively (p=0.01). Based on Area Under the Curve in receiver operating characteristic analysis, lactate clearance have a significant inverse relationship with short-term mortality (0.65, 95% CI [0.47 to 0.81]), with a cut-off at 20%. Patients with a lactate clearance >20%, relative to patients with a lactate clearance <20%, had a lower short-term mortality rate (p =0.05).

Conclusion: Lactate clearance early in the hospital course may is associated with decreased mortality rate. Patients with higher lactate clearance after 6 hours (>20%) of ED intervention have improved outcome compared with those with lower lactate clearance.


Hanen GHAZALI (Ben Arous, Tunisia), Hedia GNENA, Morsi ELLOUZ, Anware YAHMADI, Wided BAHRIA, Ahlem AZOUZI, Sawsen CHIBOUB, Sami SOUISSI
11:00 - 11:05 #11559 - Procedural Sedation: checklists and electronic databases as a means of improving patient safety - 2016 Update.
Procedural Sedation: checklists and electronic databases as a means of improving patient safety - 2016 Update.

Background: Procedural Sedation rates are rising exponentially in the Emergency Department and consequently measures have to be taken to stratify risk and avoid adverse events. Provision of safe sedation is an area of practice which benefits particularly from standard operating procedures and therefore the Royal College o Emergency Medicine (RCEM) published 7 standards in 2015. 

Aims: To ascertain whether the introduction of a mandatory sedation checklist and electronic database (Bamboo) following the 2015 audit has improved our documentation rates so far as to demonstrate high levels of compliance with the seven RCEM standards.

Methods: In 2015, data was collected from the procedural sedation logbook resulting in 50 consecutive patients between 27/07/2015 and 12/11/2015. 46 patients were included in the audit due to full data set availability. In 2016, data was extracted from all entries on the new trust electronic database resulting in 50 consecutive patients between 01/09/2016 and 13/11/2016. 

Results: ASA grade, anticipation of difficult airway and fasting status rose from 8.7%, 10.6% and 32.6% to 84%, 96% and 98% respectively. Consent was recorded in 98% of cases up from 21/7% the previous year. All team members were recorded as present 76% of the time, an increase from 56.5%: The most common missing member of the team on record was nurses. Patients were monitored with the required ECG/Capnography?NIBP and pulse oximetry in 98% of cases up from 39%. No specific information was recorded to demonstrate use of oxygen to the point of discharge. Fulfillment of discharge criteria was only documented in 39% of cases, down from 41% in 2015. 

Conclusions: Our documentation rate has significantly improved over the last year and consequently we are not far from adhering to the RCEM standards 100% of the time. 

Recommendations: All procedural sedation must be recorded on the electronic database with specific improvements to ensure extra details are documented: Patient consent, monitoring (specifically that it includes ECG/Capnography/NIBP and pulse oximetry and that nursing staff are present. As a matter of safety, we must add in the discharge criteria for all patients being considered for discharge and that we ensure that we meet these. 


Leah SUGARMAN, James GREEN (Brighton, United Kingdom)
E-Poster Area

"Monday 25 September"

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PH2 - S1
10:45 - 11:05

E-Poster Highlight Session 2 - Screen 1

Moderators: Yonathan FREUND (PUPH) (Paris, France), Agnès RICARD-HIBON (Medical Chief) (Pontoise, France)
10:45 - 10:50 #9925 - Preadmission Use of Calcium Channel Blocker Improves the Outcome of Sepsis - A Population-based Propensity Score Matched Cohort Study.
Preadmission Use of Calcium Channel Blocker Improves the Outcome of Sepsis - A Population-based Propensity Score Matched Cohort Study.

Abstract

IMPORTANCE Use of calcium channel blockers (CCBs) has been found to improve sepsis outcomes in animal studies and one small clinical study. Whether the pre-admission use of CCBs would confer beneficial effects to patients with sepsis requires validation by a large population-based study.

 

OBJECTIVE To determine whether the use of CCBs is associated with a reduced risk of mortality in patients with sepsis.

 

DESIGN, SETTING, AND PARTICIPANTS We conducted a population-based cohort study using the National Health Insurance Research Database of Taiwan. From 1999 to 2011, hospitalized sepsis patients were identified by ICD-9 codes compatible with the sepsis-3 definition.   

 

EXPOSURES Use of CCBs or beta blockers. Beta-blocker was used as an active comparator, to examine the influence of healthy user bias. Propensity score (PS) adjustment and matching were used to adjust for unbalanced covariates between users of specific medication of and nonusers.

 

MAIN OUTCOMES MEASURES The primary outcome for the analysis is 30-day all-cause mortality. The secondary outcomes are 90-day all-cause mortality, septic shock, and acute respiratory failure.

 

RESULTS Our study identified 51,078 patients with sepsis, of which 19,742 received CCB treatments prior to the admission. Use of CCB was associated with a reduced 30-day mortality after PS adjustment (HR 0.94, 95% confidence interval, 0.89-0.99), and the beneficial effect could extend to 90-day mortality (HR, 0.95, 95%CI, 0.89, 1.00). In contrast, use of beta-blocker was not associated with an improved 30-day (HR, 1.06, 95%CI, 0.97, 1.15) or 90-day mortality (HR, 1.00, 95%CI, 0.90, 1.11). On subgroup analysis, CCBs tend to be more beneficial to patients with male gender, aged between 40 and 79, with a low comorbidity burden, and to patients with cardiovascular disease, diabetes, or renal diseases.

 

CONCLUSIONS AND RELEVANCE In this national cohort study, preadmission CCB therapy before sepsis development was associated with a 6% reduction in mortality when compared to patients who have never received a CCB. 


Chia-Hung YO (Taipei, Taiwan), Kuang-Chau TASI, Chien-Chang LEE
10:50 - 10:55 #11332 - Comparison between problem based and case based learning versus Lecture based learning in training of ER medicine in first year residents of family medicine in Hospital General Universitario Gregorio Marañón (HGUGM).
Comparison between problem based and case based learning versus Lecture based learning in training of ER medicine in first year residents of family medicine in Hospital General Universitario Gregorio Marañón (HGUGM).

Background: In recent years lecture based learning (LBL) compared to Problem and case based learning (PBL-CBL) have been proven to be methods that improve training of residents. There are still not enough studies that analyze the importance of these methods in the medical Emergency area.

This study had as purpose to analyze the improvement in training given by the grades obtained in the Medical ER rotation of first year residents of family medicine comparing 2 course methods LBL group vs. PBL-CBL group.

Methods: Study type: Historical Cohorts. Universe of study: we analyzed the grades of the total of first year residents of family medicine that started their Medical ER rotation In HGUGM in the years 2012, 2013, 2014, 2015, 2016. We analyzed specifically the grades in the variable acquisition of theoretical knowledge, doctor-patient relationship, and rational use of resources. Statistical analysis was done with Excel, and SPSS (Pearson’s Chi-squared).

Results: In the years 2012, 2013, 2014 70 first year residents of family medicine received the LBL course, in the years 2015, 2016 50 first year residents received the PBL-CBL course.

In the grade variable of theoretical knowledge acquisition 88% of the residents in the PBL-CBL course obtained a grade of 2 (1-3 grading scale, being 3 the highest grade) compared to 60% in the LBL group. Being this difference statistically relevant (p < 0,01). In the Variable doctor-patient relationship 44% of the PBL-CBL course obtained a grade of 3 compared to 4.3% in the LBL group. Being this difference statistically relevant (p < 0,003). In the variable rational use of resources 68% of the residents in the PBL-CBL course obtained a grade of 2 compared to 39.1 % in the LBL group. Being this difference statistically relevant (p < 0,03)

Discussion: There was statistically relevant difference between the PBL-CBL group compared to the LBL group in the grades of the variables of theoretical knowledge acquisition, Doctor-patient relationship and rational use of resources. In this study we observed that the methodology of the PBL-CBL course had a favorable impact in the grades on the medical ER rotation, in the variable mentioned previously compared to the LBL course. The PBL-CBL group had an improvement probably due to the practical application of the theoretical knowledge, the simulation of real situations and how to overcome problems in doctor patient relationship, and due to the application of that knowledge to rationally use the resources they have for the purpose of solving problem and cases related to real patients. 


Pavel Alexei CHISHOLM (Madrid, Spain), Alejandro YAÑEZ ANCHUSTEGUI, Erik Rodolfo CORPEÑO MONGE, Domingo SÁNCHEZ SENDÍN, Luis GARCÍA OLMOS, Andueza Lillo JUAN
10:55 - 11:00 #11655 - Implementing best practice to critical patients from disaster events through simulation-based learning program.
Implementing best practice to critical patients from disaster events through simulation-based learning program.

Objective: To develop a standardized high fidelity medical simulation (HFMS) training curriculum focusing on specific assessment and treatment of disaster-related severe injuries presenting to the emergency department.

Background: Evidence suggests that most prehospital and hospital providers are inadequately prepared to manage a multiple-casualty incident. For hospital healthcare providers, it is critical for them to develop competency in managing patients injured from disaster events. Unfortunately, some of these patients could be really critical, and understanding the pathophysiology of the injury progress is important for good quality care for the patients. Although existing disaster training systems emphasize non-technical skills, there has not yet been an in-depth analysis in identifying the competency of clinical skills for disaster personnel. HFMS is being used in rare but critical clinical events to enhance the competencies of healthcare providers.

Methods: The curriculum was developed using Kern’s 6-step approach. Problem identification, targeted needs assessment, goals, objectives, and educational strategies were developed according to evidence references and focused survey results. Five components of construct validation were used to validate the program: Content, Response process, Internal structure, Relationship to other variables, and Consequences. Contents were developed after reviewing all the related evidence references. And educational environment, setting, methods, instructor, and assessor were standardized. All checklists for assessment were validated using content validity index. And consequences were validated using pre- and post-intervention differences. The educational intervention consisted of a half-day workshop (lecture-HFMS-debriefing) for selected 24 emergency residents (6 teams). The objective of the scenario was to develop performance competency in managing critically injured patients in a disaster events, specifically, blast, radiation, and crush injuries. A checklist was developed to assess the performances of the participants. All pre-to-post differences within subjects were analyzed with paired t tests. The statistical level of significance was set at 0.05.

Results: The content validity index of performance checklist was 0.90. Pre- and post-intervention differences (percentage) for the 6 team performances were 67.7 to 84.6, 58.1 to 80.8, 51.6 to 84.6, 61.3 to 80.8, 51.6 to 65.4, 61.3 to 76.9, respectively. All results were statistically significant.

Conclusion: HFMS training program focusing on critically injured disaster victims positively affected performances of the participants.


Hyun Soo CHUNG (Seoul, Republic of Korea), Jiyoung NOH
11:00 - 11:05 #11660 - Implementing best practice to shock patients through simulation-based learning program – a pilot study.
Implementing best practice to shock patients through simulation-based learning program – a pilot study.

Background: Evidence suggests that most hospital providers are inadequately prepared to manage a critically ill patient, especially patients in shock conditions. As the care of patients become more specialized, training the residents for general care of patients is becoming more difficult. The working hour limits of residents has restricted them to be exposed to critically ill patients. The objective of this project is to develop a standardized high fidelity medical simulation training curriculum, focusing on specific assessment and treatment of shock patients. Participation of healthcare providers in this program using self-assessment tools would positively affect knowledge, skills, and attitudes toward managing patient in shock conditions.

Methods: The educational intervention consisted of a full-day course for all new residents entering following departments: Internal medicine, General surgery, Pediatric, Obstetric, Chest surgery, Emergency medicine, and Anesthesiology. The day was composed of a summary lecture, followed by session comprised of learning psychomotor skills necessary for saving shock patients, which included airway management, and ultrasound-guided central line insertion. Simulation session consisted of 5 scenarios: Anaphylactic, Septic, Cardiogenic, Hemorrhagic, and Obstructive shock. To identify the differences in knowledge and self-confidence before and after course, all participants responded to the survey with a Likert scale. Paired t-test was used to compare the knowledge and self-confidence level on pre- and post-course. A descriptive analysis was performed to determine the general characteristics of subjects and the level of awareness of the importance of clinical competency in shock management.

Results: A total of 68 residents participated in the session (25 internal medicine, 9 general surgery, 12 pediatrics, 6 obstetrics, 1 chest surgery, 6 emergency medicine, 9 anesthesiology). All self-assessment questionnaires were scored out of 10 points. The mean score for overall course satisfaction was 9.3. For the face validity, the participants’ scoring for ‘realism of the setting environment’, and ‘realism of the scenario’ were 8.0, and 8.6, respectively. The score differences in pre-and post-course scores for competency in shock recognition, differential diagnosis, stabilization, intervention, skills, and crisis management were 4.5 to 7.6, 4.2 to 7.6, 4.3 to 7.5, 4.1 to 7.6, 4.5 to 7.5, and 4.4 to 7.5, respectively. The results were statistically significant.

Conclusion: The pilot course was satisfactory to the participants. The simulation session was able to improve the confidence and knowledge of the participants in managing shock patients. The scenario and simulation environment was able to assist the participants in recognizing the importance of patient in shock conditions, and also to self-assess competency in knowledge, skills, and attitudes towards shock patients.


Hyun Soo CHUNG (Seoul, Republic of Korea)
E-Poster Area

"Monday 25 September"

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PH2 - S2
10:45 - 11:05

E-Poster Highlight Session 2 - Screen 2

10:45 - 10:50 #10779 - Management of Erysipelas in the ED: we could do better !
Management of Erysipelas in the ED: we could do better !

Introduction

Acute bacterial skin infections are a usual cause of sepsis in the Emergency Department (ED). Mostly, the diagnosis is clinical. Globally, the most common pathogens are Streptococcus pyogenes and S. aureus. Our primary concern should be the use of a adequate antimicrobials therapy under guidelines. Before the spread and diffusion of bacterial resistances, empiric antiobiotics therapy (with a large spectrum β-lactam) was favoured. The rational is now to adapt the use of antibiotics to the local ecological situation. Monotherapy should be attempted (depending on the severity), Gram-negative coverage is mostly not empirically indicated, oral antibiotics are very effective and should be preferred if possible. The aim of this study was to evaluate the management of acute skin infections in an urban ED and the adherence to clinical guidelines.

Methods

We present here, a one-year (2015) retrospective and monocentric study conducted in a french teaching hospital. During the period of the study, we included all adult patients with the diagnosis af erysipelas. We collected and analyzed all clinical, biological, treatments and evolution datas during the stay in the ED. In fine, 127 patients have been included for statistical analysis.

Results

In the study population, mean age was 73.8±11.6 years old and the sex-ratio was 1.14. Penicillin G and Amoxicillin + Clavulanic Acid were the two most prescribed antibiotics (both 32%). Pristinamycin (15%), Amoxicillin (11%), Clindamycin (6%), Cloxacillin (4%) and others (2%) were the other used antimicrobials. Mean duration of therapy was 11.6±4.2 days. More than three quarter (77% (CI95%: [66-88%])) of them were hospitalized. IV administration was mostly used (78%) in the ED. Blood cultures came back positive in 14% of cases (mostly with S. pyogenes: 42% and S. areus: 14%). Antimicrobial therapy was given with a average time of 4.6±2.7 hours after ED admission. There was no difference in term of treatment duration (p=0.7), neither in term of antibiotics used (p=0.59) between out-patients and hospitalized patients. The mortality at Day28 was 2.3% (95% CI: [0.5-5%]) in this cohort.

Conclusion

Our study highlights the poor adherence to current guidelines. The management of acute skin infections in our ED remains heterogeneous. Penicillin G remains as a good choice in this indication but Amoxicillin + Clavulanic Acid should be preserved in the absence of bacteriological justification. As well as curbing the additional cost of non-guideline prescription, adherence to guidelines is essential in order to suppress growing resistances to antibiotic treatment. Pristinamycin and clindamycin could be appropriate alternative of Peni G in this area. The choice of antibiotic therapy should take in account various factors, including safety, interactions, patient profile (age), and possibility of permitting an early discharge (early switch-therapy, IV to oral at 48 hours) and thus minimizing the costs of hospitalization.


Pierrick LE BORGNE, Sébastien KIRSCH, Florent BAICRY, Luc BILGER, Sophie COURAUD, Gabriella PINTEA, Elena Laura LEMAITRE (STRASBOURG), Pascal BILBAULT
10:50 - 10:55 #11250 - Fellows on the frontline: the next generation of emergency physicians, leaders and educators.
Fellows on the frontline: the next generation of emergency physicians, leaders and educators.

Emergency medicine (EM) was ranked the highest specialty in the 2016 GMC survey1 for workload, intensity and fatigue. College surveys2 have found that as many as 1 in 4 trainees may leave the specialty. Billions a year are spent on locums in the NHS.3

The 3 big questions to ask are : How can we recruit junior doctors into EM training posts and retain them? How can we inspire medical students into an EM career? And how can we deliver a cost effective service whilst providing quality training?

There is one solution: Fellows.

From August 2016, Brighton and Sussex University Hospitals (BSUH) created EM fellow posts. Each post consisted of 66% clinical time and 33% project time. The aim was to offer a better work-life balance and allow time to pursue other EM related interests. Applicants were required to be post foundation years. Fellowships were offered in education, simulation (both with a funded postgraduate certificate), leadership, trauma, toxicology and major incidents.

What do the fellows think of the job and does it make them want to do EM? We surveyed the fellows and 11/22 responded. 81% (n=9) agreed or strongly agreed that they had a good work-life balance and enjoyed the job. 91% (n=10) agreed or strongly disagreed that they had more time to participate in projects. 100% (n=11) would recommend the job to others. 72% (n=8) would consider a career in emergency medicine. Both of the registrar fellows who are EM trainees are continuing their training.

Every medical student on placement at BSUH ED this year was attached to an educational fellow. We aimed to encourage final year medical students to pursue careers in EM by providing a supportive and inspiring learning experience. How likely were they to consider emergency medicine as a career? We asked the students this question at the beginning of their EM placement and we asked them the same question after their placement with their dedicated educational fellow. The results were very positive. Answers were recorded on a 0-10 scale. Response rate was 100% of 39 students. The mean average before the placement was 5.3 and the mean average after the placement was 7.4. This is a difference of 2.13 (confidence interval 1.60-2.66).

And to answer the final question, these additional posts have enabled us to save £375,000 on locum spend already in the first half of this year.

We have shown how fellows can be a solution to recruitment, to retaining doctors whilst being cost effective. We are keen to explain the process further and share our successes and experiences with an international audience.

 

References in attachment


James GREEN, Helen COLLYER-MERRITT (Brighton, United Kingdom), Rosanna GRIMES, Rob GALLOWAY
10:55 - 11:00 #11286 - New system indicators to monitor prehospital and hospital survival for ambulance service patients: a study using linked data.
New system indicators to monitor prehospital and hospital survival for ambulance service patients: a study using linked data.

Background

UK ambulance services do not routinely receive information about what happens to patients following pre-hospital care. This impacts the ability of ambulance services to measure patient outcomes or evaluate care quality and performance. Measuring patient outcomes for ambulance service users has been identified as important through our consensus work with service users, service providers and service commissioners. In a Delphi study and patient and public consensus workshop, one of the highest priorities was to develop new indicators for measuring patient survival following ambulance service care. We present new survival indicators to measure survival for patients with serious emergency conditions, at multiple time-points.

Methods

We linked six-months patient level call and clinical data from one UK ambulance service with Hospital Episode Statistics (HES) Emergency Department (ED), admitted patient data and national mortality data. We identified a cohort of people who were admitted or died from one of 16 serious emergency conditions (conditions where death could potentially be prevented by a good emergency system). Multi-variable models (adjusting for age, condition and hospital effects) were created to calculate two survival measures. 1) Survival to hospital admission, within 7 days of the ambulance call; 2) For patients admitted to hospital, survival to 7 days from admission.

 

Results

Indicator 1: To identify the proportion of people with a serious emergency condition who survive to admission (within 7 days of ambulance contact). 11,264 of 187412 patients in our dataset met the inclusion criteria and had a serious emergency condition. Of these, 617 (5.5%) died and 10,647 survived to admission. The majority of pre-admission deaths occurred in older people and were within 1 day of the ambulance contact (87.8%). Pre-admission deaths were more likely for people with conditions such as ruptured aortic aneurysm, asphyxiation and meningitis.

Indicator 2:  For patients admitted to hospital, survival to 7 days from admission.

10,647 patients were admitted to hospital and 94% survived. The rate of survival decreased with age. People with septic shock, cardiac arrest, ruptured aortic aneurysm and heart failure were more likely to die, whereas people with falls age >75, road traffic accidents and asthma were more likely to survive. Most deaths occurred within one day of admission (47%).

 

Discussion

These indicators are part of a set of indicators developed by the Prehospital Outcomes for Evidence Based Evaluation (PhOEBE) project, to measure ambulance service quality and performance. The indicators presented here are system indicators that monitor pre-hospital and post admission survival rates for people with a serious emergency condition and can be used to assess trends over time and differences between geographical areas.  For example, survival may improve through service developments, such as taking the right patients to the right specialist care.


Joanne COSTER (Sheffield, United Kingdom), Janette TURNER, Richard JACQUES, Annabel CRUM, A. Niroshan SIRIWARDENA
11:00 - 11:05 #11707 - Development of a new indicator to monitor the quality and safety of ambulance service non-transport decisions.
Development of a new indicator to monitor the quality and safety of ambulance service non-transport decisions.

Background

The Prehospital Outcomes for Evidence Based Evaluation (PhOEBE) project is a five year NIHR funded research programme, which aims to identify, develop and test new ambulance service quality and performance indicators. During our 3 stage consensus research study, an important topic identified by patient and professional research participants was quality and safety of non-transport decisions. For example death or hospital admission following a non-transport decision. This is also important because the number of non-transported calls is increasing and there is huge service level variation for non-transport rates for different localities. Using our study patient-level linked ambulance and subsequent health event dataset, we developed a quality and performance indicator to identify potential missed opportunities to improve care related to prehospital non-transport decision making.

Method

Data for 6 months of 2013 was provided by one UK ambulance service and linked to national datasets (ED, hospital admissions, mortality) using NHS Digital’s data-linking service.  We excluded calls transported to ED, people who were dead on scene, untraced calls and end of life care calls. Calls were categorised into those receiving a paramedic response and not transported and calls receiving telephone advice only. We identified hospital admissions or deaths within 3 days of the original call as being potential missed opportunities to improve care. We calculated crude and standardised rates of admission or death within 3 days of the call and created predictive models to adjust for age, condition, call outcome and deprivation.

Results

84% of calls receiving a paramedic response and not transported were traced (42796/50894). Of these 6.3% were admitted to hospital within 3 days and 0.3% died within 3 days. Low tracing rates for telephone advice only calls (24%, 2514/10634) resulted in the possibility of bias, therefore we conducted a sensitivity analysis to identify a range of hospital admissions (2.5% – 10.5%) and deaths (0.006 – 0.24%) within 3 days of the original call. Using predictive models we assessed the results by county, clinical commissioning group, condition, in and out-of-hours calls, using traced and non-traced calls in the denominator, and presented standardised rates using funnel plots. We also assessed the impact of excluding hospital admissions < one day.

 

Conclusions

Quality and safety of non-transport decisions is important to service users and service providers, and can be measured using linked prehospital and subsequent health event data. We developed and tested a potential prehospital non-transport quality and performance measure. This can be used to monitor deaths and admissions following prehospital non-transport decisions and to provide information about the safety of non-transport decision making. This has potential as a system level indicator for all emergency and urgent care services where patients are not-transported to hospital.

 

 


Joanne COSTER (Sheffield, United Kingdom), Richard JACQUES, A. Niroshan SIRIWARDENA, Annabel CRUM, Janette TURNER
E-Poster Area

"Monday 25 September"

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PH2 - S3
10:45 - 11:05

E-Poster Highlight Session 2 - Screen 3

10:45 - 10:50 #11333 - Syncope in the Emergency Department: an analysis of current management and risk stratification tools.
Syncope in the Emergency Department: an analysis of current management and risk stratification tools.

Introduction: Syncope in the Emergency Department (ED) presents a dilemma between accurate diagnosis, recognition of risk-factors, and cost-effective management. Approximately 50% of the UK population will experience at least one syncopal episode in their lifetime, accounting for 3% of all ED attendances and up to 6% of hospital admissions. A comprehensive, evidence based pathway to aid decision making on whether to admit or safely discharge a patient with syncope could improve patient management and resource utilisation.

Objectives: To collect data regarding the outcomes and risk characteristics of patients presenting to the emergency department with syncope to determine whether patients would benefit from the implementation of a syncope management pathway or dedicated syncope outpatient clinic.

Setting: Royal Alexandra hospital, Paisley, Scotland.

Results: 159 patients were included in the study after 12 were excluded according to set criteria. 99 (62.3%) were discharged and 60 (37.7%) admitted. The mean age was 35.7 years for those discharged and 71.4 years for those admitted. The two groups of most interest in relation to the aims were those stratified high-risk and discharged (HRD) and those stratified low risk and admitted (LRA). Of those discharged 23 (23.2%) were stratified as high risk, of those admitted 24 (40.0%) were stratified as low risk.

 When comparing these two populations LRAs were, on average, older than the HRDs (mean age 69.0 to 44.7). LRAs were more likely to attend hospital within 6 months for reasons other than syncope (29.2% to 13.0%), more likely to receive follow-up than low risk discharged patients (45.8% to 23.7%) and LRAs were more likely to receive head CT scans than HRDs (12.5% to 0%).

Conclusions: This study shows that there are patients presenting to the ED with syncope who are inappropriately admitted or discharged. Figure 1 outlines an example pathway helping to guide clinicians in decision making. Further research is required to identify exactly which patients would most benefit from referral to a specialist syncope clinic or from a management pathway to aid ED clinicians in assessing and directing care and whether its implementation is effective in real-world use.


Theo BAYSTON, Beth DOCHERTY (Glasgow, United Kingdom), Paul MCNAMARA, Monica WALLACE
10:50 - 10:55 #11463 - A comparison of the timeliness and efficiency of two triage systems, the manchester triage system and emergency severity index, in midland regional hospital tullamore and royal liverpool university hospital.
A comparison of the timeliness and efficiency of two triage systems, the manchester triage system and emergency severity index, in midland regional hospital tullamore and royal liverpool university hospital.

TITLE A comparison of the timeliness and efficiency of two triage systems, the Manchester Triage System and Emergency Severity Index, in Midland Regional Hospital Tullamore and Royal Liverpool University Hospital

INTRODUCTION An effective triage system can ensure that an emergency department (ED) runs smoothly during periods of time where patient numbers are high and resources are sub optimal. The Emergency Severity Index (ESI) assessment is shorter than that of Manchester Triage System. The MTS is in use in the Midland Regional Hospital Tullamore (MRHT) and the ESI in the Royal Liverpool University Hospital (RLUH).

The aim of this study was to determine

1 the extent of the triage assessment used in each hospital.

2 the time elapsed between;

  • patient arrival in the emergency department and time to triage.
  • triage and patient information being available to the ED staff.
  • patient information being available and first consultation with a Doctor.

3 if the availability of an advanced triage system improves waiting times

METHODS

A prospective observational study was undertaken in both EDs in Summer 2016. The time a patient entered triage was recorded and the process they underwent observed. The tasks undertaken by the triage nurse was noted. The time for notes to enter the boxes for doctor/ANP review was noted. The observed time and the duration of the  triage process as recorded on the IT system was compared if feasible. The advanced triage process (ie Bloods, ECGs etc) in each ED (formal in RLUH, adhoc in MRHT) was also observed and impact noted.

RESULTS

Data was collected on 217 and 204 patients in MRHT and RLUH respectively. The mean time for triage was 7mins 8secs and 9mins 36secs for MRHT and RLUH respectively. In both EDs, 1 in 5 patients needed no additional tasks at triage (19.8% and 20.6% respectively). A mean of 1.4 and 1.3 additional tasks were performed respectively at triage. 12.8% patients were discharged direct from triage to alternative services in RLUH. Availability of ED cards to medical staff was longer in RLUH than MRHT but time to medical review was longer in MRHT (113.9mins in MRHT vs 88.6mins in RLUH for Cat 3 patients)

CONCLUSION

In theory, the ESI should result in a shorter triage process than the MTS. In practice, this was not observed. Both systems require additional tasks to be performed at triage in the majority of patients, commonly recording vital signs and provision of analgesia. The formal advanced triage process in place in the RLUH resulted in longer delays to availability for doctor/ANP review. Due to the lack of IT systems recording the ED transfer of care to other specialties in RLUH, it is not possible to evaluate if the advanced triage process had benefits further along the patient journey.  Time until review by doctor/ANP for category 3 and 4 patients was longer in MRHT despite the longer advanced triage process in the RLUH, reflecting other factors that impact on efficient ED function eg lack of doctors or lack of cubicles.


Sophie BOYD, Emily HILL, Robert EAGER (Tullamore, Ireland)
11:00 - 11:05 #11746 - SAMe-TT2R2 score validation in Emergency Room.
SAMe-TT2R2 score validation in Emergency Room.

Background:

The SAMe-TT2R2 score has been proposed to identify patients with non valvular atrial fibrillation (AF) who maintain a high average time in therapeutic range (TTR) on vitamin K antagonists treatment (VKA). This score has been validated in several studies; either monocentric or including very selected populations in a specialized setting. Our aim was to validate this score in patients attending an Emergency Room (ER). To our knowledge this is the first report describing this score in an Emergency Room setting.

Patients & Methods:

From January 2014 to June 2014, we included in this study patients with AF on VKA consecutively seen in our ER. The SAMe-TT2R2 score was calculated for each patient and so was the TTR using the Rosendaal method, following the international normalized ratio (INR) six months, after the admission in ER. Patients with SAMe-TT2R2TTR

Data Collection:

We enrolled 394 patients with AF seen in the ER for any reason. In 271 (68.7%) cases were on AVK thromboprofilaxis.

Results & Discussion:

A number of 271 (68.7%) cases were on AVK thromboprofilaxis. The mean SAMe-TT2R2 score was 1,6(0.70 SD) points. In 202(74.5%) patients the score was 0 or 1 points and 69(25.4%) patients received 2 or more points. Up to 211(77.8%) patients were followed 6 months with mean 4,25(4,75 SD) INR determinations in this period. A total of 79 (37.4%) patients had a TTR ≥65%. Comparing high TTR vs low TTR groups (table I) we found no differences bettween demographic and clinical variables. Comparing SAMe-TT2R2 groups with TTR values we found: SAMeTT2R2=0 43%, TTR(interquartile range(IQR)26-51). SAMeTT2R2=1 40%, TTR(IQR30-49). SAMeTT2R2=2 33% TTR(IQR23-48). SAMeTT2R2=3 31% TTR(IQR19-45). SAMeTT2R2=4 NA.

A linear correlation was found in the prediction of good TTR control with the SAMeTT2R2 scale. (Fig 1). A statistically level of significance (p <0.05) was observed for SAMeTT2R2 to predict good control by the Rosendaal method grouping the patients into a “likely to achieve a high TTR” group (SAMeTT2R2 <2) and “unlikely to achieve a high TTR” SAMeTT2R2 ≥2.

Conclusion & perspective:

In a "real-world" cohort of patients attending the ER we have meassured the value of the SAME-TT2R2 score for the identification of patients who would have poor-quality anticoagulation. Higher values have been significatively associated with worse TTR control.  Thus, rather than imposing a "trial of vitamin K antagonists" for such patients (and exposing such patients to thromboembolic risks), we can a priori identify those patients who can (not cannot) do well on a vitamin K antagonists. Such patients would benefit from additional strategies for improving anticoagulation control with vitamin K antagonists or alternative oral anticoagulant drugs.



Dr Carlos DEL POZO VEGAS (Valladolid, Spain), Emilio GARCÍA MORÁN, Jaldun CHEHAYEB MORÁN, José Vicente ESTEBAN VELASCO, Enrique SERRANO LACOUTURE, Marta CELORRIO SAN MIGUEL, Saturnino HERNÁNDEZ BEZOS, Armen HAMBARDZUMYAN, Susana DE FRANCISCO ANDRÉS, Sonia DEL AMO DIEGO
E-Poster Area
11:10

"Monday 25 September"

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A22
11:10 - 12:40

Resuscitation (Cutting Edge)

Moderators: Clifton CALLAWAY (Pittsburgh, PA, USA), Othon FRAIDAKIS (Greece)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
11:10 - 12:40 Resuscitation from cardiac arrest. Clifton CALLAWAY (Speaker, Pittsburgh, PA, USA)
11:40 - 12:10 Optimized therapy for patients after ROSC. Wilhelm BEHRINGER (Chair) (Speaker, Vienna, Austria)
12:10 - 12:40 Neurologic prognosis and withdrawal of life-sustaining therapy after cardiac arrest: if, when and how? Tobias CRONBERG (Speaker, Sweden)
Trianti Hall

"Monday 25 September"

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B22
11:10 - 12:40

Prehospital (Game Changer)

Moderators: Steffen HERDTLE (MD) (Jena, Germany), Dr Jana SEBLOVA (Emergency Physician) (PRAGUE, Czech Republic)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
11:10 - 11:40 EMS: fundamental for ED Lean Management? Eric REVUE (Chef de Service) (Speaker, Paris, France)
11:40 - 12:10 Rescuing the rescuers - necessary? Dr Jana SEBLOVA (Emergency Physician) (Speaker, PRAGUE, Czech Republic)
12:10 - 12:40 Do we really need an EMS-Physician for Stroke-Patients? Steffen HERDTLE (MD) (Speaker, Jena, Germany)
Mitropoulos

"Monday 25 September"

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C22
11:10 - 12:40

Mental Health (Cutting Edge)

Moderators: Greg HENRY (USA), Christian HOHENSTEIN (PHYSICIAN) (BAD BERKA, Germany)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
11:10 - 11:40 Difficult patient or misinformed staff? Pr Jim DUCHARME (Immediate Past President) (Speaker, Mississauga, Canada)
11:40 - 12:10 Clearing patients in the ED for psychiatric admission. Greg HENRY (Speaker, USA)
12:10 - 12:40 Physician burnout and suicide - Are you at risk? Julius KAPLAN (Immediate Past President) (Speaker, NEW ORLEANS, LA, USA)
Banqueting Hall

"Monday 25 September"

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D22
11:10 - 12:40

YEMD - POCUS

Moderators: Dr Atriham ADAN (Medical Director, Emergency Department) (Houston Texas - USA, USA), Jennifer TRUCHOT (MEDECIN) (Paris, France)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
11:10 - 11:40 The impact of ultrasound on the critical patient. Gregor PROSEN (EM Consultant) (Speaker, MARIBOR, Slovenia)
11:40 - 12:10 Ultrasound and simulation: choosing the right teaching tool. Erden Erol UNLUER (Speaker, Turkey)
12:10 - 12:40 Ultrasound in the ED in 2017: an ethical imperative? Dr Atriham ADAN (Medical Director, Emergency Department) (Speaker, Houston Texas - USA, USA)
Skalkotas

"Monday 25 September"

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E22
11:10 - 12:40

Paediatric
Children as refugees

Moderators: Said HACHIMI-IDRISSI (head clinic) (GHENT, Belgium), Santiago MINTEGI (Section Head. Pediatric Emergency Department) (Bilbao, Spain)
Coordinator: Santiago MINTEGI (Coordinator, Bilbao, Spain)
11:10 - 11:40 Refugee children's health. Dr Ruud G NIJMAN (academic clinical lecturer) (Speaker, London, United Kingdom)
11:40 - 12:10 Health problems of refugee children: more than we think. Ozlem TEKSAM (PEDIATRICS) (Speaker, ANKARA, Turkey)
12:10 - 12:40 Children among the refugees – (un)usual needs in unusual conditions. Zsolt BOGNAR (Head of Department) (Speaker, Budapest, Hungary)
MC-3

"Monday 25 September"

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F22
11:10 - 12:40

Free Papers Session 5

Moderators: Felix LORANG (Consultant) (Erfurt, Germany), Anastasia ZIGOURA (Greece)
11:10 - 11:20 #9835 - OP037 Hygiene in the emergency medical service calls for attention.
OP037 Hygiene in the emergency medical service calls for attention.

Background     Contaminated environmental surfaces are known provide an important potential source for transmission of healthcare associated pathogens  and prehospital treatment have been associated to increased risk of infection. Nevertheless, few studies present and discuss prehospital hygiene, resulting in limited knowledge and understanding of related challenges. Our aim was to assess microbial contamination and influencing factors in order to assess the extent of the risks and illuminate eventual solutions.

Methods          A nationwide, semi-blinded, cross-sectional study was conducted in Denmark from August to November 2016. Using a combined swab/agar method, samples from environment, equipment and personnel were randomly collected from 80 ambulances and crew, in-between patient courses, after cleaning. Focus was on colony forming units (cfu) and healthcare associated pathogens. In addition, explanatory variables e.g. hours from last thorough cleaning, area of service (rural/city) and number of patient courses within the shift, were collected and used in bivariate analyses.

Results              800 sites, showed an average of 11.3 cfu/cm2 (environmental sites e.g. blood pressure cuff, patient harness and defibrillator 5.01 cfu/cm2, hands of the personnel 11.1 cfu/cm2 and uniforms 30.6 cfu/cm2). Staphylococcus aureus, Enterococcus and Enterobacteriaceae were found on 10, 3.4 and 0.5 % of the imprints, respectively. One imprint was MRSA, two were VRE but none was ESBL. Furthermore, we found no correlation between the explanatory variables and the degree of microbial burden.

Conclusion      Our study underlines that microbial contamination and related challenges in the EMS calls for further attention. As seen in prior studies, several sites were contaminated with healthcare associated pathogens.  However, neither time from cleaning, number of patients nor area of service were of influence on the degree of contamination, hence not contributing to an explanation. Future research on hygienic challenges and routes of transmission is recommended.


Heidi Storm VIKKE (Kolding, Denmark), Matthias GIEBNER, Hans Jørn KOLMOS
11:20 - 11:30 #11059 - OP038 Prehospital echocardiography during resuscitation impacts treatment decisions in a physician-staffed helicopter emergency medical service: a prospective observational study.
OP038 Prehospital echocardiography during resuscitation impacts treatment decisions in a physician-staffed helicopter emergency medical service: a prospective observational study.

Background

Patients in cardiac arrest must receive algorithm-based management such as basic life support and advanced (cardiac) life support. International guidelines dictate diagnosing and treating any factor that may have caused the arrest or may be complicating the resuscitation. Ultrasound is recognized to be of potential value in this process. Also, it is shown to be feasible in a prehospital setting. We aim to determine the impact of prehospital echocardiography during cardiopulmonary resuscitation (CPR) and its impact on treatment decisions in a Dutch physician-staffed helicopter emergency medical service (HEMS).

Methods

We conducted a prospective, observational study from February 2014 through October 2016 of patients treated by the Nijmegen HEMS. Inclusion criteria were CPR irrespective of its cause and concurrent echocardiography. Echocardiography-trained physicians performed the examinations within the same time window where chest compressions are interrupted to analyze heart rhythm. Data collection included patient demographics; type of incident; CPR details and outcome; vital signs; ultrasound findings (ventricular dimensions; global myocardial function; any pericardial fluid); physician-reported image quality and ease of procedure; impact on treatment decisions. Outcome parameters were: impact on treatment decisions; characteristics of the population; feasibility of echocardiography in this setting.

Results

Of 6694 recorded scrambles and 3229 patients treated, 425 underwent CPR. In 56 patients 102 ultrasound examinations were documented. Treatment decisions were impacted in 49 patients (88% - CI 79.5-96.5%) and in 62 (61% - CI 51.5-70.5%) ultrasound examinations. Overall, we found 78 changes. They were termination of CPR in 32 patients (57%) and continuation hereof in 21 (38%). Other changes were related to fluid management (14.3%), adjustment of drugs and doses (14.3%), and choice of receiving hospital (5.4%). The causes of cardiac arrest were trauma (48%), cardiac (21%), medical (14%), asphyxia (9%), and other (7%). The ease of the entire procedure was scored a median of 7 (numeric rating scale 1-10) and image quality per examination good (59%), moderate (29%), or poor (12%).

Discussion

Ultrasound impacts management in 88% of patients. This is in accordance to results of (peri-) resuscitation studies by Breitkreutz (78%) and Shokoohi (12%-31% in different categories, overall unknown). Ultrasound images can help explain futile care to caregivers and relatives, even if the sensible decision already is to terminate CPR. Prehospital (traumatic) CPR is often impeded by stress, time pressure, environmental factors including a restricted workspace, and an inaccessible ultrasound machine. This likely explains the limited number of inclusions. In conclusion, prehospital ultrasound during CPR in our HEMS significantly impacts patient treatment. This suggests echocardiography should be a standard tool in every prehospital resuscitation.


Rein KETELAARS (Nijmegen, The Netherlands), Christian BEEKERS, Geert-Jan VAN GEFFEN, Nico HOOGERWERF
11:30 - 11:40 #11071 - OP039 Can additional ems call triage time improve resource utilisation?
OP039 Can additional ems call triage time improve resource utilisation?

Background

Time based standards have been used as a key performance measure for EMS internationally, despite a lack of evidence that they actually lead to good clinical care. Achievement of standards in an environment of rising demand potentially leads to operational behaviours that may be inefficient such as dispatching multiple vehicles before the problem is known.  In England, the Ambulance Response Programme is developing new operational models of care. One strategy has been to test if additional call triage time before starting the response interval clock start can lead to better use of resources and improved dispatching.

Methods

A controlled before and after time series analysis of a new intervention – Dispatch on Disposition (DoD)– comprising a short set of pre-triage questions to identify time critical emergencies needing immediate dispatch of a resource and up to 4 minutes to triage all other calls (compared to the existing 60 seconds). DoD was implemented in 6 of the 10 regional services in England and 4 services were control sites. We measured weekly trends in average resource allocation per call and resources on scene for different call types (life-threatening, emergency, urgent) for 1 year before and 7 months after implementation, and used time series regression models to compare changes between intervention and control sites adjusted for seasonality, call volumes and hours lost at hospital handover. We also conducted a survey of dispatch and operational staff.

Results

There was a statistically significant reduction in average resources allocated per incident of -0.1 for life-threatening calls, -0.06 for emergency and -0.12 for urgent, and a reduction in resources arriving on scene per incident of -0.006 for life-threatening calls and -0.02 for urgent in the intervention groups compared to control. Scaled up the resource allocation reductions will potentially produce an additional 10243 whole resources available to respond per week in England. Dispatch staff reported they were better able to manage call queues and allocate the right rather than any response. Operational staff reported a substantial reduction in calls where they were cancelled before arriving on scene.

Conclusions

Prior to DoD ambulance services in England had to dispatch a resource within 60 seconds of receiving an emergency call and in order to achieve a response time of 8 minutes for the most serious calls multiple resources could be sent before establishing if the call was serious. Allowing additional time to properly triage calls other than those likely to be life-threatening has created efficiencies by substantially reducing multiple resource allocations and freeing up vehicles for other calls. In an environment of increasing demand and diminishing resources this allows better use of existing resources.


Janette TURNER (Sheffield, United Kingdom), Richard JACQUES, Annabel CRUM
11:40 - 11:50 #11172 - OP040 Improving data quality in a United Kingdom registry of Out-of-Hospital cardiac arrests through data linkage between the Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) project and the Office for National Statistics.
OP040 Improving data quality in a United Kingdom registry of Out-of-Hospital cardiac arrests through data linkage between the Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) project and the Office for National Statistics.

Background: The Out-of-Hospital Cardiac Arrest Outcomes (OHCAO) project aims to understand the epidemiology and outcomes of out-of-hospital cardiac arrests (OHCA) across the UK. Significant variation exists between ambulance services in outcomes for patients with attempted resuscitation following OHCAs. Importantly, a great deal of the variability of reported outcomes can be traced back to the quality of data that results are based on.

This study is a sub-project of OHCAO and aims to establish the feasibility of producing a registry of OHCAs by linking OHCAO data to the Office for National Statistics (ONS) mortality data, via NHS (National Health Service) Digital, to improve data quality and establish accurate 30-day survival outcomes for OHCAs.

Methods: Data were collected from 1st January 2014 to 31st December 2014 as part of a prospective, observational study of all OHCAs attended by ten English NHS Ambulance Services. 28,729 OHCA cases had resuscitation attempted by Emergency Medical Services and were included in the study. Of these, a randomly selected sample of 3,120 cases (10% of total) were securely transferred to the ONS. This allowed OHCAO demographic data to initially be matched to NHS patient demographic data, using the NHS Digital list cleaning service to return previously missing data. Following this, cases were linked to ONS mortality data to provide accurate death dates where applicable to calculate 30 day survival.

Results: A total of 80.5% of OHCAO cases were matched to the ONS database. OHCAO collected complete demographic datasets on 868 (27.8%) cases. Using the linkage process, missing demographic data was retrieved for 72.7% of the 2,249 cases with incomplete data. Confirmation of 30-day survival improved by 37.6% with a reduction in unknown 30-day survival status from 46.1% to 8.5%. The most important data point required for linkage was the NHS number which provides a unique patient identifier. However, it was only retrieved by the OHCAO project for 31.7% of cases. This study found that if at least 3 other demographic data points were collected, the NHS number could be retrieved using the linkage process in up to 89.9% of cases.

Discussion: Ensuring high data quality is essential as this forms the basis of decisions that ultimately impact on changes in care and healthcare resource allocation. Data linkage was shown to successfully improve the quality of OHCA demographic data and survival status 30 days after OHCA. Importantly, this process has allowed the provision of demographic details to allow patients to be followed longitudinally, potentially to assess morbidity following OHCAs. The linkage process can be used to produce a registry of OHCAs and information gained from this can be fed back to institutions providing source data to improve OHCA outcomes.

 


Sangeerthana RAJAGOPAL (Warwick, United Kingdom), Scott BOOTH, Claire HAWKES, Chen JI, Terry BROWN, Samantha BRACE-MCDONELL, Sarah BLACK, Imogen GUNSON, Kim KIRBY, Niroshan SIRIWARDENA, Robert SPAIGHT, Gavin PERKINS
11:50 - 12:00 #11602 - OP041 Fire Medical Response Early Indications of Clinical Value.
OP041 Fire Medical Response Early Indications of Clinical Value.

 

Fire Medical Response Early Indications of Clinical Value

Background

In the UK, response to serious medical emergencies has been solely provided by the National Health Service (NHS), but UK Fire and Rescue Services (FRS) are increasingly establishing a presence as ‘Fire Medical Responders.’  FRS are highly developed organisations with the potential to offer a rapid response to medical emergencies. They also operate with ‘latent capacity,’ compared to health care resources, creating an opportunity to assist in meeting urgent patient need.  The aim of this study was to investigate the impact of FRS co-responding on the delivery of emergency medical response.’

Methods

An observational study generating data from 42/50 Fire & Rescue Services, FRS, during 2016 to assess current involvement in EMS co-response.  We have a) compared response time distributions between Fire and Ambulance services b) described the types of calls attended by FRS crews c) estimated the likely survival benefit based on optimal response time curves for successful defibrillation in out of hospital cardiac arrest and d) conducted an economic evaluation.

Results

There was a statistically significant difference in response performance between the Fire and NHS Ambulance Services, with FRS arriving first in 62% of cases, NHS Ambulance Service arriving first in 23% and no record of who arrived first in 25%.   For every 10% increase in the proportion of ‘whole time duty fire stations’ [stations with 24 hrs/day staffing], there was an 8.4% improvement in response time and mean 84 second shorter response time compared to stations using retained staff utilised via an “on call” system. The top 5 clinical categories attended by FRS were: cardiac problems/chest pain (23%); breathing problems (13%); unconsciousness (13%); cardio-respiratory arrest (9%), and fitting (9%).  From the response time improvement data, we have estimated a potential survival benefit of 1.2 Quality Adjusted Life Years (QALYs) gained.  Using NICE figures of £20,000 per QALY, there is a potential benefit of around £23,000 per critical medical event but this figure should be treated with caution as it is a theoretical extrapolation and the study was not designed to measure individual patient outcome.

Conclusions

Fire Medical Responding is a new development in the UK, having previously operated a strict demarcation between fire and ambulance services although it is well-established in some European countries and in other parts of the world, such as the USA.  This study found FRS can frequently respond more rapidly to medical emergencies than the ambulance service and that they can be appropriately deployed to time critical conditions. This offers an opportunity to employ an underutilised, potentially life-saving resource more widely at low cost.  There is a potential life-saving advantage in further developing and evaluating a Fire Medical Response capability.

 


Julia WILLIAMS, Andy NEWTON (Bridgewater, United Kingdom)
12:00 - 12:10 #11971 - OP042 IMMIGRATION PROBLEM IN GREECE, The impact for Emergency Medical System in Attica Creece 2.
OP042 IMMIGRATION PROBLEM IN GREECE, The impact for Emergency Medical System in Attica Creece 2.

IMMIGRATION PROBLEM IN GREECE,

The impact for Emergency Medical System in Athens

 

INTRODUCTION

Over 10000 refugees have lost their lives in the Mediterranean since 2016 in their endeavor to reach the EU

In the first half of 2016 there were 2809 recorded deaths

Immigration today is one of the most important problems in the world and at the same time a purely anthropocentric challenge for all stakeholders, especially the EMS in GREECE (National Centre for Emergency care) (First responder)

SCOPE-METHOD

    In 2015 Greece became the main point of entry into the EU for refugees and immigrants from Turkey. It is estimated that 850,000 people attempted the dangerous passage of the Aegean Sea

Of these, more than 53,000 refugees remained in Greece Most of them (about 90%) come from Syria, Iraq, and Afghanistan. Among them are small children, people with severe health problems, pregnant women, and infants

Disease-related diseases (refugees) are often unexpectedly severe and complex (extreme age groups - infants, children, and the elderly)

To describe & estimate the effect on EMS/NHS

CHARACTERISTICS:

Children make up 48% of the refugees, while for adults, 30% of them are men and 22% are women

  • 10% of refugees in Greece are only 2 to 4 years old
  • 14% are aged between 5 and 9 years
  • 11% are aged 10 and 14 years old

There are camps that sheltered all these people in ATTICA 

 DATA for the present study are from the central Department of EMS & Na.H.O.C. archives

In the year 2016 they took place: more than 5000 records of emergency transportations from the above camps to Hospital through the Na.H.O.C. & EMS  

CONCLUSIONS:

  • The effect of migration problem in our country runs through every activity
  • EMS/NaHOC is responsible to manage the medical problems of the immigrants
  • This require resources from our country in a very difficult period to be available  
  • Although our country overcomes the present problems & reacts in the best practice 

 


Spyros PAPANIKOLAOU (ATHENS, Greece), Vasilis KEKERIS, Konstantina DIMITRIOU, Jimi JIANNOUSI
12:10 - 12:20 #10977 - OP043 Intoxications with prescription drugs at Tampere University Emergency department in 2014.
OP043 Intoxications with prescription drugs at Tampere University Emergency department in 2014.

Background: Intoxications with prescription drugs are a common burden at emergency departments (EDs). Mortality associated with intoxication has been increasing. Intoxications are a common way to commit suicide, especially among women. Our study aimed to evaluate intoxication patients` psychiatric history and other clinical features.

Material and methods: We identified all patients with ICD10- code TX36 from year 2014 at Tampere University ED.  We collected the data on age, gender, arrival time and date from hospital records. We also collected patient-specific data such as psychiatric diagnoses, previous psychiatric care and suicide attempts, alcohol and/or drug consumption, difficulties in life (with relationships, money, work or with own or relatives` health) and somatic symptoms.

Results: There were a total of 372 patients with a slight female predominance (51,6 %).The median age was 38 years (1-92 years).  40% of cases arrived to ED between 6 p.m-12 p.m. The most used prescription drug was benzodiazepam (34%). 13% of patients had also used some type of illegal drug, for example cocaine, LSD and cannabis. Activated charcoal was given to 71 % of the patients. According to our data, 53% of intoxications were intentional/suicidal and in 18% of cases the feature of self-harm was not registered. 10% of patients had had one previous intoxication in the database of Tampere University Hospital during the previous two years, and 2% had had more than one intoxication during the same time. The most common difficulties in life were associated with interpersonal relationships (43%). 54% of the patients received psychiatric consultation and 66% were guided to psychiatric after-care.  The most common somatic complication of the intoxication was respiratory tract infection (7 %). Seven-day mortality was 0.8 % and one-year mortality 4.8 %.

Discussion: The results of our study were convergent with previous intoxication studies. Gastrointestinal decontamination was executed rarely but the number of complications, however, was low. This can be partly explained by effective and well-functioning treatment chains and settings. Understanding the associated features of intoxication patients is important for care guidance to these patients. As we could see in this study, many of the patients attempted suicide but only a minority of them were in danger of death.  These cases should be recognized as a cry for help. It is important for health care workers to identify high-risk patients and to guide them to psychiatric care as soon as possible, in order to prevent recurrent intoxications. This study shows that if the intoxication patient reaches the hospital, the prognosis is good. The mortality rate in this patient group is low.


Sini HEIKKONEN, Tiia MERKKINIEMI, Sami MUSTAJOKI, Sami PIRKOLA, Satu-Liisa PAUNIAHO (Tampere, Finland)
12:20 - 12:30 #11833 - OP044 BACLOFEN POISONING: AN EPIDEMIOLOGICAL RETROSPECTIVE STUDY IN A TUNISIAN INTENSIVE CARE UNIT.
OP044 BACLOFEN POISONING: AN EPIDEMIOLOGICAL RETROSPECTIVE STUDY IN A TUNISIAN INTENSIVE CARE UNIT.

  


Ben Jazia AMIRA, Fatnassi MERIEM, Khzouri TAKOUA, Khelfa MESSOUDA, Aloui ASMA (Tunis, Tunisia), Fradj HANA, Blel YOUSSEF, Brahmi NOZHA
12:30 - 12:40 #11851 - OP045 Pediatric emergency department visits due to acute ethanol intoxication.
OP045 Pediatric emergency department visits due to acute ethanol intoxication.

Background: Alcohol is one of the most frequently abused drugs. Alcohol exposure of pediatric population is gradually increasing all over the world thus leading to acute alcohol intoxication and its consequences. 

Objective: The aim of this study was to describe presentations and analyze demographic, clinical and laboratory characteristics of pediatric patients presented to the pediatric emergency department with acute ethanol intoxication.

Methods: We conducted a retrospective review of pediatric patients, who presented to a pediatric emergency department with any complaint and had serum ethanol level determined between January 2006 and December 2016. Patients with serum ethanol level below 50 mg/dL, patients with insufficient data and patients older than 18 year-old were excluded from analyses.

Results: Serum ethanol levels were determined for 917 patients. Among these, 229 patients were tested positive for alcohol abuse having serum ethanol levels >50 mg/dL. Nine patients were excluded because of having insufficient data so a total of 220 patients (Male 128; female 92) were included in the study. 53% patients were brought to the emergency department by emergency medical services. Mean age was 16.0±1.6 years. Most frequent complaints at presentation were decreased level of consciousness (29.5%, n=65), nausea/vomiting (21.8%, n=48) and trauma (14.1%, n=31). The median Glasgow Coma Score on admission to the emergency department was 15.  Only 5 patients had GCS ≤8. Minor injuries were identified in vast majority of patients with trauma. Most common injury type was falls (5.5%, n=12). 11.8% (n=26) patients consumed alcohol as part of a suicidal attempt. Serum ethanol level ranged between 50.8-341.2 mg/dl (mean: 157.9±57.9 mg/dl).  63% (n=140) patients had blood gas analysis. Among these 68.6% (n=96) had hyperlactinemia. 207 patients had biochemical investigations, which revealed abnormal kidney functions in 20.8% (n=43). Likewise, 19% (n=39) had hypokalemia (<3.4 mEq/L) while 17.6% (n=36) had hypophosphatemia (<2.7 mEq/L). None of the patients had hypoglycemia. However, 51.9% (n=95) had mild hyperglycemia (100-200 mg/dL). Blood glucose level and pH were correlated with serum ethanol levels (p=0.007, R2=0.053 and p=0.008, R2= 0.038, respectively). Vast majority of the patients (94%) received treatment in the pediatric emergency department.

Discussion: Acute alcohol intoxication in pediatric population is a preventable emerging problem. It is important to recognize that hyperlactatemia, hypokalemia, hypophosphatemia, mild hyperglycemia and abnormal kidney functions are common biochemical findings in children with acute ethanol intoxication. 


Damla HANALIOĞLU (Ankara, Turkey), Ahmet BIRBILEN, Aslı PINAR, Filiz AKBIYIK, Ozlem TEKSAM
Kokkali
14:10

"Monday 25 September"

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A23
14:10 - 15:40

Geriatric (Cutting Edge)

Moderators: Mehmet Akif KARAMERCAN (Chair of EuSEM Research Committee) (ANKARA, Turkey), Pr Christian NICKEL (Vice Chair ED Basel) (Basel, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
14:10 - 14:40 Implementation of a screening program for older patients visiting the Emergency Department; pitfalls and opportunities. Simon. P. MOOIJAART (Internist-geriatrician) (Speaker, LEIDEN, The Netherlands)
14:40 - 15:10 How to geriatrisize your ED. Simon. P. MOOIJAART (Internist-geriatrician) (Speaker, LEIDEN, The Netherlands)
15:10 - 15:40 Delirium. Pr Christian NICKEL (Vice Chair ED Basel) (Speaker, Basel, Switzerland)
Trianti Hall

"Monday 25 September"

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B23
14:10 - 15:40

Resuscitation (How To)

Moderators: Tobias CRONBERG (Sweden), Othon FRAIDAKIS (Greece)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
14:10 - 14:40 To intubate or not to intubate during cardiac arrest. Clifton CALLAWAY (Speaker, Pittsburgh, PA, USA)
14:40 - 15:10 Glucose and Insulin during cardiac arrest. Roman SKULEC (Deputy head for research and science) (Speaker, Kladno, Czech Republic)
15:10 - 15:40 33°C or 36°C after resuscitation from cardiac arrest? Wilhelm BEHRINGER (Chair) (Speaker, Vienna, Austria)
Mitropoulos

"Monday 25 September"

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C23
14:10 - 15:40

Ultrasound (How to)
"Breaking the waves, new ways to use ultrasound in the ED"

Moderators: Gregor PROSEN (EM Consultant) (MARIBOR, Slovenia), Senad TABAKOVIC (Medical director emergency department) (Zürich, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
14:10 - 14:40 How ultrasound is going to influence decision making in the future. Eftychia POLYZOGOPOULOU (ASSISTANT PROFESSOR OF EMERGENCY MEDICINE) (Speaker, ATHENS, Greece)
14:40 - 15:10 New ways to use ultrasound in the ED. James CONNOLLY (Consultant) (Speaker, Newcastle-Upon-Tyne)
15:10 - 15:40 How to teach ultrasound in the future. Gregor PROSEN (EM Consultant) (Speaker, MARIBOR, Slovenia)
Banqueting Hall

"Monday 25 September"

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D23
14:10 - 15:40

YEMD - How to communicate in the ED

Moderators: Roberta PETRINO (Head of department) (Italie, Italy), Basak YILMAZ (Faculty) (BURDUR, Turkey)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
14:10 - 14:30 How to communicate with other clinics. Oktay ERAY (Speaker) (Speaker, Antalya, Turkey)
14:30 - 14:50 How to communicate with hospital management. Greg HENRY (Speaker, USA)
14:50 - 15:10 How to please patients and still practice good medicine. Dr Atriham ADAN (Medical Director, Emergency Department) (Speaker, Houston Texas - USA, USA)
15:10 - 15:30 How to build great ED staff. Roberta PETRINO (Head of department) (Speaker, Italie, Italy)
Skalkotas

"Monday 25 September"

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E23
14:10 - 15:40

Paediatric
Debate time

Moderators: Mark LYTTLE (Bristol, United Kingdom), Itai SHAVIT (Pediatric Emergency Physician) (Haifa, Israel)
Coordinators: Said HACHIMI-IDRISSI (Coordinator, GHENT, Belgium), Said HACHIMI-IDRISSI (head clinic) (Coordinator, GHENT, Belgium)
14:10 - 14:40 Fluid resuscitation in sick children: Yes-No. Dr Thomas BEATTIE (Senior lecturer) (Speaker, Edinburgh, United Kingdom)
14:10 - 14:40 Fluid resuscitation in sick children: Yes-No. Dr Ruth FARRUGIA (Paediatrician) (Speaker, Malta, Malta)
14:40 - 15:10 Tranexamic Acid in trauma resuscitation: Yes-No. David WALKER (Speaker) (Speaker, New York, NY, USA)
14:40 - 15:10 Tranexamic Acid in trauma resuscitation: Yes-No. Said HACHIMI-IDRISSI (head clinic) (Speaker, GHENT, Belgium)
15:10 - 15:40 Flumazenil for benzodiazepine overdose: Yes-No. Dr Cathelijne LYPHOUT (Consultant in EM) (Speaker, Ghent, Belgium)
15:10 - 15:40 Flumazenil for benzodiazepine overdose: Yes-No. Lisa AMIR (Speaker, Israel)
MC-3

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F23
14:10 - 15:40

Free Papers Session 6

Moderators: Felix LORANG (Consultant) (Erfurt, Germany), Dr Anastasia SFAKIOTAKI (Emergency Physician) (Melbourne, Australia)
14:10 - 14:20 #10117 - OP046 Differences in the use of skull radiography in children with minor head trauma.
OP046 Differences in the use of skull radiography in children with minor head trauma.

Background: Minor head trauma is a major cause of emergency department visits. Head computed tomography (CT) is the reference standard for the emergency assessment of head trauma. A recent multicentre study of Research in European Pediatric Emergency Medicine (REPEM) network demonstrated that 30% of patients with a minor head trauma (MHT) underwent skull radiography (SR).

Objective: Describe the practice variation in the use of SR for MHT in a group of hospitals affiliated to REPEM.

Design/Methods: Subanalysis of a multicenter retrospective study, including 15 hospitals from 9 European countries. Patients up to 18 years with MHT, defined by Glasgow Coma Scale score (GCS) 14-15, evaluated in years 2012, 2013 and 2014 were included. Pediatric Emergency Care Associated Research Network (PECARN) rules were considered the standard to assess differences in management and to stratify the risk for clinically important Traumatic Brain Injury (ciTBI).

Results: In the main study 13.266 patients (GCS 13-15) were included and 10.109 (76.8%) patients had MHT. The prevalence of ciTBI was 79/10109 (0.77%). SR was performed in 2.762 (27.3%) patients. The rate of SR varied between centres from 0.42% to 92% (figure 1).
Fifty-four (1.96%) had a skull fracture in the SR. In 27 (50%) a head CT confirmed a skull fracture or documented an intracranial lesion. Thirteen (48.1%) patients with skull fracture had other intracranial findings while 14 (51.9%) children had an isolated displaced skull fractures.
Three (11.1%) patients required surgery, due to intracranial lesions.
In 27 (50%) patients, the head CT did not demonstrate any fracture or intracranial lesion.
Twenty-one (77.8%) true positive patients would be classified as intermediate or high risk for ciTBI according PECARN criteria.
Focusing on children determined as low risk for ciTBI according to PECARN rules, SR was performed in 1.933 (28.9%) patients, and demonstrated a fracture in 12 (0.62%) patients. Three (0.16%) patients had an associated intracranial lesion.
Factors associated with the use of SR were grouped as intermediate or high risk for ciTBI according to PECARN rules and isolated scalp hematoma.

Conclusion(s): Although the low diagnostic value does not justify its use, SR is frequently ordered in management of MHT patients in a representative group of pediatric emergency department of the REPEM. We demonstrated a wide variation in the use of SR. These differences are mainly to be due to local or national guidelines and consolidated practices more than lack of adherence to validated prediction rules.


Dr Roberto VELASCO (Laguna de Duero, Spain), Niccolo PARRI, Carmel MOORE, Zsolt BOGNAR, Federica D'ELIA, Özlem TEKSAM, Santiago FERNANDEZ, Liviana DA DALT, Eveline SNOECK, Merel BROERS, Ricardo FERNANDES, Anaida OBIETA, Maider ALCALDE, Javier GONZALEZ, Sergi PIÑOL
14:20 - 14:30 #10905 - OP047 Cervical spine stabilisation in pediatric major trauma: a questionnaire of current practice.
OP047 Cervical spine stabilisation in pediatric major trauma: a questionnaire of current practice.

Background

Cervical spine (C-spine) injuries in pediatric trauma are rare (0-2%)1, but can cause long-term morbidity. Recent Advanced Paediatric Life Support (APLS) guidance1 updated advice on management of suspected C-spine injury, not advocating routine use of hard collars. There are minor differences within existing national guidance on the same subject [National Institute for Health and Care Excellence (NICE)2, Joint Royal Colleges Ambulance Liaison Committee (JRCALC)3, Advanced Trauma Life Support (ATLS)4]. This study was undertaken to formally understand observed variations in C-spine stabilisation for pediatric trauma in the East of England (EoE) Trauma Network. 

 

Methods

An online questionnaire was sent to members of the EoE Trauma Network.  Respondents were presented with five hypothetical scenarios, reflecting changes in guidance, summarised as follows; 1) 4 year old (yr), high-speed motor vehicle collision, intubated, 2) 9 yr, 2 metre fall, GCS 14, chest pain, 3) 7 yr, bicycle collision, C-spine tenderness, for transfer to CT, 4) 6 yr, 4 step fall, GCS 13, combative, 5) 3 yr, rollover motor vehicle collision, asymptomatic.

Respondents chose whether C-spine protection was required followed by the type of protection required [‘Manual in-line stabilisation’ (MIS), ‘Collar’ or ‘Blocks and tape’ (B&T)] and ‘No protection required’. 

 

Results

A total of 163 responses were received from October 2016 to February 2017, mainly from paramedics (64%, 105/163) and 13% (21/163) from doctors.

  1. 77% (124/162) were unaware of recent changes in APLS guidance.
  2. The majority thought stabilisation was required in scenarios 1 to 4 [97% (161/166), 77% (130/168), 96% (158/164) and 82% (136/166) respectively]. However, opinion was divided in scenario 5 with 50% (81/162) choosing to stabilise, and 50% (81/162) otherwise. 
  3. The chosen method of stabilisation also varied, notably in scenario 2 [MIS; 44% (57/130), collar; 20% (26/130), B&T; 36% (47/130)]. Few chose collar for a combative child [scenario 4; 8% (11/136)].
  4. Of 666 total responses, collars were chosen least often [18% (118/666)], and MIS and B&T were selected equally [41% (274/666)].

 

Conclusions

The results suggest varying practice in C-spine stabilisation in the region, possibly reflecting variation in national guidelines. Encouragingly, appropriate protection was used majority of the time. Despite the limitations of this survey, it provides preliminary evidence of inconsistent practice, and hence requirement for clearer guidance and education.  More studies are needed to validate these findings, and ascertain whether they are representative of a national issue.


Lucy CROSSMAN (Cambridge, United Kingdom), Shruti AGRAWAL, Helen BAILIE, Khurram IFTIKHAR
14:30 - 14:40 #10956 - OP048 How well do vital signs predict serious illness in children?
OP048 How well do vital signs predict serious illness in children?

Introduction 

Vital signs are commonly measured during the first clinical assessment at the emergency department (ED). Usually, healthcare workers judge these physiologic measurements based on existing reference ranges and values below or above the pre-specified cut-offs are interpreted as abnormal. Many different vital signs reference ranges exist for use in children, but their diagnostic value is uncertain. Therefore, the aim of this study is to determine the diagnostic value of commonly used heart rate and respiratory rate reference ranges for the recognition of serious illness in children at the ED.

 

Methods

We assessed commonly used paediatric reference ranges for heart rate and respiratory rate, including those from guidelines, textbooks, medical literature and those provided in triage systems or early warning scores. The analysis is based on a observational cohort of children under 16 years of age, presenting to the ED of a university hospital in the Netherlands (2009-2012). Nurses routinely recorded patient data, vital signs and patient destination in the electronic health record. Missing vital signs were imputed 10 times using a multiple imputation approach. In a descriptive analysis we explored differences between the age-classification and cut-off values of the different reference ranges. Moreover, we assessed the diagnostic accuracy of these reference ranges for serious illness in children, defined as the need for ICU admission or hospital admission immediately after the ED visit

 

Results 

In our cohort, 15,099 children attended the ED during the study period, of whom 314 (2.1%) were admitted to ICU and 2681 (17.8%) to hospital. We identified 11 commonly used paediatric reference ranges for heart rate, respiratory rate, or both. These showed a large variation in age classification and corresponding cut-off values. Application of the different reference ranges in our cohort classified 2.4% to 58.0% of heart rate and 1.0% to 61.4% of respiratory rate values as abnormal. None of the individual vital signs had both a high sensitivity and a high specificity to detect serious illness in children, but the trade-off was very different for each of the reference ranges. Abnormal heart rate had a sensitivity ranging from 0.13 to 0.76 and a specificity ranging from 0.42-0.98 for ICU admission. For hospital admission, sensitivity ranged from 0.06 to 0.72 and specificity from 0.45 to 0.98. The diagnostic accuracy of respiratory rate also had a wide range, with sensitivity 0.05 to 0.69 and specificity 0.39 to 0.99 for ICU admission and sensitivity 0.02 to 0.68 and specificity 0.39 to 0.99 for hospital admission.

 

Conclusion

Several vital sign reference ranges for children exist and differences are large. It is important to be aware whether a certain reference range is better at ruling-in or ruling-out serious illness. Future research should aim at optimizing the cut-off of individual vital signs to improve existing reference ranges for children at the ED.


Joany ZACHARIASSE (Rotterdam, The Netherlands), Nienke HAGEDOORN, Henriëtte MOLL
14:40 - 14:50 #11026 - OP049 The value of routine blood pressure measurement in children at the emergency department: a prospective observational study.
OP049 The value of routine blood pressure measurement in children at the emergency department: a prospective observational study.

Introduction

Blood pressure measurement is recommended in children at the emergency department (ED) because low blood pressure is considered a marker of serious illness. However, blood pressure measurement is time consuming and a burden for (young) children. Moreover, different reference values are available and little evidence exists about the diagnostic value of low blood pressure in children. This study aims to identify lower reference values for systolic blood pressure and to investigate the diagnostic value of routine blood pressure in addition to heart rate in children at the ED.

 

Methods

A systematic review was performed to define age-specific cut-off points for low blood pressure. Secondly, we used blood pressure cut-offs from two well-known international guidelines (APLS and PEWS) in a prospective cohort of children attending a university ED (2009-2013) in the Netherlands. To investigate the diagnostic value for these two blood pressure cut-offs, we performed multivariable logistic regression to assess the association of abnormal blood pressure with serious illness, adjusted for abnormal heart rate. Sensitivity and specificity for serious illness (hospital or ICU admission) according to abnormal blood pressure defined by the APLS and PEWS were calculated. To assess the additional value for heart rate, sensitivity and specificity were computed for tachycardia and for patients who had both tachycardia and abnormal blood pressure according to the two cut-offs.

 

Results

18 articles and 11 guidelines reported reference ranges. Only one guideline cited literature references. There was a large variation between the different age-related cut-offs for hypotension (differences ranging from 15 to 30 mmHg in age groups). In the observational study, 5467 children had complete data of blood pressure and heart rate. Frequency of ICU- and hospital admission was 5.5% and 34.7%, respectively. Abnormal blood pressure was significantly associated with hospital admission when adjusted for heart rate based on APLS (OR 1.32 95%CI 1.17–1.48) or based on PEWS (OR 1.76 95%CI 1.57–1.98). Similar associations were found with ICU admission. Abnormal blood pressure according to the APLS showed moderate sensitivity (67%; 61%) and low specificity (43%;45%) for ICU- and hospital admission. The PEWS demonstrated low sensitivity (55%;44%) and moderate specificity (64%; 68%). Tachycardia had low sensitivity (37%;30%) and high specificity (81%;85%) for ICU- and hospital admission. When combining tachycardia and abnormal blood pressure, the APLS showed high specificity (88%; 90%) and low sensitivity (21%;14%). The PEWS showed similar results.

 

Conclusion

Clinical references for blood pressure show large differences and are mostly not evidence based. Abnormal blood pressure showed an association with serious illness at the ED, but its diagnostic value is uncertain. However, the combination of tachycardia and abnormal blood pressure appears to be good at ruling-in serious illness. 


Nienke HAGEDOORN (Rotterdam, The Netherlands), Joany ZACHARIASSE, Henriëtte MOLL
14:50 - 15:00 #11068 - OP050 Are procalcitonin, C-reactive protein and absolute neutrophil count useful for predicting invasive bacterial infection in neonates under 21 days old with fever without source?
OP050 Are procalcitonin, C-reactive protein and absolute neutrophil count useful for predicting invasive bacterial infection in neonates under 21 days old with fever without source?

Background: neonates with fever without source (FWS) present a higher prevalence of invasive bacterial infection (IBI) than older infants. For this reason, it has been universally recommended performing a lumbar puncture and the admission with antibiotic treatment for any febrile neonate, even for those who are well-appearing. The “Step-by-Step” approach uses the 21-days-old cut-off point to identify high-risk patients. Our objective was to analyze the performance of the procalcitonin (PCT), C-reactive protein (CRP) and absolute neutrophil count (ANC) to identify IBIs among well-appearing neonates ≤21 days old with FWS.

Methods: a prospective registry-based cohort study including all the infants ≤90 days old attended in the Pediatric Emergency Department of a tertiary teaching hospital between September 2008 and August 2016 with FWS. We compared the prevalence of IBI (isolation of a pathogen bacterium in blood or cerebrospinal fluid) between those well-appearing patients ≤21 days old and >21 days old without leukocyturia in two groups: those with altered blood tests (PCT ≥0.5 ng/mL, CRP >20 mg/L or ANC >10000/mcL) and those with normal blood tests. We excluded those patients in whom the value of any of the three blood tests, the urine dipstick result or the blood culture result was not available.

Results: we included 1,762 of the 1,970 infants ≤90 days old with FWS attended (89.4%). Of them, 1,358 (77.0%) infants were well-appearing and had no leukocyturia in the urine dipstick. PCT, CRP and ANC values were normal in 126 of the 178 infants ≤21 days old (76.7%) and in 956 of the 1,180 infants > 21 days old (81.0%).

Prevalence of IBI in infants ≤21 days old was 3.2% among those with normal blood tests (vs 0.1% in infants >21 days old; OR 31.31 [IC 95%: 3.28-741.52]) and 5.7% among those with any of the three blood tests altered (vs 4.9% in infants >21 days old; OR 1.19 [IC 95%: 0.25-4.83]). Two of the four well-appearing infants ≤21 days old with normal blood tests who had an IBI were diagnosed with a bacterial meningitis.

Sensitivity and specificity of the three blood tests for identifying IBIs were 42.9% (15.8-75.0%) and 71.3% (64.2-77.6%), respectively in infants ≤21 days old and 91.7% (64.6-98.5%) and 81.8% (79.4-83.9%), respectively in infants >21 days old.

Discussion: PCT, CRP and ANC do not have a good performance to identify febrile infants less than 21 days old at low risk for IBI. In contrast to older infants, these tests cannot be used to identify patients suitable for a less aggressive management. Accordingly, neonates under 21 days old with FWS must be admitted with empiric antibiotic treatment after performing a lumbar puncture, regardless the general appearance and the results of the blood tests.


Borja GOMEZ (Barakaldo, Spain), Haydee DIAZ, Alba CARRO, Javier BENITO, Santiago MINTEGI
15:00 - 15:10 #11306 - OP051 Antibiotic prescription in children with respiratory tract infections at EDs in The Netherlands.
OP051 Antibiotic prescription in children with respiratory tract infections at EDs in The Netherlands.

Introduction

Fever is the main presenting symptom of children presenting at paediatric emergency departments (EDs) in Europe, with a majority related to respiratory tract infections (RTI’s). Despite a low rate of bacterial infections (5 – 10% of febrile children), we observe antibiotic prescription rates of 40-56% in children with RTI’s, with high variability among European EDs. This study aims to evaluate the association between clinical characteristics and antibiotic prescription rates in children under five with suspected lower respiratory tract infections at 6 Dutch EDs.


Methods

Prospective collected data of a multicentre study in 6 paediatric EDs in The Netherlands, both teaching and non-teaching. The population consisted of children aged 1 month to 5 years presenting at the ED with fever and cough or dyspnoea. We computed a risk profile for bacterial infection based on clinical characteristics, using a clinical prediction rule (Feverkidstool). Variation in risk profile and antibiotic prescription rate were assessed and associations tested.


Results

Results are based on 206 patients, 63% male, median age 16 months (IQR 7 – 32m). Median predicted risk of a bacterial infection according to the Feverkidstool was 9% (IQR 9 – 17%), ranging between centres from 5 – 15%. Overall antibiotic prescription rate was 42% (range 24 – 60% between centres). Children with a higher risk profile had a significantly higher prescription rate (Nagelkerke’s R2=23%). There was no association between prescription rate and centre. When stratified by clinical profile, antibiotic prescription rate was 13% in low-risk patients (predicted risk 0-5%), 34% in medium-risk patients (predicted risk 5-10%) and 65% in high-risk patients (predicted risk >10%).


Discussion

Antibiotic prescription rates are high among children with respiratory tract infections with variable rates among 6 Dutch EDs. Variability among centres is mainly explained by risk profile. Given the nature of lower respiratory tract infections, watchful waiting and follow-up in low and medium-risk patients could add to a reduction in antibiotic prescriptions.


J.s. VAN DE MAAT (Rotterdam, The Netherlands), D. NIEBOER, A.m.c. VAN ROSSUM, F.j. SMIT, J.g. NOORDZIJ, G. TRAMPER, C.c. OBIHARA, A. VAN WERMESKERKEN, G.j.a. DRIESSEN, J. PUNT, H.a. MOLL, R. OOSTENBRINK
15:10 - 15:20 #11489 - OP052 INTRANASAL KETAMINE FOR PERIPHERAL VENOUS ACCESS IN PEDIATRIC PATIENTS: A RANDOMIZED DOUBLE BLIND AND PLACEBO CONTROLLED STUDY.
OP052 INTRANASAL KETAMINE FOR PERIPHERAL VENOUS ACCESS IN PEDIATRIC PATIENTS: A RANDOMIZED DOUBLE BLIND AND PLACEBO CONTROLLED STUDY.

Objectives: To verify the efficacy of intranasal ketamine as sedative agent for venous access in children.
Method: Randomized, double blind, placebo controlled study conducted at ER Hospital de Clínicas de Porto Alegre (Brazil) between November 2015 and August 2016. Children needing venous access were randomized to receive intranasal ketamine (4mg/Kg) or normal saline solution (Placebo group). Groups were compared regarding the time for venous access, facility for performing the procedure, adverse events, disturbances in vital signs and perception of the accompanying adult. The study was approved by the Local Ethics Committee.

Results: 39 children (21 Ketamine; 18 Placebo) were included without differences regarding to age, sex, weight, reason for hospitalization and professional experience. The median age was similar (19.8 x 15.8 months), as well as the median weight (10.0 x 11.3Kg). Ketamine reduced the length for venous access (23.0 x 67.5 seconds; p=0.01), and facilitated the procedure (p=0.00009). Ketamine induced sleepiness 15 minutes after its administration (p=0.003) and reduced the number of people for the child’s restraint (p=0.025). No difference was verified between groups regarding adverse effects or vital signs disturbance ́s. Side effects were observed in 29% of the children in the Ketamine group and 17% in the Placebo group, irritability being the most common for both. The accompanying adult reported that 81% of children in ketamine group were calm and quiet (p=0.0003).

Conclusions: Intranasal ketamine (4mg/Kg) reduces the time for venous puncture, facilitates the procedure to the nurse, decreases the number of people involved and provides a tranquil environment with low risk.


Patricia LAGO (PORTO ALEGRE, Brazil), Joao Carlos SANTANA
15:20 - 15:30 #11541 - OP053 Optic nerve sheath diameter measurement: a means of detecting increased ICP in traumatic and non-traumatic pediatric patients.
OP053 Optic nerve sheath diameter measurement: a means of detecting increased ICP in traumatic and non-traumatic pediatric patients.

Introduction: Increased Intracranial Pressure (IIP) is a highly clinical mortality condition, which can be caused by various causes. It should be diagnosed rapidly, and its treatment should be done timely and correctly in emergency units. The procedures performed for the purpose of diagnosing and determination of etiology in patients with IIP are either invasive or cause radiation exposure. In this study, we aimed to determine the benefit of measurement of the optic nerve sheath diameter (ONSD) by ultrasonography (US) and power of the test in the evaluation of IIP.

Materials and Methods: After the primary treatment of the patient who was brought to our pediatric emergency department, transorbital ultrasonography was applied in the supine and neutral position as his/her eyes closed. Sonographic ONSD evaluation was performed using a SonoSite Edge ultrasound device with 6–13 MHz linear probe. The diameter of the optic nerve, which appeared as a hypoechoic two-sided line at a depth of 3 mm of globes which is determined as more sensitive to IIP alteration, was measured and recorded in both longitudinal and transverse sections.

Findings: Fifty-seven cases with IIP suspicion brought to our unit (31 males; 138 ±56 months old) and 35 controls (17 males; 151± 45 moths old)  were included in the study between June 2015 and December 2016. Thirty-one cases (54%) were trauma cases with the high probability of clinical signs of IIP. Others had headache, vomiting, altered consciousness, seizures. Eight of our patients had GCS <= 8. One patient died and 16 children were admitted to our intensive care unit. 19 of our patients were treated with anti-edema treatment. The ONSD value of the 38 patients without brain edema on CT scan was 4.8 ± 0.05 mm (Processing time: 2.8 ± 1 min). The ONSD of those with brain edema was 5.5 ± 0.07 mm (Processing time: 2.0 ± 1 min). The mean ONSD of all patients (5.0 ± 0,07 mm) showed significantly increased compared with the controls (3,9 ± 0,02 mm) (p<0.01). The ideal cut-off value of ONSD was found to be 4.9 mm when the cerebral edema detected in the CT scan was accepted as a reference (Sensitivity 84.2% and specificity 63.2%). Six patients had optic disc elevation (The median ONSD was 6 mm). The CT scan of all of these patients was compatible with brain edema.

Conclusions: CT examination and fundoscopy for diagnosing IIP are useful methods for middle/late stages of the IIP syndrome. As ONSD begins to expand within minutes when intracranial pressure begins to increase, ONSD measurement may be more sensitive in the acute stage and guide patient management in case of clinical suspicion of IIP.


Ozlem TOLU KENDIR, Hayri Levent YILMAZ (Adana, Turkey), Tugsan BALLI, Ahmet Kagan OZKAYA, Sinem SARI GOKAY
15:30 - 15:40 #11676 - OP054 EFFECTS OF A CLINICAL PATHWAY ON ANTIBIOTIC PRESCRIPTIONS FOR PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIA.
OP054 EFFECTS OF A CLINICAL PATHWAY ON ANTIBIOTIC PRESCRIPTIONS FOR PEDIATRIC COMMUNITY-ACQUIRED PNEUMONIA.

Background and aims: Italian pediatric antimicrobial prescription rates are among the highest in Europe. It is essential to identify efficient measures to improve antimicrobial stewardship (AS) programs. Since Clinical Pathways (CPs) have proven a promising tool to reduce antibiotic prescriptions in primary care and in-hospital settings, we hypothesized that their implementation in the Padua University Hospital Pediatric Emergency Department (PED) would decrease overall prescription of antibiotics, especially broad-spectrum (BS), for common infectious diseases such as Community-acquired pneumonia (CAP). 

Materials and methods: CP was implemented at the Department for Woman and Child Health of Padua on 01/10/2015. This is a pre-post quasi-experimental study comparing the 6-month period prior to CP implementation (baseline period: 15/10/2014-15/04/2015) and during the 6 months after intervention (post intervention: 15/10/2015-15/04/2016). We collected data from children aged 3 months -15 years diagnosed with CAP. We assessed differences in various measures of antibiotic prescription between pre and post periods including rates, breadth of spectrum, duration of therapy and, for inpatients, length of hospital stay. Chi-square, Fisher’s exact test and Wilcoxon rank sum test were used as appropriate. 

Results: 120 pre and 86 post-intervention clinic visits were associated with CAP. In regards to outpatients, we observed a decrease of BS regimens (50% vs. 26.8%, p=0.0215), in particular macrolides, and an increase of narrow-spectrum ones (amoxicillin). Children received less antibiotics (median DOT from 10 to 8, p=0.0001) for fewer days (median LOT from 10 to 8, p=0.0001). Physicians prescribed a narrow- spectrum monotherapy more frequently than BS combination therapy (DOT/LOT ratio 1.157 vs. 1.065). No difference in treatment failure incidence was reported before and after the implementation (2.3% vs. 11.8%, p=0.2862). Among inpatients we also noted a decrease in BS regimens (100% vs. 66.7%, p=0.0238) and the introduction of narrow-spectrum regimens (0% vs. 33.3%, p=0.0238). Admitted patients received less antibiotics (median DOT from 18.5 to 10, p=0.004), while there was no statistical difference in LOT (median LOT from 11 to 10, p=0.0629). In particular, children received a notably lower amount of BS days of therapy (median bsDOT from 17 to 4.5, p <0.001). No difference in treatment failure was reported before and after CP implementation (16.7% vs. 15.4%, p >0.999).

Discussion: Our study showed sustained changes in physicians' prescribing behaviors for CAP after implementation of a clinical pathway. Prescribing changes for CAP included an immediate increase in amoxicillin prescriptions with a concomitant reduction of BS antibiotic prescriptions, use of combination therapy and duration of treatment for CAP indicates effectiveness of CP for AS in this setting. 


Daniele DONÀ (Padua, Italy), Silvia ZINGARELLA, Andrea GASTALDI, Rebecca LUNDIN, Anna Chiara FRIGO, Silvia BRESSAN, Marco DAVERIO, Rana HAMDY, Theoklis ZAOUTIS, Liviana DA DALT, Carlo GIAQUINTO
Kokkali
15:45

"Monday 25 September"

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PH3 - S3
15:45 - 16:05

E-Poster Highlight Session 3 - Screen 3

15:45 - 15:50 #10482 - Increased risk of hypothyroidism in patients with acute anticholinesterase pesticide poisoning: a nationwide population-based cohort study.
Increased risk of hypothyroidism in patients with acute anticholinesterase pesticide poisoning: a nationwide population-based cohort study.

Objectives: Previous animal studies reported that acute anticholinesterase pesticide (organophosphate and carbamate) poisoning (ACPP) may affect thyroid hormones. There is no human study investigating the association of hypothyroidism and ACPP, and therefore we conducted a retrospective nationwide population-based cohort study to delineate this issue.

Methods: We identified 10372 ACPP patients and matched 31116 non-ACPP patients between 2003 to 2012 in a 1:3 ratio by index date from Taiwan’s National Health Insurance Research Database for this study. We compared cumulative incidence of hypothyroidism between two cohorts by following up until 2013. Independent predictors for hypothyroidism were also investigated.

Results: In total, 75 (0.72%) ACPP patients and 184 (0.59%) non-ACPP patients were diagnosed with hypothyroidism during follow-up. Cox proportional hazard regression analysis showed that ACPP patients had higher risk for hypothyroidism than non-ACPP patients (adjusted hazard ratio: 1.47, 95% confidence interval [CI]: 1.11-1.95) by adjusting age, sex, hypertension, malignancy, liver disease, renal disease, atrial fibrillation and flutter, thyroiditis, goiter, endocrine disorder, and mental disorder. Stratified analysis showed that ACPP patients had higher risk for hypothyroidism than non-ACPP patients in the subgroups of 40-64 years, female, past history of goiter, and follow-up of < 1 month. ACPP patients without atropine treatment had higher risk for hypothyroidism than non-ACPP patients (incidence rate ratio: 1.66, CI: 1.20-2.30), but ACPP patients with atropine treatment did not. Female gender, malignancy, renal disease, thyroiditis, goiter, mental disorder, and ACPP without atropine treatment were independent predictors for hypothyroidism in the all patients.

Conclusions: ACPP might increase the risk for hypothyroidism. We suggested that early evaluation of thyroid function for ACPP patients is needed, especially in the patients of 40-64 years, female, and past history of goiter. Further studies are warranted for the detail mechanisms.

 


Hung-Sheng HUANG (Taiwan, Taiwan), Chien-Chin HSU, Chung-Han HO, Chien-Cheng HUANG
15:50 - 15:55 #11060 - Prehospital abdominal ultrasound alters treatment decisions in a Dutch helicopter emergency medical service.
Prehospital abdominal ultrasound alters treatment decisions in a Dutch helicopter emergency medical service.

Background

Ultrasound plays a significant role in emergency medicine protocols worldwide. It has proven to be a valuable tool, especially in patients subjected to blunt abdominal trauma. In a prehospital setting, ultrasound of the chest, abdomen, and pericardium is considered a valuable addition to physical examination and it guides patient management. Nevertheless, recent reviews conclude that a positive contribution remains controversial. We aim to determine the impact of prehospital abdominal ultrasound on treatment decisions in a Dutch physician-staffed helicopter emergency medical service (HEMS).

Methods

We conducted a retrospective review of patients who underwent abdominal ultrasound examination from 1 January 2007 through 31 December 2016 performed by the HEMS of Nijmegen, The Netherlands. It services an area of 10.088 square kilometers inhabited by 4.5 million. Physicians record data on every scramble and patient treated in a dedicated electronic database. The retrieved data included patient demographics, type of incident, abdominal ultrasound findings, impact on treatment decisions, and the physicians’ narrative report. Detection of hemoperitoneum with ultrasound was compared to computed tomography (CT) scan and laparotomy. Outcome parameters were: impact of ultrasound on treatment decisions, incident types leading to ultrasound examination, and its performance.

Results

Of 17077 recorded scrambles and 8699 patients treated, 1583 underwent 1631 abdominal ultrasound examinations. Male to female ratio was 3.54:1. Most suffered from traffic accidents and falls from height. After eliminating missing data, 1539 examinations lead to 193 (12.5% - CI 10.8-14.2%) impacted treatment decisions. Alterations were related to information provided to the receiving hospital (40%); mode of transportation, including physicians escorting patients (29%); choice of receiving hospital (13%); fluid management (13%); converting to a ‘scoop-and-run’ strategy (2%); administrating or withholding drugs (1%). Sensitivity of prehospital abdominal ultrasound for hemoperitoneum was 31.3%, specificity 96.7%, and accuracy 82.1%.

Discussion

Ten years of data on prehospital abdominal ultrasound showed management alterations in 12.5% of cases. Although comparable studies are scarce, a similar study showed a significantly higher impact on patient management but had an entirely different design. Sensitivity is low, likely due to the prehospital setting with many detrimental environmental factors, high stress, and time pressure. Also, accumulation of intraperitoneal blood is time-dependent and will be negligible at first. Furthermore, CT detects small quantities of free fluid, also in the retroperitoneal space associated with pelvic injury. In conclusion, prehospital abdominal ultrasound in our setting alters patient management significantly. It, therefore, is a valuable tool in the Dutch HEMS setting, and probably beyond.


Rein KETELAARS, Jasper HOLTSLAG (Nijmegen, The Netherlands), Nico HOOGERWERF
15:55 - 16:00 #11487 - Evaluation of utilising Mental Health Nurses in the management of Ambulance Service patients experiencing a mental health crisis.
Evaluation of utilising Mental Health Nurses in the management of Ambulance Service patients experiencing a mental health crisis.

The aim of this evaluation was to explore the impact, views and experiences of implementing an on-going initiative in Yorkshire Ambulance Service (YAS), utilising specialist triage by mental health nurses in the YAS Emergency Operations Centre (EOC).

An exploratory evaluation involved interviews with a range of staff (n=12) and analysis of computer aided dispatch (CAD) data.

Preliminary impressions of the intervention derived from this evaluation indicate that the triage nurses are increasingly managing patient’s issues over the phone to deliver ‘hear and treat responses’, thereby reducing unnecessary ambulance dispatch and conveyance to ED. Specialist mental health triage appears to deliver benefits from a patient and organisational perspective. These include improved responses that meet the needs of ambulance service patients experiencing a mental health crisis, reduced usage of ambulance resources and reduced conveyance to ED where not wholly appropriate.

Initial implementation was conducted quite rapidly and the approach was still evolving at the time of the evaluation. Perceived effectiveness of the mental health nurse triage scheme is attributed to the nurses’ established contacts and their ability to communicate inter-professionally with staff in mental health services. Staff reported an enhanced awareness of mental health issues, as well as improved working relationships and morale amongst those directly involved in managing patient calls since the introduction of mental health nurses. Staff in the frequent caller programme acknowledged the role that the nurses play in helping to manage patients with complex mental health needs.

The majority of the 3983 calls triaged by the mental health nurses (April - December 2015) were from Advanced Medical Priority Dispatch System (AMPDS) card categories 23 (overdose/poisoning) and 25 (psychiatric/ suicide).  As the number of calls triaged increased over the nine month period, the proportion of card 23 and 25 calls decreased, with more calls originating from across 22 ‘other’ AMPDS card categories. Analysis of available computer aided dispatch (CAD) data indicates that rates for (a) ambulance dispatch and (b) total cases conveyed were lower for calls triaged by the mental health nurses.

Further evaluation and research is needed to examine this intervention in more detail, including service user experiences and cost-benefits of implementing a mental health triage nurse intervention.

Full report available at: https://www.shef.ac.uk/polopoly_fs/1.647212!/file/YAS_Mental_Health_Triage_Report.pdf


Andy IRVING (Sheffield, United Kingdom), Rachel O'HARA, Johnson MAXINE, Anglela HARRIS
16:00 - 16:05 #11678 - Seventy-two hour emergency department returns at the North Estonia Medical Centre.
Seventy-two hour emergency department returns at the North Estonia Medical Centre.

Backround: The North Estonia Medical Centre is one of the top health care providers in Estonia. Each year, around 145,000 patients receive specialist medical care, a total of 36,000 of them are assigned to the hospital`s 1200 beds. The annual volume in the emergency department (ED) is approximately 80,000 visits. The number of ED visitis is constantly increasing over the past years. The causes for unscheduled returns to the emergency department (ED) within 72 hours of discharge at our hospidal are unclear.

Objective: To determine rate, common initial presentation and cause of unscheduled emergency department return visits within 72 hours at the North Estonia Medical Centre.

Methods: The study was conducted between 1 September 2016 and 30 November 2016. Data were abstracted from hospital electronic patient records, abstracted data included variables related to patient information, reason for visit, injury/poisoning, diagnosis and medications. The previous care variable was revised to collect data that includes three types of return visits; scheduled, unscheduled returns that are unrelated to the initial visit and unscheduled return visits related to the initial visit. For revisited patients, we identified the cause of the revisit, changes in diagnosis and/or treatment, diagnosis mistakes,  and final destination of the patient.

Results: There were 806 patients who had at least one scheduled or unscheduled 72 h return visit to the ED. These 806 patients made a total of 1781 initial and return visits, which accounted of 9.55 percent of the total number (18,655) of ED visits during the studied period.  Unscheduled visits constitute broadly half of these visits, which is comparable rate to ohter similar studies conducted in Europe and North America. The 72-hour return for admission rate, which is considered to be more critical measure was up to one third of unscheduled visits.

Discussion: The revisit rate in our ED is similar to other hospitals in Europe and North America. A relatively high percentage of revisited patients require to be admitted to the hospital. Further data analysis is needed to identify factors associated with unscheduled 72 h returns in the ED to serve as a basis for development of interventions to decrease unscheduled returns and improve quality of care and safety of patients.

More detailed data will be presented in tables and graphs.


Liis ILMET (Tallinn, Estonia), Lauri KESKPAIK, Kristiina PÕLD
E-Poster Area

"Monday 25 September"

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PH3 - S1
15:45 - 16:05

E-Poster Highlight Session 3 - Screen 1

Moderators: Cornelia HÄRTEL (Medical Director of the ED, Consultant in EM, Director of Medical Education in EM) (STOCKHOLM, Sweden), Pr Riccardo PINI (Director, E.D. High Dependency Unit) (Florence, Italy)
15:45 - 15:50 #10962 - Patients with mild knee trauma in Emergency Department : Initial and 1 month after discharge evaluation.
Patients with mild knee trauma in Emergency Department : Initial and 1 month after discharge evaluation.

Background: Mild knee trauma is a common reason for consultation in Emergency Department (ED). The Ottawa Knee Rules are used to determine if X-rays of the knee should be performed to find a fracture. Apart from bone injury, ligament and meniscal injury should be investigated. The diagnosis of ligament and meniscal injury of the knee is essentially on the questioning that allows to appreciate the mechanism of the trauma. As well as the clinical examination of the knee which makes it possible to test ligament and meniscal structures. In practice, evaluation of a knee trauma in the acute phase is difficult because of the painful phenomena, the functional impotence and often incomplete questioning about the fall. The objective of this study was to evaluate the initial and 1-month management of patients who had consulted for mild knee trauma in ED in order to improve their initial and post-discharge overall management. Methods: We conducted a prospective study in the Lariboisière hospital ED in Paris between February 2016 and June 2016. The patients included were any patient consulting for a mild knee trauma in ED who did not require initial surgical management or hospitalization. Patients had an initial evaluation when they were in the ED and were contacted by phone 30 days after discharge from ED for a final evaluation. The primary outcome was diagnostic concordance between initial diagnosis in the ED and final diagnosis 30 days after discharge from ED. Results: During the study period, 70 patients were analyzed. They came by their own means to the ED in 63% of the cases, following a fall (78%) with direct (50%) or indirect (50%) shock. Knee testing was performed in 69% of patients with laxity in 13% of cases. The only radiological examination performed was a radiograph of the knee in 98% of the patients. Emergency diagnosis was contusion (41.5%), ligament injury (47.1%), and meniscal injury (7.1%). Some patients were discharged from the ED with an external MRI prescription (51.4%). A clinical revaluation with a general practitioner, traumatologist or orthopedic surgeon was requested for 92.8% of patients. Finally, 75% patients were revaluated and 24% completed knee MRI. Knee MRI was justified for 60% patients showing ligament or meniscal injury. Thirty days after discharge from ED, diagnostic concordance was 52% for knee contusions, 27% for meniscal injury and 17% for ligament injury. Conclusion: Diagnostic concordance between initial diagnosis and diagnosis 30-days after discharge from ED was poor. A systematic revaluation could be beneficial for patients consulting with mild knee trauma in ED, especially when ligament or meniscal injury is suspected. The prescription of a MRI could be useful after discharge from ED if meniscal or ligament injury can not be eliminated.


Erwin HANSCONRAD (Vincennes), Anthony CHAUVIN, Patrick PLAISANCE
15:50 - 15:55 #11101 - Impact of a Antimicrobial Stewardship Program to optimize antimicrobial usage at Emergency Department of an university hospital.
Impact of a Antimicrobial Stewardship Program to optimize antimicrobial usage at Emergency Department of an university hospital.

Background: Antibiotic overuse has enabled growing rates of antimicrobial resistance and unneccessary adverse events. Antimicrobial stewardship programs (ASP) are effective in reducing antimicrobial use in inpatient setting. But Emergency Department (ED) is unique environment lends itself to challenges for succesful antimicrobial stewardship for outpatients. So, We want to evaluate the impact of our ASP.

Materials/methods: We performed a monocentric retrospective comparative study of all antibiotic prescriptions of patients who have been admitted to the adult ED without being hospitalized (or hospitalized les than 24H) before (Nov 2012-Nov 2013)/ after (june 2015-june 2016). Patients' files were rewied by 2 independant evaluators: an infectious disease specialist (IDS) and an ED physician. They assessed compliance of antibiotic prescriptions with national and international guidelines. Our ASP was driven by an IDS and ED physician, it included:

1) Educational course outlining ASP principles was given to ED residents every 6 months.

2) The on-call IDS was made available during regular work hours for ED consultations. ED physicians were encouraged to call him/her when uncertain about antimicrobial prescriptions.

3) One ED team member was identified as referent for antimicrobial usage and was present at everyday staff meetings. He/She raised awareness about optimized antimicrobial utilization during work hours

4) The ED physician and IDS porvided guidelines on the main infectious diseases encountered in ED. Theses guidelines were given to each resident and ED physicians as a pocket handbook


We compared the relevance and volume of antibiotics prescribed in both periods to assess the impact of our ASP.

Results:Before and after ASP, we recorded respectively 34671 vs 35925 consultations at ED, 25470 vs 26208 were outpatients. The number of antibiotics prescribed for them decreased significantly, 760 vs 580 (p<0.0001). Among these prescriptions, there was a significant decrease in non-compliant prescriptions 455 (59.9%) vs 255 (44%) (p<0.0001) of which:

- 197 (40.7%) vs 101 ( 17.4%) (p<0.001) had an unnecessary antimicrobial prescription

- 95 (19.6%) vs 54 (9.3%) (p< 0.05) had a prescription with too broad spectrum

- 87 (17.9%) vs 53 ( 9.1%) (p<0.05) had a prescription with an excessive treatment duartion.

Conclusions: Antibiotic prescriptions to outpatients in the ED are often inadequate. Thanks to ASP, antimicrobial use could be widely imrpoved, especially concerning the volume of prescribed antibiotics and prescriptions generationg the most resistances.


Julie GRENET (PARIS), Julie ATTAL, Alain BEAUCHET, Jérôme SALOMON, Clara DURAN, Sébastien BEAUNE, Aurélien DINH
15:55 - 16:00 #11628 - Trends in diagnostic patterns and mortality in emergency ambulance service patients in 2007-2014 - a population based cohort study from the north denmark region.
Trends in diagnostic patterns and mortality in emergency ambulance service patients in 2007-2014 - a population based cohort study from the north denmark region.

Objective: Demand for ambulances is growing. Nevertheless, knowledge is limited regarding diagnoses and outcome in patients receiving emergency ambulances. This study aims to examine time trends in demographic characteristics, diagnoses and mortality among patients receiving emergency ambulances.

Design: Population-based cohort study with linkage of Danish national registries.

Setting: The North Denmark Region in 2007-2014.

Participants: Cohort of 148 757 patients transported to hospital by ambulance after calling emergency services.

Main outcome measures: The incidence of emergency ambulance service patients, distribution of their age, sex, hospital diagnoses, comorbidity, and 1- and 30-day mortality were assessed by calendar year. Poisson regression with robust variance estimation was used to estimate relative risk and age- and sex-adjusted prevalence ratios for Charlson Comorbidity Index (CCI) to allow comparison of mortality rates by year, with 2007 as reference year.

Results: The annual incidence of emergency ambulance service patients increased from 24.3 in 2007 to 40.2 in 2014 per 1 000 inhabitants. The proportions of women increased from 43.1% to 46.4% and of patients aged 60+ years from 39.9% to 48.6%, respectively. The proportion of non-specific diagnoses increased during the years, whereas injuries declined. Proportion of patients with high comorbidity level (CCI>3) increased from 6.4% in 2007 to 9.4% in 2014, corresponding to an age- and sex-adjusted prevalence ratio of 1.27 (95% Confidence Interval (CI): 1.18 to 1.37). The 1- and 30-day mortality decreased from 2.40% to 1.21% and from 5.01% to 4.36%, respectively, from  2007 to 2014, which corresponds to age- and sex-adjusted relative risk of 0.72 (95% CI: 0.66 to 0.79) and 0.43 (95% CI: 0.37 to 0.50), respectively.

Conclusion: During the eight-year period, the incidence of emergency ambulance service patients, the proportion of women, elderly, and patients with non-specific diagnoses increased. The level of comorbidity increased substantially, whereas the 1- and 30-day mortality decreased.


Erika Frischknecht CHRISTENSEN, Thomas Mulvad LARSEN, Flemming Bøgh JENSEN, Hans Ole HOLDGAARD (Aalborg, Denmark), Poul Anders HANSEN, Søren Paaske JOHNSEN, Christian Fynbo CHRISTIANSEN, Mette Dahl BENDTSEN
16:00 - 16:05 #11752 - HACOR score to predict in-hospital mortality for patients with acute respiratory failure treated with non-invasive ventilation.
HACOR score to predict in-hospital mortality for patients with acute respiratory failure treated with non-invasive ventilation.

OBJECTIVES: In a group of patients with acute respiratory failure (ARF), treated with noninvasive ventilation (NIV), we tested if an early evaluation through a validated scale, using variables easily obtained at the bedside, can identify patients at high risk of adverse outcome.

METHODS: This was a retrospective study including all patients with ARF requiring NIV over a two-year period (January, 2014-July, 2016), admitted in an Emergency Department High-Dependency Observation Unit (ED-HDU). Clinical data were collected at baseline, 1 hour, and 24 hours; HACOR score (previously employed only in patients with hypoxemic respiratory failure) was calculated before NIV and after 1 and 24 hours of treatment. For prognostic analysis, the score was evaluated as continuous value and as dichotomized value (≤5 or >5, as suggested in the validation study). The primary outcome was in-hospital mortality, need of ICU admission and NIV weaning at 48 hours.

RESULTS: The study population includes 348 patients, mean age 77±15 years, 53% male gender; 249 patients presented an hypercapnic respiratory failure. Most frequent admission diagnosis were pneumonia in 59% of patients, congestive heart failure in 34% and sepsis in 20%, which overlapped in some patients.  In-hospital mortality was 22%; 86 (25%) patients needed ICU admission while 167 (48%) patients were weaned from NIV within 48 hours. Admission SOFA score was 4.3±2.5; after 24 hours of HDU stay it decreased to 3.7±2.2. Compared with survivors, non-survivors showed  significantly higher  HACOR score before NIV (8.1±5.2 vs 6.2±4.0, p=0.006), after 1 hour (6.7±5.3 vs 3.8±3.3, p<0.001) and 24 hours (4.7±4.7 vs 2.0±2.2, p<0.001) NIV treatment; moreover, HACOR score reduction during the first hour of NIV treatment was significantly higher in survivors compared with non survivors (-2.5±3.5 vs -1.4±3.5, p=0.021). Analysis for repeated measures showed a score reduction significantly more marked in survivors compared with non-survivors (p<0.001). Compared with patients with HACOR ≤5, patients with HACOR score >5 showed a significantly higher mortality rate at every evaluation point (before NIV: 27 vs 16%, p=0.019; 1-hour: 36 vs 17%, p<0.001; 24-hour: 44 vs 17%, p=0.001).  When we took into account the end-point ICU admission and early weaning (<48H), only HACOR score after 24 hours was significantly higher in patients who were admitted to ICU (3.3±2.8 vs 2.3±3.1, p=0.021) or who needed a prolonged ventilation (3.0 ±2.1 vs 2.1±3.0, p=0.011).

CONCLUSIONS: HACOR score incorporates several variables easily obtainable at the bedside; in a population of unselected patients with acute hypoxic or hypercapnic respiratory failure, treated with non-invasive ventilation, from the beginning of treatment in-hospital non survivors showed significantly higher score values compared with survivors.    


Laura GIORDANO, Simona GUALTIERI (Florence, Italy), Arianna GANDINI, Lucia TAURINO, Monica NESA, Chiara GIGLI, Alessandro COPPA, Francesca INNOCENTI, Riccardo PINI
E-Poster Area

"Monday 25 September"

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PH3 - S2
15:45 - 16:05

E-Poster Highlight Session 3 - Screen 2

15:45 - 15:50 #11330 - Value of intensive care unit prognostic scores for predicting mortality after traumatic brain injury.
Value of intensive care unit prognostic scores for predicting mortality after traumatic brain injury.

Background:

Traumatic brain injury (TBI) is a major cause of morbidity and mortality. Hence severity scales are important adjuncts to trauma care to predict the prognosis in order to improve triage decisions and identify patients with unexpected outcomes. Traumatology scores have been investigated and found to be useful in major trauma patients. However, few studies have examined the contribution of  these scores and Prognostic scores in intensive care ICU severity scales as prognostic indicators in severe TBI.

Methods:

Retrospective study of patients 18 years and older, presenting in the emergency department with isolated severe TBI and requiring mechanical ventilation between January 2015 and January 2017. Collected variables included comorbidity data, Glasgow Coma Scale (GCS), vital parameters, imaging data, popular traumatology scores (GAP, MGAP, ISS and TRISS) and common ICU scores ( APACHE II and IGS II) at admission. Fischer exact test and T-test were used when appropriate to compare mortality groups.

Results:

Twenty-nine patients were eligible for the study. Males were represented more than femals (sex ratio = 6 ), the mean age was 42 +/- 18. The overall in-hospital mortality rate was 58%. Early mortality (<24 hours) was observed in 13.8% of cases. GCS (p=0.046; 5 Vs 7.5), APACHE II score (p=0.018; 16.56 Vs 11.52) and IGS II score (p= 0.006; 44.3 Vs 31.5) were significantly associated with overall mortality whereas TRISS, GAP and MGAP as well as age, Shock Index and the presence of brain edema at admission did not prove to be significant prognostic indicators. Elderly age (p=0.04, 60 vs 40), high glycemic level at admission ( p=0.025; 2.1 vs 1.5 g/L) , APACHE II score (p=0.018; 16.56 Vs 11.52) and IGS II score (p= 0.006; 44.3 Vs 31.5) were significantly associated with mortality occurring within the first 24 hours following admission. None of the above scores was associated with late mortality.

Conclusion:

Unlike the commonly used traumatology scores like GAP, MGAP and TRISS which did not prove to be significant prognostic factors in TBI, APACHE II and IGS II are significantly associated with early and overall in-hospital mortality. Their use in traumatology for prognostication should be investigated more thoroughly in future studies.


Fatma HEBAIEB (Ariana, Tunisia), Ameni SGHAIER, Salah SNOUDA, Moez KADDOUR, Raja FADHEL, Eya HNIA, Nourreddine DEBBECH, Hassen BEN GHEZELA
15:50 - 15:55 #11342 - Predictor factors of short- term mortality in traumatic brain injury.
Predictor factors of short- term mortality in traumatic brain injury.

Background:

Traumatic brain injury (TBI) is one of the leading causes of death in traumatology. It is a very common pathology with a high mortality rate that usually affects young healthy individuals. Identifying patients who may progress to a poor clinical short-term outcome will encourage earlier therapeutic interventions in the emergency department.

Methods:

Retrospective study over 2-year period that included all patients aged 18 or more, presenting with isolated severe TBI and requiring mechanical ventilation. Demographics and comorbidity data, Glasgow Coma Scale, vital parameters, glycemia at admission and imaging data were collected. , popular traumatology scores (GAP, MGAP, ISS and TRISS) and common ICU scores ( APACHE II and IGS II) at admission were calculated. Fischer exact test and T-test were used when appropriate to compare short-term mortality group.

Results:

Twenty-nine patients were eligible for the study.  Mean age was 42 +/- 18 [16 – 82] and the sex ratio was 6. Two patients (6%) had diebetes history. %. Short-term mortality (<24 hours) was observed in 13.8% of cases. Advanced age (p=0.04, 60 vs 40), high glycemic level at admission ( p=0.025; 2.1 vs 1.5 g/L) , APACHE II score (p=0.018; 16.56 Vs 11.52) and IGS II score (p= 0.006; 44.3 Vs 31.5) were significantly associated with mortality occurring within the first 24 hours following admission. GCS of 3 at presentation, presence of bilateral fixed or dilated pupils, stress-induced hyperglycemia (non diabetic hyperglycemia) and presence of mass effect or early brain edema on initial computed tomography, traditionally associated with worse TBI outcomes were not significantly associated with short-term mortality in our study. Popular traumatology scores such as TRISS, GAP and MGAP as well as Shock Index did not prove to be significant prognostic indicators in severe TBI .

Conclusion:

Hyperglycemia, advanced age and high levels of APACHE II and IGS II scores are indicator of poor early outcome in severe and isolated TBI in the emergency department. 


Fatma HEBAIEB (Ariana, Tunisia), Ameni SGHAIER, Salah SNOUDA, Moez KADDOUR, Nourreddine DEBBECH, Abir TAKROUNI, Raja FADHEL, Eya HNIA, Hassen BEN GHEZELA
15:55 - 16:00 #11354 - Predictor factors in pneumonia-related acute respiratory distress syndrome patients.
Predictor factors in pneumonia-related acute respiratory distress syndrome patients.

BACKGROUND:Severe pneumonia remains a major cause of death. Acute respiratory distress syndrome (ARDS) and pneumonia are closely correlated in the critically ill patient and ARDS was described as an independent predictor factor of mortality in case of pneumonia. Recent research suggests that host factors have a major bearing on the development of ARDS. Other studies suggest sepsis as the principal link between pneumonia and ARDS. The aim of the study was to identify factors that predict the occurence of ARDS during severe pneumonia. 

METHODS:

Retrospective study over 2-year period that included patients 18 years and older, presenting in the emergency department with severe pneumonia diagnosis. ARDS was defined with the Berlin criteria. Fischer exact test and T-test were used when appropriate to compare ARDS group.

RESULTS: N=24.The mean age was 69 + 14 years with a sex ratio of 2. Medical history: hypertension (29,8%), diabetes (37,7%) and tobacco (60,9%). chronic respiratory failure (33,3%), chronic heart failure (12,5%), immunosuppression (32%), patients had cumulated more than three comorbidities in 46 % of cases. The mean PSI score was about 124 +39, class V: 43,5%, the CURB 65 score was greater than or equal to two in 74% of cases, the mean value of APACHE II score was 32,  IGS II score was 69  and SOFA score was 11. The only Predictive factor of ARDS was the presence of immunosuppression (p=0,01) and the APACHE II score was correlated with the risk of development of ARDS  (p=0,000; 24 vs 14). The sepsis was not a predictive factor for the occurence of ARDS during severe pneumonia in this study.   CONCLUSION: The pulmonary infection is the most frequent cause of ARDS. Immunosuppression seems be the principal predictive factor in the occurrence of ARDS in severe pneumonia patients. The APACHE II score was correlated with the risk of development of ARDS and his use in pneumonia patients for severity and prognosis assessment should be investigated more thoroughly in future studies.


Fatma HEBAIEB (Ariana, Tunisia), Eya HNIA, Salah SNOUDA, Moez KADDOUR, Raja FADHEL, Ameni SGHAIER, Abir TAKROUNI, Hassen BEN GHEZELA
16:00 - 16:05 #11814 - Incidence of cerebral edema in adult diabetic ketoacidosis patients: impact of standardisation management protocol.
Incidence of cerebral edema in adult diabetic ketoacidosis patients: impact of standardisation management protocol.

Background:

Diabetic ketoacidosis (DKA) is a frequent acute metabolic complication of diabetes mellitus. Cerebral edema (CE) is a rare therapeutic complication but it is known as the major cause of mortality and long-term morbidity in DKA patients, especially in children and young adults. Until yet, the mechanism of this severe complication remains poorly understood and guidelines for management of DKA can never be considered entirely safe.

 

Purpose:

To describe the incidence of CE after standardization of DKA therapy according to the recommendations of American Diabetes Association (ADA) published in 2009.

 

Methods:

Prospective descriptive study over 2-year period including patients aged > 16 years admitted to the emergency department for moderate to severe DKA. Standardization of DKA management occurring to ADA recommendations: fluid replacement, insulin therapy and replacement of electrolytes.

Cerebral edema was defined as deterioration in conscious level with imaging, histopathological or therapeutic confirmation (improvement after osmotherapy or assisted ventilation)

 

Results: 

We enrolled 106 consecutive DKA patients. The mean age was 36+/-16.5 years with a sex ratio of 0.63. Medical history, N (%): type 1 diabetes, 61 (57.5); type 2 diabetes, 31 (29.3); inaugural, 14 (13.2). Usual treatment, N (%): insulin, 90 (81.1); biguanides, 8 (7.5); sulfonylureas, 8 (7.5). Time to glucose control was 6.5 +/- 4 hours, time to resolution of acidosis was 13 +/- 7 hours, insulin dose to recovery was 66 Units (0.95 U/Kg). The length of stay in intensive care unit was 29 hours and mortality rate was 0.9%.Therapeutic complications were (N;%): hypoglycemia (58; 54.7), hypokalemia (21; 19.8) and Hyperchloremic acidosis (27 ; 25.7). No case of cerebral edema was documented during this study.

 

Conclusions:

Using the DKA standardized protocol improved several clinical outcomes with reducing time to resolution of acidosis and length of stay in intensive care unit and understating the incidence of fatal complications especially cerebral edema.


Fatma HEBAIEB (Ariana, Tunisia), Sarra JOUINI, Amina JEBALI, Amel MAAREF, Imen MEKKI, Alaa ZAMMITI, Aymen ZOUBLI, Chokri HAMOUDA
E-Poster Area

"Monday 25 September"

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PH3 - S4
15:45 - 16:05

E-Poster Highlight Session 3 - Screen 4

15:45 - 15:50 #11380 - Management of chronic obstructive pulmonary disease exacerbations with international guidelines.
Management of chronic obstructive pulmonary disease exacerbations with international guidelines.

Intoduction:

Chronic obstructive pulmonary disease (COPD) is the fifth cause of morbidity and mortality worldwide. Exacerbation of COPD is a sustained worsening of the patient's condition.The Global initiative for chronic Obstructive Lung Disease (GOLD) 2016 is the main recommendations document for diagnosis and management of COPD exacerbations.

The aim of our study was to evaluate the management of patients admitted to the emergency department (ED) for COPD exacerbations using international guidelines.

 

Methods:

Prospective observational study over four months period. Inclusion of adult patients admitted to the ED for COPD exacerbations. Collection of epidemiological, clinical and para-clinical characteristics. Treatment management was standardized using GOLD2016 guidelines. All the medical staff was asked to carry out the same protocol.

 

Results:

Inclusion of 198 patients. Mean age: 67±11 years. Sex ratio = 3.95. Comorbidities n(%): hypertension 39(20), diabetes 33(17), tobacco 137(69), atrial fibrillation 15(8), dyslipidemia 13(7), chronic heart failure 11(5). ABCD classification of COPD n(%): C group 19(10) and D group 112(64). COPD Assessment Test more than 10 n(%):  145(81). Symptoms n(%): cough 148(76), dyspnea 140(71), sputum production 138(72), asterixis6(3) and cyanosis10(5). Physical examination n(%): wheezing 150(75), crepitates27(13,5%) and CPC 6(3)

Short-acting inhaled beta2-agonists (SABA) were prescribed in 158 patients (80%). Nineteen patients (10%) had short-acting anticholinergics bronchodilators in addition to the SABA. All patients received systemic corticosteroids (mode of administration n(%): oral route 131(66) and intravenous 67(34)).

Non-invasive ventilation was required in 37 patients (19%). Six percents (n=12) of patients were admitted to the intensive care unit for mechanical ventilation.

Main causes of exacerbations n(%): infection 74(38), treatment cessation 46(23), acute heart failure 17(9) and pulmonary embolism 12(6).

 

CONCLUSION:

The goal of treatment in COPD exacerbations is to minimize the impact of the current exacerbation and to prevent the development of subsequent exacerbations. A protocolized protocol at the ED helps to improve management and thus to decrease complications.

 


Ines CHERMITI, Manel KALLEL (Tunis, Tunisia), Hanène GHAZALI, Soumaya MAHDHAOUI, Siwar JERBI, Sana TABIB, Najla EL HANI, Sami SOUISSI
15:50 - 15:55 #11456 - CPAP/NIPPV in patients with "e;do not intubate"e; status: preliminary data from the INVENT study.
CPAP/NIPPV in patients with "e;do not intubate"e; status: preliminary data from the INVENT study.

Background: Noninvasive ventilation (CPAP/NIPPV) is widely used to treat acute respiratory failure (ARF) in the Emergency Department (ED). Its use seems challenging also for patients who are not eligible for endotracheal intubation (ETI) both to treat ARF due to reversible causes and to relieve symptoms in end stage ARF. 

Methods: INVENT (Italian Noninvasive Ventilation in Emergency National Trial) is an observational prospective multicentric study whose aim is to outline the use of CPAP/NIPPV in Italian Emergency Departments. It involves 19 EDs and it is promoted by the SIMEU (Italian Society of Emergency Medicine) Study Center. Enrollment started in May 2015 and went on until February 2017. Data about patients treated with CPAP/NIPPV during four weeks/year, one for season, were collected.

We focused on the subgroup of patients for whom ETI was considered not indicated (Do Not Intubate: DNI) to outline the main features of DNI patients and to analyse the impact of DNI status on hospital mortality. 

Results: among 245 patients, 72 were considered DNI (29,3%). Patients with a DNI status were older (78,5±12,6 vs 73,2±13,7 years, p:0,004) and were more likely to have dementia (25,0%vs 8,2%, p<0,001) and solid tumours (31,9% vs 8,8%, p<0,001). They were less likely to have COPD (36,1% vs 56,7%, p:0,003), diabetes (18,7% vs 35,7%, p:0,012) and obesity (10,0% vs 22,9%, p:0,021). DNI patients were more likely to have ARF due to pneumonia than other causes (33,3% vs 13,5%, p<0,001).

Hospital mortality was higher in the DNI group (34,7% vs 14,6%, p<0,001). 

Among patients with a DNI status, the dead  had higher lactate levels (7,2±11,1vs 2,8±3,7, p: 0,022), lower diastolic blood pressure (DBP) levels (69,4±14,7 vs 78,8±19,2, p:0,025) and were less likely to have history of COPD than the dead. No ARF cause significantly affected hospital mortality. In the first hours of treatment, survivors showed an improvement of: DBP (77,9±19,6 to 71,1±13,0 mmHg, p:0,011), respiratory rate (RR) (29,9±6,4 to 24,7±6,7 bpm, p<0,001), pH (7,31±0,11 to 7,36±0,09, p:0,001), paCO2 (62,6±23,7 to 55,2±20,9 mmHg, p:0,001), paO2 (64,9±32,8 to 100,6±61,9 mmHg, p:0,001). 

Conclusion: DNI patients represented almost one third of those treated with CPAP/NIPPV for ARF in the ED, according to our data. They have higher hospital mortality and they are more likely to have ARF due to pneumonia. Dementia, solid tumours and an older age correlate with DNI status, while COPD patients are more likely to be not-DNI. Among DNI patients, higher lactate levels  and lower DBP levels correlate with survival rate. 

Although hospital mortality is higher in DNI patients, CPAP/NIPPV seems to be appropriate to treat ARF and to relieve symptoms of dyspnoea


Dr Stella INGRASSIA (Milano, Italy), Ombretta CUTULI, Nicola BACCIOTTINI, Giuseppina PETRELLI, Marina VOLPE, Matilde CONTI, Eliana MARGUTTI, Anna Maria BRAMBILLA
15:55 - 16:00 #11491 - Noninvasive ventilation for the treatment of acute respiratory failure in ED: preliminary data from an Italian multicentric study.
Noninvasive ventilation for the treatment of acute respiratory failure in ED: preliminary data from an Italian multicentric study.

Background: Noninvasive ventilation (NIV) is widely used to treat acute respiratory failure (ARF) in the Emergency Department (ED), in particular in acute cardiogenic pulmonary edema (ACPE) and  acute exacerbation of chronic obstructive pulmonary disease (AECOPD); its use has been described for other pathologies, such as pneumonia, pulmonary contusion or neuromuscular disorders, though evidence about these indications is still controversial.

Methods: INVENT (Italian Noninvasive Ventilation in Emergency National Trial) is an observational prospective multicentric study promoted by the Italian Society of Emergency Medicine (SIMEU) Study Center and involving 19 Italian EDs. it’s aim is to describe the reality of NIV use in Italian Eds, considering both Continuous Positive Airway Pressure (CPAP) and Non-invasive Positive Pressure Ventilation (NPPV). Patients treated with NIV were enrolled during 7 periods lasting one week from may 2015 to February 2017, 1 period for every season.

Results: We collected data from 245 patients, 138 males (56,3%), average age 74,8±0,87 years.

The indication for NIV was ACPE in 67 patients (27,3%),AECOPD in 56 (22,9%), pneumonia in 47 (19,2%), neuromuscular disorders in 6 (2,4%). 45 patients (18,3%) were treated because of a mixed indication: 13 (5,3%) had ACPE and AECOPD, 14 (5,7%) had ACPE and pneumonia and 18 (7,3%) had AECOPD and pneumonia. 47 patients (19,2%) were treated with NIV because of a mix of other pathologies. 

The initial modality of ventilation chosen was CPAP in 65% of patients with ACPE, 17,6% of patients with AECOPD, 51,9% of patients with pneumonia, and 1,67% of patients with neuromuscular disorders. The other patients were started firstly on NPPV.

The preferred interface using CPAP was the oronasal mask (66,4%), followed by the Helmet (33,9%), the full face (4,4%) and the nasal (0,9%) masks. For NIPPV the oronasal was still the most used interface (75,7%), followed by the full face mask (24,3%). In a few patients more than one device was used due to intolerance. CPAP was stopped because of intolerance in 10 patients (10,2%), while NIV in 11 patients(7,5%). Sedation was needed in 28 patients (11,4%).

19 patients (7,8%) underwent endotracheal intubation.  72 patients (29,4%) were considered not eligible for endotracheal intubation (DNI) by the treating physician.

Overall in-hospital mortality was 20,4% (50 pts), while it was 16,3% in ACPE patients (15/92), 10,6% in AECOPD patients (9/85), 31,2% in pneumonia patients (24/77) and 33,3% in neuromuscular disorder’s patient.

Conclusion: NIV is used in Italian EDs for many pathologies. CPAP is preferred in patient with ACPE, while NPPV is the ventilatory support of choice in AECOPD. The preferred interface in our study was the oronasal one. The mortality rates are consistent with the value found in literature.  These are preliminary data of an ongoing study, further investigations are needed to investigate this topic.


Dr Stella INGRASSIA (Milano, Italy), Andrea DUCA, Antonio VOZA, Luisa MAIFRENI, Paola NOTO, Alice MORELLI, Paolo GROFF, Roberto COSENTINI
16:00 - 16:05 #11507 - Intravenous Lipid Emulsion Treatment: Review of the effect on Lipophilicity.
Intravenous Lipid Emulsion Treatment: Review of the effect on Lipophilicity.

Intravenous Lipid Emulsion Treatment: Review of the effect on Lipophilicity

Background: Although the action mechanism of intravenous lipid emulsion has not been fully elucidated yet, its use in liposoluble drugs intoxications. Mechanism of effect is suggested that lipid sink theory, cardiotonic effect and positive inotropic effect by increasing the calcium level via the calcium channels. The aim of this systematic review is to investigate the relationship with the lipophilic feature (log p values) of drugs and the success rate of ILE therapy in poisoned patients.

Methods: We reviewed 765 cases published in PubMed between 1966 and June, 2015. After applying exclusion criteria, totally 141 cases ingested single substance and received ILE therapy with 20% ILE solution were included in present study. Amount of lipid solutions given and the results were recorded. Success rate was statistically assessed according to log p values of the substances taken and the amount of lipid emulsion used.

Results: 141 patients were involved in this study; log p values were calculated for all drugs regardless of the success of ILE therapy. Amount of ILE therapy given was ≤500 mL in 87 (61.7%) (≤100 mL in 14 (9.9%)) and >500 mL in 54 (38.3%) of the cases. The success rate was 85.1% in patients received ILE therapy≤500 mL, whereas the same rate was 92.6% in patients that received ILE therapy>500 mL. There was no significant difference between groups received ILE therapy≤500 mL or >500 mL (p=0.142). When amount of lipid emulsion given was below 500 mL (1-500 mL), the log p value, especially the ALOGPS and ChemAxon data, becomes more important. In cases that received ILE therapy≤500 mL, the ALOGPS and ChemAxon log p values were higher in the group with successful outcome than those observed in cases, in which ILE therapy was failed (p values are 0.043 and 0.008). In addition, Experimental log p value was higher, indicating a trend towards statistical significance (p=0.071). Thus, we can argue that log p value has significant effect on treatment success when amount of lipid emulsion is equal or below 500 mL. But, there is no significant effect of treatment outcome when amount of lipid emulsion is higher than 500 mL

ILE therapy under the amount of 100 mL failed to achieve successful outcome. ALOGPS and ChemAxon log P values were higher in cases, which received ILE therapy ≤500 mL and showed successful results. It was found that log p value had no contribution to the treatment success in the group received ILE therapy >500 mL.

Conclusions: It was found that ILE therapy500 mL, and that liposolubility had no significant contribution to treatment success. It could be thought that additional action mechanisms other than lipid sink phenomenon are more active in ILE therapy.


Evvah KARAKILIÇ (Eskisehir, Turkey), Elif CELIKEL, Ahmet Burak ERDEM, Engin Deniz ARSLAN, Tamer DURDU
E-Poster Area

"Monday 25 September"

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PH3 - S5
15:45 - 16:05

E-Poster Highlight Session 3 - Screen 5

15:45 - 15:50 #10086 - Possibility of early diagnosis and treatment of acute abdomen by using point of care creatinine device prior to abdominal contrast enhanced computed tomography in emergency department.
Possibility of early diagnosis and treatment of acute abdomen by using point of care creatinine device prior to abdominal contrast enhanced computed tomography in emergency department.

Background

The contrast enhanced computed tomography (CECT) is essential in the diagnosis of the emergent fatal abdominal disease. However, due to the fact that contrast media may cause contrast-induced nephropathy especially in patients with acute kidney injury or chronic kidney disease, CECT may be delayed until the result of serum creatinine is confirmed. Point-of-care (POC) creatinine device enables to achieve serum creatinine within 30 seconds thus we introduced this device from Jan 2015 in our emergency department and have used it routinely since then. The purpose of this study is to assess how the POC creatinine device has affected the application of CECT and prompt treatment in emergency department.

 

Material and methods

The abdominal CT taken from emergency department between Jan 2013 and Dec 2016 were retrospectively analyzed. CTs taken before Jan 2015 were grouped as “before POC”, and from Jan 2015 were grouped as “after POC”. The changes in the number of plain CT, CECT, and an additional CECT after plain CT (add-CECT) before and after POC were evaluated. The rate of the patients who required urgent surgery or endoscopic procedure in add-CECT group before and after POC was also analyzed.

 

Results

The total numbers of CT in “before POC” and “after POC” were 2046 and 2499, respectively. The rate of CECT increased significantly from 233/2046 (11.4%) to 453/2499 (18.1%) by the introduction of POC (p<0.01). The rates of add-CECT to all CECT in before and after POC were 47/233 (20.2%) and 94/453 (20.7%), respectively (n.s.). The rate of the patients who required urgent surgery or endoscopic procedure  in add-CECT before and after POC were 12/47 (25.5%) and 37/94 (39.3%), respectively (n.s.).

 

Conclusion

The rate of abdominal CECT in emergency department has increased significantly after the introduction of POC creatinine device. This may have assisted early and accurate diagnoses of fatal diseases within limited time. However, because the rate of add-CECT, and patients who required urgent surgery or endoscopic procedure after add-CECT, did not decrease, POC creatinine devices may have only lowered the threshold of the application of CECT. Thus, we must be careful in the proper use of CECT especially if it is easily applicable.


Shotaro KAWAMURA (Nagoya, Japan)
15:50 - 15:55 #10531 - Improvements of the difficulty in hospital acceptance at the scene by the introduction of smartphone application for emergency-medical-service system: A population-based before-and-after observation study in Osaka City, Japan.
Improvements of the difficulty in hospital acceptance at the scene by the introduction of smartphone application for emergency-medical-service system: A population-based before-and-after observation study in Osaka City, Japan.

Background: Recently, the number of ambulance dispatches has been increasing in Japan and it is, therefore, difficult to accept emergency patients to hospitals smoothly and appropriately because of exceeding the hospital capacity. To facilitate the request for patient transport by ambulance and hospital acceptance, the emergency information systems using information technology (IT) has been built up and introduced in various communities. However, its effectiveness has not been insufficiently revealed in Japan. Herein, we developed a smartphone application system that enable the emergency medical service (EMS) to share information about ambulance and hospital situation in 2013. The aim of this study was to assess the implementation effect of this application for EMS system in Osaka City, Japan.

Methods: This study was a retrospective study with population-based ambulance records of Osaka Municipal Fire Department. This study period was six years from January 1, 2010 to December 31, 2015. In this study, we enrolled emergency patients that on-scene EMS personnel conducted the hospital selection for them. The main endpoint was difficulty in hospital acceptance at the scene. The definition of difficulty in hospital acceptance at the scene was to make >=5 phone calls by EMS personnel at the scene to each hospital until a decision to transport was determined. The definition of using smartphone application is the period of 2013-2015 after the introduction of this application since in 2013, and we assessed the effect of using smartphone application with multivariable logistic regression model.

Results: A total of 600,526 emergency patients who EMS personnel selected hospitals were eligible for our analysis in this study. There were 300,131 cases (50.0%) without using the smartphone application in 2010-2012 and 300,395 cases (50.0%) with using the smartphone application in 2013-2015. The proportion of the difficulty in hospital acceptance without using smartphone application was 14.2% (42,585/300,131) and that with using smartphone application was 10.9% (32,819/300,395), and the difficulty in hospital acceptance significantly decreased by the introduction of the smartphone application (adjusted odds ratio; 0.730, 95% confidence interval; 0.718-0.741, P<0.001).

Conclusion; Sharing information between ambulance and hospital by using IT was associated with decreasing the difficulty in hospital acceptance. Our findings may be considerable useful for developing emergency medical information system with IT in other areas of the world.


Yusuke KATAYAMA (SUITA, Japan), Tetsuhisa KITAMURA, Kosuke KIYOHARA, Sumito HAYASHIDA, Taku IWAMI, Takashi KAWAMURA, Takeshi SHIMAZU
15:55 - 16:00 #11062 - Motivation of employees in pre-hospital and in-hospital emergency care in Bulgaria.
Motivation of employees in pre-hospital and in-hospital emergency care in Bulgaria.

Motivation of employees in pre-hospital and in-hospital emergency care in Bulgaria.

Desislava Katelieva MD, phD; Lora Georgieva MD, phD, ass.prof.

Key words: emergency care, Bulgaria, motivation

Background: The shortage of personnel in emergency care in Bulgaria is a serious problem. Regardless of subsequent wage increases in recent years, the system has a fluctuation and insufficient number of specialists.

Methods: A research was conducted by semi-structured questionnaire in 2016 to identify attitudes, reasons for leaving or staying in the system. The data was processed by descriptive statistics, nonparametric chi-square test, correlation analysis (Spearman's coefficient) and regression analysis (linear regression). The study involved 291 participants: 149 (51,2%)  of outpatient care centers and 142 (48,8%) from emergency departments. The average age of respondents was 47,7 +/-9,2 years. According to their qualification the participants were: 97 physicians (33,3 %); 76 feldshers (26,1%); 93 nurses (32,0%) and 25 drivers (8.6%).

Results: 210 of the respondents (72,2%) do not intend to leave – 66,7% of whom like their job, and 5,5% cannot find professional realization elsewhere. Respondents who intend to leave state as reasons: their intention to work outside of medicine (6,6%); to work abroad (9,6%); to work in another medical facility (8,95%). The leading motive for staying in systems is the satisfaction of saving a human life for 190 (65,3%) of those surveyed, followed by free time between shifts-178 (61,2%) and reduced working time - 114 (39,2%). According to 232 (79,7%) salary is not a motivating factor to work in the system of emergency aid. According to 244 (83,3%) of respondents career development opportunities are not satisfactory. A statistically significant difference between satisfaction with career development and qualification of the respondents (chi2 = 2,410, p = 0,566) is not established. As possible incentives to remain in the system of emergency aid respondents indicate: measures to restrict aggression (67,4%); the introduction of clear rules (60,1%); more opportunities for further training (59,1%); the introduction of triage (51,5%).

In recent years, emergency teams are increasingly subjected to physical and verbal aggression. Among the respondents, 81,1% were subject to physical aggression, while 93,5% - to verbal aggression. Mostly physicians are victims of physical aggression (r = 0,153, p = 0,009). A causal link between the frequency of unfounded calls and surveys and frequency of physical aggression (B =-0,349, p = 0,001) is found through linear regression.

Discussion: In order to solve the problem with staff fluctuation and shortage of specialists in emergency assistance, it is essential to seek the reasons behind their departure. The motivation factors include: decent pay, good working conditions, measures against the physical and verbal aggression, and opportunities for career development.

 


Desislava KATELIEVA (SOFIA, Bulgaria), Lora GEORGIEVA
16:00 - 16:05 #11064 - Application of telemedicine in prehospital emergency care in Bulgaria.
Application of telemedicine in prehospital emergency care in Bulgaria.

Application of telemedicine in prehospital emergency care in Bulgaria

Desislava Katelieva MD, phD; Atanas Mitkov MD; Dimitar Shandurkov MD

Keywords: telemedicine, telemedicine consultation, Center for outpatient emergency care

Background: The lack of nearby hospitals and doctors in Bulgaria, requires the introduction of telemedicine in emergency care. In January 2014 a pilot project was launched to introduce a multifunctional system monitoring, defibrillation and telemedicine in remote, hard-to-reach regions, operated by emergency crews without a doctor. This device has an integrated defibrillator and monitor of the vital indicators (the blood pressure, pulse, O2, CO2, body temperature), transmitted in real time over the Internet to the Center for telemedicine consultation. The pilot project starts with a peripheral device, used to train teams in Krumovgrad. The consultations are carried out by physicians in the coordination headquarters of outpatient emergency aid. The Ministry of health has purchased the first two peripheral devices for out-patient centers of emergency in Krumovgrad and Ardino in February 2015

Metods: Analysis of telemedicine consultations was carried out in Krumovgrad according to age, gender, the need to set hospitalization and diagnoses of patients for the period 22.02.2015. - 22.02.2017. The center for outpatient emergency aid in Krumovgrad covers 19907 people on a territory of 843 km2. and is situated 47 km. from the regional hospital.

Results: A total of 135 telemedicine consultations for patients (65% are male and 45% female) were conducted for the research period. According to their age patients are: children-1 (0,2%); young people up to 30 years - 3 (2,2%); people with an average age of 30-60 years- 43 (32%) and over 60 years- 88 (66%). The diagnoses set after consultations, are mainly cardiac – ACS 27 (17%); pulmonary tromboembolism 7 (5%); rhythm-conduction disorders 26 (19%); arterial hypertension 34 (25%); respiratory failure 19 (14%) and clinically healthy 22 (16%). After consultation with physicians the emergency teams hospitalized 34 patients (25%). Telemedicine consultations during the first year were only 36, and in the second year they have increased 2,7 times. The relative amount of hospitalizations during the first year was 28%, in the second year decreasing to 24% due to increasing telemedicine consultations.

Discussion: After positive experiences from Krumovgrad, in September 2015 the State equipped more than 18 outpatient center with 22 new peripheral devices for telemedicine. Unfortunately a single center for telemedicine is still missing. The increase in emergency teams without doctor requires the application of medical control over their activities. A good and secure communication between emergency teams and doctors in hospitals is needed. Telemedicine guarantees patients, served by a team without a doctor, with competent and timely physician advice and reduces hospitalizations.


Desislava KATELIEVA (SOFIA, Bulgaria), Dimitar SHANDURKOV, Atanas MITKOV
E-Poster Area
16:10

"Monday 25 September"

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A24
16:10 - 17:40

Analgesia and Sedation (Cutting Edge)

Moderators: Pr Jim DUCHARME (Immediate Past President) (Mississauga, Canada), Christian HOHENSTEIN (PHYSICIAN) (BAD BERKA, Germany)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
16:10 - 16:40 Pain treatment in the addict. Pr Jim DUCHARME (Immediate Past President) (Speaker, Mississauga, Canada)
16:40 - 17:10 Ketadex, Ketofol or Dexofol – foolish sedation procedures? Christian HOHENSTEIN (PHYSICIAN) (Speaker, BAD BERKA, Germany)
17:10 - 17:40 Sedating small adults - ketamine as the safe option? Santiago MINTEGI (Section Head. Pediatric Emergency Department) (Speaker, Bilbao, Spain)
Trianti Hall

"Monday 25 September"

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16:10 - 17:40

Geriatric (How to)
Quiz Session!

Moderators: Jacinta A. LUCKE (Emergency Phycisian) (Haarlem, The Netherlands), Pr Christian NICKEL (Vice Chair ED Basel) (Basel, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
16:10 - 16:25 Diagnosis and management of UTI in older patients. Roberta PETRINO (Head of department) (Speaker, Italie, Italy)
16:25 - 16:40 Sepsis in older patients. Pr Abdelouahab BELLOU (Director of Institute) (Speaker, Guangzhou, China)
16:40 - 16:55 Silver trauma, pre-hospital and in-hospital. James WALLACE (Consultant in Emergency Medicine) (Speaker, Warrington, United Kingdom)
16:55 - 17:10 Polypharmacy/De-prescribing. Jacinta A. LUCKE (Emergency Phycisian) (Speaker, Haarlem, The Netherlands)
17:10 - 17:25 How to apply scientific evidence to older patients. Simon. P. MOOIJAART (Internist-geriatrician) (Speaker, LEIDEN, The Netherlands)
17:25 - 17:40 The unstable older patient. Mehmet Akif KARAMERCAN (Chair of EuSEM Research Committee) (Speaker, ANKARA, Turkey)
Mitropoulos

"Monday 25 September"

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16:10 - 17:40

Resuscitation (Game Changers)

Moderators: Wilhelm BEHRINGER (Chair) (Vienna, Austria), Alice HUTIN (PH) (Paris, France)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
16:10 - 16:40 Emergency Preservation and Resuscitation - not CPR: delayed resuscitation from traumatic death. Samuel TISHERMAN (Speaker, Baltimore, USA)
16:40 - 17:10 Emergency Cardio-Pulmonary Bypass (ECPB) in the prehospital setting. Alice HUTIN (PH) (Speaker, Paris, France)
17:10 - 17:40 Refractory cardiac arrest: Ethical dilemma? Tobias CRONBERG (Speaker, Sweden)
Banqueting Hall

"Monday 25 September"

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D24
16:10 - 17:40

YEMD - Prehospital

Moderators: Gerhard ADAMEK (Praticien Hospitalier (M.D.)) (SAINT-RENAN, France), Mohomed ASHRAF (Registrar) (UK, United Kingdom)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
16:10 - 16:30 Controversy in Airway management. Sanela RADOSAVLJEVIC (emergency phisician) (Speaker, Belgrade, Serbia)
16:30 - 16:50 Debating between scoop and run versus stay and play in the pre-hospital setting. Gerhard ADAMEK (Praticien Hospitalier (M.D.)) (Speaker, SAINT-RENAN, France)
16:50 - 17:10 Major incident/Disaster planning: how to manage resources and skills as a young doctor better. Michael SPITERI (Speaker, Mosta, Malta)
17:10 - 17:30 Being a HEMS doctor & how it has influenced my practice in the ED. Leonieke VLAANDEREN (HEMS registrar) (Speaker, London, United Kingdom)
Skalkotas

"Monday 25 September"

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16:10 - 17:40

Paediatric
Ultrasound scenarios

Moderators: Silvia BRESSAN (Moderator) (Padova, Italy), Pr Luigi TITOMANLIO (Head of Department) (Paris, France)
Coordinator: Niccolò PARRI (Coordinator, Florence, Italy)
16:10 - 16:55 Ultrasound scenario. Ron BERANT (Department Director) (Speaker, Petah Tikva, Israel)
16:55 - 17:40 Ultrasound scenario. Niccolò PARRI (Attending Physician) (Speaker, Florence, Italy)
MC-3

"Monday 25 September"

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F24
16:10 - 17:40

Free Papers Session 7

Moderators: Agnès RICARD-HIBON (Medical Chief) (Pontoise, France), Dr Anastasia SFAKIOTAKI (Emergency Physician) (Melbourne, Australia)
16:10 - 16:20 #11005 - OP055 Abdominal sonographic evaluation as a screening test to reduce the CT scans in trauma patients.
OP055 Abdominal sonographic evaluation as a screening test to reduce the CT scans in trauma patients.

Computed tomography is the golden standard for evaluating haemodynamically stable blunt trauma patients. As a consequence, medical radiation induced cancers have been increasing exponentially. Ultrasound evaluation has been actively investigated as an alternative, but currently an ultrasound based algorithm for the investigation of blunt trauma patients cannot be supported. In this study instead of correlating ultrasound imaging findings to computed tomography imaging findings we correlate ultrasound imaging findings with patient clinical outcomes. This prospective clinical study took place in Nikaia general hospital Greece, between 6/2014 and 12/2014. We studied 60 (sixty) consecutive, haemodynamically stable, adult, blunt trauma patients, without injuries requiring immediate surgical intervention or hospitalisation, who met abdominal CT investigation criteria. All patients were initially investigated and treated according to current ATLS recommendations. An abdominal ultrasound evaluation was performed in all patients prior to the CT scanning. The ultrasound examination was performed by an ultrasound expert radiologist. We assessed the presence of free fluid as well as all solid abdominal organs for evidence of injury. Patients then underwent a formal trauma protocol abdominal CT. All patients were admitted to the surgical ward for a minimum of 48-hour observation, where they were closely monitored and investigated.  If there was no deterioration patients were discharged. In any other case patients were treated accordingly. In 21/60 patients, the ultrasound was negative for fluid and solid organ injury. A further 21/60 despite the presence of free fluid no solid organ injury was detected. Of these patients 7/42 were found to have some degree of solid organ injury at CT.  All 42 patients (100%) had an uneventful clinical course and were safely discharged. In 12/60 patients, ultrasound was positive for fluid and solid organ injury, all 12 patients had some degree of solid organ injury in the subsequent CT scan. Of these patients 25% were eventually treated surgically. In 6/60 patients, ultrasound was negative for free fluid but positive for solid organ injury. 5/6 of these patients had some degree of solid organ injury on CT. From this patient group 1/6 needed surgical intervention. This study provides evidence that abdominal ultrasonographic evaluation of trauma patients, when performed by an experienced professional can safely be used as a screening tool, since negative ultrasound findings correlate with 100% non-surgical clinical outcome and positive ultrasound findings correlate with a 100% positive CT findings and a 25% need for surgical intervention. Taking these results a step forward, it could be implied that blunt trauma patients can be safely discharged and followed up based on an ultrasound based algorithm.


Dimitrios TSIFTSIS, Panagiotis KAZAKIDIS, Anthimos CHATZIVASILIOU, Vasilios STOUKAS (Athens, Greece), Pavlos IOANNIDIS
16:20 - 16:30 #11300 - OP056 Discordance between Emergency Physicians (EP) and Radiologists (RA) interpretation of chest X ray: prospective observational study on 402 patients.
OP056 Discordance between Emergency Physicians (EP) and Radiologists (RA) interpretation of chest X ray: prospective observational study on 402 patients.

Introduction

Chest X ray (CXR) is the most frequent imaging exam in the Emergency Department (ED). However, its interpretation is frequently difficult; thus, CXR based clinical decisions might be harmful. We investigate discordance (DI) between EP and RA on CXR interpretation prescribed for a non-traumatic indication.

Patients and methods

inclusion criteria

patients older than 15 years old

non traumatic indication

exclusion

pregnancy,

method

This observational study was conducted in the ED of a teaching hospital with an annual census of 75000 patients. During a 3-month period, EP and ED residents completed a reporting form for a convenience sample of patients with CXR. It included clinical features, a CXR systematic analysis and a conclusion. A similar form without clinical features was completed by RA being blind to the EP interpretation.

The main objective was DI between EP and RA. Secondary objectives were performance of EP interpretation, therapeutic and orientation impact induced by all CXR, therapeutic errors induced by a wrong interpretation and potentially serious illnesses missed by EP. RA interpretation was considered as the gold standard.

Statistics

For a DI 0.1, with alpha risk 0.05 and beta 0.1, the required number of patients was 196. Qualitative data were expressed as percentage and 95% confidence intervals. They were compared by a Chi2 test, p < 0.05 being significant.

Results

417 patients were included, 15 were excluded for lack of clinical informations. Age was 61 + 15 years old, sex ratio 1.09. CXR quality was assessed as good for 266 for EP and 136 for RA (p < 0.0001). DI was 23% [19-27%]. Sensitivity, specificity, negative predictive value, positive predictive value were 87% [82-86%], 64% [54-71%], 80% [72-85%] and 75% [69-80%] respectively. Therapeutic and orientation impacts of all CXR were 44% [39-49%] and 19% [15-23%], respectively. Due to wrong EP interpretation, 42 antibiotics and 31 diuretics were mistakenly prescribed. Eight suspect opacities were missed.

Discussion

DI in our ED was comparable to other published studies. The main limit was a selection bias since only 20% of all prescribed CXR during the study period were included. Despite a rather bad quality and a DI affecting 23% of CXR, therapeutic impact of CXR remains high. Training of EP and ED residents to CXR interpretation has to be organized. However, intrinsic diagnosis qualities of this exam remain poor even with good realization and interpretation.

Implementation of lung Point-of-Care Ultrasound which has demonstrated far better performance might be interesting. This diagnosis procedure is inexpensive, radiation free, performed on the patient’s bedside and with immediate result.


Sarah-Lou GUYOT, Amal KENZI, Olivier MORLA, Eric BATARD, Philippe LE CONTE (Nantes)
16:30 - 16:40 #11565 - OP057 Assessment of left ventricular ejection fraction by the emergency physician versus the cardiologist: A concordance study about 52 cases.
OP057 Assessment of left ventricular ejection fraction by the emergency physician versus the cardiologist: A concordance study about 52 cases.

Introduction

Transthoracic echocardiographic examination (TTE) that is performed at the patient’s bedside in emergency departments has several recognized important indications.

 

Objective

 The purpose of our study is to evaluate the agreement of the estimates of left ventricular ejection fraction (LVEF) obtained by emergency physicians with the findings obtained by cardiologists in patients admitted to emergency departments.

 

Material and methods

This randomized prospective study was carried out in the emergency department of the military hospital of Tunis (Tunisia) over a period of 6 months going from September 2015 through February 2016, and involving patients aged > 16 years whose condition required an emergency TTE.

The patients included in the study had to undergo a double echocardiographic examination:

1-An initial investigation that was performed in the emergency department by an emergency physician who had previously received a three-month training in Doppler echocardiography.

2-A subsequent echocardiographic examination that was performed by an echo-Doppler proficient cardiologist.

Left ventricular ejection fraction was evaluated by both readers using the following methods:

1-the global visual estimation (GVE) method,

 2-Teicholtz’s method in time movement mode (TM)

3-and Simpson Biplan method (SB).

We excluded from the study patients with:

1-segmental kinetic disorders

2-or with hearts out of alignment.

The findings thus obtained were compared using the inter-class concordance coefficient of Cronbach’s alpha.

 

Results 

Fifty-two patients were involved in the study. Mean age was 55 + 11 years; sex-ratio was 7 males/4 females.

-For the GVE method, the findings obtained by the emergency physician were similar to those obtained by the cardiologist: alpha = 0.72 (IC 95% = [0.68-0.78]; p<10-3).

-The findings obtained by both operators by Teicholtz’s method were as follows: alpha = 0.94 (IC 95% = [0.80-0.95]; p<10-3).

-The concordance of the findings obtained by the emergency physician and of those obtained by the cardiologist for their assessment of LVEF by SB method was shown by alpha=0.91 (IC95% = [0.80 – 0.98]; p<10-3).

 

Conclusion

Global visual estimation of LVEF can be performed similarly by an emergency physician or by a cardiologist provided they are sufficiently experienced. The results yielded by both other methods (Teicholtz’s method and SB method) were very similar indicating an excellent concordance independently of the degree of deterioration of the left ventricle contractility. Biplan Simpson’s method is, however, a time-consuming procedure.


Bassem CHATBRI (Tunis, Tunisia), Mehdi BEN LASSOUED, Ala ZAMMITI, Mounir HAGUI, Yousra GUETARI, Rim HAMMAMI, Maher ARAFA, Ghofrane BEN JRAD, Ines GUERBOUJ, Olfa DJEBBI, Khaled LAMINE
16:40 - 16:50 #11825 - OP058 A systematic Review and Meta-analysis of the Management and Outcomes of Isolated Skull Fractures in Children.
OP058 A systematic Review and Meta-analysis of the Management and Outcomes of Isolated Skull Fractures in Children.

Objective: Most studies of children with isolated skull fractures have been relatively small, and rare adverse outcomes may have been missed. Our aim was to evaluate the short-term clinical outcomes of children with isolated skull fractures.

Methods: We performed a systematic review and meta-analysis of studies indexed in EMBASE, MEDLINE and Cochrane Library databases through August 2016 reporting on short-term outcomes of children ≤18 years with linear, non-displaced, isolated skull fractures (i.e. without intracranial injury on neuroimaging). Two reviewers independently reviewed identified articles for inclusion, assessed quality and extracted relevant data. Our primary outcome was emergent neurosurgery or death. Secondary outcomes were hospitalization and new intracranial hemorrhage on repeat neuroimaging.  We calculated a pooled estimate of each outcome by fitting a random-effects model and then tested for heterogeneity across studies.

Results: Of the 385 studies screened, the 21 that met our inclusion criteria, included 6646 children with isolated skull fractures. One child needed emergent neurosurgery and no children died [pooled estimate: 0.0%, 95% confidence interval [0.0-0.0%]; I2 =0%]. Of the 6280 children with known emergency department disposition, 4914 (87%, 95% CI 78-95%; I2 = 98%) were hospitalized.  Of the 644[SB1]  children that underwent repeat neuroimaging, six had a non-operative intracranial hemorrhage (0.0%, 95% CI 0.0-0.1%; I2 = 79%).

Conclusion:Children with isolated skull fractures were at extremely low risk for emergent neurosurgery or death, but were frequently hospitalized. After careful consideration of non-accidental trauma, clinically stable children with an isolated skull fracture could safely be managed outpatient.


Silvia BRESSAN (Padova, Italy), Luca MARCHETTO, Todd LYONS, Michael MONUTEAUX, Liviana DA DALT, Lise NIGROVIC
16:50 - 17:00 #11888 - OP059 THE IMPACT OF CLINICAL PATHWAYS ON ANTIBIOTIC PRESCRIBING IN THE EMERGENCY DEPARTMENT.
OP059 THE IMPACT OF CLINICAL PATHWAYS ON ANTIBIOTIC PRESCRIBING IN THE EMERGENCY DEPARTMENT.

Background and Objectives

Italian pediatric antimicrobial prescription rates are among the highest in Europe. To date it has not been paid adequate attention on how to implement and improve the antimicrobial prescriptions. As a first step for antimicrobial stewardship (AS) implementation, clinical pathways (CP) outlining standard of care for acute otitis media (AOM), and group A streptococcus (GAS) pharyngitis were developed and implemented on 1 October 2015 at the Pediatric Emergency Department in collaboration with Children’s Hospital of Philadelphia.

The primary aim of this study was to assess changes in antibiotic prescription before and after CP implementation for AOM e GAS pharyngitis; secondary aims were to compare treatment failure and to assess the change in the total antibiotics costs before and after CP implementation.

Methods

Pre-post quasi-experimental study comparing the 6-month period prior to CP implementation (baseline period: 15/10/2014-15/04/2015) and during the 6 months after intervention (post intervention: 15/10/2015-15/04/2016).

We assessed differences in various measures of antibiotic prescription appropriateness, including type and breadth of spectrum prescribed, using chi-square and t-tests as appropriate. We also assessed the total cost and the cost for each class of antibiotics comparing the two groups and relating it to 1000PD.

Results

295 pre- and 278 post-intervention clinic visits were associated with AOM. After CP implementation there was an increase in “wait and see” (21.7%vs.33.1%,p<0.01) and a decrease from 53.2% to 32.4% (p<0.01) in overall prescription of broad-spectrum (BS) antibiotics. The total cost was significantly reduced (8.033,08€/1000PDvs. 5.878,30€/1000PD), with a decrease especially in BS antibiotics, above all cephalosporines, and a slight increase in the cost for amoxicillina. 151 pre- and 166 post-implementation clinic visits were associated with GAS pharyngitis, with decrease in BS prescriptions (46.4%vs.6.6%,p<0.01). The total cost was reduced (9.337,68€/1000PDvs. 6.247,23€/1000PD), with a sharp decline in the cost for BS antibiotics and an increase in the cost for narrow spectrum antibiotic contextually to the increase in its use.

Discussion

Our study showed sustained changes in physicians' prescribing behaviors for AOM and GAS pharyngitis after implementation of a clinical pathway. Prescribing changes for AOM included an immediate increase in “observation with close follow-up” approach and amoxicillin prescriptions with a concomitant decrease in BS antibiotic prescriptions. Complying with the CP, a dramatic increase of amoxicillin prescriptions for GAS pharyngitis was documented with a concomitant decrease in BS antibiotic use. In summary, our data show that clinical pathways for AOM and GAS pharyngitis are associated with reduced rates of antimicrobial prescription and cost for antibiotics purchase with no significant change in treatment failure rates.


Daniele DONA' (Padua, Italy), Maura BARALDI, Giulia BRIGADOI, Rebecca LUNDIN, Marco DAVERIO, Silvia BRESSAN, Rana HAMDY, Theoklis ZAOUTIS, Liviana DA DALT, Carlo GIAQUINTO
17:00 - 17:10 #10738 - OP060 An insight into the patient’s perspective of trauma care using point of view glasses.
OP060 An insight into the patient’s perspective of trauma care using point of view glasses.

Background:

Trauma patients are particularly vulnerable to negative experiences of healthcare. The psychological effects of trauma and restricted movement from cervical spine immobilisation combine to heighten a patient’s fear and anxiety. One factor identified to reduce anxiety amongst spinal immobilised patients is eye contact, however this has been neglected from communication tools used within emergency medicine. One explanation for this is the relative challenge of objectively assessing eye contact between doctor and patient using traditional methods.

New wearable technologies offer a way of addressing this blind spot in assessing doctor-patient communication. We subsequently set out to examine the use of point of view glasses as a method of objectively assessing the frequency and location of eye contact between a spinal immobilised patient and doctors in high fidelity trauma simulation.

 

Methods:

This study was integrated into an emergency medicine module for clinical medical students. High fidelity trauma simulations requiring cervical spinal immobilisation were recorded using covert point of view glasses and ceiling mounted cameras. The simulation footage was analysed, examining the frequency of paired verbal communication and eye contact at five predefined locations around the patient (the foot of the bed, bellow the waist, above the waist, above the shoulders and at the head of the bed).

Results:

110 communication events and 29 eye contact events were observed during six high fidelity simulations. There was a significant difference in the number verbal communication events and eye contact events below the waist, above the waist and above the shoulders (p=0.0312, 0.0156 and 0.0312 respectively). Verbal communication at the head of the bed achieved the greatest eye contact on 95% of occasions (p=0.500).

 

Conclusion:

Whilst methods for assessing communication skills have been validated for emergency medicine, they have neglected non-verbal communication that can only be assessed from the patient’s perspective.

Using new point of view technologies this study demonstrates an objective method for the identification of non-verbal doctor-patient communication and highlights the poor attainment of eye contact amongst medical students when managing trauma patients. Although this cannot be extrapolated to clinician’s, greater awareness of body position when communicating with spinal immobilised patients, especially in the absence of an anaesthetist, will help to improve eye contact with patients.

Whilst the priority for trauma patients will always be managing their medical condition it is important to give consideration to the patient’s experience, especially for vulnerable groups such as trauma patients. With this awareness and incorporation into current communication tools we aim to provide further feedback for learners during simulation, improving communication and thereby the patient’s experience of trauma care.

 


Samuel MAESE (London, United Kingdom), Andrew ARMSON, Anna WOODMAN
17:10 - 17:20 #11526 - OP061 Predictive factors for the failure of high flow nasal cannula therapy in children with bronchiolitis in pediatric emergency department.
OP061 Predictive factors for the failure of high flow nasal cannula therapy in children with bronchiolitis in pediatric emergency department.

Background: Bronchiolitis is a lower respiratory tract infection affecting principally the small airways. The disease is the most common cause of infant hospitalization during the winter months. High flow nasal cannula therapy is recommended in patients with severe disease. The aim of the study was to determine the parameters associated with high flow nasal cannula therapy failure in children with bronchiolitis in pediatric emergency department.

Methods: The patients were aged between 6 weeks and 24 months presenting to the pediatric emergency department of the Health Sciences University, Tepecik Teaching and Research Hospital with acute bronchiolitis between 01.01.2014 and 31.12.2015 were evaluated retrospectively. Vital signs and clinical findings were determined before interventions such as suctioning, antipyretic medication, oxygen support, and I.V. fluid. We included the patients with bronchiolitis treated with high flow nasal cannula therapy. Patients were divided in two groups: High flow nasal cannula therapy responders and non-responders. High flow nasal cannula therapy failure (non-responders) was defined as the need for escalation to another ventilation support: non-invasive ventilation or invasive mechanical ventilation. 

Results: A total of 84 infants (median age: 5 month; 25-75 percentile: 2-10 month; minimum: 6 weeks – maximum: 19 months; female/male: 25/59) with bronchiolitis were treated with high flow nasal cannula therapy. 23 of them (27.4%) were in non-responders group; 19 of them were intubated and mechanically ventilated. Underlying chronic disease, prior hospitalization due to bronchiolitis, prior admission to the pediatric intensive care unit, significant tachycardia (0-12 months> 160 / min, 12-24 months: 150 / min), physical examination findings of significant dehydration (5% or more), pH <7.30 and high pCO2 level (>45 mm Hg) were found more frequently in non-responders group (p <0.05). In the logistic regression analysis, underlying chronic disease (p: 0.031; OR: 4.677; 95%CI: 1.148-19.062), significant tachycardia (p: 0.015; OR: 5.088; 95%CI: 1.369-18.910), and significant dehydration (p: 0.038; OR: 3.811; 95%CI: 1.079-13.459) were the most significant parameters.

Conclusion: The presence of underlying chronic disease, significant tachycardia, and significant dehydration were the most powerful predictors of high flow nasal cannula therapy failure in children with bronchiolitis.


Dr Murat ANIL (Izmir, Turkey), Yuksel BICILIOGLU, Fulya KAMIT CAN, Ayse Berna ANIL, Esin ALPAGUT GAFIL, Gamze GOKALP, Emel BERKSOY
17:20 - 17:30 #11716 - OP062 High flow nasal cannula therapy in the pediatric emergency department; a prospective pilot study.
OP062 High flow nasal cannula therapy in the pediatric emergency department; a prospective pilot study.

 

Background and Objectives: High-flow nasal cannula (HFNC) is a reliable method of respiratory support that has demonstrated large utility in the pediatric population. HFNC may be able to avoid intubations in patients with respiratory distress. There is limited data about its use in the pediatric emergency department (PED). The aim of this study was to evaluate whether the use of HFNC therapy is associated with reduced respiratory distress and a decreased need for intubation in patients presenting to the PED.

Methods: This was a single –center prospective observational study conducted over six months  (October 2016 - March 2017) on children with severe respiratory distress (SRD) who commenced HFNC therapy in our PED. Baseline demographic and clinical data, as well as respiratory variables at baseline and various times after HFNC initiation during 24 h, were recorded. Therapy failure was defined as clinical deterioration in respiratory status after that requiring another form of non-invasive ventilation (nasal positive airway pressure (CPAP) or bilevel positive airway pressure (BiPAP)) or invasive ventilation (intubation) within 24 hours from the time of HFNC initiation. The rate of intubation, admisson to pediatric intensive care unit, therapy failure and predictors of therapy failure were also recorded.

Results: A total of 115 children commenced on HFNC therapy in PED during the study period. The median age was 12 months and 70% patients were male. The most common diagnosis was acute bronchiolitis (n=73, 63.5%) followed by pneumonia (n = 23, 20%) and asthma (n = 18, 15.7%). Seven-teen   patients (14.8%) failed HFNC therapy;10 required secondary invasive mechanical ventilation and 7 BiPAP.  Children who had higher initial respiratory score (RS)  and comorbodity were more likely to fail the HFNC therapy (p=0.001, p=0.039). HFNC significantly reduced the respiratory rate, heart rate and (RS) at 2 hours of admission (p<0.05). These improvements were observed as early as 15 min after the beginning of HFNC for respiratory rate and heart rate.

Conclusion: HFNC has a beneficial effect on clinical signs and respiratory score in PED patients with acute severe respiratory distress. It also significantly reduced the respiratory rate and heart rate at the beginning.


Dr Ali YURTSEVEN (İzmir, Turkey), Caner TURAN, Eylem Ulas SAZ
17:30 - 17:40 #11757 - OP063 HACOR score to predict in-hospital mortality for patients with type I and type II acute respiratory failure treated with non-invasive ventilation.
OP063 HACOR score to predict in-hospital mortality for patients with type I and type II acute respiratory failure treated with non-invasive ventilation.

OBJECTIVES: In a group of patients with type I and type II acute respiratory failure (ARF), treated with noninvasive ventilation (NIV), we tested if an early evaluation through a validated scale, using variables easily obtained at the bedside, can identify patients at high risk of adverse outcome.

METHODS: This was a retrospective study including all patients with ARF requiring NIV over a two-year period (January, 2014-July, 2016), admitted in an Emergency Department High-Dependency Observation Unit (ED-HDU). Clinical data were collected at baseline, 1 hour, and 24 hours; HACOR score (previously employed only in patients with hypoxemic respiratory failure) was calculated before NIV and after 1 hour and 24 hours of treatment. For prognostic analysis, the score was evaluated as continuous value and as dichotomized value (≤5 or >5, as suggested in the validation study). The primary outcome was in-hospital mortality, need of ICU admission and NIV weaning in a 48-hour time interval.

RESULTS: The study population includes 348 patients, mean age 77±15 years, 53% male gender. Most frequent admission diagnosis were pneumonia in 59% of patients, congestive heart failure in 34% and sepsis in 20%, which overlapped in some patients. Ninety-eight patients presented a Type I ARF and 250 a Type II ARF. In-hospital mortality was 33% in Type I ARF patients and 19% in Type II patients (p=0.012).  Compared with survivors, Type I non-survivors showed  comparable HACOR score before NIV (7.3±5.5 vs 5.9±2.9, p=NS), but higher score after 1-hour (6.8±6.4 vs 3.4±3.3, p=0.025) and 24-hour (6.2±5.0 vs 3.0±2.6, p=0.022) NIV treatment; moreover, HACOR score reduction during the first hour of NIV treatment was significantly higher in survivors compared with non survivors (-2.7±3.2 vs -0.7±3.7, p=0.016). Analysis for repeated measures showed a significantly more marked score reduction  in survivors compared with non-survivors (p=0.001). Compared with survivors, Type II non-survivors showed  higher HACOR score before NIV (8.5±5.0 vs 6.3±4.2, p=0.005) and after 1-hour (6.7±4.7 vs 3.9±3.3, p<0.001) and 24-hour (3.8±4.3 vs 1.7±2.0, p=0.002) NIV treatment. Analysis for repeated measures showed a significantly more marked score reduction  in survivors compared with non-survivors (p=0.001). Compared with patients with HACOR ≤5, Type II patients with HACOR score >5 showed a significantly higher mortality rate at every evaluation point (before NIV: 68 vs 48%, p=0.026; 1-hour: 55 vs 26%, p<0.001; 24-hour: 18 vs 5%, p=0.009); analysis with dichotomized values did not show significant differences among patients with Type I ARF.     

CONCLUSIONS: among patients with Type II respiratory failure , a Hacor score value >5 was significantly associated with an increased mortality rate; among Type I ARF patients, patients with adverse outcome showed significantly worst score value compared with patients with a good prognosis. 


Laura GIORDANO, Simona GUALTIERI (Florence, Italy), Arianna GANDINI, Lucia TAURINO, Monica NESA, Chiara GIGLI, Alessandro COPPA, Francesca INNOCENTI, Riccardo PINI
Kokkali
17:40

"Monday 25 September"

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A25
17:40 - 18:45

Award Ceremony

Moderators: Dr Thomas BEATTIE (Senior lecturer) (Edinburgh, United Kingdom), Felix LORANG (Consultant) (Erfurt, Germany), Youri YORDANOV (Médecin) (Paris, France)
17:40 - 17:45 #11133 - OP121 Home treatment of patients with pulmonary embolism: comparison of the performance of three clinical rules in daily clinical practice.
OP121 Home treatment of patients with pulmonary embolism: comparison of the performance of three clinical rules in daily clinical practice.

Background  

Recent guidelines suggest home treatment for patients affected by pulmonary embolism (PE) judged to be at low risk of adverse clinical outcome. Several clinical rules have been proposed but studies aimed to compare their efficiency and safety in daily clinical practice are lacking. 

Objectives  

We evaluated the efficiency and safety of PESI, sPESI scores and Hestia criteria in the identification of PE patients candidate to home treatment and compared them with clinical gestalt.  

Methods  

Consecutive adult patients with objectively diagnosed PE were prospectively included in the study. All data requested in PESI, sPESI and Hestia scores were collected prospectively. Patients were managed according to the clinical gestalt of the attending physician, independent of the results of clinical rules. The primary outcome was a composite of all-cause mortality, venous thromboembolic recurrence with or without hemodynamic collapse or major haemorrhage within 30 days from inclusion. Efficiency was the prevalence of low risk patients and safety the incidence of primary outcome in the low risk group according to each stratification model. 

Results  

We included 277 patients with a median age of 75 years, 52.7% were females. After initial assessment, including right ventricular dysfunction evaluation, 123 (44.4%) patients were judged to be at low risk and discharged within 48 hours from presentation. Six (4.9%, 95% CI 1.8-10.3%) of these patients reached the primary outcome.  

Similarly to clinical gestalt, Hestia criteria identified 121 (43.6%) low-risk patients, whereas both PESI and sPESI identified a significantly lower proportion of low-risk patients (24.9% and 19.1% respectively, p< 0.05 for both). Primary outcome incidence was 7.3% (95% CI 2.4%-16.1%), 7.6% (95% CI 2.1-18.2%) and 4.1% (95% CI 1.4-9.4%) in PESI, sPESI and Hestia low-risk groups respectively, without significant differences among prognostic models and in comparison to clinical gestalt.  

Conclusions 

In our cohort, Hestia criteria showed higher efficiency and similar safety in identifying low-risk patients when compared to PESI and sPESI scores. Clinical rules did not show better performance than clinical gestalt in identifying PE patients candidate to home-treatment. 


Valerio STEFANONE, Peiman NAZERIAN, Cosimo CAVIGLIOLI, Michele BAIONI, Chiara GIGLI, Gabriele VIVIANI, Stefano GRIFONI, Simone VANNI (Florence, Italy)
Top scoring Abstract 1
17:45 - 17:50 #11370 - OP122 Impact of using the HEART score in chest pain patients at the emergency department: a stepped wedge, cluster randomized trial.
OP122 Impact of using the HEART score in chest pain patients at the emergency department: a stepped wedge, cluster randomized trial.

Background: The HEART score is a simple instrument to stratify chest pain patients according to their probability of having an acute coronary syndrome, but its impact in daily practice is unknown. The HEART-Impact trial was designed to measure the impact of its use on patient outcomes and use of health care resources.

Methods: In a stepped wedge, cluster randomized trial, chest pain patients presenting at emergency departments (ED) were included in nine hospitals in the Netherlands  between 2013 and 2014. All hospitals started with “usual care” and over time hospitals consecutively switched to “HEART care”, during which treating physicians calculated the score for each patient to guide patient management. For safety, a non-inferiority margin for major adverse cardiac events (MACE) was set. Other outcomes included use of health care resources, quality of life, and cost effectiveness. Trial registration: ClinicalTrials.gov 80-82310-97-12154 (closed).

Results: A total of 3,648 patients were included, 1,827 receiving usual care and 1,821 HEART care. Six-week incidence of MACE during HEART care was 1.3% lower than during usual care (upper limit one sided 95% CI: +2.1%, not exceeding the non-inferiority margin of +3%). In low-risk HEART patients, incidence of MACE was 2.0% (95% CI: 1.2 to 3.3%). No statistically significant differences in early discharge, readmissions, recurrent emergency department visits, outpatient visits or visits to general practitioner were observed.

Conclusion: Using the HEART score during initial assessment of chest pain patients is safe but the impact on health care resources was limited possibly due to non-adherence to management recommendations. Physicians were hesitant to refrain from admission and diagnostics in patients classified as low-risk by the HEART score.


Judith POLDERVAART (Utrecht, The Netherlands), Johannes REITSMA, Barbra BACKUS, Erik KOFFIJBERG, Rolf VELDKAMP, Monique TEN HAAF, Yolande APPELMAN, Herman MANNAERTS, Jan-Melle VAN DANTZIG, Madelon VAN DEN HEUVEL, Mohamed EL FARISSI, Benno RENSING, Nicolette ERNST, Ineke DEKKER, Frank DEN HARTOG, Thomas OOSTERHOF, Giske LAGERWEIJ, Eugene BUIJS, Maarten VAN HESSEN, Marcel LANDMAN, Roland VAN KIMMENADE, Luc COZIJNSEN, Jeroen BUCX, Clara VAN OFWEGEN-HANEKAMP, Jacob SIX, Maarten-Jan CRAMER, Pieter DOEVENDANS, Arno HOES
Top scoring Abstract 2
17:40 - 18:45 #11731 - OP123 Addition of magnesium sulphate to the femoral block: preliminary results.
Addition of magnesium sulphate to the femoral block: preliminary results.

Introduction:  Due to its N-methyl-D-aspartic (NMDA) receptor antagonist effect in peripheral neurons, some studies suggest the potential analgesic effect of magnesium sulphate (Mg2+).On the other hand, according to our daily practices, the classic femoral block seems to have a short duration of action.The objective of our study is to show the potentiating effect of the addition of SMg to the xylocaine in the WINNI’s femoral block in traumatology. Methods: A prospective study including all patients aged> 16 years and suffering from a medio-diaphyseal femoral fracture or a knee wound. After patient consent, randomization was carried among 3 groups: A (15 ml xylocaine 2% + 5 ml SMg 10%), B (15 ml xylocaine + 5 ml S.Phy 0.9%), C (15ml SMg + 5ml S.Phy 0.9%). The severity of the pain was assessed using EVA at 0 min, 15 min, 30 min, 40 min, 50 min, 60 min and then every 60 min until the first six hours after the femoral block. If  EVA> 5 after 15 min local anesthetic injection, titration of morphine as a rescue analgesic is recommended.  Jujement criteria are the duration of the sensory block, the duration of tolerance of pain, the rate of failure of analgesia and the appearance of side effects.  Results:  We included 28 patients (39.3%  are men) with a median age of 71.4 +/- 16 years. The most frequent occurrence of the fracture was the fall (68%). The average duration of the sensory block was 220 + /- 70 min, 125 +/ - 70 min, 14.5 +/ - 28.3 min respectively for group A (n =10), B (n =8) and C (n=10) with a significant difference.  The average duration of tolerance of pain was 274 +/ - 103min, 148.74 +/ - 92 min and 18 +/ - 6.3 min respectively for group A, B and C with a significant difference. During the study we did not note any side effect. Conclusion: Mg sulphate appears to have a potentiating effect on the duration and efficacy of the WINNI’s femoral block without added side effect.


Rabiaa KADDACHI, Asma ZORGATI, Wael CHABAANE, Achref HAJ ALI, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
17:55 - 18:00 Introduction of Falck Foundation and Top scoring Pre-Hospital Abstract. Rune ANDERSEN (OTHER) (Keynote Speaker, Arhus C, Denmark)
18:00 - 18:05 Sophus FALCK Prize abstract presentation.
18:05 - 18:10 EUSEM YEMD Fellowship presentation. Riccardo LETO (Emergency physician) (Keynote Speaker, Genk, Belgium)
18:10 - 18:15 YEMD Fellowship certificate hand-over.
18:15 - 18:20 EUSEM Best Abstract announcement and certificate hand over.
18:20 - 18:25 EMERGE EBEEM announcement. Ruth BROWN (Speaker) (Keynote Speaker, London)
18:25 - 18:30 European Board Examination of Emergency Medicine diplomates ceremony.
18:30 - 18:35 Best performance EBEEM Part A certificate.
18:35 - 18:40 Best performance EBEEM Part B certificate.
18:40 - 18:45 EMDM Diploma ceremony. Pr Francesco DELLA CORTE (Head of Emergency Department) (Keynote Speaker, Novara, Italy)
Trianti Hall
Tuesday 26 September
08:30

"Tuesday 26 September"

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A30
08:30 - 09:00

Herman Delooz Lecture

Moderator: Pr Rick BODY (Professor of Emergency Medicine) (Manchester)
08:30 - 09:00 Do we still need 'Tintinallis' in 2017? Judith TINTINALLI (Professor) (Speaker, Chapel Hill NC, USA)
Trianti Hall
09:10

"Tuesday 26 September"

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A31
09:10 - 10:40

Disaster Medicine III (Cutting Edge)
European Response to Disaster

Moderators: Pr Francesco DELLA CORTE (Head of Emergency Department) (Novara, Italy), Benoît VIVIEN (Adjoint du Chef de Service du SAMU de Paris, Responsable du SAMU Pédiatrique Régional IDF) (Paris, France)
Coordinator: Dr Abdo KHOURY (Coordinator, Besançon, France)
09:10 - 09:40 French Reserve Corps. Sophie MONTAGNON (Praticien hospitalier) (Speaker, New York, France)
09:40 - 10:10 Turkish Response Team. Al BEHCET (faculty speaker) (Speaker, Gaziantep, Turkey)
10:10 - 10:40 Euro Corps: the European Response. Massimo AZZARETTO (Medico Specialista) (Speaker, Lugano, Switzerland)
Trianti Hall

"Tuesday 26 September"

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B31
09:10 - 10:40

Cardiovascular (How To)
Panel discussion

Moderators: Barbra BACKUS (Emergency Physician) (Rotterdam, The Netherlands), Pr Rick BODY (Professor of Emergency Medicine) (Manchester)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
09:10 - 10:40 Panel discussion. Pr Rick BODY (Professor of Emergency Medicine) (Speaker, Manchester), Barbra BACKUS (Emergency Physician) (Speaker, Rotterdam, The Netherlands), Ian STIELL (Physician) (Speaker, Ottawa, Canada), Martin THAN (Speaker, New Zealand), Pr Martin MÖCKEL (Head of Department, Professor) (Speaker, Berlin, Germany)
Mitropoulos

"Tuesday 26 September"

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C31
09:10 - 10:40

Infectious Disease & Sepsis (Game Changers)

Moderators: Laura HOWARD (United Kingdom), Cao YU (emergency) (Chengdu, China)
Coordinator: Christoph DODT (Coordinator, München, Germany)
09:10 - 09:40 Consensus Definitions for Sepsis and Septic Shock Advantages and Disadvantages. Luis GARCIA-CASTRILLO (ED director) (Speaker, ORUNA, Spain)
09:40 - 10:10 Sepsis day and a National Registry of sepsis in Hungary. Peter KANIZSAI (lead emergency physician) (Speaker, Pécs, Hungary)
10:10 - 10:40 Implementation of sepsis guidelines in the ED. Kurt ANSEEUW (Medical doctor) (Speaker, Antwerp, Belgium)
Banqueting Hall

"Tuesday 26 September"

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D31
09:10 - 10:40

YEMD - Eye-opener Quiz

Moderators: Blair GRAHAM (Research Fellow) (Plymouth, United Kingdom), Riccardo LETO (Emergency physician) (Genk, Belgium)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
09:10 - 09:30 Spot Diagnosis. Tony KAMBOURAKIS (Director Medical Services) (Speaker, Melbourne, Australia)
09:30 - 09:50 ECG Conundrum. Blair GRAHAM (Research Fellow) (Speaker, Plymouth, United Kingdom)
09:50 - 10:10 Things you definitely should (not!) know. Basak YILMAZ (Faculty) (Speaker, BURDUR, Turkey)
10:10 - 10:30 For the NERDS. Incifer KANBUR (Assistant doctor) (Speaker, Istanbul, Turkey)
Skalkotas

"Tuesday 26 September"

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E31
09:10 - 10:40

Nursing session 1

Moderators: Marielle DEKKER (The Netherlands), Door LAUWAERT (Manager) (BRUSSELS, Belgium)
09:10 - 09:40 The impact of medical specialist staffing on emergency department patient flow and satisfaction. Christien VAN DER LINDEN (Clinical Epidemiologist) (Speaker, The Hague, The Netherlands)
09:40 - 10:10 Why we should implement a trauma protocol in ED. Georgios PAPAGEORGIOU (Nurse) (Speaker, Nicosia, Cyprus)
10:10 - 10:40 Nonfulfilled needs of the geriatric emergency patient -The role of GEM Nurse in the interprofessional team. Thomas DREHER-HUMMEL (Nurse) (Speaker, Basel, Switzerland)
MC-3

"Tuesday 26 September"

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F31
09:10 - 10:40

Free Papers Session 8

Moderators: Anthony GERASKLIS (Greece), Youri YORDANOV (Médecin) (Paris, France)
09:10 - 09:20 #11171 - OP064 Clinical characteristics of 2013 Haiyan typhoon victims presenting to the Belgian First Aid and Support Team.
OP064 Clinical characteristics of 2013 Haiyan typhoon victims presenting to the Belgian First Aid and Support Team.

Objectives

On November 8, 2013, the central Philippines islands were struck by typhoon Haiyan (Yolanda), damaging many local hospitals and disrupting acute and regular healthcare. The Belgian First Aid and Support Team erected a type 1 field hospital and water purification unit in Palo (south of Tacloban) to temporarily replace the damaged local healthcare. This study aims to describe the diagnoses encountered, and treatment provided by the Belgian team. Hypothesis is that besides disaster-related trauma, medical problems emerge soon, emphasising the importance of an appropriate composition of Emergency Medical Teams and their supplies.

Methods

Using a descriptive observational study design, all patients presenting to the Belgian field hospital were retrospectively reviewed. Each patient had an individual paper medical record that included gender, age, triage chief complaint, all secondary complaints, diagnosis, management and possible referral information. These were compared with a control group of patients from the same area and season, but from another year.

Results

All 1267 patients triaged, examined and treated in the field hospital, were included and analysed. Almost 28% suffered from injury, but the most important part of patients rather presented with medical diseases (64%), particularly respiratory (31%), dermatological (11%) and digestive (8%). The remaining 8% presented for follow-up, mental problems or pregnancy related issues. Most (53%) of the patients did not present with direct disaster-related acute pathology. More than 59% showed signs of infection within two weeks after the event. Most frequently used treatments were wound care (47%), pain relief (33%), vitamins and minerals (31%) and antibiotics (29% of all patients). Procedures were needed for 9%, fluid therapy for 8%, and psychological support for 5%. Logistic regression analysis indicates that children younger than 5 are more at risk for infectious diseases (OR 18.8 CI 10.6-33.3), and for injury (OR 10.3 CI 6.3-16.8), and males are twice more prone to be injured than females (OR 2.1 CI 1.6-2.6).

Conclusions

These results reveal that one week after the acute phase of a typhoon, respiratory, dermatological, and digestive problems emerge to the prejudice of trauma. Most patients did not present with direct disaster-related but with less acute diseases. Young children are more at risk for injury and infectious diseases. These facts should be anticipated when composing Emergency Medical Teams and supplies to be sent to the disaster site. 


Dr Gerlant VAN BERLAER (Brussels - BELGIUM, Belgium), Frank DE JONG, Timothy DAS, Carlos PRIMERO GUNDRAN, Matthijs SAMYN, Geert GIJS, Ronald BUYL, Michel DEBACKER, Ives HUBLOUE
09:20 - 09:30 #11241 - OP065 Bystanders and volunteers in disasters, experience from the Brussels attacks.
OP065 Bystanders and volunteers in disasters, experience from the Brussels attacks.

Purpose: To examine what roles bystanders and volunteers can play during a disaster and to propose an action card for the (medical) incident commander to manage this often unutilised resource of manpower and knowledge.

Relevance: During the terrorist attacks in Brussels on March 22nd 2016 the advantages as well as the problems with bystanders and volunteers during disasters were encountered. Many lives were saved by bystanders by using simple bleeding control techniques and the application of tourniquets. Among the bystanders there were soldiers patrolling the national airport. Their knowledge of lifesaving first aid (e.g. the use of tourniquets), extrication and triage proved pivotal in the first aid rendered to the victims.

However there were also unsolicited medical volunteers arriving with unauthorised private ambulances who became more a liability than a fruitful resource. Drawn to the scene out of curiosity and desire to help, not only were they unfamiliar with the Incident Command System (ICS), but because of the fact they were not registered in the regular EMS system they didn’t have the appropriate means of communication and started freelancing in deciding what to do on site and where to take victims in unregistered ambulances.  

An updated version of a national medical emergency plan was recently published. Being updated with the terrorist attacks in mind, it still fails to recognize bystanders as first aid providers.

Methods: Review of existing literature and unstructured interviews with medical personnel who volunteered during the aftermath of the Brussels Airport attack and the national EMS director.

Results: It is a certainty that (untrained) bystanders are the first providers of help during disasters. During the Brussels attacks we have seen the benefits of bystanders performing lifesaving bleeding control techniques, extrication of entrapped victims, transportation of casualties away from the blast sites and comforting victims.

All too often bystanders and volunteers at a disaster site remain unused and kept outside a perimeter upon arrival of EMS services and police and a clear guideline on how to integrate bystanders and volunteers was and still is lacking in any existing medical emergency plan. However, coordination of highly motivated bystanders and volunteers by professional EMS personnel had a positive effect on reducing morbidity and mortality in the Brussels attacks.  

Conclusion:  Because regular EMS is initially disrupted, bystanders and volunteers can aid in immediate search and rescue and first aid to victims. Instead of discouraging, their desire to help should be encouraged and planned for in emergency plans. To reduce the risk of untrained bystanders and volunteers disrupting the official organised response an action card to aid onsite incident managers is proposed.


Kris SPAEPEN (Brussels, Belgium), Ives HUBLOUE
09:30 - 09:40 #11504 - OP066 Training method in Personal Protective Equipment donning and doffing.
OP066 Training method in Personal Protective Equipment donning and doffing.

Introduction

When working with infectious diseases of high consequences the simple act of donning/doffing Personal Protective Equipment (PPE) becomes a lifesaving procedure not only for the medical staff but for the thousands of people who depend on them. Previous studies have shown that donning and doffing skills may be insufficient even after training. That raises a question on how to properly train staff in PPE donning and doffing to maintain the long term competence of PPE donning and doffing?

This study assessed if there is a performance difference one month after training between a control group that received instructor training and a study group that had access to a video over the month to compare the traditional tutorial based teaching method in teaching PPE donning and doffing.

Methods

This was a randomized controlled trial pilot study of video versus instructor training. 21 medical students and junior doctors where divided into 2 groups by simple randomization. The control group received training with an instructor. This training involved a demonstration of donning and doffing of PPE. Students were then observed donning and doffing of PPE until satisfactory performance had been achieved. There was no other intervention until the day of the assessment. The video group watched a training video demonstrating proper donning and doffing. The video group was given the video to watch at home as many times as they wanted. The training video was made by the same nurse who conducted the instructor training, using the same equipment. After a 1month period, a doctor performed a blind evaluation of all control and study groups using an adjusted Donning and Doffing PPE Competency Validation Checklist 2014.

Results

19 participants attended assessment session after a month with 9 in a control group and 10 in the study group. The mean donning score was 86,5/100.  Mean score was 84,8 for the instructor group, and 88.0 for the video group.There was no statistically significant difference in the donning score between the video and instructor group (95% confidence interval for the effect: -7.7 to 9.5; p-value: 0.54). The mean doffing score was 76,4/100. The mean score for instructor group was 79.1 and 73,9 for the video group. There was no significant difference in the doffing score between the video and instructor group (95% confidence interval for effect: -7,6 to 18,0; p-value: 0.54).

Conclusion

The study results suggests that donning and doffing competencies are similar for those who were trained with an instructor to those who were trained with the video method.


Liva CHRISTENSEN (Køge, Denmark), Thomas BENFIELD, Jeffrey Michael FRANC
09:40 - 09:50 #11653 - OP067 The use of table-top simulation for team training in disaster events.
OP067 The use of table-top simulation for team training in disaster events.

Objective: To find out if a table-top team training program would positively affect perception towards teamwork, and their ability to recognize the presence and quality of team skills in disaster events.

Background: Disaster training involves coordination and communication between various units, which necessitates involvement of the whole chain of response simultaneously. Due to the strict hierarchy culture in Korea, it is not easy to train healthcare providers in teamwork. Hospitals in Korea performs large-scale disaster exercise which takes a lot of preparation and resources. It is also difficult to assess teamwork and communication during a large-scale disaster exercise. Table-top simulation enables you to look at the whole process and the advantage of reflective, repetitive, and safe learning environment, where effective feedback can be provided. Since table-top simulation allows people to go through the thinking process, this could be a good module to train people improving on teamwork competency.

Methods: The educational intervention consisted of a half-day workshop for selected 24 emergency residents and 24 emergency nurses. Participants were given lectures on incident command system and surge capacity. They were randomly mixed into 6 groups (8 participants per group, 4 residents and 4 nurses). Participants were assessed as a group before and after the intervention, which consisted of debriefing session, focusing on the 5 components of teamwork (Team Structure, Communication, Leadership, Situation Monitoring, and Mutual Support). Discussions were focused on breaking the barrier of hierarchy in a crisis situation. The correct number of triage, treatment, and teamwork aspects were assessed. Assessment of teamwork was done in two parts. One was self-assessment of perception of teamwork, the Teamwork Perceptions Questionnaire (TPQ), and the other was assessment of the team performances, the Team Performance Observation Tool (TPOT). Both tools were derived from the TeamSTEPPS® Project (5-point Likert scale). They were modified to fit our culture and translated to Korean. Content validity index was performed (0.94). All pre-to-post differences within subjects were analyzed with paired t tests. The statistical level of significance was set at 0.05.

Results: Correct triaging and treatment improved after training with table-top simulation. Under triaging improved as well, but over triaging seemed to increase. Pre- and post-intervention differences for the 5 sections of the TPQ and TPOT improved. All results were statistically significant (p<0.05).

Conclusion: Teamwork and communication has cultural different aspects. Therefore, carefully planned curriculum tailored to the trainees, and debriefing session including discussion on cultural aspect is important when training for teamwork. Table-top exercise can positively affect perception toward teamwork, and their ability to recognize the presence and quality of team skills in disaster events.


Jiyoung NOH (Seoul, Republic of Korea), Hyun Soo CHUNG
09:50 - 10:00 #11779 - OP068 Evaluation of a training program to professionalize young doctors in humanitarian assistance.
OP068 Evaluation of a training program to professionalize young doctors in humanitarian assistance.

INTRODUCTION

Well-prepared humanitarian workers are now more necessary than ever; simulation-based training and evaluation are essential for the preparation process. This study aimed to assess the efficacy of a training program developed by the Research Center in Emergency and Disaster Medicine (CRIMEDIM) in collaboration with the international organization Médecins Sans Frontières (MSF) to professionalize senior residents in humanitarian assitance.

METHODS

The first three levels of the Kirkpatrick’s evaluation model (Reaction-Learning-Behaviour) were assessed.The 8 participants of the third course edition (4 residents in emergency medicine, 3 in anaesthesia and 1 in pediatrics) were enrolled in the study; the median age was 31. Residents participated in an introductory phase, completed a 3 month e-learning course, attended a residential week and were deployed with MSF in Pakistan (1), Afghanistan (2), Democratic Republic of Congo (1), South Sudan (1), Central African Republic (2) and Yemen (1). Reaction was assessed through a Likert scale questionnaire. The three dimensions of Learning were evaluated separately through a pre and post test as follows: a multiple-choice test was used to assess knowledge, a Likert scale questionnaire was used to evaluate attitudes, and simulation-based performance tests (using the Ottawa Global Rating Scale-GRS) were used to assess skills. Total multiple-choice scores and GRS overall performance scores were considered as primary and secondary outcomes, respectively. Differences were assessed using paired t-­tests. P ­values of less than 0.05 were considered significant. Behaviour was assessed qualitatively at the end of students’ missions by their field supervisors through the MSF standard evaluation module. Supervisors were blind to the students’ participation in the training program.

RESULTS

Reaction: the delivery modality and residential course were highly appreciated. The average median score for the overall course was 5 (excellent). Knowledge: there was a significant improvement in the post-test multiple choice scores when compared to the pre-test scores (p = 0.0011). Skills: there was a significant improvement in the overall performance score (P = 0.000001). No differences were detected in attitudes scores. Behaviour: for most participants the following strengths were highlighted: compliance with MSF standards and principles, flexibility, good team working skills and cross-cultural sensitivity.Their professional competence was never questioned. All residents were recommended for future MSF missions.

CONCLUSIONS

Residents were highly satisfied with this training program and their knowledge and skills in low-resource simulated humanitarian environments improved after participation in the course. The implementation of this project represents a model of how academia can successfully partner with humanitarian aid organizations to increase professionalization within the humanitarian health sector.

 


Alba RIPOLL GALLARDO (Milan, Italy), Luca RAGAZZONI, Ettore MAZZANTI, Grazia MENEGHETTI, Jeffrey Michael FRANC, Francesco DELLA CORTE
10:00 - 10:10 #11824 - OP069 Stampede, or not a stampede – that is the question.
OP069 Stampede, or not a stampede – that is the question.

Study/Objective:

To quantify the frequency and intention with which “stampede” is used to describe types of mass gathering disasters

Background:

Hazard vulnerability analysis would identify “human stampedes” as high probability events at mass gatherings. Over 200 “stampedes” have occurred in the past 30 years. At the 2015 Hajj, at least 2000 pilgrims died in one of the deadliest mass gathering disasters in recent history. News and literature referenced the event as the “Hajj Stampede”, implying abruptly increased speed and mass panic.  At the crux of many of these events, however, is a dense, immobile crowd – not the uncontrolled mindless mass implied.

Methods:

The authors performed a systematic search of peer reviewed literature indexed in PubMed, EMBASE, and Web of Science. Studies were limited to human studies using the keyword stampede. Gray literature using “stampede” in the title or abstract in reference to mass gathering disasters were also reviewed.

 

Results:

Search strategy using the term “stampede” yielded 649 articles. After excluding those using the term 1) apropos computing, 2) as an acronym, or 3) colloquially, 61 remained which used the term in reference to mass gathering disasters. 29 of 61 articles describe a slow-moving, highly dense crowd. 12 articles cite sudden mass movement as the main trigger for the referenced disaster. The remaining 18 described both slow-moving crowds and sudden mass movement. Only three articles distinguished between crowd disasters caused by sudden movement and high density. Overall, “Stampede” was used in the same context as “crowd disaster”, “turbulence”, “quake”, “mass panic”, “crush”, and “trampling”.

Discussion:

It is important to distinguish between stampede and non-stampede events for the benefit of survivors and for mitigation strategies. Few articles describing stampedes actually involve speed anywhere in the description. The generic “stampede”, through suggesting a fast moving, irrational and culpable crowd, focuses on herding the masses rather than improving safe access or egress routes to the gathering site. We must stem the notion that these disasters are a whim of the crowd and work towards evidence-based engineered solutions. 


Sravani ALLURI (Boston, USA), Amalia VOSKANYAN, Ritu SARIN, Michael MOLLOY, Gregory CIOTTONE
10:10 - 10:20 #11965 - OP070 Disaster education in senior Flemish nursing students.
OP070 Disaster education in senior Flemish nursing students.

Introduction: Nurses can be confronted with disasters and the care for the patients resulting from these incidents, be it in - or prehospital or in their own environment. Are they educated to do so? Following worrisome results in a survey on this subject amongst medical students our study hypothesis is that nursing students aren’t educated at all.

Material and methods: To evaluate disaster education in Flemish nursing students an online survey on Disaster Medicine, training and knowledge and willingness to report was sent to students in the last year of basic nursing training. This reported knowledge was tested by a mixed set of 10 theoretical/practical questions. A similar survey was sent to students in the Bachelor-after-Bachelor (BAB) specialisation year of Emergency Medicine and Intensive Care.

 

Results: Preliminary results from the first responding educational basic training centers reveal a M/F ratio of 13/87 with 29% that state that they have had any disaster training what so ever. 25% state to have some knowledge on CBRN incidents. 42% are convinced that a basic training on disaster management should absolutely be included in the basic nursing curriculum. None of the respondents found it useless. Estimated knowledge on several disaster scenarios varied from 1.92/10 (dirty bomb) over 2.24/10 (nuclear) and 3.49/10 (Ebola) to 4.05/10 in highly contagious influenza pandemic. Self-estimated capability to deal with these incidents varied from 2.22/10 (dirty bomb) over 2.59/10 (nuclear) and 3.54/10 (Ebola) to 4.14/10 in mass shooting incidents. Willingness to report to work in these incidents was much higher and varied from 7.19/10 (dirty bomb) over 7.41/10 (Ebola) and 7.56/10 (nuclear) to 7.94/10 in mass shooting incidents. Some topics of the theoretical / practical case mix raise some concern. 64% directs potentially contaminated patients direct into the emergency department. 75% believes that iodine tablets protect against external radiation and 37% would use them as the first step in nuclear decontamination. 37% believes that chemical decontamination consists of a total body antidote spray in a civil defence cabin and only 20% would use a shower with water and soap. Up to 47% would rush unprotected into a traffic accident scene with active leakage from a tanker truck. Self-reported knowledge and capability in the BAB group did not differ from the basic students and also the willingness to report was similar. They had however a better score on the theoretical / practical case mix.

 

Conclusion: Our data support the hypothesis that Flemish nursing students are ill-educated in disaster management. Despite low estimated knowledge and capability there is a high willingness to report.


Luc MORTELMANS (Antwerp, Belgium), Harald DE CAUWER, Marc SABBE
10:20 - 10:30 #10986 - OP071 Comparison of the quality of two speech translators in emergency settings : a case study with standardized Arabic speaking patients with abdominal pain.
OP071 Comparison of the quality of two speech translators in emergency settings : a case study with standardized Arabic speaking patients with abdominal pain.

In the context of the current European refugee crisis, at the Geneva University Hospitals (HUG) the languages which caused most problems were in 2016 Tigrinya, Arabic and Farsi. Several researchers pointed out serious problems of quality, security and equitability when no communication is possible between the doctor and his patient. BabelDr (http://babeldr.unige.ch/) is a common project of Geneva University's Faculty of Translation and Interpreting (FTI) and HUG which aims at facing this problem. The BabelDr application is a flexible speech-enabled phrase-book. The linguistic coverage is organised into domains, centered around body parts (abdomen, chest, head, kidney). Each domains has a limited semantic coverage consisting of 2000-2500 canonical sentences, but users can use a wide variety of surface forms when speaking to the system. The translation is not automatic; the canonical forms are translated into the target languages by translation experts from the FTI, which guarantees the quality of translation. At runtime, the system matches the spoken doctor’s utterance to a canonical sentence and echoes it back to the source-language user, only producing a translation if the source-language user approves. 

We compared BabelDr with the statistical MT system Google Translate (GT) for the anamnesis in emergency settings. French speaking doctors were asked to use both systems to diagnose Arabic speaking patients with abdominal pain, based on two scenarios. For each scenario (appendicitis and cholecystitis), a patient was standardized by the HUG.  Participants were four medical students and five doctors from HUG, who each performed two diagnoses, one with BabelDr and one with GT. 

The translation quality was evaluated in terms of adequacy and comprehensibility by three Arabic advanced translation students. Adequacy was judged on a four point scale (nonsense/mistranslation/ambiguous/correct) and comprehensibility on a four point scale (incomprehensible/syntax errors/non idiomatic/fluent). For the BabelDr translations, 93% of doctor's interactions sent to translation were correct and 94% fluent at the majority judgements. For GT, we respectively obtained 38% and 38%. Inter-annotator agreement for both evaluations was moderate (Light's Kappa for adequacy: 0.483; for comprehensibility: 0.44). With Google Translate 5/9 doctors found the correct diagnosis, against 8/9 with BabelDr. The satisfaction of doctors was also higher with BabelDr than with Google Translate: doctors were more confident in the translation to the target language with BabelDr than Google Translate (1/9 negative opinion with BabelDr vs 8/9 in GT). They also think they could integrate BabelDr in their everyday practice in the emergency room, contrary to GT (1/9 negative opinion with BabelDr vs 5/9 with GT).These results tend to show that BabelDr is a promising tool for the task and that GT translations are insufficiently adequate, accurate and comprehensible for emergency settings. 


Herve SPECHBACH, Sonia HALIMI, Johanna GERLACH, Nikos TSOURAKIS, Pierrette BOUILLON, Herve SPECHBACH (Geneva, Switzerland)
10:30 - 10:40 #11056 - OP072 Predicting Hospital Admission at Emergency Department Triage: a comparison of natural language processing and neural network methodological techniques.
OP072 Predicting Hospital Admission at Emergency Department Triage: a comparison of natural language processing and neural network methodological techniques.

Background

Emergency department (ED) crowding and increasing ED utilization are well-recognized problems for patient care in the United States.  To what degree predictive analytic techniques can improve wait times and patient outcomes when employed early in the ED stay--specifically during the triage process--is not well described.  We created predictive models to compare logistic regression (LR) and multilayer neural network (MLNN) techniques to predict hospital admission/transfer or discharge following initial presentation to ED triage with and without the addition of natural language processing (NLP) to analyze patient-reported free-text information.

Methods

Using data from the National Hospital Ambulatory Medical Care Survey (NHAMCS), a cross-sectional probability sample of United States EDs from 2012 and 2013 survey years, we developed several models to predict patients’ disposition: hospital admission or transfer vs. discharge. We included patient characteristics which are immediately available after the patient presents to the ED following ED triage. We used this information to construct logistic regression and multilayer neural network models which included NLP and principal component analysis to incorporate the patient-reported reason for visit.  Ten-fold cross validation was used to test the predictive capacity of each model and c-statistics / receiver operating curves (AUC) were calculated to compare these predictive models.

Results

Of the 47,200 ED visits from 642 hospitals, 6,335 (13.4%) resulted in hospital admission (or transfer). A total of 48 principal components were extracted by NLP from patient’s reason for visit, which explained 75% of the overall variance for hospitalization. In the model excluding patient’s free-text reason for visit, the AUC was 0.824 (95% CI 0.818-0.830) for LR and 0.823 (95% CI 0.817-0.829) for MLNN. When patients’ free text reasons for visit were included, the AUC increased to 0.846 (95% CI 0.839-0.853) for LR and 0.844 (95% CI 0.836-0.852) for MLNN.

Conclusions

The predictive accuracy of hospital admission/transfer or discharge for patients who presented to ED triage improved with the inclusion of free text data from patients’ reason for visit regardless of modeling approach.  The predictive ability of these models was generally quite good at predicting disposition with the limited information immediately available during the triage process. Natural language processing and multilayer neural networks provide ways to incorporate patient-reported free-text information when predicting various outcomes that are important in providers’ clinical decision-making. 


Justin SCHRAGER, Rachel PATZER, Xingyu ZHANG, Joyce KIM, Justin SCHRAGER (Atlanta, USA)
Kokkali
10:45

"Tuesday 26 September"

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PH4 - S1
10:45 - 11:05

E-Poster Highlight Session 4 - Screen 1

Moderators: Yonathan FREUND (PUPH) (Paris, France), Dr George NOTAS (DOCTOR) (HERAKLION, Greece)
10:45 - 10:50 #11217 - Risk factors associated with difficult venous access in adult emergency department patients.
Risk factors associated with difficult venous access in adult emergency department patients.

Background:

Establishing vascular access is one of the most common procedures carried out in the emergency department (ED) and a high priority for the care of a critically ill and unstable patients.

It is generally easy to realize, nevertheless, the difficulty or the impossibility of this access is a challenge of any emergency physician. Difficult venous access (DVA) can cause delays in diagnosis and treatment implementation in critically ill patients.

Methods:
This was a prospective, observational study conducted in the ED and in prehospital care which enroll adult patients undergoing intravenous (IV) placement. The primary outcome was DVA, defined as 2 or more IV attempts to establish IV access. Univariate analyze for factors predicting DVA was performed using Pearson's chi-squared test.

Results:

A total of 500 patients were enrolled, of which 90 (18%) met the criteria for DVA. In the univariate analysis, 5  conditions were significantly associated with DVA: elderly (p=0.015), history of chemotherapy (p=0.008), women (p=0.006), obesity (p=0.001), and cardiac arrest (p=0.006).

The most common alternative approach to DVA were: changing the operator (66 patients), change of site's puncture (85 patients), smaller IV catheter size (19 patients).

Discussion:
Difficult venous access is a common problem in the ED that can be frustrating for both patients and providers.  The prevalence of DVA was 18%, which is similar  to previous studies reporting a range of  from 10 to 40%.

Patients who are likely to present with challenges to peripheral intravenous line insertion often can be identified by certain risk factor (elderly, women, chemotherapy, obesity, cardiac arrest status). Several factors previously thought to be associated with DVA such as diabetes, IV drug abuse, sickle cell disease, dialysis, history of frequent  admissions in ED were not found to be significant in the current study. One issue with this finding is that these other conditions typically associated with DVA were not significant in our study. Future research is needed to confirm and expand these findings and to develop interventions to improve IV insertion skills and outcomes.


Majdi OMRI, Hajer KRAIEM (Sousse, Tunisia), Amal BACCARI, Nizar NAOUAR, Sami BEN AHMED, Mohamed Aymen JAOUADI, Mounir NAIJA, Naoufel CHEBILI
10:50 - 10:55 #11242 - Headaches and post-traumatic stress disorder: a 3-year prospective monocentric survey.
Headaches and post-traumatic stress disorder: a 3-year prospective monocentric survey.

INTRODUCTION: Post-traumatic stress disorder (PTSD) is an adjustment disorder that can occur after exposure to potentially traumatic event. Joint headaches are often observed in the accompanying painful complaints. Since the relation between the association of headaches and a PTSD has not been insufficiently studied, our primary objective was to study the incidence and the impact of headaches in a PTSD; the secondary objective was to analyze the influence of the PTSD's treatment on these headaches.

MATERIALS: Prospective observational monocentric survey conducted between January 2013 and December 2015. Inclusion criteria: patients suffering from PTSD after exposure to situations with high traumatic potential (armed attacks, road accidents, etc.) and voluntary for the self-administered questionnaire. Study variables: epidemiological data, headaches and their type before and after the diagnosis of PTSD (ICHD scale), impact on the quality of life (HIT6 score), on mood (POMS scale), severity of the PTSD (PCLS scale) and treatments received. Statistics: Fisher's exact test and Chi2 tests (qualitative variables), Mann-Whitney U-test (quantitative variables), Spearmans correlation (score comparison), all significant if p<0.05.

RESULTS: Over a period of 3 years, 101 patients (90% men) were included in 437 questionnaires sent (23.1%). The median age was 32 [27;39] years. The overall incidence of headaches was 54.5% (N=55) and the post-PTSD incidence was 36.6% (N=18). The HIT-6 score was 58.8 +- 8,3 with a major impact in 56.4% (N=31) of the cases. The severity of PTSD was correlated to PCLS scale same as the intensity of headaches on HIT-6 score (Spearman’s rho=0.35, p=0.009). In the post-PTSD time, tension headaches were predominantly found (45.5%, N=25). Associated head trauma was not an aggravating factor (p=0.3). Patients suffering from headaches were more often treated for PTSD (p=0.02). The pattern of mood, particularly anger and depression, showed a higher average score in headache patients (p=0.039).

DISCUSSION: Headaches should be recognized in the cohort of painful complaints that may accompany PTSD, as a potential indicator of its severity. Wartime’s pathology inviting itself particularly in the French territory after the attacks of 2015, the training and  multidisciplinary care approach by the health care givers are more than ever important and relevant.


Julie DEFRANCE, Stéphane FOUCHER, Jean-Pierre SIMSON, Marion TROUSSELARD, Eric RAMDANI, Dr Abdo KHOURY (Besançon), Christophe LABLANCHE, Hugues LEFORT, Laurent GUILLOTON
10:55 - 11:00 #11512 - Sensitivity of SOFA and qSOFA scores for critical illness among ED infected patients.
Sensitivity of SOFA and qSOFA scores for critical illness among ED infected patients.

Background: We designed this study to assess the validity of the Sequential ( sepsis - related) Organ Failure Assessment (SOFA) score of 2 points or more and quick SOFA (qSOFA) ≥ 2 for identifying emergency department (ED) infected patients with critical illness.

Methods: This prospective observational study will be performed in the ED university -affiliated tertiary care hospital. Adults patients will be included in this study if they had the following criteria: older than 18 years, present in our ED with infection probable or documented, are competent to give informed consent, and to be admitted to the hospital's service. Collected data includes age, sex, vital signs, origin of infection, SOFA and qSOFA score, and outcome. The primary outcome was the incidence of a critical illness defined as a stay in the intensive care unit of 72 hours or longer or hospital mortality. The ability of SOFA score ≥ 2 and qSOFA score ≥ 2 in predicting critical illness was evaluated by determining the sensitivity, specificity, positive and negative predictive values, and the area under the Receiver Operating Characteristics (ROC) curves. 

Results: We included 255 patients with a median age of 68 years (25 - 75% IQR: 59-79) who were admitted for infection. Pulmonary and urinary tracts were the most frequently infection. The frequency of patients with SOFA ≥ 2 AND qSOFA ≥ 2 were respectively 76% and 23%. The sensitivity of SOFA ≥ 2 for predicting critical illness was 93% (95% confidence interval (CI), 83% -98%) and the area under the ROC curve was 0.78 (95% CI, 0.71 - 0.85). The sensitivity of qSOFA was 49% (95% CI, 36% - 62%) and the area under the ROC curve was 0.76 (95% CI, 0.69- 0.83).

Conclusion: In ED the SOFA score was more sensitive than qSOFA for predicting critical illness.


Wiem KERKENI, Wiem KERKENI (DAX), Samia BETOUT, Nahla JERBI, Insaf DLALA, Yosra YAHYIA, Ahlam BAKHROUF, Maroua BEN ABDALLAH, Hajer SAID, Ikram FETHALLAH, Soudani MARGHLI
11:00 - 11:05 #11575 - qSOFA, SIRS and early warning scores for predicting sepsis outcomes in emergency room.
qSOFA, SIRS and early warning scores for predicting sepsis outcomes in emergency room.

Background. Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. Sepsis contributes to up to half of hospital deaths and is responsible for the utilization of a significant proportion of healthcare resources. Early diagnosis and quick interventions are associated with better outcomes. Early warning scores (EWS) are physiological monitoring systems that are used for detection of acutely deteriorating patients. The recently updated definitions of sepsis proposed the Quick Sequential (Sepsis-related) Organ Failure Assessment (qSOFA) score in order to consider diagnosis of sepsis in the emergency department and on the wards. Physiological EWS including the National Early Warning Score (NEWS) and the Modified Early Warning Scores (MEWS) have been shown to predict mortality and escalation of care in patients admitted to hospital. SIRS criteria are usually criticized for their poor specificity. MEWS and the NEWS are commonly implemented in clinical practice outside the ICU. Our study sought to compare qSOFA, SIRS, NEWS and MEWS scores to identify high-risk septic patients in the Emergency Room (ER).

Methods. All patients admitted to the ER meeting criteria for suspicion of sepsis during 2016 September-December were included in the retrospective single-centre study. qSOFA, SIRS, MEWS and NEWS scores were compared for predicting death and ICU-stay.

Results. In total, 64 patients (38 male (59.4%), 26 female (40.6%) were admitted due to suspected sepsis during September – December of 2016. The mean age was 64.05 ± 18.63 years. 20.3% (n=13) patients died. Discrimination for in-hospital mortality or ICU-stay was highest for NEWS (AUC 0.738 [95% CI 0.612-0.841], p=0.001), followed by qSOFA ( AUC 0.686 [ 95% CI 0.557-0.797], p=0.003),  MEWS (AUC 0.654 [95% CI 0.523-0.769], p=0.027) and  SIRS (AUC 0.635 [95% CI 0.504-0.752], p=0.035) (p >0.05 for all pairwise comparisons). Using a patient’s highest non-ICU score, ≥2 SIRS had a sensitivity of 15.38% and specificity of 100% for the composite outcome compared to 7.69% and 96% for NEWS ≥8 and 0% and 98% for MEWS ≥5. And these results are in contrary to most of the studies. Highest sensitivity and specificity of MEWS was for >2 scores (38.46% and 76%), for NEWS - >4 scores (69.23% and 70%), for SIRS - >1 (84.62% and 40%). The mean time spent in ER was 287 min (IQR 188-403). The median hospitalization time was 12.5 days (IQR 8-18).

Discussion. Our study showed, that even though qSOFA showed higher discrimination for in-hospital mortality or ICU-stay than MEWS and SIRS criteria, NEWS criteria showed better one. On the other hand, the diagnostic test value is still poor, same as SIRS. Study needs further investigation in behalf of objection to other studies on this matter.


Ruseckaitė RENATA, Smiltė KOLEVINSKAITĖ (Vilnius, Lithuania)
E-Poster Area

"Tuesday 26 September"

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PH4 - S4
10:45 - 11:05

E-Poster Highlight Session 4 - Screen 4

10:45 - 10:50 #9857 - Value of physiological scoring systems in prediction of long-term mortality in traumatic brain injury patients.
Value of physiological scoring systems in prediction of long-term mortality in traumatic brain injury patients.

Background: Rapid acute physiological score (RAPS) and Worthing physiological scoring system(WPSS) models have received much attention in recent years. Yet, the value of these systems in outcome prediction of traumatic brain injury (TBI) patients has not been assessed. Therefore, the present study was designed aiming to compare the value of the 2 mentioned models in prediction of 6-month mortality of head trauma patients.
Methods: The present study is a diagnostic accuracy one evaluating head trauma patients presenting to emergency department. Each patient had a WPSS score and a RAPS score, and then the discriminatory powers of the 2 models with 95% confidence interval (95% CI) were compared.
Results: Data of 735 head trauma patients was assessed. During the 6-month follow-up, 48 (6.53%) patients died. Area under the curve of RAPS and WPSS in prediction of 6-month mortality were 0.93 (95% CI: 0.88-0.98) and 0.97 (95% CI: 0.96-0.98), respectively. The 2 evaluation models had similarvalue in prediction of mortality in head trauma patients (p=0.10). The best cut off point for RAPS and WPSS in prediction of trauma patients’ mortality was 5 and 2, respectively. RAPS had sensitivity and specificity of 89.58 (95% CI: 76.56-96.10) and 85.15 (95% CI: 82.22-87.68), respectively. Sensitivity and specificity of WPSS model were 100.0 (95% CI: 90.77-100.0) and 87.92 (95% CI: 85.19-90.21), respectively.
Conclusion: Findings show that there is a significant correlation between physiological factors on admission and mortality of head trauma patients. In addition, it was determined that RAPS and WPSS physiological scoring systems have high value in prediction of mortality following TBI.

Sahar MIRBAHA, Alireza BARATLOO, Alaleh ROOHIPOUR, Hamidreza HATAMABADI (Tehran, Islamic Republic of Iran)
10:50 - 10:55 #10508 - Door-to-Balloon in patients with ST Elevation Myocardial Infarction: Minding the gap.
Door-to-Balloon in patients with ST Elevation Myocardial Infarction: Minding the gap.

Mor Saban,  Efrat Dagan,  Aziz Darawsha, Rabia Salama

Background. A fast and correct identification of ST Elevation Myocardial Infarction (STEMI) in the Emergency Department (ED) significantly correlates to decrease morbidity, mortality and related complications in patients with chest pain. Yet, delayed diagnosis in patients with STEMI still represented a blind spot in the assessment of quality health care indicators.

Aim. To evaluate a 'fast-track' intervention intended to shorten Door-to-Balloon waiting times in patients presenting to the ED triage with STEMI.

Methods. In 2016, a 'fast track' intervention program for patients with chest pain was implemented in the ED at Rambam Health Care Campus. We determined a set of clinical guidelines for patients' assessment as follows: 15’ to triage, 10’ to ECG, 40’ for physician assessment, 60’ waiting time for decision and 90’ to catheterization lab (Door-To-Balloon-Time). The program was comprised of four steps: 1. Laying the patient immediately. 2. Marking the chart with a dedicated sticker 3. Assessing time-lags according defined clinical guidelines. 4. Signing the ECG and the dedicated sticker by a physician.
A retrospective-archive study was conducted between January 2015 and December 2016, to evaluate the intervention program achievements. We compared the adherence to clinical guidelines between all STEMI patients (n=140) who were attending to ED before (i.e during 2015, n=60) and after (i.e during 2016, n=80) implementing the intervention.  A lift chart and receiver operating characteristic
(ROC) curve were used to determine the optimal time lags in ED for achieving the objective of 60 minutes for evaluating the patients in ED.
Results. After implementing the intervention more patients have reached ECG evaluation within 10’ (57.5%) compared to pre- intervention (40%) (p=0.04); and more patients were stayed at ED less than 60’ (87.5% and 63.3%, respectively, p=0.01).
It clearly appears that post- compared to pre- intervention, less time lags (in minutes) were measured in patients who their clinical guidelines were not achieved before the program. This was found for physician assessment (70.25±30.24 vs. 52.86±13.51, respectively, p=0.05), for total waiting time in ED (126.18±59.63 vs. 72±9.67, respectively, p<0.001) and time to balloon (164.61±53.89 vs. 125±32.25, respectively, p<0.01). Interestingly, The ROC curve show that patients who were treated at ED according to the three clinical guidelines (15' for the nurse, 10' for E.C.G and 40'  for the Physician), had the largest probability to uphold the 60 minute waiting time in ED (AUC=0.98).
Conclusions. A ‘fast-track’ management for patients with chest pain providing early diagnosis of STEMI and shortened the waiting time for catheterization. The findings call for implementing programs for identifying patients at risk for STEMI in ED triage and programs’ interventions to reduce time lags for reperfusion for these patients at risk as fast as possible.


Saban MOR (Zychron Yaakov, Israel)
10:55 - 11:00 #11167 - The simplified Pulmonary Embolism Severity Index and HESTIA rule to identify eligible patients with pulmonary embolism for outpatient management.
The simplified Pulmonary Embolism Severity Index and HESTIA rule to identify eligible patients with pulmonary embolism for outpatient management.

Background: The management of pulmonary embolism (PE) has evolved over the past decade. Henceforth, outpatient treatment is an option for selected patients at low risk of complications. To assist clinician in identifying those patients, several rules have been proposed. The most validated to date are the Pulmonary Embolism Severity Index (PESI) or its simplified version (sPESI) stratifying patients according to their mortality risk and the the HESTIA rule based on a list of exclusion criteria, each one requiring inhospital care. Both strategies are used in clinical practice, but very few studies confront them.

Aim: To compare the proportion of patients eligible for outpatient management according to the sPESI and HESTIA rule.

Methods: This is a retrospective monocentric study. All patients with confirmed PE through CT scan or V/Q scan within 48 hours after Emergency Department admission were included. Medical records were retrieved to determine the sPESI score and HESTIA criteria at admission. Patients were considered suitable for outpatient management according to the sPESI if it was equal to 0, or if none of the criteria were met for HESTIA rule.

Results: 105 patients were included. HESTIA rule and the sPESI did not significantly differ on the proportion of patients suitable for outpatient management, respectively 45.7% [36.5-55.2] and 39.1% [30.3-48.6], p = 0.328. However, taking into account medical conditions not allowing outpatient management (severe comorbidities, social condition…) in addition to the sPESI score, the HESTIA rule significantly overtook the sPESI, with respectively 45.7% [36.5-55.2] and 26.7% [19.1-35.8], p = 0.004. Of note, the number of discordant results (suitable or not for outpatient management) between the two rules was 33.3% [25.1-42.8]. These conclusions were unchanged using the original version of the PESI.

Conclusion: sPESI score or HESTIA rule both identify a relevant proportion of PE patients suitable for outpatient care, but with a high level of discordance between the two rules. The HESTIA rule may select a higher proportion of patients when considering medical conditions requiring inpatient management despite a low-risk of death according to sPESI.


Thomas MOUMNEH (Tours), Julie LECHEVAILLIER, Delphine DOUILLET, Pierre-Marie ROY
11:00 - 11:05 #11666 - Cbrn preparedness of Dutch ambulance teams: the impact of research.
Cbrn preparedness of Dutch ambulance teams: the impact of research.

Introduction: The Netherlands is a densely populated country in Northern Europe. With several nuclear installations, a heavy petrochemical industry, transport of related products by road, rail or water and possible terrorist targets, the risk for CBRN incidents is eminent. In case of such an incident, ambulance personnel will be first to be confronted with victims but are they really prepared?  The Dutch Ambulance Academy shared this concern and organised an introductory day course on working in CBRN circumstances as pilot project in cooperation with the Defence CBRN Centre. A previous study revealed the gaps in preparedness. The course enhanced the scores of the participants but the practical knowledge however seemed to remain limited. Following this conclusions a 2-day course was designed with emphasis on practical training.

Material and methods: Participants of this new course completed an online survey on demographics, perceived knowledge, capability, willingness to work and training.  The reported answers were controlled with a set of theoretical/practical questions on the subject. Scores were compared with those of the pilot course and untrained ambulance personnel.

Results: Preliminary results reveal a mean age of 49 years, 44% has had any disaster training before. Eighty per cent works in the vicinity of a chemical risk installation and 20% near a nuclear installation. There was a higher estimated knowledge, ranging from 4.8/10 (vs. 2.9 in the untrained group and 3.6 in the pilot group) for nuclear incidents to 5.53/10 (vs. 4.46 and 4.59) in chemical incidents. Self estimated capability to deal with these incidents also scored higher, from 3.93/10 (vs. 2.28 and 3.59) in nuclear incidents to 4.67/10 (vs. 4.06 and 4.63) in chemical incidents. Up to 100% stated to be practically trained to use personal protective equipment (vs. 24 and 26%) with a clearly higher score on self estimated practical knowledge on this subject (7.53/10 vs. 3.35 and  4.22). A good practical training in decontamination was reported in 93.33% (vs. 27% and 43%) with also a higher score on practical knowledge (6.87/10 vs. 3.22 and 4.48).  The end score on the theoretical/practical test was also higher in the study group (7.47/10 vs. 4.65 and 5.98).  There was however no higher willingness to work, nor in nuclear nor in chemical incidents.

Conclusion: The preliminary data of this study illustrate how research has an impact on the evolution in training and enhances CBRN preparedness of Dutch ambulance teams. Further evaluation of participants of following training sessions seems mandatory.


Luc MORTELMANS (Antwerp, Belgium), Greet DIELTIENS, Marc SABBE
E-Poster Area

"Tuesday 26 September"

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PH4 - S2
10:45 - 11:05

E-Poster Highlight Session 4 - Screen 2

10:45 - 10:50 #11069 - Impact of a stroke information campaign on the number of emergency medical services calls between September 2014 and October 2015, in the Rhône area, France.
Impact of a stroke information campaign on the number of emergency medical services calls between September 2014 and October 2015, in the Rhône area, France.

BACKGROUND :

Approximately 150,000 strokes occur each year in France, but only 5 to 10% of patients have access to thrombolysis, mainly due to poor knowledge of stroke symptoms by the population. The main objective of our study was to evaluate the impact of a local information campaign on emergency medical services (EMS) call, for suspected stroke, in the Rhône area between September 2014 and October 2015, compared to a control area.

METHODS :

We carried out a controlled before and after study on 3 time-periods of 2 months to evaluate a multifaceted stroke awareness program deployed in the Rhône area (France), from October to December 2014. Key messages of the campaign were the recognition of stroke warning signs and the need to call EMS urgently, using multiple information media. We analysed all the calls to EMS for stroke suspicion, using databases of emergency health centers in the Rhône area and control area. To determine the impact of the campaign, we assessed the evolution of the number of EMS calls for stroke suspicions before the launch of the campaign (T0), at 3 months (T1) and 12 months (T2), compared to control area. We also studied the impact on the time between onset of symptoms and EMS calls and on the evolution of thrombolysis number.

RESULTS & DISCUSSION :

During these periods, we studied 707 calls (214 at T0, 234 at T1 and 259 at T2) to EMS in the Rhône area for stroke suspicion, compared with 519 (186 at T0, 174 at T1 and 159 at T2) in the control area. We found a 21% significant increase of EMS calls in the intervention area over the period studied (p <0.05). No significant effect was found on the secondary criteria.

CONCLUSION :

Our information campaign had an impact on the population, improving EMS call, but it remains limited and to be confirmed by other studies. The goal will be to develop better information campaign to improve access to reperfusion strategies.


Caroline LAUDE (LYON), Anne TERMOZ, François LOIZZO, Norbert NIGHOGHOSSIAN, Anne Marie SCHOTT, Julie HAESEBAERT
10:50 - 10:55 #11235 - Effect of low doses of ketamine in nephritic colic.
Effect of low doses of ketamine in nephritic colic.

Background:
Renal colic is a frequent reason for consultation in emergency department (ED). Its adequate analgesic treatment remains a preoccupation of the clinician. The aim of our study is to evaluate the tolerability and efficiency of the association of low doses of ketamine with morphine in the management of renal colic in ED.

Methods:

Prospective, randomized, double-blind study conducted at the ED in university hospital over a six-month period, including 62 patients admitted for renal colic with numerical pain rating scale (NRS)>5, randomized into three groups: standard group: receiving morphine 0.1mg / kg associated with placebo, group1: receiving morphine 0.1mg / kg associated with 0.15mg / kg ketamine and group 2: receiving morphine 0.1mg / kg associated with 0.3 Mg / kg ketamine.

Results:The demographic characteristics were comparable for the three groups with an average age at 38 ± 12 years, a sex ratio at 1.13.   51.6% of the patients didn't have previous diseases and 27.4% were known carriers of renal lithiasis. 53.2% of patients used analgesics prior to initiation of the protocol. The three groups were also clinically comparable with an initial mean NRS of 9.4. A significant decrease in NRS within 30mn is observed in the ketamine0.3 group compared to the other two groups (p= 0.01).  The analgesic effect, judged by the SPID, was better in group 2 compared to the 2 other groups with p <0.05.  The total dose of morphine consumed decreased significantly in the two ketamine groups with an average of 9.59 mg for group 1 and 7.55 mg for group 2 compared to the standard group which showed an average of 11.95 mg with p <0.01. Total patient satisfaction assessed via TOTPAR was better in group 1 compared to placebo (p = 0.22) and in group 2 compared to group 1 (p = 0.013) in group 2 compared to placebo (p < 0.01). Ketamine was globally well tolerated. There was no statistically significant difference in adverse events among the three groups (p = 0.806) with predominance of gastrointestinal adverse events in the placebo morphine group (p = 0.01) and neuropsychic adverse effects in the 2 ketamine groups compared to the morphine group alone (p = 0.04).

Discussion:The association of low doses of ketamine (at a dose of 0.3 mg / kg) to morphine is well tolerated and allowed a better analgesia, with greater patient satisfaction compared to morphine alone in patients suffering from nephritic colic.


Khaoula RAMMEH, Hajer KRAIEM (Sousse, Tunisia), Dorsaf ADALA, Majdi OMRI, Mariem KHROUF, Mehdi METHAMEM
10:55 - 11:00 #11441 - Unexpected situations in a medical dispatch center: added-value of a training session.
Unexpected situations in a medical dispatch center: added-value of a training session.

Introduction

Managing unexpected situations such as mass casualties, disaster relief, and failure of dispatch software or equipment breakdown requires specific knowledge from both Emergency Medical Dispatcher (EMD) and dispatching physicians.

Both EMDs and physicians handle all incoming medical emergency calls in France and they need to work in close cooperation. Training sessions were performed in a pre-hospital emergency medical service for all professionals working at a dispatch center in order to reinforce this teamwork in unexpected situations. These half-day sessions consisted in different scenarios split in 2 situations: 1) mass casualty events (flood, building fire and mass shooting); 2) technical breakdown (computer aided dispatch system breakdown). Each session was composed of 2-persons teams: 3 EMDs working in partnership with 3 physicians. Each training session started with an evaluation of knowledge followed by evaluation after training.

The objective of this survey was to evaluate the added value of a training session that concerned unexpected situations in a medical dispatch center.

Method

5 training sessions from May 2016 to February 2017 were organized. 24 people (10 EMD and 14 physicians) answered a 26-item questionnaire that included 9 technical questions and 16 mass casualties’ questions before the training session and immediately after training. They answered to each assertion as true, false or did not know. A mark of 1 was assigned for each correct answer. Age, gender and seniority in the profession were also collected.

Analyses were presented as means and percentages. Each 26-item score was analyzed as a score, with 2 sub-scores concerning technical breakdown and mass casualty. Comparisons were performed with Ttests.

Results

2/3 of participants were female. 46% were younger than 40 years old and 12% older than 50 years old. 79% of them did work 5 years or less in a dispatch center.

Mean global scores were 11.66 (4.67 Standard Deviation – SD) out of 26 before the evaluation and 19.83 after the evaluation (SD: 3.34) (p<10-3). The mean scores for mass casualty were 7.42 (SD: 3.10) out of 16 at first evaluation and 12.83 (SD: 1.90) after the session. The mean scores for technical breakdown were 4.13 (SD: 2.66) out of 9 at first evaluation and 6.54 (SD: 1.44) after the session. There were no differences in scores when comparing EMDs and physicians, but there were significant differences in the scores between first and second evaluation.

Discussion

These training sessions were very positive, with significant improvement of scores after the half-day sessions. Organizing training sessions for all professionals working in a dispatch center is essential, specifically concerning events that happen very rarely. Teamwork brought cohesion, which is critical in the first minutes of such unexpected events.


Isabelle LAFFRAT (GARCHES), Jérémie BOUTET, Cecile URSAT, Céline FENIOUX, Jonathan FOURNÉE, Mathias HUITOREL, Céline VINTEZOU, Anna OZGULER, Michel BAER, Thomas LOEB
11:00 - 11:05 #11539 - Nine years (2008-2017) in-hospital Basic Life Support Training for all nurses: We keep going!
Nine years (2008-2017) in-hospital Basic Life Support Training for all nurses: We keep going!

Objective

The first 2 links in the “Chain of survival”, and thus cardiopulmonary resuscitation training, are mandatory for a good patient outcome. Poor knowledge and skill retention following resuscitation training has been documented over the past 25 years.

We developed a basic life support training program for clinical nurses and we composed a six-stage plan based on the ERC algorithm for in-hospital resuscitation.

We defined two quality standards (which we had to modify, as the guidelines changed in 2010) to measure if there was an improvement in the resuscitation skills after four sessions.

Methods

The whole nursing staff (ca. 400 individuals) in our hospital had to register for a fourth obligatory basic life support session, with the consent of the Board of Directors.

The performance of the nurses was recorded on an Ambuman manikin (with Ambu CPR software version 2.3.9), lying in a hospital bed.

Several variables were recorded, e.a. the correct execution of the sequence of the six-stage-plan, the compression rate, the compression depth and the ventilation volume. Using two quality ‘standards’, we compared the results session.

Results

The attendance to those sessions is significantly lower when the nursing staff had to enrole themselves.

For the first two sessions (2005 guidelines), we saw a compression depth between 40mm and 50mm was achieved by 120 or 37% (vs 95 or 31% in first session) (p=0,09) (fig. 2); a compression rate between 80/min and 120/min was achieved by 254 or 79% (vs 221 or 72% in first session) (p=0,03) (fig. 3); a ventilation volume between 400ml and 700ml was achieved by 148 or 46% (vs 97 or 31% in first session) (p<0,001) (fig. 4).

Optimal resuscitation (defined as a combination of those three determinants) was achieved by 44 or 14% (vs 25 or 8% in first session) (p=0,03). Satisfying resuscitation (defined as a combination of a compression rate between 70/min and 130/min, a compression depth more than 35mm and a ventilation volume more than 300ml) was achieved by 228 or 71% (vs 98 or 32% in first session) (p<0,001) (fig 5.)

For the third, fourth, fifth, sixth, seventh and eighth session, we defined  optimal resuscitation as a compression depth >50mm, compression rate 100-120/min and ventilation volume between 400ml and 700ml. We defined satisfying resuscitation as a compression depth >45mm, compression rate 90-130/min and a ventilation volume more than 300ml. The 2017 session showed that 73% achieved a satisfying compression depth, 96% achieved a satisfying compression rate and 96% achieved a satisfying ventilation volume. This is, so far, our best result in 9 years.

Using Fisher exact test, we found a significant improvement (p<0,001) for ventilation volume and for satisfying resuscitation.

 

Conclusion & perspectives

We need to thank the team of BLS instructors for their efforts to keep the resuscitation knowledge of the whole nursing staff at this level. We will continue to support this project on director’s level.


Thierry SCHISSLER, Fien DEWULF (jabbeke, Belgium), Dr Bart LESAFFRE
E-Poster Area

"Tuesday 26 September"

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PH4 - S3
10:45 - 11:05

E-Poster Highlight Session 4 - Screen 3

10:45 - 10:50 #11135 - Out-of-hospital cardiac arrest and pregnancy: observational study.
Out-of-hospital cardiac arrest and pregnancy: observational study.

Introduction: There is very little data in scientific literature regarding out-of-hospital cardiac arrest (OHCA) in pregnant women. This study aims to describe a group of pregnant women who experienced an OHCA and were treated by a pre-hospital Advanced Life Support (ALS) team, and to report the short-term outcome.

Materials and Methods: Retrospective observational study. Approval of the Ethics Committee. Inclusion criteria: pregnant woman > 18 years of age experiencing an OHCA, regardless of the stage of the pregnancy, treated by an ALS Team. Collected variables: age, term of pregnancy (weeks of gestation), location, presence of a witness, first documented rhythm, number of external electric shocks (EES) administered by an automatic external defibrillator (AED), use of an automated chest compression device (ACD), administration of drugs, and outcome (dead in the field, transport to hospital). Statistics: qualitative variables were expressed as a percentage, quantitative variables as a median [interquartile range, IQR]. The description was univariate.

Results: Over a period of 5 years, among 19,515 OHCAs, 17 concerned pregnant women. These 17 (100%) patients had a median age of 31 years (IQR [28-34]) and a median term of 20 weeks of gestation (IQR [9-32]) (6 missing data). Three (18%) OHCAs occurred in a public area and 14 (82%) took place at home. A witness was present in 12 (70%) cases, of which 6 bystanders initiated chest compressions (CC). The no-flow median time was 4.5 min (IQR [1-9]) and the low-flow median time was 42 min (IQR [30-70]). The cause of the OHCA was identified in 11 cases/17: 4 injuries (2 stab wounds, 1 hanging, 1 defenestration) and 7 medical causes (3 pulmonary embolisms, 2 myocardial infarctions, 1 hypoxia, 1 hypertrophic cardiomyopathy). Two patients (12%) received an EES by the first aid worker’s AED. Nine (53%) benefited from ACD. The median quantity of adrenaline injected was 10 mg (IQR [5-15]). One patient underwent thrombolysis and 6 were transported alive to hospital. Two patients were alive on day 30 following the OHCA.

Discussion : This is the first series of cases documented in medical literature. The diverse causes of OHCA were most often not related to the pregnancy. The rate of Ventricular Fibrillation was lower than for the general population. Of the 3 OHCA≥20 weeks of gestation, none survived. The recommendations for the treatment of OHCA in pregnant women are currently not applicable to the pre-hospital setting and are the subject of local consensus meetings aimed at producing a protocol adapted to these specific pre-hospital situations.

 


Olga MAURIN (Marseille), Sabine LEMOINE, Daniel JOST, Olivier YAVARI, Clément DERKENNE, Michel BIGNAND, Jean-Pierre TOURTIER
10:50 - 10:55 #11256 - Acute Decompensated Heart Failure - Are we failing?
Acute Decompensated Heart Failure - Are we failing?

INTRODUCTION

Acute Dyspnoea is a common presenting complaint to the Emergency Department (ED). Studies have shown that acute decompensated heart failure (ADHF) is difficult to diagnose with standard modalities in the ED. The primary objective of this study is to estimate the accuracy of ADHF diagnosis in two Irish tertiary EDs.

METHODS

This is a retrospective multi-center study conducted in two tertiary university hospitals in Dublin. All patients who were discharged from the hospitals between 1st January 2016 to 30th June 2016 with a HIPE diagnosis of ADHF were included.

RESULTS

280 patients were found in the HIPE search. 61 elective patients were excluded leaving a total of 219 study patients. Of these, 95 (43.4%) were accurately diagnosed with ADHF by the Emergency Physician.  Of those who were not diagnosed in the ED (n=124, 56.6%) . 65 (52.4%) had a CXR which was normal or suggested an alternative pathology compared to 21 (22.1%) p<0.0001 in the accurate group. In the missed group, 57 (46%) had no previous history of CCF compared to the accurate group 43 (45.3%). Length of stay for the missed group was 13.2 days compared to 13.6 days (p=0.896) for the accurate group. Time to X-ray for both groups 

CONCLUSION 

With the currently available diagnostic strategies, our study suggests that the diagnosis of ADHF is difficult in the ED. Recent studies suggest that basic bedside lung ultrasound would improve the early diagnosis of ADHF by emergency physicians.


Dr Nicolas LIM (Singapore, Singapore), Arthur HENNESSY, Andrew PATTON, Geraldine MCMAHON, John CRONIN
10:55 - 11:00 #11350 - Similar clinical performance of a novel point-of-care cardiac troponin assay with central laboratory high-sensitivity cardiac troponin I testing for diagnosis of acute myocardial infarction.
Similar clinical performance of a novel point-of-care cardiac troponin assay with central laboratory high-sensitivity cardiac troponin I testing for diagnosis of acute myocardial infarction.

Rapid diagnosis of acute myocardial infarction (AMI) facilitates early disposition of chest pain patients presenting to the emergency department (ED). Point-of-care (POC) cardiac troponin testing may improve patient throughput but is currently discussed due to limited diagnostic accuracy. We compared the diagnostic accuracy of a novel cTnI test (Minicare cTnI, Philips), with a currently available POC cTnI (i-Stat cTnI, Abbott) and high-sensitivity central laboratory cTnI assay (Architect Stat High Sensitive Troponin-I assay, Abbott).

Methods: The clinical performances of these assays were compared in samples from 450 patients from an adjudicated outcome of AMI. The blood samples were drawn on ED admission and 3 h later. Bassink-Bablok regression analysis was used for comparisons between assays.

Results: Minicare cTnI correlated with Architect hs-cTnI (r2=0.85, p<0.0001) and I-Stat cTnI (r2=0.93, p<0.0001). Areas under the receiver operating characteristics curves were 0.87-0.91 at admission (p=ns) and 0.96-0.97 3h after admission (p=ns). The negative predictive value (NPV) at admission were 95% (92-97%, 95% CI) for Minicare cTnI and increased to 99% (97-100%) at follow-up testing, and were comparable to Architect hs-cTnI (98%, 96-100%), but higher than I-Stat cTnI (95%, 92-97%; p<0.01). Negative likelihood ratios (LR-) after 2-4h were 0.06 (0.02-0.17, 95% CI) for Minicare cTnI, 0.11 (0.05-0.24) for Architect hs-cTnI (p=0.02) and 0.28 (0.18-0.43) for I-Stat cTnI (p<0.0001). The clinical concordances between Minicare cTnI and Architect hs-cTnI were 92% (admission) and 95% (2-4h), with lower concordances among Minicare cTnI and i-Stat cTnI testing (83% and 78%, respectively; p=0.007).

Conclusion: The Minicare cTnI POC assay tested on fresh whole blood samples demonstrated similar clinical performances to a current, high-sensitivite cTnI assay fort he diagnosis of AMI 3h after presentation. Minicare cTnI POC assay may be useful to aid in ruling-out of AMI in ED patients with suspicion of acute coronary syndrome using a guideline supported 0/3h testing protocol.


Christ MICHAEL (Lucerne, Switzerland), Per VENGE, Van Lippen LIAN, Blaschke SABINE, Geier FELICITAS, Giannitsis EVANGELOS, Emil HAGSTRÖM, Pierre HAUSFATER, Khellaf MEHDI, Johannes MAIR, David PARIENTE, Volkher SCHARNHORST, Veronique SEMJONOW
11:00 - 11:05 #11599 - Optimizing the ISAR-HP to screen efficiently for functional decline in older patients.
Optimizing the ISAR-HP to screen efficiently for functional decline in older patients.

Introduction: The Identification of Seniors At Risk-Hospitalized Patients (ISAR-HP) has recently been included in guidelines as a frailty indicator to identify patients for comprehensive geriatric assessment. Previous studies showed that the conventional cut-off score classifies a high percentage of patients as high risk incorrectly. We aimed to optimize the predictive value of ISAR-HP by using different cut-offs in older acutely hospitalized patients.

Methods: A prospective follow-up study was performed in two Dutch hospitals. Acutely hospitalized patients aged ≥70 years were included. Demographics, illness severity parameters, geriatric measurements and the ISAR-HP scores were obtained at baseline. The primary outcome was a combined end point of functional decline or mortality during ninety day follow-up.

Results: In total 861 acutely hospitalized older patients were included, with a median age of 79 years, of whom 276 (36.1%) experienced functional decline or mortality. The conventional ISAR-HP cut-off of ≥2 assigned 432/765 patients (56.5%) as high risk, with a positive predictive value (PPV) of 0.49 (95%CI 0.45-0.54) and a negative predictive value of 0.81 (95%CI 0.76-0.85). Thus, 51% of those whom the ISAR-HP denoted as high risk did not experience the outcome of interest.  Raising the cut-off to ≥4 assigned 205/765 patients (26.8%) as high risk, with a marginally increased PPV to 0.55 (95%CI 0.48-0.62).

Conclusion: The ISAR-HP with the conventional cut-off of ≥2 incorrectly identifies a large group of  patients at high risk for functional decline or mortality and raising the cut-off to 4 only marginally improved performance. Caution is warranted to ensure efficient screening and follow-up interventions. 


J. DE GELDER, J.a. LUCKE (Haarlem, The Netherlands), L.c. BLOMAARD, E HAENEN, R.a.j. SMIT, H.g. KLOP, K. MESRI, B. DE GROOT, A.j. FOGTELOO, S ANTEN, G.j. BLAUW, S.p. MOOIJAART
E-Poster Area

"Tuesday 26 September"

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PH4 - S5
10:45 - 11:05

E-Poster Highlight Session 4 - Screen 5

10:45 - 10:50 #10841 - How often does troponin elevation identify acute myocardial infarction in the Emergency Department in the United States?
How often does troponin elevation identify acute myocardial infarction in the Emergency Department in the United States?

Background: Cardiac troponin I (cTnI) is widely measured in Emergency Department (ED) patients (up to14% of all) having any suspicion of possible Acute Myocardial Infarction (AMI). However cTnI can be elevated in a multitude of clinical scenarios other than the thrombotic occlusion of a coronary artery, such as tachycardia, heart failure, sepsis, pulmonary embolism, renal failure, stroke and others. The objective of this study was to determine how often elevated cTnI, at various levels, is associated with a final diagnosis of AMI.

Methods: Adult ED patients being evaluated for possible AMI were prospectively enrolled (from May, 2013 through April 2015) in a single urban center study in the United States (US). Exclusion criteria included acute trauma, distress requiring immediate life-saving intervention, cardioversion or defibrillation or receiving thrombolytic therapy within 24 hours, STEMI requiring immediate reperfusion, pregnancy or breast feeding, and if previously enrolled in the study. Serial cTnI (Siemens Ultra cTnI) measurements were obtained with values > 0.04 ng/ml (99th %) considered to be elevated. The diagnosis of AMI was adjudicated by a cardiologist and an emergency medicine physician (with a 3rd cardiologist available if there was diagnosis disagreement) in accordance with the 3rd universal definition of AMI using all available clinical information obtained over the 30 days after the ED visit. The highest individual patient cTnI was utilized for the analysis and the cTnI values were divided into interquartile ranges.

Results: Of the 569 patients enrolled 116 (20.4 %) had at least one cTnI > 0.04 ng/ml. Of these 72 (62.1%) had a non-AMI diagnosis while 44 (37.9 %) had a final AMI diagnosis. Baseline characteristics of these 2 groups showed no significant differences with the exception of higher medical history of prior revascularization, congestive heart failure and emphysema in those with AMI. Patients with lower cTnI levels (0.05-0.06 ng/ml) were unlikely to have AMI and the incidence of AMI increased with higher cTnI values (p< 0.001). The highest individual patient cTnI values were divided into interquartile ranges. The number of individuals in each quartile with AMI were: 0.05-0.06; 1 AMI (2.3%), 28 non-AMI; 0.07-0.10; 7 AMI (15.9%), 21 non-AMI: 0.11-0.67; 12 AMI (27.3%), 18 non-AMI:  and >0.68 ng/ml; 24 AMI (54.5%), 5 non-AMI. There were very few 30-day deaths (4/569, 0.7%) out of which 3 were non-cardiac in etiology.

Conclusions: cTnI is a highly sensitive biomarker aiding in the detection of myocardial cell damage. However, the majority (62.1%) of ED patients being evaluated for possible AMI and having at least one elevated cTnI (> 99th %) value did not have a final AMI diagnosis. However the incidence of adjudicated AMI diagnosis significantly increased with higher cTnI interquartile ranges. This trend will likely increase in the US with the current introduction of high sensitivity cardiac troponin assays.

 


Richard NOWAK (Detroit, USA), Tarun JAIN, Michele MOYER, Michael HUDSON, Gordon JACOBSEN, James MCCORD
10:50 - 10:55 #11091 - Patterns of ultrasound diaphragm function in infants with bronchiolitis: a prospective study.
Patterns of ultrasound diaphragm function in infants with bronchiolitis: a prospective study.

BACKGROUND

Ultrasonography allows direct observation of the diaphragm. Its thickness variation has been recently used to assess work of breathing in ventilated patients. In children, only one study describing diaphragm ultrasound findings in healthy children have been performed. We aimed to assess the diaphragmatic function in infants with bronchiolitis.

 

METHODS:

Prospective study of infants with bronchiolitis (first episode, aged 1-12 months) evaluated in a tertiary level pediatric emergency room. Infants with life threatening disease requiring immediate intervention, preterms, infants with with cardiac diseases or comorbidities or genetical disorders or disability were excluded. Diaphragm thickness was measured in the zone of apposition and the thickening fraction (TF) was calculated as (thickness at inspiration - thickness at expiration)/thickness at expiration per 100 (therefore expressed as percentage); the higher the values, the higher the respiratory effort of the child, while values ≤ 20% indicated diaphragm dysfunction. Diaphragm excursion (DE), Ti/Ttot (time of inspiration divided by total respiratory act time – the lower the value the longer the expiration time)  were calculated.

 

RESULTS:

61 infants were enrolled (mean age 83 days, IQR 60.5 – 180, males 50.1%). Bronchiolitis score was mild in 43.1%, moderate in 48.3%, severe in 8.6% cases. 19.7 % children were discharged, 80.3 % were admitted for a median length of 4 days (IQR 2-6.5). Respiratory Syncitial Virus was the most common etiological agent (47.4% cases). 27 children required no oxygen delivery, HFNC were started in 25 cases, among these 7 required CPAP, of these 2 required mechanical ventilation.

Mean TF was 47% (IQR 28.6-64.7), mean Ti/Ttot was 0.47 (± 0.15), mean DE was 10.39 mm (± 4)

Infants with severe bronchiolitis had lower TF than moderate (P 0.03), indicating diaphragm dysfunction, while those with moderate bronchiolitis showed the highest respiratory effort (highest TF). All children with lower values of TF required HFNC and one of them required CPAP. There was a linear correlation between TF and oxygen saturation (P 0.013).

Children with severe bronchiolitis had higher DE and lower Ti/Ttot compared with those with mild bronchiolitis, even though statistically significant differences were not reached probably due to low numbers of patients evaluated.

The higher the eco score the higher DE (P < 0.05).

These parameters did not significantly correlate with length of admission and type of respiratory support, while correlated with length of HFNC support.

 

CONCLUSIONS:

For the first time to our knowledge, this study provides reference values for DE, TF and Ti/Ttot in otherwise healthy infants with bronchiolitis. TF seems a promising parameter to predict those infants that might require respiratory support. Further studies are needed to understand which one of these parameters may predict need of respiratory support and admission.


Danilo BUONSENSO, Maria Chiara SUPINO, Antonino REALE, Emanuele GIGLIONI, Massimo BATTAGLIA, Simona SCATENI, Alessia MESTURINO, Barbara SCIALANGA, Nicola PIROZZI, Anna Maria Caterina MUSOLINO (rome, Italy)
10:55 - 11:00 #11623 - The Diagnostic Value of Novamed’s Sens-a-Heart Rapid Assay in Patients with Definite and Possible ACS.
The Diagnostic Value of Novamed’s Sens-a-Heart Rapid Assay in Patients with Definite and Possible ACS.

Background:

Sensitivity, specificity, and precision of the various commercially available troponin assays vary considerably. Sens-a-Heart is a novel rapid test using a combination of biomarkers, which provides a yes/no answer within 15 minutes using a single droplet of blood.

 

Aims:

The purpose of this study was to evaluate diagnostic accuracy of rapid Sens-a-Heart testing in patients with definite or possible ACS.

 

Methods:

The Sens-a-Heart test was performed in 191consecutive pts with definite or possible ACS admitted to departments of Hadassah Medical Center (Jerusalem) from 01.09.2015 till 31.03.2017. Initial troponin evaluation and simultaneous Sens-a-Heart testing were done under the ESC and ACC consensus guidelines.

 

Results:

Final diagnosis of ACS was established in 124 (65%), nonischemic heart disease documented in 3 (1.5%) and noncardiac disease in 64 (33.5%) of patients.

 

The Sens-a-Heart test was highly sensitive to coronary events. (77% of cases vs standard Hadassah troponin test which revealed 67% of cases).

 

The Sens-a-Heart test is also has high specificity for ACS. (96% vs 94% in Hadassah troponin test). Upon combining of both test results a higher sensitivity is achieved (86% sensitivity with specificity of 90%).

 

Table 1.

 

Roche ultra-sensitive troponin T test (Hadassah)

Sens-a-Heart Rapid Assay (Novamed)

Combined results (Sens-a-Heart + Hadassah’s Troponin)

Sensitivity

67%

77%

86%

Specificity

94%

96%

90%

 

 

Roche ultra-sensitive troponin T test (Hadassah)

Sens-a-Heart Rapid Assay (Novamed)

Combined results (Sens-a-Heart + Hadassah’s Troponin)

Sensitivity

67%

77%

86%

Specificity

94%

96%

90%

 

Conclusion: Novamed’s Sens-a-Heart Rapid Assay has prominent diagnostic sensitivity and specificity in patients with ACS in a very short time.

 


Ahmad NAMA (Jerusalem, Israel)
11:00 - 11:05 #11665 - Quick SOFA scores predict mortality in adult emergency department patients with and without suspected infection.
Quick SOFA scores predict mortality in adult emergency department patients with and without suspected infection.

Introduction :

The quick sequential Organ Failure Assessment scores (q SOFA) may identify patients with infection who are at risk of complications .We determined the correlation between q SOFA scores and mortality in adult emergency department (ED) patients with and without infection.

Methods:

We performed a prospective and descriptive study of all adult patients admitted to the ED between February 2017 to March 2017. We calculated the qSOFA for all patients on admission .We study the correlation between q SOFA scores and inpatient mortality (intra hospital and 2 weeks mortality )

Results:

We included 153 patients. Mean age was 60±7 years old. 34 % were female and 66% were male. Hypertension and diabetes are the frequent associated disease (46, 2% and 37, 8% respectively) Different diagnosis are defined, the most frequent are coronary disease (35 %) and pneumonia (27%).  Septic patients are representing 43 % of patients .We studied the correlation between q SOFA scores and mortality. We find that when the q SOFA is less than 2 we have 1, 6% of mortality. and  when the q SOFA more than 2 the  mortality rate is  13% .We concluded a significant positive correlation between the Q sofa score and 2 weeks mortality ( p=0.04)

Conclusion:

QSOFA scores were associated with inpatient mortality, in adult ED patients likely to be admitted both with and without suspected infection and may be useful in predicting outcomes.


Houda NASRI (CHARTRES), Olfa DJEBBI, Rim HAMAMI, Yosra GUETARI, Dkhera HAMDI, Saloua MANSOURI, Khaled LAMINE
E-Poster Area
11:10

"Tuesday 26 September"

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A32
11:10 - 12:40

Cardiovascular (Cutting Edge)

Moderators: Barbra BACKUS (Emergency Physician) (Rotterdam, The Netherlands), Szabolcs GAAL (Deputy head) (Budapest, Hungary)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
11:10 - 11:40 What is the future of chest pain assessment? Moving beyond single biomarkers and dichotomous test results. Martin THAN (Speaker, New Zealand)
11:40 - 12:10 Make Endocarditis Great Again. Dr David CARR (Associate Professor of Emergency Medicine) (Speaker, Toronto Canada, Canada)
12:10 - 12:40 Management of Recent-onset Atrial Fibrillation and Flutter (RAFF): Time for the ED to take Control. Ian STIELL (Physician) (Speaker, Ottawa, Canada)
Trianti Hall

"Tuesday 26 September"

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B32
11:10 - 12:40

SonoOlympics-Ultrasound in the cradle of civilization
The ultimative and interactive ultrasound competition

Moderators: James CONNOLLY (Consultant) (Newcastle-Upon-Tyne), Riccardo LETO (Emergency physician) (Genk, Belgium), Senad TABAKOVIC (Medical director emergency department) (Zürich, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
Keynote Speaker: Hein LAMPRECHT (Keynote Speaker, South Africa)
Mitropoulos

"Tuesday 26 September"

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C32
11:10 - 12:40

Neurological (How To)

Moderators: Vassilios GROSSOMANIDES (Greece), Christian HOHENSTEIN (PHYSICIAN) (BAD BERKA, Germany)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
11:10 - 11:40 Stroke. Carsten KLINGNER (Speaker, Germany)
11:40 - 12:10 SAH. Jeff PERRY (Physician) (Speaker, Ottawa, Canada)
12:10 - 12:40 Damned If you do, damned If you don’t – Malpractice in stroke care. Greg HENRY (Speaker, USA)
Banqueting Hall

"Tuesday 26 September"

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D32
11:10 - 12:40

YEMD - WLB
Health & Wellbeing

Moderators: Alice HUTIN (PH) (Paris, France), Judith TINTINALLI (Professor) (Chapel Hill NC, USA)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
11:10 - 11:30 Sleep deprivation and physical issues in emergency physicians. Laura HOWARD (Speaker, United Kingdom)
11:30 - 11:50 Is Emergency Medicine a job good for a lifetime? Roberta PETRINO (Head of department) (Speaker, Italie, Italy)
11:50 - 12:10 How to make an ED attractive to young doctors. Judith TINTINALLI (Professor) (Speaker, Chapel Hill NC, USA)
12:10 - 12:30 Can we get over the sadness in Emergency Medicine? Tatjana RAJKOVIC (Speaker, NIS, Serbia)
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Nursing session 2
Detection of Family Maltreatment at the Emergency Department

Moderators: Thomas DREHER-HUMMEL (Nurse) (Basel, Switzerland), Door LAUWAERT (Manager) (BRUSSELS, Belgium)
11:10 - 11:30 Detection of child maltreatment: screening in the Emergency Departments. Henriette MOLL (paediatrician) (Speaker, rotterdam, The Netherlands)
11:30 - 11:50 A new successful method for detecting child maltreatment based on parental characteristics. Hester DIDERICH-LOLKES DE BEER (policy officer family maltreatment) (Speaker, THE HAGUE, The Netherlands)
11:50 - 12:10 Implementation with the help of mandated training and e-learning. Marielle DEKKER (Speaker, The Netherlands)
12:10 - 12:30 Detection of Elderly maltreatment. Sivera BERBEN (research coordinator) (Speaker, Nijmegen, The Netherlands)
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F32
11:10 - 12:40

Free Papers Session 9

Moderators: Anthony GERASKLIS (Greece), Felix LORANG (Consultant) (Erfurt, Germany)
11:10 - 11:20 #10724 - OP073 Management of Coronary Artery Disease in Emergency Phase: Experiences of Iranian Patients.
OP073 Management of Coronary Artery Disease in Emergency Phase: Experiences of Iranian Patients.

Background:

Coronary Artery Disease (CAD) is one of the major causes of death. Evidence suggests that some preventive measures by patients in emergency phase can reduce the rate and risk of mortality. Thus, understanding the signs and risk factors of CAD from the patients’ perspective and their ways of dealing with this disease is of vital importance.

Objectives: This qualitative study aimed to explore the Iranian patients’ experiences about CAD and how they manage it in their first encounter.

Patients and Methods: This study was a grounded theory study conducted on 18 patients with CAD. The data were collected through semi-structured interviews. Initially, purposeful sampling was performed followed by maximum variety. Sampling continued until data saturation. Then, all the interviews were recorded and transcribed verbatim. After all, the data were analyzed by constant comparative analysis using MAXQUDA2010 software.

Results:

The themes manifested in this phase of disease included 1- "Invasion of Disease"  with subthemes of "warning signs" and "risk factors", 2- "Patients’ Primary Challenges" with subthemes of "doubting primary diagnosis and treatment", and feeling of being different from others", 3- "Psychological Issues" with subthemes of "mental preoccupation", "fear of death and surgical intervention", "stress due to recurrence",  and "anxiety and depression", 4- "Management Strategies" with subthemes of "seeking for information", "follow-up' , and "control measures".

Conclusions: Based on the results, physicians and nurses should focus on empowerment of patients by facilitating this process as well as by educating them with regards to dealing with CAD. Further, it is also essential for the mass media to educate the public on how to treat patients with CAD.

Key words: Management, Coronary Artery Disease, Emergency Phase, Grounded theory, Iran 


Hossein KARIMI MOONAGHI (Mashhad, Islamic Republic of Iran), Mohammad MOJALLI
11:20 - 11:30 #10853 - OP074 Positive feedback with Human Factors - Does it matter in an Emergency Department ?
OP074 Positive feedback with Human Factors - Does it matter in an Emergency Department ?

Background: Our Emergency department at New Queen Elizabeth Hospital in Birmingham is one of the busiest Major Trauma Centres in UK with around 250 staff with annual attendances of more than 100,000 patients. The issues of work load, space, staffing level and performance makes it a challenging environment. A multidisciplinary teams are more likely to perform better if they are made to feel appreciated and their good practices are acknowledged. 

Learning from excellence is a new concept. The positive feedbacks are widely used in education for children and by corporate non- medical institutions. We wanted to explore its role in adult education and behaviour in the medical background. It’s very rare we recognise, celebrate and learn from good practice in the current working climate. The feedback had to timely, genuine, reflective, meaningful, specific and consistent. A template of a positive feedback along with specific local human factors framework (modification of NOTECHS II system) was developed based on the previous work on Favourable Event Reporting Form (FERF). The Human factors were analysed under the following topics- Leadership & management, Team building & cooperation, Problem solving and decision making, Situational awareness and environment. 

The new initiative of positive feedback forms were introduced to the entire medical, Nursing and managerial staff in the emergency department. We organised few educational sessions for all the staff. The project went live three months ago in January 2017. We chose the option of hard copies rather than the online version to capture more data.

Analysis and results: We had sixty positive feedback forms form last three months. The returned forms were reviewed and analysed by Non-Emergency department staff to minimise the bias. The common theme was that the staff felt more appreciated and acknowledged. The newly appointed staff felt more welcome and seemed to understand the expectation of their new working environment. Interestingly we also found that the staff would highlight the issues such as staff shortages and process on a feedback form. This has enabled the senior management to respond immediately to appoint more staff and emphasise/encourage on process to improve performance. It also shared the exemplary practice of certain staff highlighting their leadership skills, situational awareness and decision making process in a high pressure environment. The forms also were beneficial for all the staff as a part of their yearly appraisal. The staff felt supported during difficult times regardless of role or grade.A short staff survey is also planned following the implementation. The feedbacks are now a regular part of clinical governance structure .

In summary, the positive feedback forms are a valuable tool in adult education, behaviour and performance of a multidisciplinary team. The positive feedback reinforces good practice and encourages positive self- esteem among the various members of the team. 


Umesh SALANKE (Birmingham, United Kingdom), June SARGEANT, Tracey CLATWORTHY, Fran IVES
11:30 - 11:40 #10891 - OP075 Fast Track in the Emergency Department: an effective measure?
OP075 Fast Track in the Emergency Department: an effective measure?

Introduction: The increase in attendance of Emergency Department is responsible of a real problem of flow management. The implementation of a Fast Track (FT) is one of the organizational measures to improve this flow and thus to reduce the length of stay of daily patients. The aim of this study was to evaluate the effectiveness of implementation of a non-traumatologic FT (a trauma FT already existing) in our ED, and also to evaluate the staff’s satisfaction with the establishment of this procedure and the number of orientation errors.

Methods: We present here a prospective and observationnal study over a period of three months (winter 2015-2016) in an academic French ED. A total of 258 patients who received in FT were included in the study. This cohort was compared with a control group that consulted a year previously during the same period and who could have been eligible for care in the FT.

Results: Our study showed a significant reduction of ED length of stay of patients referred to FT (95.5 min for the FT group versus 141 min for the control group, p<0.0001) and a significant decrease in patients left without care by 6,1% (1.1% for FT group versus 2.8% for the control group, p=0.01). The rate of errors of orientation in patients initially referred to FT who had to be reoriented to the standard care system was 3,3% (95%CI: [3.2-3.4]). The implantation of this Fast Track was a measure deemed satisfactory by the paramedical ED teams with a score of 3.65 ±0.57 out of a total of 4 and in a more nuanced way by the medical teams with a satisfaction noted at 2.58 ±1.24 out of 4. In spite of the relative satisfaction of both paramedical and medical teams, our study also highlights the problem of ED utilization by patients with minor complaints.

Conclusion: Establishing a Fast Track in the ED could be one of the answer to reduce the length of stay of patients present with minor complaints. Organizational measures such as adequacy between the working hours of the FT and those of the physician responsible for it or the improvement of the computer tool (DxCare®) would make it possible to improve its functioning. The establishment of a FT was a satisfactory measure by paramedical and medical ED teams and significantly reduced the time taken to manage patients with non-urgent complaints.


Fanny SCHWEITZER, Claire KAM, Carmen HAMMANN, Céline RENFER, Sarah UGÉ (Strasbourg), Gabriella PINTEA, Pierrick LE BORGNE, Pascal BILBAULT
11:40 - 11:50 #11184 - OP076 Moderate to high complexity patients use the majority of resources in the emergency department - a modified TDABC analysis of ED utilization by RETTS category.
OP076 Moderate to high complexity patients use the majority of resources in the emergency department - a modified TDABC analysis of ED utilization by RETTS category.

Background Emergency department crowding and poor flow has been shown to lead to both poor clinical outcomes and poor patient experience.  As such, improving ED care is usually important to policymakers, but which visits should be highest priority to address is often controversial.  Many interventions to improve ED flow are focused on low-acuity, “fast-track” or primary care type patients, but it is not clear that these patients are the biggest drivers of ED crowding. Using a previously-developed Patient Encounter Costing (PEC) system, we show that simple triage level (RETTS in Sweden) can identify which patients drive ED utilization, and should be the key targets of improvement efforts.

Methods We used data from Region Halland, Sweden, a county of 300,000 people over 5,500 km2. We analyzed all 88,132 ED visits across 2 hospital-based ED sites in 2015.  These visits incurred total costs of 255 million Swedish Crowns (SEK), or approximately 26 million EUR. Time spent per visit was determined from prospectively recorded ED records, and resource adjusted by published weighting factors for nursing care by triage acuity level. We used PEC methods to determine unit-time costs for ED care, which were then used to determine total ED patient-care costs for each visit. These data were aggregated at the triage (RETTS) level, showing the variation by triage score.

Results In 2015, Region Halland spent 255 million SEK on its emergency departments, incurring unit costs of 1,645 SEK per nursing hour. This represents approximately 4% of total healthcare expenses in the region.  Patients were receiving care in a designated care space for a total of 262,705 hours.  The average ED visit service cost 2,886 SEK (95%CI 2,264-2,299). Average costs by RETTS level were: 650 SEK for triage level 5, 1 696 SEK for level 4, 2 824 SEK for level 3, 4 551 SEK for level 2, and 4 534 SEK for level 1.  In terms of total costs, 4% of total ED costs were spend on level 5 or uncoded visits, 9% on level 4, 47% on level 3, 34% on level 2, and 6% on level 1 patients.  ED treatment space utilization followed a similar pattern.

Conclusion 81% of ED costs, and 80% of total treatment-space utilization time, is spent on RETTS level 2 and 3 patients.  Interventions to improve ED throughput and resource utilization will be most effective if they focus on moderate to high-acuity and complexity patients, who often have multiple comorbidities and are at a higher risk of being admitted.  Low acuity and primary care oriented interventions are likely to have a more limited effect potential.


Zayed YASIN (Boston, USA), Jonathan SLUTZMAN, Magnus ROMELL, Jonas HULTGREN, Japneet KWATRA, Philip ANDERSON
11:50 - 12:00 #11270 - OP077 Nurse-led, physician-led or teamwork instead of triage: A longitudinal study of different triage processes and their impacts on patient flow at a busy emergency department.
OP077 Nurse-led, physician-led or teamwork instead of triage: A longitudinal study of different triage processes and their impacts on patient flow at a busy emergency department.

Objectives - To evaluate the impacts of two triage interventions compared to protocol-based comprehensive nurse-led triage on emergency department (ED) waiting times: senior physician-led triage and triage replaced by inter-professional teamwork in modules.

Design - A single center before-and-after study.

Setting – Conducted 2012.05.09 to 2015.11.11 at the adult ED of an urban county teaching hospital in Sweden, with 110 000 annual visits.

Participants – Registry data of patients arriving on weekdays 8 am to 9 pm during one year prior to the first intervention and one year immediately following each intervention.

Interventions - Senior physicians were reassigned to replace the triage nurses 8 am to 9 pm in the first intervention. In the second intervention, the triage section was abolished and replaced by inter-professional teamwork in modules.

Main outcome measures – Primary outcomes were the median total length-of-stay (LOS) and time to physician (TTP). Secondary outcome was the proportion of patients who left before treatment completed (LBTC).

Results – When senior physicians replaced the triage nurses, the median TTP plunged from 119 (95% CI; 117 to 120) to 57 min (95 % CI; 56 to 58). However, the median LOS increased from 236 (95% CI; 235 to 238) to 258 min (95 % CI; 256 to 260). When triage was abolished during teamwork in modules, the median LOS decreased to 229 min (95 % CI; 227 to 231). The median TTP was increased to 74 min (95 % CI; 73 to 76), yet 45 min shorter than during nurse-led triage. The LBTC rate increased over time: 2.5 % for nurse-led, 2.7 % for physician-led and 4.0 % for no triage during teamwork in modules. All differences in outcome measures were statistically significant with p-values < 0.001, except the non-significant difference in LBTC rate between nurse-led and physician-led triage.

Conclusions - Inter-professional teamwork in modules replacing triage performed the shortest LOS and may be an approach to cut waiting times in large busy EDs.


Jenny LIU (Stockholm, Sweden), Sari PONZER, Italo MASIELLO, Nasim FARROKHNIA
12:00 - 12:10 #11289 - OP078 "I am the Boss“ – Leading ad hoc teams in the shock room.
OP078 "I am the Boss“ – Leading ad hoc teams in the shock room.

Background

Teams in the shock room (SR) usually are so-called „ad hoc teams”: They randomly convene to fulfill an ambitious task under time pressure with limited information and usually leave the scene as soon as this task is completed. What are the essential requirements to lead such a team? What can help to reach excellence as team leader in the SR?

Methods

We searched in the medical literature for the expressions team leading / team leader / team coordinator and emergency medicine. Moreover we conducted a survey with experienced consultants in our Emergency Department, who regularly work as team leaders, asking them to tell us their challenges, but also tips and tricks for reaching high performance in the SR.

Results

Structure is often mentioned as important factor for high performance in the SR in the literature. This includes a briefing before the patient arrives, hands-off during handover, standards like the ABCDE and CRM (crisis research management) criteria or non-technical skills, and team debriefing after completion of the task. Additionally team resilience or high-performance teams can be found  in the literature as important factors for high-quality teamwork. These terms primarily stem from other highly dynamic industries outside of healthcare like nuclear power plants or aviation.

In interviews with experienced emergency physicians who regularly work as team leaders in the shock rooms, they stressed the importance of pre-existing structures and standards, which should be implemented by an experienced emergency physician as team leader. As examples the “ABCDE” and CRM principles are mentioned. Many of the emergency physicians expressed being challenged by their colleagues from anaesthesiology or surgery. “Risk factors” for losing the lead in the SR are being inexperienced, junior, short or female, having a low voice or the wrong position in the room. In order to clarify their role and responsibility, ED consultants mention good visibility by wearing a coloured jacket defining them as team leader, using a footstool, developing a strong voice or knowing the names and functions of all involved team members. They emphasize the importance of Interdisciplinary and interprofessional in-situ simulation training for developing standards of collaboration and shared mental models.

Discussion

Team leading in the shock room is extremely challenging: an ad-hoc team must collaborate in a highly dynamic situation with many uncertainties. Excellence as team leader not only depends on the team leader who must be highly competent in content, coordination and communication, but also on clear structures and standards. In order toe be prepared for often “unpreparable” situations, simulation training with all team members helps to reach excellence of care for patients whose survival often depends on high team performance.


Dr Monika BRODMANN MAEDER (Bern, Switzerland), Thomas SAUTER, Wolf HAUTZ, Aristomenis EXADAKTYLOS
12:10 - 12:20 #11968 - OP079 IMMIGRATION PROBLEM IN GREECE, Emergency Medical System Management.
OP079 IMMIGRATION PROBLEM IN GREECE, Emergency Medical System Management.

INTRODUCTION

Over 10,000 refugees lost their lives in the Mediterranean since 2016 in their endeavor to reach the European Union (EU), first half of 2016 there were 2809 deaths

Immigration, most important problem in the world today & a purely human challenge for all stakeholders, especially the EMS in GREECE, as national first responder.

The large flow of refugees into our country, through the Aegean islands, has created great challenges, in the field of health.

SCOPE-METHOD

In 2015, Greece, the main point of entry into the EU for refugees and immigrants from Turkey. It is estimated that 850,000 people attempted the dangerous passage of the Aegean Sea.

47,000 refs remained in Greece. Most of them (90%), originate from Syria, Iraq, Afghanistan. Among them people with severe health problems, pregnant women, infants.

The management of the severely ill amongst refugees based on a survival chain starting at the pre-hospital level, often at the site of arrival, and ends at the definitive care.

The role of EKAB, especially in the specific geographical relief of Greece, is particularly critical for the survival of people in distress.

Refugee-related diseases are unexpectedly severe, complex due to the difficulties of their situation: the extreme events of war; long-distance travel; lack of available medication for chronic pathologies; malnutrition; or the existence of past injuries. This vulnerable population, often consisting of infants and elderly, have reduced reserves in injury & sickness

CHARACTERISTICS

Children, 48% of the refugee population; men 30% & 22% women. 10% of refugees in Greece are 2 to 4 years old, 14% are aged between 5 and 9 years, 11% are aged 10 to 14 years old

MD in  small islands deal with an emergency patient among POPULATIONS ON THE MOVE in remote areas, in the absence of proper medical equipment in a small regional clinic on a border island and is able only to offer Initial stabilization and nothing  more. Afterwards the EKAB system ensures the transfer of the patient to a definitive care Centre.

 DATA

 Aeromedical Department of EKAB archives:

2016: Emergency Transfers by the Aeromedical Department numbered 46, involving newly arrived seriously-ill refugees. Of these 46 patients, 17 were infants with res/ry distress; another 7 were children (1.5 to 12 ys ) suffering from various infections, burns, choking, swallowing of foreign bodies. 72% male & 28% female. Syrians comprised 64% of the pts; Afghans 20%; Iraqis 12%; and Kurds, Iranians etc. Athens was the destination for 34 patients; 5 were sent to Crete; 7 to peripheral hospitals. AIRBORNE TRANSPORT was carried out in cooperation with the Greek Air Force C27 and C130 planes H/Ps: Chinook, Super Puma. The choice was based on geographic distances, availability of appropriate landing facilities, and local meteorological conditions.

The experience of air transport provides the opportunity for prompt intervention and better management of vulnerable patients involved in a mass migration event.


Jimi JIANNOUSI (ATHENS, Greece), Spyros PAPANIKOLAOU, Spiros DIMITROPOULOS, George PERDIKOGIANNIS, Dionysios KOUSKOUS
12:20 - 12:30 #10980 - OP080 Non-specific abdominal pain and readmissions in a high-volume emergency department.
OP080 Non-specific abdominal pain and readmissions in a high-volume emergency department.

Background

Acute abdominal pain is among the most common reasons for emergency department (ED) admissions. As abdominal symptoms are often vague, intermittent and non-specific, it may be difficult to distinguish non-specific conditions from specific and possibly severe conditions. Consequently, second admission to ED may be required to reach a diagnosis. As delay in diagnostics may lead to poor outcomes (including higher morbidity, mortality, prolonged hospitalization and higher costs of care), readmission rate has been one of the parameters used to evaluate the quality of care. While it has been well recorded and studied in elective surgery, the studies are few in the field of emergency medicine.

During the recent years in Finland, the emergency services have been reorganized and a new specialty of emergency medicine has been established. Emergency physicians have obtained a major role in EDs. Our aim was to evaluate the care, diagnostic accuracy and rate of readmissions in patients admitted to ED due to non-specific abdominal pain (NSAP) during the era of former and new ED organization.

Materials and Methods

All patients discharged with the diagnosis of NSAP during 2015 (former ED organization) and 2016 (new ED organization) in Tampere University Hospital were registered. Out of these, all patients readmitted to ED within 48 hours from the index admission with the diagnosis of NSAP or pelvic pain (ICD-10 codes R10.0, R10.1, R10.3 and R10.4) were included in the study. Planned readmissions were excluded. The number and reasons for readmissions, diagnostic accuracy and examinations performed were registered, and the findings between the two time periods were compared.

Results

Out of a total of 173,630 ED admissions, 10,609 patients (6%) were discharged with the diagnosis of NSAP. Median age was 32 years (range 0-98) and 60% were female. 313 of these (1.2%; median age 32 years (range 0-98), 59.8% female) were readmitted to ED within 48 hours. The readmission rate was highest (4.1%) among patients aged 18 years or less. Non-specific diagnoses were significantly less common in 2016 than in 2015 (n=7.1% vs. 5.2%, p<0.001). However, the rate of readmissions remained similar (3.0% vs. 2.9%, p=0.975). Again, the rate of computed tomography and ultrasonography remained equal. An improvement in the diagnostic accuracy was noted especially in patients with acute cholecystitis, which was the single most important reason (n=16; 9.4%) for ED readmissions during 2015.

Conclusions

Readmission rate among patients discharged from ED with the diagnosis of NSAP was surprisingly low. After the ED organizational change in our hospital the diagnostic accuracy during the index admission has improved, but no reduction in the rate of readmissions has been observed. Better availability of radiological imaging may have reduced the misdiagnoses of some conditions, such as acute cholecystitis.


Leena SAARISTO (Tampere, Finland), Mika UKKONEN, Johanna LAUKKARINEN, Satu-Liisa PAUNIAHO
12:30 - 12:40 #11029 - OP081 What are the factors that affect the institution of ceilings of treatment in the emergency department?
OP081 What are the factors that affect the institution of ceilings of treatment in the emergency department?

BACKGROUND: Ceilings of treatment are crucial early decisions aimed at improving the quality of care for patients in whom they are deemed appropriate. Decision making concerning limitation of potentially life prolonging treatments is often challenging. Knowledge of end of life issues and decision making involved is lacking, and no research into ED ceiling of treatment decision making has been conducted in the UK. A qualitative approach is needed to expand the limited literature and validate transferability of research to current UK practice. AIMS: To determine the factors that influence the institution of ceilings of treatment for patients presenting critically ill to the Emergency Department. METHODS: This qualitative study used a phenomenological approach to explore attitudes and factors considered important in driving end-of-life decision making by ED consultants. Semi-structured interviews were conducted until data saturation was achieved (n=15). Participants were recruited via convenience sampling and represented 5 EDs in the West of Scotland. Interviews were audio recorded, transcribed verbatim, and thematic analysis was carried out using NVivo. A reflexive diary was kept throughout the data collection and analysis process, and emergent themes were returned to participants to validate findings. RESULTS: We present a model of factors that influence ceiling of treatment decisions making. It was found that acute clinical factors and patient specific factors lay the foundations of ceiling of treatment decisions. Such case-specific information is heavily contextualised by patient and family wishes, collateral information, anticipated outcome and whether the patient is accepted for higher care. This process flows through a ‘filter’ of cultural and environmental factors. The overarching nature of patient benefit was found to be of key importance, framing all aspects of ceiling of treatment institution. Ultimately, all decisions determining an appropriate ceiling of treatment for a given patient resulted in one of three common patient pathways: full escalation, ward-based care or palliative care initiation. CONCLUSIONS: To our knowledge, this is the first investigation of factors that affect ED ceiling-of-treatment decision making in the UK. Key factors identified included acute clinical factors, patient specific factors, patient and family wishes, anticipated outcome and eligibility for higher care. Together with cultural factors, environmental factors and collateral information factors, these key themes are framed by patient benefit to establish an appropriate level of treatment. This may have importance as an educational tool and can act as a guide for physicians making end-of-life decisions in the E.D. How different factors are combined, their weighting and influence on the decision to institute ceilings of treatment is variable. Clinicians should be cognizant of these factors and their associated biases when making these challenging decisions.


Nathan WALZL (Glasgow, United Kingdom), Jessica JAMESON, John KINSELLA, David LOWE
Kokkali
14:10

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A33
14:10 - 15:40

Infectious Disease & Sepsis (Cutting Edge)

Moderators: Kurt ANSEEUW (Medical doctor) (Antwerp, Belgium), Christoph DODT (Head of the Department) (München, Germany)
Coordinator: Christoph DODT (Coordinator, München, Germany)
14:10 - 14:40 The septic patient with meningitis. Jeff PERRY (Physician) (Speaker, Ottawa, Canada)
14:40 - 15:10 Most effective strategies to detect sepsis early. Pr Lisa KURLAND (speaker) (Speaker, Örebro, Sweden)
15:10 - 15:40 Septic arthritis and osteomyelitis in the ED. Dr Thomas BEATTIE (Senior lecturer) (Speaker, Edinburgh, United Kingdom)
Trianti Hall

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14:10 - 15:40

Leadership (The Boss' Office)

Moderators: Raed ARAFAT (Romania), Robert LEACH (Head of Dept.) (BRUXELLES, Belgium)
Coordinator: Christoph DODT (Coordinator, München, Germany)
14:10 - 14:40 The value of team work. Michael RADEOS (Speaker, USA)
14:40 - 15:10 Effective & creative views of administrative power. Greg HENRY (Speaker, USA)
15:10 - 15:40 How to make the big jump forward -Tips & Tricks. Jan STROOBANTS (Head of the Emergency Department) (Speaker, Brecht, Belgium)
Mitropoulos

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C33
14:10 - 15:40

Cardiovascular (Game Changers)

Moderators: Basar CANDER (Turkey), Pr Martin MÖCKEL (Head of Department, Professor) (Berlin, Germany)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
14:10 - 14:40 Development of a national care system for cardiac syncope. Szabolcs GAAL (Deputy head) (Speaker, Budapest, Hungary)
14:40 - 15:10 Troponins and point of care troponins: what every emergency physician needs to know. Martin THAN (Speaker, New Zealand)
15:10 - 15:40 Cardiovascular Killers: Aortic Dissection. Dr David CARR (Associate Professor of Emergency Medicine) (Speaker, Toronto Canada, Canada)
Banqueting Hall

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D33
14:10 - 15:40

YEMD - Current Issues

Moderators: Dean DE MEIRSMAN (Emergency medicine resident) (Geel, Belgium), Basak YILMAZ (Faculty) (BURDUR, Turkey)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
14:10 - 14:40 Working in the ED of a Small Hospital: A Survival Guide. Eleni SALAKIDOU (Delegate) (Speaker, Heraklion, Greece)
14:40 - 15:10 Working in the ED of a Large Hospital: A Survival Guide. Incifer KANBUR (Assistant doctor) (Speaker, Istanbul, Turkey)
15:10 - 15:40 Working in the ED of a Hospital in war settings: A Survival Guide. Alba RIPOLL GALLARDO (Physician) (Speaker, Milan, Italy)
Skalkotas

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E33
14:10 - 15:40

Nursing session 3

Moderators: Stamatina IORDANOPOULOU (Greece), Door LAUWAERT (Manager) (BRUSSELS, Belgium)
14:10 - 14:40 A patient with malaria at the emergency department: a practice story. Christien VAN DER LINDEN (Clinical Epidemiologist) (Speaker, The Hague, The Netherlands)
14:40 - 15:10 Echoing away sepsis 2, welcoming sepsis 3. Georgios PAPAGEORGIOU (Nurse) (Speaker, Nicosia, Cyprus)
15:10 - 15:40 Hellenic Regulatory Body of Nurses: Project, "Health Education and Training in First Aids through the School, the Family, and the Community", 2014-2017. Tzannis POLYKANDRIOTIS (Speaker, Greece)
MC-3

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F33
14:10 - 15:40

Free Papers Session 10

Moderators: Pr Cem OKTAY (FACULTY) (ANTALYA, Turkey), Pr Riccardo PINI (Director, E.D. High Dependency Unit) (Florence, Italy)
14:10 - 14:20 #10835 - OP082 Acute kidney injury and mortality among patients with rhabdomyolysis.
OP082 Acute kidney injury and mortality among patients with rhabdomyolysis.

Acute kidney injury and mortality among patients with rhabdomyolysis

 Nielsen FE1,2, Cordtz J1,3, Rasmussen TB4, Christiansen CF4.

1Department of Emergency Medicine, Slagelse Hospital, Denmark. 2Institute of Regional Health Services Research, University of Southern Denmark. 3Department of Emergency Medicine, University Hospital of Zealand, Denmark. 4Department of Clinical Epidemiology, Aarhus University Hospital, Denmark.

 

Background

Acute kidney injury (AKI) is a life-threatening complication of rhabdomyolysis (RM). There is controversy if the degree of the initial creatine phosphokinase (CK) elevation is associated with the risk of AKI and death.

Purpose

To examine the risk of AKI, renal replacement therapy (RRT) and mortality among patients with RM and to evaluate the association between CK level and the risk of AKI, RRT and death.

Methods

Register-based study of adult patients admitted to hospitals in the region Zealand during November 1, 2011 to March 1, 2014 with CK levels higher than 1,000 U/L within 72 hours of admission. Information about CK and other laboratory data was obtained from a regional laboratory database. Data on medical history, medical treatment and survival were obtained from the Danish National Registry of Patients, the National Health Service Prescription Database and the Danish Civil Registration System. Patients with preexisting end-stage renal disease or acute myocardial infarction were excluded. AKI was defined according to Kidney Disease Improving Global Outcome. Logistic regression was used to compute odds-ratios (OR) with 95% confidence intervals (CI) comparing the risk of AKI, RRT and all-cause mortality according to CK-level adjusting for confounding.

Results

The study included 1,024 patients with a median age of 72.9 years. Median CK was 2,226 U/L, 831 (81.2%) patients with CK 1,000-5,000 U/L, 154 (15.0%) with CK 5,001-15,000 U/L and 39 (3.8%) with CK 15,001+ U/L. A total of 442 (43.2%) patients developed AKI within 30 days, and 42 (4.1%) required RRT during the first year. A total of 170 (16.7%) patients had died within 30 days and 277 (27.1%) had died within 365 days.  Twenty-seven (69.2%) patients with CK > 15,000 U/L developed AKI within 30 days compared to 62 patients (40.3%) patients with CK 5,000-15,000 U/L and 353 (42.5%) patients with CK < 5,000 U/L. Five (12.8%) patients with CK > 15,000 U/L required RRT within a year compared to 7 (4.6%) patients with CK 5,000-15,000 U/L and 30 (3.6%) patients with CK < 5,000 U/L. In multivariate analyses it was found that OR of AKI within 30 days was 2.6 (95% CI 0.9-7.3) and the OR of RRT within one year was 3.0 (95% CI 0.8-10.9) among patients with CK +15,000 U/L (CK < 5,000 U/L as reference). The CK level was not associated with the risk of death.

Conclusion

Our initial analyses showed that elevated initial CK values was not associated with death. However, elevated CK values was associated with increased risk of AKI and RRT, although estimates were statistically imprecise.


Finn Erland NIELSEN (Copenhagen, Denmark), Cordtz JOAKIM, Rasmussen THOMAS, Christian CHRISTIANSEN
14:20 - 14:30 #10907 - OP083 Emergency Department Utilization among Kidney Transplant Recipients in the United States.
OP083 Emergency Department Utilization among Kidney Transplant Recipients in the United States.

Introduction: Patients with End Stage Renal Disease (ESRD) use the emergency department (ED) at a 6-fold higher rate than U.S. adults.  No national studies have described ED utilization rates among kidney transplant (KTx) recipients, and the factors associated with higher ED utilization. A more definitive understanding of the trends, causes, and outcomes of ED utilization among KTx patients is necessary to identify the potentially modifiable factors and to identify opportunities for better care coordination, lower resource utilization, and improved quality of care. 

Methods: We examined a cohort of 132,725 incident adult KTx recipients in the United States Renal Data System, a comprehensive national database of ESRD patients in the US, from 2005-2013.  ED use, hospital admission, and diagnoses were obtained from the Medicare Physician/Supplier and Inpatient databases.  Multivariable Poisson regression was conducted to assess the association of relevant patient variables with each of the primary and secondary endpoints where appropriate. 

Results: Nearly half (46.1%) of KTx patients had at least one ED visit within the first post-transplant year (1.61 ED visits/patient year); 39.7% of ED utilizers were hospitalized in the first year post-transplant. ED visit rate was high in the first 30 days (5.26 visits/person year), but declined substantially thereafter (1.81 visits/person year (PY) in months 1-3; 1.13 visits/PY in months 3-12 post-transplant) (Figure 1). In multivariable analysis, factors associated with a lower ED utilization rate included preemptive transplantation (RR: 0.770, 95% CI: 0.751-0.790), peritoneal dialysis (RR: 0.859, 95% CI:  0.843-0.875), private insurance coverage, and transplant at high-volume centers (>200 transplants/year). Predictors of higher ED utilization rate included older age (RR: 1.010, 95% CI: 1.005-1.015 per 10 years), female sex (RR: 1.173, 95% CI: 1.159-1.187), comorbid medical conditions, Medicaid or Medicare insurance coverage, higher proportion of neighborhood poverty (RR: 1.002, 95% CI 1.001-1.002), longer dialysis vintage (RR: 1.302, 95% CI: 1.271-1.333 per 10 years), older donor age (RR: 1.002, 95% CI: 1.002-1.003, greater degree of HLA mismatch, longer index hospitalization (RR: 1.004, (%% CI: 1.004-1.004), delayed graft function (RR: 1.268, 95% CI: 1.251-1.285).  

Conclusions: ED utilization for KTx patients is three-fold higher than the general population, but less than half the rate for ESRD patients on dialysis. Policies and strategies addressing preventable ED visits have high potential for improvement and savings


Brendan LOVASIK, Justin SCHRAGER (Atlanta, USA), Rachel PATZER
14:30 - 14:40 #11548 - OP084 Short-term exposure to breathable particulate matter and stroke incidence.
OP084 Short-term exposure to breathable particulate matter and stroke incidence.

Introduction and objective:

Particulate matter (PM) with particle sizes less than 10 microns, which are known as breathable suspended particulates, can get deep into the lungs and cause a broad range of health effects, respiratory and cardiovascular particularly. Studies confirmed a strong association between air concentrations of PM and cardiovascular disease. On the other hand, it is still unclear if exposure to breathable (size 10 microns or less) PM leads to stroke events and whether the timing of exposure is associated with stroke risk. In this study we examined the association between occurrence of stroke and respirable PM air concentration.

Methods:

We retrospectively studied Emergency Department (ED) admission of acute stroke patients from Jan 2011 to Dec 2016. We registered occurrence of stroke compared to breathable PM (PM 10 and PM2.5) concentrations. Incidence of events was associated with PM levels on the day of onset and on the 3 days following PM elevation. PM concentrations were provided from local monitoring data from the Veneto Regional Agency for Prevention and Environmental Protection (ARPAV), classified accordingly with EU health based standards for pollutants in air (25 µg/m3 for PM2.5 and 50µg/m3 for PM10).

Results:

During the study period 2,590 stroke patients referred to our ED: 1,721 (66.4%) were ischemic and 869 (33.5%) were hemorrhagic. Gender (ischemic stroke: M: 49.3%; F: 51.7%; hemorrhagic stroke: M 51.6%; F: 48.4%) and age (ischemic stroke: 74 years, range: 18-102; hemorrhagic stroke: 68 years, range: 18-99) distribution were similar in the two groups. We did not observe any difference in stroke incidence with PM10 levels within or over the EU standards. PM2.5 air concentration over the EU standards revealed to be associated, acutely and on 3 following 3 days, with a higher incidence of ischemic stroke (+38.4%) and hemorrhagic stroke (+12.5%), compared to stroke events occurred on the within the EU standards PM2.5 levels days. Also in this case no age and gender differences were observed between the two study groups.

Conclusions:

Medical researches show that the risk for various health impacts increases with air particulate matter exposure but there is little evidence to suggest a threshold below which no adverse health effects would be anticipated. It has also been shown that the health risks would be higher for those particles with particle sizes of 2.5 microns or less, which are commonly referred to as fine suspended particles or PM2.5. Our study suggests that short-term exposure to elevated PM 2.5 is associate with a higher incidence of ischemic stroke whereas the association with hemorrhagic stroke is less clear.


Massimo ZANNONI (VERONA, Italy), Manuel CAPPELLARI, Gianni TURCATO, Lucia ANTOLINI, Alberto RIGATELLI, Giorgio RICCI
14:40 - 14:50 #11741 - OP085 Thrombolysis for Acute Ischemic Stroke in the Emergency Department(ED) is safe. comparative study : ED versus stroke unit.
OP085 Thrombolysis for Acute Ischemic Stroke in the Emergency Department(ED) is safe. comparative study : ED versus stroke unit.

Introduction : Stroke has a major impact on individual lives and the nation's health and economy. It is the third  cause of death in the world, and a major cause of adult disability. The therapeutic revolution has completely changed the functional and vital prognosis of patients with stroke due to reperfusion, and particular intravenous stroke thrombolysis with rt-PA. Because «  time is brain  », thrombolysis should be performed as early as possible. Istablishing specific neurovascular units may improve  the management of acute ischemic stroke. However, initiation of thrombolysis in the emergency room is still controversed.

Objective : The objective of this study is to compare the results of intravenous stroke thrombolysis performed in the ED versus that performed in the department of neurology in terms of delays, prognosis and complications .    

Methods : we made a  transversal analytical study in our ED during 2 years  . In this study we analysed all the patients alerted for thrombolysis. We made two groups (group 1 = thrombolysis performed in the ED and group 2 = thrombolysis performed in the neurology department). All patients underwent brain CT in the ED. All delays were noted, in particular the delay "door to needle". The NIHSS score before thrombolysis, H1, H6 and H24 post thrombolysis and the occurrence of hemorrhagic transformation were noted too.

Results : 520  patients were included, only 188 patients were alerted for thrombolysis protocol. 60 patients underwent thrombolysis divided into 2 groups : group 1 in the ED and group 2 in the neurology department. The mean age was 64±12 years in group 1 vs 67±13 years in group 2. There wis no great gender predominance in the 2 groups.The time onset to needle was 2h50±30mn in group1 and 4h10±20mn in group2( p=0.007). There is a significant difference in the mean door-to-needle time between 2 groups : 80±33mn in groupe 1 vs 173±39 in group2 (p=0.0001). There is no significant difference between 2 groups in NIHSS score (at admission,at H1 and H6 post thrombolysis) and  in good early outcome. The risk of intracerebral hemorrahge is more important in group 2than group 1 (10% vs 3% respectively with a significant difference p=0.004).

Conclusion : the beneficial effect of thrombolysis on mortality and functional outcome  in patients with acute ischemic stroke may be improved  when it is performed early and within the recommended delays.


Rabaa SABBEGH, Asma ZORGATI, Rim YOUSSEF, Chawki JEBALI, Riadh BOUKEF, Ali OUSJI (Sousse, Tunisia)
14:50 - 15:00 #10975 - OP086 Oligoanalgesia in the emergency department waiting room: predictive factors.
OP086 Oligoanalgesia in the emergency department waiting room: predictive factors.

Background

 

Pain is the leading symptom in emergency departments (ED). Due to overcrowding, some patients are oriented to the waiting room and their medical evaluation deferred.  In order to ease analgesia in the waiting room, we have enforced a dedicated pain management protocol allowing nurses to administer analgesia when indicated. The objectives of this study were: (1) to measure treatment administration to patients with documented pain upon arrival; (2) to identify predictors of non administration of pain treatment (oligoanalgesia) ; (3) to evaluate pain protocol adherence by nurses.

 

Methods

Prospective observational study in the ED of a primary and tertiary urban teaching hospital with an annual census of 68‘000 patients.  All patients with a pain score documented on arrival and oriented to the waiting room were eligible.  Demographic characteristics, pain severity scores (0 to 10), time delays, triage complaint and emergency level as well as medication use were extracted from the electronic patient records.  Univariate and multivariate analyses were performed to identify predictors of oligoanalgesia.

Results

During a three months period, 2’371 patients were included. Their mean age was 49 years and the majority were male (51%). The leading triage complaint was abdominal pain (30.3%). Pain treatment was given to 734 patients (31%). Treatment was more frequently administered (43%) for pain severity scores > 5 than for lower acuity scores (16%, p <.0001). Time to treatment was 60 minutes (IQR 20-121) and 16 minutes (IQR 7-40) for pain scores < 5 and > 5 respectively (p =.01). Patients with an initial pain score < 5 were treated in accordance to the nurses’ protocol in 73.1% of the cases. This rate dropped to 32% in patients with initial pain scores ≥ 5.

In multivariate analyses, risk predictors for non treatment of pain in the waiting room were:

age > 80 y (OR 2.32 ; 95% CI 1.49-3.60), admission by ambulance (OR 1.50 ; 95% CI 1.12-2.01), higher triage severity level (OR 1.67 ; 95% CI 1.32-2.11), initial pain score < 5 (OR 3.78 ; 95% CI 2.99-4.76), waiting room LOS < 30 minutes (OR 2.79 ; 95% CI 2.06-3.78). When compared to pain suggestive of renal colic, pain associated with a neurological complaint (OR 6.54; 95% CI 2.88-14.84) was the most important predictor for oligoanalgesia. In the multivariate model neither waiting room occupancy nor ED’s patients’ load were significantly associated with non treatment.

 

Conclusion

 

In the waiting room of our ED, the proportion of patients receiving pain medication is low.  Adherence to our pain protocol is insufficient. Older patients, patients with low intensity pain scores and presenting complaints other than renal colic are at higher risk of treatment abstention independently of emergency room workload. These patients should be targeted by specific interventions.


Mio GOBET (Geneva, Switzerland), Olivier RUTSCHMANN, Francois SARASIN, Villar ADOLFO, Bernard MUGNIER, Majd RAMLAWI
15:00 - 15:10 #11074 - OP087 Midazolam or haloperidol premedication in prevention of ketamine induced agitation in emergency department: A randomized double blind clinical trial.
OP087 Midazolam or haloperidol premedication in prevention of ketamine induced agitation in emergency department: A randomized double blind clinical trial.

Introduction: The effective and safe sedation for painful procedures in the emergency department is one of the principal concerns of emergency physicians. The sedative agent must be one with rapid onset, steady effects, quick recovery, and acceptable side-effects. Ketamine is an ideal sedative agent but emergency physicians are reluctant to use it due to fear of recovery agitation. It has been proposed to use other drugs specifically benzodiazepines as premedication to reduce the agitation.The goal of our study was to evaluate the effect of midazolam and haloperidol premedication on ketamine induced agitation, and also the emergency physician satisfaction with the procedure.

Method: This was a randomized double-blind placebo-controlled trial to assess the efficacy of ketamine premedication by midazolam or haloperidol, in reducing agitation incidence and severity. The study was approved by the university ethics committee. The samples were chosen from patients older than 18 of either sex who needed sedation in emergency department at Sina Hospital. Patients who had any contraindication to ketamine, midazolam or haloperidol were excluded.

Patients randomly allocated in 3 groups, Arm 1: patients received 2 intravenous injections of distilled water (1cc and 0.05 cc/kg) 5 minutes prior to receiving a sedative dose of 1 mg/kg IV ketamine.  Arm 2: patients received 2 intravenous injections, 1cc of distilled water and 0.05 mg/kg midazolam, 5 minutes prior to ketamine. Arm 3: patients received 2 intravenous injections, 0.05 cc/kg of distilled water and 5mg of haloperidol, 5 minutes prior to ketamine.

Level of sedation and agitation were assessed using RASS score (after 5, 15 and 30 minutes of ketamine injection) and Pittsburgh Agitation Scale. Also, physician satisfaction with the sedation procedure was evaluated using Clinician Sedation Satisfaction Index(CSSI).

 Results: 180 sample enrolled from July 2016 to March 2017.The incidence of Recovery Agitation, was 66% in the group that received no premedication and 20% in both groups that received premedication, whether midazolam or haloperidol (p<0.001). Also, agitation severity (mean PAS score of 3.37) in the group which only received ketamine was much higher in comparison to the other two groups (mean PAS score of 0.65 and .063) (p<0.001). The comparison between the two intervention groups (midazolam versus haloperidol) showed no significant difference in agitation severity (mean PAS score of 0.65 versus .063).The score of physician satisfaction was significantly higher in the field of reduced agitation in premedicated group (p<0.001).

Discussion: We found a significant reduction in recovery agitation of ketamine by using midazolam or haloperidol as premedication. Our results were similar to most previous studies about the effect of BZDs. However, few studies have been done about the effect of haloperidol on reducing ketamine induced agitation.

Trial registration: ClinicalTrials.gov NCT02909465


Narges AKHLAGHI (Tehran, Islamic Republic of Iran), Pooya PAYANDEMEHR, Mehdi YASERI, Ali ABDORAZAGH NEZHAD
15:10 - 15:20 #11098 - OP088 Retrospective chart review exploring safety profile of ketamine-propofol in the pediatric emergency room.
OP088 Retrospective chart review exploring safety profile of ketamine-propofol in the pediatric emergency room.

Background

Procedural sedation and analgesia (PSA) is routinely used in pediatric patients for painful procedures. The use of IV ketamine and propofol (‘ketofol’) for PSA is established in adult patients and has been shown to be safe and effective. The purpose of this study was to analyze the safety of ketofol in pediatric patients. 

Methods

This was a single-center retrospective study at a Canadian pediatric tertiary care centre. Patients were included if they were less than 18 years old at time of PSA, and received ketofol within the period January 1, 2011 to December 31, 2016. Adverse events, interventions and recovery times were captured.

Results

233 charts were analyzed, of which 163 met the inclusion criteria. 65% of the patients were male. 9% had an underlying medical condition, with 6% of all patients having asthma. The average age was 9.5 years (range 2 months to 18 years).

The indications for PSA using ketofol were usually fracture or joint reduction (63%) and laceration repair (18%). Other indications included plastics procedures (6%), lumbar puncture (4%), abscess incision and drainage (4%), burn/wound debridement (3%), and CT sedation (1%). The median procedure time was 13 minutes (interquartile range 8-22 minutes) and median time to recovery was 30 minutes (IQR 21-46 minutes).

The major adverse reaction experienced was hypoxia (10%) with resolution by conservative measures (stimulation, airway positioning and supplemental oxygen). Two cases with hypoxia required bag mask ventilation and none required intubation. Only one case had a severe adverse reaction (laryngospasm and hypotension), which resolved with supplemental oxygen, bag mask ventilation, and fluid bolus. 3% of cases had nausea or vomiting. No cases had hypersalivation, bradycardia, emergence reaction, or seizure. There was no relation to the dose of either ketamine or propofol to the observed adverse reactions. Three cases required re-sedation due to failure of previous sedation. Two of these cases failed intranasal sedation or local block and then received ketofol. Only one sedation failure was due to inadequate sedation from ketofol with repeat sedation requiring additional adjunct of midazolam.

Subgroup analysis on patients less than 24 months yielded no additional risk for adverse events or failed sedation.

Discussion

This is the largest study to date analyzing the safety profile of ketofol in the pediatric population. Overall, ketofol is a safe and effective combination for pediatric PSA. Major adverse effects were lower than previous smaller studies. Additionally, mean recovery time was similar to published literature.


Vidushi KHATRI, Mohammed ALROWAYSHED (Hamilton, Canada), Leanne PATEL, Angelica RIVAS, Patrick TANG, Rahim VALANI
15:20 - 15:30 #11233 - OP089 Low-dose Ketamine in association with IV morpnine for acute pain in emergency department.
OP089 Low-dose Ketamine in association with IV morpnine for acute pain in emergency department.

Background:

Acute pain is the most frequent complaint in emergency department (ED), but its management is often  complex, placing patients at risk of oligoanalgesia. Emergency physicians are considering alternative, complimentary medications, such as ketamine, combined with traditional drugs such as opioids to achieve multimodal analgesia in the acute setting.

The aim of this study was to determine the effectiveness of low-dose ketamine as an adjunct to morphine versus standard care with morphine alone for the treatment of acute moderate to severe pain among ED patients.

Methods:

We conducted a double-blind, randomized, placebo-controlled trial at the ED, over a six-month period. Eligibility criteria were: age between 18 and 65, acute moderate or severe pain (the numerical pain rating scale (NRS)>5) who require morphine. Patients were randomized on three study groups: standard group receiving morphine and normal saline placebo; group1 receiving morphine and 0.15 mg/kg ketamine and group2 receiving morphine and 0.3 mg/kg ketamine. Pain was assessed at 30, 60 and 120 minutes after drug administration; rescue analgesia consisting on 0.5mg/kg morphine was prescribed if the reduction of pain was lower than 50%. The occurrence of adverse events was also measured.

Results:

One hundred twenty patients were enrolled: 41 patients in standard group, 42 patients in both groups 1 and 2. There were no difference between the three groups in baseline NRS, as well as in the demographic and clinical characteristics. The most common cause of pain was nephritic colic in 50.4% of patients. NRS improvement was more important and rapid in group 2 compared to the other groups with a statistically significant difference at 120 minutes. The SPID was higher in ketamine’s groups compared to standard group. Among patients receiving rescue analgesia, 28 were in standard group, 24 in group1 and 5 in group2 (p<0.001). The total  dose of morphine was significantly greater in morphine group comparing to the ketamine groups. There was no difference in side effects between the three groups. More participants in the ketamine groups reported minor neuropsychiatric adverse effects  such as dysphoria and dizziness. Patients from placebo group developed more digestive events such as nausea and vomiting.

Conclusion:

Low doses of ketamine are well tolerated and present efficient analgesic effect in adjunction to morphine compared to morphine alone for pain management in ED. The dose of 0.3mg/kg seems more effective than 0.15 mg/kg but might cause more adverse neuropsychiatric events.


Khaoula RAMMEH, Hajer KRAIEM (Sousse, Tunisia), Sana MABSOUT, Majdi OMRI, Mariem KHROUF, Mehdi METHAMEM
15:30 - 15:40 #11234 - OP090 Low-dose Ketamine in association with IV morpnine for acute pain in emergency department.
OP090 Low-dose Ketamine in association with IV morpnine for acute pain in emergency department.

Background:

Acute pain is the most frequent complaint in emergency department (ED), but its management is often  complex, placing patients at risk of oligoanalgesia. Emergency physicians are considering alternative, complimentary medications, such as ketamine, combined with traditional drugs such as opioids to achieve multimodal analgesia in the acute setting.

The aim of this study was to determine the effectiveness of low-dose ketamine as an adjunct to morphine versus standard care with morphine alone for the treatment of acute moderate to severe pain among ED patients.

Methods:

We conducted a double-blind, randomized, placebo-controlled trial at the ED, over a six-month period. Eligibility criteria were: age between 18 and 65, acute moderate or severe pain (the numerical pain rating scale (NRS)>5) who require morphine. Patients were randomized on three study groups: standard group receiving morphine and normal saline placebo; group1 receiving morphine and 0.15 mg/kg ketamine and group2 receiving morphine and 0.3 mg/kg ketamine. Pain was assessed at 30, 60 and 120 minutes after drug administration; rescue analgesia consisting on 0.5mg/kg morphine was prescribed if the reduction of pain was lower than 50%. The occurrence of adverse events was also measured.

Results:

One hundred twenty five patients were enrolled: 41 patients in standard group, 42 patients in both groups 1 and 2. There were no difference between the three groups in baseline NRS, as well as in the demographic and clinical characteristics. The most common cause of pain was nephritic colic in 50.4% of patients. NRS improvement was more important and rapid in group 2 compared to the other groups with a statistically significant difference at 120 minutes. The SPID was higher in ketamine’s groups compared to standard group. Among patients receiving rescue analgesia, 28 were in standard group, 24 in group1 and 5 in group2 (p<0.001). The total  dose of morphine was significantly greater in morphine group comparing to the ketamine groups. There was no difference in side effects between the three groups. More participants in the ketamine groups reported minor neuropsychiatric adverse effects  such as dysphoria and dizziness. Patients from placebo group developed more digestive events such as nausea and vomiting.

Conclusion:

Low doses of ketamine are well tolerated and present efficient analgesic effect in adjunction to morphine compared to morphine alone for pain management in ED. The dose of 0.3mg/kg seems more effective than 0.15 mg/kg but might cause more adverse neuropsychiatric events.


Khaoula RAMMEH, Hajer KRAIEM (Sousse, Tunisia), Sana MABSOUT, Majdi OMRI, Mariem KHROUF, Mehdi METHAMEM
Kokkali
15:45

"Tuesday 26 September"

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PH5 - S1
15:45 - 16:05

E-Poster Highlight Session 5 - Screen 1

Moderators: Felix LORANG (Consultant) (Erfurt, Germany), Judith TINTINALLI (Professor) (Chapel Hill NC, USA)
15:45 - 15:50 #9803 - COPEPTIN, MYELOPEROXIDASE AND PRO-ADRENOMEDULLIN FOR CHEST PAIN IN CHRONIC RENAL FAILURE PATIENTS.
COPEPTIN, MYELOPEROXIDASE AND PRO-ADRENOMEDULLIN FOR CHEST PAIN IN CHRONIC RENAL FAILURE PATIENTS.

Objectives: Copeptin, Myeloperoxidase and Pro-adrenomedullin have emerged as potential biomarkers for diagnosis and prognosis of acute coronary syndrome. However, their applicability with chronic renal failures remains unknown as these patients were excluded from the previous studies. Our objective was to determine the superior novel cardiac marker to predict 30-day and 6-month adverse cardiac event (ACE) as defined as cardiac related death, myocardial infarction and ventricular fibrillation.

Methods: A prospective observational study was carried out. Patients were included if they presented to the ED with a chief complaint of chest pain and had chronic renal failure as defined as a serum creatinine of more than 130umol/L. Copeptin, Myeloperoxidase and Pro-adrenomedulin assays were performed. Occurrence of ACE was traced from review of the patients’ case records and checking of the registry of deaths.

Results: Seven hundred and twenty four patients were recruited with a median age of 67. 60.6% of the study population were male. 88.3% of the population had CKD stage 4 and 5, with 33.5% on dialysis. The rates of ACE at 30-day and 6-month were 15.1% and 21.7% respectively. All readings of the 3 biomarkers were not significantly different in patients with ACE compared to those without at both 30-day and 6-month. The AUCs for Copeptin, Myeloperoxidase and Pro-adrenomedullin are 0.53, 0.50 and 0.45 respectively (p all >0.05).

Conclusions: The performance the biomarkers was poor attributable to the lack of specificity for acute coronary syndrome as elevated levels could be due to other causes in patients with chronic renal disease. Routine testing cannot be recommended.


Jen Heng PEK (Singapore, Singapore), Swee Han LIM
15:50 - 15:55 #11138 - Finnish Prehospital Stroke Scale – a simple tool for paramedics for rapid detection of both thrombectomy and thrombolysis candidates.
Finnish Prehospital Stroke Scale – a simple tool for paramedics for rapid detection of both thrombectomy and thrombolysis candidates.

Background:
 
In ischemic stroke caused by a thrombosis of a large brain artery, IV-thrombolysis (IV-tPA) appears ineffective, while mechanical thrombectomy (MT) is reported to be a powerful tool to open the occlusion (1). However, the favorable effect of recanalization is highly time-dependent (2). Previously validated and generally used stroke signs (face-arm-leg-speech-visual disturbance) recognize stroke in general. Furthermore, conjugate eye deviation (CED) is highly related to large vessel occlusion (LVO). Currently, patients with suspected stroke are transported to the nearest hospital with facilities for IV-tPA but not necessarily for MT. Hence, this can cause significant treatment delay.  We hypothesized that combining general stroke signs with CED will produce an easy-to-use prehospital stroke scale for prehospital use by emergency medical services (EMS), recognizing both stroke in general and LVO separately.  Thus, unnecessary visits to non-tertiary hospitals could be avoided.
Methods: We retrospectively analyzed n=856 consecutive patients with prehospital Code Stroke (thrombolysis candidate). National Institutes of Health Stroke Scale (NIHSS) was executed on patient arrival. Computed tomography (CT) was performed for all patients and CT angiography based on clinical decision. With random forest analysis and deviance analysis of the general linear model we confirmed superiority of NIHSS ‘Best Gaze’ over other NIHSS items in LVO detection.

Results: NIHSS ‘Best Gaze’ had the best predictive value of NIHSS items in detecting LVO of the anterior circulation. Based on this and generally used stroke signs we presented Finnish Prehospital Stroke Scale (FPSS) including dichotomized face drooping, extremity weakness, speech difficulty, visual disturbance and CED.  “Face droop”, “extremity weakness”, “disturbed speech” and “disturbance of vision” give each one point while “forged or partial conjugated gaze deviation to one side” gives four points. FPSS with combined score values of 1-4 indicates a thrombolysis candidate whereas values 5-8 indicate a thrombectomy candidate.   FPSS detected LVO with a sensitivity of 54%, specificity of 91%, PPV 48%, NPV 93%, and LR of 6.2 which are comparable to previous scales aimed to detect LVO only.
Conclusions: FPSS is simple to use and with dichotomized items, easily implementable for emergency medical services and emergency response centers. Furthermore, the high specificity of FPSS for LVO enables direct transfer of candidates for endovascular treatment to tertiary stroke centers. Containing a clear cut off point FPSS is convenient regardless of operational environment. Based on CED, FPSS can recognize LVO and on general stroke signs (face-arm-leg-speech-visual disturbance) stroke in general, thus aiding patient logistics in stroke management.


Jyrki OLLIKAINEN (Tampere, Finland), Heikki JANHUNEN, Juho TYNKKYNEN, Kalle MATTILA, Minna HÄLINEN, Niku OKSALA, Satu-Liisa PAUNIAHO
15:55 - 16:00 #11251 - Conditions for laryngeal mask airway placement: a comparison of blind insertion and insertion with the use of a laryngoscope.
Conditions for laryngeal mask airway placement: a comparison of blind insertion and insertion with the use of a laryngoscope.

In emergent airway management, the laryngeal mask airway (LMA) have served as a bridge between endotracheal intubation and the face mask. For achieving the ideal anatomical position of the LMA, various trails, including insertion with the use of laryngoscope, have been described. Yet, except fiberoptic assessment, reliable tests for this technique of correct placement of LMA are not established.

Recently, oropharyngeal leak pressures are commonly performed with the LMA to indicate the degree of airway protection, the feasibility for positive pressure ventilation and the likelihood for successful supraglottic airway placement

The objective of this randomized prospective study was to assess the efficacy of insertion techniques, blind insertion and insertion with laryngoscope. The primary outcome was the measurement of oropharyngeal leak pressure with the two techniques. The secondary outcomes were the success rate on first attempt.

Method

Approval was obtained from the IRB, a prospective comparison of 100 patients divided into 2 groups (50 with blind technique and 50 with the laryngoscope technique) were evaluated. A standard anesthetic protocol without muscle relaxant was followed. After loss of consciousness, a LMA was inserted using the blind approach in blind insertion group or using laryngoscopy in laryngoscope group.

The oropharyngeal leak pressure was performed by closing the expiratory valve of the circuit at a fixed gas flow of 6 L/min and noting the airway pressure at which gas leaked into the mouth. The failure of first attempt insertion was recorded. Failed insertion was defined by any of the following criteria: failed passage into the pharynx; malposition; ineffective ventilation (maximum expired tidal volume < 6 ml/kg). We analyzed the data with SPSS version 17 (SPSS Inc., Chicago, Illinois, USA). Continous data were analyzed using Student’s t-test. Nonminal data were analyzed with x2 test. A p value less than 0.05 was considered significant.

Result

There was no significant difference between two groups on oropharyngeal leak pressure (18.4 ± 5.4 mmHg in blind group vs 20.6 ± 7.1 mmHg in laryngoscope group, p=0.16) and success rate on first attempt (89.2 % in blind group vs 94.5% in laryngoscope group, p=0.46).

Conclusion

In terms of oropharyngeal leak pressure, insertion with laryngoscope did not show any superiority compared to blind insertion. Blind insertion technique is easier and simpler method for insertion of LMA and has a reasonable success rate, so it is recommended to be used.


Sung Yong PARK (Suwon, Republic of Korea), Jong Yeop KIM, Sook Young LEE, Bong Ki MOON, Sang Ki MIN
16:00 - 16:05 #11340 - Evaluation of the practice of lumbar puncture in the resuscitation of emergencies.
Evaluation of the practice of lumbar puncture in the resuscitation of emergencies.

Introduction: Lumbar puncture (PL) is a common diagnostic procedure in the management of patients admitted to emergency departments. Its main indication is the search for an infection of the Central nervous system. Few epidemiological data are available in the literature concerning the use of PL, its efficiency and the populations benefiting from this review.

Purpose of Work: The objective of our work is to study the profiles of the patients benefiting from the lumbar puncture and to evaluate the predictive factors of its positivity, in order to propose a decision algorithm of the realization of the lumbar puncture in the emergencies.

Materials and methods: We carried out a retrospective study over a period of 4 years (between January 1, 2013 and December 31, 2016), within the adult emergency resuscitation department of the Ibn Rochd University Hospital Center. The inclusion criteria: Patient benefiting from a PL at the time of his/her management in the emergencies, taking into account the first effective PL carried out for the same patient during the same passage.  Excluded:   Patients who had CSF analysis by a technique other than lumbar puncture,Patients who had CSF analysis by PL without passing through the adultSAU.Epidemiological, clinical, biological, radiological and evolutionary characteristics were analyzed, according to a global descriptive study and a multivariate analysis and a univariate analytical study aiming at assessing the association between two variables.

Results: 590 patients received a PL after admission to the emergency room, representing 4.11% of patients admitted to emergency departments during study periods. Nearly 34.2% of the PLs performed were contributory and confirmed a diagnosis of meningitis (174 cases), meningeal haemorrhage (16 cases) or polyradiculoneuritis (12 cases). These contributory PLs were mainly related to infectious meningitis. The main diagnoses found in the presence of non-contributory PLs were related to neurological pathologies (convulsions and strokes) and infectious pathologies outside the central nervous system. In this work, it was found that a history of head trauma, presence of obliteration, clinical association of fever-headache, fever-meningitis stiffness, and fever-headache-meningeal stiffness are predictive factors, A positive lumbar puncture. Concerning cerebral imaging, 83.73% of patients with lumbar puncture had a CT scan. The importance of using the brain scan seems to be excessive, and the expectation of the result may be the cause of a delay in diagnosis and management leading to a situation prejudicial to the patient.

 Conclusion: A decision algorithm for performing lumbar puncture in emergency departments is proposed, based on the existence of factors predictive of CSF positivity, whether signs of gravity are present or not. And the key message is not to delay the administration of antibiotics to any suspected cases of community meningitis.


Mezgui OTHMAN (CASABLANCA, Morocco), Khaleq KHALED, En_Noqobi JAMAL
E-Poster Area

"Tuesday 26 September"

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PH5 - S2
15:45 - 16:05

E-Poster Highlight Session 5 - Screen 2

15:45 - 15:50 #10089 - Evaluating the Implementation of a Sepsis Pathway in the Emergency Department.
Evaluating the Implementation of a Sepsis Pathway in the Emergency Department.

 

Background: The importance of early management of sepsis is well known and has led to increased efforts in improving the recognition of and response to septic patients in emergency departments    

Objectives: To evaluate the impact of utilising a Sepsis Pathway Program, aimed at improving recognition of and response to septic patients, in a metropolitan Emergency Department 

Method: Following the introduction of a Sepsis Pathway Program in June 2015, a review of patients presenting to the emergency department of Casey Hospital, Victoria from June to December 2015 with sepsis was conducted. Main outcome measures were: time to antibiotic administration and to lactate measurement; rate and duration of intensive care admission; in-hospital mortality, and total duration of hospital admission. Outcomes were compared to a retrospective review of septic patients presenting to emergency from June to December 2014.

Results: The review included 171 patients in 2014 and 130 patients in 2015. The median time to antibiotic administration was significantly shorter in the post-intervention group (102 minutes vs. 190 minutes, p<0.05. The time to lactate measurement, number and duration of intensive care admissions, in-hospital mortality and total length of stay was not significantly different between the two groups.  

Conclusion: Implementation of the Sepsis Pathway Program resulted in earlier administration of antibiotics in septic patients presenting to the emergency department. Although a significant difference in secondary outcomes were not observed in this study, further evaluation in a larger multi-centre study may be warranted.


Dr Pourya POURYAHYA (Melbourne, Australia), Judy CHOW, Alastair MEYER, Neil GOLDIE
15:50 - 15:55 #11037 - Can differences in the management of children with shortness of breath be explained by disease severity alone?
Can differences in the management of children with shortness of breath be explained by disease severity alone?

Introduction

The aim of this study was to assess differences in population, management and outcome of children with respiratory complaints in 5 different European emergency departments

Methods

This study was part of the TrIAGE project, a prospective observational study consisting of a large cohort of children visiting the emergency department (ED) in 5 different hospitals in 4 European countries (UK, Austria, Portugal, the Netherlands). Data collection consisted of routinely recorded patient data, automatically extracted from electronic medical records. Data harmonization and quality checks were performed.  We included all children aged The associations between population (age, hospital, triage urgency, vital signs) and management (lab, imaging, inhalation medication and hospital admission) were assessed using a logistic regression model.

Results

In total, 13.552 children with shortness of breath were included. Of those, 55% (8.560) were categorized as urgent. This ranged from 13% in a low-urgency setting to 80% in a high-urgency setting.
The majority of children was below the age of 5 years (77%, range 73-84%).

Regarding vital signs, 41% of the total population had an abnormal respiratory rate according to APLS normal values, 9% had an abnormal oxygen saturation and 53% showed increased work of breathing.
Lab tests were performed in 16% of children (range between hospitals: 8-32%, adjusted odds ratio 5.6, 95% CI 4.0-7.9) and an X-ray was performed in 19% (range: 8-33%, adjusted odds ratio 8.6, 95% CI 6.4-11.6).
Forty-six procent of all children were treated with inhalation medication (range: 21-61%, adjusted odds ratio 0.5, 95% CI 0.3-0.7) and 19% was admitted (range 8-47%, adjusted odds ratio 0.1, 95% CI 0.1-0.2). Two hundred and five children (1.5%) were admitted to the ICU (range: 0.1-9%, adjusted odds ratio 43.4, 95% CI 13.4-140.7).

Patient characteristics (age, gender, urgency, presence of fever, abnormal vital signs) could explain part of the observed differences in management. However, after correcting for these population characteristics, we still observed substantial differences between hospitals concerning the management of these children.

Conclusion & discussion

European EDs differ substantially regarding the management of children with respiratory complaints, even when correcting for triage urgency or age. Possible explanations might be other aspects of patient characteristics such as underlying problem or comorbidity, or differences in local practice and use of different guidelines. 


Dorine BORENSZTAJN (Rotterdam, The Netherlands), Joany M ZACHARIASSE, Susanne GREBER-PLATZER, Claudio F ALVES, Paulo FREITAS, Frank J SMIT, Johan VAN DER LEI, Ewout W STEYERBERG,, Ian MACONOCHIE,, Henriëtte A MOLL
16:00 - 16:05 #11395 - Prospective study of the association of coagulopathy and isolated traumatic brain injury.
Prospective study of the association of coagulopathy and isolated traumatic brain injury.

The complex pathophysiological mechanisms behind coagulopathy that occurs after traumatic brain injury are multifactorial and remains poorly defined  , but many studies have shown the progression of parenchymal lesions particularly in patients with coagulopathy . Disorders of coagulation may be amenable to treatment  , adequate and prompt intervention may prevent secondary complications and poorer outcome.

Objectives : The purpose of this study is to evalute the association of coagulopathy and isolated traumatic brain injury as regard its frequency and outcome for patients who developed coagulopathy .

Patients : this prospective study was conducted to include 60 patients with isolated traumatic brain injury admitted to the emergency department of Alexandria main university hospital within 24 hours of trauma . Patients with known coagulopathy , on anticoagulants therapy , or those with intra abdominal collection , hemothorax or other injuries that affect coagulation were excluded from the study.

Methods : Primary survey and secondary survey were done for those patients . Radiological investigations were done including CT brain to exclude other sources of bleeding which can lead to coagulopathy . This also includes laboratory tests to asses coagulation as INR , platelet count , PTT and FDP for those who showed abnormality with the previous three tests .

Results : The frequency  of coagulopathy among those 60 patients was  8.3% . In this study 80% of cases who developed coagulopathy had severe traumatic brain injury and 20% had moderate TBI , but non of the  cases who developed coagulopathy had mild TBI .  Brain edema was the most common CT finding in patients with coagulopathy following TBI as it was present in 80% of cases . Acute Subdural hematoma is the second most common CT  finding in those who developed coagulopathy occured in 60% of those patients . Intra ventricular hemorrhage and hemorrhagic contusion occured in 40% of cases .All patients with coagulopathy had FDP > 10 mic/ ml and INR >1.3 , while PTT> 34 seconds in 80% of cases who developed coagulopathy.  Platelets count  < 100,000 cell/mm3 was present only in 40% of patients who developed coagulopathy . As regard outcome in ED  80% of cases who developed coagulopathy had deterioration of their GCS, while only 40 % of those who developed coagulopathy had disseminated intravascular coagulopathy .Also 80% of those had progressive hemorrhagic lesion on follow up CT  brain .

 Conclusion : coagulopathy occurs frequently after TBI . Coagulopathy is much more pronounced in patients with severe TBI than in patients with mild or moderate TBI .  Brain edema and acute subdural hematoma ate the most common CT finding in patients with coagulopathy after TBI . Not all cases of TBI  that had high levels of FDP had disseminated intravascular coagulopathy. 


Asmaa RAMADAN (Alexandria, Egypt), Ahmed FARHOUD, Eman TAYAE, Ahmed MARIE
E-Poster Area

"Tuesday 26 September"

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PH5 - S3
15:45 - 16:05

E-Poster Highlight Session 5 - Screen 3

15:45 - 15:50 #10506 - Prognostic analysis of pulmonary contusion in severe head trauma patients.
Prognostic analysis of pulmonary contusion in severe head trauma patients.

Introduction:

Severe head trauma is a common reason for patient’s admission to the intensive care unit and it is the leading cause of death in young adults. The outcome of these patients depends on many factors such as cerebral hypoxia. Pulmonary contusion can cause an acute respiratory failure that aggravates head trauma.

Study objective:

To evaluate the impact on morbidity and mortality of pulmonary contusion in patients admitted for severe head trauma.

Patients and methods:

This was a retrospective study performed in the emergency and intensive care department in the regional hospital of Zaghouan. The patients were recruited during 3 years, from January 2013 to December 2015. All adult patients admitted for severe head trauma (Glasgow coma score (GCS) 8) were included and evaluated by quantified injury severity scores including APACHE2, GCS, ISS, TISS. The diagnosis of pulmonary contusion was based on the history of blunt chest trauma and the appearance of four types of lesions on chest CT scans. Hospital length of stay, mortality rate, incidence of adverse events including pneumonia, ARDS and shock were recorder and compared into the tow groups (with or without pulmonary contusion).

 Results:

During the study period, 104 patients were included. The diagnosis of pulmonary contusion was retained in 34 patients (32.7%). The two groups were compared for age, genre, APACHE 2 and GCS. There was a significant difference in the ISS and TISS (p <0.001). Patients with pulmonary contusion had significantly lower PaO2/FiO2 ratio (240 [range, 160-380]) vs. 430 [range, 210-590]; p = 0.009); and significantly higher PaCO2 levels (43.5 mmHg [range, 38-52 mmHg] vs. 38 mmHg [range, 32-40 mmHg], p < 0.001). The number of cases of pneumothorax and hemothorax were significantly higher in the group of pulmonary contusion (p = 0.003, p = 0.021; respectively). Likewise, The occurrence of pneumonia and ARDS was significantly higher in the group of pulmonary contusion (p = 0.031, p = 0.023; respectively) with a shorter length of time between ICU admission and the occurrence of such complications; (6 days [range, 6-10 days]) vs. 13 days [range, 8-16 days]; p = 0.024) and (6 days [range, 2-8 days]) vs. 10 days [range, 8-10 days]; p = 0.016), respectively. No significant difference was observed with regard to the number of cases of shock (p = 0.174). The length of hospital stay was significantly higher in the group of pulmonary contusion (13.44 ± 6 days vs. 12.44 ± 4 days; p < 0.001). The overall mortality rate was 11.5% in pulmonary contusion group and 7.7% in the other group (Odds ratio, 4.22; 95% confidence interval, 1.527 to 11.703; p = 0.004).

Conclusion:

In this study, pulmonary contusion alters gas exchange and appears to increase the morbidity and mortality in patients with severe head trauma.


Snouda SALAH (Zaghouan, Tunisia), Hebaieb FATMA, Abbes MOHAMED FEHMI, Kaddour MOEZ, Ben Ghezala HASSEN
15:50 - 15:55 #11155 - Prognostic value of anatomic, physiologic and combined trauma scores to predict mortality.
Prognostic value of anatomic, physiologic and combined trauma scores to predict mortality.

Background: Trauma is a leading cause of mortality in young people aged under 40 years. Early assessment of prognosis is a cornerstone in the management of severe trauma. Several prognostic scores have been proposed in the literature during last decade. The aim of this study was to evaluate the prognostic value and to compare five trauma scores in terms of mortality at day 30 in severe trauma patients admitted to the emergency department.     

Methods: This was a prospective, observational study with inclusion of severe trauma admitted to the emergency department during a 20-month period. We focused on the predictive value of 5 specific trauma scores in terms of mortality in severe trauma admitted to the resuscitation room. Five scores were included: The Injury Severity Score (ISS), the New NISS, The Emergency Trauma Score (EMTRAS) and the GAP and M-GAP scores. Multivariate analysis of mortality at day 30 post-trauma was conducted with comparison of ROC curves.

Results: We included 298 patients. Median age was 40 (15-80) years. Sex ratio was 4,5. Clinical characteristics: n (%): GCS ≤ 8: 62 (21); PAS <90 mm Hg: 32 (11) and pulse oximetry <90%: 44 (15). The median ISS was 17 (0-75) and 176 (59%) trauma patients had a score ISS ≥ 16. The global mortality  was 21.5%. Independent predictors of mortality after multivariate analysis were respectively : EMTRAS score ≥ 3 (adjusted OR 1.80, 95% CI [1.05-3.08], p = 0.0033), ISS ≥ 16 (adjusted OR 2.05; 95% CI [1.26-3.46],p = 0.002),GAP <20 (adjusted OR 1.92, 95% CI [1.268-2.92], p = 0.002) 1.74, 95% CI [1.17-2.592], p = 0.005). After comparison of the 5 scoring tools, the GAP score showed the best AUC= 0.811 followed by the EMTRAS with an AUC of 0.789.

Conclusion:  Severe trauma is a dynamic process with high rate of morbidity and mortality. The need to an accurate evaluation of the prognosis remains a challenge for the emergency physician. Many scoring tools were proposed. In our study, all scores were able to predict mortality but physiological GAP score showed the higher AUC and so that could be proposed as safe to be used at the early stage for evaluation in the ED.


Hamed RYM (Tunis, Tunisia), Maaref AMEL, Ahmed SOUYAH, Bellili SARRA, Alaa ZAMMITI, Badra BAHRI, Wided DEROUICHE, Chokri HAMOUDA
15:55 - 16:00 #11606 - Lactate at admission versus Injury Severity Score in trauma patients for predicting mortality.
Lactate at admission versus Injury Severity Score in trauma patients for predicting mortality.

Introduction :

Early detection of at-risk trauma patients remains a challenge for emergency physicians and guides both triage and making decision. In this context, biological tools were proposed within the last decades such as lactate – rapidly available in the emergency department (ED) and widely correlated with severity and mortality. This study aimed to compare the lactate prognostic value in terms of early and delayed mortality with the anatomical Injury Severity Score (ISS), a reference score proposed worldwide in the litterature but obtained after completing explorations in trauma patients.

Methods:

It was a single-center prospective study (12 months). Inclusion of severe trauma patients over 18 years admitted to the emergency resuscitation room at the ED. Arterial lactate at admission was drawn on a point-of-care sample gaz before any resuscitation attempts. ISS were calculated after completed explorations and assessment. Mortality at day 7 and 30 was colliged with comparison of the ROC curve’s characteristics of both lactate and ISS towards mortality.

Results:

We enrolled 190 trauma patients with median age (min, max) = 34 years (18,85) and sex-ration= 4. Road traffic accident was the predominant cause of trauma in 140 cases (74%). Average ISS (SD)= 20 (12) with ISS >= 16 in 122 patients (22%). Mortality rate was respectively 26% at day-7 and 29,5% at day-30. Median lactate (IQR) =2,4 mmol/l (0,4- 10,9) and lactate >=2,5 mmol/l was found in 118 patients (62%). ISS and lactate were significantly higher in non-survivors than in survivors; p<0,001. Moreover, ISS was superior to lactate in predicting mortality. The ROC curves characteristics were respectively :  Mortality at Day-7  (ISS: AUC = 0,930; CI95% [0,895-0,964]; p<0,001) vs (Lactate: AUC =0,704; CI95% [0,622- 0,786]; p<0,001) and mortality at Day-30 ( ISS: AUC 0,951; CI95% [0,924- 0,978]; p<0,001) vs (lactate: AUC 0,700 ; CI95% [0,621-0,779]; p<0,001).

Conclusion :

In this study, indeed ISS remains a higher tool for predicting mortality but is difficult to calculate and is late to obtain with the need of exhaustive morphologic injury assessment. Lactate showed a good predictive value for both early and delayed mortality with strong significative AUC. Moreover, lactate is  rapidly available in few minutes after admission at the ED and so that can be proposed for early  accurate assessment in severe injured patients. Our study was single-center with a limitation of small size sample. Enlargement of the size and conducting multi-centric study in the future could improve sensitivity and predictive value of lactate biomarker.


Hamed RYM (Tunis, Tunisia), Aymen ZOUBLI, Hana HEDHLI, Alaa ZAMMITI, Badra BAHRI, Wided DEROUICHE, Héla BEN TURKIA, Chokri HAMOUDA
16:00 - 16:05 #11826 - Systematic review of interventional studies carried out in emergency medical call centres.
Systematic review of interventional studies carried out in emergency medical call centres.

Introduction

Methodological evaluation of interventional studies conducted via emergency medical call centres has not previously been performed.

Objective

To describe in both quantitative and qualitative terms interventional research performed in medical call centres.

Methods

Study: Systematic review.

Search engines: PubMed, World of Science, Cochrane Methodological Register, OMS Register and ClinicalTrials.

Inclusion criteria: Studies evaluating therapeutic or organisational interventions, directed by call centres, enacted by responding physicians, paramedical teams or bystanders, in the context of situations judged to be emergencies by callers.

Exclusion criteria: Studies focussed on call management for general practice or non-healthcare agencies.

Parameters collected: Delay to publication, general characteristics of the study, study population (patients, mannequin based training, experimental modelling), number of patients included, theme or pathology targeted by the study, primary and secondary outcome measure(s), funding, ethical approval, quality criteria evaluated according to the risk of bias scale (ROB) or the Newcastle-Ottawa scale (NOS). For NOS, scores of 0-3, 4-6, and 7-9 are regarded as low, moderate, and high quality respectively.

Methodology: Extraction of parameters by two independent investigators. In cases of disagreement, a third expert investigator was consulted.

Results

Our search terms yielded 3896 articles. After examining abstracts, 47 articles were retained. The median delay to publication was 36 weeks (IQR: 30-48). Thirty-three of the studies were clinical trials (70%) and 14 (30%) were before-after trials. Studies were monocentric in 33 (70%) of cases and 32 (70%) used randomisation. The models used were simulation training, patient based or experimental studies in 26 (55%), 17 (38%), and 3 (6%) of articles respectively. The median number of subjects included was 147 (IQR: 74-1271). The theme most commonly targeted was cardiac arrests (n=36, 77%), with outcome measures of CPR quality and dispatch assistance. Other themes included triage in the call centre, management of pathologies such as myocardial infarct, severe trauma, cerebrovascular accidents, and analysis of the transmission of information. Ethical committee approval was declared in 38 (81%) of cases. Funding was reported by 26 (55%) of studies. Among the randomised-trials, selective reporting was high for 24 (75%) studies, blinding of outcome was low for 28 (88%) and incomplete outcome was low for 23 (72%) studies. Regarding non-randomised studies, quality was high, intermediate and low respectively in 7 (50%), 6 (43%) and 1 (7%) of cases.

Conclusion

Few interventional studies have been carried out in call centres. Those that exist principally describe simulation studies, and often focus on cardiac arrest. The quality of studies needs improvement in order to allow a better recognition and understanding of emergency medical call control.


Paul-Georges REUTER (Rennes), Anthony CHAUVIN, Frédéric ADNET, Frédéric LAPOSTOLLE, Youri YORDANOV
E-Poster Area

"Tuesday 26 September"

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PH5 - S4
15:45 - 16:05

E-Poster Highlight Session 5 - Screen 4

15:45 - 15:50 #11008 - Sesamin Ameliorates Mucosal Tissue Injury of Mesenteric Ischemia and Reperfusion in an Experimental Rat Model.
Sesamin Ameliorates Mucosal Tissue Injury of Mesenteric Ischemia and Reperfusion in an Experimental Rat Model.

Introduction

Mesenteric ischemia/reperfusion (I/R) injury is a serious clinical condition. There were a lot of experimental studies performed in the treatment of I/R injury. In our knowledge, this is the first experimental study with effects of sesamin on I/R injury model. We aimed to investigate the protective effect of sesamine on mesenteric I/R injury model.

Materials and methods

A total of 32 male Sprague-Dawley rats were divided into four groups. Control group: superior mesenteric artery (SMA) exposed without clamping. I/R group: SMA was clamped for 60 minutes and then reperfused for 2 hours. Sesamin group (S): 30 mg/kg sesamin were given for 5 days, and SMA exposed without clamping. I/R+S group: 30 mg/kg sesamin were given for 5 days, SMA was clamped for 60 minutes and then reperfused for 2 hours. We studied plasma and tissue oxidant parameters and histopathological evaluation was performed.

Result

Plasma and tissue TAS levels were significantly higher in I/R+S group compared to the rest (p<0.005). The plasma TAS levels in I/R group was significantly low. The highest tissue TAS levels were detected in I/R+S group. The high levels of plasma and tissue TOS were found in I/R+S group. Plasma and tissue OSI levels were significantly higher in I/R group. Histopathologic evaluation showed that; the mean level of intestinal tissue injury score in I/R group was 2,75 and was 1.38 in I/R+S group. 

Conclusion

Sesamin helps to protect the intestinal tissue at the cellular level by reducing the oxidative stress and inflamation at both the plasma and tissue levels in the experimental I/R model.

 


Mustafa SAYHAN, Serhat OGUZ, Ömer SALT (EDIRNE, Turkey), Nuray CAN, Taner OZGURTAS, Tulin YALTA
15:50 - 15:55 #11193 - Emergency EEG: actual indications and clinical practice.
Emergency EEG: actual indications and clinical practice.

Introduction

Electroencephalography is regularly used in the emergency department, but its relevance and value are actually difficult to assess, despite clear guidelines from the Société de Neurophysiologie Clinique de la Langue Française (SNCLF). The purpose of this study was to evaluate the relevance of EEGs in the emergency department by comparing actual indications and clinical practice.

Method

Monocentric, retrospective study over a 6 months period, from 01/01/2014 to 31/06/2014 at the emergency department. The EEGs performed were classified as recommended and non-recommended, as regards to the guidelines from the SNCLF.

Results

476 EEGs were performed over this period. 389 were used for statistical analysis. Mean age was 62.6 +/- 20.3 years, with a sex ratio of 1.2 (M:F). 30.8% of EEGs were recommended. The clinical symptoms that led to an EEG were varied and often linked. We noted 57.5% of confusion and 50.8% for generalized tonic-clonic seizures in the recommended group. In the non-recommended group, 40.9% of EEGs were performed for funny turns and 28.3% for altered mental states. The recommended EEGs lead to the final diagnosis in 24.4% of the generalized tonic-clonic seizures and 6.2% of altered mental states. For the non-recommended group, rates were 4.8% and 9% for these clinical presentations. 19.2% of recommended EEGs had a therapeutic impact VS 5.9% for non-recommended. The duration of hospitalization was 4.54 days for the group of recommended EEG VS 8.45 days for the non-recommended.

Discussion

Our study demonstrates that the EEG has a greater diagnostic and therapeutic contribution when the guidelines of the SNCLF are followed. Concerning altered mental states, diagnostic value of the EEG is weak and almost equivalent in both groups. This suggests that EEGs should not be performed in this indication. Half of the hospital stay for patients with recommended EEG was also reduced.

Conclusions

Although the indications of the EEG in the emergency department are clearly established, its relevance remains uncertain. Indeed, our study shows that non-recommended EEGs are equivalent in diagnostic value regarding altered mental states, reaffirming the premise that any paraclinic examination should be requested after a thorough clinical examination. 


Amish SEERUTTUN (STRASBOURG), Hakim SLIMANI, Thibault DESMETTRE, Marianne-Claire LABOUREYRAS, Vinh Phuc LUU, Thibault SCHILLIG
15:55 - 16:00 #11466 - Potential of novel biomarkers in prehospital management of traumatic brain injury: the pre-tbi study.
Potential of novel biomarkers in prehospital management of traumatic brain injury: the pre-tbi study.

Background: Traumatic brain injury (TBI) is the leading cause of death and disability among young adults worldwide. Difficulties in clinical assessment and triage of TBI patients in the prehospital phase results in numerous precautionary hospital admissions of mild TBI patients and treatment delay due to mis-triage of moderate and severe TBI patients. Early knowledge on biomarker values is suggested key to improvement of patient outcome as it may guide clinical-decision-making already in the prehospital phase.

Aim: To investigate the potential of early biomarker measurements in prehospital management of TBI patients.

Methods: 3 Prospective, observational studies were designed to investigate ROC characteristics of S100B, GFAP and NSE in relation to clinically relevant endpoints. 690 adult patients suffering mild, moderate and severe TBI in Central Denmark Region will be included from February 15 2017 - June 15 2018. Blood samples are drawn in the ambulance, on admission and repeatedly during the first 12 hours past trauma. Blood samples are stores in a biological bank and batch analysis will be done after 6, 12 and 18 months during the period og inclusion. An endpoint adjutication comittee of senior researchers will review patient causes blinded to biomarker values in relation to endpoint of the relevant study:

PreTBI I:Diagnostic Potential of S100B and GFAP in Prehospital Rule-Out of Intracranial Lesions in Patients suffering Mild TBI.

PreTBI II:S100B and GFAP in Prehospital Prediction of Need for Neurosurgical Observation or Intervention in Patients suffering Moderate TBI.

PreTBI III: Prognostic Potential of S100B, GFAP and NSE in Patients suffering Severe TBI.

Perspectives: To underline the potential of prehospital biomarker measurements for effective rule-out of low risk patients and rule-in of high-risk patients in order to minimize treatment delay, secure optimal resource consumption and streamline patient courses for patients suffering neurotrauma. Ultimately to elucidate the need for development of a point-of-care analysis.


Sophie-Charlott SEIDENFADEN (Aarhus N, Denmark), Morten Thingemann BØTKER, Niels JUUL, Hans KIRKEGAARD, Ingunn Skogstad RIDDERVOLD
16:00 - 16:05 #11714 - Pediatric cardiac arrest: Is outcome related to the time of admission?
Pediatric cardiac arrest: Is outcome related to the time of admission?

Background and Objectives: Nights and weekends represent a potentially high-risk time for pediatric cardiac arrest (CA) patients in emergency departments (EDs). Data regarding night or weekend arrest and its impact on outcomes is controversial. This study performed to determine the relationship between cardiopulmonary resuscitation (CPR) during the various ED shifts and survival to discharge.

Methods: We conducted a retrospective, observational study in which patients who had visited our ED for cardiac arrest from January, 2013 to December 2015. We examined survival from cardiac arrest in hourly time segments, defining within working hours as 8:00 AM to 17:00 PM, out of working hours as 17:00 PM to 7:59 AM and weekend as 17:00 PM on Friday to 7:59 AM on Monday. Medical records and patient characteristics of 54 children with cardiac arrest were retrieved from patient admission files.

Results: The median age was 3 years, 59% were male and 17 patients were younger than 12 months. A total of 26 cases of cardiac arrest admitted at working hours to ED and 28 cases admitted at out of working hours. Rates of survival to discharge 30.8% (n=8) within working hours vs out of working hours 3.6% (n=1). Among in cardiac arrests presenting to ED, survival was higher on working hours than out of working hours (p=0.01). Rate of return of spontaneous circulation within working hours was higher than out of working hours (54% vs.18%) (p=0.009).  Patients older than 5 years had poor outcome, whereas better outcome was associated with in-hospital cardiac arrest (p<0.05). The first documented rhythm at our group was more frequently to be asystole (92%).

Conclusion: Survival rates from pediatric cardiac arrest are lower during out of working hours.  The outcome has also been related to duration of CPR, age and location of CA.


Eylem Ulas SAZ (IZMIR, Turkey), Dr Ali YURTSEVEN, Caner TURAN
E-Poster Area

"Tuesday 26 September"

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PH5 - S5
15:45 - 16:05

E-Poster Highlight Session 5 - Screen 5

15:45 - 15:50 #9948 - Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia.
Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia.

Purpose: Hydroquinone (HQ), a major metabolite of benzene, exists in many plant-derived food and products. Although many studies have addressed biological properties of HQ including the regulation of immune responses and antioxidant activity, neuroprotective effects of HQ following ischemic insults have not yet been considered. Therefore, in this study, we examined neuroprotective effects of HQ against ischemic damage in the gerbil hippocampal cornu ammonis 1 (CA1) region following 5 min of transient cerebral ischemia.

Methods: To elucidate the neuroprotective effects of HQ against ischemic damage, the gerbils were divided into 8 groups (n = 7 in each group), as follows: 1) vehicle-treated sham-operated group (vehicle-sham-group), 2) vehicle-treated ischemia-operated groups (vehicle-ischemia-group), 3) and 4) 50 and 100 mg/kg HQ-pre-treated sham-operated groups (pre-HQ-sham-groups), 5) and 6) 50 and 100 mg/kg HQ-post-treated sham-operated groups (post-HQ-sham-groups) 7 and 8) 50 and 100 mg/kg HQ-pretreated ischemia-operated groups (pre-HQ-ischemia-groups), 9 and 10) 50 and 100 mg/kg HQ-post-treated ischemia-operated groups (post-HQ-ischemia-groups). HQ was purchased from Sigma (St. Louis, MO, USA) and dissolved in saline. For pre- and post-treatment, HQ or saline was intraperitoneally administered once at 30 min before or after ischemic surgery, respectively. Sham-operated animals were subjected to the same surgical procedures except that the common carotid arteries were not occluded.

Results: We found that pre- and post-treatments with 50 and 100 mg/kg of HQ protected CA1 pyramidal neurons from ischemic insult. Especially, pre- and post-treatments with 100 mg/kg of HQ showed strong neuroprotective effects against ischemic damage. In addition, pre- and post-treatments with 100 mg/kg of HQ significantly attenuated activations of astrocytes and microglia in the ischemic CA1 region compared to the vehicle-treated-ischemia-operated group.

Conclusion: Briefly, these results show that pre- and post-treatments with HQ can protect neurons from transient cerebral ischemia and strongly attenuate ischemia-induced glial activation in the hippocampal CA1 region, and indicate that HQ can be used for both prevention and therapy of ischemic injury.


Jun Hwi CHO, Joong Bum MOON, Myoung Chul SHIN (Chuncheonsi, Republic of Korea), Taek Geun OHK, Chan Woo PARK, Moo Ho WON
15:50 - 15:55 #11095 - Applying a modified time-driven activity based costing method to emergency department care in Sweden.
Applying a modified time-driven activity based costing method to emergency department care in Sweden.

Background Costs of healthcare services are difficult to determine. Accurately allocating costs of healthcare services to activities would enable better policy decisions on subjects such as optimal care venues, spending priorities, and staffing. Current cost-per-patient systems (kostnad-per-patient, KPP) consolidate Emergency Department costs for some patient encounters with inpatient costs, obscuring the true costs of ED care. Standard cost accounting allocates all costs to current patients, creating the appearance of cost increases with decreased utilization. We developed the Patient Encounter Cost (PEC), a method for more accurately assigning costs within a regional emergency department (ED) care system to account for excess capacity.

Methods We used data from Region Halland, Sweden, a county of 300,000 people over 5,500 km2. We analyzed 2015 records of the entire population of 88,132 ED visits across 2 ED sites in the region.  We calculated total costs incurred of 212 million Swedish Crowns (SEK), or approximately 25 million USD. Time spent per visit was determined from prospectively recorded ED records and adjusted by published weighting factors for nursing care by triage acuity level. Total capacity was determined based on available nursing and physician staff time. We developed the PEC using time-driven activity based costing (TDABC) methods to determine unit-time costs for ED care. Unit-time costs were then used to determine total ED patient-care costs for the year 2015.

Results In 2015, Region Halland spent 212 million SEK on its emergency departments, incurring unit costs of 1,787 SEK per nursing hour. The average ED visit service cost 2,363 SEK (95%CI 2,273-2,453), ranging from 460 SEK (454-466 SEK) for triage level 5 patients to 4,507 SEK (4,505-4,509 SEK) for triage level 1 patients. Total costs spent on direct patient care accounted for 191 million SEK, showing a utilization of 81% of available capacity. The average ED visit service cost 2,363 SEK using PEC techniques compared to 2,865 SEK using traditional health care cost accounting techniques.

Conclusion PEC can be used to allocate costs down to the individual patient encounter level within a regional emergency care system using readily-available data. This method has the potential to contribute to policy decisions regarding appropriate excess capacity and allocation of scarce healthcare resources, as well as more closely aligning costs with prices in systems without a single payer. Next steps include refining the model for greater granularity of cost assignment to patient care visits.


Jonathan SLUTZMAN, Zayed YASIN (Boston, USA), Jonny ERIKSSON, Jonas HULTGREN, Philip ANDERSON
15:55 - 16:00 #11593 - Can Serum S100B be a predictor of neuronal damage and clinical poor outcomes associated with the use of synthetic cannabinoids?
Can Serum S100B be a predictor of neuronal damage and clinical poor outcomes associated with the use of synthetic cannabinoids?

Background: There has been an increasing number of emergency department visits due to synthetic cannabinoid use. There is little information about the structural and functional damage caused by the use of synthetic cannabinoids. This study aims to evaluate the serum S100B levels to predict neuronal damage and clinical poor outcomes associated with the use of synthetic cannabinoids.

Method: Thirty patients with synthetic cannabinoid user and 30 healthy controls were included in the study. The S100B levels were measured with a Human ELISA kit. Serum S100B levels were compared to healthy controls with synthetic cannabinoid users. Among the users of synthetic cannabinoids, patients with the following outcomes were considered to have a composite outcome: the need for endotracheal intubation due to hypoventilation and decreased GCS; seizures; the need for intensive care unit admission; and in-hospital mortality. Clinical and laboratory findings associated with composite clinical outcomes were examined.

Results: We found significantly increased S100B levels in patients with synthetic cannabinoid use. The mean serum S100B level was 19.32 ± 4.92 pg/mL in patients with synthetic Cannabinoid user, and 15.94 ± 2.43 pg/mL in the control group (p = 0.001).  In patients with and without composite clinical outcomes, the mean serum S100B level was measured as 24.13 ± 5.48 pg/mL, and 17.58 ± 3.38 pg/mL, respectively (p = 0.001). With the cut-off value for S100B set at 20 pg/mL based on the highest sensitivity; the sensitivity, specificity, positive predictive value, and negative predictive value for S100B were 89.9%, 52.0%, 44.4% and 91.9%, respectively.

Conclusion: Our data suggest that serum S100B levels are elevated in patients using synthetic cannabinoids. But the role of high S100B level in determining neuronal damage and clinical poor outcomes was limited. These results show that S100B can help clinicians to exclude neuronal damage and possible poor outcomes. 


Yilmaz SERKAN (İstanbul, Turkey), Karakayalı ONUR, Kale EBRU, Akdogan AHMET
16:00 - 16:05 #11467 - Traumatic brain injury - how do we dispatch ?
Traumatic brain injury - how do we dispatch ?

Background: Severe traumatic brain injury (TBI) is considered a time-critical condition. Relevant emergency medical response must be commenced, which makes dispatch key. Danish ambulance dispatch is criteria-based depending on main symptom or incident, but no separate dispatch criteria exist for head trauma or suspected TBI. Dispatch are graded level A to E according to severity of emergency call.

Aim: To investigate which dispatch criteria are assigned patients with severe TBI (confirmed intracranial lesion), if the highest level (A) of emergency response are commenced and to examine related 30-day mortality.

Methods: Population-based follow-up study of emergency medical calls in the Central Denmark Region from October 1 2011 - December 31 2014 concerning patients subsequently diagnosed with severe TBI according to ICD-10 codes from Danish National Patient Registry. For patients with confirmed intracranial lesion odds of receiving the highest level of emergency response was investigated in a logistic regression model.

Results: Of 76,009 emergency medical calls, 1382 patients were subsequently diagnosed with TBI (1.8%) of which 216 patients suffered severe TBI with intracranial lesion. Patients were assigned 14 different dispatch criteria. Level of emergency response was dependent on assigned dispatch criteria: 11 of the 216 severe TBI patients were assigned the lowest level of emergency response (telemedical advice). 30-day mortality was 1.5% (95% CI 1.0-2.0%) for overall TBI and 8.8% (95% CI 5.7-13.3%) in severe TBI.

Conclusion: Severe TBI patients are assigned different dispatch criteria. Highest level of emergency response varies within subgroups of dispatch criteria. Patients suffering intracranial lesions have a high 30-day mortality.


Sophie-Charlott SEIDENFADEN (Aarhus N, Denmark), Ingunn Skogstad RIDDERVOLD, Niels JUUL, Hans KIRKEGAARD, Morten Thingemann BØTKER
E-Poster Area
16:10

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A34
16:10 - 17:40

Neurological (Cutting Edge)

Moderators: Dr David CARR (Associate Professor of Emergency Medicine) (Toronto Canada, Canada), Pr Jim DUCHARME (Immediate Past President) (Mississauga, Canada)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
16:10 - 16:40 TIA. Jeff PERRY (Physician) (Speaker, Ottawa, Canada)
16:40 - 17:10 Thunderclap headache - not just an SAH. Pr Jim DUCHARME (Immediate Past President) (Speaker, Mississauga, Canada)
17:10 - 17:40 Turning a zebra into a horse. Dr David CARR (Associate Professor of Emergency Medicine) (Speaker, Toronto Canada, Canada)
Trianti Hall

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B34
16:10 - 17:40

Infectious Disease & Sepsis (How To)

Moderators: Christoph DODT (Head of the Department) (München, Germany), Marc SABBE (Medical staff member) (Leuven, Belgium)
Coordinator: Christoph DODT (Coordinator, München, Germany)
16:10 - 16:40 Sepsis treatment: in the ED or ICU? Christoph DODT (Head of the Department) (Speaker, München, Germany)
16:40 - 17:10 Evaluation of the effect of improved qSOFA score on the severity and prognosis of emergency adult sepsis patients. Cao YU (emergency) (Speaker, Chengdu, China)
17:10 - 17:40 Ultrasound in the ED in patients with sepsis. Cornelia HÄRTEL (Medical Director of the ED, Consultant in EM, Director of Medical Education in EM) (Speaker, STOCKHOLM, Sweden)
Mitropoulos

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C34
16:10 - 17:40

Work-life balance (The Boss' Office)

Moderators: Pr Pinchas HALPERN (department chair) (Tel Aviv, Israel, Israel), Katrin HRUSKA (Emergency Physician) (Stockholm, Sweden)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
16:10 - 16:40 The myth of gender gaps in EM. Adela GOLEA (Associate Professor) (Speaker, Cluj Napoca, Romania)
16:40 - 17:10 Physician, Parent, Ironman: How to Have it All. Gayle GALLETTA (Emergency medicine physician) (Speaker, USA/Norway, USA)
17:10 - 17:40 The challenge to be the man in the ED. Robert LEACH (Head of Dept.) (Speaker, BRUXELLES, Belgium)
Banqueting Hall

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D34
16:10 - 17:40

YEMD - Simulation

Moderators: Dr Anastasia SFAKIOTAKI (Emergency Physician) (Melbourne, Australia), Jennifer TRUCHOT (MEDECIN) (Paris, France)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
16:10 - 16:40 Building simulation "on the cheap": full scale simulation for less than 10.000€. Mohammed MOUHAOUI (Professeur) (Speaker, Casablanca, Morocco)
16:40 - 17:10 Research in simulation: 2017 update. Luca CARENZO (SIMULATION COMPETITION ONLY) (Speaker, NOVARA, Italy)
17:10 - 17:40 Communication in a crisis: how to become a confident (young) team leader. Jennifer TRUCHOT (MEDECIN) (Speaker, Paris, France)
Skalkotas

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E34
16:10 - 17:40

Nursing session 4

Moderators: Sivera BERBEN (research coordinator) (Nijmegen, The Netherlands), Door LAUWAERT (Manager) (BRUSSELS, Belgium)
16:10 - 16:40 BLS/AED training of deaf and hard-hearing citizens under the ERC guidelines. Tzannis POLYKANDRIOTIS (Speaker, Greece)
16:40 - 17:10 Managing delirium in the ED. Thomas DREHER-HUMMEL (Nurse) (Speaker, Basel, Switzerland)
17:10 - 17:40 EARLY WARNING SCORE-The need for inclusion in Greek hospitals. Stamatina IORDANOPOULOU (Speaker, Greece)
MC-3

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F34
16:10 - 17:40

Free Papers Session 11

Moderators: Pr Cem OKTAY (FACULTY) (ANTALYA, Turkey), Pr Riccardo PINI (Director, E.D. High Dependency Unit) (Florence, Italy)
16:10 - 16:20 #10843 - OP091 Diagnostic Value of New Sepsis Criteria in the Emergency Department (DISC study).
Diagnostic Value of New Sepsis Criteria in the Emergency Department (DISC study).

In February 2016 a new definition of the sepsis was introduced, redefining sepsis as a life-threatening organ dysfunction caused by a dysregulated host response to infection (.Sepsis-3). A shortened sequential Sepsis-related Organ Failure Assessment score (Q- SOFA score) is used to identify sepsis according to Sepsis-3 criteria. However, these new criteria have not yet been validated in a general emergency department (ED) patient population.

Methods

This is a multi-center, non-interventional observational pilotstudy. During this pilotstudy all adult patients who visit the ED with a suspected or proven systemic infection were included. In all included patients the SIRS criteria and the qSOFA criteria were collected. In addition to routine diagnostic tests such as blood cultures, the PCT levels will be determined.

Results from the first 100 inclusions

In this pilot of 100 patients 61 were male. Median age was 65.5 years (range 18 to 94). The q-SOFA was positive in 4 patients, while SIRS was positive in 44. The mortality in the total study population was 6%. 5 critically ill patients were not identified by qSOFA, while SIRS missed 2. 2 of the SIRS positive patients and none of the qSOFA positive patients were admitted to the intensive care unit. 

Conclusion

This pilot study showed the implementation of q-SOFA as a screening tool in suspected systemic infection, did not identify all patients who needed intensive care or those with bad outcome after visiting an emergency department. More research needs to be done in a larger study to compare validity and usefulness of this scores in the ED population.


Kaoutar AZIJLI (Amsterdam, The Netherlands), Tanca MINDERHOUD, Nicole HES, Rishi NANNA PANDAY, Susanne GIJSBERG, Nieke MULLAART, Tom BOEIJE, Bas HUISMAN, Prabath NANAYAKKARA
16:20 - 16:30 #11022 - OP092 Predictive factors of mortality in patients admitted to the emergency department for sepsis.
Predictive factors of mortality in patients admitted to the emergency department for sepsis.

Introduction: Despite major efforts to identify and treat sepsis early, this disease remains a major cause of mortality in hospitalized patients in the emergency department (ED).

Objective: To identify factors associated with intra-hospital mortality in patients admitted to ED for sepsis.

Methods: Prospective, observational, monocentric study, over 12 months in ED. Inclusion: patients (age ≥ 18 years) with a suspected infection associated with two or more criteria of the systemic inflammatory response syndrome (temperature ≥ 38 ° or ≤ 36 °C, heart rate> 90 bpm, respiratory rate> 20 / min, or Blood pressure in CO2 <32 mmHg or White blood cells> 12,000 cel / mm3, or <4,000 / mm3). Epidemiological, clinical, therapeutic and outcome criteria were collected. APACHE 2, SOFA and quickSOFA (qSOFA) scores were calculated. Prognosis was evaluated in intra-hospital mortality. Multivariate regression analysis to identify factors associated with mortality was performed.

Results: Inclusion of 185 patients (169 in sepsis and 16 in septic shock). Mean age = 61 ± 17 years. Sex ratio = 0.46. Comorbidities n (%): diabetes 88 (48), hypertension 87 (47), dyslipidemia 23 (12), chronic obstructive pulmonary disease 14 (7). Clinical manifestations (%): fever (76), altered general state (41), respiratory signs (39), digestive signs (35), neurological signs (9). Site of Infection (%): renal (39), pulmonary (30), cutaneous (15), digestive (12). Organ failure (%): renal (20), cardiac (15), respiratory (12), hepatic (8) and haematological (7) events. Median APACHE 2 score = 9. Median SOFA score = 6. Median qSOFA score = 1.Intra-hospital mortality = 5%.  

In adjusted multiple regression models, age >75 years (adjusted OR = 2.8, 95% CI [1.72- 3,25], p<0.001), renal failure (adjusted OR = 4.6, 95% CI [1.4-14.6], p=0.009), septic shock (adjusted OR= 2.7, 95% CI [1.9 -8.32], p=0.05), and HCO3- level<18mmol/l (adjusted OR= 2.9, 95% CI [1.1-7.6], p=0.03) were independently associated with intra-hospital mortality. 

Conclusion: In this study, age of 75 years, HCO3- level <18 mmol /, renal failure and septic shock were predictive factors for in-hospital mortality for patients admitted to ED for sepsis.

 


Hanen GHAZALI (Ben Arous, Tunisia), Soumaya MAHDHAOUI, Ines CHERMITI, Aymen ZOUBLI, Ihsen HNEN, Sawsen CHIBOUB, Mohamed MGUIDICH, Sami SOUISSI
16:30 - 16:40 #11113 - OP093 Using Support Vector Machine to develop of a Mortality Prediction Model for Septic Patients in the Emergency Department.
Using Support Vector Machine to develop of a Mortality Prediction Model for Septic Patients in the Emergency Department.

Background: Many studies in the past have reported that sepsis is one of the leading causes of mortality in hospitalized patients. However, information regarding factors for early predictive mortality is limited.

Objective: The aim of this present study was to develop a 28-day mortality prediction model and assess the validity of it for the septic patient population in the emergency department by a machine-learning algorithm, Support Vector Machine and to compare with the Sequential Organ Failure Assessment (SOFA) Score.

Methods: This prospective observational study conducted in the emergency department in the Chang Gung Memorial Hospital in Linkou. Consecutive patients meeting the criteria for sepsis during the first 24 hours of ED admission were included. The 28-day mortality collected prospectively by inpatient database or telephone follow-up. We made use of the demographic and laboratory variables that used to diagnosis sepsis as the candidate variables, and applied the recursive feature elimination method to select the significant ones to build the prediction models. Data were divided into training (75%) and testing (25%) sets, and repeated 30 times to avoid selection bias. To assess the performance of the build prediction model, we calculated the area under the Receiver Operating Characteristic curve (AUC), sensitivity, specificity, and accuracy for either individual variable but also the combination of selected variables.

Results: 379 patients were prospectively recruited from the emergency department with sepsis (SIRS and infection, 42.22%), severe sepsis (or Sepsis 3.0, 56.2%), and septic shock (1.58%) with a 28-day mortality rate of 10.03%. The selected variables for prediction model were respiratory rate, albumin, C-reactive protein, D-dimer, and fibrin-degradation products. The analysis results summarized in Table illustrates that the method of Support Vector Machine had promising performance of accuracy, specificity, and AUC in training (0.842, 0.853, and 0.879, respectively) and testing (0.821, 0.890, and 0.754, respectively) sets where better than SOFA score (AUC: 0.711, accuracy: 0.835).

Conclusion: Our results revealed that using the combination of several laboratory variables is promising for early prediction of mortality in sepsis. However, further efforts still need to improve and increase the reliability of early predict mortality of sepsis such as the technique of machine learning.


Pr Kuan-Fu CHEN (Taipei, Taiwan), Chin-Chien WU
16:40 - 16:50 #11147 - OP094 Eosinopenia: an interesting biological marker for the diagnosis of different infections in the ED.
Eosinopenia: an interesting biological marker for the diagnosis of different infections in the ED.

Introduction: The relevance of eosinopenia, as marker of infection, has been described in internal medicine, intensive care, and more recently in Emergency Departement (ED), for all infections combined. We aimed to specify the contribution of this biomarker in different common infections in ED, alone or in association with other inflammatory markers.

Methods: We present here a retrospective mono-centric study carried out in the Emergency Department of a teaching hospital in France for a  6 months period (September 2015-February 2016). All patients with one of the following diagnosis were eligible: appendicitis, cholecystitis, sigmoiditis, acute pyelonephritis, male urinary tract infection, pneumonia. Uninfected patients were randomly selected to form a control group of equivalent size to the cohort of infected patients collected for the study.

Results: We included a total of 466 infected patients and 466 controls. The sex-ratio in the infected group was 0.94, the mean age was 57.9 years (SD: 24.7 years). The eosinophil count in the infected patients was significantly reduced compared to controls (59/mm3 versus 129/ mm3, p <0.001). Deep eosinopenia (3) had a specificity of 94.4% for the diagnosis of infection (all combined) with a positive likelihood ratio (LR +) of 6.3 and an area under the curve (AUC ) of 75.9%. Eosinopenia was more effective in pyelonephritis, male urinary tract infections and acute cholecystitis (AUC > 80%), but had lower diagnostic performance in pneumonia (AUC =75%), appendicitis or sigmoiditis (AUC < 70%). The AUC of eosinopenia was higher than those of leucoccytosis in pyelonephritis and cholecystis. The association of eosinopenia with an increase of C-reactive Protein (> 40mg/l) or simply with the presence of fever (Temperature >38.5 ° C) showed a specificity greater than 99% and an LR + of 61 and 45 respectively.

Conclusion:  Eosinopenia is an interesting biological marker to consider in the ED, alone or in combination with other clinical or biological parameters in order to diagnose an infection. It is particularly interesting in urinary or biliary infections in which it is a better marker than leukocytosis.


Charles-Eric LAVOIGNET, Joffrey BIDOIRE, Sylvie CHABRIER, Sarah UGÉ (Strasbourg), Mickaël FORATO, Fanny SCHWEITZER, Pierrick LE BORGNE, Pascal BILBAULT
16:50 - 17:00 #11383 - OP095 Validation of qSOFA in the emergency department - a prospective study.
Validation of qSOFA in the emergency department - a prospective study.

Background

Sepsis is the primary cause of death from infection worldwide. Recently, the 2016 Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) defined sepsis as “life-threatening organ dysfunction caused by a dysregulated host response to infection.” Together with the updated definition of sepsis, a new clinical concept termed ‘Quick Sepsis-Related Organ Failure Assessment’ (qSOFA) was introduced to identify high-risk patients with suspected infection outside of intensive care settings. The previous criteria- Systemic Inflammatory Response Syndrome (SIRS) - were removed from the current sepsis definition. qSOFA has not been validated in Hong Kong (HK). In the current study, we aimed to validate qSOFA in an emergency department in HK. Furthermore, we sought to compare the prognostic value of qSOFA and SIRS as well as another commonly used early warning score, the National Early Warning Score (NEWS).

 

Methods

This is a single-centre, prospective study conducted in the ED of Prince of Wales Hospital, HK between Jul 2016 and Feb 2017. 665 patients presenting to the ED triaged as category 2 (Emergency) and 3 (Urgent) were recruited. All variables for calculating qSOFA, SIRS and NEWS were collected. The outcome measure was 30-day mortality. Venous lactate was also measured to investigate whether lactate level provide additional value for the prediction of 30-day mortality. The prognostic value of qSOFA, SIRS and NEWS to predict 30-day mortality was studied. Receiver Operating Characteristic analysis were performed to determine the Area Under the Curve (AUC), sensitivity, specificity, positive and negative predictive value, positive and negative likelihood ratio for qSOFA≥2, SIRS≥2 and NEWS>5.

 

Results

Of 665 patients recruited, median age was 73 years (IQR: 58-84); 313 (47%) were male. Overall 30-day mortality was 4.8%. The prognostic value for prediction of 30-day mortality, with AUC of for qSOFA≥2, SIRS≥2 and NEWS>5 were 0.54 (95%CI 0.51-0.58), 0.65 (95%CI 0.61-0.69) and 0.65 (95%CI 0.61-0.68) respectively. Using pairwise comparison of ROC curves, the difference between NEWS>5 and qSOFA≥2 in predicting 30-day mortality in ED patients was significant (p=0.0168). The AUC of lactate level ≥ 2 mmol/l of predicting 30-day mortality was 0.66 (95%CI 0.62-0.69). The combination of lactate level ≥ 2 mmol/l with qSOFA≥2, SIRS≥2 and NEWS>5, AUC were 0.53 (95%CI 0.49-0.57), 0.65 (95%CI 0.61-0.69) and 0.60 (95%CI 0.56 to 0.64) respectively. In addition, positive likelihood ratio of qSOFA≥2, SIRS≥2 and NEWS>5 to predict 30-day mortality were 19.69 (95%CI 4.14-93.73), 2.53 (95%CI 1.73-3.70) and 3.55 (95%CI 2.22-5.70).

 

Discussion

Among emergency and urgent patients presenting to the ED, the prognostic value for using NEWS was greater than qSOFA, while there was no difference between qSOFA and SIRS. Combinations of lactate level with qSOFA, SIRS or NEWS did not improve the prognostic value in predicting 30-day mortality for ED patients.


Ling Yan LEUNG, Dr Kevin Kei Ching HUNG (Hong Kong, Hong Kong), Ronson Sze Long LO, Yuk Ki LEUNG, Catherine Siu King CHEUNG, Chun Yu YEUNG, Suet Yi CHAN, Colin GRAHAM
17:00 - 17:10 #11486 - OP096 Early lactate clearance and short-term mortality in severe sepsis and septic shock patients.
Early lactate clearance and short-term mortality in severe sepsis and septic shock patients.

Introduction: The sensitivity and specificity of single lactate concentrations as markers of tissue hypoperfusion in sepsis have been debated. However, serial measurements or lactate clearance over time may be better prognosticators of organ failure and mortality.

Objective: Examine the clinical utility of the lactate clearance (or the percent decrease in lactate) as early as after 6 hours as an indicator of outcome in severe sepsis and septic shock.

Methods: Prospective observational study over one year. Inclusion of adult patients presenting to the emergency department (ED) with severe sepsis or septic shock. Inclusion criteria consisted of a suspected sepsis source and the following: a) two or more criteria of the systemic inflammatory response syndrome (SIRS) (temperature ≥38 ° C or ≤36 ° C, heart rate> 90 beats/min, respiratory rate > 20 / min or PaCO2 <32 mm Hg or WBC > 12,000 cel / mm3 or <4,000 / mm3) associated with organ failure (defining severe sepsis) or b) two of the SIRS criteria and a persistent hypotension (SBP <90 mmHg) despite fluid resuscitation or signs of hypoperfusion (lactate ≥4 mmol / l) (defining septic shock). Serial lactate levels in ED admission and 6 hours (h) later were measured. Lactate clearance, percent decrease in lactate level in 6 h ((lactate admission – lactate 6 h) x 100/lactate admission) was calculated. The main outcome measure was 7-day mortality.

Results: Inclusion of 253 patients. Mean age was 61 ± 17 years. Sex-ratio = 0.84. The overall mortality at the seven day was 10%. Baseline APACHE II score was 12 ± 78 and the median admission lactate was 1.1 mmol/L [0.6, 2.27]. Survivors compared with nonsurvivors had a median lactate clearance of 25 vs. 19, respectively (p=0.05). Based on Area Under the Curve in receiver operating characteristic analysis, lactate clearance have a significant inverse relationship with short-term mortality (0.63, 95% CI [0.45 to 0.80]), with a cut-off at 25%. The sensitivity, specificity, positive predictive value and negative predictive value of this cut-off were   56, 47, 25 and 81% respectively.

Conclusions: Lactate clearance in the most proximal presentation of severe sepsis and septic shock is associated with improved mortality rates. This is consistent with current efforts that emphasize the importance of identifying and treating tissue hypoperfusion during the first 6 hours of resuscitation. 


Hanen GHAZALI (Ben Arous, Tunisia), Ihsen HNEN, Soumaya MAHDHAOUI, Ines CHERMITI, Aymen ZOUBLI, Ahlem AZOUZI, Sawsen CHIBOUB, Sami SOUISSI
17:10 - 17:20 #11543 - OP097 An e-learning program to attempt to decrease the use of Third-generation cephalosporin for pneumonia in the Emergency Department.
An e-learning program to attempt to decrease the use of Third-generation cephalosporin for pneumonia in the Emergency Department.

Background: Third-generation cephalosporins are particularly prone to promote bacterial resistance. Their use for pneumonia increased between 2002 and 2012 in our Emergency Department, and 80% of these prescriptions may have been avoided, i.e. third-generation cephalosporin may have been replaced by a penicillin. In 2013, we implemented an e-learning program that encouraged treating pneumonia with a penicillin rather than a Third-generation cephalosporin, when possible. The e-learning was completed by 65% of physicians in 2013 and by every Emergency Department resident since 2013. 

Objectives: to assess if the e-learning implementation was associated with a decreased proportion of patients treated with a Third-generation cephalosporin and with a decreased proportion of avoidable Third-generation cephalosporin prescriptions.

Methods: Retrospective study of a random sample of patients treated for community-acquired pneumonia in an emergency department between 2002 and 2015, and subsequently hospitalized in non-Intensive Care Units. Third-generation cephalosporin prescriptions were presumed unavoidable if they met both criteria: (i) age ≥ 65 year’s old or a comorbid condition; and (ii) allergy or intolerance to penicillin, or failure of penicillin first-line therapy, or treatment with penicillin in three previous months. Prescriptions were otherwise deemed avoidable. Percentages are shown with 95% confidence interval.

Results: 956 patients were included. The proportion of patients treated with a Third-generation cephalosporin increased significantly from 14% [7%–24%] in 2002 to 30% [20% – 42%] in 2012 (Chi-scare for trend, P=0,02). This proportion was stable between 2013 (26% [18%-36%]) and 2015 (29% [19%-40%]; Chi-scare for trend, P=0,78). Treatment with a Third-generation cephalosporin was avoidable in 165 out of 212 patients (78% [72% – 84%]) during the whole study period. The proportion of avoidable prescriptions tended to decrease after the e-learning implementation, but the difference was not statistically significant (before e-learning, 79% [72%– 85%]; after e-learning, 74 % [62% – 84%]; P=0,6). 

Conclusion: The implementation of an e-learning program seemed to stop the yearly increase of the proportion of patients treated with a Third-generation cephalosporin for pneumonia in the Emergency Department, but it failed to decrease the proportion of avoidable prescriptions of Third-generation cephalosporin. Other interventions are necessary to decrease the use of Third-generation cephalosporin for pneumonia in the Emergency Department.


Nicolas GOFFINET (Nantes), Loan THUONG, François JAVAUDIN, Emmanuel MONTASSIER, Philippe LE CONTE, Eric BATARD
17:20 - 17:30 #11576 - OP098 QuickSOFA is an independent predictor of 30-day mortality among patients admitted to an emergency department with suspected or documented infection.
QuickSOFA is an independent predictor of 30-day mortality among patients admitted to an emergency department with suspected or documented infection.

QuickSOFA is an independent predictor of 30-day mortality among patients admitted to an emergency department with suspected or documented infection

Osama Bin Abdullah1, Johannes Grand1, Astha Sijapati1, Petrine Nimskov1 , Finn Erland Nielsen1,2
1. Department of Emergency Medicine, Slagelse Hospital, Slagelse, DENMARK
2. Institute of Regional Health Services Research, University of Southern Denmark, DENMARK.

Background. Definitions and clinical criteria for sepsis have been revised in 2016. A simple bedside score (‘qSOFA’, for quick Sequential [Sepsis-Related] Organ Failure Assessment) has been proposed, which incorporates hypotension (systolic blood pressure ≤100mmHg), altered mental status and respiratory rate ≥ 22/min: the presence of at least two of these criteria has been associated with poor outcomes typical of sepsis.

Purpose. To evaluate qSOFA as a predictor of 30-day mortality in a model with other predictors of death among patients admitted to a single-centre emergency department (ED) with either suspected or documented infection on admission.

Methods. A historical cohort study among prospectively registered patients with suspected or documented infection. The patients were having at least two Systemic Inflammatory Response Syndrome (SIRS) criteria on admission and all the patients were treated with intravenous antibiotics in the ED. The admission period was from 1 November 2013 to 31 October 2014. Baseline clinical data and data for survival were obtained from a standard sepsis admission form, the patient records and The Danish Civil Registration System. Logistic regression analysis was used to adjust for potential confounders and to determine whether the predictive factors for death in the crude analyses were independently associated with 30-day mortality.

Results. A total of 434 patients with a median age of 70 years were included in the study, 246 (56.7%) were men. Fifty seven (13.1%; 95% confidence interval [CI] 9.9-16.3%) patients died during the first 30 days. Among several potential confounders tested in the model we found that age (odds ratio [OR] 1.29; 95% CI 1.03-1.61), Charlson Comorbidity Score ≥ 3 (OR 3.83; 95% CI 1.41-10.37), qSOFA score ≥2 (OR 4.78; 95% CI 2.09-10.91) and lactate values (lactate values < 2.0 as reference) in the interval 2.00-3.99 (OR 2.21; 95% CI 1.06-4.62) and lactate values ≥ 4.0 (OR 3.97; 95% CI 1.44-2,92) were associated with 30-day mortality.

Conclusion. This study shows that a new simple clinical bedside index, qSOFA, can be helpful to identify infectious patients in an ED with an increased risk of 30-day mortality.


Dr Osama Bin ABDULLAH (Copenhagen, Denmark), Johannes GRAND, Astha SIJAPATI, Petrine NIMSKOV, Finn Erland NIELSEN
17:30 - 17:40 #11719 - OP099 A predictive score of acute appendicitis for practice in emergency department.
A predictive score of acute appendicitis for practice in emergency department.

Introduction :

Acute appendicitis is the most surgical emergency. Its diagnosis is not already evident. So we need a predictive score as simple and effective  to avoid  unnecessary investigations.Objective :To establish a predictive score of acute appendicitis more adapted  to our population and more practical.Methods :      A prospective study carried out in our  emergency department) over a period  of 2 years, involving patients presenting with acute abdominal pain in the right iliac fossa (FID). Datas interesting medical caracteristics , biologic and imaging were collected at baseline. diagnosis of acute appendicitis is confirmed by positive histological exam. Results :400 patients were enrolled and completed follow-up .the mean age of the study population was  33 +/-7 years. The sex ratio was 1.4 . Among these patients , for only 240 ( 60%) the diagnosis of appendicitis was comfirmed histologically  . The most common reason for consultation in this series is FID pain,this sign is present in 77.5% in the confirmed group group with p = 0.016. Univariate analysis identified other signs as  significantly predictifs ( p = 0.001 ) : radiation of pain from epigastrum to the umbilicus ,  positive rovsing sign and sensitive abdomen in palpation.In  multivariate analysis, our score was estabished, containing 7 variables : Vomiting>=2 épisode =1 point) , pain project From the epigastrium to the umbilicus =  2 point ,  positive  Rovsing sign =1 point , positive Blumberg sign = 1 point, sensitive abdomen =2 point , défense de la FID=  2 point and  White blood cells >10000 (hyperleucocytosis) =2 point .

The descrimination power is represented by the ROC curve. Area under the ROC curve of the appendicitis score was 0.874.This score can have a sensitivity of 99% and a specifity of 80%.

Conclusion :  many  scores have been developed (Alvarado, Andersson, François, ...), but are not common practice. A model based on variables easily available at ED, like our appendicitis score , can help ED physicians to diagnosis the acute appendicitis.


Houda BEN SALAH, Asma ZORGATI, Lotfi BOUKADIDA, Ali OUSJI (Sousse, Tunisia), Ikhlass BEN AICHA, Riadh BOUKEF
Kokkali
17:40

"Tuesday 26 September"

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AGM
17:40 - 18:40

EUSEM Annual General Assembly
for Members only

Mitropoulos
Wednesday 27 September
08:30

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A40
08:30 - 09:00

Keynote Lecture 3

Moderator: Christian HOHENSTEIN (PHYSICIAN) (BAD BERKA, Germany)
08:30 - 09:00 Constructive alignment: Curriculum, examination, training & beyond. Eric DRYVER (Consultant) (Speaker, Lund, Sweden)
Trianti Hall
09:10

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A41
09:10 - 10:40

Resilience

Moderators: Dr Barbara C HOGAN (Past President of the European Society for Emergency Medicine, EuSEM) (HAMBURG, Germany), Jan STROOBANTS (Head of the Emergency Department) (Brecht, Belgium)
Coordinator: Christoph DODT (Coordinator, München, Germany)
09:10 - 09:40 Resilience in emergency response systems. Raed ARAFAT (Speaker, Romania)
09:40 - 10:10 Burnout in Emergency Medicine. Pr Pinchas HALPERN (department chair) (Speaker, Tel Aviv, Israel, Israel)
10:10 - 10:40 Management instruments in the ED: tools for creating ED resilience. Dr Barbara C HOGAN (Past President of the European Society for Emergency Medicine, EuSEM) (Speaker, HAMBURG, Germany)
Trianti Hall

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B41
09:10 - 10:40

Falck Foundation - Paramedic-led research

Moderators: Demetrios PYRROS (Greece), Nagi SOUAIBY (Chief Editor) (Byblos, Lebanon)
Coordinator: Christoph DODT (Coordinator, München, Germany)
09:10 - 09:40 Creating a research supportive EMS organisation. Karen SMITH (Speaker, MELBOURNE, Australia)
09:40 - 10:10 Doing research as a paramedic. Veronica LINDSTRÖM (Researcher, Lecture) (Speaker, Stockholm, Sweden)
10:10 - 10:40 Best paramedic-led research papers 2011-2016. Marc SABBE (Medical staff member) (Speaker, Leuven, Belgium)
Mitropoulos

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C41
09:10 - 10:40

Mountain Medicine (Game Changers)

Moderators: Steffen HERDTLE (MD) (Jena, Germany), Peter PAAL (Head of Department) (Salzburg, Austria)
Coordinator: Christian HOHENSTEIN (Coordinator, BAD BERKA, Germany)
09:10 - 09:40 "high-level CPR": BLS with AED in Mountain Medicine. Peter PAAL (Head of Department) (Speaker, Salzburg, Austria)
09:40 - 10:10 "high-level science": the EURAC simulation center. Hermann BRUGGER (Head of Institute) (Speaker, Bolzano/Bozen, Italy)
10:10 - 10:40 "high-level HAP(P)ENESS": New strategies in management of HAPE. Philip SCOTT (Anaesthetic Registrar) (Speaker, Bristol, UK)
Banqueting Hall

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D41
09:10 - 10:40

YEMD - Research
Best abstracts

Moderators: Alice HUTIN (PH) (Paris, France), Jennifer TRUCHOT (MEDECIN) (Paris, France)
Coordinator: Basak YILMAZ (Coordinator, BURDUR, Turkey)
09:10 - 09:25 Tips to write a really good abstract and present it at EUSEM. Yonathan FREUND (PUPH) (Speaker, Paris, France)
09:25 - 09:40 From the abstract to the article. Colin GRAHAM (Director and Professor of Emergency Medicine) (Speaker, Hong Kong, Hong Kong)
09:40 - 09:55 3 best YEMD articles. Youri YORDANOV (Médecin) (Speaker, Paris, France)
09:55 - 10:10 #11057 - OP118 Predicting Utilization of Advanced Medical Imaging at Emergency Department Triage Using Patient-reported Reason for Visit and Immediately Available Medical Information.
OP118 Predicting Utilization of Advanced Medical Imaging at Emergency Department Triage Using Patient-reported Reason for Visit and Immediately Available Medical Information.

Background Emergency department (ED) crowding is associated with negative health outcomes, patient dissatisfaction, and longer length of stay (LOS) during the ED visit. Advanced imaging procedures are major contributors to increased ED LOS; earlier and improved prediction of patients’ need for advanced imaging may improve overall ED efficiency. We used information immediately available at ED triage including free text data regarding a patient’s reason for visit to predict utilization of advanced medical imaging (AMI): CT, Ultrasound (US), and MRI. Methods We used the 2012 and 2013 US National Hospital Ambulatory Medical Care Survey data to examine factors associated with the utilization of CT, US, MRI, and multiple AMI during a patient’s ED stay. We incorporated natural language processing (NLP) in multivariable logistic regression models to examine whether patient-reported reasons for visit available at time of ED triage improved prediction for AMI use.

Results: Among the 50,976 ED visits from 642 hospitals, 9,488 (18.6%) resulted in advanced medical imaging use including 7,240 CTs (14.2%), 1,585 ultrasounds (3.1%), 178 MRIs (0.35%) and 485 (0.95%) multiple types of AMI. Black patients had lower odds for all AMI use compared to whites (OR 0.64; 0.59-0.68). Odds of AMI use increased for patients with history of dementia (OR 4.0; 3.4-4.7), cerebrovascular disease (OR 3.1; 2.7-3.5), and diabetes (OR 1.7; 1.6-1.9). The predictive accuracy of the multivariable logistic models for all types of AMI use improved with the inclusion of patient-reported information using NLP: c-statistic increased from 0.74 to 0.82 for CT use, 0.76 to 0.83 for US use, 0.70 to 0.78 for MRI use, and 0.73 to 0.79 for multiple AMI use.

Conclusions: Patient-reported information available during ED triage can be used to predict the use eventual use of advanced medical imaging.  Models such as this which employ immediately available data and patient reported reasons for visit may help to identify patients earlier who will require various types of imaging during their ED stay.  These findings the potential to impact radiology and ED workflow. 


Justin SCHRAGER (Atlanta, USA), Rachel PATZER, Xingyu ZHANG, Joyce KIM
10:10 - 10:25 #11616 - OP119 An Analytical Approach to the Risk Stratification Screening of Sepsis utilizing The Systemic Inflammatory Response Criteria (SIRS) versus the Quick Sepsis Organ Failure Assessment (QSofa) in Portiuncula University Hospital, Ireland.
OP119 An Analytical Approach to the Risk Stratification Screening of Sepsis utilizing The Systemic Inflammatory Response Criteria (SIRS) versus the Quick Sepsis Organ Failure Assessment (QSofa) in Portiuncula University Hospital, Ireland.

In February 2016, the 3rd International Consensus for Sepsis Definitions were revised. A major change in the approach to sepsis was replacing the widely used SIRS criteria with the new qSofa Score. As the new Sepsis Guidelines replace existing medical practices, we can expect considerable impacts in terms of identification, management, and treatment of sepsis.
The objective of this paper was to analyze and compare the sensitivity and specificity between the SIRS criteria and the 2016 new qSofa Score in the detection and recognition of sepsis.
A retrospective study was carried out between the period of July 2015 to November 2015 where patients that were admitted due to sepsis (n=79). These patients were studied in terms of recognition in triage based on the SIRS criteria and the new qSofa Score which comprises of hypotension, altered mental status, and tachypnea. This study includes: the elements of recognition at triage, patient demographics (age and sex), common qsofa criteria, prevalence of type of sepsis that is captured most by the qSofa Score, a termed “Evolving qsofa” for patients whom at triage were qsofa negative but Developed qsofa Positive whist in the Emergency Department.
The total number of patients studied that were SIRS positive and admitted for sepsis were 79 (n=79). The mean age was 67, 35 males and 44 females. 28 had a respiratory source and 29 urinary tract infection. 43 sepsis cases were recognized using the qSofa (54.4% CI,43:79). Patients that developed a positive qsofa Score (whom were previously negative) were termed “Evolving qsofa” and were numbered at 10 (12.6% CI, 10:79). This brings the total to 53 positive qsofa in the time of study (67.08% CI, 53:79) (P>0.01). The mean time taken for a septic patient to be seen recorded at 39.17minutes. ICU admissions were 23 in total (29.11%, 23:79). All ICU admissions were patients with a positive qsofa (100% CI, 53:23). Positive Cultures numbered at 62 (78.4%, 62:79). The breakdown of positive qsofa criteria was as follows: Tachypnea numbered 34 (64.15% CI 34:53), Hypotension numbered 38 (71.69%, 38:53), Altered mental status numbered 26 (49.05%, 26:53). There were no mortalities resulting from sepsis in the ED during the term of the study.
Conclusively, this study stresses the consideration for the continuum of sepsis and proves that the qsofa has an extremely high specificity and overall accuracy in identifying septic debilitated patients whom will require ICU, and therefore superior to SIRS. However, the SIRS Criteria with its lowered Receiver operating Characteristics [ROC], possesses high sensitivity, enabling a wider cohort of patients presenting with infection to be triaged as likely sepsis and ensure robust Sepsis Screening.


Marcus JEE POH HOCK (Galway, Ireland), Kiren GOVENDER
10:25 - 10:40 #11751 - OP120 High-Dependency Observation Units: which parameters to identify patients at high risk of ICU transfer?
OP120 High-Dependency Observation Units: which parameters to identify patients at high risk of ICU transfer?

Aims: To evaluate independent predictors of ICU (Intensive care Unit) transfer in a multicentre population of patients admitted in two Emergency Department High Dependency Units (ED-HDU).

Methods: From June, 2014, to July, 2016, we recorded all patients admitted in the ED-HDU of University Hospital Careggi and in the ED-HDU in the Azienda Ospedaliero - Universitaria Policlinico - Vittorio Emanuele in a standardized database;; after 25 months, we analyzed the database in order to identify predictive parameters of an adverse outcome. To standardize comorbidity, Charlson index was calculated; SOFA score calculation was employed to evaluate organ dysfunction. The primary end-point was ICU admission.

Results: During the period June 2014-July 2016, 3311 patients were admitted in the two Units, 1822 in Florence and 1489 in Catania, mean age 72±16 years; overall HDU mortality rate was 5% (n=171). The most frequent admission diagnosis were COPD exacerbations (9%), ischemic (11%) and congestive (19%) heart disease, trauma (7%) and cardiac arrhythmias (18%). Overall 18% of patients presented a respiratory failure requiring non-invasive ventilation and 7% had a shock requiring vasoactive medications.

At HDU admission, 32% of patients presented an infections; respectively 4 and 8% of patients showed a respiratory (pH <7.3 with pCO2 >45 mmHg) or metabolic acidosis (Base excess ≥ -5 or lactate level 1.5 time the reference level); mean SOFA score, calculated on the basis of the worst values in the first 24 hours, was 3.8±3.3. Overall 208 (7% of HDU survivors) patients were transferred to an Intensive Care Unit (ICU): compared with patients with a good prognosis, age was comparable between patients transferred to ICU and the others (71±15 vs 72±16, p=NS), while comorbidity burden (Charlson index 3.1±2.5 vs 2.8±2.6, p=0.046) was only slightly higher in patients admitted to ICU . Presence and number of organ insufficiency actually differentiated patients’ disposition: compared with patients transferred to an ordinary ward, number of organ failure was significantly higher in patients transferred to ICU (1.0±0.9 vs 0.6±0.7, p<0.001) as well as the presence of respiratory (41 vs 15%), renal (39 vs 32%) and cardiovascular (18 vs 7%) failure.  A sepsis (23 vs 10%), as well as a septic shock (11 vs 4%), was more frequent among patients transferred to an ICU.

In a multivariable analysis which included all variables significantly different according to ICU transfer (SOFA score, Charlson index, presence of acidosis and presence of infection at admission) SOFA score was independently associated with a untoward prognosis in the whole study population (RR 1.23; 95%CI 1.16-1.29, p<0.001); the result was confirmed among patients admitted in Catania Center (RR 1.39; 95%CI 1.26-1.52, p<0.001) and Florence center (RR 1.23; 95%CI 1.15-1.32, p<0.001).

Conclusions: a higher SOFA score was the only independent predictor of ICU admission in an unselected population of HDU patients. 


Federico MEO, Arianna GANDINI (Florence, Italy), Paola NOTO, Giuseppe MANGANO, Giuseppe CARPINTERI, Francesca INNOCENTI, Riccardo PINI
Skalkotas

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F41
09:10 - 10:40

Free Papers Session 12

Moderators: Dr George NOTAS (DOCTOR) (HERAKLION, Greece), Anastasia ZIGOURA (Greece)
09:10 - 09:20 #11104 - OP100 How often does a routine urinalysis help with emergency department clinical decision making ?
OP100 How often does a routine urinalysis help with emergency department clinical decision making ?

Objective: to determine how often the urinalysis (UA) contributes to clinical decision making and/or disposition decisions in the emergency department (ED).

 

Methods:

During 12 consecutive days, the records of all adult patients presenting to our ED were reviewed to see whether or not they a UA was ordered during their ED visit. In addition to this variable, patient demographics, and whether it influenced clinical decision-making (based on the medical decision-making section of the physician chart) or disposition decision were abstracted.

 

Results:

A total of 559 patients presented during the study period, of which 66% were female. The median age was 51, with an interquartile range of 35 to 68 years. 294 (38%) presented on a weekend, defined as Friday 7pm to Monday 7 am.101 (35%) presented during the night shift, defined as arriving between the hours of 7pm-7am.

265 (65%) were first seen by a physician assistant (PA) and then seen by an MD. 138 (25%) were seen by a PA alone.  A total of 232 patients (42%) were admitted. 287 patients (51%) had a UA ordered in the ED.

193 (35%) had a UA ordered by the PA. 94 (17%) had a UA ordered by the physician. The UA was cancelled in 50 patients.

 

Patient disposition decision was made prior to UA resulting in 60 cases (25%).

Of these, 36 (60%) were women, and the median age was 65, with an interquartile range of 49 to 73 years.

29 (48%) were seen on the weekend. 20 (33%) were seen on the night shift. 56 (93%) not seen by PA.18 (30%) ordered by PA. 42 (70%) ordered by MD. 100% UA cancelled

 

The UA was used in clinical decision making in 118 (66%). Univariable correlates included:

Being female (P=0.0050, 95% CI 0.0068 - 0.378)

Being older (P<0.0001, 95% CI -0.010 to -0.004)

Being first seen by a PA then a physician (P=0.0486, 95% CI= 0.0048 - 0.1555)

More often in discharged patients (P<0.0001 95% CI -0.6749 to -0.4487)

 

Conclusion: Our results suggest that a routine UA may not impact clinical decision making up to 33% of the time, nor alter or disposition decision one out of four times. Unnecessary tests place additional burden on the patient, and the ED personnel, and perhaps should be reconsidered.

 

 


Bethany BALLINGER (Orlando), Latha GANTI, Ambika ANAND
09:20 - 09:30 #10850 - OP101 Impaired cognition is highly prevalent and independently associated with adverse outcomes in older patients presenting to the emergency department; the APOP study.
OP101 Impaired cognition is highly prevalent and independently associated with adverse outcomes in older patients presenting to the emergency department; the APOP study.

Introduction

We investigated whether impaired cognition is associated with adverse outcomes in older emergency department (ED) patients, because this association could have large implications for ED management and follow-up after disposition. 

Methods 

A prospective multi-center cohort study was performed in all acutely presenting older patients visiting the ED (APOP study). Demographic data, disease severity and geriatric characteristics were collected during the first hour of the ED visit. Cognition was measured using the 6 Item Cognitive Impairment Test (6CIT). Cognitive impairment was defined as a 6CIT ≥11, self-reported dementia or the inability to perform the cognition test. Adverse outcome after three and twelve months was defined as a 1 point decrease in Katz-ADL, new institutionalization or mortality. Multivariable regression analysis was used to assess whether impaired cognition independently associates with adverse outcome. 

Results 

Of the 2131 included patients 588 (27.6%) had cognitive impairment. A total of 375 (24.5%) patients with normal cognition suffered from adverse outcomes after three months, compared to 280 (47.8%) patients with impaired cognition. The association remained after correction for baseline functional status, disease severity and comorbidities (OR 1.71, 95%CI 1.36-2.15). After twelve months 332 (27.9%) patients with normal cognition suffered from adverse outcome, compared to 240 (54.5%) patients with impaired cognition (adjusted OR 1.89, 95%CI 1.46-2.46). 

Key conclusions 

Cognitive impairment is highly prevalent in older ED patients and is associated with adverse outcome after three and twelve months, independent of baseline functional status, disease severity and comorbidities. This emphasizes the importance for ED physicians to assess cognition and possibly intervene.


Jacinta LUCKE (Haarlem, The Netherlands), Jelle DE GELDER, Christian HERINGHAUS, Jaap FOGTELOO, Sander ANTEN, Gerard-Jan BLAUW, Bas DE GROOT, Simon MOOIJAART
09:30 - 09:40 #10952 - OP102 Determinants of Self-Rated Health in older adults before and three months after an emergency department visit; a prospective study.
OP102 Determinants of Self-Rated Health in older adults before and three months after an emergency department visit; a prospective study.

Introduction

Older patients often experience adverse health outcomes after an Emergency Department (ED) visit, which potentially affects quality of life (QOL). Self-rated health (SRH) is a way of exploring QOL and is an important outcome of interest in older adults. There are only a few reports on SRH and its determinants in older patients visiting the ED. The aim of this study was to identify the determinants of decline in SRH in older patients three months after visiting the ED. 

 

Methods 

This study is an analysis of the data from the Acutely Presenting Older Patient (APOP) study in which all patients aged ≥ 70 years, attending the EDs of the Leiden University Medical Center (LUMC) and Alrijne Hospital in the Netherlands were included. At presentation and after three months, patients were asked to score their general health during the last month excluding the reason of their visit to the ED, with zero being the worst and ten being the best imaginable situation. The main outcome was a decline in SRH defined as a transition of a SRH ≥6 at baseline to a SRH

 

Results 

At baseline there were 1219 (81.2%) patients with a sufficient SRH (SRH ≥6) and 283 (18.8%) patients had an insufficient SRH (SRH <6). Three months after the ED visit 870 patients had a stable SRH (71.4%), 209 patients declined in their SRH (11.5%) and 142 patients died or there was no follow-up SRH available (17.1%). Independent factors associated with a decline in SRH were: male gender (OR 1.84, 95 % CI 1.19-2.85), living alone (OR 1.58, 95 % CI 1.01-2.47), living in residential care or nursing home (OR 2.76, 95 % CI 1.21-6.27), number of different medications (OR 1.08, 95 % CI 1.03-1.13), using a walking device (OR 1.73, 95 % CI 1.05-2.82) and the Katz-ADL score (OR 1.23, 95 % CI 1.02-1.48). Patients who experienced functional decline three months after an ED visit, show a steeper decline in mean SRH (0.68 points) compared to patients who did not experienced functional decline (0.12 points, p<0.001).  

 

Key conclusions 

Decline in SRH after an ED visit in older patients is mainly dependent on factors of functional capacity and functional decline. Preventive interventions to maintain functional status could be the solution to maintain SRH. 


Floor VAN DEUDEKOM, Jelle DE GELDER, Jacinta LUCKE, Anneleen OOSTENDORP - LANGE, Sander ANTEN, Blauw GERARD JAN, Bas DE GROOT, Simon MOOIJAART (LEIDEN, The Netherlands)
09:40 - 09:50 #10982 - OP103 Emergency admissions in older patients: a population-based survey.
OP103 Emergency admissions in older patients: a population-based survey.

Background: Older patients comprise a major proportion of all emergency admissions and associated costs. As this population grows, there will be a mounting demand for health care services and emergency services in particular. In this study, we investigated the burden and costs related to older patients’ emergency department (ED) use.

Methods: Consecutive patients aged 80 years or over admitted to a high-volume, collaborative ED during a two-year study period (January 2015 to December 2016) were included. The hospital provided primary and tertiary care emergency services to a population of 226,696 inhabitants (10,991 aged 80 years or over). Patient demographics, diagnoses, costs of ED care were retrieved from hospital records. Only in-hospital costs of ED care and examinations were included. The key factors under analysis were the incidence of emergencies and the associated costs of ED care.

Results: A total of 12,177 patients (median age 85 years, range 80-114 years; 65% female) had 24,441 ED admissions (14% of all ED admissions) during the two-year study period. The incidence of emergencies increased from 387/1,000/year (133/1,000 inhabitants of this age group required emergency services) in patients aged 80-89 year to 511/1,000/year (147/1,000) in those aged 90 years or over (p<0.001). High-frequency users (≥5 admissions/year, n=621, range 5-46 admissions) covered 6% of all ED admissions in patients aged ≥80 years.

Older patients were most often diagnosed to suffer from different types of non-specific symptoms (24%), cardiovascular diseases (18%), injuries (17%), respiratory diseases (8%), genitourinary diseases (8%) and gastrointestinal diseases (5%). Typical specific diagnosis included pneumonia (5%), femoral fracture (3.1%), cerebral infarction (2.3%), acute pyelonephritis (2.1%) and acute myocardial infarction (1.4%).

Twenty-two per cent of patients required tertiary care in our hospital, 38% were discharged home and the rest (40%) to other hospitals, to primary care centres or to nursing homes. Only 0.2% was admitted to intensive care unit. There was a steady increase in the costs according to age; population-size adjusted costs of ED care in inhabitants aged 90 years or more were over 1.3-fold (430 euros/same aged inhabitant) compared to that of those aged less than 90 years (324 euros). The mean costs of a single admission in high-frequency users did not differ significantly from those of requiring emergency evaluation only once. Patients requiring multiple admissions covered 88% of all costs of ED care in older patients.

Conclusions: A large share of older people needs ED services annually and many have repeated visits. Despite high use of ED resources and consequent costs, no specific diagnosis could be made in one-fourth of cases. Potentially avoidable ED admissions and repeat admissions could be a target for cost-reductive initiatives.


Mika UKKONEN (Tampere, Finland), Esa JÄMSEN, Rainer ZEITLIN, Tuuli LÖFGREN, Satu-Liisa PAUNIAHO
09:50 - 10:00 #11823 - OP104 End-of-Life decisions rate in the prehospital field for fragile patients.
OP104 End-of-Life decisions rate in the prehospital field for fragile patients.

Background

The management of the elderly or patients with severe conditions has increased in emergency field. In the prehospital setting, teams are often confronted with the absence of data allowing to rule on therapeutic limitations. Emergency physicians must therefore discuss and apply therapeutic limitations, i.e. End-of-Life (EoL) decisions. These decisions should be recorded in the medical transport sheet (MTS). The aim of our study is to assess the EoL decisions rate on the Emergency Medical Service (EMS) MTS of patients considered as fragile.

Methods
We performed a monocentric, 1.5-month retrospective analysis of the medical records of patients managed in a mobile intensive care unit of an EMS located in an urban zone.
The inclusion criteria were: patient age > 85 years with a lost of autonomy and patients with an incurable disease.
The primary interest criterion was the reported EoL decisions rate, i.e. decided by the EMS and indicated on the MTS.
Secondary criteria were patients’ characteristics: the pathology concerned, the EoL decisions rate taken before the team’s arrival, the destination service when transported, and the rate of contact with the family to participate in decision-making recorded in the MTS.

Results
From mid-October to late November 2016, 63 patients met the inclusion criteria. Thirty-five (56%) were men; median age was 88 [IQR: 81-91] years. The management took place at home, at a nursing home or at a rehabilitation care service in respectively 45 (71%), 12 (19%) and 6 (10%). Pathology concerned were cardiac arrest, neurology, respiratory, cardiology, metabolic and others in respectively 18 (29%), 16 (25%), 15 (24%), 5 (8%), 3 (5%) and 4 (6%) cases.

EoL decisions were known before EMS intervention in three cases. For the others, EoL decisions were written on the MTS for 15 patients. The reported EoL decisions rate was 24% (95% CI: 14% - 36%). After medical evaluation, three (5%) were left alive at home, 20 (32%) died on scene and 40 (63%) were sent to hospital. On those, 38 (60%) patients were sent to an emergency room and two (3%) were sent to an intensive care unit with a massive haemorrhagic stroke. Family was contacted in 17 (27%) cases to participate in decision-making.

Conclusion

Reported EoL decisions rate for elderly patients without autonomy or patients deemed incurable was low. Furthermore, transports’ rate to emergency department was high and the number of patients left alive on scene was low. This could be considered as a gap in the ethical care of very fragile patients. A service procedure will be implemented to improve practices.


Margot CASSUTO (Garches), Paul-Georges REUTER, Cécile URSAT, Pauline DESWARTE, Caroline PÉTISNÉ, Anna OZGULER, Michel BAER, Thomas LOEB
10:00 - 10:10 #11925 - OP105 Loss of autonomy and home carers in elderly patients visiting the Emergency Department.
OP105 Loss of autonomy and home carers in elderly patients visiting the Emergency Department.

In emergency departments (ED), elderly patients are an increasing part of visiting patients. Their admission rate is higher than young patients and their lenght of stay is longer partially because admission can lead to loss of autonomy. Assessing autonomy level and home carers presence is not always done through ED visit. However it could help anticipate their care pathway after ED visit. We want to assess what do elderly patients visiting ED become depending on their autonomy level and the presence of carers at home before the event. We also want to draw the epidemiological portray of elderly patients and assess their mortality rate.  

Method : Prospective multicenter cohort study with inclusions done on a given day in 147 Emergency Departments. Patients ≥ 80 years old have been included and questionnaire filled in by the doctor in charge. It was dealing with patient characteristics, emergency situation, medical care, autonomy, home carers, and situation on day 30. Our main aim was to assess their mortality rate. Secondary objectives were to analyse patients characteristics and especially in terms of autonomy and home assistance. We also wanted to evaluate what do these patients become through hospitalization and institutionalization rate at day 30. We completed statistical analysis through descriptive statistics and a second part of this work will be to perform logistic regressions in order to assess association between mortality, hospitalization, institutionalization and existence of home assistance. This last part has not been done yet. Regression will adjust for age, sexe, comorbidities, severity, loss of autonomy, socioeconomic category.

Results : n= 1659 patients were included. Mean age was 86,9 ±4,7 years old. 60,7% were women. 72% were living at home (among which 79,5% with general home carers and 44,8% with professional carers). Only 2,2% had no medical history, 62,9% had more than 3 daily treatments and 36,6 % had cognitive impairment. Among patients living at home, 60,1% had mild impairment in Activity of Daily Living and 2,5% had extreme loss of autonomy. 13,7% of visiting patients had severe conditions and 3,7% were admitted in intensive care. 64,7% have been admitted after ED visit. On day 30, mortality rate was 8,3% and 30,3% of admitted patients were still hospitalized or had been institutionalized. Among patients living at home : 29,8% of patients with home carers were still admitted or had been institutionalized on day 30 vs 24,2% of patients without home carers, p<0,05. 

 Conclusion : Elderly patients are mainly living at home, most of them have at least mild loss of autonomy and 44,8% have professional carers to help them deal with their dependance. Admission and mortality rate are high. On day 30, a third of elderly patients are still hospitalized. Logistic regressions are needed to go further and to analyze association between the existence of home carers in dependent patients and hospitalization rate after visiting ED.


Anne-Laure FERAL-PIERSSENS (Bobigny), Fatima SEHIMI, Gustave TOURY, Clement CARBONNIER, Marie BALLESTER, Philippe JUVIN
10:10 - 10:20 #11263 - OP106 Improving ED working conditions, employee well-being, and patient satisfaction: An intervention study.
OP106 Improving ED working conditions, employee well-being, and patient satisfaction: An intervention study.

Background

ED work systems encompass a multitude of work stressors that impact ED professionals’ well-being and delivery of patient care. Little is known about effective interventions to improve the psychosocial ED work environment with positive effects on professionals’ mental health and quality of care. The aim of this intervention study was to analyze the prospective effects of an employee-centered intervention (“health circles”) with regard to psychosocial work stressors, mental well-being, and patient satisfaction.

Methods

This study established a two-wave interrupted time series design with a time lag of one year. The study setting comprised a multidisciplinary German ED with an annual volume of approx. 84000 patients. All ED employees (nurses, physicians, and administrative staff) were invited to participate in a survey. Validated and standardized instruments were used to measure psychosocial work stressors and mental well-being. Additionally, patients were surveyed on-site with a short questionnaire about their satisfaction with quality of care on 40 randomized days at both waves. Between baseline and follow-up, ten interdisciplinary moderated “health circles” with ED nurses and physicians were conducted on different topics of ED work organization and ED leadership. Differences over time and associations between study variables were calculated with SPSS 23.0. 

Results

Overall, N = 149 surveys were completed. 40 ED employees responded at both waves. A total of 1418 patients was surveyed. Employees reported high levels of interruptions, time pressure, and low participation opportunities throughout both waves. However, improvements after one year were reported in autonomy (p=.014), while employees’ perceptions of staffing levels (p=.046) and social support (p=.002) deteriorated. Concerning mental well-being, general job satisfaction declined (p=.013) and depersonalization increased (p=.027). Psychosocial work stressors and ED professionals’ mental well-being were strongly associated at both waves. There was evidence on divergent trends in the evaluation of psychosocial work stressors and mental well-being between nurses, physicians, and administrative staff. However, patient satisfaction with organization of care, with interactions and information from care providers, and with waiting times significantly improved from baseline to follow-up (all scales p<.001).

Discussion and Implications

To our knowledge, this is the first systematic study of a participative intervention in an ED which evaluates longitudinal effects on psychosocial work stressors, mental well-being, and patient satisfaction. We observed significant changes in autonomy, staffing, and social support of ED employees, their job satisfaction and depersonalization, and finally, significant improvements in patient satisfaction with quality of care. Our results suggest that employee-centered interventions that target the psychosocial work environment in EDs might improve quality of care.


Anna SCHNEIDER (Munich, Germany), Markus WEHLER, Matthias WEIGL
10:20 - 10:30 #11364 - OP107 Capillary lactate vs POCT venous lactate in the emergency department.
OP107 Capillary lactate vs POCT venous lactate in the emergency department.

Background

An elevated blood lactate level (hyperlactatemia) is a sensitive marker that may be used to identify critically ill patients. Capillary lactate measurement using handheld devices may allow for rapid determination of test results and these devices can be used in the pre-hospital setting. The present study aimed to investigate the agreement of capillary lactate measured using handheld lactate analyzer compared to the reference- venous blood lactate level assessed using a point of care test (POCT) blood gas analyzer in the Emergency Department (ED).

 

Methods

Prospective observational study of patients presenting to the ED in Hong Kong. Patients triaged as ‘urgent’ (Category 3 of the 5 category triage scale), aged 18 years or above, who presented to the ED during 2016 were recruited. Venous and capillary blood samples were collected for lactate analysis. Venous lactate levels measured by blood gas analyzer were used as a reference (VL-Ref). Capillary lactate levels were measured using two handheld analyzers (Nova StatStrip Xpress Lactate Meter and Lactate Scout+ Analyzer) (CL-Nova and CL-Scout+). Venous lactate measurements were also performed using two handheld analyzers (VL-Nova and VL-Scout+). Agreement of lactate levels from handheld analyzers with the reference blood gas analyzer was determined using Bland-Altman agreement analysis.

 

Results

Two hundred and forty patients (mean age 69.9 years; 54.2% males) were recruited between March and July 2016. The result of VL-Ref ranged from 0.70 to 5.38 mmol/L, with a mean of 1.96 mmol/L. 63.75% and 36.25% showed lactate level (VL-Ref)

 

Discussion

An overall low systemic bias were observed in CL-Scout+ (bias: -6.2%) and VL-Scout+ (bias: 13.0%), suggesting the potential clinical utility of Scout+ handheld analyzer for screening patients who should or should not have further formal lactate measurement  using a POCT blood gas analyzer or analysis in the central laboratory. In addition, POCT lactate may not be available in all EDs, or in the pre-hospital setting. Screening lactate levels using a handheld analyzer could provide information to hasten the identification of patients at risk, to make early decisions for further treatment.


Ronson Sze Long LO, Dr Kevin Kei Ching HUNG (Hong Kong, Hong Kong), Ling Yan LEUNG, Kwok Hung LEE, Chun Yu YEUNG, Suet Yi CHAN, Colin GRAHAM
10:30 - 10:40 #11770 - OP108 Agreement of emergency department and hospital diagnosis of septic shock.
OP108 Agreement of emergency department and hospital diagnosis of septic shock.

Title: Agreement of emergency department and hospital diagnosis of septic shock.

Background: Sepsis is the leading cause of shock in the emergency department (ED). Clinical suspicion of infection is crucial to early identification of septic shock. No studies of agreement between real-time emergency physician (EP) impression and hospital diagnosis of septic shock have been identified in the literature.

Objectives: The primary objective was to evaluate agreement between real-time EP impression and hospital diagnosis of septic and non-septic shock.

Methods: This was an observational cohort study on patients presenting with shock in an academic tertiary ED from January 2015 to January 2017. Subjects were identified through an interactive shock alert tool that alerts EPs instantaneously when a patient has either a systolic blood pressure < 90mmHg or lactate ≥ 4mmol/L. The alert requires the EP to click their impression. Two-by-two tables for ED impression at the time of alert against hospital diagnosis were computed. Agreement of real-time EP impression was evaluated by calculating sensitivity, specificity, predictive values and likelihood ratios with 95% confidence intervals (CIs).

Results: A total of 2208 ED visits met inclusion criteria. After applying exclusion criteria, 1520 remained and were included in the study. The mean age was 61.1 (SD 18.2) years, and 56.7% were men. There was a good hospital agreement with the EP impression of septic shock, with the following performance: sensitivity 77.3% (95% CI 73.7-80.5), specificity 89.2% (95% CI 87.0-91.0), positive predictive value (PPV) 81.7% (95% CI 78.3-84.7), negative predictive value (NPV) 86.2% (95%CI 83.9-88.3), positive likelihood ratio 7.153 (95% CI 5.919-8.644) and negative likelihood ratio 0.255 (95% CI 0.219-0.296). Dehydration was most common EP impression of non-septic shock, among those who turned out to have hospital diagnosis of septic shock.

Conclusion: Good agreement between real-time EP impression of septic and non-septic shock and hospital diagnoses was shown by PPV of 81.7% (95% CI 78.3-84.7), and NPV of 86.2% (95%CI 83.9-88.3). This outperforms available lab testing in diagnosing sepsis.


Miriam V. THYGESEN (Aarhus, Denmark), Casey M. CLEMENTS, Vitaly HERASEVICH, Hans KIRKEGAARD, Bo E. MADSEN
Kokkali

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E41
09:10 - 10:40

EM development: The International ways

Moderators: Panos AGOURIDAKIS (IRAKLION, Greece), Bernard FOEX (Consultant in Emergency Medicine and Critical Care) (Manchester, United Kingdom)
09:10 - 09:40 The Development Tendency of Emergency Medicine in China. Wang ZHONG (Speaker, China)
09:40 - 10:10 Cultural contamination for a better European EM. The exchange program for young doctors. Roberta PETRINO (Head of department) (Speaker, Italie, Italy), Pr Riccardo PINI (Director, E.D. High Dependency Unit) (Speaker, Florence, Italy)
10:10 - 10:40 Development of EUSEM Research Network. Said LARIBI (PU-PH, chef de pôle) (Speaker, Tours, France)
MC-3
10:45

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PH6 - S4
10:45 - 11:05

E-Poster Highlight Session 6 - Screen 4

10:45 - 10:50 #11334 - Reducing unnecessary and high cost laboratory testing in Emergency Department: a multilevel intervention.
Reducing unnecessary and high cost laboratory testing in Emergency Department: a multilevel intervention.

Introduction

Laboratory blood tests are an integral part of the diagnostic investigation performed in patients presenting to emergency department (ED), but they are also widely recognized as a key form of potential waste in health care utilization. The aim of this study is to determine if a multilevel intervention based on optimization of test profiles and awareness of medical staff about costs and appropriate use of high cost tests (troponin Ic, D-dimer, procalcitonin and brain natriuretic peptide) could reduce the number of requested tests and costs without affecting ED performances.

Methods

A before-and-after study in an adult tertiary-referral teaching hospital ED was conducted. Laboratory test profiles used in pre-intervention period until 30th June 2016 (chest pain, sepsis, surgical, trauma, thromboembolism profiles) were modified, reducing profile to basic and major trauma and cutting by 50% the number of tests in each profile. All ED physicians were informed with one hour meeting about the expense of laboratory tests requested from ED and also about the appropriate use of the most frequent high cost tests in June 2016 and after six months in December 2016. The 8 months intervention period (from 1st July 2016 to 28th February 2017) was compared with the same 8 months in pre-intervention period (from 1st July 2015 to 28th February 2016).

Main outcomes were the total number of laboratory blood tests and the number of high cost tests ordered. The secondary outcomes were the cost of laboratory blood tests and ED performances. The costs in Euro were derived from the Tuscany region pathology public price schedule, the ED performance indicators considered in the study were waiting time from arrival to discharge or admission, number of death in ED and re-entry within 72 hours from discharge.

Results

There was no significant difference in patients presentation among intervention (61,976 pts) and pre-intervention period (61,154 pts). Total laboratory tests requests from ED decreased by 209,041 tests with a 347.4 tests/100 patients reduction (-37.1%) in intervention period compared to pre-intervention period (p<0.05). Total costs decreased of 608,079€ in 8 months with 1,026€/100 patients reduction (-30.6%) in the intervention period compared with pre-intervention period. High cost test requests decreased by 11,457 (-27.3%, p<0.05), participating in costs reduction for 197,206€ (367€/100 patients, -30.5%). No significant differences were found in the performance of ED indicators.

Conclusions

Multilevel intervention by modification of routine laboratory test profiles and educational meetings for ED medical staff is an effective method to reduce laboratory test ordering and costs in the ED without affecting ED performances.


Linda FALLAI, Simone VANNI (Florence, Italy), Laura BETTI, Cesare DURANTI, Alessandra FANELLI, Agostino OGNIBENE, Stefano RAPI, Stefano GRIFONI, Peiman NAZERIAN
10:50 - 10:55 #11107 - Implementation of real-time Kaizen in the emergency department.
Implementation of real-time Kaizen in the emergency department.

Background: Kaizen, or continuous improvement, is a core principle in lean production. Healthcare organizations have sought ways to use this methodology in clinical practice to improve hospital quality and patient safety. Traditional deployment of lean process improvement plans (PIPs) relies on retrospective evaluations gathered from reiterative project lifecycles that often take months to years to complete. However, the Emergency Department (ED) operates under a fast-paced and unpredictable clinical environment. Thus, a real-time Kaizen model is needed to adjust to the ever-changing dynamics of the ED.

Methods: During a five week period, the ED at Aarhus University Hospital, Denmark was transformed into a live testing environment. Five test sessions were conducted to test PIPs aimed to optimize staff’s functional roles, patient intake flows, and ED space utilization. At the start of each session, the ED leadership team-including the department chair and head nurse, held an all staff meeting to introduce the PIP. Next, a five hour test phase was conducted to assess the PIP in live clinical production. For example, one PIP looked to streamline the patient intake process, where the secretary would accompany the nurse during patient rooming to minimize duplication of data collection. Another PIP introduced new responsibilities to the ED physician during trauma resuscitations. Each PIP was trialed for five hour as the leadership team performed real-time “gemba walks” around the ED to observe the change impacts. At the conclusion of the test session, all operation and clinical flow returned to normal, and a one hour debrief was held to gather feedback from participants and observers. Lessons learned from the first session would then be built upon during the next test. Each subsequent trial would increase in scale and complexity, involving more staff, patient care areas, and other specialty departments. Should an overall positive effect be determined at the conclusion of the 5 week test period, the PIP would then be officially implemented into daily practice.

Results: Change impacts captured from each PIP were organized onto a 2x2 matrix (expected vs unexpected findings, advantages vs. disadvantages). This enabled the ED leadership team to identify unexpected advantages that would have otherwise been missed without real-time testing in a live clinical environment. Furthermore, serial PIP trials allowed for targeted revisions with each subsequent session, thus greatly expediting the process improvement life cycle. Finally, the ED leadership team was on-site to witness the change impacts. This facilitated effective change management as it allowed key stakeholders to own and champion the PIPs from strategic planning to clinical implementation.

Conclusion: This adaptive Kaizen methodology allows for real-time assessment and implementation of process improvements in the dynamic clinical environment of the ED. 


Rona WANG (Rochester, USA), Ole MØLGAARD, Pia STIE-SVENDSEN, Jette Møller AHRENSBERG, Bo E. MADSEN, Hans KIRKEGAARD
10:55 - 11:00 #11102 - Structural reform of acute care in Denmark: Designing the prototype emergency department.
Structural reform of acute care in Denmark: Designing the prototype emergency department.

Background: To date, emergency medicine is not a formalized medical specialty in Denmark. Emergency medical care formerly fell under the provision of three separate entities: pre-hospital system staffed with board certified anesthesiologists, on-call primary care system provided by the general practitioners (GPs), and hospital inpatient departments comprised of various specialists. In 2007, the Danish National Board of Health recognized the need for a new emergency care model, which led to the mandate for 24 hour acute care coverage from 6 core specialties (internal medicine, orthopedic surgery, general surgery, anesthesiology, diagnostic radiology, and biochemistry), and for the designation of a single hospital-based unit for receiving acute patients, the emergency department (ED).  

Challenge: Aarhus University Hospital, a leading academic center in Denmark, is set to expand to become one of the largest and most comprehensive hospitals in Europe. The new medical campus is anticipated to be fully operational by 2020, and a new ED was included in the design to comply with the 2007 emergency care mandate. However, as acute patients were traditionally triaged directly to specialty departments, no prior ED model existed to facilitate the initial assessment and hospital management of acute patients. Thus, preparation in the transitional period was needed to redefine and reorganize the delivery of emergency medicine under a single hospital unit-the ED.

Prototype Design: A central call line was established in the new ED to receive all acute patient referrals from the GPs. This allowed the ED to become the single coordinator of acute patients in need of hospital management. However, because no specialty had the overarching core competency to manage all acute patients, triage of these patients were divided based on the training and medical background of the physicians. Dedicated full-time specialists were recruited onto the ED staff, such that board certified orthopedic surgeons managed acute injuries and board certified internists managed acute medical complaints. This reduced dependence on other departments to provide staffing resources and clinical expertise in the ED. Next, the organization of acute patients requiring overnight stays was designed to match the medical competencies of the nursing staff. For example, abdominal pain patients likely requiring surgical consults were grouped and staffed by nurses with prior experience caring for surgical patients. This ensured an appropriate level of quality and patient safety in a new ED actively undergoing the development of its staff. Finally, the new ED leadership team made special efforts to emphasis the guiding principles and mission of the new department. This allowed for effective change management.

Results and Conclusion:  The prototype ED allowed for the integration and centralization of emergency care under a new structural model that shifted away from traditional acute care practice.


Rona WANG (Rochester, USA), Jette Møller AHRENSBERG, Ole MØLGAARD, Bo E. MADSEN, Hans KIRKEGAARD
11:00 - 11:05 #11488 - A portable prototype magnetometer to identify chest pain patients who do not have ischaemic heart disease.
A portable prototype magnetometer to identify chest pain patients who do not have ischaemic heart disease.

Background: Distinguishing between acute coronary syndrome (ACS) and non-ischaemic heart disease (NIHD) or non-cardiac chest pain is a major challenge in emergency medicine. Patients presenting to the Emergency Department with chest pain are routinely triaged through a series of tests, such as an ECG, alongside lengthy diagnostic blood tests. However, in approximately 75% of patients, their chest pain is of a non-cardiac origin. The ability to detect ACS and rule-out NIHD earlier in some of these patients would have a positive impact on outcomes and save hospital resources. Magnetocardiography (MCG) is a non-invasive, highly-sensitive technique that has been extensively used to measure and map cardiac magnetic fields. A portable prototype magnetometer was recently developed for use in acute and routine clinical settings. We assessed the predictive capability of the magnetometer to differentiate non-cardiac subjects and patients whose chest pain had a non-ischaemic origin from those with ischaemic heart disease (IHD).

Methods: MCG data were collected from two studies. A clinical performance study was conducted in patients ≥25 yrs with suspected IHD and in healthy age-matched volunteers. A pilot clinical study was performed in patients ≥18 yrs with NSTEMI requiring hospitalisation for chest pain (≥50ng/L troponin 12h post-onset of chest pain) and in a control group with NIHD and chest pain. Study participants were grouped to provide greater statistical power to differentiate patients from controls: IHD patients (n=70), age-matched controls (n=69) and young (<30 yrs) healthy volunteers (n=37). MCG scans were recorded in an unshielded room. Between-group differences were explored by analysis of variance. The predictive capability of the magnetometer was assessed using logistic regression based on 10 potential predictive factors (termed ‘predictors’).

Results: Overall, 55/63 patients and 51/60 healthy volunteers were eligible for analysis in the clinical performance study. In the pilot clinical study, 15/21 patients with NSTEMI and 18/21 patients with NIHD were eligible. Of 10 potential MCG predictors, three showed a significant difference between the patient group and the age-matched controls (p<0.001) and eight showed a significant difference between the patient group and the young healthy volunteers (p<0.001). Logistic regression comparing patients with controls yielded a specificity of 36.4%, sensitivity of 94.0% and a negative predictive value for the rule-out of IHD of 97.2% (area under the curve 0.77).

Discussion: The portable prototype magnetometer effectively ruled-out approximately 35% of healthy subjects and patients whose chest pain had a non-ischaemic origin from those with IHD. The predictive capability of the device fills an unmet need for a test that can rapidly identify non-cardiac patients, thereby reducing the number of patients presenting with chest pain who currently have to go through unnecessary and costly screening procedures. 


Mark KEARNEY, Shima GHASEMI-ROUDSARI, Abbas AL-SHIMARY, Rowena BYROM, Lorraine KEARNEY, Benjamin VARCOE (Leeds, United Kingdom)
E-Poster Area

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PH6 - S1
10:45 - 11:05

E-Poster Highlight Session 6 - Screen 1

Moderators: Anthony GERASKLIS (Greece), Felix LORANG (Consultant) (Erfurt, Germany)
10:55 - 11:00 #11252 - Utility of troponin after syncope.
Utility of troponin after syncope.

Introduction: There is currently conflicting evidence of the role of troponin testing in patients presenting to the emergency department (ED) after syncope. This study aims to assess the yield and utility of plasma troponin I testing during assessment of patients presenting to the ED after syncope.  

Methods: This is a retrospective cohort study being conducted at a single adult tertiary referral hospital. All adult patients presenting after syncope during a 3 year period from 1 January 2014 through 31 December 2016 are included. Patients were eligible for inclusion if ‘faint’, ‘syncope’ or ‘collapse’ was documented in triage notes or if diagnosed with ICD R55 (collapse or syncope) on admission or discharge. Patients were excluded if the syncopal episode was in the setting of seizure, severe trauma, change in baseline mental status and drug or alcohol intoxication. Troponin I, baseline demographics, vital signs, relevant clinical variables, length of stay and departure status were extracted using an explicit chart review.

Results: There were 3334 patients that presented with syncope during the study period and 1700 patients who had a troponin recorded eligible for inclusion in this study. Analysis to date reports on 215 patients with a mean age of 69.9 (16.0) years and 128 (59.5%) were male. Troponin was positive in 39 (17.2%) of patients. A history of structural heart disease (adjusted odds ratio 5.3; 95% CI: 2.1-13.3; p<0.01) and a presenting complaint of chest pain (adjusted OR 3.9; 95% CI: 1.4-11.3; p=0.01) were independently associated with an elevated troponin result. However, in patients without structural heart disease or chest pain, troponin was positive among 13 (8.5%) of patients.

Discussion: Troponin appears to be a useful investigation in the emergency department for assessment of patients with syncope. History and examination features cannot confidently rule out patients at high risk of adverse events. Ongoing analysis of the full sample size may inform high-risk variables associated with syncope and complete results will be presented. 


Claire STARK (Melbourne, Australia), De Villiers SMIT, Biswadev MITRA
11:00 - 11:05 #11281 - Effects of the BLS/AED course on self-efficacy levels of preclinical medical students.
Effects of the BLS/AED course on self-efficacy levels of preclinical medical students.

Background: Sudden cardiac arrest is one of the leading causes of death in Europe, with 84 cases per 100,000 inhabitants a year. Once cardiac arrest has occurred, early initiation of CPR and early defibrillation depends on bystanders and can lead to survival rates as high as 50-70%. This is a challenging activity that requires high levels of self-efficacy from the bystanders. In the field of cognitive theory, the term self-efficacy describes the way people choose to react during stressful situations - whether they decide to initiate challenging activities, which indicates high levels of self-efficacy, or they avoid implicating in such an activity, which correlates with low self-efficacy levels. Intervening in an incident of cardiac arrest is quite stressful and challenging. Training in CPR should include teaching techniques that ensure good knowledge retention and increase of self-efficacy.

Methods: Preclinical 3rd year medical students, in our University, participate compulsory in the BLS course, having no prior training in resuscitation. The course is organized according to the ERC regulations, including demonstrations and hands-on practice in groups, based on low-fidelity simulation scenarios. Participants are evaluated using continuous assessment. The 132 students that participated at the past year’s courses, were asked to complete an anonymous self-assessment questionnaire prior and immediately after their training. The questionnaire was designed using the Bandura’s “Guide for Self-efficacy Tests” and was modified using the Visual Analogue Scale. The questions had the form “I feel…” and included all basic steps of the BLS sequence: 1.Approach with care 2.Check for response 3.Check for normal breathing 4.Call the emergency services 5.Start chest compressions 6.Use an AED. The answers had the form: Not confident (0%) - Somewhat confident (25%) - Confident (50%) - Very confident (75%) - Extremely confident (100%) and had a colorized symbol according to the level of confidence represented, from blue – not confident to red – extremely confident.

Results: All 132 participants completed successfully the course, according to the continuous assessment performed by ERC certified instructors. The questionnaires analysis revealed enhancement of the self-efficacy levels in all steps of the algorithm after the course. The highest variation concerned the AED utilization with 89% feeling less than 50% confident prior to the session and 3% after the course. Another interesting finding was that even after the session, 30% of the students felt less than 75% confident to use an AED or to recognize a non-breathing victim.

Conclusion: Recognition of a non-breathing victim and AED use are regarded as the most challenging steps of the algorithm. The simulation-based hands-on BLS/AED course enhanced self-efficacy levels of preclinical medical students, implying that such courses can lead to more frequent initiation of the CPR algorithm during cardiac arrest events.


Anastasia SPARTINOU (HERAKLION, Greece), Vlasios KARAGEORGOS, Konstantinos SOROKOS, Christos NIKOLAROS, Eleftherios ANDRIANAKIS, Tzaneti ARIADNI, Dimitrios KOUVIDAKIS, Emmanouil KOLTSAKIS, Othon FRAIDAKIS, Alexandra PAPAIOANNOU
E-Poster Area

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PH6 - S2
10:45 - 11:05

E-Poster Highlight Session 6 - Screen 2

10:45 - 10:50 #10831 - How do triage nurses improve pain management in an Emergency Department?
How do triage nurses improve pain management in an Emergency Department?

Introduction 

Quick and optimal management of pain is not only a daily challenge in the Emergency Department (ED), but also a quality marker who makes medical care easier. A nurse-initiated protocol for pain by triage nurses has been introduced in our ED and lets nurses administrate Acetaminophen starting at the entrance.

Methods

We present here an observational, monocentric and retrospective study led in the ED of an urban teaching hospital in France. In June 2015, we included during 48 hours all adult patients consulting in our ED. A total of 240 patients were included for statistical analysis.

Results

Pain scale was assessed in 89% (CI95%=[85-92]) of all patients. The majority of patients who were not evaluated by the triage nurse (11%),) were described as not evaluable for unclear reasons. 152 patients (63%, CI95%: [57-59]) declared having pain at the entrance of the ED. Mean declared Visual Analog Scale at the entrance was 4.8±1.7. Numeric pain scale was mostly used (88%). Only 15% of painful patients benefited of an analgesic according to the pre-established protocol. 43% benefited of second-line treatment (i.e medically prescribed analgesia) and 42% (CI95%: [34-50]) did not receive any analgesic despite the pain they first reported at admission. Only 1% of patients refused analgesics when proposed.

Conclusion

An initial assessment was made by the triage nurse in the large majority (89%) of patients of this study. Around two third (63%) declared having pain but only a half of them (48%) received treatment (vs 38% in a national cohort study in 2010). Meanwhile, initial assessment by the triage nurse is now routine in our ED, few protocoled analgesic administration is proposed. Although pain assessment and management are recognized as quality indicators in an ED and inscribed in a national plan (2013-2017), pain remains insufficiently treated and protocols delegating (to triage nurses) non-opioid analgesics or even narcotics are probably needed.


Eve SCHNELL, Sarah UGÉ (Strasbourg), Pierre TRAN BA LOC, Clément BARBET, Elena Laura LEMAITRE, Claire KAM, Pierrick LE BORGNE, Pascal BILBAULT
10:50 - 10:55 #11110 - Developing a risk adjusted indicator for EMS pain management.
Developing a risk adjusted indicator for EMS pain management.

Background

The Pre-hospital outcomes for evidence based evaluation (PhOEBE) project is a 5 year research programme which aims to develop risk adjusted, patient focused performance and quality indicators for EMS. Consensus work identified a small number of potential indicators for further development. One high priority topic identified was pain management. We have explored the features of EMS pain management information and constructed a risk adjusted statistical model to measure mean reduction in pain in the EMS population.

Methods

We retrieved the computer aided dispatch and on scene electronic patient records for all 999 calls to one ambulance service in England for 6 months in 2013. We excluded patients who were managed by telephone advice, were under 2 years of age, died at scene or were unconscious. For included cases we conducted descriptive analyses of a range of variables including number of pain scores measures, age, sex, condition type and pre-hospital time. We then measured the correlation of these factors with reduction in pain score. Finally we constructed a multivariable linear model as a risk adjusted indicator of pain reduction.

Results

After exclusions 167,264 patient incidents were included. 27.7% had no pain score recorded, 23.7% had 1 score recorded and 48.6% more than one score. 35,749 patients (21.45%) had an initial pain score of ≤5 and 25.7% of these did not have a second score recorded. Cases were classified by conditions where pain may be expected or not expected. Of pain expected cases 23% had a pain score of 0 compared to 76.3% where it was not expected. Change in pain score was correlated with first pain score, age, total prehospital time, gender (male) and condition type. All of these variables were included in the final multivariable model with the specific conditions cardiac chest pain, trauma/injury and headache included.

Conclusions

Management of pain in the pre-hospital phase of care is an important outcome to patients. Our analyses have shown that around a quarter of patients have no pain score recorded and half have more than one pain score recorded. A number of patient characteristics are associated with mean reduction in pain score demonstrating that change in pain score alone is not a reliable indicator of clinical care. The risk adjusted indicator developed has the potential to be a more robust measure of EMS pain management that can more usefully used to monitor performance over time in a heterogeneous and changing population of patients.


Richard JACQUES, Janette TURNER (Sheffield, United Kingdom), Joanne COSTER, Niro SIRIWARDENA
10:55 - 11:00 #11654 - Not “Nonspesific Viral Myositis”, It is “Influenza Myositis”; Evaluation of 20 Cases with Clinical and Laboratory Findings.
Not “Nonspesific Viral Myositis”, It is “Influenza Myositis”; Evaluation of 20 Cases with Clinical and Laboratory Findings.

Background & Aim:

Benign acute childhood myositis (BACM) is a self-limited illness that occurs during epidemics of influenza. It is characterized by leg pain and weakness with an isolated laboratory finding of elevated serum creatine kinase (CK).

Here we report 20 previously healthy patients who were admitted to our emergency (ED) department after developing myositis during/following the influenza-like illness.

Methods:

Prospective, observational, case series conducted at an urban, academic ED during two influenza season (January-March 2016-January-March 2017). Demographic characteristics clinical findings, laboratory, serological features and outcomes of the patients were evaluated. Serological evaluation tests were also taken for possible etiology of viral infections from patients identified as having BACM. A nasopharyngeal aspirate (NPA) was taken from 20 patients for testing.

Results:

A total of 20 children were included. The mean age was 7.96 (SD ±3.54) years and 16 (80%) were male. The most common symptoms were leg pain (95%), anorexia (65%) and sore throat (50%). No patient had abnormal neurological findings, hematuria, or developed renal failure. The mean CK level at presentation was 3804 IU/L (range, 1634–8644 IU/L). Serological tests was performed for 20 patients and 14 (70%) influenza [influenza A and B were 3 (15%), 11 (55%), respectively], 3 (15%) rhinovirus, 2 (10%) RSV agents were detected and one was negative. Five patients (23.8%) with BACM were admitted to the ward and one of them developed rhabdomyolysis. The rate of admission was higher in influenza A myositis when compared to influenza B (66.8% and 18%, respectively). Patient with rhabdomyolysis had influenza A myositis too. All patients discharged with a good outcome, and full recovery was achieved within 24 hours to 7 days.

Conclusion:

BACM is a predominantly benign disease and recovers completely. It may occur in epidemics mainly in the winter season. Although, it has been described as nonspecific viral myositis, our results demonstrated  that most of them had influenza myositis and influenza A  had more severe clinical course than B. 


Caner TURAN (ISTANBUL, Turkey), Gulsum KESKIN, Ali YURTSEVEN, Candan CICEK, Eylem Ulas SAZ
11:00 - 11:05 #11812 - Proper allocation of patients in hospitals after Mass Casualty Incident – problem to solve.
Proper allocation of patients in hospitals after Mass Casualty Incident – problem to solve.

Background

Worldwide, mobile Information and Communication Technologies (ICT) have been used in prehospital emergency care and emergency and disaster medicine. The use of the ICT in routine emergency care does not raise any concerns, but special application used in mass casualty incidents and disasters is still being discussed in Poland. Today we witness a lack of cooperation between the pre-hospital emergency and hospital ICT systems. However, following the computerization of hospitals and emergency departments, there is a new opportunity to integrate both systems.

Study

The main problem during mass casualty incidents is how to properly allocate patients in hospitals. Information coming from the scene of the incident is insufficient to make the right decision. What's more, information transfer from hospitals and information about available ambulances to the Command and Control Center is the insufficient, too. Only once you link and process these three pieces of information will you be able  to make  the right decisions at any time. The development of special model of allocation patients based on ICT solutions, is the aim of this study.

Methods

The study was based on the analyses of the local EMS database (Cracow Dispatch Center operation area) and simulations of mass casualty incidents (MCI) during “sand table drill”. The same MCI, the first, with ICT support, the second without it. The study measured the following aspects: triage on site, decision‐making model, effectiveness of EMS, information management, and criteria for deciding on a patient transport model and allocation in the hospitals.

A proper allocation of the injured was the case of the study. The exercise  involved  seventy injured (25 red code, 30 yellow code, 15 green code), local emergency departments and trauma center, 25 ambulances, dispatch center and external support (ambulances and hospitals). We wanted to know how we could use the EMS resources and hospitals with and without ICT support.

Results

Results after two the “sand table drill” exercises were completely different. The same database of  the seventy victims, the same scenario, but a different type of disaster management without/with the ICT support were used. Use of the potential of ICT support was changing the way decision-making. The victims' allocation was more accurate and more accurately used the capacity of hospitals.

Conclusion

The use of ICT improves the efficiency of allocation of the injured in hospitals. The monitored emergency medical care has proved greater efficiency of decision making with the ICT support than the traditional one.  The results allow to define new directions for the development of intelligent Command Support Systems for emergency management.


Arkadiusz TRZOS (Krakow, Poland), Katarzyna DŁUGOSZ
E-Poster Area

"Wednesday 27 September"

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PH6 - S3
10:45 - 11:05

E-Poster Highlight Session 6 - Screen 3

10:45 - 10:50 #10597 - The association between impaired cognition and adverse outcome in older patients presenting to the emergency department with minor trauma; the APOP study.
The association between impaired cognition and adverse outcome in older patients presenting to the emergency department with minor trauma; the APOP study.

Title: The association between impaired cognition and adverse outcome in older patients presenting to the emergency department with minor trauma; the APOP study.

Authors: B.C.M. van den Berg*; MsC, J.A. Lucke*; MD, J. de Gelder; MD, C. Heringhaus; MD, B. de Groot; MD, PHD, S.P. Mooijaart; MD, PHD.

Introduction: A large number of older patients is discharged from the ED with minor trauma. Cognitive impairment may have a large impact on independent functioning, even in the case of minor trauma. The aim of this study was to investigate the impact of impaired cognition on functional status after 90 days in older minor trauma patients visiting the ED.

Methods: Analysis of the collected data from the APOP study (a prospective cohort study) of patients aged 70 years or older, presented to the ED. Cognition was measured using the 6CIT, using a cut-off of ≥11 as the definition of impaired cognition. Primary outcome was 1-point decrease in KATZ-ADL, new institutionalization or mortality after 90 days. The association between cognition and adverse outcomes was calculated using multivariable regression analysis.

Results: In this study, we included 125 (12.5%) of the 995 elderly patients who presented to the ED and were discharged home after a minor trauma. 30 (24%) of the patients with minor trauma had impaired cognition. In 13 (13.6%, 95% CI 7.8-19.4) patients with normal cognition and a minor trauma, there is functional decline, in comparison to 9 (30%, 95% CI 16.3-43.7) of the patients with impaired cognition (p = 0.004). These patients were four times more likely to have functional deterioration in comparison to an older patient with normal cognition independent of age, gender and educational level (OR 4.15, 95% CI 1.36-12.7). Injury type or location of a fracture were not associated with functional decline (p = 0.590).

Conclusion: Cognition is an independent predictor of functional decline. A patient aged 70 years and older with impaired cognition is 4 times more likely to suffer functional decline after minor trauma in comparison to a patient with normal cognition. On early recognition of this group at risk, additional information, preventive measures, care and support at home can be provided.

*authors contributed equally. 


Bianca C.m. VAN DEN BERG (Leiden, The Netherlands), Jacintha A. LUCKE, Jelle DE GELDER, Christian HERINGHAUS, Bas DE GROOT, S.p. MOOIJAART
10:50 - 10:55 #10983 - Diagnostic yield of CT and US evaluation for acute abdomen in a high-volume emergency department.
Diagnostic yield of CT and US evaluation for acute abdomen in a high-volume emergency department.

Background: Emergency medicine as a new specialty has been introduced in Finland during the recent years. Along with this change, there is a trend towards “one-stop-shop”-type of emergency admissions, aiming at a specific diagnosis on the first visit. This may potentially increase unwarranted imaging. Hence, we wanted to evaluate the diagnostic yield of abdominal imaging at emergency setting.

Material and methods: Consecutive patients admitted to a high-volume, collaborative emergency department (ED) undergoing either abdominal computed tomography (CT) or ultrasonography (US) during a one-year study period (1.1.-31.12.2016) were included in the study. Gravid women and patients requiring urinary tract-related imaging were excluded. Patient demographics, diagnoses (ICD-10 classification) and radiological studies were retrieved from hospital records. Based on the diagnostic distribution and performed radiological studies, we evaluated whether these studies were appropriate or not.

Results: Out of a total of 88,481 ED admissions, 3,508 patients (4.0%; median age 61 years, range 0-101 years; 52% female) underwent either abdominal CT or US examinations (n=4,058) and were thus included in the study. A total of 2,257 CT (56%) and 1,801 US (44%) studies were performed. Contrast-enhanced CT (n=1,923, 56%) was preferred over non-contrast-CT (n=334, 8.2%), and upper abdominal US (n=815, 20%) was the most often used of US modalities. During the study, 8.2% (n=286) of the patients were readmitted to ED with a need of a new radiological examination (range 1-6 studies/patient), and in 5.7% of emergency accesses (n=201) more than one radiological study was required to reach diagnosis.
Of the study patients, 37% were diagnosed to suffer from specific, acute diseases of the digestive system, most commonly acute appendicitis (7.0%), cholecystitis (6.8%), diverticulitis (6.4%), pancreatitis (3.1%) and intestinal obstruction or ileus (2.9%). In addition, pyelonephritis (2.6%) was among typical post-discharge diagnoses. However, one third (38%) of the patients were discharged without a specific diagnosis, even though they underwent emergency radiological imaging. Among the patients discharged without a specific diagnosis US, contrast-enhanced CT and non-contrast CT were performed in 46%, 34% and 26%, of the cases, respectively. 12% of patients were later diagnosed to suffer from extra-abdominal conditions; e.g. pneumonia was diagnosed in 1.7% of these patients.

Conclusions: Studies performed by a radiologist are often necessary to distinct an acute abdominal condition requiring surgical care from non-specific symptoms. However, we found that the percentage of patients discharged without a specific diagnosis after CT or US was quite high, 38%. Again, as extra-abdominal conditions in these patients were not uncommon, thorough clinical examination of the patient should still be at focus, prior to the use of costly and resource-intensive radiological studies.


Vuokko VAHTERA (Tampere, Finland), Leena SAARISTO, Mika UKKONEN, Johanna LAUKKARINEN, Irina RINTA-KIIKKA, Satu-Liisa PAUNIAHO
10:55 - 11:00 #11206 - Duplex sonography of extracranial vertebral arteries in patients with vertigo and suspected vertebrobasilar ischemia.
Duplex sonography of extracranial vertebral arteries in patients with vertigo and suspected vertebrobasilar ischemia.

Introduction

Vertebrobasilar ischemia accounts for 3-5% of vertigo presenting to emergency departments (EDs) and its diagnosis is challenging. The role of vertebral artery extracranial color-coded duplex sonography (VAECCS) in patients presenting with vertigo is unknown. The aim of this prospective study is to evaluate the diagnostic accuracy of a standardized VAECCS examination performed in patients presenting to ED with vertigo. 

Methods

Consecutive adult patients presenting to ED with vertigo and with suspected vertebrobasilar ischemia underwent VAECCS. VAECCS was performed by one of six sonographers according to a predefined protocol. The exam was considered abnormal when one of the following alterations were detected in V2 segments: flow not present in a segment or in all vertebral artery, flow detected but with an abnormal spectral waveform compared with opposite vertebral arteries (focal high peak systolic velocity, > 60cm/sec, high resistance pattern velocity, low velocity flow or post-stenotic flow pattern) or presence of flow inversion. Patients were followed up for 3 months and the final diagnosis established by a panel of expert composed by an emergency physician, a neurologist and an expert vestibologist based on all clinical and instrumental data except for VAECCS results. Acute cerebrovascular disease was diagnosed when an acute brain ischemic lesion congruent with symptoms was detected by neuroimaging.

Results

Among 126 patients included in the study, 28 (22%) were diagnosed with vertebrobasilar ischemia. VAECCS was abnormal in twenty patients (16% of all cases) and in 15 cases (75%) the final diagnosis was vertebrobasilar ischemia. In 106 (84% of all cases) patients VAECCS resulted normal and 13 of them (12%) had a final diagnosis of vertebrobasilar ischemia. The sensitivity and specificity of VAECCS were 54% and 95% respectively and detecting an abnormal flow pattern at VAECCS significantly increase the risk of vertebrobasilar ischemia (Odds ratio 21). The most important alterations related to vertebrobasilar ischemia were absence of flow and high resistance pattern velocity (odds ratio 9.3 and 22.7 respectively). 

Conclusion

VAECCS could be a useful bedside screening tool in patients presenting to ED with vertigo of suspected ischemic origin and predict vertebrobasilar ischemia. 


Sofia BIGIARINI, Peiman NAZERIAN, Laura TAURINO, Elisa CAPRETTI, Linda FALLAI, Stefano GRIFONI, Simone VANNI (Florence, Italy)
11:00 - 11:05 #11538 - An easier way; usg to detect nasal fracture in emergency department.
An easier way; usg to detect nasal fracture in emergency department.

Objective: The aim of our study is to compare ultrasonography and plain radiographs to evaluate the sensitivity and specificity of ultrasonography in the diagnosis of nasal fractures and availability of USG for detecting nasal fractures in the emergency department.

 Methods: Six hundred and thirty-six patients visited Dr. Lütfi Kırdar Kartal Training and Research Hospital Emergency Medicine Department with nasal trauma between 10.02.2015 and 01.09.2015 were included in this study. USG was performed by emergency medicine resident / specialist whom had advanced USG training beforehand and identified nasal fractures were recorded. Patients consulted to Ear, Nose and Throat (ENT) specialist with lateral nasal radiographs for confirmation. Nasal fracture was determined by examination of ENT specialists. The sensitivity, specificity, positive predictive value, negative predictive values of ultrasonography and plain radiographs were determined.

Results:

Compared with ENT examination in detecting the nasal fractures USG sensitivity was 97.8%, specificity 100%, positive predictive value was 100% and negative predictive value was 98.8%, and the plain radiography sensitivity 80.3%, specificity 99.5%, positive predictive value 98.9%, negative predictive value was 90%. Under the age of 5 years old children, in detecting the nasal fracture, negative predictive value of USG was 97.2%. The elderly population over age 65, in detecting the nasal fracture; sensitivity, specificity, positive and negative predictive value of USG was 100%.

 Conclusion: On the diagnosis of nasal fracture it was found that USG is superior to plain radiographs. It’s harmless, fast, easy to apply with ability to make the right diagnosis.


Can UNER (Istanbul, Turkey), Eren GOKDAG, Fatma Sari DOGAN, Ozlem GUNEYSEL
E-Poster Area

"Wednesday 27 September"

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PH6 - S5
10:45 - 11:05

E-Poster Highlight Session 6 - Screen 5

10:45 - 10:50 #11324 - The Icatibant Outcome Survey: Treatment of laryngeal hereditary angioedema attacks.
The Icatibant Outcome Survey: Treatment of laryngeal hereditary angioedema attacks.

Background: Laryngeal attacks may be fatal without prompt and effective treatment. Icatibant is a bradykinin B2 receptor antagonist used to treat hereditary angioedema (HAE) type I/II attacks in adults. We analysed characteristics and outcomes of icatibant-treated laryngeal HAE attacks in a real-world setting.

Methods: The Icatibant Outcome Survey (IOS; Shire, Zug, Switzerland [NCT01034969]) is a prospective, international observational study that monitors the safety and effectiveness of icatibant treatment. Retrospective descriptive analyses of laryngeal HAE type I/II attacks were performed (July 2009-February 2017).

Results: Of 4541 icatibant-treated HAE type I/II attacks (517 patients), 239 were laryngeal (120 patients; 62.5% female): 170 (71.1%) attacks affected the larynx only and 69 (28.9%) multiple sites. Of evaluable attacks, 162/214 (75.7%) and 52/214 (24.3%) were treated with self- and healthcare professional (HCP)-administered icatibant, respectively. Of the 52 attacks treated with HCP-administered icatibant, emergency room physicians administered treatment for 10 (19.2%) attacks. 127/207 (61.4%) attacks were severe/very severe and 63/239 (26.4%) were in patients on long-term prophylaxis (LTP). Of 51 icatibant-treated attacks in patients receiving LTP, androgens were LTP in 33 (64.7%) attacks and C1 inhibitor (C1 INH) was LTP in 7 (13.7%) attacks. 41/239 (17.2%) attacks were treated with concomitant or rescue medication. 216/235 (91.9%) attacks did not require C1 INH rescue medication, of these 194/216 (89.8%) attacks received one icatibant injection,  17/216 (7.9%) received two icatibant injections and 5 (2.3%) received 3 icatibant injections. C1 INH was used as a rescue medication in 19 attacks treated with one icatibant injection. Median (IQR) time to treatment was 1.0 (0.3, 3.5) h (110 attacks), median (IQR) time to resolution was 6.0 (2.0, 23.3) h (109 attacks), and median (IQR) attack duration was 8.8 (3.7, 24.0) h (92 attacks). For 6 evaluable attacks treated with a second injection, the median (IQR) time between first and second injection was 5.5 (1.3, 10.0) h; for 5 evaluable attacks, median (IQR) time from second injection to symptom resolution was 4.0 (2.0, 6.8) h.

Conclusions: Most laryngeal HAE type I/II attacks were successfully treated with a single, self-administered, icatibant injection; a second injection or other medication was only needed in a minority of cases. Patients on LTP may experience breakthrough laryngeal attacks resolved with icatibant. Emergency physician administration of icatibant was reported in a minority of HAE laryngeal attacks.


Andrea ZANICHELLI (Milano, Italy), Hilary J. LONGHURST, Werner ABERER, Laurence BOUILLET, Teresa CABALLERO, Marcus MAURER, Anette BYGUM, Anete S. GRUMACH, Christelle POMMIE, Irmgard ANDRESEN
10:50 - 10:55 #11691 - Ethyl pyruvate reverses development of pseudomonas aeruginosa pneumonia during sepsis-induced Immunosuppression.
Ethyl pyruvate reverses development of pseudomonas aeruginosa pneumonia during sepsis-induced Immunosuppression.

Sepsis is characterized by an innate immune response and the following immune dysfunction which can increase the emergence of secondary infections. Ethyl pyruvate (EP) has multiple immunoregulation functions in several serious illness models, such as burn injury, severe sepsis and acute respiratory syndrome. However, little data was shown the effect of EP administration to the immunosuppression post-CLP and the following secondary infection. Using a model of cecal ligation and puncture (CLP) infected by Pseudomonas aeruginosa (PA), we characterized the immune response of two-hit model of sepsis. We assessed the survival rate, lung damage and lung bacterial clearance in vehicle or EP treatment group to demonstrate the lung response to pseudomonas aeruginosa of septic mice and the effects after EP treatment. Then cytokines, apoptosis of splenic immune cells and Foxp3 expression on splenic regulatory T cells (Tregs) were studied to demonstrate the mechanisms of EP administration on two-hit mice. We found that the susceptibility of septic mice to Secondary Pseudomonas aeruginosa pneumonia could be down-regulated by ethyl pyruvate treatment and the protective effects of EP may via altering the expression of cytokines, inhibiting the function of Tregs and relieving the apoptosis of splenic immune cells. The “immune paralysis” post-sepsis still remains a rigorous challenge for curing sepsis, our study may aid in the development of new therapeutic strategies to this problem.


Chen WEI, Lu ZHONG-QIU (Wenzhou, China)
10:55 - 11:00 #11717 - Frequency of illicit drugs among adolescents presenting to the emergency department.
Frequency of illicit drugs among adolescents presenting to the emergency department.

 

Background and Objectives: One of the most common, and most dangerous, of adolescents’ risky behaviors is using illicit drugs in many countries. Drug-related visits to emergency departments (ED) have continued to increase in Turkey. We aimed to determine the frequency of substance abuse among adolescents who presented to our ED. We also tried to identify potentially relevant biological, psychological and socio economic characteristics of the adolescents. 

Methods: We conducted a retrospective study of all patients, aged 13–18 years, presenting to our emergency department (ED) with complaints related to recreational drug use and having a positive urine drug screening from January, 2013 to December 2015. To minimize the missing data, a telephone interview was done by the first author. Baseline demographic data (age, gender) and clinical data (admission date, cause of presentation) were obtained.

Results: During the study period there were 10350 adolescent visits. Urine toxicology screen was positive for illicit drugs in 83 (0.8%) patients. The rate of substance users to total adolescent admissions by years were respectively 17 / 2837 (%0.6) in 2013, 27/3476 (%0.8) in 2014, 4037 and 39 (%1) in 2015. Male adolescents were (60%) more likely than their female counterparts to use illicit drugs. The median age was 16 years in our study. Majority of substance users (64%) were more likely to present by neuropsychiatric complaint. Amphetamine (60%) was the most commonly used substance in our cohort, followed by cannabis (25%), benzodiazepine (8%), synthetic cannabinoid (4%) and opiate (3%). The frequency amphetamine use in female adolescents was 74%. Telephone interview was performed only in 37(46%) parents.  Rate of cigarette and alcohol use in this adolescent group was respectively 95% and 62%. This group also had some specific features such as smoker parents (92%), low income (62%) and single‐parent family (52%). Multi organ failure developed in a boy and "Ecstasy"-related fatality occurred.

Conclusion: Since the high rate of illicit drug use among youth has been steadily increasing adolescent substance use needs to be identified and addressed as soon as possible.  The most common identified substance was amphetamine. 


Dr Ali YURTSEVEN (İzmir, Turkey), Caner TURAN, Eylem Ulas SAZ
11:00 - 11:05 #11820 - Acute exposure to air pollution and atrial fibrillation: the Emergency Department perspective.
Acute exposure to air pollution and atrial fibrillation: the Emergency Department perspective.

Acute exposure to air pollution and atrial fibrillation: the Emergency Department perspective

Introduction and objective:

Several studies suggest that exposure to air pollution may leads to atrial fibrillation (AF) onset. However the association of AF onset to particulate matter (PM) remains still unclear. On the other hand, AF is the most common cardiac arrhytmia in clinical practice especially in the Emergency Department (ED).

Methods:

We performed a retrospective study on AF admitted to our ED from Jan 2011 until Dec 2016. The association of AF onset was correlated with air particulate matter PM (PM 10 and PM2.5) levels. Incidence of cases was associated with PM concentration levels on the day of onset (lag 0-day) and on the next 3-days moving levels (lag 3-days) following PM increase. Veneto Regional Agency for Prevention and Environmental Protection (ARPAV) provided PM air levels were provided from local monitoring data, classified accordingly with EU air quality standards for pollutants in air (25 µg/m3 for PM2.5 and 50 µg/m3 for PM10).

Results:

826 AF were admitted to the ED in the study period: 376 (45.5%) were male (mean age 70 years; range: 21-98) and 450 (54.5%) were female (mean age 77 years; range: 36-102). We did not observe any difference when comparing AF incidence with PM10 levels. PM2.5 air concentration over the EU safety limits revealed to be associated with a higher incidence of AF (+32%) compared to AF cases admitted on the within the EU standards PM2.5 level days. Gender distribution was similar to the study population one (M 43% vs F 57%) with an older female population (M 70 years vs F 77 years). Lag 0-day exposure to high PM2.5 accounted to 60% of the cases with a slight increase in the male group (M 66% vs F 60%). Lag 3-days exposure accounted for the remaining AF cases (M 34%, F 40%).

Conclusions:

AF, the most common cardiac arrhytmia, increases the risk of stroke and death. Only few studies, in the recent years, reported association between air pollution and AF. Our data show an association of exposure to PM2.5 concentration exceeding the EU safety threshold and AF incidence. It is likely that AF, associated with stroke and cardiovascular disease, contributes to the adverse effects of air pollution observed in clinical studies.

 


Massimo ZANNONI (VERONA, Italy), Alberto RIGATELLI, Gianni TURCATO, Lucia ANTOLINI, Chiara BOVO, Giorgio RICCI, Mariano BELLONI
E-Poster Area
11:10

"Wednesday 27 September"

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A42
11:10 - 12:40

Toxicology

Moderators: Kurt ANSEEUW (Medical doctor) (Antwerp, Belgium), Pr Bruno MEGARBANE (Professor, head of the department) (Paris, France)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
11:10 - 11:40 Paracetamol poisoning: basics for EP, novel techniques and upcoming research. Davide LONATI (MD, Clinical Toxicologist, Invited speaker) (Speaker, PAVIA, Italy)
11:40 - 12:10 Novel phycho-active substances in the ED. Kurt ANSEEUW (Medical doctor) (Speaker, Antwerp, Belgium)
12:10 - 12:40 ECMO for treatment of cardiotoxic intoxications. Pr Bruno MEGARBANE (Professor, head of the department) (Speaker, Paris, France)
Trianti Hall

"Wednesday 27 September"

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B42
11:10 - 12:40

EUSEM journal club

Moderators: Pr Rick BODY (Professor of Emergency Medicine) (Manchester), Senad TABAKOVIC (Medical director emergency department) (Zürich, Switzerland)
Coordinator: Senad TABAKOVIC (Coordinator, Zürich, Switzerland)
Speakers: Pr Rick BODY (Professor of Emergency Medicine) (Speaker, Manchester), Colin GRAHAM (Director and Professor of Emergency Medicine) (Speaker, Hong Kong, Hong Kong), Youri YORDANOV (Médecin) (Speaker, Paris, France)
11:10 - 11:40 - Nine papers that question current practice.
11:40 - 12:10 - The top 3 papers in Emergency Medicine, 2016-17.
12:10 - 12:40 - How to bring science to the people.
Mitropoulos

"Wednesday 27 September"

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C42
11:10 - 12:40

Ethical and legal issues in EM (How To)
Ethical dilemmas in the ED

Moderators: Helen ASKITOPOULOU (Chair Ethics Committee) (Heraklion, Greece), Robert LEACH (Head of Dept.) (BRUXELLES, Belgium)
Coordinator: Pr Rick BODY (Coordinator, Manchester)
11:10 - 11:40 We can do almost everything, but should we do it? Marc SABBE (Medical staff member) (Speaker, Leuven, Belgium)
11:40 - 12:10 Family-witnessed resuscitation in the Emergency Department. Helen ASKITOPOULOU (Chair Ethics Committee) (Speaker, Heraklion, Greece)
12:10 - 12:40 Withholding and withdrawing life sustaining treatments in the ED. Bernard FOEX (Consultant in Emergency Medicine and Critical Care) (Speaker, Manchester, United Kingdom)
Banqueting Hall

"Wednesday 27 September"

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F42
11:10 - 12:40

Free Papers Session 13

Moderators: Youri YORDANOV (Médecin) (Paris, France), Anastasia ZIGOURA (Greece)
11:10 - 11:20 #10860 - OP109 Risk factors helping to decide for whom to isolate, when suffering from acute gastroenteritis.
OP109 Risk factors helping to decide for whom to isolate, when suffering from acute gastroenteritis.

Title: Risk factors helping to decide for whom to isolate, when suffering from acute gastroenteritis.

Background:

Isolation of contagious patients with gastroenteritis requires more caregiver time and delays the examination, start of treatment and reduces the level of care. But isolation is, especially in an emergency department (ED) with high patient flow, necessary to prevent spreading of communicable diseases.

The aim of the study was to identify risk factors helping to identify patients with acute gastroenteritis infected with Norovirus or toxic Clostridium difficile requiring isolation, in order to choose the right room before or at the patients’ arrival.

 

Method:

At four regional hospitals all patients, acutely admitted due to acute gastroenteritis, were interviewed and stool samples analyzed for Norovirus, toxic Clostridium difficile and pathogenic gut bacteria. Vital parameter at admission and anamnestic factors (gastrointestinal symptoms before admission, travel history, previous and recent treatment with antibiotics) were obtained.

 

Results:

191 patients were included, 54 patients were not able to deliver any fecal sample. 81 samples were negative, 22 samples were positive for pathogenic gut bacteria, 32 were positive for infectious gastroenteritis (Norovirus or toxic Clostridium difficile) and 2 were positive for infectious gastroenteritis and pathogenic gut bacteria (Campylobacter one combined with norovirus, once combined with toxic Clostridium difficile).

The following risk factors were found significant for Norovirus: a sub febrile temperature (37.5 -38.5 Celsius OR 3.5; 95% CI 1.1 -11.6), length of diarrhea (more than three days OR 0.3; 95% CI 0.01- 0.3), length of vomiting (one day OR 4; 95% CI 1.2 – 13.2), number of vomiting’s (more than 10 on the day of symptom debut OR 6.9; 95% CI 1.7 – 28.1) and appearance of another patient infected with Norovirus with in the previous week (OR 4.3; 95% CI 1.4 - 12.7).

Mucus in stools was significant for toxic Clostridium difficile (OR 3.5; 95% CI 1.02 – 12.3) as well as previous treatment with antibiotics (completed cure one month before admission OR 15.5; 95% CI 3.4 – 71.2) and low pulse (<60/minute OR 7.8; 95% CI 1.5 – 40.2) as well as length of diarrhea (more than three days OR 4.9; 95% CI 1.1- 23.0).

 

Conclusion:

An algorithm to identify patient with infectious gastroenteritis will be developed by using the identified risk factors. As Norovirus and toxic Clostridium difficile can be significant in the same factor but with opposite meaning (length of diarrhea for Noro OR 0.3 and toxic Clostridium difficile OR 4.9) both factors may not be combined to one algorithm for infectious gastroenteritis.


Florence SKYUM, Vibeke ANDERSEN, Ming CHEN, Court PEDERSEN, Pr Christian Backer MOGENSEN (Aabenraa, Denmark)
11:20 - 11:30 #11603 - OP110 Socio-economic determinants of general practitioner consultation after emergencies visit.
OP110 Socio-economic determinants of general practitioner consultation after emergencies visit.

Introduction: Recent studies have demonstrated the existence of social inequalities in health and healthcare access worldwide. Having a general practitioner (GP) and a greater continuity of care is associated with decreased emergency department (ED) use at any age of life. Some studies have demonstrated that interventions aiming to enhance follow-up after ED visit are associated with a better healthcare continuity and a reduction of ulterior ED visits. But no data is available concerning quality of continuity of care after an ED visit.

Objectives: To identify the determinants of GP visit after an ED visit.

Method: We included all adult patients that have presented in an ED during a 7 days period. Patients admitted to the hospital were excluded.  Collected data included socio-economic and medical characteristics of patients as well as GP visit in the month following ED visit. A mutivariate logistic regression has been used to identify the determinants of GP consultation.

Results: The study included 243 patients among which, 122 (50%) consulted their GP in the month following ED visit. Among all GPs, 75 (31%) were located in an area of less than 2km from the ED. Older age (p=0,001), poor self-reported health status (p=0,001), self-reported functional limitation (p=0,020), good perceived accessibility of GP (p=0,001) and prescription of work stoppage (p=0,029) were associated with an increased frequency of GP visit. In multivariate analysis, only age (aOR=1.03), poor self-reported health status (aOR=2.95) and prescription of work stoppage (aOR=2.95) were associated with increased likelihood of GP consult. Only 57 patients who had consulted their GP brought the medical report from ED visit.

Conclusion: Our study showed that half of patients consulted their GP after an ED visit and about 30% of GPs were located in a 2km area. Primary care use was partly explained by age, poor reported health status and prescription of work stoppage. 


Julie ROTIVAL, Diane NAOURI, Youri YORDANOV (Paris), Erwan DEBUC, Dominique PATERON
11:30 - 11:40 #10964 - OP111 TTUHSC EP Intubation Results from the National Emergency Airway Registry (NEAR).
OP111 TTUHSC EP Intubation Results from the National Emergency Airway Registry (NEAR).

Introduction
We have joined the National Emergency Airway Registry (NEAR) which is a multicenter registry that has compiled data about intubations conducted at academic teaching institutions since the 1990s. Between 2002 and 2012 the registry recorded 17,583 intubations at 13 facilities. A new data collection cycle began in January 2016 and our institution joined in February 2016.
Objectives
The goal of this study was to analyze the data for our institution and compare it to the published national registry data for 2002-2012.
Materials & Methods
We analyzed the data in the NEAR registry for our institution for February 2016 to February 2017. Using descriptive statistics we examined the indications for intubation, operators, success rate, and adverse event rates for emergency department intubations at our facility and compared them to published NEAR data.
Results
Over 12 months we reported 380 intubations to NEAR. About 2/3rds of intubations were indicated for medical emergencies with the remaining 1/3 being done in trauma cases. Our overall first pass success rate was 84% which is on par with the published national rate. Resident physicians performed 95% of intubations while attendings performed the remaining 5%. Adverse events occurred in ~11% of intubation patients at our institution and events included vomiting, cardiac dysrhythmias, laryngospasm, hypoxia, and misplacement of the tube. This percentage is also similar to the published national average.  Small differences were seen in the induction agents used at our facility compared to national rates: etomidate 83%, ketamine 13%, propofol 3%, midazolam 1% vs 91%, 1%, 3.2 %, 1.4 % respectively. A more significant difference was found in the use of paralytic agents: we used rocuronium in 66% and succinylcholine in 34% of intubations requiring paralytics compared to the national rates of 23% for rocuronium and 75 % for succinylcholine.
Conclusions
Our data so far shows similar rates of first pass intubation success and adverse event rates when compared to the previous cycle NEAR data. The preference of paralytic agents at our institution appears to be the reverse of the national trends.  Continued monitoring will help us identify deficiencies in practice and opportunities for improving training and patient care.
References
1) Brown CA, Bair AE, Pallin DJ, et al. Techniques, success, and adverse events of emergency department adult intubations. Annals of Emergency Medicine. 2015. 65:363-370


Robert KILGO, Radosveta WELLS (El Paso, USA), Scott CRAWFORD, Sabrina TAYLOR, Michael TRAN, Brett TRULLENDER, Sam SNEAU, Stormy MONKS, Susan WATTS
11:40 - 11:50 #11906 - OP112 Trauma setting ‘can’t intubate, can’t oxygenate’ emergencies: European Trauma Course Austria instructors' perspective.
OP112 Trauma setting ‘can’t intubate, can’t oxygenate’ emergencies: European Trauma Course Austria instructors' perspective.

Purpose of the study: In trauma setting, difficult airway (DA) emergencies require prompt intervention, and may result in significant morbidity and mortality. Direct airway trauma, accompanied with cervical immobility, and tenuous haemodynamics further complicate decision-making proccess. An unanticipated DA often results in an adverse outcome if the concerned trauma physician is either not abreast with current guidelines or is not familiar with the use of variety of airway adjuncts. The Difficult Airway Society (DAS) guidelines provide framework for the management of the unanticipated DA, ending with the emergency ‘front-of-neck access’ (FONA) algorithm in the ‘can't intubate, can't oxygenate’ (CICO) scenario. In the 2015 DAS guidelines, ‘scalpel-bougie’ (SB) technique has been advocated, because it requires equipment readily available to most clinicians regardless of clinical setting. In addition, other techniques, such as needle cricothyroidotomy (CCT), are proposed, depending on individual experience, training, comfort of use, and case specifics. Recent scientific evidence regarding the technical and human factors superiority of one technique over another remains largely speculative. In our study we aimed to investigate European Trauma Course (ETC) instructors’ management preferences during CICO emergencies. Materials and methods: A total of 44 (69%) instructors, actively teaching on ETC in Austria throughout 2016, completed an online survey. The survey consisted of demographic data, and 13 open questions regarding DA management in CICO scenarios. Results: There were 29 (66%) male instructors, aged from 30 to 71 years (median 42). The majority of instructors were anesthetists (57%), followed by emergency physicians, and trauma surgeons in descending order. Nearly two thirds (73%) of responders were aware of protocolled FONA algorithms for the CICO scenarios, instituted in place of their own operating rooms. However, only half of them would consider these proposed institutional algorithms in real life CICO emergencies. Despite the 2015 DAS FONA algorithm guidelines, promoting SB technique, nearly half of our instructors are still in favor of a CCT technique. Our instructors expressed the strongest agreement with the statement that cannula techniques, when compared to surgical ones, potentially offer advantages from a human factors perspective, if supported by appropriate educational programs. Conclusions: Our results suggest our instructors have a strategy of utilizing well-practiced algorithms at a moment’s notice when faced with a critical trauma patient during the CICO scenarios. However, using a scalpel still remains a rare intervention for most of them. Directing resources towards demystification and better training in the scalpel techniques, may improve our instructors’ willingness of performing SB interventions. 


Ileana LULIC, Dr Dinka LULIC (Zagreb, Croatia), Florian TRUMMER, Adi DEIXLER, Katja KALAN USTAR, Christian SCHREIBER, Michael HÜPFL
11:50 - 12:00 #11422 - OP113 The correlation and prognostic value of high sTWEAK protein levels and ischemic area volume detected by diffusion weighted imaging in acute ischemic stroke patients.
OP113 The correlation and prognostic value of high sTWEAK protein levels and ischemic area volume detected by diffusion weighted imaging in acute ischemic stroke patients.

Background& Aim: Stroke is a leading cause of mortality and has a subsequent serious long-term disability among survivors. This study evaluated the relationship between sTWEAK (soluble Tumor necrosis factor-like weak inducer of apoptosis) protein levels and the lesion area measured in diffusion-weighted imaging (DWI) in acute ischemic stroke patients.

Patients and Methods: Forty-one patients with acute ischemic stroke and 41 control cases were included in the study. The age, sex, chronic illnesses, emergency department admission times, emergency department examinations, GCS and 7-day prognostic status of the patients were evaluated.

Results: The symptoms of stroke started within the first 3 hours in 32 (78%), between 4-6 hours in 6 (14.7%) and between 7-12 hours in 3 of the patients (7.3%). There was no difference between onset time of complaints, age, regular medication usage, medications, evaluation findings in emergency department, number of findings and GCS (p>0.05). However there were statistically significant differences between the number of findings noted during the emergency evaluation of patients, GCS and the ischemic area volumes measured in magnetic resonance imaging (MRI) (p=0.001, p=0.022, respectively). There was also a statistically significant difference in blood urea nitrogen, creatinine and the volume of ischemic area measured in MRI among the patients who died (19.5%) within the first 7 days and alive group (p=0.011, p=0.029, p=0.004, respectively). A statistically strong negative correlation between the ischemic area volume measured in the DWI and the GCS (r=-0.61), and intermediate positive correlation between BUN (r=0.40) and creatinine (r=0.36) were detected (p<0.05). There was a statistically significant difference in sTWEAK levels between stroke patients and healthy controls included into the study (p<0.001). sTWEAK levels of stroke patients were significantly higher than the healthy controls [AUC:0.86 (0.77-0.94); p<0.001] and the cut-off value was determined as 995.5pg/ml. This cut-off value for sTWEAK had a sensitivity of 80.5% and specificity of 82.5% with a positive predictive value of 82.5% and negative predictive value of 80.5%.

Conclusion: sTWEAK is a valuable marker for the diagnosis of acute stroke but is not significant in predicting early prognosis.


Ertan CÖMERTPAY, Nermin DINDAR BADEM, Sevilay VURAL (Yozgat, Turkey), Oğuz EROĞLU, Figen COŞKUN
12:00 - 12:10 #11532 - OP114 C - reactive protein as a prognosticator in non ST elevated myocardial infarction.
OP114 C - reactive protein as a prognosticator in non ST elevated myocardial infarction.

Introduction:

The inflammation is well known in the initiation and propagation of acute coronary syndrome. The aim of study was to assess the ability of C - reactive protein (CRP) to predict in hospital morbidity of patients with non ST elevated myocardial infarction (NSTEMI).

Methods:

It was an observational prospective study conducted in an emergency department (ED) during six months (July-December 2015). We included patients who met criteria of NSTEMI aged more than18 years. The prognosis was evaluated on the occurrence of myocardial infarction (MI) and hospitalization in cardiac intensive care unit (CICU) within 30 days.

Results:

We enrolled 89 patients. The mean age was 59 years. Sixty eight were males. Sixty seven percent of patients were smokers, 47% had hypertension, 33% diabetes, 13% dyslipidemia and 25% had coronary disease. A depressed ST segment was found in 11.2% of cases, inversed T wave in 10.1%, and left bundle bloc in 5%. The mean CRP of patients admitted to CICU was significantly higner than CRP of others (not admitted to CICU) with 35.54 ± 33.18 vs 13.36 ± 20.2 (p˂0.000). The mean CRP of patients with MI was significantly higner than CRP of others with 39.55 ± 27.39 vs 16.9 ± 29.38 (p˂0.000).

Conclusion:

CRP can be used as an indepedent factor to predict morbidity in patients with NSTEMI in emergency department.


Saloua AMRI, Najeh HAJJEM, Imene MEKKI (Tunis, Tunisia), Mohamed Walid MHAJBA
12:10 - 12:20 #11582 - OP115 suPAR improves risk prediction with national early warning score in acute medical patients.
OP115 suPAR improves risk prediction with national early warning score in acute medical patients.

Background

The national early warning score (NEWS) is a combined measure of vital signs and is used for triage in the ED. The NEWS is a strong short-term outcome predictor. However, patients with normal vital signs (low NEWS) may also be at risk of a negative outcome and thus have need for clinical attention. Soluble urokinase plasminogen activator receptor (suPAR) is an inflammatory biomarker that has been shown to be a strong marker of patient prognosis. Here, we aimed to investigate whether suPAR in combination with NEWS can improve risk prediction.

Methods

This study includes 17,312 patients admitted to the acute medical department, Copenhagen University Hospital Amager and Hvidovre, between 18 November 2013 and 30 September 2015. Patients were followed for 90 days via national registries. suPAR measurements and data on vital signs, admission NEWS, diagnoses, and vital status were combined for the index admission. Endpoints were in-hospital-, 30-day-, and 90-day mortality. Statistical analysis was carried out with Kruskal-Wallis test, multivariate Poisson regression analysis, and receiver operating characteristics (ROC) curve analysis.

 

Results

NEWS was available for 16,244 patients (93.8%) and ranged from 0-16. The majority of patients (59.7%) had a NEWS of 0-1. Median suPAR increased with NEWS (P<0.0001), and suPAR and NEWS were weakly positively correlated (Kendall’s tau-b 0.23, P<0.0001).

The frequency of patients who died increased with NEWS score (P<0.0001) for in-hospital-, 30-day-, and 90-day mortality. Furthermore, mortality rates for all endpoints increased with increasing NEWS group compared with patients with NEWS 0-1 in Poisson regression adjusted for age and sex.

The median suPAR level at the index admission was significantly higher in patients who died compared with patients who survived at all three endpoints (P<0.0001). High suPAR was significantly associated with increased mortality rates in all NEWS groups and for all endpoints, except for in-hospital mortality for patients with a NEWS of 6. The mortality rate ratio for a doubling in suPAR was highest for patients with NEWS 0-1.

ROC curve analyses were carried out for predicting in-hospital-, 30-day-, and 90-day mortality. The AUCs for all three endpoints were markedly improved when adding age and sex to the NEWS. The addition of suPAR further improved the prediction (P<0.0001). For in-hospital mortality, the AUC for NEWS alone was improved from 0.87 (95% CI, 0.85-0.88) to 0.92 (95% CI 0.91-0.92) after adding age, sex, and suPAR.

 

Conclusion

In this study of acute medical patients, we found that NEWS and suPAR were both strongly associated with risk of in-hospital-, 30-day-, and 90-day mortality and suPAR improved the predictive value of the NEWS. The suPAR level increased with increasing NEWS and there was a strong association between suPAR and mortality across NEWS scores; suPAR was a stronger predictor of mortality in patients with low NEWS scores. 


Line Jee Hartmann RASMUSSEN (HVIDOVRE, Denmark), Steen LADELUND, Thomas Huneck HAUPT, Gertrude ELLEKILDE, Jesper EUGEN-OLSEN, Ove ANDERSEN
12:20 - 12:30 #10903 - OP116 Comparison of point-of-care testing to conventional laboratory process in urban emergency department.
OP116 Comparison of point-of-care testing to conventional laboratory process in urban emergency department.

Background. The laboratory turn-around time for results from central laboratories (CL) can take over 60min compared to 10-15min with point-of-care bedside testing (POCT). However, many studies on POCT, focused on selected tests and limited patient populations, have suggested reduced length of stay (LOS). Many have also reported, where POCT strategy alone has not necessarily improved LOS or had effect on only certain group of patients.  

In this study, we hypothesized that POCT would reduce LOS in emergency department (ED) when compared to central laboratory testing and be a factor in patient discharge destination, home or hospital.

Methods. Single centre observational study was performed in random ED patients, excluding ambulatory and fast-track, at Jorvi, Helsinki University Central Hospital, Finland. Blood testing was performed either with POC instruments iSTAT (Abbott) for blood gases and chemistry panel, and PocH-100i (Roche) for full blood count, and Afinion (Alere) for CRP or at central laboratory or combination of both. Blood draw and POCTs were performed by experienced nurses. Time to blood draw, results availability, and disposition of patients either to home or hospital were captured and analysed by Mann-Whitney U test and a p value less than 0.05 considered as statistically significant. Patients with any missing data were eliminated from the analysis. This study was approved by local institutional ethics committee.

Results. During the four-week study period, 2618 patients underwent sample testing (POCT: n=726, central lab: n=1669; both n=726). The average time for blood draw after registration ranged from 1:12±0:56 to 1:30±1:16 hours and it did not depend on the method of laboratory testing. POCT provided results significantly faster than the other two methods of testing (mean±SD for POC 1:02±1:56, CL 2:31±3:18, Combined 3:18±3:36 hours, p<0.0001). The overall ED LOS was also reduced (POC 6:40±3:36, CL 8:05±4:59, Combined 8:13±5:17 hours, p<0.0001). The mean ED LOSs were not statistically significant when the patients were discharged to hospital/care unit (POC 7:33±2:10, CL 8:32±1:07, Combined 8:47±1:05 hours, p=ns), whereas the patients with POCT were discharged home at least 2 hours earlier than those who had testing done by other two methods (POC 5:58±1:18, CL 7:48±1:58, Combined 7:22±1:32 hours, p<0.0001). The percentages of patients discharged were: to home POC 16%, CL 50%, Combined 34% and to hospital: POC 10%, CL 56%, Combined 34%.

Conclusion. POCT shortened laboratory process significantly and made results available significantly faster than the central lab or combined testing, resulting in overall LOS reduction in ED. This also provides options to discharge patients home quicker than to hospital/care unit that may be delayed due to the need for additional diagnosis, or availability of hospital beds. Thus, with proper training and education to the ED care team, POCT can be used as an effective tool for managing patient flow in ED.


Veli-Pekka HARJOLA (Helsinki, Finland), Marika HOLMA-ERIKSSON, Meri KANKAANPÄÄ, Sami KAPANEN, Merja HEITTO, Sari BERGSTRÖM, Leila MUUKKONEN
12:30 - 12:40 #11036 - OP117 Evaluation of the accuracy of a clinical decision rule to rule out acute coronary syndrome and adequacy of coronary CT requests in emergency department.
OP117 Evaluation of the accuracy of a clinical decision rule to rule out acute coronary syndrome and adequacy of coronary CT requests in emergency department.

BACGROUND: Non-traumatic chest pain is a common presenting complaint among patients seeking care in the Emergency Department (ED). A substantial proportion of patients with chest pain are admitted for inpatient care in order to rule-out acute coronary syndrome (ACS) and only a small proportion had abnormal tests and lead to a change in management. These admissions and investigations in patients without ACS cause a substantial health care burden. At the same time, 2-4% of patients with ACS are erroneously discharged from the ED. The aim of this study is to assess the accuracy of the Diamond Forest clinical decision rule (CDR) to select candidates for coronary CT in patients with non-traumatic chest pain and suspicious of ACS and the adequacy of coronary CT requests in emergency department.

METHODS: We prospectively enrolled adults (age ≥18 years) who presented with chest pain at emergency department of Cruces University Hospital (a tertiary hospital with a cover population of 320,000 people) over 12 months. Physicians completed standardized data collection forms before diagnostic testing. The primary adjudicated outcome was acute myocardial infarction, revascularization, or death of cardiac or unknown cause within 3 months. To include patients in the study we stablish three premises: normal/no diagnosis of ACS in EKG, chest radiograph performed without an alternative diagnosis of ischemic heart disease (IHD) and negative troponin. To stablish the pretest probability (PTP) of IHD the Diamond-Forrest scale (DFS) was calculated according to the characteristics of the pain (typical/atypical/non-anginal), age and sex. If the PTP was from 15-65% a coronary CT was performed. Significant stenosis was considered if the decrease in vessel size in one or more vessels was >50%.

RESULTS: We included 232 patients (mean age 51.7 years, 74.1% male, 12.3% admitted to hospital). 48.1% presented typical angina, 12.3% atypical angina and 39.6% non-anginal pain according to the DFS. We calculate diagnostic accuracy of the Diamond Forest clinical decision rule (CDR) to select candidates for coronary CT, with the following characteristics: sensitivity 87.5% (95% confidence interval [CI] 69.0–95.7%), specificity 51.9% (95%CI 45.2–58.6%), positive predictive value 17.4% (95%CI 11.6–25.1%) and negative predictive value 97.3% (95%CI 92.4–99.1%). 46.1% had PTP <15% for IHD, 3 with significant coronary stenosis (SCE)> 50%. 43.1% had PTP 15-65%, 13 (13%) had SCE > 50%. 8.2% had PTP 66-85%, 31.6% had SCE > 50% and from 6 cases with PTP > 85%, 33.3% had IHD. In 4 cases cardiac catheterization was performed and it was not possible in 2 cases.

DISCUSSION: Coronary CT has been increasing its importance in the management of ACS being a fast, safe and efficient diagnostic tool for patients with low-intermediate risk of ACS in the ED. The DFS is not an adequate CDR to select candidates for coronary CT in patients with non-traumatic chest pain at the ED.


Magdalena CARRERAS, Veronica GARCÍA DE PEREDA, Iciar BARREÑA, Maria Victoria MONTEJO, Nora IBARGOYEN, Juan Carlos BAYON, Irma ARRIETA, Marta LAZARO, Ainhoa GANDIAGA, Eunate ARANA-ARRI (Berango, Spain)
Kokkali

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E42
11:10 - 12:40

General Emergency Medicine

Moderators: Raed ARAFAT (Romania), Said LARIBI (PU-PH, chef de pôle) (Tours, France)
11:10 - 11:40 Advances in the technologies and processes of care in emergency care. Tiziana MARGARIA STEFFEN (Speaker, Ireland)
11:40 - 12:10 Post traumatic stress disorder in the ED. Togay EVRIN (Speaker) (Speaker, Ankara, Turkey)
12:10 - 12:40 ARDS: The challenge for early intensive care in the ED. Juliusz JAKUBASZKO (Chair) (Speaker, Wroclaw, Poland)
MC-3

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D42
11:10 - 12:40

Choosing wisely in the ED

Moderators: Dr George NOTAS (DOCTOR) (HERAKLION, Greece), Michael RADEOS (USA)
11:10 - 11:40 Laboratory tests in the ED: Sometimes ‘Less is More’. Dr George NOTAS (DOCTOR) (Speaker, HERAKLION, Greece)
11:40 - 12:10 How can we reduce unnecessary radiology tests? Tony KAMBOURAKIS (Director Medical Services) (Speaker, Melbourne, Australia)
12:10 - 12:40 Focusing on the front door: Streaming strategies and pitfalls. Nikolas SBYRAKIS (Consultant Emergency Physician) (Speaker, Heraklion, Greece)
Skalkotas
12:40

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A43
12:40 - 13:40

EUSEM 2017 Closing Ceremony

Trianti Hall